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https://www.readbyqxmd.com/read/28427597/intentional-percutaneous-laceration-of%C3%A2-the%C3%A2-anterior-mitral-leaflet-to-prevent%C3%A2-outflow%C3%A2-obstruction-during-transcatheter-mitral-valve-replacement-first-in-human%C3%A2-experience
#1
Vasilis C Babaliaros, Adam B Greenbaum, Jaffar M Khan, Toby Rogers, Dee Dee Wang, Marvin H Eng, William W O'Neill, Gaetano Paone, Vinod H Thourani, Stamatios Lerakis, Dennis W Kim, Marcus Y Chen, Robert J Lederman
OBJECTIVES: This study sought to use a new catheter technique to split the anterior mitral valve leaflet (AML) and prevent iatrogenic left ventricular outflow tract (LVOT) obstruction immediately before transcatheter mitral valve replacement (TMVR). BACKGROUND: LVOT obstruction is a life-threatening complication of TMVR, caused by septal displacement of the AML. METHODS: The procedure was used in patients with severe mitral valve disease and prohibitive surgical risk...
April 24, 2017: JACC. Cardiovascular Interventions
https://www.readbyqxmd.com/read/28424229/tension-activated-channels-in-the-mechanism-of-osmotic-fitness-in-pseudomonas-aeruginosa
#2
Uğur Çetiner, Ian Rowe, Anthony Schams, Christina Mayhew, Deanna Rubin, Andriy Anishkin, Sergei Sukharev
Pseudomonas aeruginosa (PA) is an opportunistic pathogen with an exceptional ability to adapt to a range of environments. Part of its adaptive potential is the ability to survive drastic osmolarity changes. Upon a sudden dilution of external medium, such as during exposure to rain, bacteria evade mechanical rupture by engaging tension-activated channels that act as osmolyte release valves. In this study, we compare fast osmotic permeability responses in suspensions of wild-type PA and Escherichia coli (EC) strains in stopped-flow experiments and provide electrophysiological descriptions of osmotic-release channels in PA...
April 19, 2017: Journal of General Physiology
https://www.readbyqxmd.com/read/28390614/coblation-of-suprastomal-granulomas-in-tracheostomy-dependent-children
#3
C Scott Brown, Marisa A Ryan, Vaibhav H Ramprasad, Anatoli F Karas, Eileen M Raynor
OBJECTIVE: Suprastomal granulomas pose a persistent challenge for tracheostomy-dependent children. They can limit phonation, cause difficulty with tracheostomy tube changes and prevent decannulation. We describe the use of the coblator for radiofrequency plasma ablation of suprastomal granulomas in five consecutive children from September 2012 to January 2016. METHOD: Retrospective case series at a tertiary medical center. RESULTS: The suprastomal granuloma could be removed with the coblator in all 5 cases...
May 2017: International Journal of Pediatric Otorhinolaryngology
https://www.readbyqxmd.com/read/28382264/use-of-cardiac-computed-tomography-for-ventricular-volumetry-in-late-postoperative-patients-with-tetralogy-of-fallot
#4
Ho Jin Kim, Da Na Mun, Hyun Woo Goo, Tae-Jin Yun
BACKGROUND: Cardiac computed tomography (CT) has emerged as an alternative to magnetic resonance imaging (MRI) for ventricular volumetry. However, the clinical use of cardiac CT requires external validation. METHODS: Both cardiac CT and MRI were performed prior to pulmonary valve implantation (PVI) in 11 patients (median age, 19 years) who had undergone total correction of tetralogy of Fallot during infancy. The simplified contouring method (MRI) and semiautomatic 3-dimensional region-growing method (CT) were used to measure ventricular volumes...
April 2017: Korean Journal of Thoracic and Cardiovascular Surgery
https://www.readbyqxmd.com/read/28340650/functional-rhinoplasty
#5
REVIEW
Oren Friedman, Erdinc Cekic, Ceren Gunel
Understanding nasal anatomy and physiology are the most important points for successful functional rhinoplasty. Anatomic structures playing major roles in nasal breathing functions include the septum, and internal and external nasal valves, so physical examination of these regions is essential. Planning for functional rhinoplasty involves the identification of the sites of nasal airway obstruction or old trauma, and addressing those regions during the operation with a number of different techniques that have been described...
