keyword
MENU ▼
Read by QxMD icon Read
search

External valve

keyword
https://www.readbyqxmd.com/read/28092382/a-vascularized-and-perfused-organ-on-a-chip-platform-for-large-scale-drug-screening-applications
#1
Duc T T Phan, Xiaolin Wang, Brianna M Craver, Agua Sobrino, Da Zhao, Jerry C Chen, Lilian Y N Lee, Steven C George, Abraham P Lee, Christopher C W Hughes
There is a growing awareness that complex 3-dimensional (3D) organs are not well represented by monolayers of a single cell type - the standard format for many drug screens. To address this deficiency, and with the goal of improving screens so that drugs with good efficacy and low toxicity can be identified, microphysiological systems (MPS) are being developed that better capture the complexity of in vivo physiology. We have previously described an organ-on-a-chip platform that incorporates perfused microvessels, such that survival of the surrounding tissue is entirely dependent on delivery of nutrients through the vessels...
January 16, 2017: Lab on a Chip
https://www.readbyqxmd.com/read/28033641/optimizing-the-soft-tissue-triangle-alar-margin-furrow-and-alar-ridge-aesthetics-analysis-and-use-of-the-articulate-alar-rim-graft
#2
Jennifer L Goodrich, B J F Wong
The alar lobule, alar margin, and soft triangle facet are receiving more attention in the literature as critical elements to address both preoperatively and during rhinoplasty. We have found that the use of the articulated alar rim graft (AARG) corrects deficiencies in these areas as well as provides mechanical stability to the external valve. In this article, we describe indications for AARG, describe in detail the procedure for AARG placement, and highlight the transformation AARGs can achieve in two illustrated case studies...
December 2016: Facial Plastic Surgery: FPS
https://www.readbyqxmd.com/read/28009195/nanoelectromechanical-heat-engine-based-on-electron-electron-interaction
#3
A Vikström, A M Eriksson, S I Kulinich, L Y Gorelik
We theoretically show that a nanoelectromechanical system can be mechanically actuated by a heat flow through it via an electron-electron interaction. In contrast to most known actuation mechanisms in similar systems, this new mechanism does not involve an electronic current nor external ac fields. Instead, the mechanism relies on deflection-dependent tunneling rates and a heat flow which is mediated by an electron-electron interaction while an electronic current through the device is prohibited by, for instance, a spin-valve effect...
December 9, 2016: Physical Review Letters
https://www.readbyqxmd.com/read/28005655/columellar-reconstruction-after-nasal-continuous-positive-airway-pressure-associated-necrosis
#4
Jerry W Chao, Janani A Raveendran, Tina M Sauerhammer, Gary F Rogers, Albert K Oh, Michael Boyajian
Though a life-saving modality in neonatal intensive care units, nasal continuous positive airway pressure (nCPAP) carries a small risk of irreversible ischemia and necrosis of the columella due to the configuration of the pressure delivery system. Iatrogenic injuries to the columella after nCPAP use result in a spectrum of disfigurement and functional airway obstruction. The authors performed a retrospective review of patients evaluated for nCPAP-related columellar deformities by the Division of Plastic and Reconstructive Surgery at the authors' institution over a 10-year period to assess reconstructive outcomes...
December 21, 2016: Journal of Craniofacial Surgery
https://www.readbyqxmd.com/read/28001132/geometrical-control-of-pure-spin-current-induced-domain-wall-depinning
#5
Alexander Pfeiffer, Robert Reeve, Michele Voto, Williams Savero Torres, Nils Richter, Laurent Vila, Jean-Philippe Attane, Luis Diaz, Mathias Kläui
We investigate the pure spin-current assisted depinning of magnetic domain walls in half ring based Py/Al lateral spin valve structures. Our optimized geometry incorporating a patterned notch in the detector electrode, directly below the Al spin conduit, provides a tailored pinning potential for a transverse domain wall and allows for a precise control over the magnetization configuration and as a result the domain wall pinning. Due to the patterned notch, we are able to study the depinning field as a function of the applied external field for certain applied current densities and observe a clear asymmetry for the two opposite field directions...
