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https://www.readbyqxmd.com/read/28729947/associations-between-optic-nerve-head-related-anatomical-parameters-and-refractive-error-over-the-full-range-of-glaucoma-severity
#1
Neda Baniasadi, Mengyu Wang, Hui Wang, Mufeed Mahd, Tobias Elze
PURPOSE: To evaluate the associations between optic disc (OD)-related anatomical parameters (interartery angle [IAA] between superior and inferior temporal retinal arteries, OD tilt [TL], rotation [ROT], and torsion [TO], OD surface curvature [CUR], and central retinal vessel trunk entry point location [CRVTL] on OD) and the spherical equivalent of refractive error (SE), and to assess the impact of glaucoma severity on these relationships. METHODS: Cirrus optical coherence tomography (OCT) fundus images and 24-2 visual fields of 438 patients were included...
July 2017: Translational Vision Science & Technology
https://www.readbyqxmd.com/read/28729396/acute-volume-loading-exacerbates-direct-ventricular-interaction-in-a-model-of-copd
#2
William Spencer Cheyne, Alexandra Mackenzie Williams, Megan I Harper, Neil Derek Eves
Volume loading increases left ventricular (LV) stroke volume (LVSV) through series interaction but may paradoxically reduce LVSV in the presence of large increases in right ventricular (RV) afterload due to direct ventricular interaction (DVI). RV afterload is often increased in COPD as a result of pathological changes to respiratory mechanics, namely increased negative intrathoracic pressure (nITP), dynamic lung hyperinflation (DH) and increased pulmonary vascular resistance (PVR). These hallmarks of COPD negatively impact LV hemodynamics in normovolemia...
July 20, 2017: Journal of Applied Physiology
https://www.readbyqxmd.com/read/28727959/is-psychology-headed-in-the-right-direction
#3
Ethan Kross
Is psychology headed in the right direction? In this essay, I share my views on the answer to this question. I begin by describing how recent advances in technology, heightened levels of interdisciplinary collaboration, a renewed emphasis on considering the broader implications of basic psychological research, and field-wide efforts to encourage optimal research practices have combined to tilt psychology's trajectory upward. I then offer three suggestions for how to maintain the field's upward slanting course: (a) collaborate more to build cumulative knowledge, (b) improve the way we communicate contextual factors in psychological research, and (c) examine the psychological effects of technology...
July 2017: Perspectives on Psychological Science: a Journal of the Association for Psychological Science
https://www.readbyqxmd.com/read/28727900/head-midline-position-for-preventing-the-occurrence-or-extension-of-germinal-matrix-intraventricular-hemorrhage-in-preterm-infants
#4
REVIEW
Olga Romantsik, Maria Grazia Calevo, Matteo Bruschettini
BACKGROUND: Preterm birth is known to constitute the major risk factor for development of germinal matrix-intraventricular hemorrhage (GM-IVH). Head position may affect cerebral hemodynamics and thus may be involved indirectly in development of GM-IVH. Turning the head toward one side may functionally occlude jugular venous drainage on the ipsilateral side while increasing intracranial pressure and cerebral blood volume. Thus, it has been suggested that cerebral venous pressure is reduced and hydrostatic brain drainage improved if the patient is in supine midline position with the bed tilted 30°...
July 20, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/28720881/patients-with-orthostatic-intolerance-relationship-to-autonomic-function-tests-results-and-reproducibility-of-symptoms-on-tilt
#5
Hyung Lee, Phillip A Low, Hyun Ah Kim
This study was designed to investigate the frequency and pattern of orthostatic symptoms during head-up tilt (HUT) in patients with orthostatic intolerance during daily life, and to identify the relationship between the orthostatic symptoms during HUT and autonomic parameters. We prospectively collected autonomic data from 464 patients with orthostatic symptoms. Adrenergic and cardiovagal function tests including HUT were performed. Based on HUT results, we divided patients into orthostatic hypotension (OH), postural tachycardia syndrome (POTS), or normal HUT groups...
