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https://www.readbyqxmd.com/read/29691570/-outcome-of-one-visit-and-multiple-visit-root-canal-treatment-for-cracked-tooth-with-pulpitis-a-meta-analysis
#1
Wen Wang, Peng-Lai Wang, Ni-Na Xie, Cui Wu, Zong-Xiang Liu
PURPOSE: To compare the treatment effect between one-visit and multiple-visit endodontic treatment for cracked tooth with pulpitis. METHODS: The literatures published before 2016-06-01 regarding to one-visit and multiple-visit root canal treatment for cracked tooth with pulpitis were searched through MEDLINE, CNKI, VIP, Wanfang Database et al. Then the included studies were chosen according to the inclusion criteria. Collection of features, quality evaluation and analysis of treatment effect, follow-up results (half year/1 year) and postoperative pain of the included studies were analyzed using Stata/SE12...
December 2017: Shanghai Kou Qiang Yi Xue, Shanghai Journal of Stomatology
https://www.readbyqxmd.com/read/29606472/application-of-an-advanced-and-wide-scope-non-target-screening-workflow-with-lc-esi-qtof-ms-and-chemometrics-for-the-classification-of-the-greek-olive-oil-varieties
#2
Natasa P Kalogiouri, Reza Aalizadeh, Nikolaos S Thomaidis
An optimized and validated LC-ESI-QTOF-MS method with an integrated non-target screening workflow was applied in the investigation of the metabolomic profile of 51 Greek monovarietal extra virgin olive oils (EVOOs) from the varieties: Manaki, Ladoelia, Koroneiki, Amfissis, Chalkidikis and Kolovi. Data processing was carried out with the R language and XCMS package. A local database consisting of 1608 compounds naturally occurring in different organs of Olea Europa L. was compiled in order to accelerate the identification workflow...
August 1, 2018: Food Chemistry
https://www.readbyqxmd.com/read/29603405/short-and-long-term-cost-and-utilization-of-health-care-resources-in-parkinson-s-disease-in-the-uk
#3
Sharada Weir, Mihail Samnaliev, Tzu-Chun Kuo, Travis S Tierney, Silke Walleser Autiero, Rod S Taylor, Anette Schrag
BACKGROUND: There is currently no robust long-term data on costs of treating patients with Parkinson's disease. The objective of this study was to report levels of health care utilization and associated costs in the 10 years after diagnosis among PD patients in the United Kingdom. METHODS: We undertook a retrospective population-based cohort study using linked data from the UK Clinical Practice Research Datalink and Hospital Episode Statistics databases. Total health care costs of PD patients were compared with those of a control group of patients without PD selected using 1:1 propensity score matching based on age, sex, and comorbidity...
March 30, 2018: Movement Disorders: Official Journal of the Movement Disorder Society
https://www.readbyqxmd.com/read/29599752/transcriptional-response-of-staphylococcus-aureus-to-sunlight-in-oxic-and-anoxic-conditions
#4
Jill S McClary, Alexandria B Boehm
The transcriptional response of Staphylococcus aureus strain Newman to sunlight exposure was investigated under both oxic and anoxic conditions using RNA sequencing to gain insight into potential mechanisms of inactivation. S. aureus is a pathogenic bacterium detected at recreational beaches which can cause gastrointestinal illness and skin infections, and is of increasing public health concern. To investigate the S. aureus photostress response in oligotrophic seawater, S. aureus cultures were suspended in seawater and exposed to full spectrum simulated sunlight...
2018: Frontiers in Microbiology
https://www.readbyqxmd.com/read/29534836/global-budget-revenue-on-a-single-institution-s-costs-and-outcomes-in-patients-undergoing-total-hip-arthroplasty
#5
Ronald E Delanois, Chukwuweike U Gwam, Jeffrey J Cherian, Jennifer I Etcheson, Nicole E George, Kathleen A Schneider, Michael A Mont
BACKGROUND: The state of Maryland was granted a waiver by the Center for Medicare and Medicaid Services to implement a Global Budget Revenue (GBR) reimbursement model. This study aims to compare (1) costs of inpatient hospital stays; (2) postacute care costs; (3) lengths of stay (LOS); and (4) discharge disposition who underwent primary total hip arthroplasty at a single Maryland-based orthopedic institution before and after the implementation of GBR. METHODS: The Maryland Center for Medicare and Medicaid Services database was queried to obtain all Medicare patients who underwent total hip arthroplasty at a single institution before and after the implementation of GBR...
