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https://www.readbyqxmd.com/read/29035606/awareness-perception-and-barriers-to-seeking-information-from-online-academic-databases-and-medical-journals-as-sources-of-information
#1
Li Ping Wong, Sharina Mahavera Mohamad Shakir, Wen Ting Tong, Haridah Alias, Nasrin Aghamohammadi, Kulenthran Arumugam
Medical students' use of online medical journals as a source of information is crucial in the learning pathway to become medical doctors. We conducted a cross-sectional survey study among University medical students between December 2012 and March 2013 to assess their awareness, perceived usefulness, practices, and barriers to seeking information from online academic databases and medical journals. The response rate was 67.53%. The majority of the students knew of the availability of online academic databases and medical journals...
October 16, 2017: Informatics for Health & Social Care
https://www.readbyqxmd.com/read/29028742/intraoperative-esmolol-as-an-adjunct-for-perioperative-opioid-and-postoperative-pain-reduction-a-systematic-review-meta-analysis-and-meta-regression
#2
Amanda M Gelineau, Michael R King, Karim S Ladha, Sara M Burns, Timothy Houle, T Anthony Anderson
BACKGROUND: Esmolol is an ultrashort β-1 receptor antagonist. Recent studies suggest a role for esmolol in pain response modulation. The authors performed a meta-analysis to determine if the intraoperative use of esmolol reduces opioid consumption or pain scores. METHODS: PubMed, Cochrane Database of Systematic Reviews, Cochrane Central Register of Controlled Trials, pubget, and Google Scholar were searched. Studies were included if they were randomized, placebo- or opioid-controlled trials written in English, and performed on patients 18 years of age or older...
October 11, 2017: Anesthesia and Analgesia
https://www.readbyqxmd.com/read/29024361/emotional-processing-in-obesity-a-systematic-review-and-exploratory-meta-analysis
#3
REVIEW
J Fernandes, F Ferreira-Santos, K Miller, S Torres
The role of emotional functioning in the development and maintenance of obesity has been investigated, but the literature is poorly integrated. A systematic review and meta-analysis was performed to explore emotional processing impairments in obesity. PubMed, Web of Knowledge and PsycINFO databases were searched in March 2016, yielding 31 studies comparing emotional processing competencies in individuals with obesity, with or without binge eating disorder (BED), and control groups. Meta-analyses demonstrated that individuals with obesity had higher scores of alexithymia (d = 0...
October 10, 2017: Obesity Reviews: An Official Journal of the International Association for the Study of Obesity
https://www.readbyqxmd.com/read/29024264/deutetrabenazine-for-tardive-dyskinesia-a-systematic-review-of-the-efficacy-and-safety-profile-for-this-newly-approved-novel-medication-what-is-the-number-needed-to-treat-number-needed-to-harm-and-likelihood-to-be-helped-or-harmed
#4
REVIEW
Leslie Citrome
OBJECTIVE: Deutetrabenazine is a deuterated formulation of tetrabenazine. The aim of this systematic review is to describe the efficacy, tolerability and safety of deutetrabenazine for the treatment of tardive dyskinesia (TD). DATA SOURCES: The pivotal registration trials were accessed by querying http://www.ncbi.nlm.nih.gov/pubmed/ and http://www.clinicaltrials.gov, for the search terms 'deutetrabenazine' OR 'SD-809', and by also querying the EMBASE (Elsevier) commercial database for clinical poster abstracts, and by asking the manufacturer for copies of posters presented at congresses...
October 12, 2017: International Journal of Clinical Practice
https://www.readbyqxmd.com/read/28994302/observing-eye-movements-and-the-influence-of-cognition-during-a-symbol-search-task-a-comparison-across-three-age-groups
#5
Maxine Perrin, Manon Robillard, Annie Roy-Charland
This study examined eye movements during a visual search task as well as cognitive abilities within three age groups. The aim was to explore scanning patterns across symbol grids and to better understand the impact of symbol location in AAC displays on speed and accuracy of symbol selection. For the study, 60 students were asked to locate a series of symbols on 16 cell grids. The EyeLink 1000 was used to measure eye movements, accuracy, and response time. Accuracy was high across all cells. Participants had faster response times, longer fixations, and more frequent fixations on symbols located in the middle of the grid...
