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https://www.readbyqxmd.com/read/28794961/feline-cutaneous-histoplasmosis-the-first-case-report-from-thailand
#1
L Larsuprom, L Duangkaew, C Kasorndorkbua, C Chen, A Chindamporn, N Worasilchai
A 2-year-old, neutered female domestic shorthaired cat presented with a history of multiple papules and nodules on pinnae, nodules on the nose, and chronic wound at the lateral surface of left radial area for four months. Skin biopsy demonstrated moderate numbers of small, oval-to-round, single-walled yeasts inside the macrophages. In addition, PCR confirmed the sequence of Histoplasma capsulatum. This is the first case report of feline cutaneous histoplasmosis in Thailand.
December 2017: Medical Mycology Case Reports
https://www.readbyqxmd.com/read/28770691/outbreak-of-salmonella-enteritidis-phage-type-1b-associated-with-frozen-pre-cooked-chicken-cubes-finland-2012
#2
S Huusko, A Pihlajasaari, S Salmenlinna, J Sõgel, I Dontšenko, E DE Pinna, H Lundström, S Toikkanen, R Rimhanen-Finne
In August to October 2012, a nationwide outbreak of Salmonella enteritidis phase type (PT) 1B with 53 cases occurred in Finland. Hypothesis generating interviews pointed toward ready-to-eat chicken salad from a Finnish company and at the same time Estonian authorities informed of a S. enteritidis PT 1B outbreak linked to chicken wrap prepared at an Estonian restaurant. We found that chicken salad was associated with the infection (odds ratio (OR) 16·1, 95% confidence interval (CI) 1·7-148·7 for consumption and OR 17·5...
August 3, 2017: Epidemiology and Infection
https://www.readbyqxmd.com/read/28770644/the-combined-effect-of-sango-sprout-juice-and-caloric-restriction-on-metabolic-disorders-and-gut-microbiota-composition-in-an-obesity-model
#3
Fabio Vivarelli, Donatella Canistro, Clara Babot Marquillas, Silvia Cirillo, Gina R De Nicola, Renato Iori, Giacomo Biagi, Carlo Pinna, Fabio Gentilini, Luisa Pozzo, Vincenzo Longo, Moreno Paolini
The main purpose of this study was to compare the benefits of SSJ supplementation in obese rats with those achieved only by switching the alimentary regimen from high-fat (HFD) to the regular one (RD) in liver, ileum and prostate. Furthermore, changings in caecal chime microbiota were investigated. SSJ was administered to rats in combination with a RD (HFD-RD + SSJ). The switch from HFD to RD led to a weight loss of almost 9.8 g, and the total cholesterol was found to be significantly lower. In the HFD-RD + SSJ group, all values were improved compared with the HFD control, and the weight decrement was higher (-23...
August 3, 2017: International Journal of Food Sciences and Nutrition
https://www.readbyqxmd.com/read/28761845/angiolymphoid-hyperplasia-with-eosinophilia-and-its-response-to-the-combination-of-radiofrequency-ablation-and-topical-timolol
#4
Pooja Arora, Neha Meena, Prafulla K Sharma, Minakshi Bhardwaj
Angiolymphoid hyperplasia with eosinophilia is a rare vascular disease characterized by multiple erythematous to violaceous papules, commonly present on the head and neck region. We report a case of a 23-year-old female who presented with multiple, erythematous asymptomatic papules on the preauricular region and pinna, which on biopsy was suggestive of angiolymphoid hyperplasia. The lesions were treated with a novel combination of radiofrequency ablation and topical timolol. The lesions healed without scarring and there was no recurrence on 1 year follow up...
July 2017: Indian Dermatology Online Journal
https://www.readbyqxmd.com/read/28758797/an-in-vitro-evaluation-of-the-effects-of-a-yucca-schidigera-extract-and-chestnut-tannins-on-composition-and-metabolic-profiles-of-canine-and-feline-faecal-microbiota
#5
Carlo Pinna, Carla Giuditta Vecchiato, Vladimiro Cardenia, Maria Teresa Rodriguez-Estrada, Claudio Stefanelli, Monica Grandi, Pier Paolo Gatta, Giacomo Biagi
The in vitro effect of a Yucca schidigera extract (YSE) and tannins from chestnut wood on composition and metabolic activity of canine and feline faecal microbiota was evaluated. Four treatments were carried out: control diet, chestnut tannins (CT), YSE and CT + YSE. The YSE was added to canine and feline faecal cultures at 0.1 g/l, while CT were added at 0.3 g/l for a 24-h incubation. A total of 130 volatile compounds were detected by means of headspace-solid phase microextraction gas-chromatography/mass spectrometry analyses...
