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https://www.readbyqxmd.com/read/28732650/adjuvant-tamoxifen-and-exemestane-in-women-with-postmenopausal-early-breast-cancer-team-10-year-follow-up-of-a-multicentre-open-label-randomised-phase-3-trial
#1
Marloes G M Derks, Erik J Blok, Caroline Seynaeve, Johan W R Nortier, Elma Meershoek-Klein Kranenbarg, Gerrit-Jan Liefers, Hein Putter, Judith R Kroep, Daniel Rea, Annette Hasenburg, Christos Markopoulos, Robert Paridaens, Jan B E Smeets, Luc Y Dirix, Cornelis J H van de Velde
BACKGROUND: After 5 years of median follow-up, the Tamoxifen Exemestane Adjuvant Multinational (TEAM) trial reported no difference in disease-free survival between exemestane monotherapy and a sequential scheme of tamoxifen followed by exemestane in postmenopausal patients with early-stage, hormone receptor-positive breast cancer. As recurrence risk in hormone receptor-positive breast cancer remains linear beyond 5 years after diagnosis, we analysed long-term follow-up outcomes of this trial...
September 2017: Lancet Oncology
https://www.readbyqxmd.com/read/28713820/antioxidant-properties-of-natchez-and-triple-crown-blackberries-using-korean-traditional-winemaking-techniques
#2
Youri Joh, Niels Maness, William McGlynn
This research evaluated blackberries grown in Oklahoma and wines produced using a modified traditional Korean technique employing relatively oxygen-permeable earthenware fermentation vessels. The fermentation variables were temperature (21.6°C versus 26.6°C) and yeast inoculation versus wild fermentation. Wild fermented wines had higher total phenolic concentration than yeast fermented wines. Overall, wines had a relatively high concentration of anthocyanin (85-320 mg L(-1) malvidin-3-monoglucoside) and antioxidant capacity (9776-37845 µmol Trolox equivalent g(-1))...
2017: International journal of food science
https://www.readbyqxmd.com/read/28690676/radioguided-localisation-of-non-palpable-lesions-of-the-breast-in-costa-rica-review-of-results-of-our-first-800-patients-in-private-practice
#3
REVIEW
Marisel Aguilar, Sabrina Alfaro, Ricardo Aguilar
BACKGROUND: Surgical treatment of non-palpable breast lesions is controversial. At the European Institute of Oncology in Milan, Italy, Prof Umberto Veronesi introduced a new technique called the radioguided occult lesion localisation (ROLL) in 1996 to replace conventional methods and their disadvantages (Zurrida S, Galimberti V, and Monti S et al (1998) Radioguided localization of occult breast lesionsBreast7 11-13 https://doi.org/10.1016/S0960-9776(98)90044-3). Given the success experienced in that institution, the method became the technique of choice for the early diagnosis of breast cancer...
2017: Ecancermedicalscience
https://www.readbyqxmd.com/read/28449235/psychometric-properties-of-the-mental-health-and-social-inadaptation-assessment-for-adolescents-mia-in-a-population-based-sample
#4
Sylvana M Côté, Massimiliano Orri, Mara Brendgen, Frank Vitaro, Michel Boivin, Christa Japel, Jean R Séguin, Marie-Claude Geoffroy, Alexandra Rouquette, Bruno Falissard, Richard E Tremblay
We report on the psychometric properties of the Mental Health and Social Inadaptation Assessment for Adolescents (MIA), a self-report instrument for quantifying the frequency of mental health and psychosocial adaptation problems using a dimensional approach and based on the DSM-5. The instrument includes 113 questions, takes 20-25 minutes to answer, and covers the past 12 months. A population-based cohort of adolescents (n = 1443, age = 15 years; 48% males) rated the frequency at which they experienced symptoms of Attention Deficit Hyperactivity Disorder (ADHD), Conduct Disorder, Oppositional Defiant Disorder, Depression, Generalized Anxiety, Social Phobia, Eating Disorders (i...
April 27, 2017: International Journal of Methods in Psychiatric Research
https://www.readbyqxmd.com/read/28187302/a-kinetic-study-of-bitter-taste-receptor-sensing-using-immobilized-porcine-taste-bud-tissues
#5
Lihui Wei, Lixin Qiao, Guangchang Pang, Junbo Xie
At present, developing an efficient assay method for truly reflecting the real feelings of gustatory tissues is of great importance. In this study, a novel biosensor was fabricated to investigate the kinetic characteristics of the receptors in taste bud tissues sensing bitter substances for the first time. Porcine taste bud tissues were used as the sensing elements, and the sandwich-type sensing membrane was fixed onto a glassy carbon electrode for assembling the biosensor. With the developed sensor, the response currents induced by sucrose octaacetate, denatonium benzoate, and quercetin stimulating corresponding receptors were determined...
