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Lumbar disc herniation

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https://www.readbyqxmd.com/read/29329586/il-33-st2-signaling-contributes-to-radicular-pain-by-modulating-mapk-and-nf-%C3%AE%C2%BAb-activation-and-inflammatory-mediator-expression-in-the-spinal-cord-in-rat-models-of-noncompressive-lumber-disk-herniation
#1
Si-Jian Huang, Jian-Qin Yan, Hui Luo, Lu-Yao Zhou, Jian-Gang Luo
BACKGROUND: Immune and inflammatory responses occurring in the spinal cord play a pivotal role in the progression of radicular pain caused by intervertebral disk herniation. Interleukin-33 (IL-33) orchestrates inflammatory responses in a wide range of inflammatory and autoimmune disorders of the nervous system. Thus, the purpose of this study is to investigate the expression of IL-33 and its receptor ST2 in the dorsal spinal cord and to elucidate whether the inhibition of spinal IL-33 expression significantly attenuates pain-related behaviors in rat models of noncompressive lumbar disc herniation...
January 12, 2018: Journal of Neuroinflammation
https://www.readbyqxmd.com/read/29325949/the-comparison-of-med-and-peld-in-the-treatment-of-adolescent-lumbar-disc-herniation-a-five-year-retrospective-follow-up
#2
Haiyin Li, Changqing Li, Changqing Jiang, Xuesong Mu, Weiren Lan, Yue Zhou
No abstract text is available yet for this article.
January 8, 2018: World Neurosurgery
https://www.readbyqxmd.com/read/29322267/association-of-decision-making-in-spinal-surgery-with-specialty-and-emotional-involvement-the-indications-in-spinal-surgery-indiana-survey
#3
Nico Sollmann, Carmen Morandell, Lucia Albers, Michael Behr, Alexander Preuss, Andreas Dinkel, Bernhard Meyer, Sandro M Krieg
BACKGROUND: Although recent trials provided level I evidence for the most common degenerative lumbar spinal disorders, treatment still varies widely. Thus, the Indications in Spinal Surgery (INDIANA) survey explores whether decision-making is influenced by specialty or personal emotional involvement of the treating specialist. METHOD: Nationwide, neurosurgeons and orthopedic surgeons specialized in spine surgery were asked to answer an Internet-based questionnaire with typical clinical patient cases of lumbar disc herniation (DH), lumbar spinal stenosis (SS), and lumbar degenerative spondylolisthesis (SL)...
January 10, 2018: Acta Neurochirurgica
https://www.readbyqxmd.com/read/29321948/performance-of-an-annular-closure-device-in-a-real-world-heterogeneous-at-risk-lumbar-discectomy-population
#4
Adisa Kuršumović, Stefan Rath
Study design/setting Retrospective analysis of single-center registry outcomes data. Objective Assess the utility of an annular closure device (ACD) as an adjunct to limited discectomy for lumbar disc herniation (LDH). Background Recurrent lumbar disc herniation (rLDH) following limited discectomy persists at clinically significant rates, especially in large annular defect (at least 6 mm width) patients. While the etiology of reherniation is often multifactorial, inadequate annular occlusion remains one of the foremost considerations...
November 6, 2017: Curēus
https://www.readbyqxmd.com/read/29321344/a-genetic-variant-in-col11a1-is-functionally-associated-with-lumbar-disc-herniation-in-chinese-population
#5
Wenjun Liu, Guisen Sun, Longsheng Guo, Lulu Wang, Weiqiang Fan, Minglei Lang, Dan Chen, Xinhao Yi
This study aimed to explore whether the genetic variant of COL11A1 is functionally associated with the development of lumbar disc herniation (LDH) in Chinese population. SNP rs1676486 of COL11A1 was genotyped in 647 patients and 532 healthy controls. The differences of genotype and allele distributions between LDH patients and healthy controls were evaluated using the χ² test. One-way ANOVA test was used to compare the relationship between genotypes and clinical features including tissue expression of COL11A1 and the degree of disc degeneration...
