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https://www.readbyqxmd.com/read/29141287/-observation-of-systemic-adverse-reactions-by-specific-immunotherapy-and-analysis-of-risk-factors-in-allergic-rhinitis
#1
Y Shen, S L Hong, M Zhang, X Ke
Objective: To investigate the systemic adverse effects of specific subcutaneous immunotherapy (SCIT) in patients with allergic rhinitis (AR) and explore the possible risk factors. Methods: A retrospective study was conducted on AR patients who underwent SCIT from January 2014 to January 2017 in Department of Otorhinolaryngology, the First Affiliated Hospital of Chongqing Medical University. For patients with adverse reactions, the detailed medical history during treatment was reviewed. Results: A total of 1608 injections were performed on 102 patients, there were 12 cases / 21 times systemic adverse events, including systemic urticaria, angioedema and Grade Ⅰ systemic adverse reactions...
November 7, 2017: Zhonghua Er Bi Yan Hou Tou Jing Wai Ke za Zhi, Chinese Journal of Otorhinolaryngology Head and Neck Surgery
https://www.readbyqxmd.com/read/29136023/modifications-of-hemoglobin-and-myoglobin-by-maillard-reaction-products-mrps
#2
Aristos Ioannou, Constantinos Varotsis
High performance liquid chromatography (HPLC) coupled with a Fraction Collector was employed to isolate Maillard reaction products (MRPs) formed in model systems comprising of asparagine and monosaccharides in the 60-180°C range. The primary MRP which is detected at 60°C is important for Acrylamide content and color/aroma development in foods and also in the field of food biotechnology for controlling the extent of the Maillard reaction with temperature. The discrete fractions of the reaction products were reacted with Hemoglobin (Hb) and Myoglobin (Mb) at physiological conditions and the reaction adducts were monitored by UV-vis and Attenuated Total Reflection-Fourier transform infrared (FTIR) spectrophotometry...
2017: PloS One
https://www.readbyqxmd.com/read/29129761/are-antiplatelet-and-anticoagulants-drugs-a-risk-factor-for-bleeding-in-mild-traumatic-brain-injury
#3
Laura Uccella, Cesare Zoia, Daniele Bongetta, Paolo Gaetani, Franz Martig, Christian Candrian, Raffaele Rosso
OBJECT: facing mild traumatic brain injury (mTBI) clinicians must decide whether to perform a CT scan to detect a potential intracranial hemorrhage.Many useful guidelines have been developed for general population, but there is no general consensus about the best practice to adopt when dealing with patients on antiplatelet or anticoagulation drugs. The relatively recent introduction of new anticoagulants and second generation antiplatelet drugs poses new challenges in this field. There is no data in the literature about the relative risk of intracranial bleeding in such categories...
November 9, 2017: World Neurosurgery
https://www.readbyqxmd.com/read/29094330/the-association-between-elevated-serum-uric-acid-level-and-an-increased-risk-of-renal-function-decline-in-a-health-checkup-cohort-in-china
#4
Xia Cao, Liuxin Wu, Zhiheng Chen
PURPOSE: To investigate whether an elevated serum uric acid (SUA) level is an independent risk factor for rapid decline in renal function or new-onset chronic kidney disease (CKD) in a Chinese health checkup population. METHODS: A cohort study of 6495 Chinese individuals who underwent health checkups with normal estimated glomerular filtration rate (eGFR) at baseline was carried out from May 2011 to April 2016. Examinations included a questionnaire, physical measurements, and blood sampling...
November 1, 2017: International Urology and Nephrology
https://www.readbyqxmd.com/read/28964555/clinical-applications-of-intra-cardiac-four-dimensional-flow-cardiovascular-magnetic-resonance-a-systematic-review
#5
Saul Crandon, Mohammed S M Elbaz, Jos J M Westenberg, Rob J van der Geest, Sven Plein, Pankaj Garg
BACKGROUND: Four-dimensional flow cardiovascular magnetic resonance (4D flow CMR) is an emerging non-invasive imaging technology used to visualise and quantify intra-cardiac blood flow. The aim of this systematic review is to assess the literature on the current clinical applications of intra-cardiac 4D flow CMR. METHODS: A systematic review was conducted to evaluate the literature on the intra-cardiac clinical applications of 4D flow CMR. Structured searches were carried out on Medline, EMBASE and the Cochrane Library in October 2016...
