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https://www.readbyqxmd.com/read/27920712/hypertrophic-pachymeningitis-as-an-early-manifestation-of-relapsing-polychondritis-case-report-and-review-of-the-literature
#1
Satoru Ushiyama, Tomomi Kinoshita, Yasuhiro Shimojima, Nobuhiko Ohashi, Dai Kishida, Daigo Miyazaki, Katsuya Nakamura, Yoshiki Sekijima, Shu-Ichi Ikeda
Neurological involvement in relapsing polychondritis (RP) is relatively rare. We describe the case of an 80-year-old man who presented with hypertrophic pachymeningitis (HP) together with arthritis as the first manifestation of RP. Auricular chondritis, which subsequently determined the diagnosis of RP, occurred a few weeks after the detection of HP. The neurological symptoms, as well as arthritis, were promptly improved by treatment with corticosteroids. It is generally difficult to diagnose RP in the absence of typical cartilaginous involvement; however, the present case suggests that HP may occur as an early clinical manifestation of RP...
September 2016: Case Reports in Neurology
https://www.readbyqxmd.com/read/27708954/relapsing-polychondritis
#2
Hakan Emmungil, Sibel Zehra Aydın
Relapsing polychondritis (RPC) is a unique and rarely observed autoimmune condition regarded as recurrent extensive chondritis of the auricular, nasal, and tracheal cartilages. Moreover, heart, main arteries, skin, and eyes may be involved. Several forms of clinical manifestations may be seen, and the pathogenesis still remains anonymous. A concomitant disease, particularly myelodysplasia or other systemic autoimmune disease can be detected in one-third of the patients with RPC. The treatment of RPC should be considered on personal basis and classified according to disease activity and severity...
December 2015: European Journal of Rheumatology
https://www.readbyqxmd.com/read/27658578/laryngeal-chondritis-in-sheep-in-iceland
#3
Ó G Sigurðardóttir, E Jörundsson, V Friðriksdóttir
Laryngeal chondritis is a chronic disease in sheep with low morbidity, high mortality and unresolved pathogenesis. The disease has been recognized recently in Iceland and affects both ewes and rams. Animals of different ages are affected, but lambs and yearlings predominate. The disease is seen in housed animals and most cases occur during the late winter months. We report the gross and microscopical findings in 45 cases of laryngeal chondritis in Icelandic sheep.
November 2016: Journal of Comparative Pathology
https://www.readbyqxmd.com/read/27596713/bacterial-chondritis-complications-following-ear-piercing
#4
G Bellaud, A Canestri, S Gallah, M Merlant, S Cousseau, M G Lebrette, L Slama, G Pialoux
BACKGROUND: Body piercing has become widespread and is associated with increased complications. Post-piercing chondritis may lead to severe residual deformity. We aimed to report case patients presenting with post-piercing chondritis in our department and to describe clinical features and treatment. PATIENTS AND METHODS: We conducted a retrospective study of patients presenting with post-piercing chondritis in the infectious disease department of Tenon Hospital, Paris, France...
September 2, 2016: Médecine et Maladies Infectieuses
https://www.readbyqxmd.com/read/27484467/inflammatory-bowel-disease-mimicking-granulomatosis-with-polyangiitis-a-case-report
#5
Samantha C Shapiro, Armen Khararjian, Rebecca L Manno
BACKGROUND: We report a case in which the extraintestinal manifestations of inflammatory bowel disease preceded development of gastrointestinal symptoms by nearly 9 months in the context of an unusual autoantibody panel, mimicking granulomatosis with polyangiitis. This case highlights the intricacies and overlap of autoimmune diseases, and illustrates an interesting clinical phenotype: cytoplasmic anti-neutrophil cytoplasmic antibody positive inflammatory bowel disease with predominantly extraintestinal manifestations...