December 21, 2016: Journal of Physics. Condensed Matter: An Institute of Physics Journal
https://www.readbyqxmd.com/read/27993741/spinal-intradural-arachnoid-webs-causing-spinal-cord-compression-with-inconclusive-preoperative-imaging-a-report-of-three-cases-and-a-review-of-the-literature
#6
Dafang Zhang
OBJECTIVE: Spinal arachnoid webs are a rare variant of spinal arachnoid cysts where one or multiple focal membranes of arachnoid tissue obstruct the subarachnoid space. Only 11 prior cases of arachnoid webs have been reported in the literature. Our objective is to present a series of three consecutive cases of arachnoid webs from our institution and to review the literature on this rare condition to provide recommendations for its management. METHODS: A retrospective chart review was performed for three consecutive cases of intradural arachnoid webs causing spinal cord compression at our institution, with inconclusive preoperative imaging, treatment with surgical decompression and resection...
December 16, 2016: World Neurosurgery
https://www.readbyqxmd.com/read/27987617/determining-the-origin-of-superficial-venous-reflux-in-the-groin-with-duplex-ultrasound-and-implications-for-varicose-vein-surgery
#7
Paul Zollmann, Christine Zollmann, Philipp Zollmann, Juergen Veltman, Dennis Kerzig, Martin Doerler, Markus Stücker
OBJECTIVE: The purpose of this paper was to describe patterns of superficial reflux in the groin with respect to the terminal valve (TV), which is located at the saphenous opening to the common femoral vein, the great saphenous vein, and its tributary veins. METHODS: This study included 2019 legs with chronic venous insufficiency that received endoluminal varicose vein treatment because of varicosities with insufficiency of the saphenofemoral junction (SFJ). In a preoperative duplex ultrasound investigation of the superficial vein system, reflux after provocation in the SFJ, great saphenous vein, cranial veins (superficial external pudendal vein, superficial epigastric vein, superficial circumflex iliac vein), and anterior and posterior accessory saphenous veins was recorded and classified on the basis of the origin of reflux...
January 2017: Journal of Vascular Surgery. Venous and Lymphatic Disorders
https://www.readbyqxmd.com/read/27980283/pure-cusp-tear-of-trifecta-bioprosthesis-2-years-after-aortic-valve-replacement
#8
Masaki Hamamoto, Taira Kobayashi, Masamichi Ozawa, Kosuke Yoshimura
Trifecta is a stented bioprosthetic heart valve with a bovine pericardial sheet externally mounted on a titanium stent. This valve is applied only for aortic valve replacement (AVR), providing excellent hemodynamics and extremely low incidence of structural valve deterioration (SVD). A 76-year-old woman presented with dyspnea on effort 24 months after AVR with a 21-mm Trifecta valve. Echocardiography revealed severe aortic regurgitation with prolapse of a cusp of Trifecta valve, which suggested that she developed acute heart failure due to early SVD...
December 14, 2016: Annals of Thoracic and Cardiovascular Surgery
https://www.readbyqxmd.com/read/27965932/valve-sparing-root-replacement-aortic-root-remodeling-with-external-subvalvular-ring-annuloplasty
#9
Sang-Ho Cho, Dae Hyun Kim, Young Tae Kwak
The original valve-sparing procedures for aortic root aneurysms were remodeling and reimplantation of the aortic root. The remodeling technique provides more physiologic movement of the cusps within 3 reconstructed neo-sinuses, thus preserving root expansibility through the interleaflet triangles. However, the durability of remodeling has been a matter of concern due to the high rate of aortic insufficiency when annular dilation is not addressed. Therefore, a modified approach was developed, combining a physiologic remodeling of the root with a subvalvular annuloplasty...
December 2016: Korean Journal of Thoracic and Cardiovascular Surgery
https://www.readbyqxmd.com/read/27964975/midterm-multicenter-clinical-and-hemodynamic-results-for-the-trifecta-aortic-pericardial-valve
#10
Scott Goldman, Anson Cheung, Joseph E Bavaria, Michael R Petracek, Mark A Groh, Hartzell V Schaff
OBJECTIVE: To evaluate the midterm hemodynamic performance and clinical outcomes of the Trifecta aortic pericardial valve. METHODS: In a multicenter, prospective, nonrandomized, follow-up study, 710 patients underwent surgical implantation of a pericardial stented aortic prosthesis (Trifecta valve; St Jude Medical, St. Paul, Minn). The valve is constructed from bovine pericardium mounted externally onto a titanium stent. Subjects were followed on an annual basis over 6 years...
