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https://www.readbyqxmd.com/read/29142084/impaired-vestibular-responses-in-internuclear-ophthalmoplegia-association-and-dissociation
#1
Seo-Young Choi, Hyo-Jung Kim, Ji-Soo Kim
OBJECTIVE: To determine the role of the medial longitudinal fasciculus (MLF) in conveying vestibular signals. METHODS: In 10 patients with isolated acute unilateral internuclear ophthalmoplegia (INO) due to an acute stroke, we performed comprehensive vestibular evaluation using video-oculography, head impulse tests with a magnetic search coil technique, bithermal caloric tests, tests for the ocular tilt reaction, and measurements of subjective visual vertical and cervical and ocular vestibular evoked myogenic potentials (VEMPs)...
November 15, 2017: Neurology
https://www.readbyqxmd.com/read/29140458/direct-measurements-of-skin-eye-lens-and-thyroid-dose-during-pediatric-brain-ct-examinations
#2
Agapi Ploussi, Ioannis Stathopoulos, Vasileios Syrgiamiotis, Triantafillia Makri, Christiana Hatzigiorgi, Kalliopi Platoni, Eleftheria Carinou, Efstathios P Efstathopoulos
Pediatric brain computed tomography (CT) is identified as the most frequent CT examination in children. The aim of the study is the direct measurement of skin, eye lens and thyroid dose in pediatric patients during brain CT examinations. The study included 35 pediatric patients who underwent brain CT examinations. The patients were categorized in three age groups: Group A (age range: 0.8-1 years), Group B (age range: 2.0-4.9 years) and Group C (age range: 5.5-15.5 years). thermoluminescent dosimeters (TLDs) were placed on the eyes, the frontal region of the head, the mastoid apophysis and the thyroid gland...
November 13, 2017: Radiation Protection Dosimetry
https://www.readbyqxmd.com/read/29136243/structure-and-electrical-properties-of-dna-nanotubes-embedded-in-lipid-bilayer-membranes
#3
Himanshu Joshi, Prabal K Maiti
Engineering the synthetic nanopores through lipid bilayer membrane to access the interior of a cell is a long persisting challenge in biotechnology. Here, we demonstrate the stability and dynamics of a tile-based 6-helix DNA nanotube (DNT) embedded in POPC lipid bilayer using the analysis of 0.2 μs long equilibrium MD simulation trajectories. We observe that the head groups of the lipid molecules close to the lumen cooperatively tilt towards the hydrophilic sugar-phosphate backbone of DNA and form a toroidal structure around the patch of DNT protruding in the membrane...
November 10, 2017: Nucleic Acids Research
https://www.readbyqxmd.com/read/29131019/utility-of-autonomic-function-tests-to-differentiate-dementia-with-lewy-bodies-and-parkinson-disease-with-dementia-from-alzheimer-disease
#4
Shuta Toru, Tadashi Kanouchi, Takanori Yokota, Yosuke Yagi, Akira Machida, Takayoshi Kobayashi
OBJECTIVE: We studied autonomic disturbance in patients with dementia with Lewy bodies (DLB), Parkinson disease with dementia (PDD), Alzheimer disease (AD), to determine whether autonomic function tests can be used to distinguish these disorders. METHODS: Autonomic function was tested in 56 patients with DLB, 37 patients with PDD, and 59 patients with AD by using the sympathetic skin response, coefficient of variation in R-R interval, the head-up tilt test, serum norepinephrine concentration, and 123I-meta-iodobenzylguanidine cardiac scintigraphy...
November 13, 2017: European Neurology
https://www.readbyqxmd.com/read/29129037/eye-movement-abnormalities-in-middle-cerebellar-peduncle-strokes
#5
Sung-Hee Kim, Ji-Soo Kim
The middle cerebellar peduncle (MCP) is a major conduit for cortico-ponto-cerebellar fibers that convey information related to eye movements. This study aims to elucidate eye movement abnormalities that arise from lesions confined to the MCP. In 23 patients with acute strokes restricted to unilateral MCPs, we investigated the clinical features and ocular motor findings including spontaneous nystagmus, saccades, smooth pursuit, ocular tilt reaction, and head impulse tests. Bithermal caloric tests and audiometry were also performed...
November 11, 2017: Acta Neurologica Belgica
https://www.readbyqxmd.com/read/29128915/mri-kinematic-analysis-of-t1-sagittal-motion-between-cervical-flexion-and-extension-positions-in-145-patients
#6
Koji Tamai, Zorica Buser, Permsak Paholpak, Kittipong Sessumpun, Patrick C Hsieh, Hiroaki Nakamura, Jeffrey C Wang
PURPOSE: Although the T1 vertebra is considered as an important factor of cervical balance, little is known about its motion between flexion and extension. The purpose of present study was to analyze the T1 sagittal motion using kinematic magnetic resonance imaging (kMRI), and to identify factors that relate to T1 sagittal motion. METHODS: We retrospectively analyzed 145 kMR images taken in weight-bearing neutral, flexion and extension positions. Cervical balance parameters were evaluated in each position...
November 11, 2017: European Spine Journal
https://www.readbyqxmd.com/read/29123883/delayed-autonomic-neuropathy-in-a-patient-with-diethylene-glycol-poisoning-a-case-report
#7
Hiroki Kamada, Hideaki Suzuki, Saori Yamamoto, Ryosuke Nomura, Shigeki Kushimoto
Case: A 72-year-old man presented to our hospital after ingesting insecticide containing approximately 2 mL/kg diethylene glycol, which exceeded the lethal dose of 1 mL/kg. The patient recovered from critical symptoms on acute phase until day 3, but received artificial ventilation for muscle weakness secondary to sensorimotor neuropathy on days 11-54. Outcome: Even after marked improvement from sensorimotor neuropathy, the patient continued to complain of orthostatic hypotension...
July 2017: Acute Medicine & Surgery
https://www.readbyqxmd.com/read/29118083/the-effect-of-magnification-loupes-on-dental-hygienists-posture-while-exploring
#8
Emily A Ludwig, Gayle B McCombs, Susan L Tolle, Daniel M Russell
Purpose: The purpose of this study was to determine the effects of dental magnification loupes on posture during instrumentation.Methods: A convenience sample of 27 right-handed dental hygienists, with no prior history of injuries or disabilities of the head, neck, or trunk region, enrolled in the study. Baseline posture calibration was taken and tri-axial accelerometers were placed on four locations of the head and trunk (occipital region of head; cervical vertebrae C5; thoracic vertebrae T5; lumbar vertebrae L1) to measure acceleration and the orientation of the body to gravity...
August 2017: Journal of Dental Hygiene: JDH
https://www.readbyqxmd.com/read/29117834/open-wedge-osteotomy-with-ulnar-shortening-for-madelung-deformity-using-a-computer-generated-template
#9
Sho Yanagisawa, Takehiko Takagi, Tsuyoshi Murase, Yuka Kobayashi, Masahiko Watanabe
A variety of osteotomies have been reported to correct Madelung deformity using plain radiographs. However, evaluation of the deformity using 2-dimensional plain radiography is difficult because of its complex 3-dimensional nature. Therefore, we performed corrective osteotomy using recently developed 3D simulation technology on an adult woman with Madelung deformity, and achieved an excellent outcome. In this study, we calculated the amount of parallel displacement as well as the rotational angle for more precise correction, and performed open wedge osteotomy...
December 2017: Journal of Hand Surgery Asian-Pacific Volume
https://www.readbyqxmd.com/read/29116398/predictive-factors-for-corrective-effect-of-inferior-rectus-recession-for-congenital-superior-oblique-palsy
#10
Manabu Miyata, Kiyo Shibata, Ichiro Hamasaki, Masayuki Hata, Yuki Muraoka, Munemitsu Yoshikawa, Satoshi Hasebe, Hiroshi Ohtsuki
PURPOSE: To identify preoperative factors associated with the surgical corrective effect of contralateral inferior rectus recession (IRR) for vertical deviation in patients with congenital superior oblique palsy (SOP). METHODS: This retrospective study included 20 treatment-naïve patients with unilateral congenital SOP (age range, 6-79 years) who underwent contralateral IRR according to our basic policy to select IRR for paretic eye fixation. The corrective effect (°/mm) of IRR was defined as the difference in the vertical deviation at the primary gaze position between before and 6-18 months after surgery per distance of recession...
