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Genital tuberculosis

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https://www.readbyqxmd.com/read/29897442/latent-genital-tuberculosis-adversely-affects-the-ovarian-reserve-in-infertile-women
#1
P R Jirge, S M Chougule, A Keni, S Kumar, D Modi
STUDY QUESTION: What is the effect of latent genital tuberculosis (GTB) on ovarian reserve in infertile women? SUMMARY ANSWER: Women with latent GTB have lower ovarian reserves and yield lower numbers of oocytes in IVF. WHAT IS KNOWN ALREADY: Limited evidence suggests that women with GTB may have a low ovarian reserve. Infertile women have a high incidence of latent GTB and treatment improves fertility outcomes. STUDY DESIGN, SIZE, DURATION: This prospective study from February 2013 to January 2016 compared 431 infertile women diagnosed with latent GTB (Group I) to 453 infertile women without latent GTB (Group II)...
June 12, 2018: Human Reproduction
https://www.readbyqxmd.com/read/29879525/first-case-of-sexual-transmitted-asymptomatic-female-genital-tuberculosis-from-spousal-epididymal-tuberculosis-diagnosed-by-active-screening
#2
Muneyoshi Kimura, Hideki Araoka, Hiromi Baba, Chikako Okada, Yoshiro Murase, Akiko Takaki, Satoshi Mitarai, Akiko Yoneyama
Tuberculosis screening was performed for a healthy asymptomatic woman to determine whether she had been infected with active genital tuberculosis via sexual intercourse with her husband who had epididymal tuberculosis. Vaginal swab culture yielded Mycobacterium tuberculosis. Furthermore, whole genome sequencing revealed that the two causative isolates were genetically identical. To the best of our knowledge, this is the first report on sexual transmission of genital tuberculosis from a man to an asymptomatic woman detected by active screening for genital tuberculosis and molecular analysis, including whole-genome-sequencing...
June 4, 2018: International Journal of Infectious Diseases: IJID
https://www.readbyqxmd.com/read/29785388/genital-tuberculosis-in-postmenopausal-women-with-variable-clinical-presentations-a-report-of-3-cases
#3
Ashima Arora, Shameema Anvar Sadath
Genital tuberculosis is usually diagnosed in young women being assessed for infertility. After menopause it usually presents with symptoms resembling endometrial malignancy, such as postmenopausal bleeding, persistent vaginal discharge and pyometra. The diagnosis is made by detection of acid-fast bacilli on microscopy or bacteriological culture and/or presence of epithelioid granuloma on biopsy. Anti-tubercular therapy involves the use of rifampicin, isoniazid, pyrazinamide and ethambutol. Surgery is indicated if a pelvic mass and recurrence of pain or bleeding persist after 9 months of treatment...
April 2018: Case Reports in Women's Health
https://www.readbyqxmd.com/read/29675489/female-genital-tuberculosis-cases-with-distinct-clinical-symptoms-four-case-reports
#4
Gonul Aslan, Mahmut Ulger, Seda Tezcan Ulger, Huseyin Durukan, Faik Gurkan Yazici, Gurol Emekdas
Background: Tuberculosis (TB) is an infectious disease caused by Mycobacterium tuberculosis. Genital TB (GTB) is a form of extrapulmonary TB that occurs more frequently in women, in whom it classically presents in association with menstrual irregularity, pregnancy loss and short and long-term sequelae especially infertility in infected women. Patients with GTB are usually young women diagnosed during workup for infertility. GTB is rare in postmenopausal women and responsible for only approximately 1% of postmenopausal bleeding...
January 2018: International Journal of Reproductive Biomedicine (Yazd, Iran)
https://www.readbyqxmd.com/read/29662282/the-role-of-mgit-960-culture-medium-in-resolving-the-diagnostic-dilemma-for-genital-tuberculosis-patients-presenting-with-infertility
#5
Nidhi Jindal, Shalini Gainder, Lakhbir Kaur Dhaliwal, Sunil Sethi
Background: The purpose of this study was to assess the utility of Mycobacteria Growth Indicator Tube (MGIT) 960 culture medium for the diagnosis of genital tuberculosis (GTB) in women presenting with infertility. Methods: The premenstrual endometrial biopsy samples in 300 women presenting with primary and secondary infertility were subjected to AFB smear method, histopathological examination and culture on LJ and MGIT 960 media. Detection rates were compared for diagnostic modalities and their combinations...