February 15, 2018: Journal of Arthroplasty
https://www.readbyqxmd.com/read/29516934/patterns-of-tobacco-use-in-patients-with-upper-aero-digestive-tract-cancers-a-hospital-based-study
#6
Amal Chandra Kataki, Jagannath Dev Sharma, Manigreeva Krishnatreya, Nizara Baishya, Manoj Kalita
Background: Tobacco use is a major risk factor for increasing the burden of upper aero digestive tract (UADT) cancer in the population of Northeast India. Objective: The objective of this study was to investigate the pattern of tobacco use in different UADT cancer. Materials and Methods: This was a retrospective study of electronically recorded data of the Hospital Cancer Registry for the period of May 2014 to December 2014. The UADT cancers were evaluated for gender and age-group distribution, their relative proportion, and association with tobacco use and tobacco-associated risk in males to develop UADT cancers...
January 2018: Journal of Cancer Research and Therapeutics
https://www.readbyqxmd.com/read/29471789/melanin-embedded-materials-effectively-remove-hexavalent-chromium-cr-vi-from-aqueous-solution
#7
An Manh Cuong, Nguyen Thi Le Na, Pham Nhat Thang, Trinh Ngoc Diep, Ly Bich Thuy, Nguyen Lai Thanh, Nguyen Dinh Thang
BACKGROUND: Currently, it is recognized that water polluted with toxic heavy metal ions may cause serious effects on human health. Therefore, the development of new materials for effective removal of heavy metal ions from water is still a widely important area. Melanin is being considered as a potential material for removal of heavy metal from water. METHODS: In this study, we synthesized two melanin-embedded beads from two different melanin powder sources and named IMB (Isolated Melanin Bead originated from squid ink sac) and CMB (Commercial Melanin Bead originated from sesame seeds)...
February 23, 2018: Environmental Health and Preventive Medicine
https://www.readbyqxmd.com/read/29470809/receiving-hiv-serostatus-disclosure-from-partners-before-sex-results-from-an-online-survey-of-chinese-men-who-have-sex-with-men
#8
Weiming Tang, Chuncheng Liu, Bolin Cao, Stephen W Pan, Ye Zhang, Jason Ong, Hongyun Fu, Baoli Ma, Rong Fu, Bin Yang, Wei Ma, Chongyi Wei, Joseph D Tucker
HIV serostatus disclosure before sex can facilitate serosorting, condom use and potentially decrease the risk of HIV acquisition. However, few studies have evaluated HIV serostatus disclosure from partners before sex. We examined the rate and correlates of receiving HIV serostatus disclosure from regular and casual male partners before sex among an online sample of men who have sex with men (MSM) in China. An online cross-sectional study was conducted among MSM in eight Chinese cities in July 2016. Participants completed questions covering sociodemographic information, sexual behaviors, HIV testing (including HIV self-testing) history, self-reported HIV status, and post-test violence...
February 22, 2018: AIDS and Behavior
https://www.readbyqxmd.com/read/29440123/portrait-patient-centered-outcomes-related-to-treatment-practices-in-peripheral-arterial-disease-investigating-trajectories-overview-of-design-and-rationale-of-an-international-prospective-peripheral-arterial-disease-study
#9
REVIEW
Kim G Smolderen, Kensey Gosch, Manesh Patel, W Schuyler Jones, Alan T Hirsch, John Beltrame, Rob Fitridge, Mehdi H Shishehbor, Johan Denollet, Patrick Vriens, Jan Heyligers, Nancy Stone MEd, Herbert Aronow, J Dawn Abbott, Clementine Labrosciano, Rudolf Tutein-Nolthenius, John A Spertus
BACKGROUND: Health status outcomes, including symptoms, functional status, and quality of life, are critically important outcomes from patients' perspectives. The PORTRAIT study (Patient-Centered Outcomes Related to Treatment Practices in Peripheral Arterial Disease: Investigating Trajectories) was designed to prospectively define health status outcomes and examine associations between patients' characteristics and care to these outcomes among those presenting with new-onset or worsened claudication...
February 2018: Circulation. Cardiovascular Quality and Outcomes
https://www.readbyqxmd.com/read/29417430/effect-of-discontinuation-or-initiation-of-methotrexate-or-glucocorticoids-on-tofacitinib-efficacy-in-patients-with-rheumatoid-arthritis-a-post-hoc-analysis
#10
Roy Fleischmann, Jürgen Wollenhaupt, Stanley Cohen, Lisy Wang, Haiyun Fan, Vara Bandi, John Andrews, Liza Takiya, Eustratios Bananis, Michael E Weinblatt
INTRODUCTION: Tofacitinib is an oral Janus kinase inhibitor for the treatment of rheumatoid arthritis (RA). We evaluated the effect of concomitant methotrexate (MTX) or glucocorticoid (GC) use on tofacitinib clinical efficacy. METHODS: Data were pooled from two open-label, long-term extension studies of tofacitinib 5 or 10 mg twice daily in patients with RA. Response according to Clinical Disease Activity Index (CDAI) was assessed separately in patients who discontinued (no MTX/GC use within 30 days prior to year-3 visit; assessment at month 3/year 3) or initiated (on/before year 3; assessment at initiation and year 3) MTX/GC...
