keyword
MENU ▼
Read by QxMD icon Read
search

ionizing radiation exposure

keyword
https://www.readbyqxmd.com/read/28648966/ultra-low-radiation-exposure-during-flexible-ureteroscopy-in-nephrolithiasis-patients-how-far-can-we-go
#1
Simon Hein, Martin Schoenthaler, Konrad Wilhelm, Daniel Schlager, Werner Vach, Ulrich Wetterauer, Arkadiusz Miernik
OBJECTIVES: To evaluate the feasibility and clinical performance of a novel surgeon technique and protocol targeting ultra-low fluoroscopy usage in retrograde intrarenal surgery (RIRS). METHODS: All RIRS procedures between 2009 and 2015 for 10-20-mm renal calculi performed by the same two experienced urologists were eligible. All procedures were performed using a highly standardized step by step RIRS technique. This technique was modified by the ultra-low radiation exposure RIRS protocol: herein as much as possible of the standardized steps were performed without radiation control targeting ultra-low fluoroscopy usage...
June 22, 2017: Urology
https://www.readbyqxmd.com/read/28648410/the-great-unknown-a-systematic-literature-review-about-risk-associated-with-intraoperative-imaging-during-orthopaedic-surgeries
#2
REVIEW
Amir Matityahu, Ryan K Duffy, Sabine Goldhahn, Alexander Joeris, Peter H Richter, Florian Gebhard
INTRODUCTION: Modern techniques in orthopaedic surgery using minimally invasive procedures, and increased use of fluoroscopic imaging present a potential increased risk to surgeons due to ionizing radiation exposure. This article is a systematic review of recent literature on radiation exposure of orthopaedic surgeons. MATERIALS AND METHODS: Pubmed and Cochrane searches were performed on intraoperative radiation exposure covering English and German articles published between 1...
April 21, 2017: Injury
https://www.readbyqxmd.com/read/28646455/human-nucleus-pulposus-intervertebral-disc-cells-becoming-senescent-using-different-treatments-exhibit-a-similar-transcriptional-profile-of-catabolic-and-inflammatory-genes
#3
Sotiris-Spyros Vamvakas, Eleni Mavrogonatou, Dimitris Kletsas
PURPOSE: Chronic low back pain has been associated with intervertebral disc (IVD) degeneration, which is characterized by the accumulation of extracellular matrix (ECM)-degrading proteases and inflammatory molecules in the degenerate tissue. IVD degeneration could be the outcome of natural organismal ageing and/or of the exposure of the disc to cumulative stressful environmental stimuli and is accompanied by an increased population of senescent cells in the tissue. On the other hand, senescent cells are known to secrete proteolytic enzymes and inflammatory molecules, which can contribute to ECM catabolism...
June 23, 2017: European Spine Journal
https://www.readbyqxmd.com/read/28645672/percutaneous-pedicle-screw-placement-under-single-dimensional-fluoroscopy-with-a-designed-pedicle-finder-a-technical-note-and-case-series
#4
Fon-Yih Tsuang, Chia-Hsien Chen, Yi-Jie Kuo, Wei-Lung Tseng, Yuan-Shen Chen, Chin-Jung Lin, Chun-Jen Liao, Feng-Huei Lin, Chang-Jung Chiang
BACKGROUND CONTEXT: Minimally invasive spine surgery has become increasingly popular in clinical practice, and it offers patients the potential benefits of reduced blood loss, wound pain, and infection risk and also diminishes the loss of working time and length of hospital stay. However, surgeons require more intraoperative fluoroscopy and ionizing radiation exposure during minimally invasive spine surgery for localization, especially for guidance in instrumentation placement. In addition, computer navigation is not accessible in some facility-limited institutions...
June 20, 2017: Spine Journal: Official Journal of the North American Spine Society
https://www.readbyqxmd.com/read/28645457/diagnostic-medical-imaging-in-pediatric-patients-and-subsequent-cancer-risk
#5
REVIEW
David J Mulvihill, Sachin Jhawar, John B Kostis, Sharad Goyal
The use of diagnostic medical imaging is becoming increasingly more commonplace in the pediatric setting. However, many medical imaging modalities expose pediatric patients to ionizing radiation, which has been shown to increase the risk of cancer development in later life. This review article provides a comprehensive overview of the available data regarding the risk of cancer development following exposure to ionizing radiation from diagnostic medical imaging. Attention is paid to modalities such as computed tomography scans and fluoroscopic procedures that can expose children to radiation doses orders of magnitude higher than standard diagnostic x-rays...