April 2018: Journal of Obstetrics and Gynaecology of India
https://www.readbyqxmd.com/read/29558895/fitz-hugh-curtis-syndrome-associated-with-tuberculous-salpingitis-and-peritonitis-a-case-presentation-and-review-of-literature
#6
Laura Coremans, Frederik de Clerck
BACKGROUND: Fitz-Hugh-Curtis syndrome or acute perihepatitis is considered a rare complication of pelvic inflammatory disease, mostly associated with chlamydial or gonococcal salpingitis. Peritoneal tuberculosis is a rare site of extra-pulmonary infection caused by Mycobacterium tuberculosis. Infection usually occurs after reactivation of latent tuberculous foci in the peritoneum and more seldom after contiguous spread from tuberculous salpingitis. CASE PRESENTATION: We describe a case of a 21-year old female of Somalian origin diagnosed with Fitz-Hugh Curtis syndrome associated with tuberculous salpingitis and peritonitis, presenting with new onset ascites...
March 20, 2018: BMC Gastroenterology
https://www.readbyqxmd.com/read/29554240/epidemiology-of-hiv-sexually-transmitted-infections-viral-hepatitis-and-tuberculosis-among-incarcerated-transgender-people-a-case-of-limited-data
#7
Tonia C Poteat, Mannat Malik, Chris Beyrer
Transgender people experience a disproportionate burden of human immunodeficiency virus (HIV) and incarceration. Discrimination, victimization, poverty, and poor mental health drive vulnerability to HIV and related infections, as well as risk of arrest, detention, and incarceration. In this paper, we systematically review published data on HIV, sexually transmitted infections, viral hepatitis, and tuberculosis among incarcerated transgender people; describe potential structural determinants of HIV risk and transmission; identify gaps in the literature; and make recommendations for research and interventions to address this neglected population...
March 15, 2018: Epidemiologic Reviews
https://www.readbyqxmd.com/read/29549658/multiplex-pcr-from-menstrual-blood-a-non-invasive-cost-effective-approach-to-reduce-diagnostic-dilemma-for-genital-tuberculosis
#8
Suman K Paine, Analabha Basu, Rajib Gon Choudhury, Basudev Bhattacharya, Sidhartha Chatterjee, Chandra Bhattacharya
AIM: Genital tuberculosis (GTB) is a potent contributor to irreversible damage to the reproductive system and infertility in females. As no gold standard diagnostic tool is yet available, clinical suspicion and relatively insensitive approaches such as histopathology, laparoscopy and hysterosalpingogram are currently critical determinants in the diagnosis of GTB. Although a polymerase chain reaction (PCR)-based assay using endometrial tissue seems promising, sampling does require an invasive procedure...
June 2018: Molecular Diagnosis & Therapy
https://www.readbyqxmd.com/read/29332643/role-of-laparoscopy-in-diagnosing-genital-tuberculosis-in-suspected-women-a-cross-sectional-study-from-a-tertiary-care-hospital-in-northern-india
#9
Y M Mala, Ruchi Prasad, Nilanchali Singh, C P Baweja, Reva Tripathi, Niharika Yedla
This study was included 60 women with suspected genital tuberculosis, attending outpatient department of a tertiary care hospital. The aim was to evaluate the role and accuracy of laparoscopy in the diagnosis of genital tuberculosis. The patients were investigated for tuberculosis with Erythrocyte Sedimentation Rate, Montoux, chest X-ray, serum ELISA, CA125, ultrasonography, endometrial biopsy and laparoscopic biopsy. Culture or histopathology was taken as a gold standard for confirming the cases of genital tuberculosis...
January 2018: Indian Journal of Tuberculosis
https://www.readbyqxmd.com/read/29241916/etiology-and-management-of-primary-amenorrhoea-a-study-of-102-cases-at-tertiary-centre
#10
Alka Kriplani, Manu Goyal, Garima Kachhawa, Reeta Mahey, Vidushi Kulshrestha
OBJECTIVE: To determine the prevalence of etiologic causes of primary amenorrhea in Indian population. MATERIALS AND METHODS: A retrospective study was performed using 102 complete medical records of women with primary amenorrhea who attended the Gynaecologic Endocrinology Clinic, Department of Obstetrics and Gynaecology, AIIMS, New Delhi from September 2012 to September 2015. Cases were analysed according to clinical profile, development of secondary sexual characteristics, physical examination, pelvic and rectal examination, X-ray of chest and lumbo-sacral spine, hormone profile, pelvic USG, MRI, and cytogenetic study including karyotype...
