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https://www.readbyqxmd.com/read/28467018/histological-analysis-of-hyalinised-keloidal-collagen-formation-in-earlobe-keloids-over-time-collagen-hyalinisation-starts-in-the-perivascular-area
#1
Noriko M Matsumoto, Wei-Xia Peng, Masayo Aoki, Satoshi Akaishi, Ryuji Ohashi, Rei Ogawa, Zenya Naito
Keloids grow and do not regress. They are characterised histologically by hyalinised keloidal collagen (HKC). HKC amounts vary, and the mechanism by which they form is unclear. To clarify how HKCs form and whether their formation associates with specific clinical features, we studied the histological findings of earlobe keloids and compared them with respective clinical features. A total of 50 earlobe keloids from 43 patients were used for histological analysis of keloid size (mm(2) ), HKC area (mm(2) ) and HKC area ratio (%)...
May 3, 2017: International Wound Journal
https://www.readbyqxmd.com/read/28464401/prevalence-of-coronary-artery-calcification-in-japanese-patients-with-psoriasis-a-close-correlation-with-bilateral-diagonal-earlobe-creases
#2
Masaru Honma, Takashi Shibuya, Takeshi Iwasaki, Shin Iinuma, Noriyoshi Takahashi, Mari Kishibe, Masako Minami-Hori, Akemi Ishida-Yamamoto
Psoriasis is a multifactorial inflammatory disorder, in which the inflammation affects not only the skin but also the other internal organs, and can induce cardiovascular and cerebrovascular involvements. However, few predictive factors of cardiovascular diseases have been clarified in patients with psoriasis. This study was performed to verify whether diagonal earlobe creases (ELC) can reflect the hidden comorbidities in Japanese psoriatic patients. Prevalence and subtypes of ELC were analyzed in patients with psoriatic and with non-psoriatic skin diseases, and the correlation with coronary artery calcification (CAC) or fatty liver (FL) detected by computed tomography...
May 2, 2017: Journal of Dermatology
https://www.readbyqxmd.com/read/28463837/adoptive-cellular-gene-therapy-for-the-treatment-of-experimental-autoimmune-polychondritis-ear-disease
#3
Bin Zhou, Yonggan Liao, Yunkai Guo, Ingo H Tarner, Chunfen Liao, Sisi Chen, Mohammad Habiby Kermany, Hanjun Tu, Sen Zhong, Peijie Chen
In the past, the clinical therapy for autoimmune diseases, such as autoimmune polychondritis ear disease, was mostly limited to nonspecific immunosuppressive agents, which could lead to variable responses. Currently, gene therapy aims at achieving higher specificity and less adverse effects. This concept utilizes the adoptive transfer of autologous T cells that have been retrovirally transduced ex vivo to express and deliver immunoregulatory gene products to sites of autoimmune inflammation. In the animal model of collagen-induced autoimmune polychondritis ear disease (CIAPED), the adoptive transfer of IL-12p40-expressing collagen type II (CII)-specific CD4+ T-cell hybridomas resulted in a significantly lower disease incidence and severity compared with untreated or vector-only-treated animals...
May 3, 2017: ORL; Journal for Oto-rhino-laryngology and its related Specialties
https://www.readbyqxmd.com/read/28460854/diagonal-earlobe-crease-frank-s-sign-a-predictor-of-cerebral-vascular-events
#4
Saleh Nazzal, Basem Hijazi, Luai Khalila, Arnon Blum
BACKGROUND: Frank's sign was first described in 1973 by an American physician (T. Frank). It is a diagonal crease in the earlobe which starts from the tragus to the edge of the auricle in an angle of 45 degrees in varying depths. Frank sign was described as a predictor of future coronary heart disease and peripheral vascular diseases. The aim of the study was to examine the association between Frank sign and the development of ischemic stroke. METHODS: A prospective study that enrolled consecutive patients admitted with an acute ischemic stroke...