June 20, 2017: Academic Radiology
https://www.readbyqxmd.com/read/28645274/buccal-mucosa-micronuclei-counts-in-relation-to-exposure-to-low-dose-rate-radiation-from-the-chornobyl-nuclear-accident-and-other-medical-and-occupational-radiation-exposures
#6
D Bazyka, S C Finch, I M Ilienko, O Lyaskivska, I Dyagil, N Trotsiuk, N Gudzenko, V V Chumak, K M Walsh, J Wiemels, M P Little, L B Zablotska
BACKGROUND: Ionizing radiation is a well-known carcinogen. Chromosome aberrations, and in particular micronuclei represent an early biological predictor of cancer risk. There are well-documented associations of micronuclei with ionizing radiation dose in some radiation-exposed groups, although not all. That associations are not seen in all radiation-exposed groups may be because cells with micronuclei will not generally pass through mitosis, so that radiation-induced micronuclei decay, generally within a few years after exposure...
June 23, 2017: Environmental Health: a Global Access Science Source
https://www.readbyqxmd.com/read/28638454/downregulation-of-mitochondrial-single-stranded-dna-binding-protein-ssbp1-induces-mitochondrial-dysfunction-and-increases-the-radiosensitivity-in-non-small-cell-lung-cancer-cells
#7
You Wang, Liu Hu, Ximei Zhang, Hong Zhao, Hui Xu, Yuehua Wei, Huangang Jiang, Conghua Xie, Yunfeng Zhou, Fuxiang Zhou
Radiotherapy is one of the major therapeutic strategies for human non-small cell lung cancer (NSCLC), but intrinsic radioresistance of cancer cells makes a further improvement of radiotherapy for NSCLC challenging. Mitochondrial function is frequently dysregulated in cancer cells for adaptation to the changes of tumor microenvironment after exposure to radiation. Therefore, targeting mitochondrial biogenesis and bioenergetics is an attractive strategy to sensitize cancer cells to radiation therapy. In this study, we found that downregulation of single-strand DNA-binding protein 1 (SSBP1) in H1299 cells was associated with inducing mitochondrial dysfunction and increasing radiosensitivity to ionizing radiation...
2017: Journal of Cancer
https://www.readbyqxmd.com/read/28638385/intercellular-communication-of-tumor-cells-and-immune-cells-after-exposure-to-different-ionizing-radiation-qualities
#8
REVIEW
Sebastian Diegeler, Christine E Hellweg
Ionizing radiation can affect the immune system in many ways. Depending on the situation, the whole body or parts of the body can be acutely or chronically exposed to different radiation qualities. In tumor radiotherapy, a fractionated exposure of the tumor (and surrounding tissues) is applied to kill the tumor cells. Currently, mostly photons, and also electrons, neutrons, protons, and heavier particles such as carbon ions, are used in radiotherapy. Tumor elimination can be supported by an effective immune response...
2017: Frontiers in Immunology
https://www.readbyqxmd.com/read/28632552/comparative-study-of-c-arms-for-intraoperative-3-dimensional-imaging-and-navigation-in-minimally-invasive-spine-surgery-part-ii-radiation-exposure
#9
Jan-Helge Klingler, Ronen Sircar, Christian Scheiwe, Evangelos Kogias, Marie T Krüger, Christoph Scholz, Ulrich Hubbe
STUDY DESIGN: A radiation exposure study in vitro. OBJECTIVE: This study aimed to compare the radiation exposure of 2 different 3-dimensional (3D) C-arm devices on an anthropomorphic phantom. SUMMARY OF BACKGROUND DATA: Minimally invasive pedicle screw placement requires intraoperative imaging techniques for visualization of the unexposed spine. Mobile 3D C-arms compose a 3D image data set out of multiple successive fluoroscopic images. METHODS: We compared the 3D C-arm devices Siremobil Iso-C 3D (Siemens Sector Healthcare, Erlangen, Germany) and Vision FD Vario 3D (Ziehm Imaging, Nuremberg, Germany) regarding their radiation exposure...
July 2017: Clinical Spine Surgery
https://www.readbyqxmd.com/read/28632432/serum-micrornas-as-early-indicators-for-estimation-of-exposure-degree-in-response-to-ionizing-irradiation
#10
Wenjun Wei, Jinpeng He, Jufang Wang, Nan Ding, Bing Wang, Sulan Lin, Xurui Zhang, Junrui Hua, He Li, Burong Hu
Exposure to ionizing radiation from nuclear devices, spaceflights or terrorist attacks represents a major threat to human health and public security. After a radiological incident, noninvasive biomarkers that can facilitate rapid assessment of exposure risk in the early stages are urgently needed for optimal medical treatment. Serum microRNAs (miRNAs) are ideal biomarkers because they are stable in response to environmental changes, they are common among different species and are easily collected. Here, we performed miRNA PCR arrays to analyze miRNA expression profiles at 24 h postirradiation...
