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https://www.readbyqxmd.com/read/29457560/prophylactic-intra-aortic-balloon-counterpulsation-before-surgical-myocardial-revascularization-in-patients-with-acute-myocardial-infarction
#1
Philippe Grieshaber, Tobias Schneider, Lukas Oster, Coskun Orhan, Peter Roth, Bernd Niemann, Andreas Böning
INTRODUCTION: Prophylactic intra-aortic balloon counterpulsation (pIABC) is recommended for high-risk patients undergoing coronary artery bypass grafting (CABG) surgery. Criteria for high-risk patients benefiting from pIABC are unclear. This study aimed to specifically describe the effect of pIABC on outcomes of patients with acute myocardial infarction (AMI) undergoing CABG. METHODS: In 178 of 484 AMI patients (non-ST-segment elevation myocardial infarction [NSTEMI] or ST-segment elevation myocardial infarction [STEMI] ≤5 days before surgery) without cardiogenic shock who underwent CABG between 2008 and 2013, pIABC was initiated preoperatively...
February 1, 2018: Perfusion
https://www.readbyqxmd.com/read/29456690/protective-effects-of-recombinant-human-brain-natriuretic-peptide-in-perioperative-period-during-open-heart-surgery
#2
Yunbin Xu, Yong Li, Weiguo Bao, Shi Qiu
The aim of the present study was to evaluate the protective effects and safety aspects of recombinant human brain natriuretic peptide (rhBNP) on cardiac functions of patients undergoing open-heart surgery during perioperative period. In total, 150 patients undergoing open heart surgery in the Second Hospital of Shandong Universty from August 2015 to July 2016 were randomly divided into control group and observation group each with 75 cases. Patients in control group were treated by routine rehabilitation while patients in the observation group were treated by both the routine rehabilitation and rhBNP...
March 2018: Experimental and Therapeutic Medicine
https://www.readbyqxmd.com/read/29456238/remote-ischemic-postconditioning-ripc-of-the-upper-arm-results-in-protection-from-cardiac-ischemia-reperfusion-injury-following-primary-percutaneous-coronary-intervention-pci-for-acute-st-segment-elevation-myocardial-infarction-stemi
#3
Bangming Cao, Haipeng Wang, Chi Zhang, Ming Xia, Xiangjun Yang
BACKGROUND The aim of this study was to evaluate the role of remote ischemic postconditioning (RIPC) of the upper arm on protection from cardiac ischemia-reperfusion injury following primary percutaneous coronary intervention (PCI) in patients with acute ST-segment elevation myocardial infarction (STEMI). MATERIAL AND METHODS Eighty patients with STEMI were randomized into two groups: primary PCI (N=44) and primary PCI+RIPC (N=36). RIPC consisted of four cycles of 5 minutes of occlusion and five minutes of reperfusion by cuff inflation and deflation of the upper arm, commencing within one minute of the first PCI balloon dilatation...
February 19, 2018: Medical Science Monitor: International Medical Journal of Experimental and Clinical Research
https://www.readbyqxmd.com/read/29455787/cardiovascular-risk-factors-profile-in-patients-with-acute-coronary-syndrome-with-particular-reference-to-left-ventricular-ejection-fraction
#4
Sheeren Khaled, Rajaa Matahen
BACKGROUND: Acute coronary syndrome (ACS) remains a leading cause of death in the United States. Numerous studies have shown that the degree of LV systolic dysfunction is a major if not the most important determinant of long-term outcome in ACS. OBJECTIVES: To identify the most important risk factors and other clinical predictors which might have impact on left ventricular ejection fraction in patients with ACS. RESULTS: The total patients (299) admitted to our center from July, 2015 till December, 2015; with established diagnosis of ACS were classified in to two groups: Group I: 193 patients with impaired LVEF <40% (64...
