keyword
MENU ▼
Read by QxMD icon Read
search

Ocd treatment

keyword
https://www.readbyqxmd.com/read/28642831/treatment-of-hypochondriasis-in-two-schizophrenia-patients-using-clozapine
#1
Antonio Tundo, Luca Proietti, Rocco de Filippis
Hypochondriasis (HYPO), an obsessive-compulsive spectrum disorder, is frequent in patients with schizophrenia (SCH) (20%), especially among those treated with clozapine (36.7%). Treatment options for OCS/OCD in patients under clozapine (CLZ) include combining clozapine with amisulpride/aripiprazole or a mood stabilizer, augmenting clozapine with a serotoninergic reuptake inhibitor, adding cognitive behavioural therapy, and gradually reducing dosage. No treatments have been proposed for HYPO in patients using clozapine so we examine these options in 2 cases and report the results...
2017: Case Reports in Psychiatry
https://www.readbyqxmd.com/read/28639852/osteochondritis-dissecans-etiology-pathology-and-imaging-with-a-special-focus-on-the-knee-joint
#2
Juergen Bruns, Mathias Werner, Christian Habermann
This article is a review of the current understanding of the etiology, pathogenesis, and how to diagnose and treat knee osteochondritis dissecans (OCD) followed by an analysis of and outcomes of the treatments available. OCD is seen in children and adolescents with open growth plates (juvenile OCD) and adults with closed growth plates (adult OCD). The etiology of OCD lesions remains unclear and is characterized by an aseptic necrosis in the subchondral bone area. Mechanical factors seem to play an important role...
June 1, 2017: Cartilage
https://www.readbyqxmd.com/read/28638200/brain-gamma-aminobutyric-acid-gaba-concentration-of-the-prefrontal-lobe-in-unmedicated-patients-with-obsessive-compulsive-disorder-a-research-of-magnetic-resonance-spectroscopy
#3
Zongfeng Zhang, Qing Fan, Yanle Bai, Zhen Wang, Haiyin Zhang, Zeping Xiao
BACKGROUND: In recent years, a large number of neuroimaging studies found that the Cortico-Striato- Thalamo-Cortical circuit (CSTC), including the prefrontal lobe, a significant part of CSTC, has disturbance metabolically in patients with Obsessive-Compulsive Disorder (OCD). AIM: Explore the correlation between the neuro-metabolic features and clinical characteristics of OCD patients using magnetic resonance spectroscopy technology. METHODS: 88 patients with OCD who were not received medication and outpatient treatment for 8 weeks and 76 health controls were enrolled, there was no significant difference in gender, age or education level between the two groups...
October 25, 2016: Shanghai Archives of Psychiatry
https://www.readbyqxmd.com/read/28633778/results-of-hemicap-%C3%A2-implantation-as-a-salvage-procedure-for-osteochondral-lesions-of-the-talus
#4
Sarah Ettinger, Christina Stukenborg-Colsman, Hazibullah Waizy, Christoph Becher, Daiwei Yao, Leif Claassen, Yvonne Noll, Christian Plaass
Osteochondral defects (OCDs) of the talus remain a surgical challenge, especially after failed primary treatment. The aim of the present study was to examine the clinical outcomes after HemiCAP(®) implantation for OCDs of the medial talar dome after failed previous surgery. Our retrospective study included 11 patients, who had undergone surgery from June 2009 to September 2012 for an OCD of the medial talar dome and received a HemiCAP(®) on the talus after failed previous surgery for OCD. The data were acquired using patients' medical records and standardized questionnaires, including the Foot and Ankle Outcome Score (FAOS), University of California at Los Angeles (UCLA) activity score, EQ-5D, numerical rating scale (NRS), and Short-Form 36-item Health Survey (SF-36)...
July 2017: Journal of Foot and Ankle Surgery: Official Publication of the American College of Foot and Ankle Surgeons
https://www.readbyqxmd.com/read/28632120/basolateral-amygdala-ventromedial-prefrontal-cortex-connectivity-predicts-cognitive-behavioural-therapy-outcome-in-adults-with-obsessive-compulsive-disorder
#5
Miquel A Fullana, Xi Zhu, Pino Alonso, Narcís Cardoner, Eva Real, Clara López-Solà, Cinto Segalàs, Marta Subirà, Hanga Galfalvy, José M Menchón, H Blair Simpson, Rachel Marsh, Carles Soriano-Mas
BACKGROUND: Cognitive behavioural therapy (CBT), including exposure and ritual prevention, is a first-line treatment for obsessive-compulsive disorder (OCD), but few reliable predictors of CBT outcome have been identified. Based on research in animal models, we hypothesized that individual differences in basolateral amygdala-ventromedial prefrontal cortex (BLA-vmPFC) communication would predict CBT outcome in patients with OCD. METHODS: We investigated whether BLA-vmPFC resting-state functional connectivity (rs-fc) predicts CBT outcome in patients with OCD...
