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https://www.readbyqxmd.com/read/29148786/n-alkanethiols-directly-grown-on-a-bare-si-111-surface-from-disordered-to-ordered-transition
#1
Lo-Yueh Chang, Yen-Chien Kuo, Hung Wei Shiu, Chia-Hsin Wang, Yao-Chang Lee, Yaw-Wen Yang, Shangjr Gwo, Chia-Hao Chen
We observed the growth phase transition of n-alkanethiols (AT), CH3(CH2)n-1SH, n = 4 ~16, directly implanted on a bare Si(111) surface, forming an AT monolayer. These monolayers were characterized with static water-contact angle, high-resolution X-ray photoelectron spectroscopy, near-edge X-ray fine-structure spectroscopy and grazing-angle reflection absorption Fourier-transform infrared spectroscopy. The integrated spectral results indicated that the implanted n-AT molecules formed a self-oriented and densely packed monolayer through formation of an S-Si bond...
November 17, 2017: Langmuir: the ACS Journal of Surfaces and Colloids
https://www.readbyqxmd.com/read/29146395/correlation-between-intraoperative-proximal-segment-rotation-and-post-sagittal-split-ramus-osteotomy-relapse-a-three-dimensional-cone-beam-computed-tomography-study
#2
B-J Choi, B-S Lee, Y-D Kwon, J-W Lee, S-U Yun, K-S Ryu, J-Y Ohe
This study evaluated the effects of proximal segment rotation and the extent of mandibular setback on post-sagittal split ramus osteotomy (SSRO) relapse using three-dimensional (3D) analysis. Thirty-one patients diagnosed with a skeletal class III malocclusion who underwent SSRO alone were enrolled in this study. The movements of the mandibular condyles were assessed using cone beam computed tomography (CBCT) and a 3D imaging program at ≤1 month before the operation (T0), 1 week after the operation (T1), and 6 months (T2) and 1year (T3) postoperative...
November 13, 2017: International Journal of Oral and Maxillofacial Surgery
https://www.readbyqxmd.com/read/29140920/oral-lithium-as-an-adjunctive-therapy-during-radioiodine-treatment-for-hyperthyroidism
#3
Emmanuel N B Hammond, Yaw A Amoako, Mboyo-Di-Tamba W H Vangu
No abstract text is available yet for this article.
December 2017: Nuclear Medicine Communications
https://www.readbyqxmd.com/read/29140407/targeted-treatment-of-yaws-with-household-contact-tracing-how-much-do-we-miss
#4
Louise Dyson, Michael Marks, Oliver M Crook, Oliver Sokana, Anthony W Solomon, Alex Bishop, David C W Mabey, T Déirdre Hollingsworth
Yaws is a disabling bacterial infection primarily found in warm and humid tropical areas. The World Health Organisation strategy mandates an initial round of total community treatment (TCT) with single-dose azithromycin followed either by further TCT or active case finding and treatment of cases and their contacts (the Morges strategy). We wish to investigate the effectiveness of the Morges strategy. We employ a stochastic household model to study the transmission of infection using data collected from a pre-TCT survey conducted in the Solomon Islands...
November 13, 2017: American Journal of Epidemiology
https://www.readbyqxmd.com/read/29137663/patent-landscape-of-neglected-tropical-diseases-an-analysis-of-worldwide-patent-families
#5
Folahanmi Tomiwa Akinsolu, Vitor Nobre de Paiva, Samuel Santos Souza, Orsolya Varga
BACKGROUND: "Neglected Tropical Diseases" (NTDs) affect millions of people in Africa, Asia and South America. The two primary ways of strategic interventions are "preventive chemotherapy and transmission control" (PCT), and "innovative and intensified disease management" (IDM). In the last 5 years, phenomenal progress has been achieved. However, it is crucial to intensify research effort into NTDs, because of the emerging drug resistance. According to the World Health Organization (WHO), the term NTDs covers 17 diseases, namely buruli ulcer, Chagas disease, dengue, dracunculiasis, echinococcosis, trematodiasis, human African trypanosomiasis, leishmaniasis, leprosy, lymphatic filariasis, onchocerciasis, rabies, schistosomiasis, soil-transmitted helminthes, taeniasis, trachoma, and yaws...
