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https://www.readbyqxmd.com/read/28926479/fatigue-following-traumatic-brain-injury-in-children-and-adolescents-a-longitudinal-follow-up-6-to-12-months-after-injury
#1
Alison Crichton, Vicki Anderson, Ed Oakley, Mardee Greenham, Stephen Hearps, Carmel Delzoppo, Miriam H Beauchamp, James S Hutchison, Anne-Marie Guerguerian, Kathy Boutis, Franz E Babl
BACKGROUND: Longitudinal fatigue data in children suffering from traumatic brain injury (TBI) are lacking. OBJECTIVES: To examine the effects of time postinjury (6-12 months) and injury severity on fatigue after childhood TBI. Secondarily, we compared fatigue 12 months postinjury against published control data. SETTING: Three tertiary children's hospitals across Australia (n = 1) and Canada (n = 2). PARTICIPANTS: Parents (n = 109) of children (mean [M] = 9...
September 18, 2017: Journal of Head Trauma Rehabilitation
https://www.readbyqxmd.com/read/28926398/association-of-a-3-untranslated-region-polymorphism-in-pcsk9-with-hiv-viral-load-and-cd4-levels-in-hiv-hepatitis-c-virus-co-infected-women
#2
Mark H Kuniholm, Hua Liang, Kathryn Anastos, Deborah Gustafson, Seble Kassaye, Marek Nowicki, Beverly E Sha, Emilia J Pawlowski, Stephen J Gange, Bradley E Aouizerat, Tatiana Pushkarsky, Michael I Bukrinsky, Vinayaka R Prasad
OBJECTIVE: To assess variation in genes that regulate cholesterol metabolism in relation to the natural history of HIV infection. DESIGN: Cross-sectional and longitudinal analysis of the Women's Interagency HIV Study (WIHS). METHODS: We examined 2,050 single nucleotide polymorphisms (SNPs) in 19 genes known to regulate cholesterol metabolism in relation to HIV viral load and CD4 T cell levels in a multiracial cohort of 1,066 antiretroviral therapy (ART) naïve women...
September 18, 2017: AIDS
https://www.readbyqxmd.com/read/28926003/age-of-first-exposure-to-american-football-and-long-term-neuropsychiatric-and-cognitive-outcomes
#3
M L Alosco, A B Kasimis, J M Stamm, A S Chua, C M Baugh, D H Daneshvar, C A Robbins, M Mariani, J Hayden, S Conneely, R Au, A Torres, M D McClean, A C McKee, R C Cantu, J Mez, C J Nowinski, B M Martin, C E Chaisson, Y Tripodis, R A Stern
Previous research suggests that age of first exposure (AFE) to football before age 12 may have long-term clinical implications; however, this relationship has only been examined in small samples of former professional football players. We examined the association between AFE to football and behavior, mood and cognition in a large cohort of former amateur and professional football players. The sample included 214 former football players without other contact sport history. Participants completed the Brief Test of Adult Cognition by Telephone (BTACT), and self-reported measures of executive function and behavioral regulation (Behavior Rating Inventory of Executive Function-Adult Version Metacognition Index (MI), Behavioral Regulation Index (BRI)), depression (Center for Epidemiologic Studies Depression Scale (CES-D)) and apathy (Apathy Evaluation Scale (AES))...
September 19, 2017: Translational Psychiatry
https://www.readbyqxmd.com/read/28925333/depression-and-cognitive-function-in-mild-cognitive-impairment-a-1-year-follow-up-study
#4
Seoyoung Yoon, Cheolmin Shin, Changsu Han
BACKGROUND: The coexistence of depression with mild cognitive impairment (MCI) seems to increase the risk of dementia. However, the explanations of that relationship have been inconsistent. We investigated cognitive profiles in patients with MCI with and without depression and whether changes in depression symptoms affect cognition longitudinally. METHODS: For the study, 161 patients with MCI were divided into a depressed group (D+) and a nondepressed group (D-)...
September 2017: Journal of Geriatric Psychiatry and Neurology
https://www.readbyqxmd.com/read/28925286/vocal-function-exercises-for-normal-voice-the-effects-of-varying-dosage
#5
Maria Bane, Vrushali Angadi, Emily Dressler, Richard Andreatta, Joseph Stemple
PURPOSE: This study examined the effect of varying dosage of vocal function exercise (VFE) home practice on attainment of pre-established maximum phonation time (MPT) goals in individuals with normal voice. High dosage VFE practice was expected to result in greatest MPT. The overarching goal of this study was to contribute to a VFE dosage-response curve, potentially including a point of observable toxicity. METHOD: Twenty-eight females ages 18-25 with normal voice participated in this pre-post longitudinal group study...
