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https://www.readbyqxmd.com/read/28298044/a-novel-method-of-lengthening-the-accessory-nerve-for-direct-coaptation-during-nerve-repair-and-nerve-transfer-procedures
#1
R Shane Tubbs, Andrés A Maldonado, Yolanda Stoves, Fabian N Fries, Rong Li, Marios Loukas, Rod J Oskouian, Robert J Spinner
OBJECTIVE The accessory nerve is frequently repaired or used for nerve transfer. The length of accessory nerve available is often insufficient or marginal (under tension) for allowing direct coaptation during nerve repair or nerve transfer (neurotization), necessitating an interpositional graft. An attractive maneuver would facilitate lengthening of the accessory nerve for direct coaptation. The aim of the present study was to identify an anatomical method for such lengthening. METHODS In 20 adult cadavers, the C-2 or C-3 connections to the accessory nerve were identified medial to the sternocleidomastoid (SCM) muscle and the anatomy of the accessory nerve/cervical nerve fibers within the SCM was documented...
March 3, 2017: Journal of Neurosurgery
https://www.readbyqxmd.com/read/28296812/pedicled-vascularized-clavicular-graft-for-anterior-cervical-arthrodesis-cadaveric-feasibility-study-technique-description-and-case-report
#2
Michael A Bohl, Michael A Mooney, Joshua S Catapano, Kaith K Almefty, Mark C Preul, Steve W Chang, U Kumar Kakarla, Edward M Reece, Jay D Turner, Randall W Porter
STUDY DESIGN: Cadaveric feasibility study. OBJECTIVES: To assess the anatomic and technical feasibility of rotating a clavicular segment on a sternocleidomastoid muscle (SCM) pedicle into the ventral cervical spine using a cadaveric model and to provide the first clinical case description of performing this procedure. SUMMARY OF BACKGROUND DATA: Reconstruction of the anterior cervical spine in patients with a high risk of pseudoarthrosis may require the use of a vascularized bone graft (VBG)...
March 14, 2017: Spine
https://www.readbyqxmd.com/read/28291021/laser-patterning-of-highly-conductive-flexible-circuits
#3
Seok Young Ji, Muhammed Ajmal Chathanchira, Taehun Kim, Won Seok Chang, Seunghyun Baik
There has been considerable attention in highly conductive flexible adhesive (CFA) materials as electrodes and interconnectors for future flexible electronic devices. However, the patterning technology still needs to be developed to construct micro-scale electrodes and circuits. Here we developed the selective laser sintering technology where the pattering and curing were accomplished simultaneously without making additional masks. The CFA was composed of micro-scale Ag flakes, multiwalled carbon nanotubes decorated with Ag nanoparticles, and nitrile-butadiene-rubber matrix...
March 14, 2017: Nanotechnology
https://www.readbyqxmd.com/read/28273592/distribution-of-picoplankton-in-the-northeastern-south-china-sea-with-special-reference-to-the-effects-of-the-kuroshio-intrusion-and-the-associated-mesoscale-eddies
#4
Jiajun Li, Xin Jiang, Gang Li, Zhiyou Jing, Linbin Zhou, Zhixin Ke, Yehui Tan
We investigated picoplankton distribution patterns and environmental variables along an east-to-west transect in the northeastern South China Sea (SCS) during late winter 2016, giving us the opportunity to examine the impacts of the Kuroshio intrusion and the associated eddies. The results indicated that the subsurface (50-75m) phytoplankton biomass chlorophyll (Chl a) maximum (SCM) disappeared and was replaced by higher Chl a in the middle part of the transect due to the impacts of the Kuroshio intrusion and mesoscale eddies...
March 3, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/28263791/accuracy-of-point-of-care-focused-echocardiography-in-predicting-outcome-of-resuscitation-in-cardiac-arrest-patients-a-systematic-review-and-meta-analysis
#5
REVIEW
Po-Yang Tsou, Jeantte Kurbedin, Yueh-Sheng Chen, Eric H Chou, Meng-Tse Gabriel Lee, Matthew Chien-Hung Lee, Matthew Huei-Ming Ma, Shyr-Chyr Chen, Chien-Chang Lee
OBJECTIVE: We aim to summarize current evidence on the value of Point-of-Care (POC) focused echocardiography in the assessment of short-term survival in patients with cardiac arrest. METHODS: PubMed and EMBASE were searched from inception to July 2016 for eligible studies that evaluated the utility of POC echocardiography in patients with cardiac arrest. Modified QUADAS was used to appraise the quality of included studies. A random-effect bivariate model and a hierarchical summary receiving operating curve were used to summarize the performance characteristics of focused echocardiography...
