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https://www.readbyqxmd.com/read/29042946/the-effects-of-y-shaped-conchal-cartilage-transplantation-on-the-correction-of-nasal-deformity-secondary-to-cleft-lip-and-its-influence-on-mental-health
#1
Ling Liu, Wei Wang, Lin Yang, Hongchuang Zhang
Patients who undergo corrective surgery for cleft lip are known to be at risk for subsequently developing secondary nasal deformity. The aim of this study was to investigate the effects of Y-shaped conchal cartilage transplantation on the correction of nasal deformity secondary to cleft lip and its influence on mental health. Sixteen patients with nasal deformity secondary to cleft lip admitted to The First People's Hospital Xuzhou (Xuzhou, China) from February 2014 to February 2015 were selected for the study...
October 2017: Experimental and Therapeutic Medicine
https://www.readbyqxmd.com/read/29021427/petrified-ear-auricles-with-isolated-adrenocorticotropic-hormone-deficiency
#2
Takafumi Taguchi, Manatsu Yoshida, Yoshio Terada
No abstract text is available yet for this article.
October 11, 2017: Internal Medicine
https://www.readbyqxmd.com/read/29019876/unique-circumferential-peripheral-keratitis-in-relapsing-polychondritis-a-case-report
#3
Naohiro Motozawa, Takahiro Nakamura, Seiji Takagi, Masashi Fujihara, Yasuhiko Hirami, Kazuhiro Ishida, Chie Sotozono, Yasuo Kurimoto
RATIONALE: Relapsing polychondritis (RP) is a rare collagen disease characterized by inflammation and destruction of cartilage throughout the body. The paper details the clinical course of a case of RP with unique circumferential peripheral keratitis. PATIENT CONCERNS: A 54-year-old Japanese woman was referred to the hospital presenting with auricular and ocular pain. DIAGNOSES: Based on the auricle biopsy results and the three presenting symptoms (bilateral auricular chondritis, inflammatory arthritis and ocular inflammation), her condition was diagnosed as RP...
October 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28994539/-siwu-decoction-improves-iron-deficiency-anemia-in-infant-rats-and-regulates-iron-metabolism
#4
Ran He, Hong-Jin Wang, Ying Zhou, Jing-Jing Li, Xiao-Yu Xu
To investigate the effect of Siwu decoction on improving iron deficiency anemia in infant rats and observe its regulatory effects on iron metabolism. SD rats were fed with low iron fodder for 2 weeks, and then the rats with hemoglobin level less than 75 g•L ⁻¹ were screened out and randomly divided into model group, Ferrous succinate 50 mg•kg ⁻¹ group, Siwu decoction 4 g•kg ⁻¹, 8 g•kg ⁻¹ and 16 g•kg ⁻¹ groups. After 4 weeks' gavage administration, Wright-Giemsa's staining of blood smear and HE staining of the livers were conducted, and all rats were tested for blood routine, serum iron, total iron binding capacity, serum ferritin, serum hepcidin and liver hepcidin...
March 2017: Zhongguo Zhong Yao za Zhi, Zhongguo Zhongyao Zazhi, China Journal of Chinese Materia Medica
https://www.readbyqxmd.com/read/28993896/rcan1-mutation-and-functional-characterization-in-children-with-sporadic-congenital-heart-disease
#5
Xiaoyong Li, Lei Shi, Ming Xu, Xun Zheng, Yiwen Yu, Jing Jin
Congenital heart disease (CHD) is the most frequent birth defect. RCAN1 (regulator of calcineurin 1) contributes to CHD in Down syndrome. However, whether RCAN1 is also associated with nonsyndromic CHD remains unclear. This study sequenced the exons and flanking region of RCAN1 in 128 sporadic CHD patients and 150 normal controls. We identified six novel heterozygous mutations in CHD patients. Functional assay showed that the g.482G>T could obviously raise the promoter activity of RCAN1.4 in vitro; However, we failed to detect the expression of RCAN1 in the right auricle, which made it confused to evaluate the pathogenicity of this mutation...
