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https://www.readbyqxmd.com/read/28841174/purification-preliminary-characterization-and-hepatoprotective-effects-of-polysaccharides-from-dandelion-root
#1
Liangliang Cai, Dongwei Wan, Fanglian Yi, Libiao Luan
In this study, purification, preliminary characterization and hepatoprotective effects of water-soluble polysaccharides from dandelion root (DRP) were investigated. Two polysaccharides, DRP1 and DRP2, were isolated from DRP. The two polysaccharides were α-type polysaccharides and didn't contain protein. DRP1, with a molecular weight of 5695 Da, was composed of glucose, galactose and arabinose, whereas DRP2, with molecular weight of 8882 Da, was composed of rhamnose, galacturonic acid, glucose, galactose and arabinose...
August 25, 2017: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry
https://www.readbyqxmd.com/read/28724210/dandelion-root-extract-suppressed-gastric-cancer-cells-proliferation-and-migration-through-targeting-lncrna-ccat1
#2
Huanhuan Zhu, Hangyong Zhao, Linjie Zhang, Jianmin Xu, Chunhua Zhu, Hui Zhao, Guoqiang Lv
Gastric cancer (GC) is one of the most common tumors worldwide. Standard treatment after early detection involves surgical excision (recurrence is possible), and metastatic gastric cancer is refractory to immuno-, radio-, and most harmful chemotherapies. Various natural compounds have shown efficacy in killing different cancers, albeit not always specifically. In this study, we show that dandelion root extract (DRE) specifically and effectively suppresses proliferation and migration in human gastric cells without inducing toxicity in noncancerous cells...
September 2017: Biomedicine & Pharmacotherapy, Biomédecine & Pharmacothérapie
https://www.readbyqxmd.com/read/28532507/isoprenoid-biosynthesis-in-dandelion-latex-is-enhanced-by-the-overexpression-of-three-key-enzymes-involved-in-the-mevalonate-pathway
#3
Katharina M Pütter, Nicole van Deenen, Kristina Unland, Dirk Prüfer, Christian Schulze Gronover
BACKGROUND: Latex from the dandelion species Taraxacum brevicorniculatum contains many high-value isoprenoid end products, e.g. triterpenes and polyisoprenes such as natural rubber. The isopentenyl pyrophosphate units required as precursors for these isoprenoids are provided by the mevalonate (MVA) pathway. The key enzyme in this pathway is 3-hydroxy-methyl-glutaryl-CoA reductase (HMGR) and its activity has been thoroughly characterized in many plant species including dandelion. However, two enzymes acting upstream of HMGR have not been characterized in dandelion latex: ATP citrate lyase (ACL), which provides the acetyl-CoA utilized in the MVA pathway, and acetoacetyl-CoA thiolase (AACT), which catalyzes the first step in the pathway to produce acetoacetyl-CoA...
May 22, 2017: BMC Plant Biology
https://www.readbyqxmd.com/read/28260050/taraxacum%C3%A2-coreanum-protects-against-glutamate-induced-neurotoxicity-through-heme-oxygenase-1-expression-in-mouse-hippocampal-ht22-cells
#4
Chi-Su Yoon, Wonmin Ko, Dong-Sung Lee, Dong-Cheol Kim, Jongsu Kim, Moonbum Choi, Jin Seon Beom, Ren-Bo An, Hyuncheol Oh, Youn-Chul Kim
Taraxacum coreanum Nakai is a dandelion that is native to Korea, and is widely used as an edible and medicinal herb. The present study revealed the neuroprotective effect of this plant against glutamate-induced oxidative stress in HT22 murine hippocampal neuronal cells. Ethanolic extracts from the aerial (TCAE) and the root parts (TCRE) of T. coreanum were prepared. Both extracts were demonstrated, by high performance liquid chromatography, to contain caffeic acid and ferulic acid as representative constituents...
April 2017: Molecular Medicine Reports
https://www.readbyqxmd.com/read/28026992/sesquiterpene-lactone-composition-and-cellular-nrf2-induction-of-taraxacum-officinale-leaves-and-roots-and-taraxinic-acid-%C3%AE-d-glucopyranosyl-ester
#5
Tuba Esatbeyoglu, Betina Obermair, Tabea Dorn, Karsten Siems, Gerald Rimbach, Marc Birringer
Taraxacum officinale, the common dandelion, is a plant of the Asteraceae family, which is used as a food and medical herb. Various secondary plant metabolites such as sesquiterpene lactones, triterpenoids, flavonoids, phenolic acids, coumarins, and steroids have been described to be present in T. officinale. Dandelion may exhibit various health benefits, including antioxidant, anti-inflammatory, and anticarcinogenic properties. We analyzed the leaves and roots of the common dandelion (T. officinale) using high-performance liquid chromatography/mass spectrometry to determine its sesquiterpene lactone composition...