November 14, 2017: Globalization and Health
https://www.readbyqxmd.com/read/29135873/the-effect-of-peripheral-vestibular-recovery-on-improvements-in-vestibulo-ocular-reflexes-and-balance-control-after-acute-unilateral-peripheral-vestibular-loss
#6
John H J Allum, Alja Scheltinga, Flurin Honegger
BACKGROUND: Patients with an acute unilateral peripheral vestibular deficit (aUPVD), presumed to be caused by vestibular neuritis, show asymmetrical vestibular ocular reflexes (VORs) that improve over time. Questions arise regarding how much of the VOR improvement is due to peripheral recovery or central compensation, and whether differences in peripheral recovery influence balance control outcomes. METHODS: Thirty patients were examined at aUPVD onset and 3, 6, and 13 weeks later with four different VOR tests: caloric tests; rotating (ROT) chair tests performed in yaw with angular accelerations of 5 and 20 degrees/s; and video head impulse tests (vHIT) in the yaw plane...
December 2017: Otology & Neurotology
https://www.readbyqxmd.com/read/29132760/hepatitis-c-in-sub-saharan-africa-the-current-status-and-recommendations-for-achieving-elimination-by-2030
#7
REVIEW
Mark W Sonderup, Mary Afihene, Reidwaan Ally, Betty Apica, Yaw Awuku, Lina Cunha, Geoffrey Dusheiko, Neliswa Gogela, Marie-Jeanne Lohouès-Kouacou, Phillip Lam, Olufunmilayo Lesi, Papa Saliou Mbaye, Emmanuel Musabeyezu, Betty Musau, Olesegun Ojo, John Rwegasha, Barbara Scholz, Abate B Shewaye, Christian Tzeuton, Chris Kassianides, C Wendy Spearman
In 2016, WHO adopted a strategy for the elimination of viral hepatitis by 2030. Africa, and more specifically, sub-Saharan Africa, carries a substantial portion of the global burden of viral hepatitis, especially chronic hepatitis B and hepatitis C virus infections. The task that lies ahead for sub-Saharan Africa to achieve elimination is substantial, but not insurmountable. Major developments in the management of hepatitis C have put elimination within reach, but several difficulties will need to be navigated on the path to elimination...
December 2017: Lancet. Gastroenterology & Hepatology
https://www.readbyqxmd.com/read/29132759/hepatitis-b-in-sub-saharan-africa-strategies-to-achieve-the-2030-elimination-targets
#8
REVIEW
C Wendy Spearman, Mary Afihene, Reidwaan Ally, Betty Apica, Yaw Awuku, Lina Cunha, Geoffrey Dusheiko, Neliswa Gogela, Chris Kassianides, Michael Kew, Philip Lam, Olufunmilayo Lesi, Marie-Jeanne Lohouès-Kouacou, Papa Saliou Mbaye, Emmanuel Musabeyezu, Betty Musau, Olusegun Ojo, John Rwegasha, Barbara Scholz, Abate B Shewaye, Christian Tzeuton, Mark W Sonderup
The WHO global health sector strategy on viral hepatitis, created in May, 2016, aims to achieve a 90% reduction in new cases of chronic hepatitis B and C and a 65% reduction in mortality due to hepatitis B and C by 2030. Hepatitis B virus (HBV) is endemic in sub-Saharan Africa, and despite the introduction of universal hepatitis B vaccination and effective antiviral therapy, the estimated overall seroprevalence of hepatitis B surface antigen remains high at 6·1% (95% uncertainty interval 4·6-8·5). In this Series paper, we have reviewed the literature to examine the epidemiology, burden of liver disease, and elimination strategies of hepatitis B in sub-Saharan Africa...