2016: Journal of Medical Case Reports
https://www.readbyqxmd.com/read/27396510/corticosteroid-therapy-for-a-patient-with-relapsing-polychondritis-complicated-by-igg4-related-disease
#6
Mari Yamasue, Shin-Ichi Nureki, Hiroyuki Matsumoto, Takamasa Kan, Takehiro Hashimoto, Ryoichi Ushijima, Yuko Usagawa, Jun-Ichi Kadota
Relapsing polychondritis (RP) is a rare systemic disorder characterized by recurrent, widespread chondritis of the auricular, nasal, and tracheal cartilages. IgG4-related disease (IgG4-RD) is a systemic immune-mediated disease characterized by the infiltration of IgG4-bearing plasma cells into systemic organs. Although 25% to 35% of patients with RP have a concurrent autoimmune disease, coexistence of RP and IgG4-RD is rare. We herein report a case of RP complicated by IgG4-RD. A 63-year-old man developed recurrent bilateral ear pain and swelling, recurrent blurred and decreased vision, and migratory multiple joint pain, sequentially within one year...
2016: Tohoku Journal of Experimental Medicine
https://www.readbyqxmd.com/read/27383615/oesophageal-lumen-ph-in-yearling-horses-and-the-effect-of-management-and-administration-of-omeprazole
#7
C S Wilson, V J Brookes, K J Hughes, G D Trope, H Ip, A J Gunn
BACKGROUND: In humans, arytenoid chondritis can be caused by chemical trauma of mucosa from gastro-oesophageal reflux. While a similar process could be involved in the aetiopathogenesis of arytenoid chondritis in horses, the oesophageal lumen pH in this species is poorly understood. OBJECTIVES: To determine if gastro-oesophageal reflux occurs in horses by characterising oesophageal lumen pH. STUDY DESIGN: Blinded, randomised, placebo-controlled, crossover, experimental study...
July 6, 2016: Equine Veterinary Journal
https://www.readbyqxmd.com/read/27375171/-cutaneous-tuberculosis-of-the-ear-due-to-mycobacterium-bovis
#8
R Lhote, L Raskine, J Gottlieb, F Mougari, M Lafaurie, M-D Vignon-Pennamen, M Bagot, A Petit, F Cordoliani
INTRODUCTION: Isolated cutaneous tuberculosis is uncommon, accounting for only 0.14 to 5% of Mycobacterium tuberculosis infections. We report a rare case of ear cutaneous tuberculosis due to Mycobacterium bovis in an immunocompetent woman. CASE REPORT: A 59-year-old woman presented an erythematous and scaly lesion of the ear present for two years. The histological findings were compatible with a diagnosis of sarcoidosis, with non-necrotic granuloma. After failure of dermal corticosteroid therapy, a further biopsy identified M...
October 2016: Annales de Dermatologie et de Vénéréologie
https://www.readbyqxmd.com/read/27331771/relapsing-polychondritis-can-be-characterized-by-3-different-clinical-phenotypes-analysis-of-a-recent-series-of-142-patients
#9
Jérémie Dion, Nathalie Costedoat-Chalumeau, Damien Sène, Judith Cohen-Bittan, Gaëlle Leroux, Charlotte Dion, Camille Francès, Jean-Charles Piette
OBJECTIVE: Relapsing polychondritis is a rare condition characterized by recurrent inflammation of cartilaginous tissues and systemic manifestations. Data on this disease remain scarce. METHODS: Retrospective study of patients with relapsing polychondritis seen between 2000 and 2012 in a single center, to describe patient characteristics and disease evolution, identify prognostic factors and define different clinical phenotypes. RESULTS: We included 142 patients with chondritis types (86 women [61%]; mean age at first symptoms 43...
June 22, 2016: Arthritis & Rheumatology
https://www.readbyqxmd.com/read/27293269/mouth-and-genital-ulcers-with-inflamed-cartilage-syndrome-case-report-and-review-of-the-published-work
#10
Yuka Kaneko, Noriaki Nakai, Takashi Kida, Yutaka Kawahito, Norito Katoh
Mouth and genital ulcers with inflamed cartilage (MAGIC) syndrome are disease that fulfilled criteria for diagnosis of Behcet's disease (BD) and relapsing polychondritis (RP). We report a 22-year-old Japanese woman presented with MAGIC syndrome and we described the clinicopathological characteristics of MAGIC syndrome based on a review of published cases from July 1985 to December 2015. In our case, the patient with oral aphthae, erythema nodosum, acne-like eruptions, uveitis, and polyarthritis fulfilled criteria for diagnosis of incomplete form of BD...
