keyword
https://read.qxmd.com/read/38486274/correlation-analysis-between-occupational-stress-and-metabolic-syndrome-in-workers-of-a-petrochemical-enterprise-based-on-two-assessment-models-of-occupational-stress
#1
JOURNAL ARTICLE
Min Zhang, Bin Liu, Weiyi Ke, Yashi Cai, Lingyu Zhang, Weixu Huang, Xuehua Yan, Huifeng Chen
BACKGROUND: Occupational stress is becoming a common phenomenon around the world. Being in a high occupational stress state for a long time may destroy the metabolic balance of the body, thereby increasing the risk of metabolic diseases. There is limited evidence regarding the correlation between occupational stress and metabolic syndrome (MetS), particularly in the petrochemical workers. METHODS: A total of 1683 workers of a petrochemical enterprise in China were included in the survey by cluster sampling method...
March 14, 2024: BMC Public Health
https://read.qxmd.com/read/38471422/visible-light-activated-curcumin-doped-zinc-oxide-nanoparticles-integrated-into-orthodontic-adhesive-on-micro-tensile-bond-strength-degree-of-conversion-and-antibacterial-effectiveness-against-staphylococcus-aureus-an-investigation-using-scanning-electron-microscopy
#2
JOURNAL ARTICLE
Abdullah A Alnazeh, Muhammad Abdullah Kamran, Salem Almoammar, Mohammed Mohsen Al Jearah, Muhammad Qasim, Ibrahim Alshahrani
AIM: To acquire a thorough comprehension of the photoactivated Cur-doped ZnONPs at different concentrations 0%, 2.5%, and 5% on the physical qualities, antibacterial efficacy, degree of conversion, and μshear bond strength between orthodontic brackets and the enamel surface. MATERIAL AND METHODS: An extensive investigation was carried out utilizing a range of analytical methods, scanning electron microscopy (SEM) combined with energy-dispersive X-ray spectroscopy (EDX), Fourier-transform infrared (FTIR) spectroscopy, micro tensile bond strength (μTBS) testing, and evaluation of antibacterial effectiveness...
March 7, 2024: Journal of Photochemistry and Photobiology. B, Biology
https://read.qxmd.com/read/38468492/from-intestinal-metabolites-to-the-brain-investigating-the-mysteries-of-long-covid
#3
JOURNAL ARTICLE
Shan Liu, Ashwarya S Devason, Maayan Levy
No abstract text is available yet for this article.
March 2024: Clinical and Translational Medicine
https://read.qxmd.com/read/38459201/fermentation-of-rubus-dolichocarpus-juice-using-lactobacillus-gasseri-and-lacticaseibacillus-casei-and-protecting-phenolic-compounds-by-stevia-extract-during-cold-storage
#4
JOURNAL ARTICLE
Mohammad Mahdi Karimkhani, Abdollah Jamshidi, Mahmoud Nasrollahzadeh, Mohammad Armin, Seid Mahdi Jafari, Tayebeh Zeinali
This study aimed to investigate the biological activities of Lactobacillus gasseri SM 05 (L. gasseri) and Lacticaseibacillus casei subsp. casei PTCC 1608 (L. casei) in the black raspberry (Rubus dolichocarpus) juice (BRJ) environment, and also the anti-adhesion activity against Salmonella typhimurium (S. typhimurium) in fermented black raspberry juice (FBRJ). Results showed significant anti-adhesion activity in Caco-2 epithelial cells. In the anti-adhesion process, lactic acid bacteria (LAB) improve intestinal health by preventing the adhesion of pathogens...
March 8, 2024: Scientific Reports
https://read.qxmd.com/read/38414149/response-to-antisocial-personality-traits-relationship-with-behaviours-and-beliefs-on-covid-19-containment-measures-investigation-in-a-large-brazilian-sample
#5
JOURNAL ARTICLE
Lien-Chung Wei
No abstract text is available yet for this article.
