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https://www.readbyqxmd.com/read/29731938/treatment-of-a-patient-with-merkel-cell-skin-carcinoma-using-radiation-therapy-a-case-report
#1
Andrej Petrov, Slavica Kraleva, Katerina Kubelka-Sabit, Deva Petrova
BACKGROUND: Merkel cell carcinoma (MCC) is a rare, very aggressive tumour. The pathogenesis remains unclear, but UV radiation, immunosuppression, and the presence of Merkel cell polyomavirus in the tumour genome appear to have a key role. Merkel cell carcinoma is a highly aggressive tumour that often has a lethal end. CAS REPORT: A patient at 93 years of age comes for an examination by a dermatologist due to a rapidly growing nodular tumour growth in the forehead area...
April 15, 2018: Open Access Macedonian Journal of Medical Sciences
https://www.readbyqxmd.com/read/29686180/chromobacterium-violaceum-the-deadly-sepsis
#2
Guntur Darmawan, R N Yasmin Kusumawardhani, Bachti Alisjahbana, Trinugroho Heri Fadjari
Chromobacterium violaceum is a Gram-negative facultatively anaerobic, oxidase-positive bacterium producing a dark violet antioxidant pigment called violacein. It is an opportunistic pathogen and has an ubiquitous distribution, mainly resides in water and soil of tropical and subtropical regions.An-18-year-old man referred to the emergency room with a 5-day history of progressively worsening swelling of the right cheek. He sought consult and hospitalized at another institution for three days prior this admission; however, his condition deteriorated...
January 2018: Acta Medica Indonesiana
https://www.readbyqxmd.com/read/29664828/modified-2-stage-method-for-auricular-reconstruction
#3
Tengxiao Ma, Feng Xie, Zhengwen Zhang
BACKGROUND: Auricular reconstruction is one of the most challenging procedures in the field of plastic surgery. The aims of this study were to apply the modified 2-stage method to perform auricular reconstruction and to summarize the clinical experience in the past 10 years. METHODS: Auricular reconstruction was performed in 243 patients (total 254 ears) of congenital microtia using autologous costal cartilage. The whole procedure is divided into 2 stages. Stage I: the individualized framework fabricated with autologous costal cartilage is inserted into subcutaneous pocket in the mastoid region, and then the earlobe was transposed backward to connect with the lower part of the framework...
June 2018: Annals of Plastic Surgery
https://www.readbyqxmd.com/read/29621075/comparison-of-incidence-and-severity-of-chronic-postsurgical-pain-following-ear-surgery
#4
Mehmet Güven, Ahmet Kara, Mahmut Sinan Yilmaz, Deniz Demir, Ebru Mihriban Güven
OBJECTIVES: Literature review shows a limited number of studies investigating chronic pain following ear surgeries. The effect of mastoidectomy on chronic postsurgical pain, however, has never been investigated. The present study investigates not only the incidence and severity of chronic pain following ear surgeries with and without mastoidectomy, but also predisposing diseases for pain. PATIENTS AND METHODS: The study was performed in a total of 150 patients who underwent tympanoplasty or tympanomastoidectomy through a retroauricular incision in a single tertiary health care center...
April 4, 2018: Journal of Craniofacial Surgery
https://www.readbyqxmd.com/read/29603603/the-retroauricular-subcutaneously-pedicled-island-flap-for-reconstruction-of-auricular-conchal-defects
#5
Christiane Motsch, Jens Ulrich
No abstract text is available yet for this article.
March 30, 2018: Journal der Deutschen Dermatologischen Gesellschaft, Journal of the German Society of Dermatology: JDDG
https://www.readbyqxmd.com/read/29559833/downregulation-of-mir-203a-disinhibits-bmi1-and-promotes-growth-and-proliferation-of-keratinocytes-in-cholesteatoma
#6
Jian Zang, Lian Hui, Ning Yang, Bo Yang, Xuejun Jiang
Background: Keratinocytes are the predominant cell type in a cholesteatoma, and microRNA (miR)-203a has been shown to be essential for the growth and differentiation of keratinocytes. The regulatory mechanisms of miR-203a and Bmi1-the predicted target of miR-203a that is associated with cholesteatoma-have not been clarified. Methods: Real-time PCR and western blot were carried out for the detection of miRNAs, mRNAs, and proteins, including miR-203a, Bmi1, and phosphorylated (p-)Akt. Immunohistochemical staining was applied to observe the expression and distribution of Bmi1 and of p-Akt in cholesteatoma and in control retroauricular skin...
