Kaitlyn J Nielson, Ross Rowsey, Surendra Dasari, William R Sukov, Benjamin R Kipp, Aditya Raghunathan, Rumeal D Whaley, Kingsley Ebare, Melissa L Stanton, Jordan P Reynolds, Vidit Sharma, R Houston Thompson, Stephen A Boorjian, Bradley C Leibovich, Loren Herrera Hernandez, Rafael E Jimenez, John C Cheville, Sounak Gupta
Mucinous tubular and spindle cell carcinoma (MTSCC) shows significant overlap with papillary renal cell carcinoma (PRCC), and harbor recurrent copy-number alterations (CNA). We evaluated 16 RCC with features suggestive of MTSCC using chromosomal microarrays. The cohort was comprised of 8 females and males, each, with an age range of 33-79 years (median, 59), and a tumor size range of 3.4-15.5 cm (median, 5.0). Half the tumors were high-grade (8/16, 50%) with features such as necrosis, marked cytologic atypia, and sarcomatoid differentiation, and 5/16 (31%) were high stage (≥pT3a)...
April 12, 2024: Human Pathology