February 27, 2024: Personality and Mental Health
https://read.qxmd.com/read/38397366/the-effect-of-sports-game-intervention-on-children-s-fundamental-motor-skills-a-systematic-review-and-meta-analysis
#6
REVIEW
Shengchuan Sun, Changzhou Chen
The purpose of the present study was to carry out a systematic review and a meta-analysis determining the effects of sports game intervention on fundamental motor skills in children. This paper presented a systematic review from 2001 to 2020, including the databases of Web of Science, EBSCO, Science, PubMed and Springer. (1) Participants comprised 1701 children age 3-12 years; (2) sports game interventions were investigated; (3) only studies using a Test of Gross Motor Skills assessment were included; (4) RCT were chosen as the study design to assess the impact of sports game interventions on children's motor skills; (5) only culture-based sports game studies in the English and Chinese language were included...
February 16, 2024: Children
https://read.qxmd.com/read/38359617/bidirectional-relationship-between-borderline-personality-features-and-depressive-symptoms-in-early-adolescence-a-school-based-cohort-study
#7
JOURNAL ARTICLE
Shaojie Wang, Lulu Fang, Yuan Li, Leilei Cao, Gengfu Wang, Juan Chen, Puyu Su
Depressive symptoms is a public health concern worldwide, and adolescents may experience more depressive symptoms. Although the relationship between borderline personality features (BPFs) disorder and depressive symptoms has been established, it is unclear whether the longitudinal relationship between them is unidirectional or bidirectional and whether these symptoms are different between boys and girls. In this study, Chinese adolescents (1608 total and separately 972 for boys and 636 girls) were enrolled between September 2019 and September 2021, and we analyzed the data using a cross-lagged model...
February 8, 2024: Journal of Psychiatric Research
https://read.qxmd.com/read/38350746/locally-advanced-pancreatic-cancer-is-surgical-palliation-associated-with-improved-clinical-outcome-relative-to-medical-palliation
#8
JOURNAL ARTICLE
Sarah P Kramer, Celsa Tonelli, Fred A Luchette, James Swanson, Zaid Abdelsattar, Tyler Cohn, Marshall S Baker
BACKGROUND: The value of palliative surgery in pancreatic cancer is not well-defined. METHODS: We queried the National Cancer Database for patients undergoing curative-intent resection, palliative surgery or medical palliation for clinical stage cT4N0-2M0 pancreatic cancer. Cohorts were 1:1:1 propensity-score-matched for comorbidities and stage. Kaplan-Meier method was used to compare overall survival for matched cohorts. RESULTS: 9,107 patients met inclusion criteria: 3,567 (39 ​%) underwent curative intent surgery, 1608 (18 ​%) surgical palliation, 3932 (43 ​%) medical palliation...
January 29, 2024: American Journal of Surgery
https://read.qxmd.com/read/38341753/hypoxic-mesenchymal-stem-cells-mscs-induced-interleukin-il-10-alleviate-systemic-lupus-erythematosus-sle-infl-ammation-through-inhibiting-interferon-ifn-gamma-production
#9
JOURNAL ARTICLE
Yan Wisnu Prajoko, Agung Putra, Ardi Prasetio, Nur Dina Amalina
Aim To determine the eff ect of hypoxic mesenchymal stem cells (MSCs) on the interleukin (IL)-10 and interferon (IFN)-gamma in peripheral blood mononuclear cells (PBMCs) from systemic lupus erythematosus (SLE) patients. Methods This study used a post-test control group design. Hypoxic MSCs were isolated and characterized according to their surface marker expression and diff erentiation capacities. PBMCs isolated from SLE patients were divided into three groups: control and two treatment groups. The treatment groups were treated by co-culturing MSCs to PBMCs with a ratio of 1:10 (T1) and 1:1 (T2) for 48 h incubation...
February 1, 2024: Medicinski Glasnik
https://read.qxmd.com/read/38339253/sargramostim-for-prophylactic-management-of-gastrointestinal-immune-related-adverse-events-of-immune-checkpoint-inhibitor-therapy-for-cancer
#10
REVIEW
Michael Dougan, Long H Nguyen, Elizabeth I Buchbinder, Hillard M Lazarus
Immune checkpoint inhibitor (ICI) therapy improves outcomes in several cancers. Unfortunately, many patients experience grade 3-4 treatment-related adverse events, including gastrointestinal (GI) toxicities which are common. These GI immune-related adverse events (irAEs) induced by ICIs present significant clinical challenges, require prompt intervention, and result in treatment delays or discontinuations. The treatment for these potentially severe and even fatal GI irAEs which include enterocolitis, severe diarrhea, and hepatitis may interfere with the anti-cancer approach...