November 7, 2017: Graefe's Archive for Clinical and Experimental Ophthalmology
https://www.readbyqxmd.com/read/29111992/cardiovascular-and-cerebral-hemodynamics-in-asymptomatic-healthy-subjects-with-without-abnormal-head-up-tilt-test-versus-recurrent-fainters
#11
Antonio González-Hermosillo, Manuel Sierra-Beltrán, Ulises López-Peña, Andrei Kostin, Guadalupe Hernández-Pacheco, Claudia Lerma
PURPOSE: The aim of this study was to compare hemodynamic and autonomic responses during head-up tilt test (HUTT) between healthy volunteers and patients with a history of fainting and confirmed vasovagal syncope. We hypothesize that the autonomic and hemodynamic physiologic responses remain intact during orthostatic stress in people without previous fainting and negative HUTT, but deteriorate similarly in patients with recurrent vasovagal syncope and in asymptomatic healthy subjects who develop a vasovagal response during HUTT...
October 27, 2017: Journal of Clinical Neurophysiology: Official Publication of the American Electroencephalographic Society
https://www.readbyqxmd.com/read/29110073/vasovagal-syncope-is-associated-with-poor-prognosis-in-patients-with-left-ventricular-dysfunction
#12
Yoshiaki Yamaguchi, Koichi Mizumaki, Kunihiro Nishida, Tamotsu Sakamoto, Yosuke Nakatani, Naoya Kataoka, Koichiro Kinugawa, Hiroshi Inoue
Vasovagal syncope (VVS) is known to have a benign prognosis and be associated with enhanced contraction and activation of the left ventricular (LV) mechanoreceptors. However, a little is known about VVS in patients with LV dysfunction. The present study aimed to investigate the prevalence and prognosis of VVS in patients with LV dysfunction. We enrolled 368 patients with unexplained syncope. In 7 of these patients, LV ejection fraction was lower than 40%. The results of a head-up tilt test (HUT) and the recurrence of syncope were compared between these 7 patients with LV dysfunction and the remaining patients...
November 6, 2017: Heart and Vessels
https://www.readbyqxmd.com/read/29107952/hereditary-angioedema-assessing-the-hypothesis-for-underlying-autonomic-dysfunction
#13
Maddalena A Wu, Francesco Casella, Francesca Perego, Chiara Suffritti, Nada Afifi Afifi, Eleonora Tobaldini, Andrea Zanichelli, Chiara Cogliati, Nicola Montano, Marco Cicardi
BACKGROUND: Attacks of Hereditary Angioedema due to C1-inhibitor deficiency (C1-INH-HAE)are often triggered by stressful events/hormonal changes. OBJECTIVE: Our study evaluates the relationship between autonomic nervous system (ANS) and contact/complement system activation. METHODS: Twenty-three HAE patients (6 males, mean age 47.5±11.4 years) during remission and 24 healthy controls (8 males, mean age 45.3±10.6 years) were studied. ECG, beat-by-beat blood pressure, respiratory activity were continuously recorded during rest (10') and 75-degrees-head-up tilt (10')...
2017: PloS One
https://www.readbyqxmd.com/read/29101737/is-perception-of-visual-verticality-intact-in-patients-with-idiopathic-cervical-dystonia
#14
Joke De Pauw, Willem De Hertogh, Rudy Mercelis, Wim Saeys, Ann Hallemans, Sarah Michiels, Steven Truijen, Patrick Cras
Idiopathic cervical dystonia (CD) is a focal dystonia characterized by an abnormal tilted or twisted head position. This abnormal head position could lead to a distorted perception of the visual vertical and spatial orientation. The aim of this cross-sectional study was to investigate whether the perception of the visual vertical is impaired in patients with CD. The subjective visual vertical test (SVV) was measured in 24 patients with CD and 30 controls. The SVV test is conducted in a completely darkened room...
November 3, 2017: Acta Neurologica Belgica
https://www.readbyqxmd.com/read/29097958/unresolved-congenital-torticollis-and-its-consequences-a-report-of-2-cases
#15
Mette Hobaek Siegenthaler
Objective: The purpose of this report was to describe the clinical presentation and case management of 2 children with congenital torticollis. Clinical Features: Two male children (ages 6 and 10 years) presented to a chiropractic clinic with a history of congenital torticollis. They showed signs and symptoms of postural deficiency and developmental delay: posterior plagiocephaly, facial scoliosis, head tilt, compensatory thoracic scoliosis, decreased range of motion in the cervical spine, palpable decreased segmental motion of the upper cervical spine, and an age-related delay in throwing and catching a ball and in one-leg standing...