October 10, 2017: Augmentative and Alternative Communication: AAC
https://www.readbyqxmd.com/read/28994131/systematic-review-and-meta-analysis-assessment-of-factors-affecting-disability-in-inflammatory-bowel-disease-and-the-reliability-of-the-inflammatory-bowel-disease-disability-index
#6
REVIEW
B Lo, M V Prosberg, L L Gluud, W Chan, R W Leong, E van der List, M van der Have, H Sarter, C Gower-Rousseau, L Peyrin-Biroulet, I Vind, J Burisch
BACKGROUND: The Inflammatory Bowel Disease Disability Index (IBD-DI) has recently been developed for patients with Crohn's disease (CD) and ulcerative colitis (UC). AIM: To assess the severity of disability and associated factors using the IBD-DI, and review the validity of the IBD-DI as a tool. METHOD: Systematic review of cross-sectional studies. Patients included had UC or CD and were classified as active, in remission, or needing surgery, biological and/or steroid treatment...
October 9, 2017: Alimentary Pharmacology & Therapeutics
https://www.readbyqxmd.com/read/28988517/developing-and-testing-a-consensus-based-core-set-of-outcome-measures-for-rehabilitation-in-musculoskeletal-diseases
#7
M Klokkerud, H Dagfinrud, T Uhlig, T N Dager, K-A Furunes, Å Klokkeide, M Larsen, S Nygård, S Nylenna, L Øie, I Kjeken
OBJECTIVES: Rehabilitation is important for people with musculoskeletal diseases (MSDs), and evaluating the effect of rehabilitation on both an individual and group level is advocated. A consensus concerning use of outcome measures will improve collaboration between healthcare providers, and increase the possibility of conducting meta-analyses in future research. The aim of this study was to develop a consensus-based core set of outcome measures for rehabilitation in MSDs, and to test the feasibility and responsiveness of the set...
October 9, 2017: Scandinavian Journal of Rheumatology
https://www.readbyqxmd.com/read/28982347/outcome-measures-for-oral-health-based-on-clinical-assessments-and-claims-data-feasibility-evaluation-in-practice
#8
Riët Hummel, Josef Bruers, Onno van der Galiën, Wil van der Sanden, Geert van der Heijden
BACKGROUND: It is well known that treatment variation exists in oral healthcare, but the consequences for oral health are unknown as the development of outcome measures is still in its infancy. The aim of this study was to identify and develop outcome measures for oral health and explore their performance using health insurance claims records and clinical data from general dental practices. METHODS: The Dutch healthcare insurance company Achmea collaborated with researchers, oral health experts, and general dental practitioners (GDPs) in a proof of practice study to test the feasibility of measures in general dental practices...
October 5, 2017: BMC Oral Health
https://www.readbyqxmd.com/read/28982121/short-term-efficacy-and-tolerability-of-venlafaxine-extended-release-in-adults-with-generalized-anxiety-disorder-without-depression-a-meta-analysis
#9
Xinyuan Li, Lijun Zhu, Yingying Su, Shaokuan Fang
BACKGROUND: Although efficacy of venlafaxine extended release (XR) for generalized anxiety disorder (GAD) has been reported in previous analyses in 2002 and 2004, the sample size was rather small and estimate of safety or tolerability was not clear. The present analysis had the advantage of large sample size and provided evidence for tolerability. METHODS: Literature databases were searched, including Pubmed, Embase, Cochrane Central Register of Controlled Trials, Web of science and clinical trials...
2017: PloS One
https://www.readbyqxmd.com/read/28973626/delirium-in-older-persons-advances-in-diagnosis-and-treatment
#10
REVIEW
Esther S Oh, Tamara G Fong, Tammy T Hshieh, Sharon K Inouye
Importance: Delirium is defined as an acute disorder of attention and cognition. It is a common, serious, and often fatal condition among older patients. Although often underrecognized, delirium has serious adverse effects on the individual's function and quality of life, as well as broad societal effects with substantial health care costs. Objective: To summarize the current state of the art in diagnosis and treatment of delirium and to highlight critical areas for future research to advance the field...