January 24, 2024: Cancers
https://read.qxmd.com/read/38289669/natural-language-processing-of-referral-letters-for-machine-learning-based-triaging-of-patients-with-low-back-pain-to-the-most-appropriate-intervention-retrospective-study
#11
JOURNAL ARTICLE
Sebastian Fudickar, Carsten Bantel, Jannik Spieker, Heinrich Töpfer, Patrick Stegeman, Henrica R Schiphorst Preuper, Michiel F Reneman, André P Wolff, Remko Soer
BACKGROUND: Decision support systems (DSSs) for suggesting optimal treatments for individual patients with low back pain (LBP) are currently insufficiently accurate for clinical application. Most of the input provided to train these systems is based on patient-reported outcome measures. However, with the appearance of electronic health records (EHRs), additional qualitative data on reasons for referrals and patients' goals become available for DSSs. Currently, no decision support tools cover a wide range of biopsychosocial factors, including referral letter information to help clinicians triage patients to the optimal LBP treatment...
January 30, 2024: Journal of Medical Internet Research
https://read.qxmd.com/read/38275010/lgbtq-inequity-in-crowdfunding-cancer-costs-the-influence-of-online-reach-and-lgbtq-state-policy
#12
JOURNAL ARTICLE
Austin R Waters, Caleb W Easterly, Cindy Turner, Lauren Ghazal, Ida Tovar, Megan Mulvaney, Matt Poquadeck, Stephen A Rains, Kristin G Cloyes, Anne C Kirchhoff, Erin E Kent, Echo L Warner
BACKGROUND: Emerging literature suggests that LGBTQ+ cancer survivors are more likely to experience financial burden than non-LGBTQ+ survivors. However, LGBTQ+ cancer survivors experience with cost-coping behaviors such as crowdfunding is understudied. METHODS: We aimed to assess LGBTQ+ inequity in cancer crowdfunding by combining community-engaged and technology-based methods. Crowdfunding campaigns were web-scraped from GoFundMe and classified as cancer-related and LGBTQ+ or non-LGBTQ+ using term dictionaries...
January 26, 2024: Cancer Medicine
https://read.qxmd.com/read/38261024/evaluation-of-fresh-scores-in-predicting-outcome-and-quality-of-life-after-aneurysmal-subarachnoid-haemorrhage-in-a-european-patient-cohort
#13
JOURNAL ARTICLE
Björn B Hofmann, Evgenia P Gundlach, Igor Fischer, Sajjad Muhammad, Rainer Kram, Kerim Beseoglu, Jan F Cornelius
BACKGROUND: Despite aneurysmal subarachnoid haemorrhage (aSAH) patients often experiencing physical and mental disabilities impacting their quality of life (QoL), routine assessment of long-term QoL data and predictive tools are limited. This study evaluates the newly developed "functional recovery expected after subarachnoid haemorrhage" (FRESH) scores with long-term outcomes and QoL in European aSAH patients. METHODS: FRESH, FRESH-cog, and FRESH-quol scores were retrospectively obtained from aSAH patients...
January 23, 2024: Acta Neurochirurgica
https://read.qxmd.com/read/38241321/impact-of-three-dimensional-reconstruction-visualization-technology-on-short-and-long-term-outcomes-after-hepatectomy-in-patients-with-hepatocellular-carcinoma-a-propensity-score-matched-and-inverse-probability-of-treatment-weighted-multicenter-study
#14
JOURNAL ARTICLE
Xiaojun Zeng, Haisu Tao, Yanchen Dong, Yuwei Zhang, Junying Yang, Feichao Xuan, Jian Zhou, Weidong Jia, Jingfeng Liu, Chaoliu Dai, Haoyu Hu, Nan Xiang, Ning Zeng, Weiping Zhou, Wanyee Lau, Jian Yang, Chihua Fang
BACKGROUND: Three-dimensional reconstructive visualization (3D-RVT) is an important tool in the preoperative assessment of patients undergoing liver resection. However, it is not clear whether this technique can improve short- and long-term outcomes in patients with hepatocellular carcinoma compared with two-dimensional (2D) imaging. METHOD: A total of 3402 patients from five centers were consecutively enrolled from January 2016 to December 2020, and grouped based on the use of 3D-RVT or 2D imaging for preoperative assessment...
