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Lumbar disc herniation

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https://www.readbyqxmd.com/read/28224214/predictors-of-the-outcome-of%C3%A2-lumbar-disc-herniation-following-classical-surgery-laminotomy-with-discectomy
#1
Augustine Balaara, Xiao-Feng Xu, Young-Hui Huang, Li Dapeng
BACKGROUND: Several surgical variables and patient characteristics play an influential role in the prognosis of lumbar disc herniation following laminotomy with discectomy. This paper seeks to evaluate the perioperative predictor variables for the outcome of lumbar disc herniation. PATIENTS AND METHODS: From October 2013 to July 2016, 166 surgical patients were evaluated using prospectively collected data. Patients' preoperative independent variables (age, sex, body mass index, level of disc herniation, pain duration, and American Society of Anesthesiologists Physical Score) were correlated with functional outcome measures such as primary outcome measures (length of hospital stay; postoperative visual analog scale, VAS; Oswestry disability index, ODI) and secondary outcome measures (operation room time; estimated intraoperative blood loss, EBL; complications; readmission) as dependent variables...
February 21, 2017: Der Orthopäde
https://www.readbyqxmd.com/read/28223688/sequence-variant-at-8q24-21-associates-with-sciatica-caused-by-lumbar-disc-herniation
#2
Gyda Bjornsdottir, Stefania Benonisdottir, Gardar Sveinbjornsson, Unnur Styrkarsdottir, Gudmar Thorleifsson, G Bragi Walters, Aron Bjornsson, Ingvar H Olafsson, Elfar Ulfarsson, Arnor Vikingsson, Ragnheidur Hansdottir, Karl O Karlsson, Thorunn Rafnar, Ingileif Jonsdottir, Michael L Frigge, Augustine Kong, Asmundur Oddsson, Gisli Masson, Olafur T Magnusson, Tomas Gudbjartsson, Hreinn Stefansson, Patrick Sulem, Daniel Gudbjartsson, Unnur Thorsteinsdottir, Thorgeir E Thorgeirsson, Kari Stefansson
Lumbar disc herniation (LDH) is common and often debilitating. Microdiscectomy of herniated lumbar discs (LDHsurg) is performed on the most severe cases to resolve the resulting sciatica. Here we perform a genome-wide association study on 4,748 LDHsurg cases and 282,590 population controls and discover 37 highly correlated markers associating with LDHsurg at 8q24.21 (between CCDC26 and GSDMC), represented by rs6651255[C] (OR=0.81; P=5.6 × 10(-12)) with a stronger effect among younger patients than older. As rs6651255[C] also associates with height, we performed a Mendelian randomization analysis using height polygenic risk scores as instruments to estimate the effect of height on LDHsurg risk, and found that the marker's association with LDHsurg is much greater than predicted by its effect on height...
February 22, 2017: Nature Communications
https://www.readbyqxmd.com/read/28216749/percutaneous-endoscopic-lumbar-discectomy-results-of-first-100-cases
#3
Kanthila Mahesha
BACKGROUND: Lumbar disc herniation is a major cause of back pain and sciatica. The surgical management of lumbar disc prolapse has evolved from exploratory laminectomy to percutaneous endoscopic discectomy. Percutaneous endoscopic discectomy is the least invasive procedure for lumbar disc prolapse. The aim of this study was to analyze the clinical outcome, quality of life, neurologic function, and complications. MATERIALS AND METHODS: One hundred patients with lumbar disc prolapse who were treated with percutaneous endoscopic discectomy from May 2012 to January 2014 were included in this retrospective study...
January 2017: Indian Journal of Orthopaedics
https://www.readbyqxmd.com/read/28216287/association-between-measures-of-vertebral-endplate-morphology-and-lumbar-intervertebral-disc-degeneration
#4
Semra Duran, Mehtap Cavusoglu, Hatice Gul Hatipoglu, Deniz Sozmen Cılız, Bulent Sakman
PURPOSE: The aim of this study was to evaluate the association between vertebral endplate morphology and the degree of lumbar intervertebral disc degeneration via magnetic resonance imaging (MRI). METHODS: In total, 150 patients who met the inclusion criteria and were 20-60 years of age were retrospectively evaluated. Patients were evaluated for the presence of intervertebral disc degeneration or herniation, and the degree of degeneration was assessed at all lumbar levels...
