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https://www.readbyqxmd.com/read/28642732/autonomic-function-impairment-and-brain-perfusion-deficit-in-parkinson-s-disease
#1
Wei-Che Lin, Pei-Chin Chen, Chih-Cheng Huang, Nai-Wen Tsai, Hsiu-Ling Chen, Hung-Chen Wang, Kun-Hsien Chou, Meng-Hsiang Chen, Yi-Wen Chen, Cheng-Hsien Lu
INTRODUCTION: Autonomic disorders have been recognized as important Parkinson's disease (PD) components. Some vulnerable structures are related to the central autonomic network and have also been linked to autonomic function alterations. The aims of the study are to evaluate the severity of the autonomic dysfunction and the cortical hypoperfusion using arterial spin labeling (ASL) MRI. And then, possible relationships of significant between-group differences in perfusion pattern to clinical variables and autonomic functions were examined to determine the pharmaceutical effects of dopaminergic treatment on cerebral blood flow (CBF) in patients with PD...
2017: Frontiers in Neurology
https://www.readbyqxmd.com/read/28641686/a-case-study-of-human-roll-tilt-perception-in-hypogravity
#2
Torin K Clark, Laurence R Young
BACKGROUND: Increased gravito-inertial acceleration, or hypergravity, such as produced in a centrifuge or in an aircraft coordinated turn, causes humans to systematically overestimate their roll tilt in the dark. This is known as the "G-excess" illusion. We have previously modified a mathematical observer model of dynamic orientation perception to replicate these illusory tilt perceptions. This modified model also made a novel, previously untested, prediction that humans would underestimate acute roll tilt in reduced gravitational environments (hypogravity)...
July 1, 2017: Aerospace Medicine and Human Performance
https://www.readbyqxmd.com/read/28641680/ophthalmological-evaluation-of-integrated-resistance-and-aerobic-training-during-70-day-bed-rest
#3
Giovanni Taibbi, Ronita L Cromwell, Susana B Zanello, Patrice O Yarbough, Robert J Ploutz-Snyder, Bernard F Godley, Gianmarco Vizzeri
INTRODUCTION: We evaluated ophthalmic changes in healthy individuals who underwent integrated resistance and aerobic training (iRAT) during 70-d 6° head-down tilt (HDT) bed rest (BR). METHODS: Participants were selected using NASA standard screening procedures. Standardized NASA BR conditions were implemented. Subjects were randomly assigned to the iRAT protocol or no exercise during HDTBR. Weekly ophthalmic examinations were performed in the sitting (pre/post-BR only) and HDT (BR only) positions...
July 1, 2017: Aerospace Medicine and Human Performance
https://www.readbyqxmd.com/read/28628154/-morphological-changes-on-cochlear-hair-cells-of-rats-in-simulated-weightlessness-and-inboard-noise
#4
(no author information available yet)
OBJECTIVE: To observe the morphological changes on cochlear hair cells of rats in simulated weightlessness and inboard noise and to investigate the different changes in three turns of hair cells. METHODS: Thirty-two healthy SD rats, all males, were randomly divided into four groups: control group, weightlessness group, noise group and weightlessness+noise groups (n=8). Then rats were exposed to -30° head down tilt as simulated weightlessness and inboard noise including steady-state noise which was (72±2) dB SPL and impulse noise up to 160 dB SPL in spaceship environment...
June 18, 2017: Beijing da Xue Xue Bao. Yi Xue Ban, Journal of Peking University. Health Sciences
https://www.readbyqxmd.com/read/28626427/distinctive-steady-state-heart-rate-and-blood-pressure-responses-to-passive-robotic-leg-exercise-during-head-up-tilt-a-pilot-study-in-neurological-patients
#5
Amirehsan Sarabadani Tafreshi, Robert Riener, Verena Klamroth-Marganska
Introduction: Robot-assisted tilt table therapy was proposed for early rehabilitation and mobilization of patients after diseases such as stroke. A robot-assisted tilt table with integrated passive robotic leg exercise (PE) mechanism has the potential to prevent orthostatic hypotension usually provoked by verticalization. In a previous study with rather young healthy subjects [average age: 25.1 ± 2.6 years (standard deviation)], we found that PE effect on the cardiovascular system depends on the verticalization angle of the robot-assisted tilt table...
