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https://www.readbyqxmd.com/read/27885077/highlights-of-the-russian-health-studies-program-and-updated-research-findings
#1
Barrett N Fountos
Recognized for conducting cutting-edge science in the field of radiation health effects research, the Department of Energy's (DOE) Russian Health Studies Program has continued to generate excitement and enthusiasm throughout its 23-year mission to assess worker and public health risks from radiation exposure resulting from nuclear weapons production activities in the former Soviet Union. The three goals of the Program are to: (1) clarify the relationship between health effects and chronic, low-to-medium dose radiation exposure; (2) estimate the cancer risks from exposure to gamma, neutron, and alpha radiation; and (3) provide information to the national and international organizations that determine radiation protection standards and practices...
November 24, 2016: Radiation Protection Dosimetry
https://www.readbyqxmd.com/read/27881792/estimates-of-radiation-doses-to-the-skin-for-people-camped-at-wallatinna-during-the-uk-totem-1-atomic-weapons-test
#2
G A Williams, R S O'Brien, M Grzechnik, K N Wise
A group of Aboriginal people was camped at Wallatinna in South Australia, ~170 km downwind from Emu Field, where an atomic test (the Totem 1 test) was carried out at 07.00 on 15 October 1953 local time (21.30 on 14 October 1953 GMT (Greenwich Mean Time)). They left the camp ~24 hours later. These people stated that a phenomenon that has become known as a 'black mist' rolled through their camp site ~5 hours after detonation and that some of them subsequently became sick, displaying skin reddening and nausea...
November 23, 2016: Radiation Protection Dosimetry
https://www.readbyqxmd.com/read/27849500/the-u-s-army-occupational-and-environmental-medicine-residency-at-aberdeen-proving-ground-maryland-1960-1996
#3
Joel C Gaydos, Timothy M Mallon, William A Rice
BACKGROUND: Reorganization of the Army and critical assessment of Army Graduate Medical Education programs prompted the Occupational and Environmental Medicine (OEM) Consultant to the Army Surgeon General to initiate a review of current Army OEM residency training. Available information indicated the Army OEM residency at Aberdeen Proving Ground, MD, was the first and longest operating Army OEM residency. Describing this residency was identified as the first step in the review, with the objectives of determining why the residency was started and sustained and its relevance to the needs of the Army...
November 2016: Military Medicine
https://www.readbyqxmd.com/read/27792232/technetium-incorporation-in-scheelite-insights-from-first-principles
#4
Matthew Ackerman, Eunja Kim, Philippe F Weck, Wendy Chernesky, Kenneth R Czerwinski
Atomistic investigations of crystalline scheelite, CaWO4, and (99)Tc-bearing scheelite, CaWO4:Tc, have been carried out using density functional theory. The lattice constants, bulk modulus, and volume compression data of CaWO4 have been calculated and compared with experimental data, with a focus on predictive understanding of (99)Tc incorporation in CaWO4. Defect formation energies have been computed for several possible interstitial (I) and substitutional (S) sites of (99)Tc in CaWO4. Both I(Oh) and S(W) sites were found to be energetically favourable for Tc doping...
October 28, 2016: Dalton Transactions: An International Journal of Inorganic Chemistry
https://www.readbyqxmd.com/read/27762064/ccnd1-bcl2-gene-network-a-direct-target-of-amifostine-in-human-acute-megakaryocytic-leukemia-cells
#5
Feng Zhang, Bo Yang, Kailiang Zhang, Mei-Ling Hou, Xue-Chun Lu, Yu-Xin Li
Amifostine (AMF), 2-(3-Aminopropyl) aminoethyl phosphorothioate is a broad-spectrum cytoprotective agent used to treat nuclear radiation and chemical weapon injuries. Recently, amifostine has been shown to have a profound biological influence on tumor cells. In order to examine the effects and mechanisms underlying the effects of amifostine on human acute megakaryocytic leukemia, we evaluated the efficacy of amifostine against Dami cells and observed a cell cycle arrest in G2 /M phase. Amifostine treatment also induced cell apoptosis of Dami cells which corresponds to formal studies...