April 28, 2017: American Journal of Medicine
https://www.readbyqxmd.com/read/28447992/intravital-microscopy-and-thrombus-induction-in-the-earlobe-of-a-hairless-mouse
#5
Daniel Strüder, Eberhard Grambow, Ernst Klar, Robert Mlynski, Brigitte Vollmar
Thrombotic complications of vascular diseases are one leading cause of morbidity and mortality in industrial nations. Due to the complex interactions between cellular and non-cellular blood components during thrombus formation, reliable studies of the physiology and pathophysiology of thrombosis can only be performed in vivo. Therefore, this article presents an ear model in hairless mice and focuses on the in vivo analysis of microcirculation, thrombus formation, and thrombus evolution. By using intravital fluorescence microscopy and the intravenous (iv) application of the respective fluorescent dyes, a repetitive analysis of microcirculation in the auricle can easily be performed, without the need for surgical preparation...
April 2, 2017: Journal of Visualized Experiments: JoVE
https://www.readbyqxmd.com/read/28445376/defining-temporal-hairline-landmarks
#6
Purushottam A Nagarkar, Jonathan Cheng
Brow dermoids are benign pediatric neoplasms. Endoscopic resection requires incisions placed within the temporal hairline, which is often difficult to reliably locate in infants. The authors studied adult and pediatric patients to define the location of the hairline in relationship to simple facial landmarks. Adult and pediatric patients who were seen in preoperative consultation for facial surgical procedures were identified and included in the study. Patients with a history of facial trauma, surgery, or congenital anomalies were excluded...
May 2017: Plastic and Reconstructive Surgery
https://www.readbyqxmd.com/read/28442093/earlobe-crease-in-patient-with-chest-pain
#7
Damien Contou, Marie Lecronier, Tomas Urbina, Nicolas de Prost
No abstract text is available yet for this article.
May 2017: Annals of Emergency Medicine
https://www.readbyqxmd.com/read/28438303/relation-of-the-bilateral-earlobe-crease-to-endothelial-dysfunction
#8
Nozomu Oda, Tatsuya Maruhashi, Shinji Kishimoto, Masato Kajikawa, Yumiko Iwamoto, Akimichi Iwamoto, Shogo Matsui, Takayuki Hidaka, Yasuki Kihara, Kazuaki Chayama, Chikara Goto, Yoshiki Aibara, Ayumu Nakashima, Kensuke Noma, Harutoyo Hirano, Yukihito Higashi
The presence of an earlobe crease (ELC) may be a simple sign to predict atherosclerosis. We evaluated the relation between ELC and vascular function. We measured flow-mediated vasodilation (FMD) and nitroglycerine-induced vasodilation (NID) and observed bilateral earlobes in 400 consecutive subjects. At first, the subjects were divided into 3 groups: non-ELC group, unilateral ELC group, and bilateral ELC group. FMD and NID were significantly lower in the unilateral and bilateral ELC groups than those in the non-ELC group...
March 29, 2017: American Journal of Cardiology
https://www.readbyqxmd.com/read/28416164/morphological-variability-of-the-earlobe-in-a-spanish-population-sample
#9
O Rubio, V Galera, M C Alonso
This article shows the morphological variability of the earlobe in a Spanish population of European origin. The frequencies of four lobe characteristics (attachment, contour, modeling, and size) and their degree of expression were studied. The relationship among the characteristics and the differences involving sex and laterality were also considered. The least frequent morphology, and of main use in solving forensic cases, was the very small size with triangle-pulled contour into the skin and crossed-discontinuous modeling...
March 29, 2017: Homo: Internationale Zeitschrift Für die Vergleichende Forschung Am Menschen
https://www.readbyqxmd.com/read/28385569/-earlobe-reconstruction-in-one-step-by-the-gavello-s-procedure-surgical-technique-and-a-case-report
#10
M Atlan, Q Qassemyar, C Lkah
The earlobe because of its anatomical position is subject of defects secondary to multiple and varied etiologies. Although its functional role appears negligible, its aesthetic and social importance makes its reconstruction a delicate surgery because it must be discreet but also the simplest possible. Many methods have been described but some require several operating times. The aim of this article is to present a simple procedure with a bilobed flap based on a reliable vascularization and which requires only one operative time...