June 20, 2017: Journal of Psychiatry & Neuroscience: JPN
https://www.readbyqxmd.com/read/28617566/randomized-double-blind-placebo-controlled-trial-of-n-acetylcysteine-augmentation-for-treatment-resistant-obsessive-compulsive-disorder
#6
Daniel L C Costa, Juliana B Diniz, Guaraci Requena, Marinês A Joaquim, Christopher Pittenger, Michael H Bloch, Euripedes C Miguel, Roseli G Shavitt
OBJECTIVE: To evaluate the efficacy of serotonin reuptake inhibitor (SRI) augmentation with N-acetylcysteine (NAC), a glutamate modulator and antioxidant medication, for treatment-resistant obsessive-compulsive disorder (OCD). METHODS: We conducted a randomized, double-blind, placebo-controlled, 16-week trial of NAC (3,000 mg daily) in adults (aged 18-65 years) with treatment-resistant OCD, established according to DSM-IV criteria. Forty subjects were recruited at an OCD-specialized outpatient clinic at a tertiary hospital (May 2012-October 2014)...
June 6, 2017: Journal of Clinical Psychiatry
https://www.readbyqxmd.com/read/28615780/converging-neurobiological-evidence-in-primary-polydipsia-resembling-obsessive-compulsive-disorder
#7
Karthick Subramanian, Tess Maria Rajan, Vikas Menon, Ravi Philip Rajkumar
Compulsive water drinking can have phenomenological and pharmacotherapeutic similarities with obsessive-compulsive disorder (OCD). Substantiating neurobiological evidence is lacking for such an association. We report a patient who was referred with a diagnosis of primary polydipsia with no signs of organic pathology in structural neuroimaging. However, positron emission tomography revealed basal ganglia hypometabolism indicating that primary polydipsia with compulsive water drinking is neurobiologically related to OCD...
May 2017: Indian Journal of Psychological Medicine
https://www.readbyqxmd.com/read/28601668/developmental-and-clinical-predictors-of-comorbidity-for-youth-with-obsessive-compulsive-disorder
#8
Tara S Peris, Michelle Rozenman, R Lindsey Bergman, Susanna Chang, Joseph O'Neill, John Piacentini
OBJECTIVE: To date, few studies of childhood obsessive compulsive disorder (OCD) have been adequately powered to examine patterns and predictors of comorbidity, despite the frequency with which it occurs. We address this gap, drawing on a large sample of youth with OCD who were systematically assessed through research and clinical programs in a university-based specialty program for children and adolescents with OCD. We examine patterns of comorbidity across different epochs of development and predict specific classes of OCD (comorbidity internalizing/externalizing/both) from key demographic and clinical variables that may be useful in guiding individualized treatment...
October 2017: Journal of Psychiatric Research
https://www.readbyqxmd.com/read/28592342/treatment-of-obsessive-compulsive-disorder-and-excessive-reassurance-seeking-in-an-older-adult-a-single-case-quasi-experimental-design
#9
Brynjar Halldorsson, Paul M Salkovskis
BACKGROUND: Cognitive behavioural interventions for excessive reassurance seeking (ERS) typically focus on encouraging individuals to refrain from seeking any reassurance and in some cases banning caregivers (e.g. family members) from providing it. However, this blanket consideration that reassurance is a bad thing that should simply be stopped may not always be appropriate or helpful. Cognitive behavioural treatment (CBT) targeting ERS by helping the sufferer to shift from seeking reassurance to seeking support may be a promising treatment intervention...
June 8, 2017: Behavioural and Cognitive Psychotherapy
https://www.readbyqxmd.com/read/28590207/an-integrative-approach-to-treatment-resistant-obsessive-compulsive-disorder
#10
Luke Sy-Cherng Woon, Anita Kanapathy, Hazli Zakaria, César A Alfonso
Obsessive-compulsive disorder (OCD) is a debilitating psychiatric disorder that often runs a chronic unremitting course. Treatment outcomes can be unsatisfactory despite the availability of various somatic and psychological therapies. Psychodynamic psychotherapy in combination with cognitive behavioral therapy (CBT) with exposure and response prevention (ERP) could help patients with treatment-resistant OCD achieve better outcomes. An integrative approach can help patients gain insight, strengthen the therapeutic alliance, improve treatment adherence, and provide symptomatic relief when other treatments seem insufficient or have failed...