July 31, 2017: Archives of Animal Nutrition
https://www.readbyqxmd.com/read/28758427/genome-wide-dna-methylation-profiling-of-the-regenerative-mrl-mpj-mouse-and-two-normal-strains
#6
Bartosz Górnikiewicz, Anna Ronowicz, Piotr Madanecki, Paweł Sachadyn
AIM: We aimed to identify the pivotal differences in the DNA methylation profiles between the regeneration capable MRL/MpJ mouse and reference mouse strains. MATERIALS & METHODS: Global DNA methylation profiling was performed in ear pinnae, bone marrow, spleen, liver and heart from uninjured adult females of the MRL/MpJ and C57BL/6J and BALB/c. RESULTS & CONCLUSION: A number of differentially methylated regions (DMRs) distinguishing between the MRL/MpJ mouse and both references were identified...
July 31, 2017: Epigenomics
https://www.readbyqxmd.com/read/28756716/impact-of-hepatitis-c-virus-infection-on-health-related-quality-of-life-before-and-after-liver-transplantation-a-multidisciplinary-point-of-view
#7
Lucia Golfieri, Stefano Gitto, Maria Cristina Morelli, Antonio Daniele Pinna, Silvana Grandi, Pietro Andreone
Hepatitis C negatively changes patient quality of life even in the absence of advanced liver disease. The specific patterns of quality of life of hepatitis C positive patients waiting for transplant or after surgery are not widely studied. Areas covered: A significant percentage of infected patients show cognitive impairment, fatigue, and/or a 'brain fog', that cannot be explained by the liver disease. Depression can be diagnosed in one third of hepatitis C positive patients. Conflicting data are available regarding the possible role of Model for End-Stage Liver Disease score as predictor of impaired quality of life...
August 2017: Expert Review of Anti-infective Therapy
https://www.readbyqxmd.com/read/28753933/deciphering-molecular-mechanisms-of-interface-buildup-and-stability-in-porous-si-eumelanin-hybrids
#8
Elisa Pinna, Claudio Melis, Aleandro Antidormi, Roberto Cardia, Elisa Sechi, Giancarlo Cappellini, Marco d'Ischia, Luciano Colombo, Guido Mula
Porous Si/eumelanin hybrids are a novel class of organic-inorganic hybrid materials that hold considerable promise for photovoltaic applications. Current progress toward device setup is, however, hindered by photocurrent stability issues, which require a detailed understanding of the mechanisms underlying the buildup and consolidation of the eumelanin-silicon interface. Herein we report an integrated experimental and computational study aimed at probing interface stability via surface modification and eumelanin manipulation, and at modeling the organic-inorganic interface via formation of a 5,6-dihydroxyindole (DHI) tetramer and its adhesion to silicon...
July 19, 2017: International Journal of Molecular Sciences
https://www.readbyqxmd.com/read/28749307/recurrent-ear-mite-otodectes-cynotis-infestation-in-three-related-groups-of-patagonian-cavies-dolichotis-patagonum
#9
Carolina Lopes da Cruz, Torres Alpino, Jack Kottwitz
:  Two of three groups of Patagonian cavies ( Dolichotis patagonum ) contracted Otodectes cynotis infestations after exposure to mite-infested feral cats. Otodectes cynotis infestations were initially identified in 9 of 10 cavies in group 1. Multiple feral cats with O. cynotis infestations were observed in the vicinity of the Patagonian cavies and were subsequently removed. The Patagonian cavies were initially treated with ivermectin (0.4 mg/kg s.q.) every 2 wk, but ivermectin was discontinued after the third treatment due to injury to one of the Patagonian cavies during capture...
