Hidayat Ullah, Ting Deng, Muhsin Ali, Nabeel Ahmed Farooqui, Duaa M Alsholi, Nimra Zafar Siddiqui, Ata Ur Rehman, Sharafat Ali, Muhammad Ilyas, Liang Wang, Yi Xin
Inflammatory bowel disease (IBD) is a persistent, lifelong inflammation of the digestive system. Dextran sulfate sodium is commonly used to induce colitis in experimental animal models, which causes epithelial damage, intestinal inflammation, mucin depletion, and dysbiosis of the gut microbiota. Various prebiotics, polysaccharides, and polypeptides are used for IBD treatment. In this study, we used a murine model utilizing BALB/c mice, with 10 mice per group, to investigate the treatment effect of sea conch peptide hydrolysate (CPH) on DSS-induced colitis mice...
September 28, 2023: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry