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JOURNAL ARTICLE
Clara Podmore, Kevin Selby, Christopher D Jensen, Wei K Zhao, Noel S Weiss, Theodore R Levin, Joanne Schottinger, Chyke A Doubeni, Douglas A Corley
IMPORTANCE: Organized screening outreach can reduce differences in colorectal cancer (CRC) incidence and mortality between demographic subgroups. Outcomes associated with additional outreach, beyond universal outreach, are not well known. OBJECTIVE: To compare CRC screening completion by race and ethnicity, age, and sex after universal automated outreach and additional personalized outreach. DESIGN, SETTING, AND PARTICIPANTS: This observational cohort study included screening-eligible individuals aged 50 to 75 years assessed during 2019 in a community-based organized CRC screening program within the Kaiser Permanente Northern California (KPNC) integrated health care delivery setting...
April 1, 2024: JAMA Network Open
#2
JOURNAL ARTICLE
Aasma Shaukat, Theodore R Levin, Timothy R Church
No abstract text is available yet for this article.
April 2024: Annals of Internal Medicine
#3
JOURNAL ARTICLE
Jeffrey K Lee, Abhik Roy, Christopher D Jensen, Jennifer T Chan, Wei K Zhao, Theodore R Levin, Jessica Chubak, Ethan A Halm, Celette S Skinner, Joanne E Schottinger, Nirupa R Ghai, Andrea N Burnett-Hartman, Aruna Kamineni, Natalia Udaltsova, Douglas A Corley
IMPORTANCE: Postpolypectomy surveillance is a common colonoscopy indication in older adults; however, guidelines provide little direction on when to stop surveillance in this population. OBJECTIVE: To estimate surveillance colonoscopy yields in older adults. DESIGN, SETTING, AND PARTICIPANTS: This population-based cross-sectional study included individuals 70 to 85 years of age who received surveillance colonoscopy at a large, community-based US health care system between January 1, 2017, and December 31, 2019; had an adenoma detected 12 or more months previously; and had at least 1 year of health plan enrollment before surveillance...
April 1, 2024: JAMA Network Open
#4
JOURNAL ARTICLE
Harish Dharmarajan, Garret Choby, Ralph Abi Hachem, Edward C Kuan, Corinna G Levine, Olabisi Sanusi, Theodore Schuman, Dennis Tang, Michael Yim, Mathew Geltzeiler
Historically, comprehensive surgical resection for olfactory neuroblastoma has included the bilateral olfactory epithelium, cribriform plate, overlying dura, olfactory bulbs and tracts. This results in postoperative anosmia that may significantly impact a patient's quality of life without definitive added benefit in survival. The prevalence of occult intracranial disease is low, especially for Hyams grade I and II tumors. A unilateral approach sparing the contralateral cribriform plate and olfactory system can be considered for select cases of early stage, low-grade tumors when the disease does not cross midline to involve the contralateral olfactory cleft or septal mucosa and when midline dural margins can be cleared with frozen pathology...
March 25, 2024: International Forum of Allergy & Rhinology
#5
RANDOMIZED CONTROLLED TRIAL
Adam W Levin, Rafaelle Lancelotta, Nathan D Sepeda, Natalie Gukasyan, Sandeep Nayak, Theodore L Wagener, Frederick S Barrett, Roland R Griffiths, Alan K Davis
We examined if the therapeutic alliance between study participants and intervention facilitators in a psilocybin-assisted therapy (PAT) trial changed over time and whether there were relationships between alliance, acute psilocybin experiences, and depression outcomes. In a randomized, waiting list-controlled clinical trial for major depressive disorder in adults (N = 24), participants were randomized to an immediate (N = 13) or delayed (N = 11) condition with two oral doses of psilocybin (20mg/70kg and 30mg/70kg)...
2024: PloS One
#6
REVIEW
A Daniel Davidar, Kelly Jiang, Carly Weber-Levine, Meghana Bhimreddy, Nicholas Theodore
Applications and workflows around spinal robotics have evolved since these systems were first introduced in 2004. Initially approved for lumbar pedicle screw placement, the scope of robotics has expanded to instrumentation across different regions. Additionally, precise navigation can aid in tumor resection or spinal lesion ablation. Robot-assisted surgery can improve accuracy while decreasing radiation exposure, length of hospital stay, complication, and revision rates. Disadvantages include increased operative time, dependence on preoperative imaging among others...