2017: Psychodynamic Psychiatry
https://www.readbyqxmd.com/read/28588509/behavioral-effects-of-a-novel-benzofuranyl-piperazine-serotonin-2c-receptor-agonist-suggest-a-potential-therapeutic-application-in-the-treatment-of-obsessive-compulsive-disorder
#11
Michelle M Rodriguez, Carl Overshiner, J David Leander, Xia Li, Denise Morrow, Richard G Conway, David L Nelson, Karin Briner, Jeffrey M Witkin
Selective serotonin reuptake inhibitors (SSRIs) are the only effective pharmacological treatments for obsessive-compulsive disorder (OCD). Nonetheless, their generally limited efficacy, side-effects, and delayed onset of action require improved medications for this highly prevalent disorder. Preclinical and clinical findings have suggested serotonin2C (5-HT2C) receptors as a potential drug target. Data in rats and mice are presented here on the effects of a novel 5-HT2C receptor agonist ((3S)-3-Methyl-1-[4-(trifluoromethyl)-7-benzofuranyl]-piperazine) (CPD 1) with high potency and full efficacy at 5-HT2C receptors and less potency and partial agonism at 5-HT2A and 5-HT2B receptors...
2017: Frontiers in Psychiatry
https://www.readbyqxmd.com/read/28588105/a-register-based-13-year-to-43-year-follow-up-of-70-patients-with-obsessive-compulsive-disorder-treated-with-capsulotomy
#12
Christian Rück, Johan K Larsson, David Mataix-Cols, Rickard Ljung
OBJECTIVES: Little is known about the long-term medical status of patients with severe obsessive-compulsive disorder (OCD) undergoing capsulotomy, a neurosurgical last-resort treatment. The present study used national registers to identify all operated patients with OCD in Sweden and evaluated their long-term medical status, including mortality, hospital admissions and psychotropic medication after capsulotomy for OCD. DESIGN: Register-based long-term follow-up cohort study...
June 6, 2017: BMJ Open
https://www.readbyqxmd.com/read/28577707/management-of-osteochondritis-dissecans-lesions-of-the-knee-elbow-and-ankle
#13
REVIEW
Kathryn L Bauer, John D Polousky
Although osteochondritis dissecans (OCD) has been a recognized condition for more than 100 years, our understanding of the etiology, natural history, and treatment remains poorly characterized. OCD most commonly affects the knee, followed by the elbow and ankle. Adolescents and young adults are most commonly affected. Patients present with vague, often intermittent symptoms and generally have no history of acute injury. Although diagnosis can be made with plain radiographs, treatment decisions are generally based on MRI...
July 2017: Clinics in Sports Medicine
https://www.readbyqxmd.com/read/28577065/treatment-of-talus-osteochondral-defects-in-chronic-lateral-unstable-ankles-small-sized-lateral-chondral-lesions-had-good-clinical-outcomes
#14
Hong Li, Yinghui Hua, Hongyun Li, Shengkun Li, Kui Ma, Shiyi Chen
PURPOSE: To assess and compare the clinical and MRI outcomes of patients with talus osteochondral defect (OCD) and patients without OCD in a cohort with chronic lateral ankle instability. METHODS: All patients who underwent open or arthroscopic anterior talofibular ligament repair of the lateral ligament complex by a single surgeon were included in this study. Ankle arthroscopic surgery was initially performed to manage any intra-articular OCD, including debridement and microfracture...
June 2, 2017: Knee Surgery, Sports Traumatology, Arthroscopy: Official Journal of the ESSKA
https://www.readbyqxmd.com/read/28569409/there-is-an-app-for-that-the-current-state-of-mobile-applications-apps-for-dsm-5-obsessive-compulsive-disorder-posttraumatic-stress-disorder-anxiety-and-mood-disorders
#15
REVIEW
Michael Van Ameringen, Jasmine Turna, Zahra Khalesi, Katrina Pullia, Beth Patterson
Mental health apps are viewed as a promising modality to extend the reach of mental health care beyond the clinic. They do so by providing a means of assessment, tracking, and treatment through a smartphone. Given that nearly 2/3 of the American population owns a smartphone, mental health apps offer the possibility of overcoming treatment barriers such as geographic location or financial barriers. Unfortunately, the excitement surrounding mental health apps may be premature as the current supporting literature regarding their efficacy is limited...
