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Low frequency

Seiichiro Amemiya, A David Redish
During decision making, hippocampal activity encodes information sometimes about present and sometimes about potential future plans. The mechanisms underlying this transition remain unknown. Building on the evidence that gamma oscillations at different frequencies (low gamma [LG], 30-55 Hz; high gamma [HG], 60-90 Hz; and epsilon, 100-140 Hz) reflect inputs from different circuits, we identified how changes in those frequencies reflect different information-processing states. Using a unique noradrenergic manipulation by clonidine, which shifted both neural representations and gamma states, we found that future representations depended on gamma components...
March 20, 2018: Cell Reports
Rose Mary Ferreira Lisboa da Silva, Carlos Eduardo de Souza Miranda, Maira Tonidandel Barbosa, Maria Aparecida Camargos Bicalho
BACKGROUND: The prevalence of orthostatic hypotension (OH) increases with age and is associated with changes in autonomic regulation of blood pressure (BP) and heart rate (HR). OBJECTIVE: to assess HR and HR variability (HRV) in elderly subjects with OH and determine OH predictors. METHODS: a total of 105 patients aged ≥ 60 years, 39 with OH (case group) and 66 without OH (control group) (age-matched) were studied. Patients underwent clinical assessment, electrocardiogram, biochemistry tests and Holter monitoring for spectral analysis of HRV (Fourier transform) in the supine and orthostatism positions to identify low frequency (LF) and high frequency (HF) components, as well as the LF/HF ratio...
March 19, 2018: Arquivos Brasileiros de Cardiologia
Jian Zeng, Dorian Garrick, Jack Dekkers, Rohan Fernando
Genomic prediction exploits single nucleotide polymorphisms (SNPs) across the whole genome for predicting genetic merit of selection candidates. In most models for genomic prediction, e.g. BayesA, B, C, R and GBLUP, independence of SNP effects is assumed. However, SNP effects are expected to be locally dependent given the presence of a nearby QTL because SNPs surrounding the QTL do not segregate independently. A consequence of ignoring this dependence is that SNPs with small effects may be overly shrunk, e...
2018: PloS One
Haw-Tyng Huang, Li Zhu, Matthew D Ward, Brian L Chaloux, Rostislav Hrubiak, Albert Epshteyn, John V Badding, Timothy A Strobel
The chemical stability of solid cubane under high-pressure was examined with in situ Raman spectroscopy and synchrotron powder X-ray diffraction (PXRD) in a diamond anvil cell (DAC) up to 60 GPa. The Raman modes associated with solid cubane were assigned by comparing experimental data with calculations based on density functional perturbation theory, and low-frequency lattice modes are reported for the first time. The equation of state of solid cubane derived from the PXRD measurements taken during compression gives a bulk modulus of 14...
March 21, 2018: Journal of Physical Chemistry Letters
Peter Lewis, Abinaya Priya Venkataraman, Linda Lundström
SIGNIFICANCE: In the field of visual rehabilitation of patients with central visual field loss (CFL), knowledge on how peripheral visual function can be improved is essential. This study presents measurements of peripheral dynamic contrast sensitivity (with optical correction) for off-axis viewing angles in subjects with CFL. PURPOSE: Subjects with CFL rely on a peripheral preferred retinal locus (PRL) for many visual tasks. It is therefore important to ascertain that contrast sensitivity (CS) is maximized in the PRL...
March 21, 2018: Optometry and Vision Science: Official Publication of the American Academy of Optometry
Ivo J Kruyt, Rik C Nelissen, Emmanuel A M Mylanus, Myrthe K S Hol
OBJECTIVE: To compare 3-year implant stability, survival, and tolerability of a 4.5-mm-wide (test) and a 3.75-mm-wide (control) percutaneous titanium implant for bone-conduction hearing, loaded with the sound processor after 3 weeks. METHODS: Sixty implants were allocated in a 2:1 ratio (test-control) in 57 adult patients included in this prospective randomized controlled clinical trial. Follow-up visits were performed at 7, 14, 21, and 28 days; 6 and 12 weeks; 6 months; and at 1, 2, and 3 years after implantation...
March 20, 2018: Otology & Neurotology
Yimy Amarillo, Angela Isabel Tissone, German Mato, Marcela S Nadal
Slow repetitive burst firing by hyperpolarized thalamocortical (TC) neurons correlates with global slow rhythms (< 4 Hz), which are the physiological oscillations during N-REM sleep, or pathological ones during idiopathic epilepsy. The pacemaker activity of TC neurons depends on the expression of several subthreshold conductances, which are modulated in a behaviorally dependent manner. Here we show that up-regulation of the small and neglected inward rectifier potassium current IKir induces repetitive burst firing at slow and delta frequency bands...
