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Genital tuberculosis

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https://www.readbyqxmd.com/read/27921005/primary-tuberculosis-of-cervix-a-coincidental-finding
#1
Nalini Sharma, Ahanthem Santa Singh, Yookarin Khonglah, Jaya Mishra
BACKGROUND: 95% of Tuberculosis (TB) of the female genital tract (FGT) is located in tissues other than the cervix. A rare case of primary TB of the cervix which was diagnosed coincidently in a patient of endometrioma was reported in this study. CASE PRESENTATION: A 34 year old nullipara, a diagnosed case of endometrioma had a small cervical growth. Pap smear and biopsy was taken and sent for histopathological examination. Her histopathological examination revealed multiple epitheloid cell granuloma and langerhans type giant cell caeseation...
October 2016: Journal of Reproduction & Infertility
https://www.readbyqxmd.com/read/27875026/disseminated-bcg-pneumonitis-revealing-severe-combined-immunodeficiencyxs-in-charge-syndrome
#2
Hyung Young Kim, Yoo-Mi Kim, Hee Ju Park
CHARGE (coloboma, heart defect, atresia choanae, retarded growth and development, genital hypoplasia, and ear anomalies/deafness) syndrome is a rare genetic disorder caused by CHD7 mutation and is related to immunodeficiency. A 6-month-old girl with right lung agenesis, congenital heart defects, and ear anomalies developed repeated and serious respiratory infection for a short period. She was clinically diagnosed with typical CHARGE syndrome with severe combined immunodeficiency (T-, B+, NK-); however, CHD7 mutation was not detected...
November 22, 2016: Pediatric Pulmonology
https://www.readbyqxmd.com/read/27865222/endometrial-tuberculosis-simulating-an-ovarian-cancer-a-case-report
#3
Silvia Eleonora Di Giovanni, Teresa Margarida Cunha, Ana Luisa Duarte, Ines Alves
Female genital tuberculosis remains a major health problem in developing countries and is an important cause of infertility. As symptoms, laboratory data and physical findings are non-specific, its diagnosis can be difficult. We describe a case of a 39-year-old woman suffering from peri-umbilical pain and increased abdominal size for one year, anorexia, asthenia, weight loss, occasionally dysuria and dyspareunia, and four months amenorrhea. Laboratory data revealed cancer antigen 125 (CA-125) level of 132.3 U/mL, erythrocyte sedimentation rate of 42 mm/h, and gamma-globulins of 2...
June 2016: Acta Médica Portuguesa
https://www.readbyqxmd.com/read/27858862/utility-of-t-cell-interferon-%C3%AE-release-assays-for-the-diagnosis-of-female-genital-tuberculosis-in-a-tertiary-referral-hospital-in-beijing-china
#4
Xiaoqing Liu, Sainan Bian, Xinhe Cheng, Wenze Wang, Qinjie Tian, Lifan Zhang, Yueqiu Zhang, Xiaochun Shi, Yao Zhang, Zhiyong Liang
Diagnosis of female genital tuberculosis (FGTB) remains a challenge. The aim of this study was to evaluate the diagnostic value of T-SPOT.TB on peripheral blood mononuclear cells (PBMCs) for diagnosing FGTB in an area with high TB burden.Patients with suspected FGTB were enrolled consecutively between August 2010 and August 2015. T-SPOT.TB on PBMCs and histopathology were performed in all patients. T-SPOT.TB results were evaluated against patients' final diagnosis of FGTB which was made based on clinical manifestations, radiology, microbiological and histopathological evaluation, and response to anti-TB treatment...
November 2016: Medicine (Baltimore)
https://www.readbyqxmd.com/read/27847026/genital-tuberculosis-unusual-presentations
#5
Bindiya Gupta, Sneha Shree, Shalini Rajaram, Neerja Goel
Genital tract tuberculosis is usually secondary to extragenital tuberculosis. The upper genital tract is usually involved; involvement of cervix and vulva is very uncommon. We present two such rare cases of vulval and cervical tuberculosis diagnosed on histopathology and treated with antitubercular chemotherapy.