November 18, 2016: Journal of Thoracic and Cardiovascular Surgery
https://www.readbyqxmd.com/read/27899119/clinical-outcome-and-hemodynamic-behavior-of-the-labcor-dokimos-plus-aortic-valve
#11
Torsten Christ, Konstantin Zhigalov, Wolfgang Konertz, Sebastian Holinski
BACKGROUND: The Labcor Dokimos Plus (LDP) is a stented externally mounted pericardial aortic bioprosthesis, which was recently introduced in Europe. Aims of the study are evaluation of operative and postoperative results as well as hemodynamic performance. METHODS: One hundred consecutive patients with a mean age of 65.9 ± 10.7 years (range 35-87) and a mean EuroSCORE II of 3.1 ± 3.9 (range 0.67-24.5) underwent aortic valve replacement with the LDP. Mean valve-size was 25...
November 29, 2016: Journal of Cardiothoracic Surgery
https://www.readbyqxmd.com/read/27866864/anatomical-histochemical-and-immunohistochemical-characterisation-of-the-cardiac-outflow-tract-of-the-silver-arowana-osteoglossum-bicirrhosum-teleostei-osteoglossiformes
#12
Miguel Lorenzale, Miguel A López-Unzu, M Carmen Fernández, Ana C Durán, Borja Fernández, M Teresa Soto-Navarrete, Valentín Sans-Coma
The cardiac outflow tract of chondrichthyans and actinopterygians is composed of a myocardial conus arteriosus and a non-myocardial bulbus arteriosus. In teleosts, the conus has been subjected to a reduction in size over the evolution in conjunction with the further development of the bulbus. Most studies on the outflow tract of the teleost heart refer to species of modern groups and are mainly devoted to the bulbus. Knowledge on the outflow tract of species belonging to early teleost groups is scarce. The aim here was to characterise the structure of the cardiac outflow tract of the silver arowana, a representative of the ancient teleost clade of the Osteoglossomorpha...
September 28, 2016: Zoology: Analysis of Complex Systems, ZACS
https://www.readbyqxmd.com/read/27866824/detection-of-her2-overexpressing-cancer-cells-using-keyhole-shaped-chamber-array-employing-a-magnetic-droplet-handling-system
#13
Mina Okochi, Shinji Koike, Masayoshi Tanaka, Hiroyuki Honda
An on-chip gene expression analysis compartmentalized in droplets was developed for detection of cancer cells at a single-cell level. The chip consists of a keyhole-shaped reaction chamber with hydrophobic modification employing a magnetic bead-droplet-handling system with a gate for bead separation. Using three kinds of water-based droplets in oil, a droplet with sample cells, a lysis buffer with magnetic beads, and RT-PCR buffer, parallel magnetic manipulation and fusion of droplets were performed using a magnet-handling device containing small external magnet patterns in an array...
November 11, 2016: Biosensors & Bioelectronics
https://www.readbyqxmd.com/read/27847065/an-option-for-concomitant-management-of-moderate-marfan-root-aneurysm-at-the-time-of-mitral-valve-repair-a-role-for-personalized-external-aortic-root-support
#14
Umberto Benedetto, Xu Yu Jin, Elaine Hill, Tom Treasure, Mario Petrou
Two patients had mitral valve repair for severe regurgitation in the presence of a Marfan aortic root aneurysm. Concomitant personalized external aortic root support was used at the same operation to halt aneurysm progression and to correct mild aortic regurgitation.
December 2016: Annals of Thoracic Surgery
https://www.readbyqxmd.com/read/27826462/reconstruction-of-alar-nasal-cartilage-defects-using-a-tissue-engineering-technique-based-on-a-combined-use-of-autologous-chondrocyte-micrografts-and-platelet-rich-plasma-preliminary-clinical-and-instrumental-evaluation
#15
Pietro Gentile, Maria G Scioli, Alessandra Bielli, Augusto Orlandi, Valerio Cervelli
BACKGROUND: Developing cartilage constructs with injectability, appropriate matrix composition, and persistent cartilaginous phenotype remains an enduring challenge in cartilage repair. The combined use of autologous chondrocyte micrografts and platelet-rich plasma (PRP) is an alternative that opens a new era in this field. METHODS: At the Department of Plastic and Reconstructive Surgery, University of Rome Tor Vergata, Italy, 11 patients underwent nasal alar reconstruction with chondrocyte micrografts gently poured onto PRP in solid form...