June 20, 2017: Radiation Research
https://www.readbyqxmd.com/read/28628668/dose-dependent-effects-of-gamma-radiation-on-the-early-zebrafish-development-and-gene-expression
#11
Selma Hurem, Leonardo Martín Martín, Dag Anders Brede, Eystein Skjerve, Rasoul Nourizadeh-Lillabadi, Ole Christian Lind, Terje Christensen, Vidar Berg, Hans-Christian Teien, Brit Salbu, Deborah Helen Oughton, Peter Aleström, Jan Ludvig Lyche
Ionizing radiation from natural sources or anthropogenic activity has the potential to cause oxidative stress or genetic damage in living organisms, through the ionization and excitation of molecules and the subsequent production of free radicals and reactive oxygen species (ROS). The present work focuses on radiation-induced biological effects using the zebrafish (Danio rerio) vertebrate model. Changes in developmental traits and gene expression in zebrafish were assessed after continuous external gamma irradiation (0...
2017: PloS One
https://www.readbyqxmd.com/read/28616425/medical-radiation-workers-knowledge-attitude-and-practice-to-protect-themselves-against-ionizing-radiation-in-tehran-province-iran
#12
Seyedeh Shohreh Alavi, Sima Taghizadeh Dabbagh, Mahya Abbasi, Ramin Mehrdad
BACKGROUND: Medical radiation workers are potentially at a risk of unwanted ionizing radiation exposures. This study assessed the radiation protection knowledge, attitude, and practice (RP-KAP) of health-care workers who are occupationally exposed to radiation regarding protecting themselves from radiation. MATERIALS AND METHODS: This study was cross-sectional in design and was carried out in 16 hospitals affiliated to the Tehran University of Medical Sciences between May and September 2014...
2017: Journal of Education and Health Promotion
https://www.readbyqxmd.com/read/28615014/are-physicians-aware-enough-of-patient-radiation-protection-results-from-a-survey-among-physicians-of-pavia-district-italy
#13
Francesca Campanella, Laura Rossi, Elio Giroletti, Piero Micheletti, Fabio Buzzi, Simona Villani
BACKGROUND: Radiological practices are the first anthropic sources of ionizing radiation exposure of the population. However, a review of recent publications underlines inadequate doctors' knowledge about doses imparted in medical practices and about patient protection that might explain unnecessary radiological prescriptions. We investigated the knowledge of the physicians of Pavia District (Italy) on the risk of radiation exposure. METHODS: A cross sectional study was performed involving the Medical Association of Pavia District...
June 14, 2017: BMC Health Services Research
https://www.readbyqxmd.com/read/28613990/different-sequences-of-fractionated-low-dose-proton-and-single-iron-radiation-induced-divergent-biological-responses-in-the-heart
#14
Sharath P Sasi, Xinhua Yan, Marian Zuriaga-Herrero, Hannah Gee, Juyong Lee, Raman Mehrzad, Jin Song, Jillian Onufrak, James Morgan, Heiko Enderling, Kenneth Walsh, Raj Kishore, David A Goukassian
Deep-space travel presents risks of exposure to ionizing radiation composed of a spectrum of low-fluence protons ((1)H) and high-charge and energy (HZE) iron nuclei (e.g., (56)Fe). When exposed to galactic cosmic rays, each cell in the body may be traversed by (1)H every 3-4 days and HZE nuclei every 3-4 months. The effects of low-dose sequential fractionated (1)H or HZE on the heart are unknown. In this animal model of simulated ionizing radiation, middle-aged (8-9 months old) male C57BL/6NT mice were exposed to radiation as follows: group 1, nonirradiated controls; group 2, three fractionated doses of 17 cGy (1)H every other day ((1)H × 3); group 3, three fractionated doses of 17 cGy (1)H every other day followed by a single low dose of 15 cGy (56)Fe two days after the final (1)H dose ((1)H × 3 + (56)Fe); and group 4, a single low dose of 15 cGy (56)Fe followed (after 2 days) by three fractionated doses of 17 cGy (1)H every other day ((56)Fe + (1)H × 3)...
June 14, 2017: Radiation Research
https://www.readbyqxmd.com/read/28612056/critical-appraisal-of-the-top-down-approach-for-vesicoureteral-reflux
#15
REVIEW
Ahmed Abdelhalim, Antoine E Khoury
Vesicoureteral reflux (VUR) has been linked to recurrent urinary tract infections (UTIs), renal scarring, hypertension, renal insufficiency and end-stage kidney disease. Different imaging strategies have been proposed to approach children presenting with UTI to sort out patients with significant VUR while minimizing patient morbidity, radiation exposure and financial burden. None of these imaging strategies is universally accepted. The"top-down approach" (TDA) aims at restricting the number of voiding cystourethrograms (VCUGs) and its associated morbidity while identifying patients with clinically-significant reflux...