September 2016: International Journal of Mycobacteriology
https://www.readbyqxmd.com/read/27847017/laparoscopy-in-the-diagnosis-of-tuberculosis-in-chronic-pelvic-pain
#6
Shalini Rajaram, Priyanka Gupta, Bindiya Gupta, Iqbal R Kaur, Neerja Goel
BACKGROUND: To estimate the prevalence of genital tuberculosis in women with idiopathic chronic pelvic pain on laparoscopy, correlate laparoscopic findings with microbiological and histological diagnosis of tuberculosis and assess the response to anti tubercular treatment (ATT) in these cases. METHOD: In a prospective cohort study, fifty women with idiopathic chronic pelvic pain were enrolled. Diagnostic laparoscopy was done in all women and fluid from pouch of Douglas and/or saline washings were sent for acid fast bacilli (AFB) smear, conventional and rapid culture and DNA polymerase chain reaction (PCR) analysis for diagnosis of genital TB...
September 2016: International Journal of Mycobacteriology
https://www.readbyqxmd.com/read/27843865/a-rare-case-of-isolated-testicular-tuberculosis-and-review-of-literature
#7
Anirban Das, Saikat Batabyal, Soumya Bhattacharjee, Amitabha Sengupta
Testicular tuberculosis (TB) is a rare form of genitourinary TB. It is usually presented as painful or painless testicular swelling with or without scrotal ulceration or discharging sinus. Infertility may occur. Epididymal involvement is usually seen in testicular TB. In most cases, genital TB is associated with TB involvement of kidneys or lower urinary tract. Ultrasound (USG) and USG-guided fine needle aspiration cytology of testicular swelling confirm the diagnosis. Anti-TB chemotherapy is the mainstay of treatment to ensure the complete resolution of the lesion...
April 2016: Journal of Family Medicine and Primary Care
https://www.readbyqxmd.com/read/27803581/effect-of-antitubercular-treatment-on-ovarian-function-in-female-genital-tuberculosis-with-infertility
#8
Jai Bhagwan Sharma, J Sneha, U B Singh, Sunesh Kumar, K K Roy, Neeta Singh, Sona Dharmendra
AIM: To evaluate the effect of antitubercular therapy (ATT) on an ovarian function such as ovarian reserve, ovarian dimensions, and ovarian stromal blood flow. SETTINGS AND DESIGN: Prospective study design. MATERIALS AND METHODS: Fifty infertile women with female genital tuberculosis (FGTB) without tubo-ovarian masses diagnosed by positive acid-fast bacilli culture or epithelioid granuloma on endometrial aspirate or positive polymerase chain reaction with positive findings on laparoscopy or hysteroscopy were recruited...
July 2016: Journal of Human Reproductive Sciences
https://www.readbyqxmd.com/read/27803580/insight-into-the-diagnosis-and-management-of-subclinical-genital-tuberculosis-in-women-with-infertility
#9
REVIEW
Nalini Mahajan, Padmaja Naidu, Simran Deep Kaur
Genital tuberculosis (GTB) is an important cause of infertility in India. Lack of an accurate diagnostic test has led to an indiscriminate use of antitubercular treatment in infertile women. Apart from concerns of drug toxicity, this may be a contributing factor in the increasing incidence of multidrug-resistant TB reported in India. We conducted a study to analyze whether a combination of tests could help improve diagnostic accuracy. An algorithm for the management of GTB in infertile women based on the use of multiple tests is presented...
July 2016: Journal of Human Reproductive Sciences
https://www.readbyqxmd.com/read/27750273/a-case-report-of-severe-neuro-behcet-s-disease-treated-with-a-combination-of-immunosuppressives-and-a-tnf-inhibitor-a-difficult-therapeutic-choice
#10
Fatma Nur Korkmaz, Gulsen Ozen, Ali Uğur Ünal, Pınar Kahraman Koytak, Nese Tuncer, Haner Direskeneli
Abstract/ Resumo Behcet's disease (BD) is a multisystem inflammatory disorder characterized by recurrent oral and genital ulcers, skin lesions and uveitis. The nervous system involvement of BD, neuro-Behcet's disease (NBD), is one of the important causes of mortality of the disease. Herein, we present a 29-year-old male with parenchymal NBD who has progressed rapidly and was managed with an uncommon aggressive immunosuppresive combination therapy. The patient first presented six years ago with vertigo and difficulty in talking and walking...