September 19, 2017: International Journal of Speech-language Pathology
https://www.readbyqxmd.com/read/28925098/identification-of-the-trajectory-of-functional-decline-for-advance-care-planning-in-a-nursing-home-population
#6
Suanne Lawrence, Andrew Robinson, Kathy Eagar
OBJECTIVE: To identify diagnostic groups and the form of the trajectory of functional decline that has the potential to enhance advance care planning (ACP) in a nursing home (NH) population. METHODS: Retrospective, longitudinal study with dependent variable (function) derived from the Resident Classification Scale (RCS), 1997-2008. Trajectory modelling used linear and curvilinear terms. RESULTS: The organ failure or other residents have a linear average functional decline...
September 2017: Australasian Journal on Ageing
https://www.readbyqxmd.com/read/28924621/an-altered-scaffold-for-information-processing-cognitive-control-development-in-adolescents-with-autism
#7
Marjorie Solomon, Jeremy Hogeveen, Lauren Libero, Christine Nordahl
We investigated how cognitive neuroscientific studies during the last decade have advanced understanding of cognitive control from adolescence to young adulthood in individuals with autism spectrum disorder (ASD). To do so, we conducted a selective review of the larger structural, resting state, and diffusion imaging studies of brain regions and networks related to cognitive control that have been conducted since 2007 in individuals with ASD and typical development (TYP) ages 10 to 30 years that examined how these regions and networks support behavioral and task-based fMRI performance on tasks assessing cognitive control during this period...
September 2017: Biological Psychiatry: Cognitive Neuroscience and Neuroimaging
https://www.readbyqxmd.com/read/28924566/comparison-of-oxyhemoglobin-and-deoxyhemoglobin-signal-reliability-with-and-without-global-mean-removal-for-digit-manipulation-motor-tasks
#8
Swethasri Dravida, Jack Adam Noah, Xian Zhang, Joy Hirsch
Functional near-infrared spectroscopy (fNIRS) could be well suited for clinical use, such as measuring neural activity before and after treatment; however, reliability and specificity of fNIRS signals must be ensured so that differences can be attributed to the intervention. This study compared the test-retest and longitudinal reliability of oxyhemoglobin and deoxyhemoglobin signals before and after spatial filtering. In the test-retest experiment, 14 participants were scanned on 2 days while performing four right-handed digit-manipulation tasks...
January 2018: Neurophotonics
https://www.readbyqxmd.com/read/28923933/longitudinal-identification-of-clinically-distinct-neurophenotypes-in-young-children-with-fragile-x-syndrome
#9
Jennifer L Bruno, David Romano, Paul Mazaika, Amy A Lightbody, Heather Cody Hazlett, Joseph Piven, Allan L Reiss
Fragile X syndrome (FXS), due to mutations of the FMR1 gene, is the most common known inherited cause of developmental disability. The cognitive, behavioral, and neurological phenotypes observed in affected individuals can vary considerably, making it difficult to predict outcomes and determine the need for interventions. We sought to examine early structural brain growth as a potential marker for identification of clinically meaningful subgroups. Participants included 42 very young boys with FXS who completed a T1-weighted anatomical MRI and cognitive/behavioral assessment at two longitudinal time points, with mean ages of 2...
September 18, 2017: Proceedings of the National Academy of Sciences of the United States of America
https://www.readbyqxmd.com/read/28923198/the-epidemiology-of-sleep-and-obesity
#10
REVIEW
Rachel P Ogilvie, Sanjay R Patel
Sleep is a state of consciousness that is preserved across animal species whose exact function is not yet clear but which has a vital impact on health and well-being. Epidemiological evidence suggests sleep duration in both children and adults has been decreasing over the past half-century, while at the same time rates of overweight and obesity have been increasing. Short sleep duration along with other dimensions of poor sleep has been associated with obesity both cross-sectionally and longitudinally. These data suggest a potential causal relationship between poor sleep and greater rates of weight gain that may be related to effects of sleep on dietary intake or physical activity...