January 19, 2024: International Journal of Surgery
https://read.qxmd.com/read/38199995/defining-the-biogeographical-map-and-potential-bacterial-translocation-of-microbiome-in-human-surface-organs
#15
JOURNAL ARTICLE
Jun-Jun She, Wei-Xin Liu, Xiao-Ming Ding, Gang Guo, Jing Han, Fei-Yu Shi, Harry Cheuk-Hay Lau, Chen-Guang Ding, Wu-Jun Xue, Wen Shi, Gai-Xia Liu, Zhe Zhang, Chen-Hao Hu, Yinnan Chen, Chi Chun Wong, Jun Yu
The microbiome in a specific human organ has been well-studied, but few reports have investigated the multi-organ microbiome as a whole. Here, we aim to analyse the intra-individual inter-organ and intra-organ microbiome in deceased humans. We collected 1608 samples from 53 sites of 7 surface organs (oral cavity, esophagus, stomach, small intestine, appendix, large intestine and skin; n = 33 subjects) and performed microbiome profiling, including 16S full-length sequencing. Microbial diversity varied dramatically among organs, and core microbial species co-existed in different intra-individual organs...
January 10, 2024: Nature Communications
https://read.qxmd.com/read/38159337/zotiraciclib-tg02-for-newly-diagnosed-glioblastoma-in-the-elderly-or-for-recurrent-glioblastoma-the-eortc-1608-steam-trial
#16
JOURNAL ARTICLE
Emilie Le Rhun, Thierry Gorlia, Jörg Felsberg, Joost Jongen, Claude-Alain Maurage, François Ducray, Dorothee Gramatzki, Peter Hau, Olivier L Chinot, Matthias Preusser, Stephanie Cartalat, Patrick Roth, Martin van den Bent, Julia Furtner, Maike Collienne, Guido Reifenberger, Michael Weller
BACKGROUND: Zotiraciclib (TG02) is an oral multi-cyclin dependent kinase (CDK) inhibitor thought to inhibit tumor growth via CDK-9-dependent depletion of survival proteins such as c-MYC and MCL-1 which are frequently overexpressed in glioblastoma. METHODS: EORTC 1608 (NCT03224104) (STEAM) had a three parallel group (A,B,C) phase Ib, open-label, non-randomized, multicenter design in IDH wild-type newly diagnosed glioblastoma or anaplastic astrocytoma. Groups A and B explored the maximum tolerated dose (MTD) of TG02 in elderly patients, in combination with hypofractionated radiotherapy alone (group A) or temozolomide alone (group B), according to O6 -methylguanine DNA methyltransferase promoter methylation status determined centrally...
December 18, 2023: European Journal of Cancer
https://read.qxmd.com/read/38137802/complement-and-non-complement-binding-anti-hla-antibodies-are-differentially-detected-with-different-antigen-bead-assays-in-renal-transplant-recipients
#17
JOURNAL ARTICLE
Konstantinos Ouranos, Manolis Panteli, Georgios Petasis, Marianthi Papachristou, Artemis Maria Iosifidou, Myrto Aikaterini Iosifidou, Aikaterini Anastasiou, Margarita Samali, Maria Stangou, Ioannis Theodorou, Georgios Lioulios, Asimina Fylaktou
Two semi-quantitative, Luminex-based, single-antigen bead (SAB) assays are available to detect anti-HLA antibodies and evaluate their reactivity with complement binding. Sera from 97 patients with positive panel reactive antibody tests (>5%) were analyzed with two SAB tests, Immucor (IC) and One-Lambda (OL), for anti-HLA antibody detection and the evaluation of their complement-binding capacity. IC detected 1608/8148 (mean fluorescent intensity (MFI) 4195 (1995-11,272)) and 1136/7275 (MFI 6706 (2647-13,184)) positive anti-HLA class I and II specificities, respectively...