February 7, 2018: Rheumatology and Therapy
https://www.readbyqxmd.com/read/29415831/evaluation-of-a-short-protocol-for-indirect-calorimetry-in-females-with-eating-disorders-and-healthy-controls
#11
Therese Fostervold Mathisen, Kethe Marie Engen, Jorunn Sundgot-Borgen, Trine Stensrud
BACKGROUND AND AIMS: To enable clinicians to identify the clinical picture and treatment progress and to adjust eating plans according to personal energy needs, it is important to know the patient's correct resting metabolic rate (RMR). Indirect calorimetry (IC) is the preferred method for assessment of RMR, but long duration of measurement increases the load on the patients, and reduces the effectiveness in clinical and scientific settings. Further; not all patients reach a valid RMR according to the suggested best practice protocol, with 5 min of steady state (SS) where respiratory gas volume exchange varies less than 10%...
December 2017: Clinical Nutrition ESPEN
https://www.readbyqxmd.com/read/29415248/alcohol-use-among-norwegian-workers-associations-with-health-and-well-being
#12
M B Nielsen, J Gjerstad, M Frone
Background: There is a lack of published data on the association between alcohol consumption and health and well-being in working populations. Aims: To determine how levels of alcohol consumption are associated with psychological distress, somatic complaints, sleep and job satisfaction in the Norwegian workforce. Methods: Survey questionnaire data from a probability sample comprising Norwegian employees. The association between alcohol consumption and health and well-being was assessed using analysis of covariance...
March 27, 2018: Occupational Medicine
https://www.readbyqxmd.com/read/29407611/functional-characterization-of-tumor-necrosis-factor-receptor-associated-factor-3-of-sea-perch-lateolabrax-japonicas-in-innate-immune
#13
Wanwan Zhang, Peng Jia, Wei Liu, Yunlong Li, Meisheng Yi, Kuntong Jia
Tumor necrosis factor receptor-associated factor 3 (TRAF3) is a multifunctional regulator implicated in both bacterial defense and antiviral immunity. Here, a TRAF3 gene from the seawater fish sea perch, designated as LjTRAF3, was characterized. The full-length cDNA of LjTRAF3 was 2972 bp including a 5' untranslated region (UTR) of 243 bp, a 3'UTR of 941 bp and a putative open reading frame of 1608 bp encoding a putative protein of 536 amino acid. The deduced LjTRAF3 protein contained a RING finger, two zinc fingers, a coiled-coil, and a meprin and TRAF-C homology domain...
April 2018: Fish & Shellfish Immunology
https://www.readbyqxmd.com/read/29372458/-1-h-15-n-and-13-c-resonance-assignments-of-the-third-domain-from-the-s-aureus-innate-immune-evasion-protein-eap
#14
Alvaro I Herrera, Nicoleta T Ploscariu, Brian V Geisbrecht, Om Prakash
Staphylococcus aureus is a widespread and persistent pathogen of humans and livestock. The bacterium expresses a wide variety of virulence proteins, many of which serve to disrupt the host's innate immune system from recognizing and clearing bacteria with optimal efficiency. The extracellular adherence protein (Eap) is a multidomain protein that participates in various protein-protein interactions that inhibit the innate immune response, including both the complement system (Woehl et al in J Immunol 193:6161-6171, 2014) and Neutrophil Serine Proteases (NSPs) (Stapels et al in Proc Natl Acad Sci USA 111:13187-13192, 2014)...
April 2018: Biomolecular NMR Assignments
https://www.readbyqxmd.com/read/29299622/a-novel-galactolipase-from-a-green-microalga-chlorella-kessleri-purification-characterization-molecular-cloning-and-heterologous-expression
#15
Shuhei Hashiro, Koyu Fujiuchi, Daisuke Sugimori, Hisashi Yasueda
We have identified an enzyme, galactolipase (ckGL), which hydrolyzes the acyl ester bond of galactolipids such as digalactosyldiacylglycerol (DGDG), in the microalga Chlorella kessleri. Following purification of the enzyme to electrophoretic homogeneity from cell-free extract, the maximum activity toward DGDG was observed at pH 6.5 and 37 °C. ckGL was Ca2+ -dependent enzyme and displayed an apparent molecular mass of approx. 53 kDa on SDS-PAGE. The substrate specificity was in the order: DGDG (100%) > monogalactosyldiacylglycerol ≈ phosphatidylglycerol (~ 40%) > sulfoquinovosyldiacylglycerol (~ 20%); the enzyme exhibited almost no activity toward glycerides and other phospholipids...
