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https://www.readbyqxmd.com/read/28421191/prospective-multicentre-study-on-the-epidemiology-and-current-therapeutic-management-of-severe-bronchiolitis-in-spain
#1
Jose C Flores-González, Juan Mayordomo-Colunga, Iolanda Jordan, Alicia Miras-Veiga, Cristina Montero-Valladares, Marta Olmedilla-Jodar, Andrés J Alcaraz-Romero, Miren Eizmendi-Bereciartua, Francisco Fernández-Carrión, Carmen Santiago-Gutierrez, Esther Aleo-Luján, Sonia Pérez-Quesada, Cristina Yun-Castilla, Carmen Martín, Álvaro Navarro-Mingorance, Concha Goñi-Orayen
Objective. To determine the epidemiology and therapeutic management of patients with severe acute bronchiolitis (AB) admitted to paediatric intensive care units (PICUs) in Spain. Design. Descriptive, prospective, multicentre study. Setting. Sixteen Spanish PICUs. Patients. Patients with severe AB who required admission to any of the participating PICUs over 1 year. Interventions. Both epidemiological variables and medical treatment received were recorded. Results. A total of 262 patients were recruited; 143 were male (54...
2017: BioMed Research International
https://www.readbyqxmd.com/read/28415781/relevance-of-dna-repair-gene-polymorphisms-to-gastric-cancer-risk-and-phenotype
#2
Patricia Carrera-Lasfuentes, Angel Lanas, Luis Bujanda, Mark Strunk, Enrique Quintero, Santos Santolaria, Rafael Benito, Federico Sopeña, Elena Piazuelo, Concha Thomson, Angeles Pérez-Aisa, David Nicolás-Pérez, Elizabeth Hijona, Jesús Espinel, Rafael Campo, Marisa Manzano, Fernando Geijo, María Pellise, Manuel Zaballa, Ferrán González-Huix, Jorge Espinós, Llúcia Titó, Luis Barranco, Mauro D'Amato, María Asunción García-González
Variations in DNA repair genes have been reported as key factors in gastric cancer (GC) susceptibility but results among studies are inconsistent. We aimed to assess the relevance of DNA repair gene polymorphisms and environmental factors to GC risk and phenotype in a Caucasian population in Spain. Genomic DNA from 603 patients with primary GC and 603 healthy controls was typed for 123 single nucleotide polymorphisms in DNA repair genes using the Illumina platform. Helicobacter pylori infection with CagA strains (odds ratio (OR): 1...
March 16, 2017: Oncotarget
https://www.readbyqxmd.com/read/28401248/-nasal-turbinate-surgery
#3
F Sommer, J Lindemann, M-O Scheithauer, T K Hoffmann, J A Veit
The nose forms the first 8 cm of the upper respiratory tract and is responsible for cleansing, humidification, and temperature control of the supplied air. This is also referred to as conditioning. The nasal valve region, formed by the head of the lower nasal concha, portions of the cartilaginous septum, and the upper lateral cartilage, is responsible for diffusing and accelerating the respiratory airflow. Prerequisite are regular mucociliary clearance and sufficient air passage. Hypertrophy of the lower nasal turbinate is one of the most common causes of symptomatic nasal congestion...
April 11, 2017: HNO
https://www.readbyqxmd.com/read/28400825/association-of-anatomic-variations-with-antrochoanal-polyps-in-paranasal-sinus-computed-tomography-scan
#4
Ali Hekmatnia, Farid Shirvani, Farhad Mahmoodi, Mostafa Hashemi
BACKGROUND: This study was designed to determine the prevalence of concomitant anatomic variation of paranasal sinuses in patients with antrochoanal polyp (ACP). MATERIALS AND METHODS: Among patients referred by their clinicians for standard computed tomography scan of paranasal sinuses septal deviation, concha bullosa, and retention cyst were evaluated in both patients with ACP as well as in a control group. RESULTS: Of the 17 patients with ACP, fifteen patients (88...
2017: Journal of Research in Medical Sciences: the Official Journal of Isfahan University of Medical Sciences
https://www.readbyqxmd.com/read/28396871/innervation-of-the-human-cavum-conchae-and-auditory-canal-anatomical-basis-for-transcutaneous-auricular-nerve-stimulation
#5
P Bermejo, M López, I Larraya, J Chamorro, J L Cobo, S Ordóñez, J A Vega
The innocuous transcutaneous stimulation of nerves supplying the outer ear has been demonstrated to be as effective as the invasive direct stimulation of the vagus nerve for the treatment of some neurological and nonneurological disturbances. Thus, the precise knowledge of external ear innervation is of maximal interest for the design of transcutaneous auricular nerve stimulation devices. We analyzed eleven outer ears, and the innervation was assessed by Masson's trichrome staining, immunohistochemistry, or immunofluorescence (neurofilaments, S100 protein, and myelin-basic protein)...