March 2, 2017: Resuscitation
https://www.readbyqxmd.com/read/28257285/population-pharmacokinetics-of-vancomycin-in-chinese-pediatric-patients%C3%A2
#6
Taotao Liu, Chen Deng, Daohai Cheng, Tianyan Zhou, Hua Lu, Wenxing Wei, Wei Lu
OBJECTIVE: This study was conducted to develop a population pharmacokinetic (PopPK) model for vancomycin and to detect the significant covariates that influence the PopPKs to facilitate individualized therapy for Chinese pediatric patients. METHODS: Patients ≤ 10 years old who received vancomycin for ≥ 72 hours between 2007 and 2010 were analyzed using a nonlinear mixed-effects modeling approach (-NONMEM). A one-compartment model with first-order elimination was chosen to depict the data...
March 3, 2017: International Journal of Clinical Pharmacology and Therapeutics
https://www.readbyqxmd.com/read/28250970/air-liquid-interface-enhances-oxidative-phosphorylation-in-intestinal-epithelial-cell-line-ipec-j2
#7
Sonja Klasvogt, Werner Zuschratter, Anke Schmidt, Andrea Kröber, Sandra Vorwerk, Romina Wolter, Berend Isermann, Klaus Wimmers, Hermann-Josef Rothkötter, Constanze Nossol
The intestinal porcine epithelial cell line IPEC-J2, cultured under the air-liquid interface (ALI) conditions, develops remarkable morphological characteristics close to intestinal epithelial cells in vivo. Improved oxygen availability has been hypothesised to be the leading cause of this morphological differentiation. We assessed oxygen availability in ALI cultures and examined the influence of this cell culture method on glycolysis and oxidative phosphorylation in IPEC-J2 using the submerged membrane culture (SMC) and ALI cultures...
2017: Cell Death Discovery
https://www.readbyqxmd.com/read/28247108/lateral-lipomyelomeningocele-of-the-hemicord-with-split-cord-malformation-type-i-revealed-by-3d-heavily-t2-weighted-mr-imaging
#8
Nobuya Murakami, Takato Morioka, Masako Ichiyama, Ryoko Nakamura, Nobuko Kawamura
BACKGROUND: Lipomyelomeningocele (LMMC) is defined by a low-lying tethered spinal cord protruding posteriorly from the spinal canal and terminating in a lipomatous mass in the subcutaneous meningeal sac. The coexistence of LMMC with split cord malformation (SCM) is rare. CLINICAL PRESENTATION: We report on a patient with laterally protruded LMMC arising from the hemicord of SCM type I. Direct coronal and axial views (instead of sagittal views) of 3D heavily T2-weighted MR imaging (3D-hT2WI) clearly demonstrated the topographical relationship between both of the hemicords, the bony septum, and nerve roots in the right subcutaneous meningeal sac...
February 28, 2017: Child's Nervous System: ChNS: Official Journal of the International Society for Pediatric Neurosurgery
https://www.readbyqxmd.com/read/28236068/positional-plagiocephaly-is-associated-with-sternocleidomastoid-muscle-activation-in-healthy-term-infants
#9
Amy Leung, Allison Mandrusiak, Pauline Watter, John Gavranich, Leanne Johnston
PURPOSE: To explore the relationship between sternocleidomastoid activation and positional plagiocephaly in healthy full term infants. METHODS: Participants were 82 infants from a regionally based-longitudinal study of infant development. Sternocleidomastoid (SCM) activation was assessed using active head-righting responses of body-on-head with and against gravity and head-on-body against gravity at 3, 6 and 9 weeks. Plagiocephaly was assessed using the Modified Cranial Vault Asymmetry Index (mCVAI) at 9 weeks...
February 24, 2017: Child's Nervous System: ChNS: Official Journal of the International Society for Pediatric Neurosurgery
https://www.readbyqxmd.com/read/28229590/impacts-of-cross-linkers-on-biological-effects-of-mesoporous-silica-nanoparticles
#10
Yi-Ping Chen, Si-Han Wu, I-Chih Chen, Chien-Tsu Chen
Chemically synthesized cross-linkers play decisive roles in variable cargos attached to nanoparticles (NPs). Previous studies reported that surface properties, such as the size, charge, and surface chemistry, are particularly important determinants influencing the biological fate and actions of NPs and cells. Recent studies also focused on the relationship of serum proteins with the surface properties of NPs (also called the protein corona), which is recognized as a key factor in determining the cytotoxicity and biodistribution...