December 2017: Lancet. Gastroenterology & Hepatology
https://www.readbyqxmd.com/read/29128848/antimalarial-activity-of-malaria-box-compounds-against-plasmodium-falciparum-clinical-isolates
#9
Jersley D Chirawurah, Felix Ansah, Prince B Nyarko, Samuel Duodu, Yaw Aniweh, Gordon A Awandare
Malaria remains a major cause of childhood deaths in resource-limited settings. In the absence of an effective vaccine, drugs and other interventions have played very significant roles in combating the scourge of malaria. The recent reports of resistance to artemisinin necessitate the need for new antimalarial drugs with novel mechanisms of action. Towards the development of new, affordable and easily accessible antimalarial drugs for endemic regions, the Medicines for Malaria Venture (MMV) assembled a total of 400 active antimalarial compounds called the Malaria Box...
October 16, 2017: International Journal for Parasitology, Drugs and Drug Resistance
https://www.readbyqxmd.com/read/29128511/inducing-circular-vection-with-tactile-stimulation-encircling-the-waist
#10
Angelica M Tinga, Chris Jansen, Maarten J van der Smagt, Tanja C W Nijboer, Jan B F van Erp
In general, moving sensory stimuli (visual and auditory) can induce illusory sensations of self-motion (i.e. vection) in the direction opposite of the sensory stimulation. The aim of the current study was to examine whether tactile stimulation encircling the waist could induce circular vection (around the body's yaw axis) and to examine whether this type of stimulation would influence participants' walking trajectory and balance. We assessed the strength and direction of perceived self-motion while vision was blocked and while either receiving tactile stimulation encircling the waist clockwise or counterclockwise or no tactile stimulation...
November 9, 2017: Acta Psychologica
https://www.readbyqxmd.com/read/29122006/single-nucleotide-polymorphisms-in-the-angiogenic-and-lymphangiogenic-pathways-are-associated-with-lymphedema-caused-by-wuchereria-bancrofti
#11
Linda Batsa Debrah, Anna Albers, Alexander Yaw Debrah, Felix F Brockschmidt, Tim Becker, Christine Herold, Andrea Hofmann, Jubin Osei-Mensah, Yusif Mubarik, Holger Fröhlich, Achim Hoerauf, Kenneth Pfarr
BACKGROUND: Lymphedema (LE) is a chronic clinical manifestation of filarial nematode infections characterized by lymphatic dysfunction and subsequent accumulation of protein-rich fluid in the interstitial space-lymphatic filariasis. A number of studies have identified single nucleotide polymorphisms (SNPs) associated with primary and secondary LE. To assess SNPs associated with LE caused by lymphatic filariasis, a cross-sectional study of unrelated Ghanaian volunteers was designed to genotype SNPs in 285 LE patients as cases and 682 infected patients without pathology as controls...
November 9, 2017: Human Genomics
https://www.readbyqxmd.com/read/29119023/improvement-in-quality-metrics-outcomes-and-patient-and-family-satisfaction-in-a-neurosciences-intensive-care-unit-after-creation-of-a-dedicated-neurocritical-care-team
#12
Yaw Sarpong, Premkumar Nattanmai, Ginger Schelp, Robert Bell, Keerthivaas Premkumar, Erin Stapleton, Ashley McCormick, Christopher R Newey
Introduction: Dedicated neurointensivists have been shown to improve outcome measurements in the neurosciences intensive care unit (NSICU). Quality outcome data in relation to patient and family satisfaction is lacking. This study evaluated the impact of newly appointed neurointensivists and creation of a neurocritical care team on quality outcome measures including patient satisfaction in a NSICU. Methods: This is a retrospective study of data over 36 months from a 14-bed NSICU evaluating quality outcome measures and anonymous patient satisfaction questionnaires before and after neurointensivists appointment...
