D F Du Toit, J J Heydenrych, B Smit, T Zuurmond, G Louw, L Laker, D Els, A Weideman, S Wolfe-Coote, L B Du Toit
In this study we evaluated the endocrine, biochemical, and haematological derangements as well as pancreatic and histological changes of the bonemarrow in the primate following external fractionated subtotal marrow irradiation without bonemarrow reconstitution. The irradiation was administered in preparation for pancreatic transplantation. Two groups of animals (ten in each group) received 800 rad (8 Gy) and 1,000 rad (10 Gy) respectively over 4 to 5 weeks. A maximum of 200 rads (2 Gy) were administered weekly as photons from a 6 MV linear accelerator...
January 1987: Journal of Surgical Oncology