January 2018: Indian Heart Journal
https://www.readbyqxmd.com/read/29455773/takotsubo-syndrome
#5
REVIEW
Sanjiv Gupta, Madan Mohan Gupta
Takotsubo syndrome is a reversible acute heart failure frequently precipitated by an emotional or physical stress. The clinical presentation resembles acute coronary syndrome. Pathogenesis is complex and may involve brain-heart axis and neuro-hormonal stunning of the myocardium. Coronary angiography reveals normal epicardial arteries with no obstruction or spasm. NT-ProBNP maybe remarkably elevated. Regional wall motion akinesia (RWMA) of left ventricle extends beyond the territory of one coronary artery. Reduced left ventricle ejection fraction (LVEF) and RWMA recover in 6-12 weeks...
January 2018: Indian Heart Journal
https://www.readbyqxmd.com/read/29454138/prognostic-implications-of-early-monomorphic-and-non-monomorphic-tachyarrhythmias-in-patients-discharged-with-acute-coronary-syndrome
#6
Jo-Jo Hai, Ka-Chun Un, Chun-Ka Wong, Ka-Lam Wong, Zhe-Yu Zhang, Pak-Hei Chan, Chu-Pak Lau, Chung-Wah Siu, Hung-Fat Tse
BACKGROUND: The prognostic implication of early ventricular tachycarrhythmias (VT) after acute coronary syndrome (ACS) remains unclear. OBJECTIVE: We sought to investigate the clinical outcomes of early monomorphic and non-monomorphic VT that occur within 48 hours in patients after ACS. METHODS: We retrospectively reviewed the clinical outcomes of 2033 (mean age: 67.0±13.4 years, 73.1% male) consecutive patients who presented with ACS from 2004 to 2015...
February 14, 2018: Heart Rhythm: the Official Journal of the Heart Rhythm Society
https://www.readbyqxmd.com/read/29452808/norepinephrine-exerts-an-inotropic-effect-during-the-early-phase-of-human-septic-shock
#7
O Hamzaoui, M Jozwiak, T Geffriaud, B Sztrymf, D Prat, F Jacobs, X Monnet, P Trouiller, C Richard, J L Teboul
BACKGROUND: We conducted this study to investigate whether norepinephrine increases cardiac contractility when administered during the early phase of septic shock. METHODS: We studied 38 patients with septic shock who had been resuscitated for <3 h and whose mean arterial pressure (MAP) remained <65 mm Hg. Echocardiographic variables were obtained before (T 0 ) and after either initiation or an increase in the dose of a norepinephrine infusion to increase MAP to ≥ 65 mm Hg (T 1 )...
March 2018: British Journal of Anaesthesia
https://www.readbyqxmd.com/read/29451950/intrinsic-changes-of-left-ventricular-function-in-patients-with-beh%C3%A3-et-disease-and-comparison-according-to-systemic-disease-activity
#8
Byung Joo Sun, Jae-Hyeong Park, Su-Jin Yoo, Yunseon Park, Yeon Ju Kim, In Suk Lee, Jinhyun Kim, In Seol Yoo, Seung Cheol Shim, Seong Wook Kang, Jun-Hyung Kim, Jae-Hwan Lee, Si Wan Choi, Jin-Ok Jeong, In-Whan Seong
PURPOSE: Although cardiac manifestation of Behçet disease (BD) has been described in sporadic reports, its timely diagnosis remains difficult. The objective of this study was to describe early cardiac manifestations of BD. We also performed a comprehensive classification of systemic BD activity and compared their cardiac manifestations. METHODS: A prospective screening using speckle tracking echocardiography was performed in 85 patients with BD who had no history of heart disease...
February 16, 2018: Echocardiography
https://www.readbyqxmd.com/read/29447786/high-sensitivity-cardiac-troponin-t-left-ventricular-function-and-outcome-in-non-st-elevation-acute-coronary-syndrome
#9
K M Eggers, T Jernberg, B Lindahl
BACKGROUND: Cardiac troponin (cTn) levels reflect infarct size and depressed left ventricular ejection fraction (LVEF) in patients with non-ST elevation acute coronary syndrome (NSTE-ACS). However, there is very limited information on whether cTn measured with a high-sensitivity (hs) assay would provide incremental prognostic information to the LVEF in NSTE-ACS patients. METHODS: This was a registry-based study (SWEDEHEART registry) investigating 20,652 NSTE-ACS patients with available information on hs-cTnT (highest level recorded during the hospitalization) and the LVEF estimated using echocardiography...