May 2017: Facial Plastic Surgery Clinics of North America
https://www.readbyqxmd.com/read/28340649/the-external-nasal-valve
#6
REVIEW
Grant S Hamilton
The external nasal valve is a complex entity comprised of multiple structures and tissue types. As such, there is no single operation that can address all problems of the external valve. This article reviews the relevant anatomy, pathologic conditions, and treatments for external nasal valve dysfunction, including a detailed review of the nasal muscles and their contribution to external nasal valve patency. Surgical and nonsurgical options for treatment and the evidence supporting the importance of proper external nasal valve function on quality-of-life measures are discussed...
May 2017: Facial Plastic Surgery Clinics of North America
https://www.readbyqxmd.com/read/28301627/single-staged-tunneled-cheek-interpolation-flap-with-cartilage-batten-graft-for-repair-of-nasal-ala-defect
#7
Tatyana A Petukhova, Jayne S Joo, Daniel B Eisen
<p>Surgical defects located within 5 mm of the nasal alar margin are at risk for alar elevation or collapse of the external nasal valve during wound healing. To reduce the chance of such complications, free cartilage grafts may be used as part of the reconstruction. However, if the defect is large enough so that the free cartilage graft does not fill most of the defect, wound contraction can still lead to alar displacement. In these situations, skin may need to be recruited from either the forehead or cheek in the form of an interpolation flap to cover both the free cartilage graft and the residual cutaneous defect...
March 1, 2017: Journal of Drugs in Dermatology: JDD
https://www.readbyqxmd.com/read/28278526/-acute-kidney-failure-due-to-urachal-cyst
#8
I Klaassen, M Wolf, M J Kemper, S Riechardt, M Boettcher, J Herrmann, D Singer
A 34-year-old para V woman was referred to our centre at 35+1 weeks of gestation for an assumed fetal malformation with prenatal renal impairment and anhydramnios. Prenatal ultrasound demonstrated unilateral renal agenesis; the bladder was not detectable. The baby was born by caesarian section at 36+2 weeks of gestation because of placental insufficiency. Postnatal adaptation was uneventful, but the newborn presented external stigmas of trisomy 21 and progressive renal impairment with anuria. Nevertheless, the postnatal ultrasound showed two enlarged kidneys in loco typico with impaired perfusion but without signs of malformations...
March 9, 2017: Zeitschrift Für Geburtshilfe und Neonatologie
https://www.readbyqxmd.com/read/28274588/unilateral-absence-of-an-external-jugular-vein-in-two-english-bulldogs-with-pulmonary-valve-stenosis
#9
E H Chapel, B A Scansen
Two English bulldogs referred for interventional palliation of severe pulmonary valve stenosis were incidentally diagnosed with unilateral absence of an external jugular vein (left in one case, right in the other) by computed tomography and Doppler ultrasound. The right internal jugular vein also could not be visualized in the dog with absence of the left external jugular vein. Cervical venous anomalies can impact diagnostic or interventional venous catheterization procedures such as balloon pulmonary valvuloplasty...
March 5, 2017: Journal of Veterinary Cardiology: the Official Journal of the European Society of Veterinary Cardiology
https://www.readbyqxmd.com/read/28268511/tracking-of-the-anterior-mitral-leaflet-in-echocardiographic-sequences-using-active-contours
#10
Malik Saad Sultan, Nelson Martins, Diana Veiga, Manuel Joao Ferreira, Miguel Tavares Coimbra
Echocardiography assessment of cardiac valves plays a vital role in the diagnosis of rheumatic heart disease. In the vast majority of cases, the mitral valve gets affected, leading to the thickening of its leaflets that may result in the fusion of their tips. This changes the appearance and reduces the mobility of the leaflets, which also reduce the heart efficiency. Quantifying such parameters provides diagnostic insight. To achieve that, the first step is to identify and then track fast moving leaflets. This work is focused on Anterior Mitral Leaflet (AML) tracking...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28248486/stimuli-responsive-dna-based-hydrogels-from-basic-principles-to-applications
#11
Jason S Kahn, Yuwei Hu, Itamar Willner
The base sequence of nucleic acids encodes structural and functional information into the DNA biopolymer. External stimuli such as metal ions, pH, light, or added nucleic acid fuel strands provide triggers to reversibly switch nucleic acid structures such as metal-ion-bridged duplexes, i-motifs, triplex nucleic acids, G-quadruplexes, or programmed double-stranded hybrids of oligonucleotides (DNA). The signal-triggered oligonucleotide structures have been broadly applied to develop switchable DNA nanostructures and DNA machines, and these stimuli-responsive assemblies provide functional scaffolds for the rapidly developing area of DNA nanotechnology...