December 2017: Journal of Genetics
https://www.readbyqxmd.com/read/29315127/tidemark-avulsions-are-a-predominant-form-of-endplate-irregularity
#6
Britta Berg-Johansen, Deeptee Jain, Ellen C Liebenberg, Aaron J Fields, Thomas M Link, Conor W O'Neill, Jeffrey C Lotz
STUDY DESIGN: Descriptive histologic and MRI study of human cadaveric spines. OBJECTIVE: To identify and characterize common endplate pathologies to form a histologic foundation for an etiology-based classification system. SUMMARY OF BACKGROUND DATA: Irregularities at the spinal disc-vertebra interface are associated with back pain and intervertebral disc herniation injuries. However, there is currently a lack of consensus regarding terminology for classification...
January 8, 2018: Spine
https://www.readbyqxmd.com/read/29315122/should-patients-with-recurrent-lumbar-disc-herniations-be-fused
#7
Michael J Elsenbeck, Stephen Fernicola, Scott C Wagner
No abstract text is available yet for this article.
January 8, 2018: Clinical Spine Surgery
https://www.readbyqxmd.com/read/29312845/transforaminal-percutaneous-endoscopic-discectomy-using-transforaminal-endoscopic-spine-system-technique-pitfalls-that-a-beginner-should-avoid
#8
REVIEW
Stylianos Kapetanakis, Grigorios Gkasdaris, Antonios G Angoules, Panagiotis Givissis
Transforaminal Percutaneous Endoscopic Discectomy (TPED) is a minimally invasive technique mainly used for the treatment of lumbar disc herniation from a lateral approach. Performed under local anesthesia, TPED has been proven to be a safe and effective technique which has been also associated with shorter rehabilitation period, reduced blood loss, trauma, and scar tissue compared to conventional procedures. However, the procedure should be performed by a spine surgeon experienced in the specific technique and capable of recognizing or avoiding various challenging conditions...
December 18, 2017: World Journal of Orthopedics
https://www.readbyqxmd.com/read/29307767/epidural-fluid-collection-after-percutaneous-endoscopic-lumbar-discectomy
#9
Wei-Chiang Liu, Gun Choi, Sang-Ho Lee, Amy M Kwon, K Hwan Kim, Jeeyoung Park, Hyeon Seon Park
OBJECTIVE: The frequency and extent of epidural fluid collection after percutaneous endoscopic lumbar discectomy (PELD) have not been previously described. The purpose of this study was to evaluate the significance of epidural fluid collection after PELD. METHODS: From March 2008 to November 2015, immediate post-operative magnetic resonance (MR) images of 464 consecutive patients, comprising 284 men and 180 women, were obtained after PELD. The mean age of the patients at the time of admission was 43...
January 4, 2018: World Neurosurgery
https://www.readbyqxmd.com/read/29306376/sonography-guided-lumbar-nerve-and-facet-blocks-the-first-report-of-clinical-outcome-from-iran
#10
H Sadeghian, R Motiei-Langroudi
INTRODUCTION: Nerve root block (NRB) and facet block (FB) are viable options for pain arising from facet and lumbar disc herniation (LDH) not responding to conservative therapy but still not suitable for surgery. Classically, they are performed under fluoroscopy and computed tomography (CT) guidance, which have the disadvantages of radiation exposure and limited accessibility. The aim of this study was to assess the effectiveness of US guided FB and NRB in patients suffering from facet arthropathy and LDH...
February 2018: Radiography
https://www.readbyqxmd.com/read/29304802/evaluation-of-the-influence-of-kyphosis-and-scoliosis-on-intervertebral-disc-extrusion-in-french-bulldogs
#11
Maria Claudia C M Inglez de Souza, Richard Ryan, Gert Ter Haar, Rowena M A Packer, Holger A Volk, Steven De Decker
BACKGROUND: Although thoracic vertebral malformations with kyphosis and scoliosis are often considered incidental findings on diagnostic imaging studies of screw-tailed brachycephalic breeds, they have been suggested to interfere with spinal biomechanics and intervertebral disc degeneration. It is however unknown if an abnormal spinal curvature also predisposes dogs to develop clinically relevant intervertebral disc herniations. The aim of this study was to evaluate if the occurrence of thoracic vertebral malformations, kyphosis or scoliosis would be associated with a higher prevalence of cervical or thoracolumbar intervertebral disc extrusion in French bulldogs...
