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H D White, N Goenka, N J Furlong, S Saunders, G Morrison, P Langridge, P Paul, A Ghatak, P J Weston
AIMS: The National Institute for Health and Clinical Excellence (NICE) published guidelines for the use of continuous subcutaneous insulin infusion in 2008 (technology appraisal 151). The first U.K.-wide insulin pump audit took place in 2012 with the aim of determining adherence to the guidance issued in NICE technology appraisal 151. The results of the adult service level audit are reported here. METHODS: All centres providing continuous subcutaneous insulin infusion services to adults with diabetes in the U...
April 2014: Diabetic Medicine: a Journal of the British Diabetic Association
Ralf Schiel, Sebastian Heinrich, Thomas Steiner, Undine Ott, G√ľnter Stein
BACKGROUND: Compared with non-diabetic subjects, patients with type 2 diabetes and end-stage renal disease (ESRD) have seldom been selected for renal transplantation. It was the aim of this study to compare the long-term prognoses of the two groups of patients after transplantation and to identify factors associated with allograft rejection. METHODS: In a retrospective analysis, we studied all 333 consecutive patients who received a kidney transplant at our centre since 1992...
March 2005: Nephrology, Dialysis, Transplantation
J Fowelin, S Attvall, H von Schenck, U Smith, I Lager
The insulin effect (6.5 to 7.5 hours) following hypoglycemia was studied with the euglycemic clamp technique in eight patients with insulin-dependent diabeteses mellitus (IDDM). The results were compared with a control study with the same insulin infusion, but where hypoglycemia was prevented by a glucose infusion. Glucose production (Ra) and utilization (Rd) were evaluated with D-(3-3H) glucose infusion. Hypoglycemia (glucose nadir, 1.5 +/- 0.1 mmol/L) caused a marked increase in cortisol and growth hormone, whereas the release of adrenaline and, in particular, glucagon was low...
August 1990: Metabolism: Clinical and Experimental
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