December 15, 2017: International Journal of Cardiology
https://www.readbyqxmd.com/read/28888704/preparation-of-a-novel-resin-with-acyl-and-thiourea-groups-and-its-properties-for-cu-ii-removal-from-aqueous-solution
#6
Xiaoping Huang, Xiaoyu Cao, Weihong Wang, Hong Zhong, Zhanfang Cao
In this paper, a new resin (PIDTR) containing acyl and thiourea chelating groups was synthesized and its adsorption performances and mechanism to Cu(II) were investigated by adsorption tests, BET, SEM, FTIR and XPS analyses. Equilibrium data were fitted well with Langmuir model with the maximum adsorption capacity of 1.1608 mmol g(-1) for Cu(II) at pH 5.0. The regeneration and reusability test showed that the adsorption capacities decreased from 0.917 mmol g(-1) to 0.88 mmol g(-1) after five cycles of adsorption and desorption...
December 15, 2017: Journal of Environmental Management
https://www.readbyqxmd.com/read/28847139/swimming-three-ice-miles-within-fifteen-hours
#7
Mirko Stjepanovic, Pantelis T. Nikolaidis, Beat Knechtle
Ice Mile swimming (1608 m in water of below 5 °Celsius) is becoming increasingly popular. This case study aimed to identify body core temperature and selected haematological and biochemical parameters before and after repeated Ice Miles. An experienced ice swimmer completed three consecutive Ice Miles within 15 h. Swim times, body core temperatures, and selected urinary and haematological parameters were recorded. Body core temperature reached its maximum between 5, 8 and 15 min after immersion (37.7°C, 38...
August 31, 2017: Chinese Journal of Physiology
https://www.readbyqxmd.com/read/28829690/component-optimization-of-dairy-manure-vermicompost-straw-and-peat-in-seedling-compressed-substrates-using-simplex-centroid-design
#8
Longyuan Yang, Hongliang Cao, Qiaoxia Yuan, Shuai Luo, Zhigang Liu
Vermicomposting is a promising method to disposal dairy manures, and the dairy manure vermicompost (DMV) to replace expensive peat is high-value in the application of seedling compressed substrates. In this research, three main components, DMV, straw, and peat are conducted in the compressed substrates, and the effect of individual component and the corresponding optimal ratio for the seedling production are significant. To address these issues, the simplex-centroid experimental mixture design is employed, and the cucumber seedling experiment is conducted to evaluate the compressed substrates...
August 22, 2017: Journal of the Air & Waste Management Association
https://www.readbyqxmd.com/read/28799489/toward-enhancing-the-enzymatic-activity-of-a-novel-fungal-polygalacturonase-for-food-industry-optimization-and-biochemical-analyses
#9
Yousseria M H Shetaia, Ashraf F El-Baz, Ahmed M ElMekawy
BACKGROUND: The review of literature and patents shows that enhancing the PG production and activity are still required to fulfill the increasing demands. METHODS: A dual optimization process, which involved Plackett-Burman design (PBD), with seven factors, and response surface methodology, was applied to optimize the production of extracellular polygalacturonase (PG) enzyme produced by a novel strain of Aspergillus flavus isolated from rotten orange fruit. The fungal PG was purified and biochemically characterized...
August 11, 2017: Recent Patents on Biotechnology
https://www.readbyqxmd.com/read/28792360/in-their-own-words-a-qualitative-exploration-of-last-statements-of-capital-punishment-inmates-in-the-state-of-missouri-1995-2011
#10
Maranda A Upton, Tabitha M Carwile, Kristina S Brown
Last statements have been a common practice as part of capital punishment as far back as the 1300s in Europe. In the United States, the first execution occurred in 1608, and currently, 32 states have the death penalty. In 1991, Missouri integrated death row inmates into the general prison population, which makes this population unique compared with other death row populations across the United States. This article is a qualitative study on the themes found in the last statements of 46 capitally punished inmates in Missouri from 1995 to 2011...
September 2017: Omega
https://www.readbyqxmd.com/read/28769100/resistance-training-alone-reduces-systolic-and-diastolic-blood-pressure-in-prehypertensive-and-hypertensive-individuals-meta-analysis
#11
Evitom Corrêa de Sousa, Odilon Abrahin, Ana Lorena Lima Ferreira, Rejane Pequeno Rodrigues, Erik Artur Cortinhas Alves, Rodolfo Paula Vieira
The purpose of this study was to evaluate the effects of resistance training alone on the systolic and diastolic blood pressure in prehypertensive and hypertensive individuals. Our meta-analysis, followed the guidelines of PRISMA. The search for articles was realized by November 2016 using the following electronic databases: BIREME, PubMed, Cochrane Library, LILACS and SciELO and a search strategy that included the combination of titles of medical affairs and terms of free text to the key concepts: 'hypertension' 'hypertensive', 'prehypertensive', 'resistance training', 'strength training', and 'weight-lifting'...
