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Lumbar disc herniation

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https://www.readbyqxmd.com/read/28342919/radiation-exposure-to-the-surgeon-during-ultrasound-assisted-transforaminal-percutaneous-endoscopic-lumbar-discectomy-a-prospective-study
#1
Ruihui Wu, Xuqiang Liao, Hong Xia
PURPOSE: To determine the radiation dose to the surgeon during ultrasound-assisted transforaminal percutaneous endoscopic lumbar discectomy (transforaminal PELD) for lumbar disc herniation, and investigate whether the usage of ultrasonography could reduce the radiation exposure to surgeon. METHODS: The stages of needle insertion and foraminal plasty for transforaminal PELD were performed under ultrasound guidance and confirmed by fluoroscopy according to the standard technique by two spinal surgeons separately in 25 transforaminal PELDs (25 levels)...
March 22, 2017: World Neurosurgery
https://www.readbyqxmd.com/read/28339442/clinical-outcome-of-full-endoscopic-interlaminar-discectomy-for-single-level-lumbar-disc-herniation-a-minimum-of-5-year-follow-up
#2
Zhiming Tu, Ya Wei Li, Bing Wang, Guohua Lu, Lei Li, Lei Kuang, Yuliang Dai
BACKGROUND: Full-endoscopic interlaminar discectomy (FEID) is widely applied for the treatment of lumbar disc herniation (LDH) and satisfactory short-term outcomes have been achieved. However, the long-term evaluation for this technique is still lacking, especially the comparison between FEID and microendoscopic discectomy (MED). OBJECTIVE: To evaluate the clinical outcome of FEID technique in comparison with MED for single-level LDH with a minimum of 5-year follow-up...
March 2017: Pain Physician
https://www.readbyqxmd.com/read/28339437/complications-of-lumbar-disc-herniation-following-full-endoscopic-interlaminar-lumbar-discectomy-a-large-single-center-retrospective-study
#3
Tian-Hang Xie, Jian-Cheng Zeng, Zhu-Hai Li, Liang Wang, Hong-Fei Nie, Hu-Shan Jiang, Yue-Ming Song, Qing-Quan Kong
BACKGROUND: The new surgical procedure of full-endoscopic interlaminar lumbar discectomy (FILD) has achieved favorable effects in the treatment of lumbar disc herniation (LDH). Along with the wide range of applications of FILD, a series of complications related to the operation has gradually emerged. OBJECTIVE: To describe the types, incidences, and characteristics of complications following FILD and to explore preventative and treatment measures. STUDY DESIGN: Retrospective, observational study...
March 2017: Pain Physician
https://www.readbyqxmd.com/read/28338454/impact-of-preoperative-diagnosis-on-patient-satisfaction-following-lumbar-spine-surgery
#4
Charles H Crawford, Leah Y Carreon, Mohamad Bydon, Anthony L Asher, Steven D Glassman
OBJECTIVE Patient satisfaction is a commonly used metric in the current health care environment. While factors that affect patient satisfaction following spine surgery are complex, the authors of this study hypothesized that specific diagnostic groups of patients are more likely to be satisfied after spine surgery and that this is reflected in patient-reported outcome measures. The purpose of this study was to determine if the preoperative diagnosis-disc herniation, stenosis, spondylolisthesis, adjacent segment degeneration, or mechanical disc collapse-would impact patient satisfaction following surgery...
March 24, 2017: Journal of Neurosurgery. Spine
https://www.readbyqxmd.com/read/28336484/lumbar-mri-findings-in-patients-with-and-without-waddell-signs
#5
J S Cox, S Blizzard, H Carlson, J Hiratza, J U Yoo
BACKGROUND CONTEXT: Waddell Signs (WS), introduced as a method to establish patients with substantial psychosocial components to their low back pain, carry a negative association despite no literature evaluating whether physical disease is associated with them. PURPOSE: To compare lumbar MRI findings between the patients with and without Waddell's Signs. STUDY DESIGN: Retrospective cohort study based on prospectively collected data PATIENT SAMPLE: Thirty patients aged 35-55 with an ODI score >50 randomly selected such that there was an even distribution of patients based on number of WS OUTCOME MEASURES: ODI and SF-12 scores, number of WS, presence and severity of spinal pathology METHODS: MRIs were reviewed by three spine specialists blinded to clinical exam findings, number of WS, and patient identity...