October 9, 2017: Pediatric Cardiology
https://www.readbyqxmd.com/read/28984809/otology-at-the-academy-of-gondishapur-200-600-ce
#6
Robert J Ruben
OBJECTIVE: To investigate the way in which otology was practiced at the Academy of Gondishapur in ancient Persia from 200 to 600 CE. METHOD: The pertinent literature, using German and English translations of Latin, Greek, Arabic, and Sanskrit documents, was identified and reviewed through the indices of available books and through a PDF search for the following topics: auricle, deaf, deafness, dizziness, ear, hearing, medicine, otitis, pinna, punishment-ear, speech, surgery, vertigo, and voice...
October 4, 2017: Otology & Neurotology
https://www.readbyqxmd.com/read/28974256/exosomes-of-human-placenta-derived-mesenchymal-stem-cells-stimulate-angiogenesis
#7
Motohiro Komaki, Yuri Numata, Chikako Morioka, Izumi Honda, Masayuki Tooi, Naoki Yokoyama, Hirohito Ayame, Kengo Iwasaki, Atsuko Taki, Noriko Oshima, Ikuo Morita
BACKGROUND: The therapeutic potential of mesenchymal stem cells (MSCs) may be attributed partly to humoral factors such as growth factors, cytokines, and chemokines. Human term placental tissue-derived MSCs (PlaMSCs), or conditioned medium left over from cultures of these cells, have been reported to enhance angiogenesis. Recently, the exosome, which can transport a diverse suite of macromolecules, has gained attention as a novel intercellular communication tool. However, the potential role of the exosome in PlaMSC therapeutic action is not well understood...
October 3, 2017: Stem Cell Research & Therapy
https://www.readbyqxmd.com/read/28972475/mixed-type-basal-cell-carcinoma-of-the-auricle-single-stage-reconstruction-after-r0-resection-by-a-modified-antia-buch-flap-clinical-case-report
#8
A Goldman, U Wollina
Basal cell carcinoma (BCC) is the most common neoplasia in Caucasians with a pre-dominance for the sun-exposed anatomical areas including the auricle. The treatment of choice is surgery achieving an R0-resection status. On the other hand, functional and aesthetic results are of importance. We report a case of 79-year-old Caucasian man with a BCC of the helical rim that was treated surgically using a modified Antia-Buch flap for single stage reconstruction. Article is discussing peculiarities of BCC on the auricle and options for auricular reconstruction...
September 2017: Georgian Medical News
https://www.readbyqxmd.com/read/28964287/aesthetic-and-hearing-rehabilitation-in-patients-with-bilateral-microtia-atresia
#9
Xinmiao Fan, Yibei Wang, Pu Wang, Yue Fan, Yu Chen, Yuanli Zhu, Xiaowei Chen
OBJECTIVES: To evaluate the safety and efficacy of auricle reconstruction and active transcutaneous bone-conduction implantation in patients with bilateral microtia-atresia. DESIGN: Patients were chosen prospectively, with each being his/her own control. SETTING: The setting was a tertiary referral center. PARTICIPANTS: Twelve patients, aged 6-18 years, with bilateral microtia-atresia suffering from bilateral conductive hearing loss...
October 2017: International Journal of Pediatric Otorhinolaryngology
https://www.readbyqxmd.com/read/28953580/relapsing-polychondritis-with-increased-bone-marrow-signal-on-magnetic-resonance-imaging-in-a-13-year-old-girl
#10
Kanako Nakayama, Masafumi Yamada, Yusuke Tozawa, Yuji Nakamaru, Masahiro Ueki, Shunichiro Takezaki, Hiroki Nishimura, Tomoko Mitsuhashi, Noriko Oyama-Manabe, Keita Sakamoto, Ryuta Arai, Sayaka Yamamoto, Kimiaki Uetake, Tadashi Ariga
Relapsing polychondritis (RPC) is an inflammatory disorder predominantly affecting cartilaginous structures including ears, nose, joints, and respiratory tracts. Although RPC is rare in children, previous reports indicated childhood RPC is atypical or severe. A 13-year-old girl presented with redness and swelling of the bilateral auricles and subsequently developed arthralgia of multiple joints. Histopathologic findings of the auricular cartilages were compatible with RPC. Magnetic resonance imaging (MRI) for the evaluation of arthralgia unexpectedly demonstrated increased bone marrow signal of metacarpals and the distal epiphysis of radii and ulnae...