May 2016: Indian Journal of Dermatology
https://www.readbyqxmd.com/read/27181548/relapsing-polychondritis-complicated-by-vasculitis-of-the-omentum
#11
Yoshitaka Kimura, Kurumi Asako, Hirotoshi Kikuchi, Kazufusa Hoshimoto, Yuko Sasajima, Hajime Kono
A 78-year-old man presented with bilateral auricular and nasal chondritis and an inner ear disorder. Relapsing polychondritis (RPC) was diagnosed and corticosteroid therapy was initiated. Two years later, he developed abdominal pain and a fever. A contrast-enhanced computed tomography scan showed enhancement of the mesentery and massive ascites. The patient underwent emergency laparotomy, which revealed inflammation and thickening of the omentum. A microscopic examination of the omentum disclosed vasculitis, and corticosteroid and cyclophosphamide pulse therapies were administered...
2016: Internal Medicine
https://www.readbyqxmd.com/read/26995500/relapsing-polychondritis-and-lymphocytic-meningitis-with-varied-neurological-symptoms
#12
Renata Dal-Prá Ducci, Francisco Manoel Branco Germiniani, Letícia Elizabeth Augustin Czecko, Eduardo S Paiva, Hélio Afonso Ghizoni Teive
BACKGROUND: Relapsing polychondritis is a rare multisystem disease characterized by bilateral auricular and nasal chondritis and vestibular involvement, additionally affecting various other organs/systems. However, Central Nervous System involvement has only been reported in a few instances. OBJECTIVE: To report the case of a patient with relapsing polychondritis and several neurological manifestations. CASE REPORT: We report the case of a 69 year-old male with a 20-day history of ataxia, paraparesis, tinnitus, vertigo and confusion...
February 5, 2016: Revista Brasileira de Reumatologia
https://www.readbyqxmd.com/read/26951051/clinical-and-prognostic-characteristics-of-158-cases-of-relapsing-polychondritis-in-china-and-review-of-the-literature
#13
Dong-Fang Lin, Wei-Qiang Yang, Ping-Ping Zhang, Qing Lv, Ou Jin, Jie-Ruo Gu
This work is aimed to study the clinical and prognostic features of relapsing polychondritis (RP) in China. A total of 158 RP cases from 1985 to 2013 in China were included and compared with international case series in terms of clinical features, systemic involvement, differential diagnosis and prognosis. (1) The average age at the onset was 45.3 years old, the average age for initial symptoms was 14.4 months, female/male ratio was 0.7:1 and misdiagnosis rate was 47 %. (2) The incidence of arthritis was lower than that in Caucasians...
July 2016: Rheumatology International
https://www.readbyqxmd.com/read/26948106/relapsing-polychondritis-in-singapore-a-case-series-and-review-of-literature
#14
Tyng Yu Chuah, Nai Lee Lui
INTRODUCTION: This study aims to describe the clinical presentation, treatment and outcome of patients with relapsing polychondritis (RP) who were seen at a large tertiary-care academic medical institution in Singapore. METHODS: The medical records of all patients diagnosed with RP by the Department of Rheumatology and Immunology, Singapore General Hospital, Singapore, between 2005 and 2013 were reviewed. The diagnosis of RP was made using the modified McAdam criteria...
March 7, 2016: Singapore Medical Journal
https://www.readbyqxmd.com/read/26929942/-18-f-fdg-pet-imaging-of-granulomatosis-with-polyangiitis-wegener-s-syndrome
#15
Frank De Geeter, Pieterjan Gykiere
OBJECTIVE: Granulomatosis with polyangiitis (GPA), formerly called Wegener's syndrome, is a vasculitis associated with antineutrophil cytoplasmic antibody and may occur in all ages but mostly in order adults. The organs most frequently involved are the ear, nose and throat (rhinitis, sinusitus, oral ulcers, chondritis), the lungs (nodules, sometimes cavitating, infiltrates, hilar adenopathy) and the kidneys (glomerulonephritis). As patients typically present with constitutional symptoms, the diagnosis can be challenging...