July 18, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28717991/prolonged-bed-rest-impairs-rapid-cpi-17-phosphorylation-and-contraction-in-rat-mesenteric-resistance-arteries-to-cause-orthostatic-hypotension
#6
Toshio Kitazawa, Kazuyo Kitazawa
Prolonged bed rest (PBR) causes orthostatic hypotension (OH). Rapid constriction of splanchnic resistance arteries in response to a sudden increase in sympathetic tone contributes to the recovery of orthostatic arterial pressure upon standing. However, the molecular mechanism of PBR-induced dysfunction in arterial constriction is not fully understood. Previously, we showed that CPI-17, a regulatory protein for myosin phosphatase, mediates α1A-adrenergic receptor-induced rapid contraction of small mesenteric arteries...
July 17, 2017: Pflügers Archiv: European Journal of Physiology
https://www.readbyqxmd.com/read/28717604/central-vestibular-syndrome-in-a-red-fox-vulpes-vulpes-with-presumptive-right-caudal-cerebral-artery-ischemic-infarct-and-prevalent-midbrain-involvement
#7
Mario Ricciardi, Floriana Gernone, Antonio De Simone, Pasquale Giannuzzi
A wild young male red fox (Vulpes vulpes) was found in the mountainous hinterland of Rome (Italy) with a heavily depressed mental status and unresponsive to the surrounding environment. Neurological examination revealed depression, left circling, right head tilt, ventromedial positional strabismus and decreased postural reactions on the left side. Neurological abnormalities were suggestive of central vestibular syndrome. Two consecutive MRIs performed with 30 days interval were compatible with lacunar ischemic infarct in the territory of right caudal cerebral artery and its collateral branches...
2017: Open veterinary journal
https://www.readbyqxmd.com/read/28717053/pure-autonomic-failure
#8
REVIEW
Thomas P Brown
Pure autonomic failure is a degenerative disorder of the peripheral autonomic nervous system. Patients experience symptomatic hypotension that requires them to sit, squat or lie down to prevent syncope. It is associated with characteristic histopathological findings, resulting in neuronal cytoplasmic inclusions in the peripheral autonomic nerves. These lesions are responsible for defects in the synthesis and release of norepinephrine from sympathetic nerve terminals, resulting in significant hypotension. Patients with autonomic failure also have exaggerated blood pressure responses to common stimuli such as food or fluid intake, heat, exercise and medications...
July 17, 2017: Practical Neurology
https://www.readbyqxmd.com/read/28713055/anterior-and-nasal-transposition-of-inferior-oblique-muscle-in-cases-of-superior-oblique-palsy
#9
Rohit Saxena, Medha Sharma, Digvijay Singh, Pradeep Sharma
PURPOSE: To report long-term outcome of inferior oblique anterior and nasal transposition in superior oblique palsy. METHODS: The medical records of patients with superior oblique palsy who underwent inferior oblique anterior nasal transposition were reviewed retrospectively. A comprehensive ophthalmic evaluation, including prism bar cover test and measurement of torsion, was performed for all cases. One-year postoperative results were evaluated for alignment in primary gaze, contralateral gaze, and upgaze; reduction in inferior oblique overaction and changes in fundus torsion to assess long-term outcome of the procedure...
July 13, 2017: Journal of AAPOS: the Official Publication of the American Association for Pediatric Ophthalmology and Strabismus
https://www.readbyqxmd.com/read/28712801/the-effect-of-pelvic-tilt-and-femoral-head-size-on-hip-range-of-motion-to-impingement
#10
Thomas F McCarthy, Jim Nevelos, Randa K Elmallah, Morad Chughtai, Anton Khlopas, Vincent Alipit, Timothy C Wagner, Michael A Mont
BACKGROUND: About 50%-70% of dislocators have cups placed within so-called "safe zones." It has been postulated that factors such as femoral head size and pelvic tilt, obliquity, or rotation may influence postoperative stability. Therefore, we assessed varying degrees of pelvic tilt and head sizes on the range of motion (ROM) to impingement. METHODS: A hip simulator was used to import models of 10 subjects who performed object pickup, squatting, and low-chair rising...
June 15, 2017: Journal of Arthroplasty
https://www.readbyqxmd.com/read/28704683/visual-targeting-one-step-before-force-plates-has-no-effect-on-gait-parameters-in-orthopaedic-patients-during-level-walking
#11
Katrin Bracht-Schweizer, Marie Freslier, Sebastian Krapf, Jacqueline Romkes
In clinical gait analysis, it is challenging to acquire usable force plate data for a patient in a limited amount of time. The aim of this study was to compare three measurement protocols, to investigate if any one of them was more time-efficient than the others at collecting kinetic data. Three conditions were compared for 15 orthopaedic patients: 1) approaching the force plate with four steps, 2) approaching the force plate with six steps, and 3) approaching the force plate with four steps while stepping on a target one step before the first force plate...