June 2017: Journal of Zoo and Wildlife Medicine: Official Publication of the American Association of Zoo Veterinarians
https://www.readbyqxmd.com/read/28745399/average-treatment-effect-of-hepatic-resection-versus-locoregional-therapies-for-hepatocellular-carcinoma
#10
A Cucchetti, V Mazzaferro, A D Pinna, C Sposito, R Golfieri, C Serra, C Spreafico, F Piscaglia, A Cappelli, M Bongini, M Cucchi, M Cescon
BACKGROUND: When comparing the efficacy of surgical and non-surgical therapies for hepatocellular carcinoma (HCC), a major limitation is the causal inference problem. This concerns the impossibility of seeing both outcomes of two different treatments for the same individual at the same time because one is inevitably missing. This aspect can be addressed methodologically by estimating the so-called average treatment effect (ATE). METHODS: To estimate the ATE of hepatic resection over locoregional therapies for HCC, data from patients treated in two tertiary care settings between August 2000 and December 2014 were used to obtain counterfactual outcomes using an inverse probability weight survival adjustment...
July 26, 2017: British Journal of Surgery
https://www.readbyqxmd.com/read/28732597/pattern-of-gene-expression-in-different-stages-of-schizophrenia-down-regulation-of-nptx2-gene-revealed-by-a-meta-analysis-of-microarray-datasets
#11
Mirko Manchia, Ignazio S Piras, Matthew J Huentelman, Federica Pinna, Clement C Zai, James L Kennedy, Bernardo Carpiniello
Schizophrenia (SCZ) is a severe psychiatric disorder with a genetic susceptibility. Alterations in neurochemical signaling, as well as changes in brain structure and function, manifest during the course of SCZ and are likely causative of the symptoms shown by affected individuals. However, little is known about the timing of these changes, particularly in the pre-morbid and prodromal phases of SCZ. Here, we performed a gene-based and pathway-based meta-analysis of 5 microarray datasets from human induced pluripotent stem cells (hiPSCs)-derived neurons and post-mortem brain tissue from SCZ and healthy controls (HC), with the underlying assumption they might represent the neurobiological make-up of SCZ in the pre-morbid and chronic stages of illness, respectively...
July 18, 2017: European Neuropsychopharmacology: the Journal of the European College of Neuropsychopharmacology
https://www.readbyqxmd.com/read/28729532/doping-porous-silicon-with-erbium-pores-filling-as-a-method-to-limit-the-er-clustering-effects-and-increasing-its-light-emission
#12
Guido Mula, Tony Printemps, Christophe Licitra, Elisa Sogne, Francesco D'Acapito, Narciso Gambacorti, Nicola Sestu, Michele Saba, Elisa Pinna, Daniele Chiriu, Pier Carlo Ricci, Alberto Casu, Francesco Quochi, Andrea Mura, Giovanni Bongiovanni, Andrea Falqui
Er clustering plays a major role in hindering sufficient optical gain in Er-doped Si materials. For porous Si, the long-standing failure to govern the clustering has been attributed to insufficient knowledge of the several, concomitant and complex processes occurring during the electrochemical Er-doping. We propose here an alternative road to solve the issue: instead of looking for an equilibrium between Er content and light emission using 1-2% Er, we propose to significantly increase the electrochemical doping level to reach the filling the porous silicon pores with luminescent Er-rich material...
July 20, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28724422/assessment-of-eating-disorders-with-the-diabetes-eating-problems-survey-revised-deps-r-in-a-representative-sample-of-insulin-treated-diabetic-patients-a-validation-study-in-italy
#13
Federica Pinna, Enrica Diana, Lucia Sanna, Valeria Deiana, Mirko Manchia, Eraldo Nicotra, Andrea Fiorillo, Umberto Albert, Alessandra Nivoli, Umberto Volpe, Anna Rita Atti, Silvia Ferrari, Federica Medda, Maria Gloria Atzeni, Daniela Manca, Elisa Mascia, Fernando Farci, Mariangela Ghiani, Rossella Cau, Marta Tuveri, Efisio Cossu, Elena Loy, Alessandra Mereu, Stefano Mariotti, Bernardo Carpiniello
BACKGROUND: The purpose of the study was to evaluate in a sample of insulin-treated diabetic patients, with type 1 or type 2 diabetes, the psychometric characteristics of the Italian version of the DEPS-R scale, a diabetes-specific self-report questionnaire used to analyze disordered eating behaviors. METHODS: The study was performed on 211 consecutive insulin-treated diabetic patients attending two specialist centers. Lifetime prevalence of eating disorders (EDs) according to DSM-IV and DSM-5 criteria were assessed by means of the Module H of the Structured Clinical Interview for DSM IV Axis I Disorder and the Module H modified, according to DSM-5 criteria...
