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https://www.readbyqxmd.com/read/28817569/long-term-assessment-of-whale-shark-population-demography-and-connectivity-using-photo-identification-in-the-western-atlantic-ocean
#1
Jennifer A McKinney, Eric R Hoffmayer, Jason Holmberg, Rachel T Graham, William B Driggers, Rafael de la Parra-Venegas, Beatriz E Galván-Pastoriza, Steve Fox, Simon J Pierce, Alistair D M Dove
The predictable occurrence of whale sharks, Rhincodon typus, has been well documented in several areas. However, information relating to their migratory patterns, residency times and connectivity across broad spatial scales is limited. In the present study photo-identification data is used to describe whale shark population structure and connectivity among known aggregation sites within the Western Central Atlantic Ocean (WCA). From 1999 to 2015, 1,361 individuals were identified from four distinct areas: the Yucatan Peninsula, Mexico (n = 1,115); Honduras (n = 146); northern Gulf of Mexico, United States (n = 112), and Belize (n = 49)...
2017: PloS One
https://www.readbyqxmd.com/read/28814621/endothelial-cell-function-and-dysfunction-in-critically-ill-children
#2
REVIEW
Richard W Pierce, John S Giuliano, Jordan S Pober
Endothelial cells (ECs) line the lumen of the entire vascular system and actively regulate blood flow; maintain blood fluidity; control water, solute, and macromolecular transfer between blood and tissue; and modulate circulating immune cell recruitment and activation. These vital functions, combined with the broad anatomic distribution of ECs, implicate them in all forms of critical illness. The present article discusses how ECs adapt and break down during the course of critical illness. We first review the biology of ECs, highlighting the vascular segmental differences and their specific roles in the maintenance of homeostasis...
June 1, 2017: Pediatrics
https://www.readbyqxmd.com/read/28811519/high-resolution-mapping-based-on-an-unmanned-aerial-vehicle-uav-to-capture-paleoseismic-offsets-along-the-altyn-tagh-fault-china
#3
Mingxing Gao, Xiwei Xu, Yann Klinger, Jerome van der Woerd, Paul Tapponnier
The recent dramatic increase in millimeter- to centimeter- resolution topographic datasets obtained via multi-view photogrammetry raises the possibility of mapping detailed offset geomorphology and constraining the spatial characteristics of active faults. Here, for the first time, we applied this new method to acquire high-resolution imagery and generate topographic data along the Altyn Tagh fault, which is located in a remote high elevation area and shows preserved ancient earthquake surface ruptures. A digital elevation model (DEM) with a resolution of 0...
August 15, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28810929/the-impact-of-age-and-gut-microbiota-on-th17-and-tfh-cells-in-k-bxn-autoimmune-arthritis
#4
Fei Teng, Krysta M Felix, C Pierce Bradley, Debdut Naskar, Heqing Ma, Walid A Raslan, Hsin-Jung Joyce Wu
BACKGROUND: Age is an important risk factor for rheumatoid arthritis (RA), which often develops in middle age. However, how age-associated changes in immunity impact RA is poorly understood. Gut microbiota are known to be involved in the pathogenesis of RA, but the effects of microbiota in older subjects remain mostly unknown. METHODS: We used segmented filamentous bacteria (SFB), a gut commensal species with immunomodulatory effects, and K/BxN mice, a T cell receptor (TCR) transgenic model, to study the effect of age and microbiota on autoimmune arthritis...
August 15, 2017: Arthritis Research & Therapy
https://www.readbyqxmd.com/read/28808757/ct-guided-percutaneous-trans-scapular-lung-biopsy-in-the-diagnosis-of-peripheral-pulmonary-lesion-nodules-of-the-superior-lobes-using-large-needles
#5
Alberto Rebonato, Daniele Maiettini, Marco Andolfi, Matthias J Fischer, Jacopo Vannucci, Giulio Metro, Antonio Basile, Michele Rossi, Michele Duranti
PURPOSE: CT-guided percutaneous transthoracic lung needle biopsy (PLB) is an effective procedure for obtaining cyto-histological diagnoses of peripheral lesions. However, upper postero-lateral lung nodules (UPLN) may be difficult to reach using a standard intercostal either anterior or lateral approach or when the nodule is just behind a rib or scapula. We evaluated the feasibility and effectiveness of trans-scapular approach (tPLB) in these patients using large-core needles. METHODS: We retrospectively collected the data of 11 consecutive patients (mean age 74...