March 20, 2017: Spine Journal: Official Journal of the North American Spine Society
https://www.readbyqxmd.com/read/28336482/surgical-treatment-of-lumbar-disc-herniation-in-different-ages-evaluation-of-11-237-patients
#6
Fredrik Strömqvist, Björn Strömqvist, Bo Jönsson, Magnus K Karlsson
BACKGROUND CONTEXT: Surgical treatment of lumbar disc herniation (LDH) may lead to different outcome in young, middle aged and elderly. However, no study has by the same data ascertainment evaluated referral pattern, improvement and outcome in different age strata. PURPOSE: To evaluate referral pattern and outcome in patients surgically treated due to LDH in different ages. STUDY DESIGN: Register study of prospectively collected data. PATIENT SAMPLE: In SweSpine, the national Swedish register for spinal surgery, we identified 11...
March 20, 2017: Spine Journal: Official Journal of the North American Spine Society
https://www.readbyqxmd.com/read/28331979/clinical-and-radiological-factors-related-to-the-presence-of-motor-deficit-in-lumbar-disc-prolapse-a-prospective-analysis-of-70-consecutive-cases-with-neurological-deficit
#7
Vibhu Krishnan, Shanmuganathan Rajasekaran, Siddharth N Aiyer, Rishi Kanna, Ajoy Prasad Shetty
PURPOSE: To analyse the clinic-radiological factors associated with neurological deficit following lumbar disc herniation. METHODS: A prospective, cross-sectional study was performed in 140 cases of micro-discectomy following lumbar disc herniation. Group 1 included 70 consecutive patients with motor deficit and group 2 (controls) included 70 patients with intact neurology. Motor deficit was defined as the occurrence of motor power ≤3/5 in L2-S1 myotomes. Multiple clinical and radiological parameters were studied between the two groups...
March 22, 2017: European Spine Journal
https://www.readbyqxmd.com/read/28331218/identification-of-a-novel-heterozygous-mutation-of-the-aggrecan-gene-in-a-family-with-idiopathic-short-stature-and-multiple-intervertebral-disc-herniation
#8
Sumito Dateki, Akiko Nakatomi, Satoshi Watanabe, Hitomi Shimizu, Yukiko Inoue, Hideo Baba, Koh-Ichiro Yoshiura, Hiroyuki Moriuchi
Aggrecan is a critical proteoglycan component of the extracellular matrix of the growth plates and articular cartilage and has a key role in the biophysical and biomechanical properties of cartilage. Recently, heterozygous mutations in the ACAN gene, which encodes aggrecan, have been identified in patients with short stature and accelerated bone age. We herein report another family with a heterozygous ACAN mutation associated with idiopathic short stature along with accelerated bone age and early-onset herniation of the lumbar discs at the levels of L1/2 through L5/S1...
March 23, 2017: Journal of Human Genetics
https://www.readbyqxmd.com/read/28298159/biological-behavior-of-human-nucleus-pulposus-mesenchymal-stem-cells-in-response-to-changes-in-the-acidic-environment-during-intervertebral-disc-degeneration
#9
Jianjun Liu, Hui Tao, Cailiang Shen, Xiaoying Liu, Hanbang Wang, Fulong Dong, Renjie Zhang, Jie Li, Peng Ge, Peiwen Song, Huaqing Zhang, Peng Xu
An acidic environment is vital for the maintenance of cellular activities but can be affected tremendously during intervertebral disc degeneration. The effect of changes in the acidity of the environment on human nucleus pulposus mesenchymal stem cells (NP-MSCs) is unknown, however. Thus, this study aimed to observe the biological effects of acidic conditions mimicking a degenerated intervertebral disc on NP-MSCs in vitro. NP-MSCs were isolated from patients with lumbar disc herniation and were further identified by their immunophenotypes and multilineage differentiation...
March 16, 2017: Stem Cells and Development
https://www.readbyqxmd.com/read/28296365/-clinical-and-radiological-results-of-non-fusion-by-static-interspinous-spacer
#10
Juan Enrique Guzmán-Carranza, Amado González-Moga, Leonardo Álvarez-Vázquez, Gabriel Huerta-Hernández, Abraham Isáis-Gómez, Víctor Galicia-Luna, Víctor Hugo Anaya-Contreras
BACKGROUND: The aim of this paper is to demonstrate the clinical and radiological results of non-fusion in patients with degenerative disc disease and lumbar by placing static interspinous spacer. METHODS: A retrospective study was made in the period between January 2010 and January 2013, 130 patients were treated by placing static interspinous spacer. Patients were divided into: Group 1 (treated for diagnosis of degenerative lumbar spinal stenosis), and group 2 (those diagnosed with lumbar disc herniation)...