July 19, 2017: BMC Psychiatry
https://www.readbyqxmd.com/read/28722128/solar-insolation-in-springtime-influences-age-of-onset-of-bipolar-i-disorder
#14
M Bauer, T Glenn, M Alda, M A Aleksandrovich, O A Andreassen, E Angelopoulos, R Ardau, Y Ayhan, C Baethge, S R Bharathram, R Bauer, B T Baune, C Becerra-Palars, F Bellivier, R H Belmaker, M Berk, Y Bersudsky, Ş Bicakci, H Birabwa-Oketcho, T D Bjella, L Bossini, J Cabrera, E Y W Cheung, M Del Zompo, S Dodd, M Donix, B Etain, A Fagiolini, K N Fountoulakis, M A Frye, A Gonzalez-Pinto, J F Gottlieb, P Grof, H Harima, C Henry, E T Isometsä, S Janno, F Kapczinski, M Kardell, S Khaldi, S Kliwicki, B König, T L Kot, R Krogh, M Kunz, B Lafer, M Landén, E R Larsen, U Lewitzka, R W Licht, C Lopez-Jaramillo, G MacQueen, M Manchia, W Marsh, M Martinez-Cengotitabengoa, I Melle, F Meza-Urzúa, M Yee Ming, S Monteith, G Morken, E Mosca, R Munoz, S V Mythri, F Nacef, R K Nadella, F G Nery, R E Nielsen, C O'Donovan, A Omrani, Y Osher, H Østermark Sørensen, U Ouali, Y Pica Ruiz, M Pilhatsch, M Pinna, F D R da Ponte, D Quiroz, R Ramesar, N Rasgon, M S Reddy, A Reif, P Ritter, J K Rybakowski, K Sagduyu, Â M Scippa, E Severus, C Simhandl, D J Stein, S Strejilevich, M Subramaniam, A H Sulaiman, K Suominen, H Tagata, Y Tatebayashi, L Tondo, C Torrent, A E Vaaler, J Veeh, E Vieta, B Viswanath, M Yoldi-Negrete, M Zetin, Y Zgueb, P C Whybrow
OBJECTIVE: To confirm prior findings that the larger the maximum monthly increase in solar insolation in springtime, the younger the age of onset of bipolar disorder. METHOD: Data were collected from 5536 patients at 50 sites in 32 countries on six continents. Onset occurred at 456 locations in 57 countries. Variables included solar insolation, birth-cohort, family history, polarity of first episode and country physician density. RESULTS: There was a significant, inverse association between the maximum monthly increase in solar insolation at the onset location, and the age of onset...
July 19, 2017: Acta Psychiatrica Scandinavica
https://www.readbyqxmd.com/read/28718994/hemifacial-microsomia-in-a-cat
#15
R B Song, M Kent, E N Glass, G J Davis, F A Castro, A de Lahunta
A 7-month-old domestic medium hair cat presented with facial asymmetry affecting the bony and soft tissue structures of the right side of the head including the maxilla, nose, eye and pinna of the ear. Additionally, neurological dysfunction of the facial and vestibulocochlear nerves on the affected side was present. A congenital malformation affecting the first and second embryologic pharyngeal arches was suspected. This is the first case of hemifacial microsomia of likely congenital origin reported in a cat...
July 18, 2017: Anatomia, Histologia, Embryologia
https://www.readbyqxmd.com/read/28704491/phyto-toponyms-of-arbutus-unedo-l-and-their-distribution-in-sardinia-italy
#16
Claudia Pinna, Luisa Carta, Vitale Deiana, Ignazio Camarda
The study shows the results of an inventory of place names connected to Arbutus unedo L., a Mediterranean species, widespread throughout Sardinia. The main aim was to compare the past distribution of place names, referring to the strawberry tree, to the current distribution of the species on the island. In addition, we investigated the meaning and the diversity of these local place names in the various communities. The result was a collection of 432 phyto-toponyms. 248 of them were used for an analysis of their distribution in the habitats, indicated on the Map of the Nature System in Sardinia, defined on the basis of the current vegetation typology...