December 2017: Taiwanese Journal of Obstetrics & Gynecology
https://www.readbyqxmd.com/read/29207705/serum-vitamin-d-level-as-a-risk-factor-for-female-genital-tuberculosis-fgtb
#11
Swati Gautam, Amita Jain, Salman Akhtar, Apala Priyadarshini, Shyam Pyari Jaiswar
Introduction: Vitamin D is now known to be essential to Mycobacterium tuberculosis containment and killing through activation of 25-hydroxyvitamin-D receptors (VDRs) present on all immune cells or obtained from dietary food stuffs as either vitamin D3 or vegetable vitamin D2 (also known as ergocalciferol). Aim: To evaluate the association of serum vitamin D level between the Female Genital Tuberculosis (FGTB) cases and healthy controls. Materials and Methods: Total 120 cases and 120 controls enrolled for the study following inclusion and exclusion criteria...
September 2017: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/29202851/female-genital-tuberculosis-and-infertility-serial-cases-report-in-bandung-indonesia-and-literature-review
#12
Tono Djuwantono, Wiryawan Permadi, Leri Septiani, Ahmad Faried, Danny Halim, Ida Parwati
BACKGROUND: Female genital tuberculosis (FGTB) is a Mycobacterium infection in the reproductive organs which often leads to infertility. FGTB is either asymptomatic or causes uncharacteristic clinical presentations, making an early diagnosis is challenging. Our aims were to evaluate the clinical presentations, the process to confirm the diagnosis and followed-up the patients who had undergone laparoscopy at our center. FGTB has been reported from many countries, but has never been reported from Indonesia...
December 4, 2017: BMC Research Notes
https://www.readbyqxmd.com/read/29135150/-chronic-course-of-latent-urogenital-tuberculosis
#13
A V Lysov, V A Okhlopkov, A V Mordyk, L V Puzyreva, E M Shestak, I G Martynov
This is a case report of an elderly patient with urogenital tuberculosis and concurrent tuberculosis of peripheral inguinal lymph nodes. The disease manifested by a fistulous form of inguinal lymphadenitis for 10 years and spread to the kidneys and genitals, but the patient did not seek medical attention. Changes on the glans penis prompted him to consult dermatovenereologist. Due to ineffective treatment and uncovering the scar in the inguinal area the patient was send to an anti-tuberculosis institution, where he was diagnosed with tuberculosis involving the kidneys, prostate, epididymis, penis, inguinal lymph nodes...
October 2017: Urologii︠a︡
https://www.readbyqxmd.com/read/29095300/rare-esophageal-ulcers-related-to-beh%C3%A3-et-disease-a-case-report
#14
Ning Jia, Yanping Tang, Huayi Liu, Yang Li, Simiao Liu, Lei Liu
RATIONALE: The fundamental pathogenesis of Behçet disease (BD) is still unclear and controversial. Many cases of oral aphthous ulcers and genital ulcers related to BD are reported; nevertheless, idiopathic giant esophageal ulcers related to BD are rare. A rare case for esophageal ulcers related to BD is presented. PATIENT CONCERNS: In China, BD is represented with esophageal involvement which is called esophageal BD (EBD). DIAGNOSES: A 56-year-old man diagnosed to the Gastroenterology Department of Integrated Traditional Chinese and Western Medicine Hospital, for multiple discrete, elliptical esophageal ulcers related to BD...
November 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29076692/genital-tuberculosis-mimicking-carcinoma-ovary-can-ultrasound-guided-biopsy-be-a-resolution
#15
Nosheen Akhtar, Zartaj Hayat, Fatima Nazim
Genital tuberculosis mimicking carcinoma ovary is a well-known dilemma as there is no definitive serological or imaging modality for diagnosing abdominopelvic tuberculosis. A 20-years-old unmarried girl presented with complex adnexal mass, mild ascites and CA 125 >1000. Her staging laparotomy and frozen section was planned. Laparotomy revealed miliary tuberculosis and frozen section confirmed the diagnosis of tuberculosis. Patient was started with anti-tuberculosis treatment and follow up showed resolution of cysts...