January 5, 2018: BMC Veterinary Research
https://www.readbyqxmd.com/read/29303471/comparison-of-percutaneous-endoscopic-transforaminal-discectomy-microendoscopic-discectomy-and-microdiscectomy-for-symptomatic-lumbar-disc-herniation-minimum-2-year-follow-up-results
#12
Xinyu Liu, Suomao Yuan, Yonghao Tian, Lianlei Wang, Liangtai Gong, Yanping Zheng, Jianmin Li
OBJECTIVE This study aimed to evaluate the clinical outcomes of percutaneous endoscopic transforaminal discectomy (PETD), microendoscopic discectomy (MED), and microdiscectomy (MD) for treatment of symptomatic lumbar disc herniation (LDH). METHODS One hundred ninety-two patients with symptomatic LDH at L3-4 and L4-5 were included in this study. The mean (± SD) age of patients was 34.2 ± 2.6 years (range 18-62 years). The patients were divided into groups as follows: group A was treated with PETD and included 60 patients (31 men and 29 women) with a mean age of 36...
January 5, 2018: Journal of Neurosurgery. Spine
https://www.readbyqxmd.com/read/29303469/percutaneous-transforaminal-endoscopic-discectomy-compared-with-microendoscopic-discectomy-for-lumbar-disc-herniation-1-year-results-of-an-ongoing-randomized-controlled-trial
#13
Zihao Chen, Liangming Zhang, Jianwen Dong, Peigen Xie, Bin Liu, Qiyou Wang, Ruiqiang Chen, Feng Feng, Bu Yang, Tao Shu, Shangfu Li, Yang Yang, Lei He, Mao Pang, Limin Rong
OBJECTIVE A prospective randomized controlled study was conducted to clarify whether percutaneous transforaminal endoscopic discectomy (PTED) results in better clinical outcomes and less surgical trauma than microendoscopic discectomy (MED). METHODS In this single-center, open-label, randomized controlled trial, patients were included if they had persistent signs and symptoms of radiculopathy with corresponding imaging-confirmed lumbar disc herniation. Patients were randomly allocated to the PTED or the MED group by computer-generated randomization codes...
January 5, 2018: Journal of Neurosurgery. Spine
https://www.readbyqxmd.com/read/29288395/morphometric-study-of-the-posterior-longitudinal-ligament-at-the-lumbar-spine
#14
Céline Salaud, Stéphane Ploteau, Olivier Hamel, Olivier Armstrong, Antoine Hamel
PURPOSE: There are only two descriptions of posterior longitudinal ligament (PLL) at the lumbar spine level but its morphologic characteristics are different to cervical and thoracic levels. METHOD: Spine explantation (from Th12 to L5) followed by resection of the neural arch and the dural sheath in 13 fresh cadavers was performed. The PLL was isolated from other epidural structures and its width was measured and compared to the vertebral body width at each vertebral levels...
December 29, 2017: Surgical and Radiologic Anatomy: SRA
https://www.readbyqxmd.com/read/29288379/a%C3%A2-new-radiographic-feature-of-lower-lumbar-disc-herniation-in-young-patients
#15
Shiwu Tao, Lin Jin, Zhiyong Hou, Wei Zhang, Tao Chen, Yingze Zhang
PURPOSE: In our study, we assessed the condition of the lumbar laminae defect of L5, other than the defect of spina bifida, in a group of different ages with lower lumbar disc herniation (LDH). We hypothesize that the laminae defect of L5 may be a radiographic feature in young patients with lower LDH. METHODS: We analyzed the features of the laminae of L5 from the anteroposterior X-rays of the lumbosacral spine in 342 patients suffering from lower LDH. The patients were divided into three groups depending on age: age <45 (group A), 45 ≤ age ≤ 59 (group B) and age>59 (group C)...
December 29, 2017: International Orthopaedics
https://www.readbyqxmd.com/read/29275382/intradural-lumbar-disc-herniation-detected-by-3d-ciss-mri
#16
Laurence Crivelli, Vincent Dunet
A 73-year-old man who presented with right lumbosciatic pain underwent a neurosurgical operation for a voluminous L2-L3 disc herniation, seen on conventional MRI images. No disc herniation was identified in the epidural space during the surgery. Just after the operation, the patient started to present pain in the left L3 territory and was not able to walk any more. A second MRI including three-dimensional (3D) high-resolution constructive interference in steady state (CISS) sequence showed that the voluminous L2-L3 disc split the posterior longitudinal ligament and the anterior dura mater, extended intradurally and compressed the cauda equina to the right...