August 14, 2017: Cardiovascular and Interventional Radiology
https://www.readbyqxmd.com/read/28808087/the-drosophila-lc8-homologue-cut-up-specifies-the-axonal-transport-of-proteasomes
#6
Tabita Kreko-Pierce, Benjamin A Eaton
Because of their functional polarity and elongated morphologies, microtubule-based transport of proteins and organelles is critical for normal neuronal function. The proteasome is required throughout the neuron for the highly regulated degradation of a broad set of protein targets whose functions underlie key physiological responses including synaptic plasticity and axonal degeneration. Molecularly, the relationship between proteasome transport and the transport of the targets of proteasomes is unclear. The dynein motor complex is required for the microtubule-based motility of numerous proteins and organelles in neurons...
August 14, 2017: Journal of Cell Science
https://www.readbyqxmd.com/read/28807388/building-a-hospital-core-resource-for-clinical-research-imaging-lessons-for-driving-change-within-complex-organizations
#7
Richard G Abramson, Carrie R McGhee, Susan M Meyn, Kim Coleman, John Gomillion, Marc Beller, Janet Fry, Gail A Bauer, Ronald J Knuutila, Richard Pierce, James A Patton, Reed A Omary
No abstract text is available yet for this article.
August 11, 2017: Journal of the American College of Radiology: JACR
https://www.readbyqxmd.com/read/28806494/body-piercing-motivations-and-implications-for-health
#8
REVIEW
Cheri Van Hoover, Carol-Ann Rademayer, Cindy L Farley
Body piercing has evolved from a behavior once considered extreme to an accepted choice among the general population. Earlobe piercing is so common that it is now considered a normative behavior. The motivations for choosing body piercing have changed and are associated with piercing site and number of piercings chosen by the individual. Meanings ascribed to body piercing were traditionally related to enhanced sexual desirability and experience, but now range from the innocuous, such as a fashion statement, to the risk laden, such as nonsuicidal self-injury...
August 14, 2017: Journal of Midwifery & Women's Health
https://www.readbyqxmd.com/read/28806128/exploring-the-motivations-for-body-piercing-a-pilot-study
#9
Andrew Crowther, Rachel Kornhaber, Fredrik Velander, Sally Drummond, Michelle Cleary
No abstract text is available yet for this article.
August 2017: Issues in Mental Health Nursing
https://www.readbyqxmd.com/read/28806071/contrasting-effects-of-dissolved-organic-matter-on-mercury-methylation-by-g-sulfurreducens-pca-and-d-desulfuricans-nd132
#10
Linduo Zhao, Hongmei Chen, Xia Lu, Hui Lin, Geoff A Christensen, Eric M Pierce, Baohua Gu
Natural dissolved organic matter (DOM) affects mercury (Hg) redox reactions and anaerobic microbial Hg methylation in the environment. Several studies have shown that DOM can enhance Hg methylation, especially under sulfidic conditions, whereas others show that DOM inhibits Hg methylation due to strong Hg-DOM complexation. In this study, we investigated and compared the effects of DOM on Hg methylation by an iron-reducing bacterium Geobacter sulfurreducens PCA and a sulfate-reducing bacterium Desulfovibrio desulfuricans ND132 under non-sulfidic conditions...
