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THERAPEUTIC EUS

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https://www.readbyqxmd.com/read/29665210/endoscopic-ultrasound-diagnosis-of-merkel-cell-carcinoma-metastasizing-to-pancreas
#1
Juliana Pinho, Diana Montezuma, Paula Monteiro, Mário Dinis-Ribeiro, Pedro Bastos
Merkel cell carcinoma (MCC) is a rare and aggressive primary neuroendocrine tumor of the skin, with a high propensity for local, regional and distant spread1 . However, distant metastasis of MCC to the pancreas are rarely seen. EUS-FNA is an effective tool in the evaluation and differential diagnosis of pancreatic mass lesions3 . Differentiating metastatic pancreatic tumors, especially Merkel cell carcinoma, from primary pancreatic tumor will influence clinical management and therapeutic strategies2 . This article is protected by copyright...
April 17, 2018: Cytopathology: Official Journal of the British Society for Clinical Cytology
https://www.readbyqxmd.com/read/29611112/sedation-practices-in-gastrointestinal-endoscopy-a-survey-from-southern-india
#2
Prakash Zacharias, Shibi Mathew, John Mathews, Aby Somu, Maya Peethambaran, Menon Prashanth, Mathew Philip
Gastrointestinal endoscopies can cause an unpleasant experience for the patient. In India, most endoscopists follow a common institutional policy for sedation. The aim of this study was to analyze the sedation practices in various endoscopy centers across southern India. Data were collected with the help of a structured questionnaire given to a senior endoscopist of the center. Data from the completed questionnaire were later analyzed. Data were obtained from 19 centers across southern India. All endoscopy suites had central oxygen supply and emergency cart...
April 3, 2018: Indian Journal of Gastroenterology: Official Journal of the Indian Society of Gastroenterology
https://www.readbyqxmd.com/read/29560509/light-rescues-circadian-behavior-and-brain-dopamine-abnormalities-in-diurnal-rodents-exposed-to-a-winter-like-photoperiod
#3
Jacob Itzhacki, Daniel Clesse, Yannick Goumon, Eus J Van Someren, Jorge Mendoza
Seasonal affective disorder (SAD), beyond mood changes, is characterized by alterations in daily rhythms of behavior and physiology. The pathophysiological conditions of SAD involve changes in day length and its first-line treatment is bright light therapy. Animal models using nocturnal rodents have been studied to elucidate the neurobiological mechanisms of depression, but might be ill suited to study the therapeutic effects of light in SAD since they exhibit light-aversive responses. Here Arvicanthis ansorgei, a diurnal rodent, was used to determine behavioral, molecular and brain dopamine changes in response to exposure to a winter-like photoperiod consisting of a light-dark cycle with 8 h of light, under diminished light intensity, and 16 h of darkness...
March 20, 2018: Brain Structure & Function
https://www.readbyqxmd.com/read/29525455/transluminal-approach-with-bubble-seeded-histotripsy-for-cancer-treatment-with-ultrasonic-mechanical-effects
#4
Reiko Ashida, Ken-Ichi Kawabata, Takashi Maruoka, Kazuhiro Yamanaka, Hideki Yoshikawa, Tatsuya Ioka, Kazuhiro Katayama, Sachiko Tanaka
Bubble-seeded histotripsy (BSH) is a newly developed ultrasound-based mechanical fractionation technique using locally injected phase change nanodroplets (PCNDs) as sensitizers. The PCNDs are a kind of microbubble precursor compressed into submicron-size in droplets form, which were designed for local administration and will expand into microbubbles under ultrasound exposure. Previously, we reported that a combination of PCNDs injection and pulsed high-intensity focused ultrasound (pHIFU) with an acoustic intensity as low as about 3 kW/cm2 at 1...
March 7, 2018: Ultrasound in Medicine & Biology
https://www.readbyqxmd.com/read/29458153/eus-guided-transluminal-interventions
#5
Uzma D Siddiqui, Michael J Levy
The role of endoscopic ultrasound (EUS) has transitioned from a diagnostic to a therapeutic one over the past 40 years. With the advent of curvilinear array echoendoscopes in the 1990's with an accessory channel, multiple tools and devices have been developed and utilized for a variety of transluminal interventions. EUS provides a viable option and is becoming the procedure of choice for many interventions including bile and pancreatic duct drainage, guiding angiotherapy, pancreatic fluid collection management, gallbladder drainage, and creating a gastrojejunostomy...
February 16, 2018: Gastroenterology
https://www.readbyqxmd.com/read/29454788/advances-and-challenges-in-endoscopic-training
#6
Kevin A Waschke, Walter Coyle
One of the challenges of the current era is ensuring that endoscopic training is accomplished effectively in the face of multiple competing demands. As health care delivery evolves, with rising patient complexity and increasing productivity requirements, there is mounting pressure on the time available for training in the clinical setting. The practice of endoscopy itself continues to expand to include increasingly complex procedures (eg, therapeutic endoscopic ultrasound, endoscopic submucosal dissection, and peroral endoscopic myotomy) that require dedicated endoscopy training...