February 16, 2017: Canadian Association of Radiologists Journal, Journal L'Association Canadienne des Radiologistes
https://www.readbyqxmd.com/read/28216208/a-rare-case-of-pediatric-lumbar-spinal-ependymoma-mimicking-meningitis
#5
Ezeali Mike Ekuma, Kiyoshi Ito, Akihiro Chiba, Yosuke Hara, Kohei Kanaya, Tetsuyoshi Horiuchi, Samuel Ohaegbulam, Kazuhiro Hongo
Spontaneous acute subarachnoid hemorrhage (SAH) from lumbar ependymoma in children is rare. We report a case of a14-year-old boy who developed sudden radicular low back pain while playing baseball. He was initially managed conservatively in a local hospital for suspected lumbar disc herniation, but later developed meningeal symptoms and fever before being referred to our hospital. There he underwent a diagnostic lumbar puncture in the emergency room; his cerebrospinal fluid suggested an SAH. Physical examination showed meningeal signs and cauda equina features...
February 12, 2017: World Neurosurgery
https://www.readbyqxmd.com/read/28214086/a-retrospective-study-of-epidural-and-intravenous-steroids-after-percutaneous-endoscopic-lumbar-discectomy-for-large-lumbar-disc-herniation
#6
Yang Zhang, Xin-Jian Yang, Teng-Hui Zeng, Yi-Yan Qiu, Yi-Tian Wang, Fei-Guo Liang
OBJECTIVE: To assess the early curative effect of epidural or intravenous administration of steroids during a percutaneous endoscopic lumbar discectomy (PELD). METHODS: 28 consecutive patients who underwent PELD due to large lumbar disc herniation between November 2014 and January 2016 were followed up for 6 months. These patients were divided into two groups according to the treatment they received after PELD. 14 patients (Group A) were treated by PELD and epidural steroids, while the other 14 patients (Group B) were treated by PELD and intravenous steroids...
January 20, 2017: Chinese Journal of Traumatology, Zhonghua Chuang Shang za Zhi
https://www.readbyqxmd.com/read/28203471/lumbar-scoliosis-combined-lumbar-spinal-stenosis-and-herniation-diagnosed-patient-was-treated-with-u-route-transforaminal-percutaneous-endoscopic-lumbar-discectomy
#7
Binbin Wu, Shaobo Zhang, Qingquan Lian, Haibo Yan, Xianfa Lin, Gonghao Zhan
The objective was to report a case of a 63-year-old man with a history of low back pain (LBP) and left leg pain for 2 years, and the symptom became more serious in the past 5 months. The patient was diagnosed with lumbar scoliosis combined with lumbar spinal stenosis (LSS) and lumbar disc herniation (LDH) at the level of L4-5 that was confirmed using Computerized Topography and Magnetic Resonance Imaging. The surgical team preformed a novel technique, "U" route transforaminal percutaneous endoscopic lumbar discectomy (PELD), which led to substantial, long-term success in reduction of pain intensity and disability...
2017: Case Reports in Orthopedics
https://www.readbyqxmd.com/read/28198779/genetic-variant-of-gpr126-gene-is-functionally-associated-with-adolescent-idiopathic-scoliosis-in-chinese-population
#8
Xiaodong Qin, Leilei Xu, Chao Xia, Weiguo Zhu, Weixiang Sun, Zhen Liu, Yong Qiu, Zezhang Zhu
STUDY DESIGN: A genetic association study of GPR126 gene with adolescent idiopathic scoliosis (AIS) in the Chinese population. OBJECTIVE: To investigate whether rs9403380, rs6570507 and rs7774095 of GPR126 gene are susceptible locus of AIS and to further determine the functional variants regulating gene expression in tissues of AIS. SUMMARY OF BACKGROUND DATA: Previous studies have identified several new susceptibility locus for AIS in GPR126 gene...
February 14, 2017: Spine
https://www.readbyqxmd.com/read/28191383/minimally-invasive-direct-lateral-interbody-fusion-mis-dlif-proof-of-concept-and-perioperative-results
#9
Hamid Abbasi, Ali Abbasi
BACKGROUND: Minimally invasive direct lateral interbody fusion (MIS-DLIF) is a novel approach for fusions of the lumbar spine. In this proof of concept study, we describe the surgical technique and report our experience and the perioperative outcomes of the first nine patients who underwent this procedure. STUDY DESIGN/SETTING: In this study we establish the safety and efficacy of this approach. MIS-DLIF was performed on 15 spinal levels in nine patients who failed to respond to conservative therapy for the treatment of a re-herniated disk, spondylolisthesis, or other severe disk disease of the lumbar spine...