2017: BioMed Research International
https://www.readbyqxmd.com/read/28393987/-validation-of-self-applicable-questionnaire-for-a-mediterranean-dietary-index-in-chile
#6
Guadalupe Echeverría, Inés Urquiaga, María José Concha, Catalina Dussaillant, Luis Villarroel, Nicolás Velasco, Federico Leighton, Attilio Rigotti
BACKGROUND: Availability of brief dietary indexes that can effectively evaluate dietary patterns and their association with health is critical for prevention and management of several chronic disease conditions. AIM: To adapt a self-applicable Mediterranean Dietary Index in Chile (Chilean-MDI). MATERIAL AND METHODS: The Chilean-MDI was developed based on a previous Mediterranean eating score that was adapted to Chilean dietary habits. This index was further validated in a sample of 153 adults by comparing the concordance between the results obtained by self-application of the Chilean-MDI with those obtained by a trained nutritionist...
December 2016: Revista Médica de Chile
https://www.readbyqxmd.com/read/28377175/tactile-object-categories-can-be-decoded-from-the-parietal-and-lateral-occipital-cortices
#7
Raúl Hernández-Pérez, Laura V Cuaya, Eduardo Rojas-Hortelano, Azalea Reyes-Aguilar, Luis Concha, Victor de Lafuente
The visual system classifies objects into categories, and distinct populations of neurons within the temporal lobe respond preferentially to objects of a given perceptual category. We can also classify the objects we recognize with the sense of touch, but less is known about the neuronal correlates underlying this cognitive function. To address this question, we performed a multivariate pattern analysis (MVPA) of functional magnetic resonance imagining (fMRI) activity to identify the cortical areas that can be used to decode the category of objects explored with the hand...
April 2, 2017: Neuroscience
https://www.readbyqxmd.com/read/28367779/regional-solar-radiation-is-inversely-correlated-with-incidence-and-severity-of-tuberculosis-in-chile
#8
M E Balcells, J Cerda, S Concha, R Hoyos-Bachiloglu, C A Camargo, A R Martineau, A Borzutzky
Vitamin D (VD) deficiency has been linked to increased incidence and morbidity of tuberculosis (TB). Chile has large variations in solar radiation (SR; a proxy of VD status) and high prevalence of VD deficiency in its southernmost regions with low SR. We investigated the correlation between regional SR and rates of TB incidence, admissions and deaths in Chile by reviewing national records on prospectively collected mandatory disease notifications, admissions and mortality between 2001 and 2011. Over the study period, 26 691 new TB notifications were registered...
April 3, 2017: Epidemiology and Infection
https://www.readbyqxmd.com/read/28359726/migraine-a-look-down-the-nose
#9
Thomas Muehlberger, Justin C R Wormald, Nadine Hachach-Haram, Afshin Mosahebi
BACKGROUND: Studies have suggested that contact between opposing mucosal surfaces in the nasal wall and cavity can be a target of the surgical treatment of migraines. Unfortunately, not enough is known about the role of nasal pathology in the pathogenesis of this condition. The co-existence of further rhinological disorders can be an impediment to defining the cause and effect of anatomical variants. The authors compared the MRI scans of migraine- and non-migraine patients (MPs and NMPs, respectively) to determine the prevalence of such mucosal contact points in order to extrapolate whether there is a significant association with migraines...
March 7, 2017: Journal of Plastic, Reconstructive & Aesthetic Surgery: JPRAS
https://www.readbyqxmd.com/read/28355252/factors-associated-with-early-mycological-clearance-in-hiv-associated-cryptococcal-meningitis
#10
Fátima Concha-Velasco, Elsa González-Lagos, Carlos Seas, Beatriz Bustamante
INTRODUCTION: The first-line combination therapy for HIV-associated cryptococcal meningitis (CM), a condition of high mortality particularly in the first two weeks of treatment, consists of amphotericin B plus flucytosine (5-FC). Given that 5-FC remains unavailable in many countries, the knowledge of factors influencing mycological clearance in patients treated with second-line therapy could contribute to effective management. OBJECTIVES: To determine the factors associated with the clearance of Cryptococcus sp...