2017: Critical Care Research and Practice
https://www.readbyqxmd.com/read/29109828/enhancement-of-dye-sensitized-solar-cells-efficiency-using-mixed-phase-tio2-nanoparticles-as-photoanode
#13
Yi-Hua Fan, Ching-Yuan Ho, Yaw-Jen Chang
Dye-sensitized solar cell (DSSC) is a potential candidate to replace conventional silicon-based solar cells because of high efficiency, cheap cost, and lower energy consumption in comparison with silicon chip manufacture. In this report, mixed-phase (anatase and rutile nanoparticles) TiO2 photoanode was synthesized to investigate material characteristics, carriers transport, and photovoltaic performance for future DSSC application. Field-emission scanning electron microscope (SEM), X-ray diffraction (XRD), photoluminescence (PL), and UV-visible spectroscopy were used to characterize mixed TiO2 particles...
2017: Scanning
https://www.readbyqxmd.com/read/29108236/the-autophagic-inhibition-oral-squamous-cell-carcinoma-cancer-growth-of-16-hydroxy-cleroda-3-14-dine-15-16-olide
#14
Ming-Fang Cheng, Shian-Ren Lin, Fong-Jen Tseng, Yi-Chao Huang, May-Jywan Tsai, Yaw-Syan Fu, Ching-Feng Weng
16-hydroxycleroda-3, 13-dine-15, 16-olide (HCD) isolated from Polyalthia longifolia possesses numerous biological activities. Previous studies have reported that HCD can block phosphorylation activity of cancer cells to inhibit tumor cell growth, but the anti-tumor activity in oral squamous cell carcinoma is unrevealed. This study investigates the inhibiting effect of HCD on human OSCC cell growth; thereby, developing a new oral cancer drug. In in vitro cultured human OSCC cells (OECM1 and SAS) were employed to test the inhibitory growth of HCD via cell cytotoxic effect using 3-(4, 5-dimethylthiazol-2-yl)-2, 5-diphenyltetrazolium bromide (MTT) assay, Western blotting, and further determining of the inhibitory efficacy of tumor growth by a xenograft tumor on BALB/c male nude mice (in vivo test)...
October 3, 2017: Oncotarget
https://www.readbyqxmd.com/read/29107622/single-dose-azithromycin-to-treat-latent-yaws
#15
Michael Marks, David Mabey
No abstract text is available yet for this article.
October 26, 2017: Lancet Global Health
https://www.readbyqxmd.com/read/29107621/effectiveness-of-single-dose-azithromycin-to-treat-latent-yaws-a-longitudinal-comparative-cohort-study
#16
Oriol Mitjà, Camila González-Beiras, Charmie Godornes, Reman Kolmau, Wendy Houinei, Haina Abel, August Kapa, Raymond Paru, Sibauk V Bieb, James Wangi, Sergi Sanz, Kingsley Asiedu, Sheila A Lukehart, Quique Bassat
BACKGROUND: Treatment of latent yaws is a crucial component of the WHO yaws eradication strategy to prevent relapse and the resulting transmission to uninfected children. We assessed the effectiveness of single-dose azithromycin to treat patients with latent yaws. METHODS: This population-based cohort study included children (age <20 years) living on Lihir Island, Papua New Guinea, with high-titre (rapid plasma reagin titre ≥1:8) latent or active yaws, between April, 2013, and May, 2015...
