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Reducing caesarian section rate

Zhen-Yu Luo, Song Quan, Dong-Ning Chai, Wei-Hong Zhang
The retrospective cohort epidemiological study was to investigate the characteristics of women who underwent induced abortion. Data were retrospectively collected from women who underwent induced abortions (n = 19,655) at the Xiamen Maternity and Child Health Care Hospital (2010-2013). The characteristics of women who underwent induced abortions included mean age, unmarried status, no previous deliveries, first pregnancy, ≥2 abortions including the current one, and a history of caesarian section. From 2010 to 2013, mean age increased and declines were observed in the ratio of induced abortions to live births, the proportion of induced abortions among women of 15-24 years, those who were unmarried, had their first pregnancy, or had no history of delivery...
2016: BioMed Research International
J Robert Smith, Kyle Pfeifer, Florian Petry, Natalie Powell, Jennifer Delzeit, Mark L Weiss
Umbilical cord derived mesenchymal stromal cells (UC-MSCs) are a focus for clinical translation but standardized methods for isolation and expansion are lacking. Previously we published isolation and expansion methods for UC-MSCs which presented challenges when considering good manufacturing practices (GMP) for clinical translation. Here, a new and more standardized method for isolation and expansion of UC-MSCs is described. The new method eliminates dissection of blood vessels and uses a closed-vessel dissociation following enzymatic digestion which reduces contamination risk and manipulation time...
2016: Stem Cells International
A Rahmani, B Afandi
BACKGROUND: Gestational Diabetes Mellitus (GDM) is a common condition that affects pregnant women and may result in maternal as well as fetal and neonatal complications. Optimal coordinated management may reduce these complications if applied in team approach following generally accepted international guidelines. METHODS: A retrospective analysis of the neonatal outcomes of GDM mothers who were followed in a tertiary medical center in the United Arab Emirates. The aim of the study was to assess the efficacy of a comprehensive and multidisciplinary GDM program which was applied to a quality improvement project...
2015: Journal of Neonatal-perinatal Medicine
Ghasem Soltani, Amirmasoud Molkizadeh, Shahram Amini
BACKGROUND: Use of analgesics, especially opioids, before delivery during cesarean section for preventing hemodynamic changes after endotracheal intubation and postoperative analgesia is limited due to their adverse effects on the neonate. OBJECTIVES: The aim of this study was to investigate the effect of intravenous acetaminophen (paracetamol) in blunting hemodynamic responses to endotracheal intubation and postoperative pain in parturient undergoing cesarean section by general anesthesia...
December 2015: Anesthesiology and Pain Medicine
Sadic Kagwa, Mark A Hoeft, Paul G Firth, Stephen Ttendo, Vicki E Modest
BACKGROUND: Transversus abdominis plane (TAP) block provides 12-24 h of analgesia to the parietal peritoneum and abdominal wall, and are best used combined with oral or intravenous medications. Despite ease of use, a large margin of safety, and a high success rate, TAP blocks remain under used in settings where patients could most benefit from their use. Previous studies have used oral or intravenous narcotics for supplementation. However, the efficacy of TAP blocks in low-resourced settings where patients do not have dependable access to these medications is unknown...
April 27, 2015: Lancet
C Santoro, R Di Mauro, E Baldacci, F De Angelis, R Abbruzzese, F Barone, R A Bochicchio, G Ferrara, A Guarini, R Foà, M G Mazzucconi
Bleeding phenotype in factor XI (FXI)-deficient patients is variable, and not related to baseline FXI:Act. Aims of our study were to describe the characteristics and the management of surgery and deliveries in FXI-deficient patients, and to investigate the relationship between the haemorrhagic phenotype and the baseline FXI:Act. Ninety-five patients were diagnosed and followed in our centre for a median follow-up of 0.9 years (0.1-36.2); median FXI:Act of all patients: 38% (0.5-69%). Fifty-six patients (59%) experienced bleeding episodes not surgery-related...
July 2015: Haemophilia: the Official Journal of the World Federation of Hemophilia
John J McCarthy, Martin H Leamon, Neil H Willits, Ruth Salo
OBJECTIVES: To evaluate the effects of a multiple daily dose methadone regimen in pregnancy on neonatal outcomes. METHODS: Although methadone maintenance has been the standard for the treatment of opioid dependence in pregnancy, there is no consensus on proper dosing. Single daily dosing is the most common strategy. Because of accelerated metabolism of methadone in pregnancy, this regimen may expose mother and fetus to daily episodes of withdrawal and possibly contribute to more severe Neonatal Abstinence Syndrome (NAS)...