2017: Frontiers in Physiology
https://www.readbyqxmd.com/read/28624723/repeated-end-range-spinal-movement-while-seated-abolishes-the-proprioceptive-deficit-induced-by-prolonged-flexed-sitting-posture-a-study-assessing-the-statistical-and-clinical-significance-of-spinal-position-sense
#6
Vasileios Korakakis, Giannis Giakas, Vasilis Sideris, Rodney Whiteley
BACKGROUND: Sustained spinal flexion has been proposed to affect the properties of spinal tissues, increase postural muscle's activation latency and act detrimentally on proprioception. OBJECTIVES: This study evaluated the effect of flexed posture (FP) on spinal proprioception and assessed the immediate effect of spinal movement on the presumable flexion-induced proprioceptive deficit. DESIGN: Clinical measurement study. METHODS: Marker-based kinematic analyses of the head, spine, and pelvis were conducted on 50 individuals...
June 10, 2017: Musculoskeletal Science & Practice
https://www.readbyqxmd.com/read/28622188/differences-in-fundamental-sagittal-pelvic-parameters-based-on-age-sex-and-race
#7
Robert K Merrill, Jun S Kim, Dante M Leven, Joung Heon Kim, Joshua J Meaike, Rachel S Bronheim, Kelly I Suchman, Doug Nowacki, Sunder S Gidumal, Samuel K Cho
STUDY DESIGN: This is a retrospective cohort study. OBJECTIVE: To determine whether age, sex, and race have independent effects on sagittal pelvic parameters. SUMMARY OF BACKGROUND DATA: Pelvic parameters and sagittal balance correlate with health-related quality of life and are important for patient assessment and surgical planning. Age, sex, and race are 3 unalterable patient factors that may influence pelvic morphology. METHODS: We conducted a retrospective review of consecutive adult patients who presented to our radiology practice between 2010 and 2015 and had a standing, lateral lumbosacral radiograph...
June 15, 2017: Clinical Spine Surgery
https://www.readbyqxmd.com/read/28611153/effects-of-short-term-mild-hypercapnia-during-head-down-tilt-on-intracranial-pressure-and-ocular-structures-in-healthy-human-subjects
#8
Steven S Laurie, Gianmarco Vizzeri, Giovanni Taibbi, Connor R Ferguson, Xiao Hu, Stuart M C Lee, Robert Ploutz-Snyder, Scott M Smith, Sara R Zwart, Michael B Stenger
Many astronauts experience ocular structural and functional changes during long-duration spaceflight, including choroidal folds, optic disc edema, globe flattening, optic nerve sheath diameter (ONSD) distension, retinal nerve fiber layer thickening, and decreased visual acuity. The leading hypothesis suggests that weightlessness-induced cephalad fluid shifts increase intracranial pressure (ICP), which contributes to the ocular structural changes, but elevated ambient CO2 levels on the International Space Station may also be a factor...
June 2017: Physiological Reports
https://www.readbyqxmd.com/read/28607756/heart-rate-variability-is-differentially-altered-in-multiple-sclerosis-implications-for-acute-worsening-and-progressive-disability
#9
Valeria Studer, Camilla Rocchi, Caterina Motta, Benedetta Lauretti, Jacopo Perugini, Laura Brambilla, Lorena Pareja-Gutierrez, Giorgia Camera, Francesca Romana Barbieri, Girolama A Marfia, Diego Centonze, Silvia Rossi
BACKGROUND: Sympathovagal imbalance has been associated with poor prognosis in chronic diseases, but there is conflicting evidence in multiple sclerosis. OBJECTIVES: The objective of this study was to investigate the autonomic nervous system dysfunction correlation with inflammation and progression in multiple sclerosis. METHODS: Heart rate variability was analysed in 120 multiple sclerosis patients and 60 healthy controls during supine rest and head-up tilt test; the normalised units of low frequency and high frequency power were considered to assess sympathetic and vagal components, respectively...
April 2017: Multiple Sclerosis Journal—Experimental, Translational and Clinical
https://www.readbyqxmd.com/read/28604989/cannulation-of-the-internal-jugular-vein-without-head-down-tilt-positions-when-it-is-safe
#10
Anton A Kasatkin, Anna R Nigmatullina, Aleksandr L Urakov
No abstract text is available yet for this article.