2018: International Journal of Medical Sciences
https://www.readbyqxmd.com/read/29543523/evaluation-of-changes-in-skin-biophysical-parameters-and-appearance-after-pneumatic-injections-of-non-cross-linked-hyaluronic-acid-in-the-face
#7
Hai-Yan Cheng, Yu-Xin Chen, Mei-Fang Wang, Jun-Ying Zhao, Lin-Feng Li
BACKGROUND: Pneumatic injections of non-cross-linked hyaluronic acid are effective in skin rejuvenation, however, the associated biophysical parameters and appearance have not been evaluated. OBJECTIVES: To determine the changes in skin biophysical parameters after facial pneumatic injections of non-cross-linked hyaluronic acid. PATIENTS AND METHODS: Twenty-eight healthy female volunteers received pneumatic injections of non-cross-linked hyaluronic acid into the face for consecutive 5 weeks...
March 15, 2018: Journal of Cosmetic and Laser Therapy: Official Publication of the European Society for Laser Dermatology
https://www.readbyqxmd.com/read/29542884/ovarian-tissue-vitrification-and-heterotopic-autologous-transplantation-in-prepubertal-wistar-rats
#8
Leticia Wietcovsky, David Til, Rafael Alonso Salvador, Nicole Louise Lângaro Amaral, Alfred Paul Senn, Vera Lucia Lângaro Amaral
OBJECTIVE: To evaluate the efficiency of ovarian tissue heterotopic autografting after vitrification in prepubertal rats. METHODS: Fragments of excised ovaries from prepubertal rats were used after assessing post-warming cellular viability, to determine the best vitrification protocol prior to retroauricular autografting. Pre-pubertal females (N=24) were castrated and divided into three group: Group 1 - fresh ovarian tissue transplantation; Group 2 - vitrified/warmed tissue transplantation; Group 3 - bilateral oophorectomy without transplantation...
March 15, 2018: JBRA Assisted Reproduction
https://www.readbyqxmd.com/read/29473196/cd30-positive-primary-cutaneous-anaplastic-large-cell-lymphoma-with-coexistent-pseudocarcinomatous-hyperplasia
#9
A Kreuter, I Pantelaki, A-L Michalowitz, U Wieland, L Cerroni, F Oellig, C Tigges
CD30-positive primary cutaneous anaplastic large cell lymphoma (C-ALCL) is an indolent type of cutaneous lymphoma with favourable clinical prognosis. Pseudocarcinomatous hyperplasia (PCH) is a rare benign epithelial condition that can resemble invasive squamous cell carcinoma both clinically and histopathologically. PCH predominantly occurs in CD30-positive lymphoproliferative disorders. We report a 75-year-old woman with PCH in a multifocal C-ALCL located on the scalp and right retroauricular area, which rapidly responded to treatment with psoralen ultraviolet A photochemotherapy...
February 23, 2018: Clinical and Experimental Dermatology
https://www.readbyqxmd.com/read/29470606/anatomical-and-histological-evaluation-of-the-retroauricular-fascia-flap-for-staged-auricular-reconstruction
#10
Yiyuan Li, Chunxiao Cui, Ruhong Zhang, Qun Zhang, Zhicheng Xu, Feng Xu, Datao Li
OBJECTIVES: The retroauricular fascia flap (RFF) is one of the most commonly used vascularized linings for auriculocephalic sulcus reconstruction in staged total auricular reconstruction. This study aims to investigate the histomorphometric features regarding the retroauricular fascia. METHODS: Histological evaluation included qualitative observation and quantitative analysis of sections of RFF stained with hematoxylin and eosin, Masson's trichrome, Elastica van Gieson, CD31, and Lyve-1...