October 2016: Plastic and Reconstructive Surgery. Global Open
https://www.readbyqxmd.com/read/27797384/transient-microfluidic-compartmentalization-using-actionable-microfilaments-for-biochemical-assays-cell-culture-and-organs-on-chip
#16
Ayako Yamada, Renaud Renault, Aleksandra Chikina, Bastien Venzac, Iago Pereiro, Sylvie Coscoy, Marine Verhulsel, Maria Carla Parrini, Catherine Villard, Jean-Louis Viovy, Stéphanie Descroix
We report here a simple yet robust transient compartmentalization system for microfluidic platforms. Cylindrical microfilaments made of commercially available fishing lines are embedded in a microfluidic chamber and employed as removable walls, dividing the chamber into several compartments. These partitions allow tight sealing for hours, and can be removed at any time by longitudinal sliding with minimal hydrodynamic perturbation. This allows the easy implementation of various functions, previously impossible or requiring more complex instrumentation...
October 31, 2016: Lab on a Chip
https://www.readbyqxmd.com/read/27788941/long-term-outcomes-of-external-repair-as-a%C3%A2-rescue-operation-for-atrioventricular-groove-disruption
#17
Nikola Dobrilovic, Jaishankar Raman, James G Fingleton, Andrew Maslow, Arun K Singh
BACKGROUND: Atrioventricular groove disruption (AVGD) is an uncommon but lethal complication of mitral valve operations associated with mortality approaching 90%. Traditionally, an "internal" repair is performed requiring prosthesis explantation, complete atrioventricular groove reconstruction using a patch positioned from within the cardiac cavity, and subsequent prosthesis reimplantation. This is a massive undertaking that is usually unsuccessful. We examine the utility of an alternative, "external" approach for rescue of AVGD...
October 24, 2016: Annals of Thoracic Surgery
https://www.readbyqxmd.com/read/27765189/prediction-of-poor-outcome-after-transcatheter-aortic-valve-replacement
#18
Suzanne V Arnold, Jonathan Afilalo, John A Spertus, Yuanyuan Tang, Suzanne J Baron, Philip G Jones, Michael J Reardon, Steven J Yakubov, David H Adams, David J Cohen
BACKGROUND: A series of models have been developed to identify patients at high risk for poor outcomes after transcatheter aortic valve replacement (TAVR) to help guide treatment choices, offer patients realistic expectations of long-term outcomes, and support decision making. OBJECTIVES: This study examined the performance of the previously developed TAVR Poor Outcome risk models in an external dataset and explored the incremental contribution of geriatric domains to model performance...
October 25, 2016: Journal of the American College of Cardiology
https://www.readbyqxmd.com/read/27720172/nonlinear-model-predictive-control-applied-to-the-separation-of-praziquantel-in-simulated-moving-bed-chromatography
#19
A S Andrade Neto, A R Secchi, M B Souza, A G Barreto
An adaptive nonlinear model predictive control of a simulated moving bed unit for the enantioseparation of praziquantel is presented. A first principle model was applied at the proposed purity control scheme. The main concern about this kind of model in a control framework is in regard to the computational effort to solve it; however, a fast enough solution was achieved. In order to evaluate the controller's performance, several cases were simulated, including external pumps and switching valve malfunctions...
September 30, 2016: Journal of Chromatography. A
https://www.readbyqxmd.com/read/27713988/magnetic-adhesive-based-valves-for-microfluidic-devices-used-in-low-resource-settings
#20
Jason C Harper, Jenna M Andrews, Candice Ben, Andrew C Hunt, Jaclyn K Murton, Bryan D Carson, George D Bachand, Julie A Lovchik, William D Arndt, Melissa R Finley, Thayne L Edwards
Since the introduction of micro total analytical systems (μTASs), significant advances have been made toward development of lab-on-a-chip platforms capable of performing complex biological assays that can revolutionize public health, among other applications. However, use of these platforms in low-resource environments (e.g. developing countries) has yet to be realized as the majority of technologies used to control microfluidic flow rely on off-device hardware with non-negligible size, cost, power requirements and skill/training to operate...
October 18, 2016: Lab on a Chip
keyword
keyword
104773
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"