March 2015: Journal of Addiction Medicine
Ali Abood, Peter Vestergaard
OBJECTIVE: To study pregnancy and pregnancy outcomes in women with primary hyperparathyroidism (PHPT) and in controls. DESIGN: Register-based retrospective cohort study of women aged 16-44 years with a diagnosis of PHPT with age- and gender-matched non-exposed controls in Denmark. METHODS: The patients and controls were identified using the Danish National Hospital Discharge Register for the period 1977-2010. The outcomes were determined using the Birth Register, the Abortion Register and the LPR (National Hospital Discharge Register)...
July 2014: European Journal of Endocrinology
Innocent O George, Israel Jeremiah
BACKGROUND: Eclampsia is a leading cause of maternal and perinatal mortality in Nigeria. Preventive and interventional measures have been shown to reduce maternal mortality and morbidity with no significant beneficial effect on neonatal outcomes. The aim of this study is to assess the perinatal outcome of eclampsia at the University of Port-Harcourt Teaching Hospital (UPTH). MATERIALS AND METHODS: This prospective, cross-sectional study was conducted on 88 consecutive patients presenting with antepartum eclampsia at the UPTH between 1(st) January 2007 and 31(st) December 2008...
December 2009: International Journal of Biomedical Science: IJBS
Ejub Basic, Vesna Basic-Cetkovic, Hadzo Kozaric, Admir Rama
INTRODUCTION: The rate of attempted vaginal birth after previous cesarean delivery has decreased, while the success rate of such births increased. Advances in surgical techniques, the development of anesthesiology services, particularly endotracheal anesthesia, very quality postoperative care with cardiovascular, respiratory and biochemical resuscitation, significantly reduce maternal mortality and morbidity after cesarean section. Progress and development of neonatal services, and intensive care of newborns is enabled and a high survival of newborn infants...
September 2012: Acta Informatica Medica: AIM
Dorra Zeghal, Amira Ayachi, Sami Mahjoub, Ghassen Boulahya, Aymen Zakraoui, Rim Ben Hmid, Faouzia Zouari
AIM: To study the maternal and fetal morbidity in the association fibroid and pregnancy and the management in this case. METHODS: A retrospective study of 80 cases of fibroids associated to pregnancy. These cases were taken from the department "C" of gynecology and obstetrics in the center of maternity and neonatology of Tunis. RESULTS: We studied 80 cases of fibroid associated to pregnancy in our study. The mean age of the patients was 32 years old...
April 2012: La Tunisie Médicale
Siva Subramanian, Kathy S Katz, Margaret Rodan, Marie G Gantz, Nabil M El-Khorazaty, Allan Johnson, Jill Joseph
While biomedical risks contribute to poor pregnancy and neonatal outcomes in African American (AA) populations, behavioral and psychosocial risks (BPSR) may also play a part. Among low income AA women with psychosocial risks, this report addresses the impacts on pregnancy and neonatal outcomes of an integrated education and counseling intervention to reduce BPSR, as well as the contributions of other psychosocial and biomedical risks. Subjects were low income AA women ≥18 years living in the Washington, DC, metropolitan area and seeking prenatal care...
April 2012: Maternal and Child Health Journal
Patrycja J Puiman, Mikkel Jensen, Barbara Stoll, Ingrid B Renes, Adrianus C J M de Bruijn, Kristien Dorst, Henk Schierbeek, Mette Schmidt, Günther Boehm, Douglas G Burrin, Per T Sangild, Johannes B van Goudoever
Threonine is an essential amino acid necessary for synthesis of intestinal (glyco)proteins such as mucin MUC2 to maintain adequate gut barrier function. In premature infants, reduced barrier function may contribute to the development of necrotizing enterocolitis (NEC). Human milk protects against NEC compared with infant formula. Therefore, we hypothesized that formula feeding decreases the MUC2 synthesis rate concomitant with a decrease in intestinal first-pass threonine utilization, predisposing the preterm neonate to NEC...