July 8, 2017: Gait & Posture
https://www.readbyqxmd.com/read/28702747/management-of-supine-hypertension-complicating-neurogenic-orthostatic-hypotension
#12
Jacquie Baker, Kurt Kimpinski
Neurogenic orthostatic hypotension (NOH) can be present in a number of disorders, including synucleinopathies, autoimmune disorders, and various genetic disorders. All are characterized by defective norepinephrine release from sympathetic terminals upon standing, resulting in impaired vasoconstriction. NOH is defined as a drop in systolic blood pressure ≥20 mmHg or diastolic blood pressure ≥10 mmHg, or both, within 3 minutes of standing or head up-tilt at a minimum of 60°. However, approximately 50% of patients have associated supine hypertension, which greatly complicates treatment...
July 12, 2017: CNS Drugs
https://www.readbyqxmd.com/read/28700454/posterior-only-hemivertebra-resection-for-congenital-cervicothoracic-scoliosis-correcting-neck-tilt-and-balancing-the-shoulders
#13
Zhonghui Chen, Yong Qiu, Zezhang Zhu, Song Li, Xi Chen, Liang Xu, Xu Sun
STUDY DESIGN: A retrospective study. OBJECTIVE: To evaluate radiographic and cosmetic outcomes following posterior-only cervicothoracic hemivertebra resection and instrumentation. SUMMARY OF BACKGROUND DATA: Cervicothoracic hemivertebra is a rare congenital deformity. It locates between the mobile cervical spine and the fixed thoracic spine, leading to rapid curve progression, shoulder imbalance, fixed torticollis and facial asymmetry. METHODS: This study reviewed a consecutive series of 18 patients with cervicothoracic hemivertebra...
July 11, 2017: Spine
https://www.readbyqxmd.com/read/28698085/modified-park-bench-position-for-superior-vermian-arteriovenous-malformations-and-dural-fistulas
#14
Rouzbeh Motiei-Langroudi, Christoph J Griessenauer, Abdulrahman Y Alturki, Paul H Chapman, Christopher S Ogilvy, Ajith J Thomas
OBJECTIVES: Arteriovenous malformations (AVMs) of the superior cerebellar vermis and dural arteriovenous fistulas (dAVFs) draining into tentorial venous structures are uncommon lesions. Various surgical approaches and positions have been used to gain access. METHODS: We present our experience with 10 superior vermian AVMs and 3 dAVFs with retrograde transverse sinus or torcular drainage, each resected through a supracerebellar infratentorial approach in park bench position with modification of the neck and head position (vertex tilt-up instead of down)...
July 8, 2017: World Neurosurgery
https://www.readbyqxmd.com/read/28689660/structure-of-full-length-smc-and-rearrangements-required-for-chromosome-organization
#15
Marie-Laure Diebold-Durand, Hansol Lee, Laura B Ruiz Avila, Haemin Noh, Ho-Chul Shin, Haeri Im, Florian P Bock, Frank Bürmann, Alexandre Durand, Alrun Basfeld, Sihyun Ham, Jérôme Basquin, Byung-Ha Oh, Stephan Gruber
Multi-subunit SMC complexes control chromosome superstructure and promote chromosome disjunction, conceivably by actively translocating along DNA double helices. SMC subunits comprise an ABC ATPase "head" and a "hinge" dimerization domain connected by a 49 nm coiled-coil "arm." The heads undergo ATP-dependent engagement and disengagement to drive SMC action on the chromosome. Here, we elucidate the architecture of prokaryotic Smc dimers by high-throughput cysteine cross-linking and crystallography. Co-alignment of the Smc arms tightly closes the interarm space and misaligns the Smc head domains at the end of the rod by close apposition of their ABC signature motifs...
July 20, 2017: Molecular Cell
https://www.readbyqxmd.com/read/28684212/validation-of-a-new-2-d-technique-for-radiographic-wear-measurement-of-cemented-highly-cross-linked-polyethylene-acetabular-cups
#16
Brian Derbyshire, Bilal Barkatali
A new 2-D radiographic wear measurement system has been developed which enables the low wear of highly cross-linked polyethylene acetabular cups to be accurately and precisely measured from standard, pelvis radiographs. The software was validated using radiographic images of a measurement jig which could vary the cup orientation and simulate the effect of pelvic tilt/rotation. Wear was simulated using accurately measured plastic shims to vary the position of the femoral head relative to the cup. The effects of varying "wear" penetration, "wear" direction, cup orientation and X-ray focus position were assessed...