March 2017: Revista Médica del Instituto Mexicano del Seguro Social
https://www.readbyqxmd.com/read/28294192/microstructural-changes-are-coincident-with-the-improvement-of-clinical-symptoms-in-surgically-treated-compressed-nerve-roots
#11
Weifei Wu, Jie Liang, Ying Chen, Aihua Chen, Yongde Wu, Zong Yang
Diffusion tensor imaging (DTI) has been widely used to visualize peripheral nerves, but the microstructure of compressed nerve roots can be assessed using DTI. However, there are no data regarding the association among microstructural changes evaluated using DTI, the symptoms assessed using the Oswestry Disability Index (ODI) and the duration of symptoms after surgery in patients with lumbar disc herniation (LDH). Thirty patients with unilateral radiculopathy were investigated using DTI. The changes in the mean fractional anisotropy (FA) and the apparent diffusion coefficient (ADC) values as well as the correlation between these changes and the severity and duration of the clinical symptoms were investigated before and at least one month after surgery...
March 15, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28283839/selective-phosphodiesterase-2a-inhibitor-alleviates-radicular-inflammation-and-mechanical-allodynia-in-non-compressive-lumbar-disc-herniation-rats
#12
Jun-Nan Wang, Xue-Jun Zhao, Zhi-Hua Liu, Xu-Li Zhao, Tao Sun, Zhi-Jian Fu
PURPOSE: Phosphodiesterase inhibitors possess anti-inflammatory properties. In addition, some studies report that phosphodiesterase 2A (PDE2A) are highly expressed in the dorsal horn of the spinal cord. The present study aimed to investigate whether intrathecal administration of Bay 60-7550, a specific PDE2A inhibitor, could alleviate mechanical allodynia in non-compressive lumbar disc herniation (NCLDH) rats. METHODS: Rat NCLDH models by autologous nucleus pulposus implantation to dorsal root ganglion were established...
March 10, 2017: European Spine Journal
https://www.readbyqxmd.com/read/28277385/transforaminal-lumbar-interbody-fusion-versus-mini-open-anterior-lumbar-interbody-fusion-with-oblique-self-anchored-stand-alone-cages-for-the-treatment-of-lumbar-disc-herniation-a-retrospective-study-with-2-year-follow-up
#13
Guohua Lü, Lei Kuang, Bing Wang
STUDY DESIGN: Retrospective study OBJECTIVE.: To evaluate the clinical and radiological outcomes of mini-open ALIF (MO-ALIF) with self-anchored stand alone cages for the treatment of lumbar disc herniation in comparison with transforaminal lumbar interbody fusion (TLIF). SUMMARY OF BACKGROUND DATA: Currently, whether ALIF is superior to TLIF for the treatment of lumbar disc herniation remains controversial. METHODS: This study retrospectively reviewed 82 patients who underwent MO-ALIF with self-anchored standalone cages (n = 42) or TLIF (n = 40) for the treatment of lumbar disc herniation between April 2013 and October 2014...
March 8, 2017: Spine
https://www.readbyqxmd.com/read/28267905/-results-of-percutaneous-discectomy-in-the-management-of-lumbar-disc-herniation
#14
P G Lima-Ramírez, A J Montiel-Jarquín, R G Barragán-Hervella, M A Sánchez-Durán, A Ochoa-Neri, J Loria-Castellanos, C Vázquez-Rodríguez, A Villatoro-Martínez, J J Castillo-Pérez
INTRODUCTION: Percutaneous discectomy is a disc decompression technique approved by the FDA that is useful to improve pain caused by a herniated disc. However, its practice is under discussion because the benefits of the technique are controversial. OBJECTIVES: To describe the clinical course of patients with low lumbar disc herniation (L4-L5, L5-S1) treated by percutaneous surgery within one year of surgery and prove that it is a useful surgical option for the relief of symptoms caused by this pathological entity...
July 2016: Acta Ortopédica Mexicana
https://www.readbyqxmd.com/read/28264243/lumbar-disc-herniation-presented-with-contralateral-symptoms
#15
Pius Kim, Chang Il Ju, Hyeun Sung Kim, Seok Won Kim
OBJECTIVE: This study aimed to unravel the putative mechanism underlying the neurologic deficits contralateral to the side with lumbar disc herniation (LDH) and to elucidate the treatment for this condition. METHODS: From January 2009 to June 2015, 8 patients with LDH with predominantly contralateral neurologic deficits underwent surgical treatment on the side with LDH with or without decompressing the symptomatic side. A retrospective review of charts and radiological records of these 8 patients was performed...