June 2018: Aesthetic Plastic Surgery
https://www.readbyqxmd.com/read/29462752/a-rare-case-report-of-a-typical-variant-ossifying-fibromyxoid-tumor-ofmt-located-in-the-retroauricular-perimastoid-region
#11
Theodoros Varakliotis, Gianluca Bellocchi, Alberto Eibenstein, Gilberto Acquaviva, Francesco Casorati
INTRODUCTION: Ossifying fibromixoid tumor of soft parts (OFMT) is a rare soft tissue and bone tumor. In its classic form, is considered benign, nevertheless aggressive clinical behaviour tumors with a different cytoarchitectural features of a malignant variant, have been described.The classification contains "typical", "atypical" and "malignant" variants. METHODS: A CT ear scan without contrast enhancement was carried out (October 2015), with coronal, sagittal and 3D reconstructions...
2018: International Journal of Surgery Case Reports
https://www.readbyqxmd.com/read/29419592/refinements-in-elevation-of-the-reconstructed-auricle-the-zigzag-incision
#12
So-Eun Han, Yeseul Eom, Kap Sung Oh
OBJECTIVE: Auricular elevation with superficial temporal fascia and skin graft is widely used in microtia reconstruction using costal cartilage. However, in some patients, there has been occurrence of contraction of skin graft, which led to insufficient projection of the elevated auricle and diminished auriculocephalic angle with unfavorable long-term results. In this article, the authors introduce their multiple triangular flaps with zigzag incision to maintain stable projection and natural retroauricular sulcus appearance in auricular reconstruction patients...
February 6, 2018: Journal of Craniofacial Surgery
https://www.readbyqxmd.com/read/29377557/superiorly-curved-scalp-incision-for-implantation-of-magnetic-transcutaneous-bone-conduction-devices-multicentre-experience-of-60-patients
#13
LETTER
K S Orhan, J Ray, B Polat, S Carr, N Enver, J M Deleito, L Greenwood, Y Güldiken
No abstract text is available yet for this article.
January 27, 2018: Clinical Otolaryngology
https://www.readbyqxmd.com/read/29360096/simultaneous-contralateral-vestibular-schwannoma-and-middle-ear-paraganglioma-tumor
#14
Edoardo Covelli, Guido Trasimeni, Chiara Filippi, Valerio Fabiani, Simonetta Monini, Luigi Volpini, Maurizio Barbara
To the best of our knowledge, only 2 cases of a simultaneous contralateral vestibular schwannoma (VS) and middle ear paraganglioma (MEP) have previously been reported in literature. We report the third case observed in a 43-year-old male, who presented with an 11-year history of right-sided hearing loss and a 1-year history of left-sided pulsatile tinnitus. A magnetic resonance imaging (MRI) showed a VS on the right side and computer tomography (CT) identified a Fisch type A1 paraganglioma on the left side...
December 2017: Journal of International Advanced Otology
https://www.readbyqxmd.com/read/29359346/aesthetic-reconstruction-of-retroauricular-keloid-creating-a-keystone-flap-from-the-mastoid-helix-area
#15
Tae Hwan Park, Chan Woo Kim, Choong Hyun Chang
Advances in aesthetic rhinoplasty using conchal cartilage grafts have led to a high occurrence of retroauricular keloids. The purpose of this study is to introduce our surgical experiences using a keystone flap in retroauricular keloids following conchal cartilage grafts. The present study is a retrospective review of patients with pathologically confirmed retroauricular keloids following conchal cartilage grafts. These cases were surgically excised and we covered the defect with a keystone flap followed by one-time steroid injection at postoperative day 14 and silicone gel sheeting application for 3 months...
January 23, 2018: Journal of Dermatology
https://www.readbyqxmd.com/read/29356204/robotic-surgery-for-submandibular-gland-resection-through-a-trans-hairline-approach-the-first-human-series-and-comparison-with-applicable-approaches
#16
Tsung-Lin Yang
BACKGROUND: Many submandibular gland diseases are treated by surgical intervention. Transcervical surgery results in an obvious cervical scar, whereas the retroauricular approach leaves a scar in the postauricular area. Therefore, robotic submandibular gland resection through a trans-hairline approach is developed to improve postoperative aesthetic outcomes. METHODS: From 2012 to 2017, 24 consecutive patients who met the inclusion criteria and had received submandibular gland resection through the trans-hairline robotic surgery were analyzed...