July 3, 2017: Medical Engineering & Physics
https://www.readbyqxmd.com/read/28682078/insight-into-water-structure-at-the-surfactant-surfaces-and-in-micro-emulsion-confinement
#17
Chayan Dutta, Anton Svirida, Muhammet Mammetkuliyev, Marina Rukhadze, Alexander V Benderskii
Interactions with surfactant molecules can significantly alter the structure of interfacial water. We present a comparative study of water/surfactant interactions using two different spectroscopic approaches: water at planar surfactant monolayers by sum frequency generation (SFG) spectroscopy, and interfacial water confined in reverse micelles formed by the same surfactants using infrared (IR) absorption spectroscopy. We report spectral features in the OH stretching region (3200-3700 cm(-1)) that are observed in both IR and SFG spectra, albeit with different relative amplitudes, for ionic surfactant sodium 1,4 bis 2 ethylhexylsulfosuccinate (AOT) and nonionic surfactant polyoxyethylene 4-lauryl ether (Brij L-4) reverse micelles in hexane and corresponding monolayers at the air/water interface...
July 6, 2017: Journal of Physical Chemistry. B
https://www.readbyqxmd.com/read/28681408/role-of-peripheral-vascular-resistance-as-an-indicator-of-cardiovascular-abnormalities-in-patients-with-parkinson-s-disease
#18
Monika Zawadka-Kunikowska, Joanna Słomko, Małgorzata Tafil-Klawe, Jacek J Klawe, Agnieszka Cudnoch-Jędrzejewska, Julia L Newton, Paweł Zalewski
The aim of this study was to evaluate cardiovascular autonomic modulation in response to an orthostatic stress in healthy subjects and Parkinson's disease (PD). The study included 47 controls and 56 PD patients divided into groups (vasoconstrictor PD, vasodilator PD, control) according to vasodilation/vasoconstriction response during 70° head up tilt test. Using Impedance cardiography (ICG) and electrocardiography (ECG) we measured stroke volume, cardiac output, left ventricular work index, left ventricular ejection time, acceleration index, index of contractility, Heather index, thoracic fluid content, total peripheral resistance, total arterial compliance...
July 5, 2017: Clinical and Experimental Pharmacology & Physiology
https://www.readbyqxmd.com/read/28681121/indexes-of-cerebral-autoregulation-do-not-reflect-impairment-in-syncope-insights-from-head-up-tilt-test-of-vasovagal-and-autonomic-failure-subjects
#19
Pedro Castro, João Freitas, Rosa Santos, Ronney Panerai, Elsa Azevedo
PURPOSE: The study of dynamic cerebral autoregulation (CA), which adapts cerebral blood flow to arterial blood pressure (ABP) fluctuations, has been limited in orthostatic intolerance syndromes, mainly due to its stationary prerequisites hardly to meet during maneuvers to provoke syncope itself. New techniques of continuous estimates of CA could overcome this pitfall. We aimed to evaluate CA during head-up tilt test in common conditions causing syncope. METHODS: We compared three groups: eight controls; eight patients with autonomic failure due to familial amyloidotic polyneuropathy; eight patients with vasovagal syncope (VVS)...
July 5, 2017: European Journal of Applied Physiology
https://www.readbyqxmd.com/read/28679450/constrained-posture-in-dentistry-a-kinematic-analysis-of-dentists
#20
Daniela Ohlendorf, Christina Erbe, Jennifer Nowak, Imke Hauck, Ingo Hermanns, Dirk Ditchen, Rolf Ellegast, David A Groneberg
BACKGROUND: How a dentist works, such as the patterns of movements performed daily, is also largely affected by the workstation Dental tasks are often executed in awkward body positions, thereby causing a very high degree of strain on the corresponding muscles. The objective of this study is to detect those dental tasks, during which awkward postures occur most frequently. The isolated analysis of static postures will examine the duration for which these postures are maintained during the corresponding dental, respectively non-dental, activities...
July 5, 2017: BMC Musculoskeletal Disorders
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