July 2017: Journal of Ayub Medical College, Abbottabad: JAMC
https://www.readbyqxmd.com/read/28990409/hiv-primary-care-by-the-infectious-disease-physician-in-the-united-states-extending-the-continuum-of-care
#16
Seetha Lakshmi, Susan E Beekmann, Philip M Polgreen, Allan Rodriguez, Maria L Alcaide
Models of care for people living with HIV (PLWH) have varied over time due to long term survival, development of HIV-associated non-AIDS conditions, and HIV specific primary care guidelines that differ from those of the general population. The objectives of this study are to assess how often infectious disease (ID) physicians provide primary care for PLWH, assess their practice patterns and barriers in the provision of primary care. We used a 6-item survey electronically distributed to ID physician members of Emerging Infections Network (EIN)...
May 2018: AIDS Care
https://www.readbyqxmd.com/read/28862174/genital-tuberculosis-in-females
#17
REVIEW
G Angeline Grace, D Bella Devaleenal, Mohan Natrajan
The morbidity and mortality due to tuberculosis (TB) is high worldwide, and the burden of disease among women is significant, especially in developing countries. Mycobacterium tuberculosis bacilli reach the genital tract primarily by haematogenous spread and dissemination from foci outside the genitalia with lungs as the common primary focus. Genital TB in females is a chronic disease with low-grade symptoms. The fallopian tubes are affected in almost all cases of genital TB, and along with endometrial involvement, it causes infertility in patients...
April 2017: Indian Journal of Medical Research
https://www.readbyqxmd.com/read/28820423/-risk-factors-and-special-aspects-forgenital-tuberculosis-diagnostics
#18
G Lortkipanidze, N Kintraia, K Vacharadze, F Tsaava
Was examined 453 women, who applied to National Center for Tuberculosis and Lung Diseases for genital tuberculosis diagnostics. GTB was detected in 289 cases, in 164 cases GTB results was negative (control group). In 10 cases GTB was combined with pulmonary tuberculosis (OR-1,13). Risk factors are previous diseases of female reproductive organs- intracellular infection (OR-1,08), sexually transmitted diseases (OR-1,25), nonspecific inflammatory diseases (OR-1,009), interruption of pregnancy (OR-1,26), artificial abortions (OR-1,11), the most specific signs of Genital Tuberculosis is a pain in the stomach area (P-0,023), dysmenorrhoea (P-0,00001), intestinal obstruction (P-0,0006), heat (P-0,00001), liquid presence in posterior vault (P-0,007), hydrosalpinx (P-0,00001), Fallopian tubes deformation (P-0,000003), oophoritic cyst (P-0,067), adhesive process in small pelvis (P-0,0006)...
July 2017: Georgian Medical News
https://www.readbyqxmd.com/read/28808611/red-snappers-and-red-herrings-pelvic-tuberculosis-causing-elevated-ca-125-and-mimicking-advanced-ovarian-cancer-a-case-report-and-literature-review
#19
Johnnie Alphonse Yates, Olivia Ann Collis, Thanasak Sueblinvong, Tarquin Kamakana Collis
Female genital tuberculosis (FGTB) is a form of extra-pulmonary tuberculosis that has been primarily described in developing countries, where it is an important cause of infertility, ectopic pregnancy, and miscarriage. FGTB is rare in the United States and because its clinical presentation is non-specific and often insidious, FGTB may be misdiagnosed as a gynecologic malignancy or endometriosis. The tendency of tuberculosis to dramatically increase serum CA 125 levels contributes to the potential for FGTB to be mistaken for ovarian cancer in particular...
August 2017: Hawai'i Journal of Medicine & Public Health: a Journal of Asia Pacific Medicine & Public Health
https://www.readbyqxmd.com/read/28709484/concomitant-female-genital-tuberculosis-and-endometriosis
#20
Jai Bhagwan Sharma, Manu Goyal, Sunesh Kumar, Kallol Kumar Roy, Eshani Sharma, Raksha Arora
AIMS: To demonstrate an association between female genital tuberculosis (FGTB) and endometriosis. METHODS: A total of 16 women who underwent laparoscopy (12 cases) or laparotomy (4 cases) and were found to have female genital tuberculosis and endometriosis were enrolled in this retrospective study. RESULTS: The mean age and parity were 28.2 years and 0.2, respectively. Past history of tuberculosis was present in 75% of the women (pulmonary in 50%)...
July 2017: Indian Journal of Tuberculosis
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