March 21, 2018: Journal of Neurophysiology
Seth Wiener, Kiwako Ito, Shari R Speer
This study examines the perceptual trade-off between knowledge of a language's statistical regularities and reliance on the acoustic signal during L2 spoken word recognition. We test how early learners track and make use of segmental and suprasegmental cues and their relative frequencies during non-native word recognition. English learners of Mandarin were taught an artificial tonal language in which a tone's informativeness for word identification varied according to neighborhood density. The stimuli mimicked Mandarin's uneven distribution of syllable+tone combinations by varying syllable frequency and the probability of particular tones co-occurring with a particular syllable...
March 1, 2018: Language and Speech
Tai-Wan Yao, Jia Liu, Xue-Zhi Li, Lin Ma, Jia-Peng Wu, Xiao-Fang Xi, Yan Fu
OBJECTIVE: To assess the effect of electroacupuncture (EA) on chronic inflammatory response of Leydig cells in aged rats with low testosterone, so as to investigate its underlying mechanism of anti-male reproductive aging. METHODS: Twenty-four 20 months old SD rats were randomly divided into EA, medication and aged control groups ( n = 8 in each), and other 8 young SD rats (2 months of age) were used as the youth control group. EA (2 Hz/100 Hz, 1 mA) was applied to "Guanyuan"(CV 4) and bilate-ral "Shenshu"(BL 23) for 15 min, once daily for 8 weeks except the weekends...
March 25, 2018: Zhen Ci Yan Jiu, Acupuncture Research
Ina Bähr, Janine Jahn, Alexander Zipprich, Inge Pahlow, Julia Spielmann, Heike Kielstein
Obesity is associated with alterations in functionality of immune cells, like macrophages and natural killer (NK) cells, leading to an increased risk for severe infections and several cancer types. This study aimed to examine immune cell populations and functional NK cell parameters focusing on NK cell subset phenotypes in normal-weight and obese humans. Therefore, peripheral blood mononuclear cells (PBMCs) were isolated from normal-weight and obese individuals and analyzed by flow cytometry. Results show no significant changes in the frequency of monocytes, B lymphocytes, or NKT cells but a significantly increased frequency of T lymphocytes in obesity...
March 20, 2018: Immunologic Research
Digvijayini Bundhun, Sillma Rampadarath, Daneshwar Puchooa, Rajesh Jeewon
The purpose of the study was to explore the dietary intake, fruit, vegetable and energy intake and lifestyle behaviors among Mauritian children. A validated questionnaire was used, assessing dietary intake, mean energy intake, mean body mass index (BMI), lifestyle behaviors as well as nutritional knowledge (NK) among males and females. 336 children aged 6-12 years (165 males and 171 females) from 8 public primary schools were recruited. Statistical analyses revealed that children consumed less nutritious foods such as fruits, vegetables and whole grains and more of refined and calorie-laden foods, with no significant differences across genders...
February 2018: Heliyon
Quang Hung Trinh, Md Mokter Hossain, Seong H Kim, Young Sun Mok
A double dielectric barrier discharge reactor operated at a low power frequency of 400 Hz and atmospheric pressure was utilized for regulating the wettability of glass surface. The hydrophobic treatment was performed by plasma polymerization of tetramethylsilane (TMS, in argon gas). The obtained results showed that the TMS coatings formed on the glass substrates without oxygen addition were smooth, uniform films with the maximum water contact angle (WCA) of about 106°, which were similar to those obtained by low pressure, high power frequency plasmas reported in the literature...
January 2018: Heliyon
Samar Zaki, Asma Usman, Swaleha Tariq, Sameena Shah, Iqbal Azam, Waris Qidwai, Kashmira Nanji
Objective The goal of this study was to determine the frequency and factors associated with adult immunization in patients visiting family medicine clinics at a tertiary care hospital in Karachi. Methods A cross-sectional study was conducted from March 2014 to March 2015 in a tertiary care hospital in Karachi, Pakistan. Participants more than 18 years were invited to participate in the study. A pretested questionnaire was used to collect information. Data were entered and analyzed using IBM SPSS Statistics for Windows, version 19...
January 17, 2018: Curēus
Ashley Haubert, Matt Walsh, Rachel Boyd, Megan Morris, Megan Wiedbusch, Mike Krusmark, Glenn Gunzelmann
Cognitive fatigue emerges in wide-ranging tasks and domains, but traditional vigilance tasks provide a well-studied context in which to explore the mechanisms underlying it. Though a variety of experimental methodologies have been used to investigate cognitive fatigue in vigilance, relatively little research has utilized electroencephalography (EEG), specifically event-related potentials (ERPs), to explore the nature of cognitive fatigue, also known as the vigilance decrement. Moreover, much of the research that has been done on vigilance and ERPs uses non-traditional vigilance paradigms, limiting generalizability to the established body of behavioral results and corresponding theories...