October 19, 2016: Chemical Biology & Drug Design
https://www.readbyqxmd.com/read/27723529/experimental-evidence-for-ternary-colloid-facilitated-transport-of-th-iv-with-hematite-%C3%AE-fe2o3-colloids-and-suwannee-river-fulvic-acid
#6
Hilary P Emerson, Katherine A Hickok, Brian A Powell
Previous field experiments have suggested colloid-facilitated transport via inorganic and organic colloids as the primary mechanism of enhanced actinide transport in the subsurface at former nuclear weapons facilities. In this work, research was guided by the hypothesis that humic substances can enhance tetravalent actinide (An(IV)) migration by coating and mobilizing natural colloids in environmental systems and increasing An(IV) sorption to colloids. This mechanism is expected to occur under relatively acidic conditions where organic matter can sorb and coat colloid surfaces and facilitate formation of ternary colloid-ligand-actinide complexes...
December 2016: Journal of Environmental Radioactivity
https://www.readbyqxmd.com/read/27721136/reconstructing-surface-ocean-circulation-with-129-i-time-series-records-from-corals
#7
Ching-Chih Chang, George S Burr, A J Timothy Jull, Joellen L Russell, Dana Biddulph, Lara White, Nancy G Prouty, Yue-Gau Chen, Chuan-Chou Shen, Weijian Zhou, Doan Dinh Lam
The long-lived radionuclide (129)I (half-life: 15.7 × 10(6) yr) is well-known as a useful environmental tracer. At present, the global (129)I in surface water is about 1-2 orders of magnitude higher than pre-1960 levels. Since the 1990s, anthropogenic (129)I produced from industrial nuclear fuels reprocessing plants has been the primary source of (129)I in marine surface waters of the Atlantic and around the globe. Here we present four coral (129)I time series records from: 1) Con Dao and 2) Xisha Islands, the South China Sea, 3) Rabaul, Papua New Guinea and 4) Guam...
December 2016: Journal of Environmental Radioactivity
https://www.readbyqxmd.com/read/27720254/the-application-of-iron-based-technologies-in-uranium-remediation-a-review
#8
Anwei Chen, Cui Shang, Jihai Shao, Jiachao Zhang, Hongli Huang
Remediating uranium contamination is of worldwide interest because of the increasing release of uranium from mining and processing, nuclear power leaks, depleted uranium components in weapons production and disposal, and phosphate fertilizer in agriculture activities. Iron-based technologies are attractive because they are highly efficient, inexpensive, and readily available. This paper provides an overview of the current literature that addresses the application of iron-based technologies in the remediation of sites with elevated uranium levels...
October 5, 2016: Science of the Total Environment
https://www.readbyqxmd.com/read/27649477/a-physical-zero-knowledge-object-comparison-system-for-nuclear-warhead-verification
#9
Sébastien Philippe, Robert J Goldston, Alexander Glaser, Francesco d'Errico
Zero-knowledge proofs are mathematical cryptographic methods to demonstrate the validity of a claim while providing no further information beyond the claim itself. The possibility of using such proofs to process classified and other sensitive physical data has attracted attention, especially in the field of nuclear arms control. Here we demonstrate a non-electronic fast neutron differential radiography technique using superheated emulsion detectors that can confirm that two objects are identical without revealing their geometry or composition...
September 20, 2016: Nature Communications
https://www.readbyqxmd.com/read/27574325/use-of-clinical-decision-guidance-as-a-new-public-health-tool-for-the-medical-management-of-internal-contamination-in-radiological-mass-casualty-scenarios
#10
Albert L Wiley
This review is a discussion of special issues associated with the medical and public health management of persons at risk of internal contamination from radionuclides, following various radiological mass-casualty scenarios, as well as definition, discussion and use of the Clinical Decision Guidance (CDG) in such scenarios. Specific medical countermeasures are available for reducing the internal radiation dose and the subsequent stochastic and deterministic risks to persons internally contaminated with radionuclides from nuclear power plant, fuel processing and nuclear weapon accidents/incidents...