March 1, 2017: Accounts of Chemical Research
https://www.readbyqxmd.com/read/28236098/use-of-extracorporeal-membrane-oxygenation-in-complicated-transcatheter-aortic-valve-replacement
#12
Kyokun Uehara, Kenji Minakata, Naritatsu Saito, Masao Imai, Hiroki Daijo, Taro Nakatsu, Kazuhisa Sakamoto, Kazuhiro Yamazaki, Takeshi Kimura, Ryuzo Sakata
OBJECTIVES: Although transcatheter aortic valve replacement (TAVR) is an excellent alternative procedure for high-risk patients with severe symptomatic aortic stenosis, it is often associated with life-threatening complications. We report on the emergency or elective use of veno-arterial extracorporeal membrane oxygenation (ECMO) to manage these complications. METHODS: Between December 2013 and February 2016, 46 patients underwent TAVR at our institution. Of these, 4 patients required emergency ECMO support and another 3 patients were electively placed on ECMO support at the start of the procedure...
February 24, 2017: General Thoracic and Cardiovascular Surgery
https://www.readbyqxmd.com/read/28230600/nasal-valve-collapse-our-treatment-protocol
#13
Giulia Amodeo, Domenico Scopelliti
The nasal valve area is the functional area that allows airflow regulation. It could be divided in an internal area and an external one, basing on the anatomical landmarks. Many conditions can damage these areas with a consequently nasal obstruction, more often in particular extended rhinoplasty and sequels of facial trauma. To restore this area many techniques were advocated during the last decades.In this article the authors investigate on valve areas deficiency in sequel of rhinoplasty proposing a structural approach through alar batten grafts to correct internal-external nasal valves collapse...
February 22, 2017: Journal of Craniofacial Surgery
https://www.readbyqxmd.com/read/28226685/tracking-of-the-anterior-mitral-leaflet-in-echocardiographic-sequences-using-active-contours
#14
Malik Saad Sultan, Nelson Martins, Diana Veiga, Manuel Joao Ferreira, Miguel Tavares Coimbra, Malik Saad Sultan, Nelson Martins, Diana Veiga, Manuel Joao Ferreira, Miguel Tavares Coimbra, Diana Veiga, Nelson Martins, Malik Saad Sultan, Miguel Tavares Coimbra, Manuel Joao Ferreira
Echocardiography assessment of cardiac valves plays a vital role in the diagnosis of rheumatic heart disease. In the vast majority of cases, the mitral valve gets affected, leading to the thickening of its leaflets that may result in the fusion of their tips. This changes the appearance and reduces the mobility of the leaflets, which also reduce the heart efficiency. Quantifying such parameters provides diagnostic insight. To achieve that, the first step is to identify and then track fast moving leaflets. This work is focused on Anterior Mitral Leaflet (AML) tracking...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28219192/-efficacy-comparison-of-interventional-treatment-by-anterograde-or-retrograde-catheterization-for-acute-lower-extremity-deep-venous-thrombosis
#15
G P Chen, J P Gu, X He, W S Lou, Y Wang, L Chen, H B Su, W Y Shi, T Wang
Objective: To compare the clinical efficacy differences between anterograde and retrograde catheterization interventional treatment for acute low extremity deep venous thrombosis(DVT). Methods: The clinical data of 217 patients with acute low extremity DVT between January 2009 and December 2014 were analyzed retrospectively. Group A: 67 patients underwent treated with anterograde catheterization interventional treatment. Group B: 150 patients underwent treated with retrograde catheterization interventional treatment...