March 2018: American Heart Journal
https://www.readbyqxmd.com/read/29447739/native-t1-and-ecv-of-noninfarcted-myocardium-and-outcome-in-patients-with-coronary-artery-disease
#10
Valentina O Puntmann, Gerry Carr-White, Andrew Jabbour, Chung-Yao Yu, Rolf Gebker, Sebastian Kelle, Andreas Rolf, Sabine Zitzmann, Elif Peker, Tommaso D'Angelo, Faraz Pathan, Elen, Silvia Valbuena, Rocio Hinojar, Christophe Arendt, Jagat Narula, Eva Herrmann, Andreas M Zeiher, Eike Nagel
BACKGROUND: Coronary artery disease (CAD) remains the major cause of cardiac morbidity and mortality worldwide, despite the advances in treatment with coronary revascularization and modern antiremodeling therapy. Risk stratification in CAD patients is primarily based on left ventricular volumes, ejection fraction (LVEF), risk scores, and the presence and extent of late gadolinium enhancement (LGE). The prognostic role of T1 mapping in noninfarcted myocardium in CAD patients has not yet been determined...
February 20, 2018: Journal of the American College of Cardiology
https://www.readbyqxmd.com/read/29446126/layer-specific-global-longitudinal-strain-reveals-impaired-cardiac-function-in-patients-with-reversible-ischemia
#11
Christoffer E Hagemann, Søren Hoffmann, Flemming J Olsen, Peter G Jørgensen, Thomas Fritz-Hansen, Jan S Jensen, Tor Biering-Sørensen
AIMS: Two-dimensional speckle tracking echocardiography (2DSTE) detects early signs of left ventricular dysfunction; however, it is unknown whether layer-specific global longitudinal strain (GLS) has incremental value in diagnosis of patients with reversible ischemia assessed by single photon emission computed tomography (SPECT). METHODS AND RESULTS: Eighty patients with stable angina pectoris (SAP), normal left ventricular ejection fraction (LVEF), and no history of ischemic heart disease were retrospectively identified to have been examined by 2DSTE, SPECT, and coronary angiography (CAG)...
February 15, 2018: Echocardiography
https://www.readbyqxmd.com/read/29440034/subclinical-compromise-in-cardiac-strain-relates-to-lower-cognitive-performances-in-older-adults
#12
Hailey A Kresge, Omair A Khan, Madison A Wagener, Dandan Liu, James G Terry, Sangeeta Nair, Francis E Cambronero, Katherine A Gifford, Katie E Osborn, Timothy J Hohman, Kimberly R Pechman, Susan P Bell, Thomas J Wang, John Jeffrey Carr, Angela L Jefferson
BACKGROUND: Global longitudinal strain (GLS), reflecting total shortening of the myocardium during the cardiac cycle, has emerged as a more precise myocardial function measure than left ventricular ejection fraction (LVEF). Longitudinal strain may be selectively affected in subclinical heart disease, even in the presence of normal LVEF. This study examines subclinical cardiac dysfunction, assessed by GLS and LVEF, and cognition among older adults. METHODS AND RESULTS: Vanderbilt Memory and Aging Project participants who were free of clinical dementia, stroke, and heart failure (n=318, 73±7 years, 58% male) completed neuropsychological assessment and cardiac magnetic resonance to quantify GLS and LVEF...
