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Martin Härter, Birgit Watzke, Anne Daubmann, Karl Wegscheider, Hans-Helmut König, Christian Brettschneider, Sarah Liebherz, Daniela Heddaeus, Maya Steinmann
Guidelines recommend stepped and collaborative care models (SCM) for depression. We aimed to evaluate the effectiveness of a complex guideline-based SCM for depressed patients. German primary care units were cluster-randomised into intervention (IG) or control group (CG) (3:1 ratio). Adult routine care patients with PHQ-9 ≥ 5 points could participate and received SCM in IG and treatment as usual (TAU) in CG. Primary outcome was change in PHQ-9 from baseline to 12 months (hypothesis: greater reduction in IG)...
June 20, 2018: Scientific Reports
Sevgi Kurt Yazar, Erkan Yüce, Merdan Serin, Memet Yazar, Zeliha Gül, Fatih Irmak, Serhat Selami Şirvan
BACKGROUND: The goals of tracheostomy scar revision are filling of the depressed area, providing easy sliding of skin over the trachea. There are various techniques described to correct this situation. In this article, a modification of split sternocleidomastoid (SCM) muscle flap used in the correction of posttracheostomy defects is described. METHODS: Thirteen patients who had depressed scars after tracheostomy are included in this study. The mean patient age was 44 years (range, 27-56 years)...
June 19, 2018: Annals of Plastic Surgery
Máté Durst, Katalin Könczöl, Tamás Balázsa, Mark D Eyre, Zsuzsanna E Tóth
BACKGROUND/OBJECTIVES: Dysfunction in reward-related aspects of feeding, and consequent overeating in humans, is a major contributor to obesity. Intrauterine undernutrition and overnutrition are among the predisposing factors, but the exact mechanism of how overeating develops is still unclear. Consummatory behavior is regulated by the medial shell (mSh) of the accumbens nucleus (Nac) through direct connections with the rostral part of the lateral hypothalamic area (LHA). Our aim was to investigate whether an altered Nac-LHA circuit may underlie hyperphagic behavior...
June 15, 2018: International Journal of Obesity: Journal of the International Association for the Study of Obesity
Mayadhar Barik, Pravash R Mishra, Ashok Kumar Mohapatra
Aim: Split cord malformation (SCM) is associated with extensive vertebral fusions (Klippel-Feil anomaly). In light of previous embryological theories and recent research findings, we attempt to document the origin of split cord, and vertebral fusions involvement of spectrum of genes is necessary to know better the etiopathogenesis of SCM and its associated diseases. Materials and Methods: We used the various databases such as PubMed/MEDLINE, Cochrane Review, Hinari, and Google Scholar for the recently published medical literature...
January 2018: Journal of Pediatric Neurosciences
Pedro Pedrosa Rebouças Filho, Solon Alves Peixoto, Raul Victor Medeiros da Nóbrega, D Jude Hemanth, Aldisio Gonçalves Medeiros, Arun Kumar Sangaiah, Victor Hugo C de Albuquerque
According to the American Cancer Society, melanoma is one of the most common types of cancer in the world. In 2017, approximately 87,110 new cases of skin cancer were diagnosed in the United States alone. A dermatoscope is a tool that captures lesion images with high resolution and is one of the main clinical tools to diagnose, evaluate and monitor this disease. This paper presents a new approach to classify melanoma automatically using structural co-occurrence matrix (SCM) of main frequencies extracted from dermoscopy images...
June 4, 2018: Computerized Medical Imaging and Graphics: the Official Journal of the Computerized Medical Imaging Society
Céline Pichon, Nicolas Suaud, Carine Duhayon, Nathalie Guihéry, Jean-Pascal Sutter
A cyano-bridged Fe(II)-Cr(III) single-chain magnet designed to ensure a parallel orientation of the axial anisotropy of the building units is reported. This ferromagnetic chain compound consists of a pentagonal bipyramid Fe(II) complex with Ising-type anisotropy and a dicyanide Cr(III) complex interlinked through their apical positions. It is characterized by an energy gap for the magnetization reversal of Δeff / kB = 113 K and exhibits magnetic hysteresis with a coercive field of 1400 Oe at 2 K which positions this compound among the very few examples of SCMs with spin reversal barriers above 100 K...
June 11, 2018: Journal of the American Chemical Society
Silvan F A Smulders, Eric L L Soetens, Maurits W van der Molen
This study examined age-related differences in sequential conflict modulation (SCM), elicited in three tasks requiring the inhibition of pre-potent responses; a Simon task, an S-R compatibility (SRC) task and a hybrid Choice-reaction/NoGo task. The primary focus was on age-related changes in performance changes following a conflict trial. A secondary aim was to assess whether SCM follows different developmental trajectories depending on the type of conflict elicited by the tasks. The tasks were presented to three different groups of participants with an age range between 7- to 25-years-one group of participants for each task...