2018: Frontiers in Psychology
Jörg Encke, Werner Hemmert
The mammalian auditory system is able to extract temporal and spectral features from sound signals at the two ears. One important cue for localization of low-frequency sound sources in the horizontal plane are inter-aural time differences (ITDs) which are first analyzed in the medial superior olive (MSO) in the brainstem. Neural recordings of ITD tuning curves at various stages along the auditory pathway suggest that ITDs in the mammalian brainstem are not represented in form of a Jeffress-type place code. An alternative is the hemispheric opponent-channel code, according to which ITDs are encoded as the difference in the responses of the MSO nuclei in the two hemispheres...
2018: Frontiers in Neuroscience
Megan A Stryker, Raunak D Patel, Dunia T Khaled, Amanda F Saltzman, Jeremy Konheim, Danica May, Allison Feibus, Joseph Fougerousse, Ashley Richman, William Chastant, Samantha Prats, Brian Baksa, Melissa M Montgomery
Background: Proper instruction during medical training regarding performing adequate physical examinations prior to urologic consultations greatly improves patient care. We evaluated the frequency of genitourinary (GU) physical examinations performed prior to urologic consultation to determine the influence of factors affecting the completion of these examinations. Methods: Between January 2013 and December 2014, 1,596 consultations were requested by primary providers and completed by the urology department at a major tertiary care teaching institution...
2018: Ochsner Journal
Jordi Castellsague, Josephina G Kuiper, Anton Pottegård, Ingegärd Anveden Berglind, Daniel Dedman, Lia Gutierrez, Brian Calingaert, Myrthe Pp van Herk-Sukel, Jesper Hallas, Anders Sundström, Arlene M Gallagher, James A Kaye, Carolina Pardo, Kenneth J Rothman, Susana Perez-Gutthann
Background: There is a concern that topical tacrolimus and pimecrolimus, indicated for second-line treatment of atopic dermatitis, may increase the risk of lymphoma and skin cancer, particularly in children. Objective: The aim of this study was to compare incidence rates (IRs) of lymphoma and skin cancer between new users of topical tacrolimus or pimecrolimus and users of moderate- to high-potency topical corticosteroids (TCSs) and untreated subjects. Methods: This is a multicenter cohort study with frequency matching by strata of propensity scores in population databases in the Netherlands, Denmark, Sweden, and the UK...
2018: Clinical Epidemiology
Feifei Z Williams, Atul Vats, Thomas Cash, James D Fortenberry
Respiratory failure associated with hematopoietic stem cell transplantation (HSCT) has been considered a contraindication for use of extracorporeal membrane oxygenation (ECMO) at many centers. We describe a child with neuroblastoma and hypoxemic respiratory failure following HSCT who was successfully managed with veno-venous (VV) ECMO. The patient was an 18-month-old female with high-risk neuroblastoma status post tumor resection, chemotherapy, autologous HSCT, and primary site radiation. On day 113 posttransplant while receiving maintenance immunotherapy, she had an acute respiratory decompensation because of rhinovirus, aspiration pneumonia, and capillary leak syndrome...
March 2018: Journal of Extra-corporeal Technology
S E de Graaf, L Faoro, J Burnett, A A Adamyan, A Ya Tzalenchuk, S E Kubatkin, T Lindström, A V Danilov
Noise and decoherence due to spurious two-level systems located at material interfaces are long-standing issues for solid-state quantum devices. Efforts to mitigate the effects of two-level systems have been hampered by a lack of knowledge about their chemical and physical nature. Here, by combining dielectric loss, frequency noise and on-chip electron spin resonance measurements in superconducting resonators, we demonstrate that desorption of surface spins is accompanied by an almost tenfold reduction in the charge-induced frequency noise in the resonators...
March 20, 2018: Nature Communications
Meili Xu, Jie Wu, Chunlian Wang, Jirong Huo, Liang Lü
To investigate the clinicopathological differences in laterally spreading tumor (LST) from the rectum and colon.
 Methods: Clinicopathological records of 198 patients with LST (116 cases in rectum, 82 cases in colon) from the Second Xiangya Hospital of Central South University between January 2012 and January 2017 were evaluated.
 Results: A total of 198 colorectal LST were included. According to the endoscopic classification, nodular mixed type (LST-GM), homogeneous type (LST-GH), flat elevated type(LST-FE) and pseudodepressed type (LST-PD) were 127(64...
February 28, 2018: Zhong Nan da Xue Xue Bao. Yi Xue Ban, Journal of Central South University. Medical Sciences
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