September 26, 2017: JAMA: the Journal of the American Medical Association
https://www.readbyqxmd.com/read/28967695/intravenous-immunoglobulin-for-the-treatment-of-childhood-encephalitis
#11
REVIEW
Mildred A Iro, Natalie G Martin, Michael Absoud, Andrew J Pollard
BACKGROUND: Encephalitis is a syndrome of neurological dysfunction due to inflammation of the brain parenchyma, caused by an infection or an exaggerated host immune response, or both. Attenuation of brain inflammation through modulation of the immune response could improve patient outcomes. Biological agents such as immunoglobulin that have both anti-inflammatory and immunomodulatory properties may therefore be useful as adjunctive therapies for people with encephalitis. OBJECTIVES: To assess the efficacy and safety of intravenous immunoglobulin (IVIG) as add-on treatment for children with encephalitis...
October 2, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/28959220/stress-related-mental-health-symptoms-in-coast-guard-incidence-vulnerability-and-neurocognitive-performance
#12
Richard J Servatius, Justin D Handy, Michael J Doria, Catherine E Myers, Christine E Marx, Robert Lipsky, Nora Ko, Pelin Avcu, W Geoffrey Wright, Jack W Tsao
U.S. Coast Guard (CG) personnel face occupational stressors (e.g., search and rescue) which compound daily life stressors encountered by civilians. However, the degree CG personnel express stress-related mental health symptoms of posttraumatic stress disorder (PTSD) and major depressive disorder (MDD) is understudied as a military branch, and little is known concerning the interplay of vulnerabilities and neurocognitive outcomes in CG personnel. The current study addressed this knowledge gap, recruiting 241 active duty CG personnel (22% female) to assess mental health, personality, and neurocognitive function...
2017: Frontiers in Psychology
https://www.readbyqxmd.com/read/28956944/should-we-stop-thinking-about-inhibition-searching-for-individual-and-age-differences-in-inhibition-ability
#13
Alodie Rey-Mermet, Miriam Gade, Klaus Oberauer
Inhibition is often conceptualized as a unitary construct reflecting the ability to ignore and suppress irrelevant information. At the same time, it has been subdivided into inhibition of prepotent responses (i.e., the ability to stop dominant responses) and resistance to distracter interference (i.e., the ability to ignore distracting information). The present study investigated the unity and diversity of inhibition as a psychometric construct, and tested the hypothesis of an inhibition deficit in older age...
September 28, 2017: Journal of Experimental Psychology. Learning, Memory, and Cognition
https://www.readbyqxmd.com/read/28955778/a-novel-dual-luciferase-based-high-throughput-assay-to-monitor-autophagy-in-real-time-in-yeast-s-cerevisiae
#14
Piyush Mishra, Shashank Rai, Ravi Manjithaya
BACKGROUND: Macroautophagy is a cellular response to starvation wherein superfluous and damaged cytoplasmic constituents are degraded to provide energy for survival and to maintain cellular homeostasis. Dysfunctional autophagy is attributed to disease progression in several pathological conditions and therefore, autophagy has appeared as a potential pharmacological target for such conditions. OBJECTIVE: In search of potential drugs that modulate autophagy, identifying small molecule effectors of autophagy is the primary step...
September 2017: Biochemistry and Biophysics Reports
https://www.readbyqxmd.com/read/28953508/impact-of-regional-anesthesia-on-recurrence-metastasis-and-immune-response-in-breast-cancer-surgery-a-systematic-review-of-the-literature
#15
Oscar Pérez-González, Luis F Cuéllar-Guzmán, José Soliz, Juan P Cata
BACKGROUND AND OBJECTIVES: The perioperative period is critical in the long-term prognosis of breast cancer patients. The use of regional anesthesia, such as paravertebral block (PVB), could be associated with improvements in long-term survival after breast cancer surgery by modulating the inflammatory and immune response associated with the surgical trauma, reducing opioid and general anesthetic consumption, and promoting cancer cells death by a direct effect of local anesthetics. METHODS: A systematic literature search was conducted for studies of patients who received PVB for breast cancer surgery...