November 2017: Hypertension Research: Official Journal of the Japanese Society of Hypertension
https://www.readbyqxmd.com/read/28665235/facial-feature-tracking-a-psychophysiological-measure-to-assess-exercise-intensity
#12
Kathleen H Miles, Bradley Clark, Julien D Périard, Roland Goecke, Kevin G Thompson
The primary aim of this study was to determine whether facial feature tracking reliably measures changes in facial movement across varying exercise intensities. Fifteen cyclists completed three, incremental intensity, cycling trials to exhaustion while their faces were recorded with video cameras. Facial feature tracking was found to be a moderately reliable measure of facial movement during incremental intensity cycling (intra-class correlation coefficient = 0.65-0.68). Facial movement (whole face (WF), upper face (UF), lower face (LF) and head movement (HM)) increased with exercise intensity, from lactate threshold one (LT1) until attainment of maximal aerobic power (MAP) (WF 3464 ± 3364mm, P < 0...
June 30, 2017: Journal of Sports Sciences
https://www.readbyqxmd.com/read/28653802/safety-profile-of-h1-antihistamines-in-pediatrics-an-analysis-based-on-data-from-vigibase
#13
Domenico Motola, Monia Donati, Chiara Biagi, Elisabetta Calamelli, Francesca Cipriani, Mauro Melis, Luca Monaco, Alberto Vaccheri, Giampaolo Ricci
PURPOSE: H1-antihistamines are commonly used in infants and children for the relief of histamine-mediated symptoms in a variety of conditions. Little is known about their safety profile in these patients. We performed a comparative analysis of the safety profiles of H1-antihistamines using data from the WHO database (VigiBase). METHODS: We selected adverse drug reaction (ADR) reports on H1-antihistamines in children (0-16 years) up to June 2014 from VigiBase. ADRs were codified according to MedDRA terminology...
October 2017: Pharmacoepidemiology and Drug Safety
https://www.readbyqxmd.com/read/28628565/open-versus-laparoscopic-surgery-for-advanced-low-rectal-cancer-a-large-multicenter-propensity-score-matched-cohort-study-in-japan
#14
Koya Hida, Ryosuke Okamura, Yoshiharu Sakai, Tsuyoshi Konishi, Tomonori Akagi, Tomohiro Yamaguchi, Takashi Akiyoshi, Meiki Fukuda, Seiichiro Yamamoto, Michio Yamamoto, Tatsuto Nishigori, Kenji Kawada, Suguru Hasegawa, Satoshi Morita, Masahiko Watanabe
BACKGROUND: Laparoscopic surgery for rectal cancer is widely performed all over the world and several randomized controlled trials have been reported. However, the usefulness of laparoscopic surgery compared with open surgery has not been demonstrated sufficiently, especially for the low rectal area. OBJECTIVE: The aim of this study was to investigate the hypothesis that laparoscopic primary tumor resection is safe and effective when compared with the open approach for locally advanced low rectal cancer...
June 16, 2017: Annals of Surgery
https://www.readbyqxmd.com/read/28573803/effect-of-socio-economic-status-on-sleep
#15
Won Hee Seo, Jung Hyun Kwon, So-Hee Eun, Gunha Kim, Kyungdo Han, Byung Min Choi
AIM: Sufficient sleep is an important factor in physical and mental health. Sleep duration can be affected by socio-economic status (SES). This study aimed to examine the association between sleep duration and SES in Korean adolescents. METHODS: This study was conducted with 1608 adolescents aged 12-18 years, based on data from the 2010 to 2012 Korean National Health and Nutrition Examination Survey (KNHANES). Sleep duration was self-reported in hours and three SES indicators were used: household income, basic livelihood security programmes and type of health insurance...