January 14, 2017: Curēus
https://www.readbyqxmd.com/read/28180980/myofibroblast-in-the-ligamentum-flavum-hypertrophic-activity
#10
Junseok W Hur, Taegeun Bae, Sunghyeok Ye, Joo-Hyun Kim, Sunhye Lee, Kyoungmi Kim, Seung-Hwan Lee, Jin-Soo Kim, Jang-Bo Lee, Tai-Hyoung Cho, Jung-Yul Park, Junho K Hur
PURPOSE: Majority of the previous studies compared lumbar spinal stenosis (LSS) and lumbar disc herniation (LDH) patients for analyses of LFH. However, the separation of normal/hypertrophied LF has often been ambiguous and the severity of hypertrophic activity differed. Here, we present a novel analysis scheme for LFH in which myofibroblast is proposed as a major etiological factor for LFH study. METHODS: Seventy-one LF patient tissue samples were used for this study...
February 8, 2017: European Spine Journal
https://www.readbyqxmd.com/read/28178992/percutaneous-transforaminal-endoscopic-surgery-ptes-for-symptomatic-lumbar-disc-herniation-a-surgical-technique-outcome-and-complications-in-209-consecutive-cases
#11
Yu-Tong Gu, Zhan Cui, Hong-Wei Shao, Yun Ye, Ai-Qun Gu
BACKGROUND: We designed an easy posterolateral transforaminal endoscopic decompression technique, termed PTES, for radiculopathy secondary to lumbar disc herniation. The purpose of the study is to describe the technique of PTES and evaluate the efficacy and safety for treatment of lumbar disc herniation including primary herniation, reherniation, intracanal herniation, and extracanal herniation and to report outcome and complications. METHODS: PTES was performed to treat 209 cases of intracanal or extracanal herniations with or without extruding or sequestrated fragment, high iliac crest, scoliosis, calcification, or cauda equina syndrome including recurrent herniation after previous surgical intervention at the index level or adjacent disc herniation after decompression and fusion...
February 8, 2017: Journal of Orthopaedic Surgery and Research
https://www.readbyqxmd.com/read/28168345/association-between-pain-sensitivity-in-the-hand-and-outcomes-after-surgery-in-patients-with-lumbar-disc-herniation-or-spinal-stenosis
#12
Yvonne Lindbäck, Hans Tropp, Paul Enthoven, Björn Gerdle, Allan Abbott, Birgitta Öberg
PURPOSE: To investigate the association between pain sensitivity in the hand pre-surgery, and patient-reported outcomes (PROs) in function, pain and health pre- and post-surgery in patients with disc herniation or spinal stenosis. METHODS: This is a prospective cohort study with 82 patients. Associations between pressure-, cold- and heat pain threshold (PPT, CPT, HPT) in the hand pre-surgery and Oswestry, VAS pain, EQ-5D, HADS, and Self-Efficacy Scale, pre- and three months post-surgery; were investigated with linear regression...
February 6, 2017: European Spine Journal
https://www.readbyqxmd.com/read/28168343/is-infection-the-possible-initiator-of-disc-disease-an-insight-from-proteomic-analysis
#13
S Rajasekaran, Chitraa Tangavel, Siddharth N Aiyer, Sharon Miracle Nayagam, M Raveendran, Naveen Luke Demonte, Pramela Subbaiah, Rishi Kanna, Ajoy Prasad Shetty, K Dharmalingam
STUDY DESIGN: Proteomic and 16S rDNA analysis of disc tissues obtained in vivo. OBJECTIVE: To address the controversy of infection as an aetiology for disc disorders through protein profiling. There is raging controversy over the presence of bacteria in human lumbar discs in vivo, and if they represent contamination or infection. Proteomics can provide valuable insight by identifying proteins signifying bacterial presence and, also host defence response proteins (HDRPs), which will confirm infection...
February 6, 2017: European Spine Journal
https://www.readbyqxmd.com/read/28163949/anterior-to-posterior-migration-of-a-lumbar-disc-sequestration-surgical-remarks-and-technical-notes-about-a-tailored-microsurgical-discectomy
#14
Alessandro Frati, Alessandro Pesce, Mauro Palmieri, Tommaso Vangelista, Riccardo Caruso, Maurizio Salvati, Antonino Raco
Extrusion of disc material within the spinal canal complicates up to 28.6% of lumbar disc herniations. Due to the anatomical "corridors" created by the anterior midline septum and lateral membranes, relocation occurs with an anterior and anterolateral axial topography. Posterior migration is an extremely rare condition and anterior-to-posterior circumferential migration is an even rarer condition. Its radiological feature can be enigmatic and since, in more than 50% of cases, clinical onset is a hyperacute cauda equina syndrome, it may imply a difficult surgical decision in emergency settings...