2018: Frontiers in Psychology
Mahjoob Aghamohammadi, Denis Haine, David F Kelton, Herman W Barkema, Henk Hogeveen, Gregory P Keefe, Simon Dufour
Mastitis imposes considerable and recurring economic losses on the dairy industry worldwide. The main objective of this study was to estimate herd-level costs incurred by expenditures and production losses associated with mastitis on Canadian dairy farms in 2015, based on producer reports. Previously, published mastitis economic frameworks were used to develop an economic model with the most important cost components. Components investigated were divided between clinical mastitis (CM), subclinical mastitis (SCM), and other costs components (i...
2018: Frontiers in Veterinary Science
Mateus Tomaz Augusto, Juliete Melo Diniz, Fernando Luiz Rolemberg Dantas, Matheus Fernandes de Oliveira, José Marcus Rotta, Ricardo Vieira Botelho
INTRODUCTION: Spondylotic cervical myelopathy (SCM) is a common cause of spinal-related disability in the elderly. The assessment of this disability is a challenging task and depends on the subjective evaluation of the investigator. As a widespread used scale, the modified scale of the Japanese Association of Orthopedics (mJOA) should be translated and culturally adapted in the Brazilian Portuguese language (mJOA-Br) to provide its clinical and research use. OBJECTIVE: This study aims to do translation, transcultural adaptation and validation of the mJOA, into Brazilian Portuguese language...
June 1, 2018: World Neurosurgery
Kewu Wang, Shengxiang Xiao, Yongtao Ji, Yuqiu Fang
This paper presents a design of multifunctional portable automated external defibrillator based on STM32F103VC SCM. The defibrillator mainly realizes the defibrillation and ECG analysis function, and according to the clinical actual need, increases information storage and transmission function, query of local records, the function of synchronous LCD display and voice prompt in the defibrillation process. The device uses the defibrillating electrodes to measure body resistance, ECG and so on. We detailedly researched and achieved the discharge module of biphasic defibrillation apparatus based on the damping of two order discharge circuit, and finished the real-time LCD display and voice prompt modules of defibrillation information based on the control of PIC24FJ256DA210 chip...
January 30, 2018: Zhongguo Yi Liao Qi Xie za Zhi, Chinese Journal of Medical Instrumentation
Chadwick Debison-Larabie, Bernadette A Murphy, Michael W R Holmes
This study examined sex differences in head kinematics and neck muscle activity during sudden head perturbations. Sixteen competitive ice hockey players participated. Three muscles were monitored bilaterally using surface electromyography: sternocleidomastoid (SCM), scalene (SCL) and splenius capitis (SPC). Head and thorax kinematics were measured. Head perturbations were induced by the release of a 1.5kg weight, attached to a wire wrapped around an adjustable pulley secured to the participant's head. Perturbations were delivered in 4 directions (flexion, extension, right and left lateral bend)...
May 29, 2018: Journal of Applied Biomechanics
Taisuke Kondo, Yuuki Imura, Shunsuke Chikuma, Sana Hibino, Setsuko Omata-Mise, Makoto Ando, Takashi Akanuma, Mana Iizuka, Ryota Sakai, Rimpei Morita, Akihiko Yoshimura
Adoptive T cell therapy is an effective strategy for cancer immunotherapy. However, infused T cells frequently become functionally exhausted, and consequently offer a poor prognosis after transplantation into patients. Adoptive transfer of tumor antigen-specific stem cell memory T (TSCM ) cells is expected to overcome this shortcoming since TSCM cells are close to naïve T cells, but are also highly proliferative, long-lived, and produce a large number of effector T cells in response to antigen stimulation...
May 23, 2018: Cancer Science
Esmaeil Ebrahimie, Faezeh Ebrahimi, Mansour Ebrahimi, Sarah Tomlinson, Kiro R Petrovski
Sub-clinical mastitis (SCM) affects milk composition. In this study, we hypothesise that large-scale mining of milk composition features by pattern recognition models can identify the best predictors of SCM within the milk composition features. To this end, using data mining algorithms, we conducted a large-scale and longitudinal study to evaluate the ability of various milk production parameters as indicators of SCM. SCM is the most prevalent disease of dairy cattle, causing substantial economic loss for the dairy industry...