February 2018: Applied Microbiology and Biotechnology
https://www.readbyqxmd.com/read/29170300/3-derivation-and-internal-validation-of-a-clinical-decision-rule-to-guide-whole-body-computed-tomography-scanning-in-trauma
#16
Hridesh Chatha, Ian Sammy, Rick Body, Abdo Sattout, John Hollingsworth
BACKGROUND: There are no widely accepted validated clinical decision rules for the use of WBCT in trauma. Given the potential risks and costs, there is a clear need for a clinical decision rule (CDR) to safely guide targeted use of WBCT. We aimed to derive a CDR to guide clinical decisions on WBCT utilisation by detecting patients at high and low risk of multi-region trauma. METHODS: We retrospectively identified consecutive patients who had presented to a major trauma centre with suspected major trauma...
December 2017: Emergency Medicine Journal: EMJ
https://www.readbyqxmd.com/read/29141287/-observation-of-systemic-adverse-reactions-by-specific-immunotherapy-and-analysis-of-risk-factors-in-allergic-rhinitis
#17
Y Shen, S L Hong, M Zhang, X Ke
Objective: To investigate the systemic adverse effects of specific subcutaneous immunotherapy (SCIT) in patients with allergic rhinitis (AR) and explore the possible risk factors. Methods: A retrospective study was conducted on AR patients who underwent SCIT from January 2014 to January 2017 in Department of Otorhinolaryngology, the First Affiliated Hospital of Chongqing Medical University. For patients with adverse reactions, the detailed medical history during treatment was reviewed. Results: A total of 1608 injections were performed on 102 patients, there were 12 cases / 21 times systemic adverse events, including systemic urticaria, angioedema and Grade Ⅰ systemic adverse reactions...
November 7, 2017: Zhonghua Er Bi Yan Hou Tou Jing Wai Ke za Zhi, Chinese Journal of Otorhinolaryngology Head and Neck Surgery
https://www.readbyqxmd.com/read/29136023/modifications-of-hemoglobin-and-myoglobin-by-maillard-reaction-products-mrps
#18
Aristos Ioannou, Constantinos Varotsis
High performance liquid chromatography (HPLC) coupled with a Fraction Collector was employed to isolate Maillard reaction products (MRPs) formed in model systems comprising of asparagine and monosaccharides in the 60-180°C range. The primary MRP which is detected at 60°C is important for Acrylamide content and color/aroma development in foods and also in the field of food biotechnology for controlling the extent of the Maillard reaction with temperature. The discrete fractions of the reaction products were reacted with Hemoglobin (Hb) and Myoglobin (Mb) at physiological conditions and the reaction adducts were monitored by UV-vis and Attenuated Total Reflection-Fourier transform infrared (FTIR) spectrophotometry...
2017: PloS One
https://www.readbyqxmd.com/read/29129761/are-antiplatelet-and-anticoagulants-drugs-a-risk-factor-for-bleeding-in-mild-traumatic-brain-injury
#19
Laura Uccella, Cesare Zoia, Daniele Bongetta, Paolo Gaetani, Franz Martig, Christian Candrian, Raffaele Rosso
OBJECTIVE: Facing mild traumatic brain injury, clinicians must decide whether to perform a computed tomography (CT) scan to detect a potential intracranial hemorrhage. Many useful guidelines have been developed for the general population, but there is no general consensus about the best practice to adopt when dealing with patients on antiplatelet or anticoagulation drugs. The relatively recent introduction of new anticoagulants and second-generation antiplatelet drugs poses new challenges in this field...
February 2018: World Neurosurgery
https://www.readbyqxmd.com/read/29094330/the-association-between-elevated-serum-uric-acid-level-and-an-increased-risk-of-renal-function-decline-in-a-health-checkup-cohort-in-china
#20
Xia Cao, Liuxin Wu, Zhiheng Chen
PURPOSE: To investigate whether an elevated serum uric acid (SUA) level is an independent risk factor for rapid decline in renal function or new-onset chronic kidney disease (CKD) in a Chinese health checkup population. METHODS: A cohort study of 6495 Chinese individuals who underwent health checkups with normal estimated glomerular filtration rate (eGFR) at baseline was carried out from May 2011 to April 2016. Examinations included a questionnaire, physical measurements, and blood sampling...
March 2018: International Urology and Nephrology
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