2017: PloS One
https://www.readbyqxmd.com/read/28349586/transfemoral-access-when-superior-venous-approach-is-not-feasible-equals-overall-success-of-permanent-pacemaker-implantation-ten-year-series
#11
Juan J García Guerrero, Joaquín Fernández de la Concha Castañeda, Manuel Doblado Calatrava, Ángel Redondo Méndez, Manuel Lázaro Medrano, Antonio Merchán Herrera
BACKGROUND: When permanent pacemaker implantation is not possible or advisable via superior venous access (i.e., axillary or subclavian veins), safe and feasible surgical alternatives are required. The femoral approach is relatively unknown and seldom studied. This single-centre study analysed 10-year outcomes of a femoral implantation approach. METHODS: Data about the implantation procedure (indication, approach, lead and pacemaker models, complications), patient characteristics (age, sex, medications, comorbidities), and follow-up were analysed for all permanent pacemaker implantations using the femoral approach between June 2001 and June 2011...
March 28, 2017: Pacing and Clinical Electrophysiology: PACE
https://www.readbyqxmd.com/read/28348652/nasal-septal-deviation-and-concha-bullosa-do-they-have-an-impact-on-maxillary-sinus-volumes-and-prevalence-of-maxillary-sinusitis
#12
Iwona Kucybała, Konrad Adam Janik, Szymon Ciuk, Dawid Storman, Andrzej Urbanik
BACKGROUND: The aim of the study was to assess if the presence of nasal septal deviation and concha bullosa is connected with the development of sinuses and the incidence of inflammation within them. MATERIAL/METHODS: We retrospectively analysed 214 patients who underwent paranasal sinus computed tomography. There were 125 females and 89 males, the mean age being 47.67±16.74 years (range 18-97). Exclusion criteria included: age under 18 years, prior sinonasal surgery and S-shaped septum...
2017: Polish Journal of Radiology
https://www.readbyqxmd.com/read/28342739/supervised-physical-therapy-vs-home-exercise-program-for-patients-with-distal-radius-fracture-a-single-blind-randomized-clinical-study
#13
Héctor Gutiérrez-Espinoza, David Rubio-Oyarzún, Cristian Olguín-Huerta, Rodrigo Gutiérrez-Monclus, Sebastian Pinto-Concha, Gonzalo Gana-Hervias
STUDY DESIGN: Randomized clinical study. INTRODUCTION: Supervised physical therapy (PT) and home exercise programs (HEPs) are frequently used in the rehabilitation of patients with distal radius fracture (DRF). However, there is no consensus as to whether unsupervised HEP provides comparable benefits to those achieved by supervised PT. PURPOSE OF THE STUDY: To compare the improvements in pain and functional status between a supervised PT program and unsupervised HEP in DRF patients older than 60 years...
March 22, 2017: Journal of Hand Therapy: Official Journal of the American Society of Hand Therapists
https://www.readbyqxmd.com/read/28339693/neuronal-signaling-repertoire-in-the-mammalian-sperm-functionality
#14
Alfredo Ramírez-Reveco, Franz Villarroel-Espíndola, Joan E Rodríguez-Gil, Ilona I Concha
The common embryonic origin has been a recurrent explanation to understand the presence of "neural receptors" in sperm. However, this designation has conditioned a bias marked by the classical neurotransmission model, dismissing the possibility that neurotransmitters can play specific roles in the sperm function by themselves. For instance, the launching of acrosome reaction, a fundamental sperm function, includes several steps that recall the process of presynaptic secretion. Unlike of postsynaptic neuron, whose activation is mediated by molecular interaction between neurotransmitter and postsynaptic receptors, the oocyte activation is not mediated by receptors, but by cytosolic translocation of sperm phospholipase (PLCζ)...
March 1, 2017: Biology of Reproduction
https://www.readbyqxmd.com/read/28339565/association-of-cardiac-resynchronization-therapy-with-the-incidence-of-appropriate-implantable-cardiac-defibrillator-therapies-in-ischaemic-and-non-ischaemic-cardiomyopathy
#15
Gerard Loughlin, Pablo Avila, Jose B Martinez-Ferrer, Javier Alzueta, Xavier Vinolas, Josep Brugada, Jose M Arizon, Ignacio Fernandez-Lozano, Enrique García-Campo, Nuria Basterra, Joaquin Fernandez De La Concha, Angel Arenal
Aims: Cardiac resynchronization therapy (CRT) reduces the incidence of sudden cardiac death and the use of appropriate implantable cardioverter-defibrillator (ICD) therapies (AICDTs); however, this antiarrhythmic effect is only observed in certain groups of patients. To gain insight into the effects of CRT on ventricular arrhythmia (VA) burden, we compared the incidence of AICDT use in four groups of patients: patients with ischaemic cardiomyopathy vs. non-ischaemic dilated cardiomyopathy (NIDC) and patients implanted with an ICD vs...