September 28, 2016: Acta Reumatológica Portuguesa
https://www.readbyqxmd.com/read/27733282/global-regional-and-national-incidence-prevalence-and-years-lived-with-disability-for-310-diseases-and-injuries-1990-2015-a-systematic-analysis-for-the-global-burden-of-disease-study-2015
#11
COMMENT
(no author information available yet)
BACKGROUND: Non-fatal outcomes of disease and injury increasingly detract from the ability of the world's population to live in full health, a trend largely attributable to an epidemiological transition in many countries from causes affecting children, to non-communicable diseases (NCDs) more common in adults. For the Global Burden of Diseases, Injuries, and Risk Factors Study 2015 (GBD 2015), we estimated the incidence, prevalence, and years lived with disability for diseases and injuries at the global, regional, and national scale over the period of 1990 to 2015...
October 8, 2016: Lancet
https://www.readbyqxmd.com/read/27678765/genital-tuberculosis-in-female-infertility-an-enigma
#12
Luthra A M
No abstract text is available yet for this article.
November 2015: Journal of Minimally Invasive Gynecology
https://www.readbyqxmd.com/read/27668207/cervical-xanthogranuloma-in-a-case-of-postmenopausal-pyometra
#13
Alpana Singh, Garima Vats, A G Radhika, Pragati Meena, Gita Radhakrisnan
Xanthogranuloma is a non-neoplastic presentation of chronic inflammation commonly seen in gallbladder, kidney and rarely seen in genital organs. Only one case has been reported in cervix. Here, we report a case of 60-year-old postmenopausal lady who presented with history of fever and purulent discharge per-vaginum. On speculum examination, cervix had an ulcer extending from 3 to 5 o'clock position. Uterus was bulky. On probing the ulcer, a 1-cm deep sinus was identified. Ultrasound showed enlarged uterus and fluid collection suggestive of pyometra...
September 2016: Obstetrics & Gynecology Science
https://www.readbyqxmd.com/read/27642459/patients-with-secondary-amenorrhea-due-to-tuberculosis-endometritis-towards-the-induced-anti-tuberculosis-drug-category-1
#14
Raditya Perdhana, Sutrisno Sutrisno, Yani Jane Sugiri, Siti Candra Windu Baktiyani, Arsana Wiyasa
Tuberculosis (TB) is a disease which can affect various organs, including human's genital organs such as the endometrium. Tuberculosis endometritis can cause clinical symptoms of secondary amenorrhea and infertility. Infertility in genital TB caused by the involvement of the endometrium. The case presentation is 33-year-old woman from dr. Saiful Anwar Public Hospital to consult that she has not menstruated since 5 years ago (28 years old). The diagnosis was done by performing a clinical examination until the diagnosis of secondary amenorrhea due to tuberculosis endometritis is obtained...
2016: Pan African Medical Journal
https://www.readbyqxmd.com/read/27514954/loop-mediated-isothermal-amplification-assay-for-detection-of-mycobacterium-tuberculosis-complex-in-infertile-women
#15
S Sethi, L Dhaliwal, P Dey, H Kaur, R Yadav, S Sethi
BACKGROUND: Female genital tuberculosis (FGTB) has a profound impact on the reproductive health of patients including infertility. Conventional diagnostic techniques have low sensitivity and specificity as well as long turnaround time. There is a need of developing newer, rapid and practically adaptable technique, especially in low-income countries. OBJECTIVE: To standardize and evaluate loop-mediated isothermal amplification (LAMP) technique for diagnosis of FGTB...