June 6, 2017: Journal of Vascular Access
https://www.readbyqxmd.com/read/28604410/feasibility-and-neurobehavioral-changes-of-10-day-simulated-microgravity-in-acute-ischemic-stroke-patients
#11
Kyo-In Koo, Dae Kwon Park, Chang Ho Hwang
OBJECTIVE: The aim of the study was to investigate feasibility and functional changes of simulated microgravity with 6-degree head-down-tilt (HDT) bed rest in acute ischemic stroke. DESIGN: Patients without lesions in the cingulate cortex and/or cerebellum were enrolled. They underwent HDT for 30 minutes twice per day for 10 weekdays. Systolic blood pressure, diastolic blood pressure, and heart rate were measured before the HDT, immediately after, and also 30 minutes after the stop...
June 9, 2017: American Journal of Physical Medicine & Rehabilitation
https://www.readbyqxmd.com/read/28604343/breathing-100-oxygen-during-water-immersion-improves-postimmersion-cardiovascular-responses-to-orthostatic-stress
#12
John P Florian, Ki H Chon, Luca Faes, Barbara E Shykoff
Physiological compensation to postural stress is weakened after long-duration water immersion (WI), thus predisposing individuals to orthostatic intolerance. This study was conducted to compare hemodynamic responses to postural stress following exposure to WI alone (Air WI), hyperbaric oxygen alone in a hyperbaric chamber (O2 HC), and WI combined with hyperbaric oxygen (O2 WI), all at a depth of 1.35 ATA, and to determine whether hyperbaric oxygen is protective of orthostatic tolerance. Thirty-two healthy men underwent up to 15 min of 70° head-up tilt (HUT) testing before and after a single 6-h resting exposure to Air WI (N = 10), O2 HC (N = 12), or O2 WI (N = 10)...
December 2016: Physiological Reports
https://www.readbyqxmd.com/read/28601994/radiologic-features-of-dropped-head-syndrome-in-the-overall-sagittal-alignment-of-the-spine
#13
Kazuki Hashimoto, Hiroshi Miyamoto, Terumasa Ikeda, Masao Akagi
PURPOSE: Dropped head syndrome (DHS) is a rare clinical entity which is defined as a chin-on-chest deformity in the standing or sitting position, resulting from sagittal imbalance of the cervical region. The purpose of the present study was to clarify the radiologic features of DHS in the overall sagittal alignment of the spine. We also investigated the changes in sagittal alignment after correction surgery for DHS. METHODS: Twenty DHS patients [1 male and 19 female, with an average age of 78...
June 10, 2017: European Spine Journal
https://www.readbyqxmd.com/read/28600534/intracranial-fluid-redistribution-but-no-white-matter-microstructural-changes-during-a-spaceflight-analog
#14
Vincent Koppelmans, Ofer Pasternak, Jacob J Bloomberg, Yiri E De Dios, Scott J Wood, Roy Riascos, Patricia A Reuter-Lorenz, Igor S Kofman, Ajitkumar P Mulavara, Rachael D Seidler
The neural correlates of spaceflight-induced sensorimotor impairments are unknown. Head down-tilt bed rest (HDBR) serves as a microgravity analog because it mimics the headward fluid shift and axial body unloading of spaceflight. We investigated focal brain white matter (WM) changes and fluid shifts during 70 days of 6° HDBR in 16 subjects who were assessed pre (2x), during (3x), and post-HDBR (2x). Changes over time were compared to those in control subjects (n = 12) assessed four times over 90 days. Diffusion MRI was used to assess WM microstructure and fluid shifts...
June 9, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28598949/subjective-visual-vertical-in-idiopathic-bilateral-vestibular-hypofunction-enhanced-role-of-vision-neck-and-body-proprioception
#15
Michel Toupet, Christian Van Nechel, Charlotte Hautefort, Ulla Duquesne, Sylvie Heuschen, Alexis Bozorg Grayeli
INTRODUCTION: We aimed to study the participation of proprioceptive and visual inputs in subjective visual vertical (SVV) in bilateral vestibular hypofunction and in normal subjects. STUDY DESIGN: Prospective case-control study. SETTING: Tertiary referral center. MATERIALS AND METHODS: SVV (six replicates) was measured on a tiltable rehabilitation seat in 26 adult patients with idiopathic bilateral vestibular hypofunction (IBVH) and 33 adult controls...