August 14, 2017: Environmental Science & Technology
https://www.readbyqxmd.com/read/28804644/a-malaria-vaccine-protects-aotus-monkeys-against-virulent-plasmodium-falciparum-infection
#11
Prakash Srinivasan, G Christian Baldeviano, Kazutoyo Miura, Ababacar Diouf, Julio A Ventocilla, Karina P Leiva, Luis Lugo-Roman, Carmen Lucas, Sachy Orr-Gonzalez, Daming Zhu, Eileen Villasante, Lorraine Soisson, David L Narum, Susan K Pierce, Carole A Long, Carter Diggs, Patrick E Duffy, Andres G Lescano, Louis H Miller
The Plasmodium falciparum protein, apical membrane antigen 1 forms a complex with another parasite protein, rhoptry neck protein 2, to initiate junction formation with the erythrocyte and is essential for merozoite invasion during the blood stage of infection. Consequently, apical membrane antigen 1 has been a target of vaccine development but vaccination with apical membrane antigen 1 alone in controlled human malaria infections failed to protect and showed limited efficacy in field trials. Here we show that vaccination with AMA1-RON2L complex in Freund's adjuvant protects Aotus monkeys against a virulent Plasmodium falciparum infection...
2017: NPJ Vaccines
https://www.readbyqxmd.com/read/28803559/rethinking-the-idea-of-late-autism-spectrum-disorder-onset
#12
Elizabeth C Bacon, Eric Courchesne, Cynthia Carter Barnes, Debra Cha, Sunny Pence, Laura Schreibman, Aubyn C Stahmer, Karen Pierce
A common theory of autism spectrum disorder (ASD) symptom onset includes toddlers who do not display symptoms until well after age 2, which are termed late-onset ASD cases. Objectives were to analyze differences in clinical phenotype between toddlers identified as ASD at initial evaluations (early diagnosed) versus those initially considered nonspectrum, then later identified as ASD (late diagnosed). Two hundred seventy-three toddlers recruited from the general population based on a failed developmental screening form or parent or physician concerns were followed longitudinally from 12 months and identified as early- and late-diagnosed cases of ASD, language delayed, or typically developing...
August 14, 2017: Development and Psychopathology
https://www.readbyqxmd.com/read/28801524/muscle-contraction-induced-arterial-shear-stress-increases-endothelial-nitric-oxide-synthase-phosphorylation-in-humans
#13
Darren P Casey, Kenichi Ueda, Lauren J Wegman-Points, Gary L Pierce
We determined if local increases in brachial artery shear during repetitive muscle contractions induce changes in protein expression of endothelial nitric oxide synthase (eNOS) and/or phosphorylated eNOS at serine 1177 (P-eNOS(ser1177)), the primary activation site on eNOS, in endothelial cells (ECs) of humans. Seven young males (25±1 yr) performed 20 separate bouts (3 min each) of rhythmic forearm exercise at 20% of max over a 2-hr period. Each bout of exercise was separated by 3 min of rest. An additional six male subjects (24±1 yr) served as time controls (no exercise)...
August 11, 2017: American Journal of Physiology. Heart and Circulatory Physiology
https://www.readbyqxmd.com/read/28801523/dietary-modulation-of-oxylipins-in-cardiovascular-disease-and-aging
#14
Stephanie P B Caligiuri, Mihir Parikh, Aleksandra Stamenkovic, Grant N Pierce, Harold M Aukema
Oxylipins are a group of fatty acid metabolites generated via oxygenation of polyunsaturated fatty acids and are involved in processes such as inflammation, immunity, pain, vascular tone and coagulation. As a result, oxylipins are implicated in many conditions characterized by these processes including cardiovascular disease and aging. The best characterized oxylipins in relation to cardiovascular disease are derived from the ω-6 fatty acid arachidonic acid. These oxylipins generally increase inflammation, hypertension and platelet aggregation, although not universally...
August 11, 2017: American Journal of Physiology. Heart and Circulatory Physiology
https://www.readbyqxmd.com/read/28800768/3d-printing-assisted-preoperative-plan-of-pedicle-screw-placement-for-middle-upper-thoracic-trauma-a-cohort-study
#15
Wei Xu, Xuming Zhang, Tie Ke, Hongru Cai, Xiang Gao
BACKGROUND: This study aimed to evaluate the application of 3D printing in assisting preoperative plan of pedicle screw placement for treating middle-upper thoracic trauma. METHODS: A preoperative plan was implemented in seven patients suffering from middle-upper thoracic (T3-T7) trauma between March 2013 and February 2016. In the 3D printing models, entry points of 56 pedicle screws (Magerl method) and 4 important parameters of the pedicle screws were measured, including optimal diameter (ϕ, mm), length (L, mm), inclined angle (α), head-tilting angle (+β), and tail-tilting angle (-β)...