2017: PloS One
https://www.readbyqxmd.com/read/28700701/development-and-validation-of-the-maugeri-sleep-quality-and-distress-inventory-masqudi-17
#17
Elisa Morrone, Cinzia Sguazzin, Giorgio Bertolotti, Andrea Giordano, Alberto Braghiroli, Gian Luigi Balestroni, Raffaele Manni, Luigi Ferini Strambi, Vincenza Castronovo, Marco Zucconi, Fabrizio De Carli, Eleonora Pinna, Marcella Ottonello, Ines Giorgi, Michele Terzaghi, Sara Marelli, Francesco Fanfulla
OBJECTIVES: The aim of this study was to develop and validate a questionnaire designed to measure the impact of sleep impairment on emotional distress in patients with various sleep disorders. METHODS: Five experts created an item data-bank pertaining to sleep-related psychological symptoms and somatic perceptions. Fifty patients in two focus groups examined each item for: a) word clarity (indicating any ambiguity of interpretation) and b) appropriateness for the target population...
2017: PloS One
https://www.readbyqxmd.com/read/28692071/-charges-and-convictions-of-psychiatrists-for-the-violent-behavior-of-the-patient-psychiatric-forensic-remarks
#18
Giancarlo Nivoli, Liliana Lorettu, Bernardo Carpiniello, Paolo Milia, Federica Pinna, Andrea Lepretti, Cristiano Depalmas, Alessandra M A Nivoli
Purpose of the present study is to point-out a number of psychiatric-forensic remarks about the management of violent behavior against the person (VBP) amongst psychiatric patients. The study is the authors' personal contribution based on clinical and forensic experience as experts in the management of psychiatric patients with VBP. Twelve psychiatric-forensic remarks have been highlighted in the present study: 1) VBP is a multifactorial event; 2) the risk of VBP against the person may change rapidly over time in quantity and quality; 3) there are no methods for reliable prediction of VBP in a single clinical-case; 4) there are no medications with an indication of "heal" the VBP; 5) there are no therapeutic measures that neutralize always, quickly and without recurrences VBP; 6) there exist clinical hypotheses to assess VBP; 7) there exist principles of victimology to assess VBP; 8) there are emotional reactions that can affect the evaluation and clinical and forensic management of VBP; 9) the responsibility of the psychiatrist has to be evaluated at the moment of the events; 10) the responsibility of the psychiatrist must be contextualized in the single clinical-case; 11) there is the need to clarify the individual professional responsibility of psychiatrists who treated a patient; 12) there is the need to clarify the criteria for the definition of the guarantee role...
May 2017: Rivista di Psichiatria
https://www.readbyqxmd.com/read/28685087/heterogeneity-in-the-colorectal-primary-tumor-and-the-synchronous-resected-liver-metastases-prior-to-and-after-treatment-with-an-anti-egfr-monoclonal-antibody
#19
Daniela Adua, Francesca Di Fabio, Giorgio Ercolani, Michelangelo Fiorentino, Elisa Gruppioni, Annalisa Altimari, Fabiola Lorena Rojas Limpe, Nicola Normanno, Antonio Daniele Pinna, Carmine Pinto
Molecular heterogeneity between primary tumors (PTs) and synchronous resected liver metastasis in colorectal cancer (CRC) has potential relevance in treatment strategies. Next-generation sequencing (NGS) may be able to increase the chances of identifying multiple molecular driver alterations, calling for therapy. The aim of the present study was to evaluate mutations in PT and synchronous resected liver metastases for patients with Kirsten rat sarcoma 2 viral oncogene homolog (KRAS) exon 2 wild-type metastatic (m)CRC who underwent chemotherapy (CT) featuring an anti-epidermal growth factor receptor (EGFR) monoclonal antibody...
July 2017: Molecular and Clinical Oncology
https://www.readbyqxmd.com/read/28681343/detectable-cerebrospinal-fluid-jcv-dna-in-late-presenting-hiv-positive-patients-beyond-progressive-multifocal-leukoencephalopathy
#20
S Mornese Pinna, E Scarvaglieri, M G Milia, D Imperiale, V Ghisetti, S Audagnotto, A Prochet, F Lipani, S Bonora, G Di Perri, A Calcagno
In the absence of effective prophylaxis and treatment, therapeutic options in HIV-positive patients with progressive multifocal leukoencephalopathy (PML) are limited to antiretroviral therapy: nevertheless, outcome is poor. We conducted a retrospective study (2009-2015) describing the outcome of 25 HIV-positive patients with detectable cerebrospinal fluid JC virus DNA: 14 had a probable PML while the others had evidence of other inflammatory central nervous system (CNS) affecting disorders. In the former group, 6-month mortality was 45...
July 5, 2017: Journal of Neurovirology
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