January 2016: Hellenic Journal of Nuclear Medicine
https://www.readbyqxmd.com/read/26878303/late-costal-osteomyelitis-with-a-cutaneous-fistula-after-flame-burns-a-case-report
#16
S Gaucher, A Bobbio, A Mansuet-Lupo, E Hamelin-Canny, A Hautier, C Nicolas, M Alifano
Chest wall defects are an unusual complication of burn injury, generally seen after high-voltage electrical burns. Here we report the case of a 57-year-old man who developed costal chondritis and osteomyelitis 23 months after flame injury, which covered 50% of the total body surface area. Management included the resection of two ribs and coverage with an omental flap, overlaid by a split-thickness skin graft during the same surgical procedure. Declaration of interest: The authors have no conflict of interest to declare...
February 2016: Journal of Wound Care
https://www.readbyqxmd.com/read/26818301/the-folded-ulnar-forearm-flap-for-nasal-reconstruction
#17
Yen-Chang Hsiao, Jung-Ju Huang, Jonathan A Zelken, Chih-Wei Wu, Chun-Shin Chang, Mohamed Abdelrahman, Georgios Kolios
BACKGROUND: Many strategies exist to reconstruct composite nasal defects, but free flaps are necessary for extensive defects. The workhorse radial forearm flap is hair-bearing and donor-site cosmesis is unfavorable. The ulnar forearm flap is overlooked despite important aesthetic benefits. The authors describe their experience with the ulnar forearm flap, with a novel folding technique in staged nasal reconstruction. METHODS: Between December of 2010 and April of 2015, 10 nasal reconstructions in five men and five women were performed...
February 2016: Plastic and Reconstructive Surgery
https://www.readbyqxmd.com/read/26739478/tympanoplasty-conchal-cavum-approach
#18
RANDOMIZED CONTROLLED TRIAL
S Christopher Man, Desmond A Nunez
UNLABELLED: The three well recognized tympanoplasty approaches: permeatal, postaural, and endaural, each have advantages and disadvantages. The permeatal approach is suitable only for ears with adequate canal size. The postaural approach limits visualization of the posterior eardrum margin. The endaural approach limits the view of the eardrum's anterior margin. This study describes a modified endaural approach, developed to overcome these limitations. A retrospective case series review and collection of a prospective cohort of patient reported outcome data were undertaken to assess the technique...
January 6, 2016: Journal of Otolaryngology—Head & Neck Surgery
https://www.readbyqxmd.com/read/26484879/preliminary-results-of-the-application-of-a-disease-activity-score-in-a-patient-with-relapsing-polychondritis
#19
A C Pinto, P A Wachholz, P Y Masuda, F B Freitas, M L Cavalcante, C T Soares
AIMS: The present study aims to report a case of Relapsing Polychondritis, using established diagnostic criteria, and evaluate preliminary results of the Relapsing Polychondritis Disease Activity Index (RPDAI), before and after treatment with a combination of corticosteroids and colchicine. CASE REPORT: Twenty one years old female with ocular photosensitivity, tearing and bilateral erythema since last pregnancy. Symptoms remitted spontaneously after pregnancy. Three months later symptoms relapsed, added to bilateral auricular chondritis (sparing ear lobe), frequent episodes of hoarseness and aphonia, and pain during esternal and chostocondral palpation...
October 20, 2015: Giornale Italiano di Dermatologia e Venereologia: Organo Ufficiale, Società Italiana di Dermatologia e Sifilografia
https://www.readbyqxmd.com/read/26340895/purulent-chondritis-of-the-cricoid
#20
C Leiva-Salinas, S Mukherjee
No abstract text is available yet for this article.
April 2016: European Annals of Otorhinolaryngology, Head and Neck Diseases
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