October 2017: Sleep Health
https://www.readbyqxmd.com/read/28923172/handgrip-strength-is-associated-with-but-poorly-predicts-disability-in-older-women-with-acute-low-back-pain-a-12-month-follow-up-study
#11
Diogo Carvalho Felício, Juliano Bergamaschine Mata Diz, Daniele Sirineu Pereira, Bárbara Zille de Queiroz, Juscélio Pereira de Silva, Bruno de Souza Moreira, Vinícius Cunha Oliveira, Leani Souza Máximo Pereira
BACKGROUND: Older women with low back pain (LBP) constitute a special subpopulation at risk of severe and permanent disability. It is important to identify factors limiting functionality in this population in order to reduce costs and improve both prevention and intervention. Handgrip strength (HGS) is a biomarker of aging associated with several adverse health outcomes, but long-term associations with disability in older patients with LBP are not known. OBJECTIVE: To examine whether HGS predicts disability in older women with acute low back pain (LBP)...
October 2017: Maturitas
https://www.readbyqxmd.com/read/28922942/preoperative-psychosocial-factors-predicting-patient-s-functional-recovery-after-total-knee-or-total-hip-arthroplasty-a-systematic-review
#12
Anouck N Bletterman, Marcella E de Geest-Vrolijk, Johanna E Vriezekolk, Maria W Nijhuis-van der Sanden, Nico Lu van Meeteren, Thomas J Hoogeboom
OBJECTIVE: To evaluate the predictive value of preoperative psychosocial factors on the perceived and observed postoperative patient's functional recovery during the post-hospital phase and up to 12 months after hospital discharge of patients who underwent total knee or total hip arthroplasty. METHODS: A systematic review was performed. MEDLINE, CINAHL, EMBASE and PsychINFO were systematically screened in order to find prospective longitudinal studies. Risk of bias was assessed using a modified version of a 27-item checklist for prognostic studies, as previously used by Veerbeek...
September 1, 2017: Clinical Rehabilitation
https://www.readbyqxmd.com/read/28922650/constitutive-modeling-of-the-passive-inflation-extension-behavior-of-the-swine-colon
#13
Bhavesh Patel, Huan Chen, Aashish Ahuja, Joshua F Krieger, Jillian Noblet, Sean Chambers, Ghassan S Kassab
In the present work, we propose the first structural constitutive model of the passive mechanical behavior of the swine colon that is validated against physiological inflation-extension tests, and accounts for residual strains. Sections from the spiral colon and the descending colon were considered to investigate potential regional variability. We found that the proposed constitutive model accurately captures the passive inflation-extension behavior of both regions of the swine colon (coefficient of determination R(2)=0...
August 31, 2017: Journal of the Mechanical Behavior of Biomedical Materials
https://www.readbyqxmd.com/read/28922625/living-and-dying-with-advanced-dementia-a-prospective-cohort-study-of-symptoms-service-use-and-care-at-the-end-of-life
#14
Elizabeth L Sampson, Bridget Candy, Sarah Davis, Anna Buylova Gola, Jane Harrington, Michael King, Nuriye Kupeli, Gerry Leavey, Kirsten Moore, Irwin Nazareth, Rumana Z Omar, Victoria Vickerstaff, Louise Jones
BACKGROUND: Increasing number of people are dying with advanced dementia. Comfort and quality of life are key goals of care. AIMS: To describe (1) physical and psychological symptoms, (2) health and social care service utilisation and (3) care at end of life in people with advanced dementia. DESIGN: 9-month prospective cohort study. SETTING AND PARTICIPANTS: Greater London, England, people with advanced dementia (Functional Assessment Staging Scale 6e and above) from 14 nursing homes or their own homes...
August 1, 2017: Palliative Medicine
https://www.readbyqxmd.com/read/28922588/persistent-negative-symptoms-in-first-episode-psychosis-early-cognitive-and-social-functioning-correlates-and-differences-between-early-and-adult-onset
#15
Olga Puig, Immaculada Baeza, Elena de la Serna, Bibiana Cabrera, Gisela Mezquida, Miquel Bioque, Antonio Lobo, Ana González-Pinto, Mara Parellada, Iluminada Corripio, Eduard Vieta, Julio Bobes, Judith Usall, Fernando Contreras, Manuel J Cuesta, Miquel Bernardo, Josefina Castro-Fornieles, The PEPs Group
OBJECTIVE: To characterize the early cognitive and social functioning characteristics of a sample of first-episode psychosis patients with and without persistent negative symptoms (PNS) and to examine the prevalence and cognitive and functional correlates of PNS in patients with early-onset versus adult-onset first-episode psychosis. METHODS: Participants were 235 patients with first-episode psychosis (51 early-onset, 184 adult-onset) and 240 healthy controls from a multicenter longitudinal study (recruited between 2009 and 2011)...