February 13, 2018: Journal of the American Heart Association
https://www.readbyqxmd.com/read/29439881/prospective-assessment-of-the-frequency-of-low-gradient-severe-aortic-stenosis-with-preserved-left-ventricular-ejection-fraction-critical-impact-of-aortic-flow-misalignment-and-pressure-recovery-phenomenon
#13
Anne Ringle, Anne-Laure Castel, Caroline Le Goffic, François Delelis, Camille Binda, Yohan Bohbot, Pierre Vladimir Ennezat, Raphaëlle A Guerbaai, Franck Levy, André Vincentelli, Pierre Graux, Christophe Tribouilloy, Sylvestre Maréchaux
BACKGROUND: The frequency of paradoxical low-gradient severe aortic stenosis (AS) varies widely across studies. The impact of misalignment of aortic flow and pressure recovery phenomenon on the frequency of low-gradient severe AS with preserved left ventricular ejection fraction (LVEF) has not been evaluated in prospective studies. AIMS: To investigate prospectively the impact of aortic flow misalignment by Doppler and lack of pressure recovery phenomenon correction on the frequency of low-gradient (LG) severe aortic stenosis (AS) with preserved LVEF...
February 10, 2018: Archives of Cardiovascular Diseases
https://www.readbyqxmd.com/read/29438721/changes-in-left-ventricular-systolic-and-diastolic-function-on-serial-echocardiography-after-out-of-hospital-cardiac-arrest
#14
Jacob C Jentzer, Nandan S Anavekar, Sunil V Mankad, Roger D White, Kianoush B Kashani, Gregory W Barsness, Alejandro A Rabinstein, Sorin V Pislaru
AIM: Reversible myocardial dysfunction is common after out-of-hospital cardiac arrest (OHCA). The aim of this study was to determine if changes on serial transthoracic echocardiography (TTE) can predict long-term mortality in OHCA subjects. METHODS: This is a single-center historical cohort study of OHCA subjects undergoing targeted temperature management who received >1 TTE during hospitalization. Two-dimensional and Doppler parameters of systolic and diastolic function were compared between paired TTE...
February 10, 2018: Resuscitation
https://www.readbyqxmd.com/read/29437242/impact-of-procedure-related-conduction-disturbances-after-transcatheter-aortic-valve-implantation-on-myocardial-performance-and-survival-evaluated-by-conventional-and-speckle-tracking-echocardiography
#15
Zisis Dimitriadis, Smita Scholtz, Werner Scholtz, Marcus Wiemer, Cornelia Piper, Stephan Ensminger, Henrik Fox, Dieter Horstkotte, Lothar Faber
OBJECTIVES: Although procedure-related new cardiac conduction disturbances (CCDs) remain an important issue in transcatheter aortic valve implantation (TAVI), their effect on myocardial function and overall patient outcome remains unclear. The goal of this study was to analyze the influence of procedure-related CCDs on systolic and diastolic LV performance and on patient survival after TAVI. METHODS AND RESULTS: Ninety-five patients who underwent TAVI for severe symptomatic aortic stenosis (AS) and had a complete follow-up were evaluated with respect to procedure-related CCDs...
February 13, 2018: Echocardiography
https://www.readbyqxmd.com/read/29434624/improvement-of-increased-cqtd-is-associated-with-heart-function-in-patients-with-ischemic-heart-failure
#16
Hui Guo, Miao Wang, Juan Zhao, Jing Liu, Jie-Mei Yang
Background: Chronic heart failure (CHF) is life-threatening without timely or effective intervention. In this study, we investigated the association between QT dispersion corrected for heart rate (cQTd) and heart function in patients with CHF. Methods: From January 2013 to December 2015, we continuously enrolled 240 patients categorized as New York Heart Association functional class (NYHA) III-IV with a left ventricular ejection fraction (LVEF) < 40%. Based on the etiology, the patients were divided into a dilated cardiomyopathy (DCM) group ( n = 120) and an ischemic cardiomyopathy (ICM) group ( n = 120)...