October 26, 2017: Lancet Global Health
https://www.readbyqxmd.com/read/29089819/2017-multimodality-appropriate-use-criteria-for-noninvasive-cardiac-imaging-expert-consensus-of-the-asian-society-of-cardiovascular-imaging
#17
REVIEW
Kyongmin Sarah Beck, Jeong A Kim, Yeon Hyeon Choe, Sim Kui Hian, John Hoe, Yoo Jin Hong, Sung Mok Kim, Tae Hoon Kim, Young Jin Kim, Yun Hyeon Kim, Sachio Kuribayashi, Jongmin Lee, Lilian Leong, Tae-Hwan Lim, Bin Lu, Jae Hyung Park, Hajime Sakuma, Dong Hyun Yang, Tan Swee Yaw, Yung-Liang Wan, Zhaoqi Zhang, Shihua Zhao, Hwan Seok Yong
In 2010, the Asian Society of Cardiovascular Imaging (ASCI) provided recommendations for cardiac CT and MRI, and this document reflects an update of the 2010 ASCI appropriate use criteria (AUC). In 2016, the ASCI formed a new working group for revision of AUC for noninvasive cardiac imaging. A major change that we made in this document is the rating of various noninvasive tests (exercise electrocardiogram, echocardiography, positron emission tomography, single-photon emission computed tomography, radionuclide imaging, cardiac magnetic resonance, and cardiac computed tomography/angiography), compared side by side for their applications in various clinical scenarios...
November 2017: Korean Journal of Radiology: Official Journal of the Korean Radiological Society
https://www.readbyqxmd.com/read/29082745/cross-sectional-stepwise-approach-to-surveillance-steps-population-survey-of-noncommunicable-diseases-ncds-and-risk-factors-in-brunei-darussalam-2016
#18
Sok King Ong, Daphne Teck Ching Lai, Justin Yun Yaw Wong, Khairil Azhar Si-Ramlee, Lubna Abdul Razak, Norhayati Kassim, Zakaria Kamis, David Koh
This article provides a cross-sectional weighted measurement of noncommunicable diseases (NCDs) and risk factors prevalence among Brunei adult population using WHO STEPS methodology. A 2-staged randomized sampling was conducted during August 2015 to April 2016. Three-step surveillance included (1) interview using standardized questionnaire, (2) blood pressure and anthropometric measurements, and (3) biochemistry tests. Data weighting was applied. A total of 3808 adults aged 18 to 69 years participated in step 1; 2082 completed steps 2 and 3 measurements...
October 1, 2017: Asia-Pacific Journal of Public Health
https://www.readbyqxmd.com/read/29073145/the-cost-and-cost-effectiveness-of-rapid-testing-strategies-for-yaws-diagnosis-and-surveillance
#19
Christopher Fitzpatrick, Kingsley Asiedu, Anita Sands, Tita Gonzalez Pena, Michael Marks, Oriol Mitja, Filip Meheus, Patrick Van der Stuyft
BACKGROUND: Yaws is a non-venereal treponemal infection caused by Treponema pallidum subspecies pertenue. The disease is targeted by WHO for eradication by 2020. Rapid diagnostic tests (RDTs) are envisaged for confirmation of clinical cases during treatment campaigns and for certification of the interruption of transmission. Yaws testing requires both treponemal (trep) and non-treponemal (non-trep) assays for diagnosis of current infection. We evaluate a sequential testing strategy (using a treponemal RDT before a trep/non-trep RDT) in terms of cost and cost-effectiveness, relative to a single-assay combined testing strategy (using the trep/non-trep RDT alone), for two use cases: individual diagnosis and community surveillance...
October 2017: PLoS Neglected Tropical Diseases
https://www.readbyqxmd.com/read/29055866/high-diversity-of-human-parechovirus-including-novel-types-in-stool-samples-from-ghanaian-children
#20
Silke Graul, Sindy Böttcher, Daniel Eibach, Ralf Krumkamp, Julia Käsmaier, Yaw Adu-Sarkodie, Jürgen May, Egbert Tannich, Marcus Panning
BACKGROUND: Little is known on human parechovirus (HPeV) infections in Africa. OBJECTIVES: We aimed to determine the prevalence, genetic diversity, and association with diarrhea of HPeV in Ghanaian children. STUDY DESIGN: A total of 682 stool samples from a pediatric case-control study on causes of diarrhea collected in 2007-2008 were used. Laboratory analysis included HPeV real-time RT-PCR and sequencing partial viral protein (VP) 1 gene region of HPeV...
October 18, 2017: Journal of Clinical Virology: the Official Publication of the Pan American Society for Clinical Virology
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