June 15, 2017: Biosensors & Bioelectronics
https://www.readbyqxmd.com/read/27236223/identification-of-lesion-images-from-gastrointestinal-endoscope-based-on-feature-extraction-of-combinational-methods-with-and-without-learning-process
#6
Ding-Yun Liu, Tao Gan, Ni-Ni Rao, Yao-Wen Xing, Jie Zheng, Sang Li, Cheng-Si Luo, Zhong-Jun Zhou, Yong-Li Wan
The gastrointestinal endoscopy in this study refers to conventional gastroscopy and wireless capsule endoscopy (WCE). Both of these techniques produce a large number of images in each diagnosis. The lesion detection done by hand from the images above is time consuming and inaccurate. This study designed a new computer-aided method to detect lesion images. We initially designed an algorithm named joint diagonalisation principal component analysis (JDPCA), in which there are no approximation, iteration or inverting procedures...
August 2016: Medical Image Analysis
https://www.readbyqxmd.com/read/26786818/associations-between-polymyalgia-rheumatica-and-giant-cell-arteritis-and-12-cardiovascular-diseases
#7
Mar Pujades-Rodriguez, Bram Duyx, Sara L Thomas, Dimitris Stogiannis, Liam Smeeth, Harry Hemingway
OBJECTIVES: Evidence of the association of polymyalgia rheumatica (PMR) and giant cell arteritis (GCA) with the full range of cardiovascular diseases (CVDs) is limited. We examined their relationship with the first clinical presentation of the 12 most common CVDs in an unselected population-based cohort of men and women. METHODS: We analysed CArdiovascular disease research using LInked Bespoke studies and Electronic health Records (CALIBER) data, which links primary care and hospital and mortality data in England, from 1997 to 2010...
March 2016: Heart: Official Journal of the British Cardiac Society
https://www.readbyqxmd.com/read/26745859/imaging-tests-for-the-diagnosis-and-staging-of-pancreatic-adenocarcinoma-a-meta-analysis
#8
Jonathan R Treadwell, Hanna M Zafar, Matthew D Mitchell, Kelley Tipton, Ursina Teitelbaum, Jane Jue
Imaging tests are central to the diagnosis and staging of pancreatic adenocarcinoma. We performed a systematic review and meta-analysis of the pertinent evidence on 5 imaging tests (computed tomography (CT), magnetic resonance imaging, CT angiography, endoscopic ultrasound with fine-needle aspiration, and combined positron emission tomography with CT). Searches of several databases up to March 1, 2014, yielded 9776 articles, and 24 provided comparative effectiveness of 2 or more imaging tests. Multiple reviewers applied study inclusion criteria, extracted data from each study, rated the risk of bias, and graded the strength of evidence...
July 2016: Pancreas
https://www.readbyqxmd.com/read/26594505/crystal-structure-of-hexa-kis-urea-%C3%AE%C2%BAo-chromium-iii-dichromate-bromide-monohydrate-from-synchrotron-x-ray-data
#9
Dohyun Moon, Shinnosuke Tanaka, Takashiro Akitsu, Jong-Ha Choi
The title bromide salt, [Cr{CO(NH2)2}6](Cr2O7)Br·H2O, is isotypic to the corresponding chloride salt. Within the complex cation, the Cr(III) atom is coordinated by six O atoms of six urea ligands, displaying a slightly distorted octa-hedral coordination environment. The Cr-O bond lengths involving the urea ligands are in the range 1.9534 (13)-1.9776 (12) Å. The Cr2O7 (2-) anion has a nearly staggered conformation, with a bridging angle of 130.26 (10)°. The individual components are arranged in rows extending parallel to [100]...
November 1, 2015: Acta Crystallographica. Section E, Crystallographic Communications
https://www.readbyqxmd.com/read/26396760/crystal-structure-of-bis-%C3%AE-bis-di-phenyl-phosphanyl-methane-%C3%AE%C2%BA-2-p-p-digold-i-dichloride-acetone-monosolvate-monohydrate
#10
Chien Ing Yeo, Yee Seng Tan, Edward R T Tiekink
In the title complex salt, [Au2{(C6H5)2PCH2P(C6H5)2}]Cl2·(CH3)2C=O·H2O, the dication forms an eight-membered {-PCPAu}2 ring with a transannular aurophilic inter-action [Au⋯Au = 2.9743 (2) Å]. The ring approximates a flattened boat conformation, with the two methyl-ene C atoms lying ca 0.58-0.59 Å above the least-squares plane defined by the Au2P4 atoms (r.m.s. deviation = 0.0849 Å). One Cl(-) anion functions as a weak bridge between the Au(I) atoms [Au⋯Cl = 2.9492 (13) and 2.9776 (12) Å]...