June 2017: Journal of Paediatrics and Child Health
https://www.readbyqxmd.com/read/28505513/polyfluoroalkyl-substance-exposure-in-the-mid-ohio-river-valley-1991-2012
#16
Robert L Herrick, Jeanette Buckholz, Frank M Biro, Antonia M Calafat, Xiaoyun Ye, Changchun Xie, Susan M Pinney
BACKGROUND: Industrial discharges of perfluorooctanoic acid (PFOA) to the Ohio River, contaminating water systems near Parkersburg, WV, were previously associated with nearby residents' serum PFOA concentrations above US general population medians. Ohio River PFOA concentrations downstream are elevated, suggesting Mid-Ohio River Valley residents are exposed through drinking water. OBJECTIVES: Quantify PFOA and 10 other per- and polyfluoroalkyl substances (PFAS) in Mid-Ohio River Valley resident sera collected between 1991 and 2013 and determine whether the Ohio River and Ohio River Aquifer are exposure sources...
September 2017: Environmental Pollution
https://www.readbyqxmd.com/read/28459136/pharmacokinetics-of-grapiprant-a-selective-ep4-prostaglandin-pge2-receptor-antagonist-after-2-mg-kg-oral-and-i-v-administrations-in-cats
#17
B Lebkowska-Wieruszewska, V De Vito, H Owen, A Poapholatep, M Giorgi
Drugs that provide effective analgesia in cats are limited. The aim of the study was to assess the pharmacokinetics of grapiprant after 2 mg/kg administration via p.o. and i.v. routes in cats. Six healthy adult cats were used according to an open, single-dose, two-treatment, two-period, randomized cross-over design. Cats were assigned to two treatment groups and administered with 2 mg/kg of grapiprant (pure powder) through p.o. and i.v. administration. Blood samples were collected at preassigned times and analysed by a validated HPLC method...
April 29, 2017: Journal of Veterinary Pharmacology and Therapeutics
https://www.readbyqxmd.com/read/28448761/sleeping-cupid-by-caravaggio-what-diagnosis
#18
Paolo Pozzilli, Marco Cappa
OBJECTIVE: The Sleeping Cupid, by Italian painter Caravaggio is a masterpiece painted in 1608. Signs of an endocrine disease are hidden among the shadows of the painting. We decided to conduct a survey among endocrinologists practicing in Italy and asked them if they could identify a specific disease condition in Caravaggio's Sleeping Cupid. METHODS: A total of 86 members from 2 Italian endocrine societies completed the survey: 67 from the Society of Endocrinology and 19 from the Society of Paediatric Endocrinology and Diabetology...
July 2017: Endocrine Practice
https://www.readbyqxmd.com/read/28389420/the-reviews-are-in-a-qualitative-content-analysis-of-consumer-perspectives-on-apps-for-bipolar-disorder
#19
Jennifer Nicholas, Andrea S Fogarty, Katherine Boydell, Helen Christensen
BACKGROUND: The delivery of mobile health (mHealth) services is acceptable to mental health consumers. However, despite the benefits of accessibility, cost-effectiveness, anonymity, and ability to tailor content to individual needs, consumer engagement remains a hurdle for uptake and continued use. This may be unsurprising as few studies have examined app content from the consumer perspective or assessed consumer preferences for the content of apps for mental health management. An opportunity to examine consumer perspectives exists in using naturally generated data that is publically available in the Google Play and Apple app stores...
April 7, 2017: Journal of Medical Internet Research
https://www.readbyqxmd.com/read/28343818/comparative-performances-of-serologic-and-molecular-assays-for-detecting-human-t-lymphotropic-virus-type-1-and-type-2-htlv-1-and-htlv-2-in-patients-infected-with-human-immunodeficiency-virus-type-1-hiv-1
#20
COMPARATIVE STUDY
Karoline Rodrigues Campos, Maria Gisele Gonçalves, Nadia Aparecida Costa, Adele Caterino-de-Araujo
The present study evaluated several techniques currently available (commercial kits and in-house assays) for diagnosing human T lymphotropic viruses types 1 and 2 in two groups of patients enrolled at HIV/AIDS specialized care services in São Paulo: Group 1 (G1), n=1608, 1237 male/371 female, median age 44.3 years old, majority using highly active antiretroviral therapy (HAART); G2, n=1383, 930 male/453 female, median age of 35.6 years old, majority HAART naïve. Enzyme immunoassays [(EIA) Murex and Gold ELISA] were employed for human T lymphotropic viruses types 1 and 2 screening; Western blotting (WB), INNO-LIA (LIA), real-time PCR pol (qPCR), and nested-PCR-RFLP (tax) were used to confirm infection...
May 2017: Brazilian Journal of Infectious Diseases
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