September 2017: Journal of Chiropractic Medicine
https://www.readbyqxmd.com/read/29097591/head-orientation-of-walking-blowflies-is-controlled-by-visual-and-mechanical-cues
#16
José Monteagudo, Jens P Lindemann, Martin Egelhaaf
During locomotion animals employ visual and mechanical cues in order to establish the orientation of their head, which reflects the orientation of the visual coordinate system. However, in certain situations, contradictory cues may suggest different orientations relative to the environment. We recorded blowflies walking on a horizontal or tilted surface surrounded by visual cues suggesting a variety of orientations. We found that the different orientations relative to gravity of visual cues and walking surface were integrated, with the orientation of the surface being the major contributor to head orientation, while visual cues and gravity also play an important role...
November 2, 2017: Journal of Experimental Biology
https://www.readbyqxmd.com/read/29096996/normal-tension-glaucoma-has-normal-intracranial-pressure-a-prospective-study-of-intracranial-pressure-and-intraocular-pressure-in-different-body-positions
#17
Christina Lindén, Sara Qvarlander, Gauti Jóhannesson, Elias Johansson, Fanny Östlund, Jan Malm, Anders Eklund
PURPOSE: To test the hypothesis that normal-tension glaucoma (NTG) is caused by an increased pressure difference across the lamina cribrosa (LC) related to a low intracranial pressure (ICP). DESIGN: Prospective case-control study. PARTICIPANTS: Thirteen NTG patients (9 women; median 71 [range: 56-83] years) were recruited for investigation with the same protocol as 11 healthy volunteers (8 women; 47 [30-59] years). A larger control group (n = 51; 30 women; 68 [30-81] years) was used only for ICP comparison in supine position...
October 30, 2017: Ophthalmology
https://www.readbyqxmd.com/read/29077223/sensitivity-of-serum-concentration-of-cartilage-biomarkers-to-21-days-of-bed-rest
#18
Anna-Maria Liphardt, Annegret Mündermann Farnsworth, Thomas P Andriacchi, Silvia Achtzehn, Martina Heer, Joachim Mester
The objective of the study was to test the hypothesis that serum levels of cartilage oligomeric matrix protein (COMP) would decrease and serum levels of tumor-necrosis factor alpha (TNF-α) and selected matrix metalloproteinases (MMPs) would increase in response to bed rest (BR) and that these changes are unaffected by the intake of potassium bicarbonate or whey protein. Seven and 9 healthy male subjects participated in two 21-day 6° head down tilt crossover BR-studies with nutrition interventions. Serum samples were taken before, during, and after BR and biomarker concentrations were measured using commercial enzyme-linked immunosorbent assays...
October 27, 2017: Journal of Orthopaedic Research: Official Publication of the Orthopaedic Research Society
https://www.readbyqxmd.com/read/29072993/tilted-ecg-an-unusual-tilt-test-response
#19
Anunay Gupta, Neeraj Parakh, Rajnish Juneja
Tilt testing is a commonly used diagnostic tool to evaluate syncope of undetermined etiology. We hereby describe a twelve year old male child who developed presyncope during provocative head up tilt testing along with ST segment elevation in cardiac monitor during presyncope. Patient underwent repeat head up tilt testing along with holter monitoring which showed a left bundle branch block escape rhythm. Hence development of ST elevation was due to the improper filter application in single lead ECG monitor. This case highlights the importance of filters in electrocardiographic monitoring...
March 2017: Indian Pacing and Electrophysiology Journal
https://www.readbyqxmd.com/read/29070830/environmental-stress-and-vestibular-inputs-modulate-cardiovascular-responses-to-orthostasis-in-hypertensive-rats
#20
Gábor Raffai, Csongor Csekő, György Nádasy, László Kocsis, László Dézsi, Stephen N Hunyor, Emil Monos
The frequent accompaniment of hypertension by orthostatic circulatory disorders prompted us to investigate the effect of repeated and sustained head-up and head-down tilt positions on cardiovascular responses in spontaneously hypertensive rats vs. Wistar rats using radiotelemetric implants. Repeated orthostasis caused a transient elevation in blood pressure (7.3±1.7 mmHg) and heart rate (39.7±10.5 BPM), while repeated antiorthostasis led only to reversible tachycardia (85.6±11.7-54.3±16.8 BPM) in spontaneously hypertensive rats...
October 26, 2017: Hypertension Research: Official Journal of the Japanese Society of Hypertension
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