August 1, 2015: Acta Crystallographica. Section E, Crystallographic Communications
https://www.readbyqxmd.com/read/26238542/development-of-a-test-strip-for-rapid-detection-of-lactoperoxidase-in-raw-milk
#11
Hong-xia Che, Bo Tian, Li-na Bai, Li-ming Cheng, Li-li Liu, Xiao-na Zhang, Zhan-mei Jiang, Xiao-xi Xu
Traditional methods for detecting lactoperoxidase (LP) are complex and time-consuming, so a test strip was made based on the enzymatic reaction principle to enable quick and convenient detection of LP in raw milk. In this study 0.1 mol/L citric acid (CA)/0.2 mol/L disodium hydrogen phosphate (NaP) buffer solution (pH 5.0), 22 mmol/L 3,3',5,5'-tetramethylbenzidine (TMB), 0.6 mmol/L hydrogen peroxide (H2O2), and 0.5% Tween-20 or 0.3% cetyltrimethyl ammonium bromide (CTAB) were optimal for preparing a quick, sensitive, and accurate LP test strip...
August 2015: Journal of Zhejiang University. Science. B
https://www.readbyqxmd.com/read/25737131/diagnostic-value-of-18-f-fdg-pet-ct-in-detecting-local-recurrent-colorectal-cancer-a-pooled-analysis-of-26-individual-studies
#12
Tao Yu, Nan Meng, Da Chi, Yingjie Zhao, Kunzhe Wang, Yahong Luo
Fluorine 18 fluorodeoxyglucose ((18)F-FDG) positron emission tomography (PET)/computed tomography (CT) has emerged as a new modality for colorectal cancer (CRC) patients. The aim of this meta-analysis was to assess the diagnostic value of (18)F-FDG PET/CT in detecting local recurrence in patients with CRC. We searched PubMed, Medline, Embase, and ISI databases to collect articles in English that evaluated the diagnostic value of (18)F-FDG PET/CT in patients with CRC. Two reviewers independently assessed the methodological quality of each study using the quality assessment of diagnostic accuracy studies tool...
June 2015: Cell Biochemistry and Biophysics
https://www.readbyqxmd.com/read/24053923/-changes-of-serum-neuron-specific-enolase-and-serum-ferritin-levels-in-patients-with-pneumoconiosis
#13
Feng-jie Jiang, Shun-ji Gao, Jun Meng, Gui-fang Li, Xiao-juan Sun
OBJECTIVE: To investigate the changes in serum neuron-specific enolase (NSE) and serum ferritin (SF) in patients with pneumoconiosis and their relationship with the onset of pneumoconiosis. METHODS: The serum NSE and SF levels in the peripheral blood of patients with pneumoconiosis were measured by electrochemical fluorescence immunoassay. RESULTS: The patients with first-stage pneumoconiosis and second-stage pneumoconiosis had significantly higher serum NSE and SF levels than the control group (23...
July 2013: Chinese Journal of Industrial Hygiene and Occupational Diseases
https://www.readbyqxmd.com/read/23378089/detection-of-layer-by-layer-self-assembly-multilayer-films-by-low-temperature-plasma-mass-spectrometry
#14
Xiangyu Xu, Na Na, Jiying Wen, Jin Ouyang
The detection of layer-by-layer self-assembly multilayer films was carried out using low-temperature plasma (LTP) mass spectrometry (MS) under ambient conditions. These multilayer films have been prepared on quartz plates through the alternate assembling of oppositely charged 4-aminothiophenol (4-ATP) capped Au particles and thioglycolic acid (TGA) capped Ag particles. An LTP probe was used for direct desorption and ionization of chemical components on the films. Without the complicated sample preparation, the structure information of 4-ATP and TGA on films was studied by LTP-MS...
February 2013: Journal of Mass Spectrometry: JMS
https://www.readbyqxmd.com/read/23156760/-rapid-determination-of-fatty-acids-in-soybean-oils-by-transmission-reflection-near-infrared-spectroscopy
#15
Tao Song, Feng-ping Zhang, Yao-min Liu, Zong-wen Wu, You-rui Suo
In the present research, a novel method was established for determination of five fatty acids in soybean oil by transmission reflection-near infrared spectroscopy. The optimum conditions of mathematics model of five components (C16:0, C18:0, C18:1, C18:2 and C18:3) were studied, including the sample set selection, chemical value analysis, the detection methods and condition. Chemical value was analyzed by gas chromatography. One hundred fifty eight samples were selected, 138 for modeling set, 10 for testing set and 10 for unknown sample set...