April 2024: Neurosurgery Clinics of North America
#7
REVIEW
Andrew M Hersh, Carly Weber-Levine, Kelly Jiang, Nicholas Theodore
The mainstay of treatment for spinal cord injury includes decompressive laminectomy and elevation of mean arterial pressure. However, outcomes often remain poor. Extensive research and ongoing clinical trials seek to design new treatment options for spinal cord injury, including stem cell therapy, scaffolds, brain-spine interfaces, exoskeletons, epidural electrical stimulation, ultrasound, and cerebrospinal fluid drainage. Some of these treatments are targeted at the initial acute window of injury, during which secondary damage occurs; others are designed to help patients living with chronic injuries...
April 2024: Neurosurgery Clinics of North America
#8
JOURNAL ARTICLE
Jeffrey K Lee, Christopher D Jensen, Natalia Udaltsova, Yingye Zheng, Theodore R Levin, Jessica Chubak, Aruna Kamineni, Ethan A Halm, Celette S Skinner, Joanne E Schottinger, Nirupa R Ghai, Andrea Burnett-Hartman, Rachel Issaka, Douglas A Corley
OBJECTIVE: Colonoscopy surveillance guidelines categorize individuals as high or low risk for future colorectal cancer (CRC) based primarily on their prior polyp characteristics, but the approach is imprecise, and consideration of other risk factors may improve post-polypectomy risk stratification. METHODS: Among patients who underwent a baseline colonoscopy with removal of a conventional adenoma in 2004-2016, we compared the performance for post-polypectomy CRC risk prediction (through 2020) of a comprehensive model featuring patient age, diabetes diagnosis, and baseline colonoscopy indication and prior polyp findings (i...
February 14, 2024: American Journal of Gastroenterology
#9
JOURNAL ARTICLE
Kelly Jiang, Carly Weber-Levine, Nicholas Theodore
No abstract text is available yet for this article.
February 6, 2024: Operative Neurosurgery (Hagerstown, Md.)
#10
JOURNAL ARTICLE
Jeffrey K Lee, Pradeep C Koripella, Christopher D Jensen, Sophie A Merchant, Jeffrey M Fox, Suyi X Chang, Christian H Dang, Fernando S Velayos, Eshandeep S Boparai, Nicole S Evans, Lawrence J Leung, Jessica M Badalov, Charles P Quesenberry, Douglas A Corley, Theodore R Levin
BACKGROUND AND AIMS: Guidelines now recommend patients with low-risk adenomas receive colonoscopy surveillance in 7-10 years and those with the previously recommended 5-year interval be reevaluated. We tested three outreach approaches for transitioning patients to the 10-year interval recommendation. METHODS: Design: 3-arm pragmatic randomized trial comparing telephone, secure messaging, and mailed letter outreach. SETTING: Kaiser Permanente Northern California, a large integrated healthcare system...
January 6, 2024: Clinical Gastroenterology and Hepatology
#11
REVIEW
Vikas N Vattipally, Kelly Jiang, Carly Weber-Levine, Richard Rosin, A Daniel Davidar, Andrew M Hersh, Jawad Khalifeh, A Karim Ahmed, Tej D Azad, Kimberly Ashayeri, Daniel Lubelski, Debraj Mukherjee, Judy Huang, Nicholas Theodore
BACKGROUND: Exoscopes were recently developed as an alternative to the operative microscope (OM) and endoscope for intraoperative visualization in neurosurgery. Prior reviews studying mixed cranial and spinal surgical cohorts reported advantages of exoscope use, including improved ergonomics and teaching. In recent years, there has been an increase in exoscope research, with no updated systematic review focused exclusively on the benefits and limitations of exoscopes in spine surgery...
December 26, 2023: World Neurosurgery
#12
JOURNAL ARTICLE
Andrew M Hersh, Yike Jin, Risheng Xu, A Daniel Davidar, Carly Weber-Levine, L Fernando Gonzalez, Nicholas Theodore
BACKGROUND: Hemangiomas are common benign vascular lesions that rarely present with pain and neurological deficits. Symptomatic lesions are often treated with endovascular embolization. However, transarterial embolization can be technically challenging depending on the size and caliber of the vessels. Moreover, embolization can result in osteonecrosis and vertebral collapse. OBSERVATIONS: Here the authors report the first case of a T10 vertebral hemangioma treated with transpedicular Onyx embolization aided by a robotic platform that guided pedicle cannulation and Craig needle placement...
June 26, 2023: J Neurosurg Case Lessons
#13
JOURNAL ARTICLE
Tolulope Awosika, A Daniel Davidar, Andrew M Hersh, Arjun Menta, Carly Weber-Levine, Safwan Alomari, Majid Aziz Khan, Nicholas Theodore
OBJECTIVE: The differential diagnosis for postoperative back pain is broad, and conventional imaging modalities are not always conclusive. Therefore, we performed a systematic review of the literature and present case studies describing the use of single-photon emission CT (SPECT)/CT or positron emission tomography (PET)/CT in the diagnosis of back pain following spine surgery. METHODS: A systematic review was conducted according to PRISMA guidelines across 5 databases...