January 2017: Journal of Medicinal Food
https://www.readbyqxmd.com/read/27885764/development-of-rubber-enriched-dandelion-varieties-by-metabolic-engineering-of-the-inulin-pathway
#6
Anna Stolze, Alan Wanke, Nicole van Deenen, Roland Geyer, Dirk Prüfer, Christian Schulze Gronover
Natural rubber (NR) is an important raw material for a large number of industrial products. The primary source of NR is the rubber tree Hevea brasiliensis, but increased worldwide demand means that alternative sustainable sources are urgently required. The Russian dandelion (Taraxacum koksaghyz Rodin) is such an alternative because large amounts of NR are produced in its root system. However, rubber biosynthesis must be improved to develop T. koksaghyz into a commercially feasible crop. In addition to NR, T...
June 2017: Plant Biotechnology Journal
https://www.readbyqxmd.com/read/27566846/dandelion-taraxacum-linearisquameum-does-not-reflect-soil-metal-content-in-urban-localities
#7
Jozef Kováčik, Matej Dudáš, Josef Hedbavny, Pavol Mártonfi
Accumulation of selected heavy metals (Cd, Pb, Ni, Cr, Fe, and Zn) and phenolic metabolites (total soluble phenols, cichoric and caftaric acid) in dandelion organs (leaves, roots, inflorescences/anthodia) collected from six localities within the industrial town Košice (eastern Slovakia) were studied. Localities from the vicinity of a steel factory (Cd, Fe) and heavy traffic (Pb, Ni, Cr, Zn) contained the highest amount of individual metals in the soil but a significant correlation between soil and organ metal content was found only for Cr in the leaves (r(2) = 0...
November 2016: Environmental Pollution
https://www.readbyqxmd.com/read/27564258/dandelion-root-extract-affects-colorectal-cancer-proliferation-and-survival-through-the-activation-of-multiple-death-signalling-pathways
#8
Pamela Ovadje, Saleem Ammar, Jose-Antonio Guerrero, John Thor Arnason, Siyaram Pandey
Dandelion extracts have been studied extensively in recent years for its anti-depressant and anti-inflammatory activity. Recent work from our lab, with in-vitro systems, shows the anti-cancer potential of an aqueous dandelion root extract (DRE) in several cancer cell models, with no toxicity to non-cancer cells. In this study, we examined the cancer cell-killing effectiveness of an aqueous DRE in colon cancer cell models. Aqueous DRE induced programmed cell death (PCD) selectively in > 95% of colon cancer cells, irrespective of their p53 status, by 48 hours of treatment...
November 8, 2016: Oncotarget
https://www.readbyqxmd.com/read/27082473/when-it-comes-to-new-bits-of-kit-we-are-all-kids-at-heart
#9
(no author information available yet)
Last weekend I went to the garden centre and bought myself a fancy tool for pulling up dandelions and thistles without breaking their roots.
May 25, 2011: Nursing Standard
https://www.readbyqxmd.com/read/27031531/streptosporangium-jiaoheense-sp-nov-and-streptosporangium-taraxaci-sp-nov-actinobacteria-isolated-from-soil-and-dandelion-root-taraxacum-mongolicum-hand-mazz
#10
Junwei Zhao, Lifeng Guo, Zhilei Li, Chenyu Piao, Yao Li, Jiansong Li, Chongxi Liu, Xiangjing Wang, Wensheng Xiang
Two novel actinobacteria, designated strains NEAU-Jh1-4T and NEAU-Wp2-0T, were isolated from muddy soil collected from a riverbank in Jiaohe and a dandelion root collected from Harbin, respectively. A polyphasic study was carried out to establish the taxonomic positions of these two strains. The phylogenetic analysis based on the 16S rRNA gene sequences of strains NEAU-Jh1-4T and NEAU-Wp2-0T indicated that strain NEAU-Jh1-4T clustered with Streptosporangium nanhuense NEAU-NH11T (99.32 % 16S rRNA gene sequence similarity), Streptosporangium purpuratum CY-15110T (98...