March 7, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/28229244/prevalence-and-correlates-of-use-of-safer-conception-methods-in-a-prospective-cohort-of-ugandan-hiv-affected-couples-with-fertility-intentions
#11
Glenn J Wagner, Sebastian Linnemayr, Kathy Goggin, Deborah Mindry, Jolly Beyeza-Kashesya, Sarah Finocchario-Kessler, Eric Robinson, Josephine Birungi, Rhoda K Wanyenze
We examined the prevalence and correlates of safer conception methods (SCM) use in HIV-affected couples with fertility intentions. A prospective cohort of 400 HIV clients in Uganda who had fertility intentions with their partner was surveyed every 6 months for 24 months. Logistic regression analysis was used to determine individual, relationship and provider level predictors of SCM use. Over one-third (35%) reported any use of timed unprotected intercourse (TUI) during the study; use of other SCM was rare...
February 22, 2017: AIDS and Behavior
https://www.readbyqxmd.com/read/28228099/impact-of-adding-additional-providers-to-resident-workload-and-the-resident-experience-on-a-medical-consultation-rotation
#12
Michele Fang, Eric Linson, Manish Suneja, Ethan F Kuperman
BACKGROUND: Excellence in Graduate Medical Education requires the right clinical environment with an appropriate workload where residents have enough patients to gain proficiency in medicine with optimal time for reflection. The Accreditation Council for Graduate Medical Education (ACGME) has focused more on work hours rather than workload; however, high resident workload has been associated with lower resident participation in education and fatigue-related errors. Recognizing the potential risks associated with high resident workload and being mindful of the costs of reducing resident workload, we sought to reduce residents' workload by adding an advanced practice provider (APP) to the surgical comanagement service (SCM) and study its effect on resident satisfaction and perceived educational value of the rotation...
February 22, 2017: BMC Medical Education
https://www.readbyqxmd.com/read/28221164/positive-and-negative-cues-for-modulating-neurite-dynamics-and-receptor-expression
#13
Melissa Wrobel, Harini Gayathari Sundararaghavan
Many current peripheral nerve repair strategies focus on delivering positive, growth promoting cues (e.g. extracellular matrix, ECM) while eliminating negative, growth inhibiting cues (e.g. chondroitin sulfate proteoglycans, CSPGs) at the injury site. We hypothesized that recapitulating the positive and negative cues of the peripheral nerve injury microenvironment would improve regeneration. First, we tested the effects of a characteristic CSPG, Chondroitin Sulfate A (CSA) on neurite dynamics of dissociated chick embryo dorsal root ganglion (DRG) neurons using time lapse video microscopy...
February 21, 2017: Biomedical Materials
https://www.readbyqxmd.com/read/28220925/slow-relaxation-of-the-magnetization-observed-in-an-antiferromagnetically-ordered-phase-for-scm-based-two-dimensional-layered-compounds
#14
Koichi Kagesawa, Yuki Nishimura, Hiroki Yoshida, Brian K Breedlove, Masahiro Yamashita, Hitoshi Miyasaka
Two-dimensional layered compounds with different counteranions, [{Mn(salen)}4C6](BF4)2·2(CH3OH) (1) and [{Mn(salen)}4C6](PF6)2·2(CH3OH) (2) (salen(2-) = N,N'-bis(salicylideneiminato), C6(2-) = C6H12(COO)2(2-)), were synthesized by assembling [Mn(salen)(H2O)]X (X(-) = BF4(-) and PF6(-)) and C6H12(CO2(-))2 (C6(2-)) in a methanol/2-propanol medium. The compounds have similar structures, which are composed of Mn(salen) out-of-plane dimers bridged by μ(4)-type C6(2-) ions, forming a brick-wall-type network of [-{Mn2}-OCO-] chains alternately connected via C6H12 linkers of C6(2-) moieties...
February 21, 2017: Dalton Transactions: An International Journal of Inorganic Chemistry
https://www.readbyqxmd.com/read/28216141/encapsulated-follicular-variant-of-papillary-thyroid-carcinoma-noninvasive-follicular-thyroid-neoplasm-with-papillary-like-nuclear-features-with-spindle-cell-metaplasia-case-report-and-review-of-literature
#15
Mohamed Rizwan Haroon Al Rasheed, Andres Acosta, Gabor Tarjan
Spindle cell lesions of the thyroid are rare overall, and span a wide clinical spectrum that ranges from spindle cell metaplasia (SCM(1)) to anaplastic carcinoma. Their differentiation is only seldom straightforward, and usually requires the integration of the clinical, histological and immunohistochemical data. Only a handful of publications have described cases of SCM in the thyroid and we add to that literature by reporting a unique case of encapsulated follicular variant of papillary thyroid carcinoma/noninvasive follicular thyroid neoplasm with papillary-like nuclear features with SCM...