September 26, 2017: Journal of Clinical Rheumatology: Practical Reports on Rheumatic & Musculoskeletal Diseases
https://www.readbyqxmd.com/read/28942231/the-folded-postauricular-flap-a-novel-approach-to-reconstruction-of-large-full-thickness-defects-of-the-conchal-bowl
#11
Ansley M Roche, Martha Griffin, Ron Shelton, Mark L Urken
Extensive subtotal full-thickness auriculectomy defects pose a challenge for the reconstructive surgeon. The posterior island flap (PIF), based on the posterior auricular artery, has been described as a reconstructive option for auricular defects, with reports describing a "pull-through" or "revolving door" technique to reconstruct subtotal partial thickness and full thickness auricular defects. These techniques may result in posterior "pinning" of the auricle. This patient is an 87-year-old male who presented after Mohs excision of squamous cell carcinoma of the conchal bowl, which resulted in a 4x4cm subtotal auriculectomy defect...
September 19, 2017: American Journal of Otolaryngology
https://www.readbyqxmd.com/read/28940541/ebstein-anomaly-and-sudden-childhood-death
#12
Amanda Freeman, Roger W Byard
A 13-year-old girl is reported who died suddenly and unexpectedly in her sleep from previously undiagnosed Ebstein anomaly. At autopsy, there was dilatation of the right atrium with marked dilatation of the right auricle and apical displacement of the tricuspid valve into the right ventricular cavity with atrialization of the upper portion of the right ventricle. There were also prominent dysplastic changes in both the septal and posterior leaflets of the tricuspid valve with thickening of the valve and fusion of leaflets to the wall of the ventricle...
September 20, 2017: Journal of Forensic Sciences
https://www.readbyqxmd.com/read/28940518/sandwich-compression-with-rubbery-tourniquet-sheets-and-cotton-balls-for-auricular-pseudocyst
#13
Ming-Ying Wu, Chun-Bing Chen, Yi-Hsi Chen, Catherine Chang, Kai-Chieh Chan
OBJECTIVES/HYPOTHESIS: Pseudocyst of the auricle is a benign, noninflammatory cystic disease that is more common in Asians than in Caucasians. When managed conservatively, the results are often unsatisfactory and recurrences are common. We aimed to introduce a novel modified surgical method that involves a deroofing technique followed by a sandwich compression suture using two rubber tourniquet sheets and an iodine-soaked cotton ball for the treatment of auricular pseudocysts and to ascertain its effectiveness...
September 20, 2017: Laryngoscope
https://www.readbyqxmd.com/read/28930930/management-of-peri-implant-hypertrophic-scarring-for-an-ear-prosthesis
#14
Elizabeth Rodrigues Alfenas, Amália Moreno, Paul Benjamin Tanner, Henrique Duque Netto, Maria Fernanda Lopes Fonseca, Fernando Gonçalves Rios
The clinical report describes a case of a 14-year-old patient with a traumatic amputation of the left auricle and severe hypertrophic scarring. The management of peri-implant soft tissue was challenging, but successful in the rehabilitation of a patient with auricular prosthesis retained by implants. The prosthesis restored the patient's facial aesthetics and contributed not only to function, but also to psychosocial well-being.
September 19, 2017: Journal of Craniofacial Surgery
https://www.readbyqxmd.com/read/28930260/association-between-auricular-signals-and-the-risk-factors-of-metabolic-syndrome
#15
Lorna Kwai Ping Suen, Chao Hsing Yeh, Simon Kai Wang Yeung, Jojo Yee Mei Kwan, Hon Fat Wong, David Chan, Alice Siu Ping Cheung, Vincent Tok Fai Yeung
Objective: This study aims to determine the association between auricular signals and the risk factors of metabolic syndrome (MS). Methods: A case-control study with an equal number of cases and controls matched by age group and gender was conducted. A total of 204 participants were recruited. Patients were verified as having MS based on the International Diabetes Federation (IDF) criteria. Auricular assessment was conducted in the following sequence: visual inspection, electrical skin resistance test (ESRT), and pressure pain test (PPT)...