January 2018: Journal of Geriatric Cardiology: JGC
https://www.readbyqxmd.com/read/29432198/impact-of-image-quality-on-reliability-of-the-measurements-of-left-ventricular-systolic-function-and-global-longitudinal-strain-in-2d-echocardiography
#17
Yasufumi Nagata, Yuichiro Kado, Takeshi Onoue, Kyoko Otani, Akemi Nakazono, Yutaka Otsuji, Masaaki Takeuchi
BACKGROUND: Left ventricular ejection fraction (LVEF) and global longitudinal strain (GLS) play important roles in diagnosis and management of cardiac diseases. However, the issue of the accuracy and reliability of LVEF and GLS remains to be solved. Image quality is one of the most important factors affecting measurement variability. The aim of this study was to investigate whether improved image quality could reduce observer variability. METHODS: Two sets of three apical images were acquired using relatively old- and new-generation ultrasound imaging systems (Vivid 7 and Vivid E95) in 308 subjects...
February 5, 2018: Echo Research and Practice
https://www.readbyqxmd.com/read/29431592/in-season-changes-in-ventricular-morphology-and-systolic-function-in-adolescent-female-athletes
#18
Andrew M Watson, Carol Coutinho, Kristin Haraldsdottir, Stacey Brickson, Warren Dunn, Marlowe Eldridge
PURPOSE: To evaluate the influence of physical maturity on the changes in ventricular morphology and function with sport training in female youth athletes. METHODS: Thirty-two female athletes (age 13-18 years) underwent height and weight measurement and 2-D echocardiographic evaluation immediately prior to, and following, a 20-week soccer season. Pre- and post-season left ventricular end-diastolic diameter (LVEDD), end-diastolic volume (LVEDV), ejection fraction (LVEF), stroke volume (LVSV), mass (LVM), and posterior wall thickness (LVPWT), right ventricular end-diastolic diameter (RVEDD), end-diastolic area (RVEDA), and fractional area change (RVFAC), and interventricular septal thickness (IVST) were compared...
February 12, 2018: European Journal of Sport Science
https://www.readbyqxmd.com/read/29430653/regression-equations-for-calculation-of-z-scores-for-echocardiographic-measurements-of-left-heart-structures-in-healthy-han-chinese-children
#19
Shan-Shan Wang, Wen-Jing Hong, Yu-Qi Zhang, Shu-Bao Chen, Guo-Ying Huang, Hong-Yan Zhang, Li-Jun Chen, Lan-Ping Wu, Rong Shen, Yi-Qing Liu, Jun-Xue Zhu
OBJECTIVE: Clinical decision making in children with heart disease relies on detailed measurements of cardiac structures using two-dimensional and M-mode echocardiography. However, no echocardiographic reference values are available for the Chinese children. We aimed to establish z-score regression equations for left heart structures in a population-based cohort of healthy Chinese Han children. METHOD: Echocardiography was performed in 545 children with a normal heart...
February 12, 2018: Journal of Clinical Ultrasound: JCU
https://www.readbyqxmd.com/read/29429038/pharmacodynamic-modeling-of-cardiac-biomarkers-in-breast-cancer-patients-treated-with-anthracycline-and-trastuzumab-regimens
#20
Aurelia H M de Vries Schultink, Annelies H Boekhout, Jourik A Gietema, Artur M Burylo, Thomas P C Dorlo, J G Coen van Hasselt, Jan H M Schellens, Alwin D R Huitema
Trastuzumab is associated with cardiotoxicity, manifesting as a decrease of the left-ventricular ejection fraction (LVEF). Administration of anthracyclines prior to trastuzumab increases risk of cardiotoxicity. High-sensitive troponin T and N-terminal-pro-brain natriuretic peptide (NT-proBNP) are molecular markers that may allow earlier detection of drug-induced cardiotoxicity. In this analysis we aimed to quantify the kinetics and exposure-response relationships of LVEF, troponin T and NT-proBNP measurements, in patients receiving anthracycline and trastuzumab...
February 10, 2018: Journal of Pharmacokinetics and Pharmacodynamics
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