June 8, 2017: Otology & Neurotology
https://www.readbyqxmd.com/read/28585146/deceleration-capacity-a-novel-measure-for-autonomic-nervous-system-in-patients-with-vasovagal-syncope-on-tilt-table-testing
#16
Fen Huang, Chun-Fang Xu, Xiao-Yan Deng, Ping Zuo, Fan Lin, Jing-Jing Fan, Wen-Jia Xu, Xiao-Yun Yang
This study was to investigate the changes of autonomic nerve function and hemodynamics in patients with vasovagal syncope (VVS) during head-up tilt-table testing (HUT). HUT was performed in 68 patients with unexplained syncope and 18 healthy subjects served as control group. According to whether bradycardia, hypotension or both took place during the onset of syncope, the patients were divided during the test into three subgroups: vasodepressor syncope (VD), cardioinhibitory syncope (CI) and mixed syncope (MX) subgroups...
June 2017: Journal of Huazhong University of Science and Technology. Medical Sciences
https://www.readbyqxmd.com/read/28579743/novel-positioning-sensor-with-real-time-feedback-for-improved-postoperative-positioning-pilot-study-in-control-subjects
#17
Frank L Brodie, David A Ramirez, Sundar Pandian, Kelly Woo, Ashwin Balakrishna, Eugene De Juan, Hyuck Choo, Robert H Grubbs
INTRODUCTION: Repair of retinal detachment frequently requires use of intraocular gas. Patients are instructed to position themselves postoperatively to appose the intraocular bubble to the retinal break(s). We developed a novel wearable wireless positioning sensor, which provides real-time audiovisual feedback on the accuracy of positioning. METHODS: Eight healthy volunteers wore the wireless sensor for 3 hours while instructed to maintain their head tilted toward the 2 o'clock meridian with no audiovisual feedback...
2017: Clinical Ophthalmology
https://www.readbyqxmd.com/read/28577333/mri-based-assessment-of-acute-effect-of-head-down-tilt-position-on-intracranial-hemodynamics-and-hydrodynamics
#18
Shota Ishida, Tosiaki Miyati, Naoki Ohno, Shinnosuke Hiratsuka, Noam Alperin, Mitsuhito Mase, Toshifumi Gabata
PURPOSE: To quantify the acute effect of the head-down tilt (HDT) posture on intracranial hemodynamics and hydrodynamics. MATERIALS AND METHODS: We evaluated the intracranial physiological parameters, blood flow-related parameters, and brain morphology in the HDT (-6° and -12°) and the horizontal supine (HS) positions. Seven and 15 healthy subjects were scanned for each position using 3.0 T magnetic resonance imaging system. The peak-to-peak intracranial volume change, the peak-to-peak cerebrospinal fluid (CSF) pressure gradient (PGp-p ), and the intracranial compliance index were calculated from the blood and CSF flow determined using a cine phase-contrast technique...
June 3, 2017: Journal of Magnetic Resonance Imaging: JMRI
https://www.readbyqxmd.com/read/28570360/atlanto-axial-subluxation-after-adenoidectomy
#19
Isabel Theresia Gross, Laleh Bahar-Posey
Atlanto-axial subluxation is a rare but potentially serious complication after otolaryngological procedures. We are describing a case of a 4-year-old child who developed atlanto-axial subluxation of the cervical spine after adenoidectomy. Our patient underwent adenoidectomy and, 18 days later, presented to the emergency department with her neck tilted to the left in a cock-robin position and complaining of neck pain persisting since the surgery. A multiplanar 3-dimensional computed tomography was obtained and confirmed the diagnosis of an atlanto-axial subluxation (Fielding type 3)...
June 2017: Pediatric Emergency Care
https://www.readbyqxmd.com/read/28567271/the-accuracy-and-precision-of-position-and-orientation-tracking-in-the-htc-vive-virtual-reality-system-for-scientific-research
#20
Diederick C Niehorster, Li Li, Markus Lappe
The advent of inexpensive consumer virtual reality equipment enables many more researchers to study perception with naturally moving observers. One such system, the HTC Vive, offers a large field-of-view, high-resolution head mounted display together with a room-scale tracking system for less than a thousand U.S. dollars. If the position and orientation tracking of this system is of sufficient accuracy and precision, it could be suitable for much research that is currently done with far more expensive systems...
May 2017: I-Perception
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