June 25, 2017: Medicines (Basel, Switzerland)
https://www.readbyqxmd.com/read/28919362/a-homozygote-trex1-mutation-in-two-siblings-with-different-phenotypes-chilblains-and-cerebral-vasculitis
#16
Rabia Miray Kisla Ekinci, Sibel Balci, Atil Bisgin, Derya Ufuk Altintas, Mustafa Yılmaz
Three prime repair exonuclease 1 degrades single and double stranded DNA with 3'-5' nuclease activity and its mutations are related to type 1 IFN mediated autoinflammation due to accumulated intracellular nucleic acids. To date, several cases of systemic lupus erythematosus, Aicardi-Goutieres syndrome, familial chilblain lupus, retinal vasculopathy-cerebral leukodystrophy have been reported with TREX1 mutations. Chilblain lupus is a skin disease characterized by blue-reddish coloring, swelling or ulcers on acral regions of body such as fingertips, heels, nose and auricles...
September 12, 2017: European Journal of Medical Genetics
https://www.readbyqxmd.com/read/28913303/simultaneous-development-of-three-different-neoplasms-of-trichilemmoma-desmoplastic-trichilemmoma-and-basal-cell-carcinoma-arising-from-nevus-sebaceus
#17
Chi An Lee, Seok Joo Kang, Seong Pin Jeon, Hook Sun, Mi Seon Kang
Nevus sebaceus is a hamartoma of the sebaceous gland that occurs congenitally, from which various secondary tumors can arise with a prevalence of 5%-6%. Benign neoplasms commonly arise from nevus sebaceous, but they have a very low malignant potential. Two neoplasms may occasionally arise within the same lesion, but it is rare for three or more neoplasms to occur in a nevus sebaceus simultaneously. A 61-year-old male patient was admitted to our hospital for a 4 cm×2.5 cm growing tumor in a verrucous form arising within a periauricular nevus sebaceus in the post auricle of the left ear that had developed 30 years earlier...
March 2017: Arch Craniofac Surg
https://www.readbyqxmd.com/read/28875091/demographics-of-head-and-neck-cancer-patients-a-single-institution-experience
#18
George S Stoyanov, Martina Kitanova, Deyan L Dzhenkov, Peter Ghenev, Nikolay Sapundzhiev
Introduction Head and neck cancer (HNC) comprises a diverse group of oncological entities, originating from various tissue types and organ localizations, situated in the topographical regions of the head and neck (H&N). This single institution retrospective study was aimed at establishing the HNC patient demographics and categorizing the individual incidence of H&N malignancies, regarding their organ of origin and main histopathological type. Materials and methods All histologically verified cases of HNC from a single tertiary referral center were reviewed in a descriptive retrospective manner...
July 2, 2017: Curēus
https://www.readbyqxmd.com/read/28852299/a-simplified-reconstructive-technique-for-full-thickness-central-defects-of-the-auricle-with-the-use-of-a-post-auricular-folded-flap
#19
Ioannis Papadiochos, Eleni Bourlidou, Doxa Mangoudi
BACKGROUND: Post-auricular flaps have proved very effective in the reconstruction of most types of partial auricular defects. However, few reports exist regarding the reconstruction of centrally located perforating defects of the auricle. OBJECTIVES: This paper aimed to describe a one-stage technique including a post-auricular folded flap (PAFF) for reconstruction of full-thickness defects of central auricular sites. PATIENTS AND METHODS: Between March 2010 and November 2014, five male patients were treated with this reconstructive technique under local anaesthesia...
April 2017: Journal of Cutaneous and Aesthetic Surgery
https://www.readbyqxmd.com/read/28826779/gene-expression-profiles-in-auricle-skin-as-a-possible-additional-endpoint-for-determination-of-sensitizers-a-multi-endpoint-evaluation-of-the-local-lymph-node-assay
#20
Hiromi Tsuchiyama, Akihisa Maeda, Mayumi Nakajima, Mika Kitsukawa, Kei Takahashi, Tomoya Miyoshi, Mayu Mutsuga, Yoshiji Asaoka, Yohei Miyamoto, Keiyu Oshida
The murine local lymph node assay (LLNA) is widely used to test chemicals to induce skin sensitization. Exposure of mouse auricle skin to a sensitizer results in proliferation of local lymph node T cells, which has been measured by in vivo incorporation of H(3)-methyl thymidine or 5-bromo-2'-deoxyuridine (BrdU). The stimulation index (SI), the ratio of the mean proliferation in each treated group to that in the concurrent vehicle control group, is frequently used as a regulatory-authorized endpoint for LLNA...
October 5, 2017: Toxicology Letters
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