April 3, 2017: Annales de Chirurgie Plastique et Esthétique
https://www.readbyqxmd.com/read/28346638/repair-of-the-dilated-earlobe
#11
Akshay Sanan, Ryan Heffelfinger
No abstract text is available yet for this article.
March 2017: Ear, Nose, & Throat Journal
https://www.readbyqxmd.com/read/28343784/a-modified-intraoral-and-extraoral-approach-osteotomy-for-the-prominent-mandibular-angle
#12
Rui Lei, Yang Wang, Shengquan Xu, Fuliang Hong, Mingyuan Xu, Liyuan Wei, Jinghong Xu
BACKGROUND: A prominent mandibular angle (PMA) is a relatively common condition in Asians, and surgeons typically use the intraoral approach to treat it. However, the approach can have many drawbacks due to the limited operative field and view. The procedures of osteotomy are not easily manipulated, and an exact resection is difficult. In addition, some major complications can easily occur. This article presents a modified osteotomy method for the PMA that avoids these disadvantages and makes the procedure easier to execute...
March 1, 2017: Journal of Plastic, Reconstructive & Aesthetic Surgery: JPRAS
https://www.readbyqxmd.com/read/28331775/diagonal-earlobe-crease-as-a-significant-marker-for-coronary-artery-disease-a-case-control-study
#13
Rida Kamal, Komal Kausar, Ahmed H Qavi, Moeed H Minto, Fariha Ilyas, Salman Assad, Saeed U Shah
OBJECTIVES: To investigate the association between diagonal earlobe crease (DELC) and coronary artery disease (CAD). Limited data exists in South Asia and no prior studies have been performed in Pakistan to assess this relationship. METHODS: In this case-control study, 200 participants from December 2015 to March 2016 at Shifa International Hospital, Islamabad, Pakistan were enrolled. Consecutive non-probability sampling was used to recruit patients. Cases were enrolled from cardiac care unit (CCU) of the hospital with angiography-proven CAD...
February 5, 2017: Curēus
https://www.readbyqxmd.com/read/28284502/palaeopathology-of-the-earlobe-crease-frank-s-sign-new-insights-from-renaissance-art
#14
Francesco M Galassi, Claudio Borghi, Roberta Ballestriero, Michael E Habicht, Maciej Henneberg, Frank J Rühli
Several studies have associated the earlobe crease sign, discovered by Sanders T. Frank in 1973, with cardiovascular pathology, yet very few studies have focused on the antiquity of this trait, with the most ancient one thought to date back to the Roman Emperor Hadrian (76-138CE). This article presents two more cases from the Italian Renaissance in the works of the artist Andrea Mantegna (1431-1506) and examines them in a multidisciplinary fashion.
February 27, 2017: International Journal of Cardiology
https://www.readbyqxmd.com/read/28269732/a-novel-approach-for-chewing-detection-based-on-a-wearable-ppg-sensor
#15
Vasileios Papapanagiotou, Christos Diou, Lingchuan Zhou, Janet van den Boer, Monica Mars, Anastasios Delopoulos
Monitoring of human eating behaviour has been attracting interest over the last few years, as a means to a healthy lifestyle, but also due to its association with serious health conditions, such as eating disorders and obesity. Use of self-reports and other non-automated means of monitoring have been found to be unreliable, compared to the use of wearable sensors. Various modalities have been reported, such as acoustic signal from ear-worn microphones, or signal from wearable strain sensors. In this work, we introduce a new sensor for the task of chewing detection, based on a novel photoplethysmography (PPG) sensor placed on the outer earlobe to perform the task...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28268802/development-of-an-earlobe-crease-identification-system-to-support-diagnosis-of-arteriosclerosis
#16
Harutoyo Hirano, Ryosuke Katsumata, Masato Futagawa, Toshio Tsuji, Shinji Kishimoto, Nozomu Oda, Masato Kajikawa, Tatsuya Maruhashi, Yukihito Higashi
It is well known that an earlobe crease (ELC) is related with cardiovascular disease. However evaluation of ELC has been carried out subjectively. We propose a novel system for objective and quantitative evaluation of ELC characteristics. The outline of earlobe was detected using the Canny edge detector. The number of ELCs and the ratio of the ELC length for the lobule from photographs of bilateral earlobes were calculated from the extracted outline of earlobes. Our system's validity for ELCs detection was compared with doctors' diagnosis using sensitivity and specificity analysis...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28263197/repair-of-a-multisubunit-defect-of-the-earlobe-preauricular-skin-and-superolateral-neck
#17
Michael W Pelster, Melanie A Clark, Simon Yoo
No abstract text is available yet for this article.