September 12, 2017: Journal of Clinical Psychiatry
https://www.readbyqxmd.com/read/28922167/statins-and-cognition-in-parkinson-s-disease
#16
Benjamin L Deck, Jacqueline Rick, Sharon X Xie, Alice Chen-Plotkin, John E Duda, James F Morley, Lana M Chahine, Nabila Dahodwala, John Q Trojanowski, Daniel Weintraub
The relationship between statins and cognition in Parkinson's disease (PD) is poorly understood. Analyses were performed to determine associations between statin use and cross-sectional and longitudinal cognitive performance in PD. Neuropsychological tests, medication logs, and ratings of functional abilities were collected from 313 PD participants longitudinally. At baseline, statin users (SU; N = 129) were older, more likely male, and had shorter PD duration than non-statin users (NSU; N = 184). In Cross-sectional analysis, SU performed better on global cognition, Trails B, semantic fluency, and phonemic fluency tasks...
September 11, 2017: Journal of Parkinson's Disease
https://www.readbyqxmd.com/read/28922153/sex-dependent-associations-of-serum-uric-acid-with-brain-function-during-aging
#17
Alexandra M Kueider, Yang An, Toshiko Tanaka, Melissa H Kitner-Triolo, Stephanie Studenski, Luigi Ferrucci, Madhav Thambisetty
Serum uric acid (SUA) is an abundant natural antioxidant which could reduce the burden of cellular oxidation, a major cause of neurodegenerative disease. In line with this, SUA levels are lower in those with Alzheimer's disease; however, the association between SUA and cognition remains unclear. Results from studies examining the effects of SUA on cognition may be difficult to interpret in the context of normal versus pathological aging. This study examined sex-specific associations of baseline SUA with cognition during aging...
September 8, 2017: Journal of Alzheimer's Disease: JAD
https://www.readbyqxmd.com/read/28921167/brain-structural-concomitants-of-resting-state-heart-rate-variability-in-the-young-and-old-evidence-from-two-independent-samples
#18
Hyun Joo Yoo, Julian F Thayer, Steven Greening, Tae-Ho Lee, Allison Ponzio, Jungwon Min, Michiko Sakaki, Lin Nga, Mara Mather, Julian Koenig
Previous research has shown associations between brain structure and resting state high-frequency heart rate variability (HF HRV). Age affects both brain structure and HF HRV. Therefore, we sought to examine the relationship between brain structure and HF HRV as a function of age. Data from two independent studies were used for the present analysis. Study 1 included 19 older adults (10 males, age range 62-78 years) and 19 younger adults (12 males, age range 19-37). Study 2 included 23 older adults (12 males; age range 55-75) and 27 younger adults (17 males; age range 18-34)...
September 18, 2017: Brain Structure & Function
https://www.readbyqxmd.com/read/28919571/reasons-why-children-and-adolescents-with-adhd-stop-and-restart-taking-medicine
#19
William B Brinkman, John O Simon, Jeffery N Epstein
OBJECTIVE: To describe the prevalence of reasons why children and adolescents stop and restart attention-deficit/hyperactivity disorder (ADHD) medicine and whether functional impairment is present after stopping medicine. METHODS: We used the prospective longitudinal cohort from the Multimodal Treatment of Study of Children with ADHD. At the 12 year follow-up when participants were a mean of 21.1 years old, 372 participants (76% male, 64% Caucasian) reported ever taking ADHD medicine...
September 12, 2017: Academic Pediatrics
https://www.readbyqxmd.com/read/28919495/physical-exercise-and-cognitive-function-across-the-life-span-results-of-a-nationwide-population-based-study
#20
Beate Gaertner, Amanda K Buttery, Jonas D Finger, Steffen Wolfsgruber, Michael Wagner, Markus A Busch
OBJECTIVES: To examine cross-sectional and longitudinal associations between physical exercise and cognitive function across different age groups in a nationwide population-based sample of adults aged 18-79 years in Germany. DESIGN: Cross-sectional/prospective. METHODS: Cognitive function was assessed in the mental health module of the German Health Interview and Examination Survey for Adults (DEGS1-MH, 2009-2012, n=3535), using a comprehensive neuropsychological test battery...
September 14, 2017: Journal of Science and Medicine in Sport
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