November 25, 2023: World Neurosurgery
#14
JOURNAL ARTICLE
Po-Hong Liu, Rasmi G Nair, Celette Sugg Skinner, Caitlin C Murphy, Eric J Kim, Cynthia Ortiz, Lei Wang, Ellen Hu, Jacquelyn M Lykken, Theodore R Levin, Beverly B Green, Erin E Hahn, Noel Santini, Ethan A Halm
BACKGROUND: Fecal immunochemical test (FIT) is an effective colorectal cancer screening modality. Little is known about prevalence, reasons, and testing after unsatisfactory FIT, or a FIT that cannot be processed by the laboratory due to inadequate stool specimen or incomplete labeling. METHODS: Our retrospective cohort study examined unsatisfactory FIT among average-risk individuals aged 50-74 years in a large, integrated, safety-net health system who completed an index FIT from 2010 to 2019...
November 15, 2023: Cancer Epidemiology, Biomarkers & Prevention
#15
REVIEW
Shahab Aldin Sattari, Albert Antar, John N Theodore, Andrew M Hersh, Abdel-Hameed Al-Mistarehi, A Daniel Davidar, Carly Weber-Levine, Tej D Azad, Wuyang Yang, James Feghali, Risheng Xu, Amir Manbachi, Daniel Lubelski, Chetan Bettegowda, Louis Chang, Timothy Witham, Allan Belzberg, Nicholas Theodore
BACKGROUND CONTEXT: The optimal decompression time for patients presenting with acute traumatic central cord syndrome (ATCCS) has been debated, and a high level of evidence is lacking. PURPOSE: To compare early (<24 hours) versus late (≥24 hours) surgical decompression for ATCCS. STUDY DESIGN: Systematic review and meta-analysis. METHODS: Medline, PubMed, Embase, and CENTRAL were searched from inception to March 15th, 2023...
October 25, 2023: Spine Journal: Official Journal of the North American Spine Society
#16
JOURNAL ARTICLE
Ingmar F Rompen, Jonah Levine, Joseph R Habib, Elisabetta Sereni, Nabiha Mughal, D Brock Hewitt, Greg D Sacks, Theodore H Welling, Diane M Simeone, Brian Kaplan, Russell S Berman, Steven M Cohen, Christopher L Wolfgang, Ammar A Javed
OBJECTIVE: This study aimed to analyze post-recurrence progression in context of recurrence sites and assess implications for post-recurrence treatment. BACKGROUND: Most patients with resected pancreatic ductal adenocarcinoma (PDAC) recur within two years. Different survival outcomes for location-specific patterns of recurrence are reported, highlighting their prognostic value. However, a lack of understanding of post-recurrence progression and survival remains...
October 23, 2023: Annals of Surgery
#17
REVIEW
Edward C Kuan, Eric W Wang, Nithin D Adappa, Daniel M Beswick, Nyall R London, Shirley Y Su, Marilene B Wang, Waleed M Abuzeid, Borislav Alexiev, Jeremiah A Alt, Paolo Antognoni, Michelle Alonso-Basanta, Pete S Batra, Mihir Bhayani, Diana Bell, Manuel Bernal-Sprekelsen, Christian S Betz, Jean-Yves Blay, Benjamin S Bleier, Juliana Bonilla-Velez, Claudio Callejas, Ricardo L Carrau, Roy R Casiano, Paolo Castelnuovo, Rakesh K Chandra, Vasileios Chatzinakis, Simon B Chen, Alexander G Chiu, Garret Choby, Naweed I Chowdhury, Martin J Citardi, Marc A Cohen, Roi Dagan, Gianluca Dalfino, Iacopo Dallan, Camila Soares Dassi, John de Almeida, Angelo P Dei Tos, John M DelGaudio, Charles S Ebert, Ivan H El-Sayed, Jean Anderson Eloy, James J Evans, Christina H Fang, Nyssa F Farrell, Marco Ferrari, Nancy Fischbein, Adam Folbe, Wytske J Fokkens, Meha G Fox, Valerie J Lund, Gary L Gallia, Paul A Gardner, Mathew Geltzeiler, Christos Georgalas, Anne E Getz, Satish Govindaraj, Stacey T Gray, Jessica W Grayson, Bradley A Gross, Jordon G Grube, Ruifeng Guo, Patrick K Ha, Ashleigh A Halderman, Ehab Y Hanna, Richard J Harvey, Stephen C Hernandez, Adam L Holtzman, Claire Hopkins, Zhigang Huang, Zhenxiao Huang, Ian M Humphreys, Peter H Hwang, Alfred M Iloreta, Masaru Ishii, Michael E Ivan, Aria Jafari, David W Kennedy, Mohemmed Khan, Adam J Kimple, Todd T Kingdom, Anna Knisely, Ying-Ju Kuo, Devyani Lal, Eric D Lamarre, Ming-Ying Lan, Hien Le, Matt Lechner, Nancy Y Lee, Jivianne