July 2011: Journal of Nutrition
Peace I Opara, Tamunopriye Jaja, Uche C Onubogu
BACKGROUND: Infants born to diabetic women have certain distinctive characteristics, including large size and high morbidity risks. The neonatal mortality rate is over five times that of infants of non diabetic mothers and is higher at all gestational ages and birth weight for gestational age (GA) categories.The study aimed to determine morbidity and mortality pattern amongst infants of diabetic mothers (IDMS) admitted into the Special Care Baby Unit of University of Port Harcourt Teaching Hospital...
2010: Italian Journal of Pediatrics
C Bohec, M Collet
Retroplacental haematoma (RPH) is a complication affecting 0.25 to 0.4% of all pregnancies and 4% of severe PEs. It is of acute onset, usually unpredictable and its symptoms are not specific: Isolated metrorrhagia, foetal distress, uterine hypertonicity. Clinical, biological and sonographic features suggesting a RPH can be early or late. Haemoconcentration and the forming of notches on Doppler examination of the uterus can appear weeks before the event, whereas raised D-Dimers and foetal tachycardia are identified within days of the event...
May 2010: Annales Françaises D'anesthèsie et de Rèanimation
Badrunnesa Begum, Rashid Uz Zaman, Ashequr Rahman, M Saifur Rahaman, M Kamal Uddin, Rumana Hafiz, Fahmida Abedin
A comparative study was done to compare risks and benefits of normal vaginal and caesarean section delivery. One hundred women between 36 to 40 weeks gestation were enrolled and face to face interviews and clinical assessments were conducted both in antenatal and postnatal period. Though 98% preferred vaginal birth only 45% eventually had so. Both immediate and late complications were considerably more in caesarian section than in normal vaginal delivery. Mean duration of sickness and mean days required for returning to normal activities were also higher in case of caesarian section...
January 2009: Mymensingh Medical Journal: MMJ
M K Jahan, M Shafiquzzaman, K Nahar, M Rahman, N Sultana, M M Rahman, R Begum
Pregnancy outcome among women in the age group of 35 years and more are considered to be less favorable than those of younger women. To observe those, this case control study was conducted in the department of Obstetrics & Gynaecology, Mymensingh Medical College Hospital during the period of 1st June 2003 to 31st May 2004. The study includes 100 patients of 35 years of age or above and 100 controls of 20-30 years of age. Observed complications during the pregnancy and delivery were increased incidence of placenta previa, malpresentation, intrauterine death, preterm labour, obstructed labour ruptured uterus etc...
January 2009: Mymensingh Medical Journal: MMJ
S R Brown, P B Goodfellow
BACKGROUND: The choice of surgical incision in the abdomen is determined by access for surgery. It has been suggested that utilising a transverse or oblique rather than a midline incision may influence other parameters such as recovery and complication rates. However, there is little consensus in the literature as to whether a particular incision confers any advantage. OBJECTIVES: To determine whether a midline incision or a transverse incision (including oblique incision) confers any recovery advantage to the patient...
2005: Cochrane Database of Systematic Reviews
Hanne G Pedersen, Mette Schmidt, Per T Sangild, Lotte Strøbech, Gábor Vajta, Henrik Callesen, Torben Greve
Nuclear transfer in cattle has been shown to cause a high frequency of conceptus loss, excessive accumulation of allantoic fluid, increased birth weight as well as peri- and neonatal deaths. The aims of this preliminary study were to investigate the in vivo development of embryos and fetuses produced by a novel somatic cell cloning method, denominated handmade cloning (HMC), and to characterize the premature calves delivered by Caesarian section. Twenty-five day 7 fresh embryos including seven blastocysts produced by aggregation of two day 4 embryos, and seven vitrified embryos were transferred to synchronized Holstein-Friesian heifers...
April 29, 2005: Molecular and Cellular Endocrinology
Kentaro Setoyama, Takeshi Shinzato, Kazuhiro Misumi, Makoto Fujiki, Hiroshi Sakamoto
To determine the effects of propofol and sevoflurane on hemodynamics, acid-base balance and uterine activity in pregnant animals, a prospective experimental study was designed by use of ten pregnant goats. Propofol was intravenously administered at a bolus dose of 5 mg/kg and then infused a rate of 0.3 mg/kg/min for 5 min. Following the induction, the animals were incrementally inhaled 2.7 and 4.1% of end-tidal concentration of sevoflurane each for 30 min, and then recovered. The maternal and fetal heart rate (HR), arterial blood pressure (BP) and acid-base balance, the intrauterine pressure (IUP), and the uterine blood flow (UBF) were measured...
October 2003: Journal of Veterinary Medical Science
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