December 22, 2017: BMJ Case Reports
https://www.readbyqxmd.com/read/29274599/bowel-obstruction-in-obturator-hernia-a-challenging-diagnosis
#17
L Conti, E Baldini, P Capelli, C Capelli
INTRODUCTION: The obturator hernia is a rare pelvic hernia that often comes in the shape of bowel obstruction caused by the presence of an intestinal segment, more often ileum, passing trough the obturator foramen of the pelvic wall (Fig. 1). This type of hernia accounts for 0.5-1.4% of all hernias. CASE PRESENTATION: We report the clinical case of a 84-year-old woman with no previous surgical interventions, who went to the emergency room complaining of vomit and nausea, bowels closed to gas and stool, which she had experienced for three previous days...
December 7, 2017: International Journal of Surgery Case Reports
https://www.readbyqxmd.com/read/29273659/pted-study-design-of-a-non-inferiority-randomised-controlled-trial-to-compare-the-effectiveness-and-cost-effectiveness-of-percutaneous-transforaminal-endoscopic-discectomy-pted-versus-open-microdiscectomy-for-patients-with-a-symptomatic-lumbar-disc-herniation
#18
Ankie Seiger, Pravesh S Gadjradj, Biswadjiet S Harhangi, Job Lc van Susante, Wilco C Peul, Maurits W van Tulder, Michiel R de Boer, Sidney M Rubinstein
INTRODUCTION: Lumbosacral radicular syndrome is often caused by a disc herniation. The standard surgical technique to remove a disc herniation is open microdiscectomy. An alternative technique is percutaneous transforaminal endoscopic discectomy (PTED), which is less invasive. In the Netherlands, PTED is not currently considered as standard care, and therefore not reimbursed within public health insurance. A pragmatic, multicentre, non-inferiority, randomised controlled trial has been designed to determine the effectiveness and cost-effectiveness of PTED versus open microdiscectomy for the treatment of lumbar disc herniation...
December 21, 2017: BMJ Open
https://www.readbyqxmd.com/read/29258942/early-postoperative-mri-findings-following-percutaneous-endoscopic-lumbar-discectomy-and-their-correlations-with-clinical-outcomes
#19
Yu Wang, Guogang Luo, Jing Wang, Minyu Zhu, Chi Li, Honglin Teng
OBJECTIVE: To investigate the imaging features on early postoperative MRI following percutaneous endoscopic lumbar discectomy (PELD) and their correlations with surgical outcomes. METHODS: Forty-seven patients with lumbar disc herniation who underwent PELD were enrolled in this study. MRI scan was undertaken at 1 week and 3 months after surgery. Imaging features on these MRI were evaluated. Clinical factors which may affect surgical outcomes were recorded. Multivariate logistical regression analysis was performed to assess all potential factors affecting short-term and mid-term outcomes after PELD...
December 16, 2017: World Neurosurgery
https://www.readbyqxmd.com/read/29250152/therapeutic-effect-of-percutaneous-endoscopic-lumbar-discectomy-on-lumbar-disc-herniation-and-its-effect-on-oxidative-stress-in-patients-with-lumbar-disc-herniation
#20
Feng Chang, Ting Zhang, Gang Gao, Chen Yu, Ping Liu, Genle Zuo, Xinhu Huang
This study investigated the therapeutic effect of percutaneous endoscopic lumbar discectomy on lumbar disc herniation, and explored its effect on oxidative stress in patients with lumbar disc herniation. One hundred and ten patients with lumbar disc herniation were selected in The Affiliated People's Hospital of Shanxi Medical University from May 2015 to May 2016. Patients were divided into control group (n=50) and observation group (n=60) according to different surgical methods. Patients in control group were subjected to traditional open discectomy, while patients in observation group were treated with percutaneous endoscopic lumbar discectomy...
January 2018: Experimental and Therapeutic Medicine
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