September 27, 2017: Regional Anesthesia and Pain Medicine
https://www.readbyqxmd.com/read/28950246/towards-reporting-standards-for-neuropsychological-study-results-a-proposal-to-minimize-communication-errors-with-standardized-qualitative-descriptors-for-normalized-test-scores
#16
Mike R Schoenberg, Ruba S Rum
OBJECTIVE: Rapid, clear and efficient communication of neuropsychological results is essential to benefit patient care. Errors in communication are a lead cause of medical errors; nevertheless, there remains a lack of consistency in how neuropsychological scores are communicated. A major limitation in the communication of neuropsychological results is the inconsistent use of qualitative descriptors for standardized test scores and the use of vague terminology. PATIENTS AND METHODS: PubMed search from 1 Jan 2007 to 1 Aug 2016 to identify guidelines or consensus statements for the description and reporting of qualitative terms to communicate neuropsychological test scores was conducted...
July 25, 2017: Clinical Neurology and Neurosurgery
https://www.readbyqxmd.com/read/28942855/a-systematic-review-and-meta-analysis-of-factors-for-delirium-in-vascular-surgical-patients
#17
REVIEW
Christopher Oldroyd, Anna F M Scholz, Robert J Hinchliffe, Kathryn McCarthy, Jonathan Hewitt, Terrence J Quinn
BACKGROUND: Delirium is a common syndrome responsible for a large burden of morbidity and mortality. In surgical settings, research into risk factors for postoperative delirium has largely focused on elective orthopedic patients. We performed a systematic review and meta-analysis to evaluate the evidence surrounding risk factors for delirium in vascular surgical populations. METHODS: Two independent reviewers searched five databases (MEDLINE, Web of Science, Embase, Cumulative Index to Nursing and Allied Health Literature, and PsycINFO) from January 1987 to December 2015...
October 2017: Journal of Vascular Surgery
https://www.readbyqxmd.com/read/28938670/statins-and-the-risk-of-cirrhosis-in-hepatitis-b-or-c-patients-a-systematic-review-and-dose-response-meta-analysis-of-observational-studies
#18
Yaqin Wang, Jianping Xiong, Meng Niu, Xiaowei Chen, Long Gao, Qirun Wu, Kechuang Zheng, Ke Xu
Hepatitis B and hepatitis C are leading causes of chronic liver disease, particularly cirrhosis. Recently, several studies have observed that statins have an inverse relationship with cirrhosis in hepatitis B or C patients. However, no published meta-analysis studied the protective effect of statins on cirrhosis. Thus, we conducted a systematic review and meta-analysis of published observational studies to better understand the relationship between statins and the risk of cirrhosis. Relevant studies were identified by searching PubMed, EMBASE, and ISI Web of Science for articles published before April 2017...
August 29, 2017: Oncotarget
https://www.readbyqxmd.com/read/28937500/serum-adiponectin-levels-in-patients-with-systemic-lupus-erythematosus-a-meta-analysis
#19
Ahmed Ali Dini, Peng Wang, Dong-Qing Ye
BACKGROUND: Higher serum adiponectin in systemic lupus erythematosus (SLE) patients mitigates the inflammatory response. Previous studies investigated serum adiponectin level in SLE patients compared with control subjects, yielding inconsistent results. OBJECTIVE: The aim of this meta-analysis was to assess the difference between serum adiponectin levels in SLE patients compared with control subjects. METHODS: MEDLINE, PubMed, EMBASE, and Web of Science were searched from inception to August 31, 2016, to identify all observational studies that examined the relationship between serum adiponectin levels and SLE...
September 21, 2017: Journal of Clinical Rheumatology: Practical Reports on Rheumatic & Musculoskeletal Diseases
https://www.readbyqxmd.com/read/28937471/serum-adiponectin-levels-in-patients-with-systemic-lupus-erythematosus-a-meta-analysis
#20
Ahmed Ali Dini, Peng Wang, Dong-Qing Ye
BACKGROUND: Higher serum adiponectin in systemic lupus erythematosus (SLE) patients mitigates the inflammatory response. Previous studies investigated serum adiponectin level in SLE patients compared with control subjects, yielding inconsistent results. OBJECTIVE: The aim of this meta-analysis was to assess the difference between serum adiponectin levels in SLE patients compared with control subjects. METHODS: MEDLINE, PubMed, EMBASE, and Web of Science were searched from inception to August 31, 2016, to identify all observational studies that examined the relationship between serum adiponectin levels and SLE...
October 2017: Journal of Clinical Rheumatology: Practical Reports on Rheumatic & Musculoskeletal Diseases
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