February 15, 2018: Gastroenterology
https://www.readbyqxmd.com/read/29452076/feasibility-of-eus-guided-nd-yag-laser-ablation-of-unresectable-pancreatic-adenocarcinoma
#7
Francesco Maria Di Matteo, Paola Saccomandi, Margareth Martino, Monica Pandolfi, Margherita Pizzicannella, Valerio Balassone, Emiliano Schena, Claudio Marcello Pacella, Sergio Silvestri, Guido Costamagna
BACKGROUND AND AIMS: Endoscopic ultrasound (EUS) has become an interventional technique in which a needle may be used as a vehicle to deliver therapeutic agents. Laser ablation (LA) has been used to treat many primary and secondary neoplasms. This study aimed to assess the feasibility of EUS-guided LA for unresectable (UR) pancreatic cancer. METHODS: Patients with a stage IIb-III pancreatic cancer underwent EUS-guided LA. All patients were unresponsive to previous chemo-radiotherapy...
February 13, 2018: Gastrointestinal Endoscopy
https://www.readbyqxmd.com/read/29426291/paediatric-pancreaticobiliary-endoscopy-a-21-year-experience-from-a-tertiary-hepatobiliary-centre-and-systematic-literature-review
#8
Margaret G Keane, Mayur Kumar, Natascha Cieplik, Douglas Thorburn, Gavin J Johnson, George J Webster, Michael H Chapman, Keith J Lindley, Stephen P Pereira
BACKGROUND: In adults ERCP and endoscopic ultrasound (EUS) are standard methods of evaluating and treating many hepatopancreaticobiliary (HPB) conditions. HPB disease is being diagnosed with increasing frequency in children but information about role of ERCP and EUS and their outcomes in this population remain limited. Therefore the aims of this study were to describe the paediatric ERCP and EUS experience from a large tertiary referral HPB centre, and to systematically compare outcomes with those of other published series...
February 9, 2018: BMC Pediatrics
https://www.readbyqxmd.com/read/29404819/significance-of-glucose-transporter-type-1-glut-1-expression-in-the-therapeutic-strategy-for-pancreatic-ductal-adenocarcinoma
#9
Hiroshi Kurahara, Kosei Maemura, Yuko Mataki, Masahiko Sakoda, Satoshi Iino, Yota Kawasaki, Takaaki Arigami, Shinichiro Mori, Yuko Kijima, Shinichi Ueno, Hiroyuki Shinchi, Shoji Natsugoe
BACKGROUND: This study aimed to examine the prognostic relevance of glucose transporter type 1 (GLUT-1), which is a key regulator of the glucose metabolism. In particular, the study aimed to examine the association between GLUT-1 expression and the therapeutic effect of chemoradiotherapy (CRT) in pancreatic ductal adenocarcinoma (PDAC). METHODS: Patients with PDAC were enrolled in the study. Patients with distant metastases and those who received only chemotherapy as treatment were excluded from the study...
February 5, 2018: Annals of Surgical Oncology
https://www.readbyqxmd.com/read/29394755/-radical-resection-of-huge-gastrointestinal-stromal-tumor-of-the-stomach-following-neoadjuvant-chemotherapy-with-lmatinib-acase-report
#10
Yoko Hiraki, Hiroaki Kato, Osamu Shiraishi, Yumiko Tanaka, Mitsuru Iwama, Atsushi Yasuda, Masayuki Shinkai, Yutaka Kimura, Motohiro Imano, Haruhiko Imamoto, Takushi Yasuda
The usefulness and safety of imatinibfor neoadjuvant chemotherapy for resectable gastrointestinal stromal tumor(GIST) has not been established. We reported a case of a huge GIST of the stomach that was safely resected following preoperative imatinibtherapy. A 69-year-old man was hospitalized with abdominal fullness which increased rapidly from a month ago. A CT scan showed a huge tumor containing solid and cystic component which was accompanied by an extra-wall nodule. The tumor was strongly suspected to be originated from the stomach and EUS-FNA revealed GIST...
November 2017: Gan to Kagaku Ryoho. Cancer & Chemotherapy
https://www.readbyqxmd.com/read/29387709/therapeutic-eus-biliary-drainage-the-interventional-radiologist-s-perspective
#11
Francesco De Cobelli, Paolo Marra, Pietro Diana, Giorgio Brembilla, Massimo Venturini
No abstract text is available yet for this article.