May 2018: Journal of Dairy Research
M Pylkkönen, A Tolvanen, C Hublin, J Kaartinen, K Karhula, S Puttonen, M Sihvola, M Sallinen
Education is a frequently recommended remedy for driver sleepiness in occupational settings, although not many studies have examined its usefulness. To date, there are no previous on-road randomized controlled trials investigating the benefits of training on sleepiness among employees working in road transport. To examine the effects of an educational intervention on long-haul truck drivers' sleepiness at the wheel, amount of sleep between work shifts, and use of efficient sleepiness countermeasures (SCM) in association with night and non-night shift, a total of 53 truck drivers operating from southern Finland were allocated into an intervention and a control group using a stratified randomization method (allocation ratio for intervention and control groups 32:21, respectively)...
May 18, 2018: Accident; Analysis and Prevention
Hasan Demirhan, Bahtiyar Hamit, Özgür Yiğit
OBJECTIVE: Cervical vestibular-evoked myogenic potentials (cVEMPs) are short-latency vestibulocollic reflexes. The damage on any point of the vestibulocollic reflex pathway could affect the cVEMPs. Whether neck dissection has an effect on the sacculocollic pathway, and consequently on cVEMPs, remains unexplored. The aim of this study was to evaluate the cVEMP findings in patients with functional neck dissection without vestibular symptoms. PATIENTS AND METHODS: This cross-sectional study design, 20 patients who had undergone unilateral neck dissection with sparing of the accessory nerve, SCM and internal jugular vein, were included...
June 2018: Journal of the National Medical Association
Cameron J Lacey, Kit Doudney, Paul G Bridgman, Peter M George, Roger T Mulder, Julie J Zarifeh, Bridget Kimber, Murray J Cadzow, Michael A Black, Tony R Merriman, Klaus Lehnert, Vivienne M Bickley, John F Pearson, Vicky A Cameron, Martin A Kennedy
The pathophysiology of stress cardiomyopathy (SCM), also known as takotsubo syndrome, is poorly understood. SCM usually occurs sporadically, often in association with a stressful event, but clusters of cases are reported after major natural disasters. There is some evidence that this is a familial condition. We have examined three possible models for an underlying genetic predisposition to SCM. Our primary study cohort consists of 28 women who suffered SCM as a result of two devastating earthquakes that struck the city of Christchurch, New Zealand, in 2010 and 2011...
May 15, 2018: Scientific Reports
Kristina A Monteiro, Karl Dietrich, Jeffrey Borkan, Luba Dumenco, Allan R Tunkel, Richard Dollase, Paul George
BACKGROUND AND OBJECTIVES: The Warren Alpert Medical School of Brown University (AMS) recently implemented a novel dual degree MD-ScM program in primary care and population medicine (PC-PM) that enrolls up to 24 of its nearly 144 yearly matriculants. The overarching goal of this track is to train medical students to become physician leaders who focus on issues in population medicine within primary care. METHODS: We conducted a baseline assessment of the students enrolled in this parallel track in comparison to our traditional students to identify characteristics of and group differences between students in the PC-PM program and traditional students...
May 2018: Family Medicine
Susan T Fiske
Two dimensions persist in social cognition, whether people are making sense of individuals or groups. The Stereotype Content Model terms the basic dimensions perceived warmth (trustworthiness, friendliness) and competence (capability, assertiveness). Measured reliably and validly, these Big Two dimensions converge across methods: survey, cultural, laboratory, and biobehavioral approaches. Generality across place, levels, and time further support the framework. Parallel pairs have emerged repeatedly over the history of psychology and in current theories...
April 2018: Current Directions in Psychological Science
Md Samrat Alam, Drew Gorman-Lewis, Ning Chen, Shannon L Flynn, Yong Ok, Kurt Konhauser, Daniel S Alessi
While numerous studies have investigated metal uptake from solution by biochar, few of these have developed a mechanistic understanding of the adsorption reactions that occur at the biochar surface. In this study, we explore a combined modeling and spectroscopic approaches for the first time to describe the molecular level adsorption of Ni(II) and Zn(II) to biochar using five types of biochar. Following thorough characterization, potentiometric titrations were carried out to measure the proton (H+) reactivity of each biochar, and the data was used to develop protonation models...
May 10, 2018: Environmental Science & Technology
Joanna Coast, Cara Bailey, Rosanna Orlando, Kathy Armour, Rachel Perry, Louise Jones, Philip Kinghorn
BACKGROUND AND OBJECTIVES: Adaptive preferences occur when people subconsciously alter their views to account for the possibilities available to them. Adaptive preferences may be problematic where these views are used in resource allocation decisions because they may lead to underestimation of the true benefits of providing services. This research explored the nature and extent of both adaptation (changing to better suit the context) and adaptive preferences (altering preferences in response to restricted options) in individuals approaching the end of life (EoL)...
May 9, 2018: Patient
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