March 2017: Journal of Korean Neurosurgical Society
https://www.readbyqxmd.com/read/28261430/assessment-of-anteroposterior-subpedicular-approach-and-oblique-scotty-dog-subpedicular-approach-for-selective-nerve-root-block
#16
Arun-Kumar Kaliya-Perumal, Yu-Cheng Yeh, Chi-An Luo, Kit-Yang Joey-Tan
BACKGROUND: The technique used to administer a selective nerve root block (SNRB) varies depending on individual expertise. Both the anteroposterior (AP) subpedicular approach and oblique Scotty dog subpedicular approach are widely practiced. However, the literature does not provide a clear consensus regarding which approach is more suitable. Hence, we decided to analyse the procedural parameters and clinical outcomes following SNRBs using these two approaches. METHODS: Patients diagnosed with a single lumbar herniated intervertebral disc (HIVD) refractory to conservative management but not willing for immediate surgery were selected for a prospective nonrandomized comparative study...
March 2017: Clinics in Orthopedic Surgery
https://www.readbyqxmd.com/read/28260009/molecular-profile-of-major-growth-factors-in-lumbar-intervertebral-disc-herniation-correlation-with-patient-clinical-and-epidemiological-characteristics
#17
Alexandros Tsarouhas, Giannoula Soufla, Konstantinos Tsarouhas, Pavlos Katonis, Dritan Pasku, Antonis Vakis, Aristides M Tsatsakis, Demetrios A Spandidos
The involvement of growth factors (GFs) in the pathogenesis of lumbar intervertebral disc (ID) herniation and the spontaneous resorption of herniated ID fragments remains only partially elucidated. A simultaneous assessment of the transcript levels of numerous GFs and their association with clinical and epidemiological profiles of human ID herniation would provide valuable insight into the biology and clinical course of the disease. In the present study, we examined simultaneously the transcript levels of vascular endothelial growth factor (VEGF), transforming growth factor β1 (TGF‑β1), basic fibroblast growth factor 2 (bFGF2), platelet derived growth factor (PDGF) isoforms and receptors, epidermal growth factor (EGF) and insulin growth factor‑1 (IGF‑1) in herniated and control ID specimens and investigated their correlation with the clinicopathological profiles of patients suffering from symptomatic lumbar ID herniation...
February 20, 2017: Molecular Medicine Reports
https://www.readbyqxmd.com/read/28257294/the-1-year-results-of-lumbar-transforaminal-epidural-steroid-injection-in-patients-with-chronic-unilateral-radicular-pain-the-relation-to-mri-findings-and-clinical-features
#18
Harald Ekedahl, Bo Jönsson, Mårten Annertz, Richard B Frobell
OBJECTIVE: In patients with chronic radicular pain, we aimed to evaluate subgroup differences in 1-yr response to transforaminal epidural steroid injection. DESIGN: In this longitudinal cohort study of 100 subjects, 170 transforaminal epidural steroid injections were performed for 1 yr. The sample was stratified by type of disc herniation (protrusion n = 57, extrusion n = 27), by location of disc herniation (central/subarticular n = 60, foraminal n = 24), by grade of nerve root compression (low-grade compression n = 61, high-grade subarticular nerve compression n = 14, high-grade foraminal nerve compression n = 25), and by positive Slump test (n = 67)...
March 2, 2017: American Journal of Physical Medicine & Rehabilitation
https://www.readbyqxmd.com/read/28254514/the-prognostic-value-of-preoperative-participation-in-activities-of-daily-living-on-postoperative-outcomes-following-lumbar-discectomy
#19
Dana A Leonard, Andrew J Schoenfeld, Mitchel B Harris, Christopher M Bono
OBJECTIVES: In other surgical fields, preoperative level of participation in activities of daily living (ADLs) has been found to be important in predicting outcomes. To date, postoperative ADL measurements have only been used to characterize outcomes following lumbar discectomy. The present study's goal was to determine if patients' preoperative ability to perform ADLs correlates with their postoperative outcomes after lumbar discectomy at 3 months and 1 year. PATIENTS AND METHODS: This retrospective study was performed using prospectively collected data from patients prospectively enrolled in a randomized clinical trial...
February 20, 2017: Clinical Neurology and Neurosurgery
https://www.readbyqxmd.com/read/28253483/factors-that-influence-recurrent-lumbar-disc-herniation
#20
M E Yaman, A Kazancı, N D Yaman, F Baş, G Ayberk
INTRODUCTION: The most common cause of poor outcome following lumbar disc surgery is recurrent herniation. Recurrence has been noted in 5% to 15% of patients with surgically treated primary lumbar disc herniation. There have been many studies designed to determine the risk factors for recurrent lumbar disc herniation. In this study, we retrospectively analysed the influence of disc degeneration, endplate changes, surgical technique, and patient's clinical characteristics on recurrent lumbar disc herniation...
March 3, 2017: Hong Kong Medical Journal, Xianggang Yi Xue za Zhi
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