December 2017: Endoscopic Ultrasound
https://www.readbyqxmd.com/read/29382047/reviewing-the-utility-of-eus-fna-to-advance-precision-medicine-in-pancreatic-cancer
#12
REVIEW
William Berry, Joanne Lundy, Daniel Croagh, Brendan J Jenkins
Advanced pancreatic cancer (PC) is an aggressive malignancy with few effective therapeutic options. While the evolution of precision medicine in recent decades has changed the treatment landscape in many cancers, at present no targeted therapies are used in the routine management of PC. Only a minority of patients with PC present with surgically resectable disease, and in the remainder obtaining high quality biopsy material for both diagnosis and molecular testing can prove challenging. Endoscopic ultrasound-guided fine needle aspiration (EUS FNA) is a widely used diagnostic procedure in PC, and allows tumour sampling in patients with both early and late stage disease...
January 27, 2018: Cancers
https://www.readbyqxmd.com/read/29375740/mediastinal-node-staging-by-positron-emission-tomography-computed-tomography-and-selective-endoscopic-ultrasound-with-fine-needle-aspiration-for-patients-with-upper-gastrointestinal-cancer-results-from-a-regional-centre
#13
Chris Harrington, Lyn Smith, Jennifer Bisland, Elisabet López González, Neil Jamieson, Stuart Paterson, Adrian John Stanley
AIM: To investigate the impact of endoscopic ultrasound-guided fine-needle aspiration (EUS-FNA) and positron emission tomography-computed tomography (PET-CT) in the nodal staging of upper gastrointestinal (GI) cancer in a tertiary referral centre. METHODS: We performed a retrospective review of prospectively recorded data held on all patients with a diagnosis of upper GI cancer made between January 2009 and December 2015. Only those patients who had both a PET-CT and EUS with FNA sampling of a mediastinal node distant from the primary tumour were included...
January 16, 2018: World Journal of Gastrointestinal Endoscopy
https://www.readbyqxmd.com/read/29349694/endoscopic-ultrasound-guided-rendezvous-technique-for-failed-biliary-cannulation-in-benign-and-resectable-malignant-biliary-disorders
#14
Hideyuki Shiomi, Kentaro Yamao, Noriyuki Hoki, Takeshi Hisa, Takeshi Ogura, Kosuke Minaga, Atsuhiro Masuda, Kazuya Matsumoto, Hironari Kato, Hideki Kamada, Daisuke Goto, Hajime Imai, Mamoru Takenaka, Chishio Noguchi, Hidefumi Nishikiori, Yasutaka Chiba, Hiromu Kutsumi, Masayuki Kitano
BACKGROUND: Endoscopic ultrasound-guided rendezvous technique (EUS-RV) has emerged as an effective salvage method for unsuccessful biliary cannulation. However, its application for benign and resectable malignant biliary disorders has not been fully evaluated. AIMS: To assess the efficacy and safety of EUS-RV for benign and resectable malignant biliary disorders. METHODS: This was a multicenter prospective study from 12 Japanese referral centers...
March 2018: Digestive Diseases and Sciences
https://www.readbyqxmd.com/read/29332405/endoscopic-ultrasound-guided-choledochoduodenostomy-after-a-failed-or-impossible-ercp
#15
Ana María Mora Soler, Alberto Álvarez Delgado, María Concepción Piñero Pérez, Antonio Velasco-Guardado, Marcos Prieto Héctor, Antonio Rodríguez Pérez
INTRODUCTION: Endoscopic ultrasound-guided biliary drainage (EUS-BD) is an alternative to percutaneous trans-hepatic biliary drainage (PTBD) in cases of failed endoscopic retrograde cholangiopancreatography (ERCP). METHODS: This is a retrospective description of six cases of endoscopic ultrasound-guided biliary drainage via choledochoduodenostomy (EUCD), as well as the clinical characteristics, endoscopic procedure, complications and monitoring. RESULTS: All cases had malignant distal biliary obstruction...
January 15, 2018: Revista Española de Enfermedades Digestivas
https://www.readbyqxmd.com/read/29317267/spiral-enteroscopy-assisted-ercp-in-bariatric-length-roux-en-y-anatomy-a-large-single-center-series-and-review-of-the-literature-with-video
#16
Mohammad F Ali, Rani Modayil, Krishna C Gurram, Collin E M Brathwaite, David Friedel, Stavros N Stavropoulos
BACKGROUND: Deep enteroscopy-assisted ERCP (DEA-ERCP) in post-bariatric Roux-en-Y (RY) anatomy is challenging. Laparoscopy-assisted ERCP (LA-ERCP) and EUS-directed transgastric ERCP (EDGE) are technically easier and faster but are more invasive and morbid procedures. Therefore, we have used DEA-ERCP as our first-line approach, reserving EDGE and LA-ERCP for cases in which adjunctive techniques that cannot be performed through an enteroscope are required (eg, EUS-FNA, sleeve sphincter of Oddi manometry), or DEA-ERCP failures...