September 2016: Radiation Protection Dosimetry
https://www.readbyqxmd.com/read/27548999/fate-of-plutonium-at-a-former-nuclear-testing-site-in-australia
#11
Atsushi Ikeda-Ohno, Lida Mokhber Shahin, Daryl L Howard, Richard N Collins, Timothy E Payne, Mathew P Johansen
A series of the British nuclear tests conducted on mainland Australia between 1953 and 1963 dispersed long-lived radioactivity and nuclear weapons debris including plutonium (Pu), the legacy of which is a long-lasting source of radioactive contamination to the surrounding biosphere. A reliable assessment of the environmental impact of Pu contaminants and their implications for human health requires an understanding of their physical/chemical characteristics at the molecular scale. In this study, we identify the chemical form of the Pu remaining in the local soils at the Taranaki site, one of the former nuclear testing sites at Maralinga, South Australia...
September 6, 2016: Environmental Science & Technology
https://www.readbyqxmd.com/read/27532886/therapy-emergent-drug-resistance-to-integrase-strand-transfer-inhibitors-in-hiv-1-patients-a-subgroup-meta-analysis-of-clinical-trials
#12
Jiangzhou You, Hongren Wang, Xiaojun Huang, Zhen Qin, Zhaomin Deng, Jun Luo, Baoning Wang, Mingyuan Li
BACKGROUND: Integrase strand transfer inhibitors (INSTIs) are a novel class of anti-HIV agents that show high activity in inhibiting HIV-1 replication. Currently, licensed INSTIs include raltegravir (RAL), elvitegravir (EVG) and dolutegravir (DTG); these drugs have played a critical role in AIDS therapy, serving as additional weapons in the arsenal for treating patients infected with HIV-1. To date, long-term data regarding clinical experience with INSTI use and the emergence of resistance remain scarce...
2016: PloS One
https://www.readbyqxmd.com/read/27521903/radionuclide-observables-for-the-platte-underground-nuclear-explosive-test-on-14-april-1962
#13
Jonathan L Burnett, Brian D Milbrath
Past nuclear weapon explosive tests provide invaluable information for understanding the radionuclide observables expected during an On-site Inspection (OSI) for the Comprehensive Nuclear-Test-Ban Treaty (CTBT). These radioactive signatures are complex and subject to spatial and temporal variability. The Platte underground nuclear explosive test on 14 April 1962 provides extensive environmental monitoring data that can be modelled and used to calculate the maximum time available for detection of the OSI-relevant radionuclides...
November 2016: Journal of Environmental Radioactivity
https://www.readbyqxmd.com/read/27510421/intracellular-localization-of-dr5-and-related-regulatory-pathways-as-a-mechanism-of-resistance-to-trail-in-cancer
#14
Ufuk Mert, Ahter Dilsad Sanlioglu
TNF-related apoptosis-inducing ligand (TRAIL) is a prominent cytokine capable of inducing apoptosis. It can bind to five different cognate receptors, through which diverse intracellular pathways can be activated. TRAIL's ability to preferentially kill transformed cells makes it a promising potential weapon for targeted tumor therapy. However, recognition of several resistance mechanisms to TRAIL-induced apoptosis has indicated that a thorough understanding of the details of TRAIL biology is still essential before this weapon can be confidently unleashed...
August 10, 2016: Cellular and Molecular Life Sciences: CMLS
https://www.readbyqxmd.com/read/27450248/plutonium-isotopes-in-the-atmosphere-of-central-europe-isotopic-composition-and-time-evolution-vs-circulation-factors
#15
Renata Kierepko, Jerzy W Mietelski, Zbigniew Ustrnul, Robert Anczkiewicz, Herbert Wershofen, Zoltan Holgye, Jacek Kapała, Krzysztof Isajenko
This paper reports evidence of Pu isotopes in the lower part of the troposphere of Central Europe. The data were obtained based on atmospheric aerosol fraction samples collected from four places in three countries (participating in the informal European network known as the Ring of Five (Ro5)) forming a cell with a surface area of about 200,000km(2). We compared our original data sets from Krakow (Poland, 1990-2007) and Bialystok (Poland, 1991-2007) with the results from two other locations, Prague (Czech Republic; 1997-2004) and Braunschweig (Germany; 1990-2003) to find time evolution of the Pu isotopes...