August 2012: Guang Pu Xue Yu Guang Pu Fen Xi, Guang Pu
https://www.readbyqxmd.com/read/22163450/a-potentiometric-formaldehyde-biosensor-based-on-immobilization-of-alcohol-oxidase-on-acryloxysuccinimide-modified-acrylic-microspheres
#16
Yew Pei Ling, Lee Yook Heng
A new alcohol oxidase (AOX) enzyme-based formaldehyde biosensor based on acrylic microspheres has been developed. Hydrophobic poly(n-butyl acrylate-N-acryloxy-succinimide) [poly(nBA-NAS)] microspheres, an enzyme immobilization matrix, was synthesized using photopolymerization in an emulsion form. AOX-poly(nBA-NAS) microspheres were deposited on a pH transducer made from a layer of photocured and self-plasticized polyacrylate membrane with an entrapped pH ionophore coated on a Ag/AgCl screen printed electrode (SPE)...
2010: Sensors
https://www.readbyqxmd.com/read/20854732/-correlation-between-in-vitro-bacterial-growth-velocity-of-blood-of-patients-with-clinical-parameters-and-prognosis-in-patients-with-escherichia-coli-bacteremia
#17
Shi-ning Bo, Yong-zhong Ning, Xi Zhu, Gai-qi Yao
OBJECTIVE: To identify the clinical and laboratory parameters correlating with speed of bacterial growth in culture and independent risk factors of in-hospital mortality in patients with Escherichia coli bacteremia. METHODS: This retrospective study was conducted at Beijing University Third Hospital. The medical records and microbiological database of the patients diagnosed as Escherichia coli bacteremia between January 2007 and December 2009 were collected. The parameter of time to positivity (TTP) was used to be a surrogate marker of bacterial growth...
September 2010: Zhongguo Wei Zhong Bing Ji Jiu Yi Xue, Chinese Critical Care Medicine, Zhongguo Weizhongbing Jijiuyixue
https://www.readbyqxmd.com/read/20304031/early-event-related-potentials-changes-during-simple-mental-calculation-in-chinese-older-adults-with-mild-cognitive-impairment-a-case-control-study
#18
Xiuyan Li, Yuanyuan Zhang, Lei Feng, Qinghui Meng
The aim was to examine early event-related potential (ERP) changes during mental arithmetic calculation task in mild cognitive impairment patients compared to healthy elderly. 16 mild cognitive impairment (MCI) subjects and 16 healthy Chinese older adults were studied. Event-related potentials were elicited using a simple mental calculation task. Performance on arithmetic calculation task, and the latency and amplitude of early event-related potential components (N1, P1, N170, and P2) were compared between the two groups...
May 7, 2010: Neuroscience Letters
https://www.readbyqxmd.com/read/20137482/development-of-sympathetic-ophthalmia-following-globe-injury
#19
Ying Zhang, Mao-Nian Zhang, Cai-Hui Jiang, Yi Yao
BACKGROUND: Sympathetic ophthalmia (SO), a rare, bilateral, diffuse granulomatous uveitis, usually occurs after open globe injury or intraocular surgery. We sought to identify the risk factors for the development of SO after open globe injury and describe their demographic and clinical features and outcomes of treatments. METHODS: A retrospective study of inpatients with globe injury in 15 tertiary referral hospitals of China from January 2001 to December 2005 was conducted...
December 20, 2009: Chinese Medical Journal
https://www.readbyqxmd.com/read/19702246/dimethylammonium-hexanoate-stabilized-rhodium-0-nanoclusters-identified-as-true-heterogeneous-catalysts-with-the-highest-observed-activity-in-the-dehydrogenation-of-dimethylamine-borane
#20
Mehmet Zahmakiran, Saim Ozkar
Herein we report the discovery of a superior dimethylamine-borane dehydrogenation catalyst, more active than the prior best heterogeneous catalyst (Jaska, C. A.; Manners, I. J. Am. Chem. Soc. 2004, 126, 9776) reported to date for the dehydrogenation of dimethylamine-borane. The new catalyst system consists of rhodium(0) nanoclusters stabilized by C(5)H(11)COO(-) anions and Me(2)H(2)N(+) cations and can reproducibly be formed from the reduction of rhodium(II) hexanoate during dehydrogenation of dimethylamine-borane at room temperature...
September 21, 2009: Inorganic Chemistry
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