June 2017: Investigative and Clinical Urology
https://www.readbyqxmd.com/read/28603525/modulating-both-tumor-cell-death-and-innate-immunity-is-essential-for-improving-radiation-therapy-effectiveness
#16
REVIEW
Qiuji Wu, Awatef Allouch, Isabelle Martins, Catherine Brenner, Nazanine Modjtahedi, Eric Deutsch, Jean-Luc Perfettini
Radiation therapy is one of the cornerstones of cancer treatment. In tumor cells, exposure to ionizing radiation (IR) provokes DNA damages that trigger various forms of cell death such as apoptosis, necrosis, autophagic cell death, and mitotic catastrophe. IR can also induce cellular senescence that could serve as an additional antitumor barrier in a context-dependent manner. Moreover, accumulating evidence has demonstrated that IR interacts profoundly with tumor-infiltrating immune cells, which cooperatively drive treatment outcomes...
2017: Frontiers in Immunology
https://www.readbyqxmd.com/read/28602947/radiation-exposure-from-depleted-uranium-the-radiation-bystander-effect
#17
Alexandra C Miller, Rafael Rivas, Leonard Tesoro, Gregor Kovalenko, Nikola Kovaric, Peter Pavlovic, David Brenner
Depleted uranium (DU) is a radioactive heavy metal used primarily in military applications. Published data from our laboratory have demonstrated that DU exposure in vitro to immortalized human osteoblast cells (HOS) is both neoplastically transforming and genotoxic. In vivo studies have also demonstrated that DU is leukemogenic and genotoxic. DU possesses both a radiological (alpha particle) and chemical (metal) component but is generally considered a chemical biohazard. Studies have shown that alpha particle radiation does play a role in DU's toxic effects...
June 8, 2017: Toxicology and Applied Pharmacology
https://www.readbyqxmd.com/read/28596291/ddx54-regulates-transcriptome-dynamics-during-dna-damage-response
#18
Miha Milek, Koshi Imami, Neelanjan Mukherjee, Francesca De Bortoli, Ulrike Zinnall, Orsalia Hazapis, Christian Trahan, Marlene Oeffinger, Florian Heyd, Uwe Ohler, Matthias Selbach, Markus Landthaler
The cellular response to genotoxic stress is mediated by a well-characterized network of DNA surveillance pathways. The contribution of posttranscriptional gene regulatory networks to the DNA damage response (DDR) has not been extensively studied. Here, we systematically identified RNA-binding proteins differentially interacting with polyadenylated transcripts upon exposure of human breast carcinoma cells to ionizing radiation (IR). Interestingly, more than 260 proteins including many nucleolar proteins showed increased binding to poly(A) RNA in IR-exposed cells...
June 8, 2017: Genome Research
https://www.readbyqxmd.com/read/28592116/radionuclides-in-radiation-induced-bystander-effect-may-it-share-in-radionuclide-therapy
#19
M Widel
For many years in radiobiology and radiotherapy predominated the conviction that cellular DNA is the main target for ionizing radiation, however, the view has changed in the past 20 years. Nowadays, it is assumed that not only directed (targeted) radiation effect, but also an indirect (non-targeted) effect may contribute to the result of radiation treatment. Non-targeted effect is relatively well recognized after external beam irradiation in vitro and in vivo, and comprises such phenomena like radiation-induced bystander effect (RIBE), genomic instability, adaptive response and abscopal (out of field) effect...
June 8, 2017: Neoplasma
https://www.readbyqxmd.com/read/28591589/can-%C3%AE-radiation-modulate-hemagglutinating-and-anticoagulant-activities-of-ppyll-a-lectin-from-phthirusa-pyrifolia
#20
Romero M P B Costa, Wendell Wagner Campos Albuquerque, Mariana C C Silva, Raiana Apolinário de Paula, Mychely Sheila Melo, Maria L V Oliva, Ana Lúcia Figueiredo Porto
Blood coagulation and platelet-dependent primary homeostasis are important defense mechanisms against bleeding and novel inhibitors have been researched to obtain pharmacological and clinical applications. In this work, the PpyLL, a lectin obtained from Phthirusa pyrifolia, was characterized in terms of its molecular structure and biological functions (anticoagulant, antiplatelet agreggation and hemagglutinating activities) in presence or absence of Gamma radiation exposure. Results revealed a lectin with secondary-structure content by approximately 49% of β-sheet, 20% of β-turn and 31% of disordered structure...
June 4, 2017: International Journal of Biological Macromolecules
keyword
keyword
104806
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"