February 7, 2017: Zhonghua Yi Xue za Zhi [Chinese medical journal]
https://www.readbyqxmd.com/read/28187973/remodeling-root-repair-with-an-external-aortic-ring-annuloplasty
#16
Emmanuel Lansac, Isabelle Di Centa, Ghassan Sleilaty, Stephanie Lejeune, Alain Berrebi, Pavel Zacek, Mathieu Debauchez
OBJECTIVE: Although the remodeling technique provides the most dynamic valve-sparing root replacement, a dilated annulus (>25 mm) is a risk factor for failure. Aortic annuloplasty aims to reduce the annulus diameter, thus increasing coaptation height to protect the repair. The results of 177 patients with remodeling and external aortic ring annuloplasty were studied. METHODS: Data were collected from the Aortic Valve repair InternATiOnal Registry. Preoperative aortic insufficiency grade 3 or greater was present in 79 patients (44...
May 2017: Journal of Thoracic and Cardiovascular Surgery
https://www.readbyqxmd.com/read/28181607/robust-temperature-change-rate-actuated-valving-and-switching-for-highly-integrated-centrifugal-microfluidics
#17
M Keller, G Czilwik, J Schott, I Schwarz, K Dormanns, F von Stetten, R Zengerle, N Paust
We present new unit operations for valving and switching in centrifugal microfluidics that are actuated by a temperature change rate (TCR) and controlled by the rotational frequency. Implementation is realized simply by introducing a comparatively large fluidic resistance to an air vent of a fluidic structure downstream of a siphon channel. During temperature decrease at a given TCR, the air pressure inside the downstream structure decreases and the fluidic resistance of the air vent slows down air pressure compensation allowing a thermally induced underpressure to build up temporarily...
February 9, 2017: Lab on a Chip
https://www.readbyqxmd.com/read/28179104/variations-in-structure-of-the-outflow-tract-of-the-human-embryonic-heart-a-new-hypothesis-for-generating-bicuspid-aortic-semilunar-valves
#18
Nadine C Milos, Derek B Nordstrom, Ivano Ongaro, Ava K Chow
Outflow tract development of the heart is complex. The presence, differential growth and interactions of the various tissues through space and time contribute to the final development of the tract. This paper presents a novel interpretation of observations of outflow tract development, in particular of the aortic and pulmonary semilunar valves in embryos from the Shaner Collection at the University of Alberta. Three-dimensional reconstructions assist in the visualization of the spatial relationships of the developing valve tissues...
February 4, 2017: Annals of Anatomy, Anatomischer Anzeiger: Official Organ of the Anatomische Gesellschaft
https://www.readbyqxmd.com/read/28167498/myocardial-oxygen-consumption-and-efficiency-in-aortic-valve-stenosis-patients-with-and-without-heart-failure
#19
Nils Henrik Stubkjær Hansson, Jens Sörensen, Hendrik Johannes Harms, Won Yong Kim, Roni Nielsen, Lars P Tolbod, Jørgen Frøkiær, Kirsten Bouchelouche, Karen Kaae Dodt, Inger Sihm, Steen Hvitfeldt Poulsen, Henrik Wiggers
BACKGROUND: Myocardial oxygen consumption (MVO2) and its coupling to contractile work are fundamentals of cardiac function and may be involved causally in the transition from compensated left ventricular hypertrophy to failure. Nevertheless, these processes have not been studied previously in patients with aortic valve stenosis (AS). METHODS AND RESULTS: Participants underwent (11)C-acetate positron emission tomography, cardiovascular magnetic resonance, and echocardiography to measure MVO2 and myocardial external efficiency (MEE) defined as the ratio of left ventricular stroke work and the energy equivalent of MVO2...
February 6, 2017: Journal of the American Heart Association
https://www.readbyqxmd.com/read/28164025/pulmonary-autograft-in-aortic-position-is-everything-known
#20
COMMENT
Francesco Nappi, Antonio Nenna, Cristiano Spadaccio, Massimo Chello
The Ross operation provides several advantages compared to other valve substitutes to manage aortic valve disease, such as growth potential, excellent hemodynamics, freedom from oral anticoagulation and hemolysis, and better durability. However, progressive dilatation of the pulmonary autografts after Ross operation reflects the inadequate remodeling of the native pulmonary root in the systemic circulation, which results in impaired adaptability to systemic pressure and risk of reoperation after the first decade...
January 2017: Translational pediatrics
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