2017: Case Reports in Surgery
https://www.readbyqxmd.com/read/28158159/full-endoscopic-assisted-lumbar-decompressive-surgery-performed-in-an-outpatient-ambulatory-facility-report-of-5-years-of-complications-and-risk-factors
#15
Solomon Kamson, Andrea M Trescot, Paul D Sampson, Yiyi Zhang
BACKGROUND: Minimally invasive surgery (MIS) technique is becoming the standard tissue sparing approach for decompression of lumbar central and lateral recess stenosis, intervertebral disc herniation, or any situation that would have required extensive open decompression laminectomy. Full-endoscopic or arthroscopic assisted surgery is arguably the "ultra-MIS" approach to lumbar spinal pathology. Age and body mass index (BMI) are significant risk factors to be considered in full-endoscopic assisted ultra-MIS...
February 2017: Pain Physician
https://www.readbyqxmd.com/read/28155820/analysis-of-reasons-for-failure-of-surgery-for-degenerative-disease-of-lumbar-spine
#16
Alicja Baranowska, Joanna Baranowska, Paweł Baranowski
BACKGROUND: In the aging society, there is a growing number of patients with advanced degenerative disease of the spine. These patients frequently require surgical treatment. This paper aims to analyse the reasons for failure of surgery for degenerative disease of the lumbar spine. MATERIAL AND METHODS: Histories of patients operated on by one group of surgeons in the Neuroorthopaedic Department of "STOCER" in 2014 and 2015 due to degenerative disease of the lumbar spine were analysed retrospectively...
March 23, 2016: Ortopedia, Traumatologia, Rehabilitacja
https://www.readbyqxmd.com/read/28149141/are-transitional-vertebra-and-spina-bifida-occulta-related-with-lumbar-disc-herniation-and-clinical-parameters-in-young-patients-with-chronic-low-back-pain
#17
Emine Eda Kurt, Aysegul Kuçukali Turkyilmaz, Yeliz Dadali, Hatice Rana Erdem, Figen Tuncay
OBJECTIVE: Lumbosacral transitional vertebra (LSTV) and spina bifida occulta (SBO) are widespread within the lumbosacral spine. Their connection to lumbar disc herniation (LDH) and/or lower back pain has been debated in the current literature; however, there is no consensus. The purpose of this study is to evaluate the relationship between the frequency of LSTV and SBO with that of LDH among young patients with chronic lower back pain. STUDY DESIGN: Cross-sectional...
October 2016: Eurasian Journal of Medicine
https://www.readbyqxmd.com/read/28137544/contralateral-approach-for-minimally-invasive-treatment-of-upper-lumbar-intervertebral-disc-herniation-technical-note-and-case-series
#18
Ribhu T Jha, Hasan R Syed, Michael Catalino, Faheem A Sandhu
BACKGROUND: Upper lumbar disc herniations comprise only 1 to 2% of all lumbar disc herniations. Patients present with non-specific signs and symptoms in comparison to predictable radiculopathies as seen in lower lumbar disc herniations. The unique anatomical characteristics of the upper lumbar spine present several challenges for safe and effective surgical treatment of disc herniations. The authors review the anatomy of the upper lumbar spine, describe a novel approach to upper lumbar disc herniations, and present three cases with a focus on clinical outcome and technical pearls...
January 27, 2017: World Neurosurgery
https://www.readbyqxmd.com/read/28132923/anatomical-assessment-of-variations-in-kambin-s-triangle-a-surgical-and-cadaver-study
#19
Ali Fahir Ozer, Tuncer Suzer, Halil Can, Mani Falsafi, Murat Aydin, Mehdi Sasani, Tunc Oktenoglu
BACKGROUND: The relationship of exiting root and Kambin's triangle is discussed in this article. OBJECTIVE: Transforaminal endoscopic surgery as the gold standard of less invasive lumbar disc surgeries is performed through Kambin's triangle. Existing root damage is one of the most important complication for this type of surgery. Anatomical variations in Kambin's triangle may be the main reason for nerve root damage during endoscopic lumbar disc surgery. METHOD: Kambin's triangle was investigated with surgical views and cadaver studies...
January 26, 2017: World Neurosurgery
https://www.readbyqxmd.com/read/28131733/spinal-cord-ischemia-in-scheuermann-disease-a-report-of-three-cases
#20
Léa Chiche, Robert-Yves Carlier, Dan Siahou, Arnaud Nataf, Caroline Hugeron, Clémence Palazzo
BACKGROUND: Neurological complications in Scheuermann's disease are rare but serious. CASE REPORTS: We report three cases of severe neurological deficit due to medullar ischemia attributable to the compression of a radiculomedullar artery by thoracic (two cases) and lumbar (one case) disc herniations associated with Scheuermann's disease. They were not treated surgically because of the absence of direct spinal cord compression or definitive spinal cord ischemia...
January 25, 2017: Joint, Bone, Spine: Revue du Rhumatisme
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