June 2016: International Journal of Systematic and Evolutionary Microbiology
https://www.readbyqxmd.com/read/26950922/optimization-of-methyl-jasmonate-and-%C3%AE-cyclodextrin-for-enhanced-production-of-taraxerol-and-taraxasterol-in-taraxacum-officinale-weber-cultures
#11
Kiran Sharma, Rasheeduz Zafar
CONTEXT: Taraxacum officinale Weber (TO) commonly known as "dandelion", is a tropical Asian medicinal plant which contains taraxasterol (TX) and taraxerol (TA) in its roots, which are reported to be commercially important anticancer compounds. OBJECTIVE: The main objective of the present study was to evaluate the increase in yield of TX and TA through elicitation by addition of abiotic elictors like methyl jasmonate (MJ) and β-cyclodextrin (CD), to the root callus suspension cultures of TO...
June 2016: Plant Physiology and Biochemistry: PPB
https://www.readbyqxmd.com/read/26731567/a-latex-metabolite-benefits-plant-fitness-under-root-herbivore-attack
#12
Meret Huber, Janina Epping, Christian Schulze Gronover, Julia Fricke, Zohra Aziz, Théo Brillatz, Michael Swyers, Tobias G Köllner, Heiko Vogel, Almuth Hammerbacher, Daniella Triebwasser-Freese, Christelle A M Robert, Koen Verhoeven, Veronica Preite, Jonathan Gershenzon, Matthias Erb
Plants produce large amounts of secondary metabolites in their shoots and roots and store them in specialized secretory structures. Although secondary metabolites and their secretory structures are commonly assumed to have a defensive function, evidence that they benefit plant fitness under herbivore attack is scarce, especially below ground. Here, we tested whether latex secondary metabolites produced by the common dandelion (Taraxacum officinale agg.) decrease the performance of its major native insect root herbivore, the larvae of the common cockchafer (Melolontha melolontha), and benefit plant vegetative and reproductive fitness under M...
January 2016: PLoS Biology
https://www.readbyqxmd.com/read/26576225/dandelion-extracts-protect-human-skin-fibroblasts-from-uvb-damage-and-cellular-senescence
#13
Yafan Yang, Shuangshuang Li
Ultraviolet (UV) irradiation causes damage in skin by generating excessive reactive oxygen species (ROS) and induction of matrix metalloproteinases (MMPs), leading to skin photoageing. Dandelion extracts have long been used for traditional Chinese medicine and native American medicine to treat cancers, hepatitis, and digestive diseases; however, less is known on the effects of dandelion extracts in skin photoageing. Here we found that dandelion leaf and flower extracts significantly protect UVB irradiation-inhibited cell viability when added before UVB irradiation or promptly after irradiation...
2015: Oxidative Medicine and Cellular Longevity
https://www.readbyqxmd.com/read/26254898/dandelion-taraxacum-officinale-and-agrimony-agrimonia-eupatoria-as-indicators-of-geogenic-contamination-of-flysch-soils-in-eastern-slovakia
#14
Ján Čurlík, Martin Kolesár, Ondrej Ďurža, Edgar Hiller
Contents of potentially toxic elements Fe, Mn, Cr, Ni, Co, V, Cu, and Mo were determined in common dandelion (Taraxacum officinale) and agrimony (Agrimonia eupatoria) to show their usefulness as bioindicators of geogenic soil pollution. Both plants were collected on geochemically anomalous soils developed on flysch sedimentary rocks (Paleogene) of Eastern Slovakia, which also are composed of weathered detritus of some ultramafic rocks. Generally, contents of the investigated association of potentially toxic elements are highly increased in these "serpentine"-like soils...
April 2016: Archives of Environmental Contamination and Toxicology
https://www.readbyqxmd.com/read/26125671/weeds-ability-to-phytoremediate-cadmium-contaminated-soil
#15
Hossein Hammami, Mehdi Parsa, Mohammad Hassan Rashed Mohassel, Salman Rahimi, Sajad Mijani
An alternative method to other technologies to clean up the soil, air and water pollution by heavy metals is phytoremediation. Therefore, a pot culture experiment was conducted at the College of Agriculture, Ferdowsi University of Mashhad, Mashhad, Iran, in 2014 to determine the potential absorption of cadmium by Portulaca oleracea (Common purslane), Solanum nigrum (Black nightshade), Abutilon theophrasti (Velvetleaf) and Taraxacum officinale (Dandelion). The type of experiment was completely randomized design with factorial arrangement and four replications...