January 5, 2017: Pathology, Research and Practice
https://www.readbyqxmd.com/read/28197917/sumo-in-drosophila-development
#16
Joseph Cao, Albert J Courey
The ubiquitin -like protein SUMO is conjugated covalently to hundreds of target proteins in organisms throughout the eukaryotic domain. Genetic and biochemical studies using the model organism Drosophila melanogaster are beginning to reveal many essential functions for SUMO in cell biology and development. For example, SUMO regulates multiple signaling pathways such as the Ras/MAPK, Dpp, and JNK pathways. In addition, SUMO regulates transcription through conjugation to many transcriptional regulatory proteins, including Bicoid, Spalt , Scm, and Groucho...
2017: Advances in Experimental Medicine and Biology
https://www.readbyqxmd.com/read/28197279/a-sudden-change-of-heart-a-case-of-rapidly-reversed-stress-cardiomyopathy-in-a-critically-ill-patient
#17
Michael I Brener, Ali R Keramati, Marek A Mirski, Oscar H Cingolani
We report the case of a 79-year-old woman who presented to our hospital for elective removal of an infratentorial meningioma and suffered a periprocedural cardiac arrest. Shortly after uncomplicated induction of anesthesia prior to the surgery, the patient became hypotensive and bradycardic, culminating ultimately in a cardiac arrest with pulseless electrical activity. Return of spontaneous circulation occurred within 90 seconds of arrest, but the patient remained dependent on maximal doses of epinephrine and dopamine for hemodynamic support...
June 2016: Cardiology Research
https://www.readbyqxmd.com/read/28190955/multi-level-correlates-of-safer-conception-methods-awareness-and-attitudes-among-ugandan-hiv-clients-with-fertility-intentions
#18
Glenn J Wagner, Mahlet A Woldetsadik, Jolly Beyeza-Kashesya, Kathy Goggin, Deborah Mindry, Sarah Finocchario-Kessler, Sarah Khanakwa, Rhoda K Wanyenze
Many people living with HIV desire childbearing, but low cost safer conception methods (SCM) such as timed unprotected intercourse (TUI) and manual self-insemination (MSI) are rarely used. We examined awareness and attitudes towards SCM, and the correlates of these constructs among 400 HIV clients with fertility intentions in Uganda. Measures included awareness, self-efficacy, and motivation regarding SCM, as well as demographics, health management, partner and provider characteristics. Just over half knew that MSI (53%) and TUI (51%) reduced transmission risk during conception, and 15% knew of sperm washing and pre-exposure prophylaxis...
March 2016: African Journal of Reproductive Health
https://www.readbyqxmd.com/read/28180088/human-case-of-bacteremia-caused-by-streptococcus-canis-sequence-type-9-harboring-the-scm-gene
#19
Daisuke Taniyama, Yoshihiko Abe, Tetsuya Sakai, Takahide Kikuchi, Takashi Takahashi
Streptococcus canis (Sc) is a zoonotic pathogen that is transferred mainly from companion animals to humans. One of the major virulence factors in Sc is the M-like protein encoded by the scm gene, which is involved in anti-phagocytic activities, as well as the recruitment of plasminogen to the bacterial surface in cooperation with enolase, and the consequent enhancement of bacterial transmigration and survival. This is the first reported human case of uncomplicated bacteremia following a dog bite, caused by Streptococcus canis harboring the scm gene...
2017: IDCases
https://www.readbyqxmd.com/read/28178161/longitudinal-follow-up-of-muscle-echotexture-in-infants-with-congenital-muscular-torticollis
#20
Ching-Fang Hu, Tieh-Cheng Fu, Chung-Yao Chen, Carl Pai-Chu Chen, Yu-Ju Lin, Chih-Chin Hsu
Unilateral fibrous contracture of the sternocleidomastoid (SCM) muscle is the major pathophysiology in infants with congenital muscular torticollis (CMT). Physical examination is not always sufficient to detect minimal muscle fibrosis in involved SCM muscles.A prospective study for SCM muscle fibrosis in CMT infants by quantifying echotexture and muscle thickness during the course of treatment is highlighted in the study.Convenience samples of 21 female and 29 male infants with CMT, who were 1 to 12 months old, underwent physiotherapy for at least 3 months and were followed for 4...
February 2017: Medicine (Baltimore)
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