K Lee, Victor H Lee, Corinna G Levine, Jin-Ching Lin, Derrick T Lin, Brian C Lobo, Tran Locke, Amber U Luong, Kelly R Magliocca, Svetomir N Markovic, Gesa Matnjani, Erin L McKean, Cem Meço, William M Mendenhall, Loren Michel, Shorook Na'ara, Piero Nicolai, Daniel W Nuss, Gurston G Nyquist, Gretchen M Oakley, Kazuhiro Omura, Richard R Orlandi, Nobuyoshi Otori, Peter Papagiannopoulos, Zara M Patel, David G Pfister, Jack Phan, Alkis J Psaltis, Mindy R Rabinowitz, Murugappan Ramanathan, Ryan Rimmer, Marc R Rosen, Olabisi Sanusi, Zoukaa B Sargi, Philippe Schafhausen, Rodney J Schlosser, Ahmad R Sedaghat, Brent A Senior, Raj Shrivastava, Raj Sindwani, Timothy L Smith, Kristine A Smith, Carl H Snyderman, C Arturo Solares, Satyan B Sreenath, Aldo Stamm, Katharina Stölzel, Baran Sumer, Pavol Surda, Bobby A Tajudeen, Lester D R Thompson, Brian D Thorp, Charles C L Tong, Raymond K Tsang, Justin H Turner, Mario Turri-Zanoni, Aaron M Udager, Thibaut van Zele, Kyle VanKoevering, Kevin C Welch, Sarah K Wise, Ian J Witterick, Tae-Bin Won, Stephanie N Wong, Bradford A Woodworth, Peter-John Wormald, William C Yao, Chien-Fu Yeh, Bing Zhou, James N Palmer
BACKGROUND: Sinonasal neoplasms, whether benign and malignant, pose a significant challenge to clinicians and represent a model area for multidisciplinary collaboration in order to optimize patient care. The International Consensus Statement on Allergy and Rhinology: Sinonasal Tumors (ICSNT) aims to summarize the best available evidence and presents 48 thematic and histopathology-based topics spanning the field. METHODS: In accordance with prior International Consensus Statement on Allergy and Rhinology documents, ICSNT assigned each topic as an Evidence-Based Review with Recommendations, Evidence-Based Review, and Literature Review based on the level of evidence...
February 2024: International Forum of Allergy & Rhinology
#18
Karl Kwok, Theodore R Levin, Jason A Dominitz, Kashyap Panganamamula, Andrew D Feld, Bruce Bardall, Kara Newbury, Lukejohn W Day
No abstract text is available yet for this article.
August 23, 2023: Gastrointestinal Endoscopy
#19
JOURNAL ARTICLE
Margaret P Schmill, Zoe Thompson, Daisy Lee, Laurence Haddadin, Shaarang Mitra, Raymond Ezzat, Samantha Shelton, Phillip Levin, Sogol Behnam, Kelly J Huffman, Theodore Garland
Uncovering relationships between neuroanatomy, behavior, and evolution is important for understanding the factors that control brain function. Voluntary exercise is one key behavior that both affects, and may be affected by, neuroanatomical variation. Moreover, recent studies suggest an important role for physical activity in brain evolution. We used a unique and ongoing artificial selection model in which mice are bred for high voluntary wheel-running behavior, yielding four replicate lines of High Runner (HR) mice that run ~3-fold more revolutions per day than four replicate non-selected Control (C) lines...
August 21, 2023: Brain, Behavior and Evolution
#20
JOURNAL ARTICLE
Kelly Jiang, Andrew M Hersh, Meghana Bhimreddy, Carly Weber-Levine, A Daniel Davidar, Arjun K Menta, Denis Routkevitch, Safwan Alomari, Brendan F Judy, Daniel Lubelski, Jon Weingart, Nicholas Theodore
BACKGROUND AND OBJECTIVES: Robot-assisted pedicle screw placement is associated with greater accuracy, reduced radiation, less blood loss, shorter hospital stays, and fewer complications than freehand screw placement. However, it can be associated with longer operative times and an extended training period. We report the initial experience of a surgeon using a robot system at an academic medical center. METHODS: We retrospectively reviewed all patients undergoing robot-assisted pedicle screw placement at a single tertiary care institution by 1 surgeon from 10/2017 to 05/2022...
August 14, 2023: Operative Neurosurgery (Hagerstown, Md.)
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