2016: International Journal of Phytoremediation
https://www.readbyqxmd.com/read/25795090/novel-set-up-for-low-disturbance-sampling-of-volatile-and-non-volatile-compounds-from-plant-roots
#16
Elisabeth J Eilers, Gerhard Pauls, Matthias C Rillig, Bill S Hansson, Monika Hilker, Andreas Reinecke
Most studies on rhizosphere chemicals are carried out in substrate-free set-ups or in artificial substrates using sampling methods that require an air flow and may thus cause disturbance to the rhizosphere. Our study aimed to develop a simplified and inexpensive system that allows analysis of rhizosphere chemicals at experimentally less disturbed conditions. We designed a mesocosm in which volatile rhizosphere chemicals were sampled passively (by diffusion) without air- and water flow on polydimethylsiloxane-(PDMS) tubes...
March 2015: Journal of Chemical Ecology
https://www.readbyqxmd.com/read/25682510/identification-quantification-spatiotemporal-distribution-and-genetic-variation-of-major-latex-secondary-metabolites-in-the-common-dandelion-taraxacum-officinale-agg
#17
Meret Huber, Daniella Triebwasser-Freese, Michael Reichelt, Sven Heiling, Christian Paetz, Jima N Chandran, Stefan Bartram, Bernd Schneider, Jonathan Gershenzon, Matthias Erb
The secondary metabolites in the roots, leaves and flowers of the common dandelion (Taraxacum officinale agg.) have been studied in detail. However, little is known about the specific constituents of the plant's highly specialized laticifer cells. Using a combination of liquid and gas chromatography, mass spectrometry and nuclear magnetic resonance spectrometry, we identified and quantified the major secondary metabolites in the latex of different organs across different growth stages in three genotypes, and tested the activity of the metabolites against the generalist root herbivore Diabrotica balteata...
July 2015: Phytochemistry
https://www.readbyqxmd.com/read/25644491/characterisation-of-antimicrobial-extracts-from-dandelion-root-taraxacum-officinale-using-lc-spe-nmr
#18
O Kenny, N P Brunton, D Walsh, C M Hewage, P McLoughlin, T J Smyth
Plant extracts have traditionally been used as sources of natural antimicrobial compounds, although in many cases, the compounds responsible for their antimicrobial efficacy have not been identified. In this study, crude and dialysed extracts from dandelion root (Taraxacum officinale) were evaluated for their antimicrobial properties against Gram positive and Gram negative bacterial strains. The methanol hydrophobic crude extract (DRE3) demonstrated the strongest inhibition of microbial growth against Staphylococcus aureus, methicillin-resistant S...
April 2015: Phytotherapy Research: PTR
https://www.readbyqxmd.com/read/25644367/heterologous-expression-of-chloroplast-localized-geranylgeranyl-pyrophosphate-synthase-confers-fast-plant-growth-early-flowering-and-increased-seed-yield
#19
Sandeep Kumar Tata, Jihye Jung, Yoon-Ha Kim, Jun Young Choi, Ji-Yul Jung, In-Jung Lee, Jeong Sheop Shin, Stephen Beungtae Ryu
Geranylgeranyl pyrophosphate synthase (GGPS) is a key enzyme for a structurally diverse class of isoprenoid biosynthetic metabolites including gibberellins, carotenoids, chlorophylls and rubber. We expressed a chloroplast-targeted GGPS isolated from sunflower (Helianthus annuus) under control of the cauliflower mosaic virus 35S promoter in tobacco (Nicotiana tabacum). The resulting transgenic tobacco plants expressing heterologous GGPS showed remarkably enhanced growth (an increase in shoot and root biomass and height), early flowering, increased number of seed pods and greater seed yield compared with that of GUS-transgenic lines (control) or wild-type plants...
January 2016: Plant Biotechnology Journal
https://www.readbyqxmd.com/read/25559021/production-of-inulinase-fructosyltransferase-and-sucrase-from-fungi-on-low-value-inulin-rich-substrates-and-their-use-in-generation-of-fructose-and-fructo-oligosaccharides
#20
Hemant Kumar Rawat, Mohd Anis Ganaie, Naveen Kango
Owing to applications in the food and nutraceutical industries, inulinases, fructosyltransferases and sucrases have gained considerable attention in recent times. Twenty-five fungal strains were screened for production of these enzymes on three different media formulated using inulin-rich plant extracts prepared from asparagus root, dahlia tuber and dandelion root extract. Culture filtrates of the fungi were examined for hydrolytic activities. Fungi belonging to genus Aspergillus, A. niger GNCC 2655 (11.3 U/ml), A...
March 2015: Antonie Van Leeuwenhoek
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