July 2016: Indian Journal of Medical Microbiology
https://www.readbyqxmd.com/read/27476253/-genital-tuberculosis-atypical-manifestation-in-the-pregnancy-case-report
#16
A Franco-Sansaloni, J Vizcaíno-Torres, J Gaona-Morales, D Estellés-Morant, J Antonio-Serrano
BACKGROUND: In the last years has been an increase in cases of tu- berculosis, representing a global health problem that is also reflected in an increased of cases in pregnant population. Especially in developed countries has been observed a direct relation with VIH patients,and groups of immigrants from countries where the infection is endemic. Tuberculous disease during pregnancy presents good outcome if it is diagnosed and treated properly. CASE REPORT: We present the case of a romanian patient with uncon- trolled 23 weeks gestation that enters with the suspicion of chorioam- nionitis and after late septic miscarriage and clinical sepsis criteria, leaks out of the hospital reentering with signs of neurologic involvement and pelviperitonitis as a result of genital tuberculous...
May 2016: Ginecología y Obstetricia de México
https://www.readbyqxmd.com/read/27391900/six-months-versus-nine-months-anti-tuberculous-therapy-for-female-genital-tuberculosis-a-randomized-controlled-trial
#17
Jai B Sharma, Neeta Singh, Sona Dharmendra, Urvashi B Singh, Vanamail P, Sunesh Kumar, K K Roy, Smriti Hari, V Iyer, S K Sharma
OBJECTIVE: To compare six months versus nine months anti-tuberculous therapy in patients of female genital tuberculosis. STUDY DESIGN: It was a randomized controlled trial in a tertiary referral center teaching institute on 175 women presenting with infertility and found to have female genital tuberculosis on clinical examination and investigations. Group I women (86 women) were given 9 months of intermitted anti-tuberculous therapy under directly observed treatment short course (DOTS) strategy while Group II (89 women) were given 6 months of anti-tuberculous therapy under DOTS...
August 2016: European Journal of Obstetrics, Gynecology, and Reproductive Biology
https://www.readbyqxmd.com/read/27365923/sharma-s-python-sign-a-new-tubal-sign-in-female-genital-tuberculosis
#18
Jai Bhagwan Sharma
Female genital tuberculosis (FGTB) is an important cause of infertility in developing countries. Various type of TB salpingitis can be endosalpingitis, exosalpingitis, interstitial TB salpingitis, and salpingitis isthmica nodosa. The fallopian tubes are thickened enlarged and tortuous. Unilateral or bilateral hydrosalpinx or pyosalpinx may be formed. A new sign python sign is presented in which fallopian tube looks like a blue python on dye testing in FGTB.
July 2016: Journal of Laboratory Physicians
https://www.readbyqxmd.com/read/27362427/refugees-of-the-syrian-civil-war-impact-on-reemerging-infections-health-services-and-biosecurity-in-turkey
#19
Mehmet Doganay, Hayati Demiraslan
After the Arab Spring uprising, Syria descended into a civil war in 2011. By March 2016, the United Nations reported that 13.5 million Syrians required humanitarian assistance, including 6.6 million internally displaced persons and more than 4.8 million refugees outside of Syria. Turkey is currently hosting the largest number of Syrian refugees-more than 2.7 million. A limited number of refugees are living in camps settled around the border, and others are spread throughout Turkey. This explosive and unexpected increase in the Syrian population in Turkey has had several negative impacts on health and social determinants...
July 2016: Health Security
https://www.readbyqxmd.com/read/27266983/endometrial-tuberculosis-compounding-polycystic-ovary-syndrome-in-a-subfertile-woman-a-case-report
#20
Charles Mariara, Angela Koech, Peter Waweru, Alfred Murage
BACKGROUND: Asymptomatic female genital tuberculosis can impair tubal and endometrial function and later present as subfertility. A majority of the patients with genital tuberculosis in endemic regions present with subfertility and the delay in presentation, coupled with the potential the disease has in mimicking other gynecological conditions, renders it elusive. In addition to the challenge of diagnosing genital tuberculosis, fertility outcomes after treatment are not impressive. This is particularly so in the background of another confounding subfertility factor to which interventional efforts may initially be directed, at the expense of undiagnosed genital tuberculosis...
2016: Journal of Medical Case Reports
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