October 6, 2016: Europace: European Pacing, Arrhythmias, and Cardiac Electrophysiology
https://www.readbyqxmd.com/read/28333162/the-endoplasmic-reticulum-chaperone-grp78-bip-modulates-prion-propagation-in-vitro-and-in-vivo
#16
Kyung-Won Park, Gyoung Eun Kim, Rodrigo Morales, Fabio Moda, Ines Moreno-Gonzalez, Luis Concha-Marambio, Amy S Lee, Claudio Hetz, Claudio Soto
Prion diseases are fatal neurodegenerative disorders affecting several mammalian species, characterized by the accumulation of the misfolded form of the prion protein, which is followed by the induction of endoplasmic reticulum (ER) stress and the activation of the unfolded protein response (UPR). GRP78, also called BiP, is a master regulator of the UPR, reducing ER stress levels and apoptosis due to an enhancement of the cellular folding capacity. Here, we studied the role of GRP78 in prion diseases using several in vivo and in vitro approaches...
March 23, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28325622/the-effect-of-different-nasal-irrigation-solutions-following-septoplasty-and-concha-radiofrequency-a-prospective-randomized-study
#17
Hanifi Kurtaran, K Serife Ugur, Ceyda Sel Yilmaz, Mesut Kaya, Alper Yuksel, Nebil Ark, Mehmet Gunduz
INTRODUCTION: Nasal irrigation solutions are widely used following endonasal surgery. These irrigation solutions remove infective debris and crusts, reducing the probability of synechia formation, and accelerate mucosal healing. OBJECTIVE: The aim of the present study was to compare the effects of nasal irrigation solutions with different contents following septoplasty and concha radiofrequency. METHODS: The present study was a prospective, randomized, controlled simple blind study of 120 patients who underwent septoplasty and bilateral concha radiofrequency...
February 22, 2017: Brazilian Journal of Otorhinolaryngology
https://www.readbyqxmd.com/read/28319890/one-year-follow-up-of-clinical-metabolic-and-oxidative-stress-profile-of-morbid-obese-patients-after-laparoscopic-sleeve-gastrectomy-8-oxo-dg-as-a-clinical-marker
#18
Lidia Monzo-Beltran, Antonio Vazquez-Tarragón, Concha Cerdà, Paula Garcia-Perez, Antonio Iradi, Carlos Sánchez, Benjamin Climent, Carmen Tormos, Antonio Vázquez-Prado, Javier Girbés, Nuria Estáñ, Sebastián Blesa, Raquel Cortés, Felipe J Chaves, Guillermo T Sáez
Obesity has grown worldwide over the last few decades. In its different degrees, obesity is accompanied by many clinical and biochemical alterations reflecting the pathological condition of various body tissues. Among the mechanisms underlying the pathogenesis of obesity and associated complications, oxidative stress (OS) may be playing an important role. In the present study, we have characterized at systemic level the degree of OS status in a group of morbid obese patients (BMI>40kg/m(2)) at basal sate and its modulation during one year after bariatric surgery using the laparoscopic sleeve gastrectomy (LSG) technique...
February 14, 2017: Redox Biology
https://www.readbyqxmd.com/read/28300453/multiple-skin-colored-papules-on-the-auricular-concha
#19
Filiz Topaloğlu Demir, Fatma Deniz, Ilknur Kıvanc Altunay, Yalçın Ozben
No abstract text is available yet for this article.
March 2017: Journal of Cutaneous Medicine and Surgery
https://www.readbyqxmd.com/read/28275382/corrigendum-cell-wall-remodeling-in-abscission-zone-cells-during-ethylene-promoted-fruit-abscission-in-citrus
#20
Paz Merelo, Javier Agustí, Vicent Arbona, Mário L Costa, Leandro H Estornell, Aurelio Gómez-Cadenas, Silvia Coimbra, María D Gómez, Miguel A Pérez-Amador, Concha Domingo, Manuel Talón, Francisco R Tadeo
[This corrects the article on p. 126 in vol. 8, PMID: 28228766.].
2017: Frontiers in Plant Science
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