December 17, 2023: Journal of Clinical Medicine
https://read.qxmd.com/read/38114409/covid-19-vaccine-effectiveness-against-severe-covid-19-requiring-oxygen-therapy-invasive-mechanical-ventilation-and-death-in-japan-a-multicenter-case-control-study-motivate-study
#18
MULTICENTER STUDY
Takeshi Arashiro, Maki Miwa, Hidenori Nakagawa, Junpei Takamatsu, Kunihiro Oba, Satoshi Fujimi, Hitoshi Kikuchi, Takamasa Iwasawa, Fumiko Kanbe, Keisuke Oyama, Masayuki Kanai, Yoshitaka Ogata, Takanori Asakura, Takahiro Asami, Keiko Mizuno, Manabu Sugita, Torahiko Jinta, Yusuke Nishida, Hideaki Kato, Kazuaki Atagi, Taiki Higaki, Yoshio Nakano, Takeya Tsutsumi, Kent Doi, Shu Okugawa, Akihiro Ueda, Akira Nakamura, Toru Yoshida, Kaoru Shimada-Sammori, Keiki Shimizu, Yasuo Fujita, Yasumi Okochi, Kentaro Tochitani, Asuka Nakanishi, Hiroshi Rinka, Daisuke Taniyama, Asase Yamaguchi, Toshio Uchikura, Maiko Matsunaga, Hiromi Aono, Masanari Hamaguchi, Kentaro Motoda, Sohei Nakayama, Kei Yamamoto, Hideaki Oka, Katsushi Tanaka, Takeshi Inoue, Mieko Kobayashi, Shigeki Fujitani, Maki Tsukahara, Saki Takeda, Ashley Stucky, Tadaki Suzuki, Chris Smith, Martin Hibberd, Koya Ariyoshi, Yuji Fujino, Yuzo Arima, Shinhiro Takeda, Satoru Hashimoto, Motoi Suzuki
INTRODUCTION: Since the SARS-CoV-2 Omicron variant became dominant, assessing COVID-19 vaccine effectiveness (VE) against severe disease using hospitalization as an outcome became more challenging due to incidental infections via admission screening and variable admission criteria, resulting in a wide range of estimates. To address this, the World Health Organization (WHO) guidance recommends the use of outcomes that are more specific to severe pneumonia such as oxygen use and mechanical ventilation...
January 25, 2024: Vaccine
https://read.qxmd.com/read/38113936/effects-of-environmental-translocation-and-host-characteristics-on-skin-microbiomes-of-sun-basking-fish
#19
JOURNAL ARTICLE
Hanna Berggren, Oscar Nordahl, Yeşerin Yıldırım, Per Larsson, Petter Tibblin, Anders Forsman
Variation in the composition of skin-associated microbiomes has been attributed to host species, geographical location and habitat, but the role of intraspecific phenotypic variation among host individuals remains elusive. We explored if and how host environment and different phenotypic traits were associated with microbiome composition. We conducted repeated sampling of dorsal and ventral skin microbiomes of carp individuals ( Cyprinus carpio ) before and after translocation from laboratory conditions to a semi-natural environment...
December 20, 2023: Proceedings. Biological Sciences
https://read.qxmd.com/read/38107108/quinoa-dough-fermentation-by-saccharomyces-cerevisiae-and-lactic-acid-bacteria-changes-in-saponin-phytic-acid-content-and-antioxidant-capacity
#20
JOURNAL ARTICLE
Sanaz Arjmand, Neda Mollakhalili-Meybodi, Fateme Akrami Mohajeri, Farzan Madadizadeh, Elham Khalili Sadrabad
The effects of two fermentation processes (common fermentation with Saccharomyces cerevisiae and fermentation by Lacticaseibacillus casei subsp. casei PTCC 1608 and Lactiplantibacillus plantarum subsp. plantarum PTCC 1745) on pH, titratable acidity, total phenolic and flavonoid contents, antioxidant capacity, saponin content, as well as phytic acid content of quinoa dough were investigated during the 24-h fermentation (4-h interval). According to the results, the highest titratable acidity was observed in the samples fermented by L...
December 2023: Food Science & Nutrition
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