May 2017: Dermatologic Surgery: Official Publication for American Society for Dermatologic Surgery [et Al.]
https://www.readbyqxmd.com/read/28227996/a-novel-approach-for-chewing-detection-based-on-a-wearable-ppg-sensor
#18
Vasileios Papapanagiotou, Christos Diou, Lingchuan Zhou, Janet van den Boer, Monica Mars, Anastasios Delopoulos, Vasileios Papapanagiotou, Christos Diou, Lingchuan Zhou, Janet van den Boer, Monica Mars, Anastasios Delopoulos, Janet van den Boer, Vasileios Papapanagiotou, Lingchuan Zhou, Anastasios Delopoulos, Monica Mars, Christos Diou
Monitoring of human eating behaviour has been attracting interest over the last few years, as a means to a healthy lifestyle, but also due to its association with serious health conditions, such as eating disorders and obesity. Use of self-reports and other non-automated means of monitoring have been found to be unreliable, compared to the use of wearable sensors. Various modalities have been reported, such as acoustic signal from ear-worn microphones, or signal from wearable strain sensors. In this work, we introduce a new sensor for the task of chewing detection, based on a novel photoplethysmography (PPG) sensor placed on the outer earlobe to perform the task...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28226997/development-of-an-earlobe-crease-identification-system-to-support-diagnosis-of-arteriosclerosis
#19
Harutoyo Hirano, Ryosuke Katsumata, Masato Futagawa, Toshio Tsuji, Shinji Kishimoto, Nozomu Oda, Masato Kajikawa, Tatsuya Maruhashi, Yukihito Higashi, Harutoyo Hirano, Ryosuke Katsumata, Masato Futagawa, Toshio Tsuji, Shinji Kishimoto, Nozomu Oda, Masato Kajikawa, Tatsuya Maruhashi, Yukihito Higashi, Tatsuya Maruhashi, Toshio Tsuji, Shinji Kishimoto, Masato Kajikawa, Ryosuke Katsumata, Yukihito Higashi, Masato Futagawa, Harutoyo Hirano, Nozomu Oda
It is well known that an earlobe crease (ELC) is related with cardiovascular disease. However evaluation of ELC has been carried out subjectively. We propose a novel system for objective and quantitative evaluation of ELC characteristics. The outline of earlobe was detected using the Canny edge detector. The number of ELCs and the ratio of the ELC length for the lobule from photographs of bilateral earlobes were calculated from the extracted outline of earlobes. Our system's validity for ELCs detection was compared with doctors' diagnosis using sensitivity and specificity analysis...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28207936/th17-cells-and-neutrophils-close-collaborators-in-chronic-leishmania-mexicana-infections-leading-to-disease-severity
#20
C P Pedraza-Zamora, J Delgado-Domínguez, J Zamora-Chimal, I Becker
Cutaneous leishmaniasis caused by Leishmania mexicana is associated with an important inflammatory response. We here analysed the kinetics of Th17 cells and neutrophils in ear lobe lesions caused by Leishmania mexicana throughout 90 days of disease progression in susceptible BALB/c and semi-resistant C57BL/6 mice infected with 1 × 10(5) Leishmania mexicana promastigotes. Cells in the lesions were extracted and quantified by flow cytometry, whereas their distribution in the tissues in relation to the parasites was analysed by immunohistochemistry...
April 2017: Parasite Immunology
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