November 1, 2016: Science of the Total Environment
https://www.readbyqxmd.com/read/27432959/physical-cryptographic-verification-of-nuclear-warheads
#16
R Scott Kemp, Areg Danagoulian, Ruaridh R Macdonald, Jayson R Vavrek
How does one prove a claim about a highly sensitive object such as a nuclear weapon without revealing information about the object? This paradox has challenged nuclear arms control for more than five decades. We present a mechanism in the form of an interactive proof system that can validate the structure and composition of an object, such as a nuclear warhead, to arbitrary precision without revealing either its structure or composition. We introduce a tomographic method that simultaneously resolves both the geometric and isotopic makeup of an object...
August 2, 2016: Proceedings of the National Academy of Sciences of the United States of America
https://www.readbyqxmd.com/read/27420080/emerging-environmental-justice-issues-in-nuclear-power-and-radioactive-contamination
#17
Dean Kyne, Bob Bolin
Nuclear hazards, linked to both U.S. weapons programs and civilian nuclear power, pose substantial environment justice issues. Nuclear power plant (NPP) reactors produce low-level ionizing radiation, high level nuclear waste, and are subject to catastrophic contamination events. Justice concerns include plant locations and the large potentially exposed populations, as well as issues in siting, nuclear safety, and barriers to public participation. Other justice issues relate to extensive contamination in the U...
2016: International Journal of Environmental Research and Public Health
https://www.readbyqxmd.com/read/27359098/measurements-of-cesium-in-arctic-beluga-and-caribou-before-and-after-the-fukushima-accident-of-2011
#18
T J Stocki, M Gamberg, L Loseto, E Pellerin, L Bergman, J-F Mercier, L Genovesi, M Cooke, B Todd, D Sandles, J Whyte, X Wang
Concern from northern communities following the Fukushima Daiichi nuclear accident of March 2011 has prompted a reassessment of the safety of their traditional foods with respect to radioactivity levels. To this end, a study was conducted to measure the levels of radionuclides in Arctic caribou (Rangifer tarandus) and beluga (Delphinapterus leucas). The main radionuclide of concern is cesium-137, which is easily transferred through the lichen-caribou food chain. Previous studies have been conducted on the cesium-137 levels in Canadian caribou herds from 1958 to 2000, allowing researchers to determine the amount of cesium-137 in caribou specifically attributable to atmospheric weapons testing and the Chernobyl nuclear accident in 1986...
October 2016: Journal of Environmental Radioactivity
https://www.readbyqxmd.com/read/27356721/reduced-ovarian-cancer-incidence-in-women-exposed-to-low-dose-ionizing-background-radiation-or-radiation-to-the-ovaries-after-treatment-for-breast-cancer-or-rectosigmoid-cancer
#19
Steven Lehrer, Sheryl Green, Kenneth E Rosenzweig
BACKGROUND: High dose ionizing radiation can induce ovarian cancer, but the effect of low dose radiation on the development of ovarian cancer has not been extensively studied. We evaluated the effect of low dose radiation and total background radiation, and the radiation delivered to the ovaries during the treatment of rectosigmoid cancer and breast cancer on ovarian cancer incidence. MATERIALS AND METHODS: Background radiation measurements are from Assessment of Variations in Radiation Exposure in the United States, 2011...
2016: Asian Pacific Journal of Cancer Prevention: APJCP
https://www.readbyqxmd.com/read/27355245/mortality-among-military-participants-at-the-1957-plumbbob-nuclear-weapons-test-series-and-from-leukemia-among-participants-at-the-smoky-test
#20
Glyn G Caldwell, Matthew M Zack, Michael T Mumma, Henry Falk, Clark W Heath, John E Till, Heidi Chen, John D Boice
Health effects following low doses of ionizing radiation are uncertain. Military veterans at the Nevada test site (NTS) during the SMOKY atmospheric nuclear weapons test in 1957 were reported to be at increased risk for leukemia in 1979, but this increase was not evaluated with respect to radiation dose. The SMOKY test was one of 30 tests in 1957 within the PLUMBBOB test series. These early studies led to public laws where atomic veterans could qualify for compensation for presumptive radiogenic diseases. A retrospective cohort study was conducted of 12219 veterans at the PLUMBBOB test series, including 3020 at the SMOKY nuclear test...
September 2016: Journal of Radiological Protection: Official Journal of the Society for Radiological Protection
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