April 2018: Head & Neck
https://www.readbyqxmd.com/read/29340257/symmetrical-drug-related-intertriginous-and-flexural-exanthema-induced-by-doxycycline
#17
David G Li, Cristina Thomas, Gil S Weintraub, Arash Mostaghimi
Symmetrical drug-related intertriginous and flexural exanthema (SDRIFE) is a cutaneous drug reaction characterized by erythema over the buttocks, thighs, groin, and flexural regions most commonly associated with the use of beta-lactam antibiotics. Although the exact pathophysiology of this disease remains unknown, it is theorized to be the result of a delayed hypersensitivity response presenting as a cutaneous eruption days to weeks after exposure to the drug. The treatment involves discontinuation of the suspected medication, symptomatic control of pruritus, and topical steroid therapy...
November 10, 2017: Curēus
https://www.readbyqxmd.com/read/29339001/does-the-surgical-approach-for-treating-mandibular-condylar-fractures-affect-the-rate-of-seventh-cranial-nerve-injuries-a-systematic-review-and-meta-analysis-based-on-a-new-classification-for-surgical-approaches
#18
Essam Ahmed Al-Moraissi, Aurélien Louvrier, Giacomo Colletti, Larry M Wolford, Federico Biglioli, Marwa Ragaey, Christophe Meyer, Edward Ellis
PURPOSE: The purpose of this study was to determine the rate of facial nerve injury (FNI) when performing (ORIF) of mandibular condylar fractures by different surgical approaches. MATERIALS AND METHODS: A systematic review and meta-analysis were performed that included several databases with specific keywords, a reference search, and a manual search for suitable articles. The inclusion criteria were all clinical trials, with the aim of assessing the rate of facial nerve injuries when (ORIF) of mandibular condylar fractures was performed using different surgical approaches...
March 2018: Journal of Cranio-maxillo-facial Surgery
https://www.readbyqxmd.com/read/29277981/a-protective-role-for-fadd-dominant-negative-fadd-dn-mutant-in-trinitrochlorobenzene-tncb-induced-murine-contact-hypersensitivity-reactions
#19
X Zhang, Y Han, L Song, L Huo, X Lai, Y Zhang, J Zhang, Z Hua
BACKGROUND: Fas-associated protein with death domain (FADD) is a classic adaptor protein in apoptosis. Increasing evidence has shown that FADD is also implicated in T-cell development, activation and proliferation. The role of FADD in inflammatory disorders remains largely unexplored. AIM: To assess the role of FADD in inflammatory disorders. METHODS: We established an experimental model of contact hypersensitivity (CHS) by using 2,4,6-trinitrochlorobenzene (TNCB) on transgenic mice expressing a dominant negative mutant of FADD (FADD-DN), RESULTS: CHS responses were clearly attenuated in FADD-DN mice compared with control mice...
December 26, 2017: Clinical and Experimental Dermatology
https://www.readbyqxmd.com/read/29262448/-application-of-functional-parotidectomy-via-retroauricular-hairline-incision-in-the-excising-superficial-parotid-tumor
#20
P A Wu, Z Q Lu, Y F Guan, H L Zhu, X N Liang, W Y Liang, R K Tsang
Objective: To evaluate the usefulness of retroauricular hairline incision (RAHI) in partial superficial parotidectomy (PSP) by comparison with modified Blair incision (MBI). Methods: A retrospective analysis of 64 medical records for patients with benign parotid tumors who underwent partial superficial parotidectomy was undertaken (28 were in MBI group, 36 in RAHI group). Size and location of tumors, operative time, occurrence of facial nerve paralysis and Frey's syndrome, and cosmetic outcomes were compared between RAHI and MBI groups...
December 7, 2017: Zhonghua Er Bi Yan Hou Tou Jing Wai Ke za Zhi, Chinese Journal of Otorhinolaryngology Head and Neck Surgery
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