August 11, 2017: BMC Musculoskeletal Disorders
https://www.readbyqxmd.com/read/28799198/does-paying-service-providers-by-results-improve-recovery-outcomes-for-drug-misusers-in-treatment-in-england
#16
Andrew Jones, Matthias Pierce, Matt Sutton, Thomas Mason, Tim Millar
AIM: To compare drug recovery outcomes in commissioning areas included in a 'payment by results' scheme with all other areas. DESIGN: Observational and data linkage study of the National Drug Treatment Monitoring System, Office for National Statistics mortality database, and Police National Computer criminal records, for two years before and after introduction of the scheme. Pre-post controlled comparison compared outcomes in participating versus non-participating areas following adjustment for drug use, functioning and drug treatment status...
August 10, 2017: Addiction
https://www.readbyqxmd.com/read/28798541/animal-assisted-therapies-for-youth-with-or-at-risk-for-mental-health-problems-a-systematic-review
#17
Kimberly Eaton Hoagwood, Mary Acri, Meghan Morrissey, Robin Peth-Pierce
To systematically review experimental evidence about animal-assisted therapies (AAT) for children or adolescents with or at risk for mental health conditions, we reviewed all experimental AAT studies published between 2000-2015, and compared studies by animal type, intervention, and outcomes. METHODS: Studies were included if used therapeutically for children and adolescents (≤21 years) with or at risk for a mental health problem; used random assignment or a waitlist comparison/control group; and included child-specific outcome data...
2017: Applied Developmental Science
https://www.readbyqxmd.com/read/28795087/dataset-on-psychosocial-risk-factors-in-cases-of-fatal-and-near-fatal-physical-child-abuse
#18
Mary Clyde Pierce, Kim Kaczor, Deborah Acker, Tina Webb, Allen Brenzel, Douglas J Lorenz, Audrey Young, Richard Thompson
This article presents the psychosocial risk factors identified in the cases of 20 children less than four years of age who were victims of fatal or near-fatal physical abuse during a 12 month period in the Commonwealth of Kentucky. These data are related to the article "History, injury, and psychosocial risk factor commonalities among cases of fatal and near-fatal physical child abuse" (Pierce et al., 2017) [1].
October 2017: Data in Brief
https://www.readbyqxmd.com/read/28794575/caregiver-decision-making-household-response-to-child-illness-in-sub-saharan-africa
#19
Hayley Pierce, Ashley Larsen Gibby, Renata Forste
We draw upon a framework outlining household recognition and response to child illness proposed by Colvin and colleagues (2013) to examine factors predictive of treatment sought for a recent child illness. In particular, we model whether no treatment, middle layer treatment (traditional healer, pharmacy, community health worker, etc.), or biomedical treatment was sought for recent episodes of diarrhea, fever, or cough. Based on multinomial, multilevel analyses of Demographic and Health Surveys from 19 countries in sub-Saharan Africa, we determine that if women have no say in their own healthcare, they are unlikely to seek treatment in response to child illness...
October 2016: Population Research and Policy Review
https://www.readbyqxmd.com/read/28794021/structure-based-design-of-hepatitis-c-virus-vaccines-that-elicit-neutralizing-antibody-responses-to-a-conserved-epitope
#20
Brian G Pierce, Elisabeth N Boucher, Kurt H Piepenbrink, Monir Ejemel, Chelsea A Rapp, William D Thomas, Eric J Sundberg, Zhiping Weng, Yang Wang
Despite recent advances in therapeutic options, hepatitis C virus (HCV) remains a severe global disease burden, and a vaccine can substantially reduce its incidence. Due to its extremely high sequence variability, HCV can readily escape the immune response, thus an effective vaccine must target conserved, functionally important epitopes. Using the structure of a broadly neutralizing antibody in complex with a conserved linear epitope from the HCV E2 envelope glycoprotein (residues 412-423; epitope I), we performed structure-based design of immunogens to induce antibody responses to this epitope...
August 9, 2017: Journal of Virology
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