January 6, 2018: Gastrointestinal Endoscopy
https://www.readbyqxmd.com/read/29310413/usefulness-of-combined-percutaneous-endoscopic-rendezvous-techniques-after-failed-therapeutic-endoscopic-retrograde-cholangiography-in-the-era-of-endoscopic-ultrasound-guided-rendezvous
#17
Min Jae Yang, Jin Hong Kim, Jae Chul Hwang, Byung Moo Yoo, Soon Sun Kim, Sun Gyo Lim, Je Hwan Won
The rendezvous approach is a salvage technique after failure of endoscopic retrograde cholangiography (ERC). In certain circumstances, percutaneous-endoscopic rendezvous (PE-RV) is preferred, and endoscopic ultrasound-guided rendezvous (EUS-RV) is difficult to perform. We aimed to evaluate PE-RV outcomes, describe the PE-RV techniques, and identify potential indications for PE-RV over EUS-RV.Retrospective analysis was conducted of a prospectively designed ERC database between January 2005 and December 2016 at a tertiary referral center including cases where PE-RV was used as a salvage procedure after ERC failure...
December 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29282638/efficacy-and-safety-of-lumen-apposing-metal-stents-in-management-of-pancreatic-fluid-collections-are-they-better-than-plastic-stents-a-systematic-review-and-meta-analysis
#18
REVIEW
Tariq Hammad, Muhammad Ali Khan, Yaseen Alastal, Wade Lee, Ali Nawras, Mohammad Kashif Ismail, Michel Kahaleh
BACKGROUND AND AIMS: Endoscopic ultrasound (EUS)-guided transmural drainage has been increasingly utilized as a first-line therapeutic modality for drainage of pancreatic fluid collections (PFC). Recently, lumen-apposing metal stents (LAMS) have been utilized for management of PFCs. We conducted a systematic review and meta-analysis to evaluate the cumulative efficacy and safety of LAMS in the management of PFC (primary outcome). We also compared the efficacy and safety of LAMS with multiple plastic stents (MPS) in the management of PFC (secondary outcome)...
February 2018: Digestive Diseases and Sciences
https://www.readbyqxmd.com/read/29251269/ii-brazilian-consensus-statement-on-endoscopic-ultrasonography
#19
Fauze Maluf-Filho, Joel Fernandez de Oliveira, Ernesto Quaresma Mendonça, Augusto Carbonari, Bruno Antônio Maciente, Bruno Chaves Salomão, Bruno Frederico Medrado, Carlos Marcelo Dotti, César Vivian Lopes, Cláudia Utsch Braga, Daniel Alencar M Dutra, Felipe Retes, Frank Nakao, Giovana Biasia de Sousa, Gustavo Andrade de Paulo, Jose Celso Ardengh, Juliana Bonfim Dos Santos, Luciana Moura Sampaio, Luciano Okawa, Lucio Rossini, Manoel Carlos de Brito Cardoso, Marco Antonio Ribeiro Camunha, Marcos Clarêncio, Marcos Eduardo Lera Dos Santos, Matheus Franco, Nutianne Camargo Schneider, Ramiro Mascarenhas, Rodrigo Roda, Sérgio Matuguma, Simone Guaraldi, Viviane Figueiredo
BACKGROUND AND OBJECTIVES: At the time of its introduction in the early 80s, endoscopic ultrasonography (EUS) was indicated for diagnostic purposes. Recently, EUS has been employed to assist or to be the main platform of complex therapeutic interventions. METHODS: From a series of relevant new topics in the literature and based on the need to complement the I Brazilian consensus on EUS, twenty experienced endosonographers identified and reviewed the pertinent literature in databases...
November 2017: Endoscopic Ultrasound
https://www.readbyqxmd.com/read/29212476/the-role-of-endoscopic-ultrasound-in-children-with-pancreatobiliary-and-gastrointestinal-disorders-a-single-center-series-and-review-of-the-literature
#20
Alessandro Fugazza, Barbara Bizzarri, Federica Gaiani, Marco Manfredi, Alessia Ghiselli, Pellegrino Crafa, Maria Clotilde Carra, Nicola de'Angelis, Gian Luigi de'Angelis
BACKGROUND: The role of endoscopic ultrasound (EUS) in the management of pancreatobiliary and digestive diseases is well established in adults, but it remains limited in children. The aim of this study was to evaluate the feasibility, safety, and clinical impact of EUS use in children. METHODS: This is a retrospective analysis of a prospectively acquired database of consecutive pediatric (< 18 years) patients presenting an indication for EUS for pancreatobiliary and gastrointestinal disorders...
December 6, 2017: BMC Pediatrics
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