June 1, 2017: Depression and Anxiety
https://www.readbyqxmd.com/read/28565937/app-guided-exposure-and-response-prevention-for-obsessive-compulsive-disorder-an-open-pilot-trial
#16
Christina L Boisseau, Carly M Schwartzman, Jessica Lawton, Maria C Mancebo
Although effective treatments for obsessive-compulsive disorder (OCD) exist, there are significant barriers to receiving evidence-based care. Mobile health applications (Apps) offer a promising way of overcoming these barriers by increasing access to treatment. The current study investigated the feasibility, acceptability, and preliminary efficacy of LiveOCDFree, an App designed to help OCD patients conduct exposure and response prevention (ERP). Twenty-one participants with mild to moderate symptoms of OCD were enrolled in a 12-week open trial of App-guided self-help ERP...
June 1, 2017: Cognitive Behaviour Therapy
https://www.readbyqxmd.com/read/28552055/promising-treatments-for-obsessive-compulsive-disorder-a-call-for-additional-research
#17
Lorrin M Koran, Elias Aboujaoude
Many patients with OCD respond partially or not at all to standard medications and cognitive behavioral therapy approaches, making alternate treatments necessary. We review the preliminary evidence that exists in support of the use of stimulants, high-dose caffeine, opiates, memantine, ondansetron, ketamine, and transcranial magnetic stimulation in some patients with OCD. Although limited by small or modest sample sizes, open-label study designs, and brief follow-up periods, studies suggest that each of these strategies can help some patients who have inadequately responded to first-line treatments...
May 26, 2017: Current Medicinal Chemistry
https://www.readbyqxmd.com/read/28549337/the-relation-of-childhood-trauma-to-suicide-ideation-in-patients-suffering-from-obsessive-compulsive-disorder-with-lifetime-suicide-attempts
#18
Vahid Khosravani, Zoleikha Kamali, Razieh Jamaati Ardakani, Mehdi Samimi Ardestani
The aim of this study was to evaluate the relations of childhood trauma (CT) and obsessive-compulsive (OC) symptom dimensions to suicide ideation in patients with obsessive-compulsive disorder (OCD). Seventy OCD outpatients with lifetime suicide attempts and 60 controls were included. Participants completed the Scale for Suicide Ideation (SSI), the Childhood Trauma Questionnaire-Short Form (CTQ-SF), the Yale-Brown Obsessive Compulsive Scale (Y-BOCS), the Dimensional Obsessive-Compulsive Scale (DOCS) and the Depression Anxiety Stress Scales (DASS-21)...
May 20, 2017: Psychiatry Research
https://www.readbyqxmd.com/read/28545371/a-psycho-behavioral-perspective-on-modelling-obsessive-compulsive-disorder-ocd-in-animals-the-role-of-context
#19
De Wet Wolmarans, Dan J Stein, Brian H Harvey
Obsessive-compulsive disorder is a heterogeneous and debilitating condition, characterized by intrusive thoughts and compulsive repetition. Animal models of OCD are important tools that have the potential to contribute significantly to our understanding of the condition. Although there is consensus that pre-clinical models are valuable in elucidating the underlying neurobiology in psychiatric disorders, the current paper attempts to prompt ideas on how interpretation of animal behavior can be expanded upon to more effectively converge with the human disorder...
May 23, 2017: Current Medicinal Chemistry
https://www.readbyqxmd.com/read/28539952/executive-dysfunction-in-obsessive-compulsive-disorder-and-anterior-cingulate-based-resting-state-functional-connectivity
#20
Je-Yeon Yun, Joon Hwan Jang, Wi Hoon Jung, Na Young Shin, Sung Nyun Kim, Jae Yeon Hwang, Jun Soo Kwon
OBJECTIVE: Executive dysfunction might be an important determinant for response to pharmacotherapy in obsessive-compulsive disorder (OCD), and could be sustained independently of symptom relief. The anterior cingulate cortex (ACC) has been indicated as a potential neural correlate of executive functioning in OCD. The present study examined the brain-executive function relationships in OCD from the ACC-based resting state functional connectivity networks (rs-FCNs), which reflect information processing mechanisms during task performance...
May 2017: Psychiatry Investigation
keyword
keyword
104930
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"