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THERAPEUTIC EUS

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https://www.readbyqxmd.com/read/29212476/the-role-of-endoscopic-ultrasound-in-children-with-pancreatobiliary-and-gastrointestinal-disorders-a-single-center-series-and-review-of-the-literature
#1
Alessandro Fugazza, Barbara Bizzarri, Federica Gaiani, Marco Manfredi, Alessia Ghiselli, Pellegrino Crafa, Maria Clotilde Carra, Nicola de'Angelis, Gian Luigi de'Angelis
BACKGROUND: The role of endoscopic ultrasound (EUS) in the management of pancreatobiliary and digestive diseases is well established in adults, but it remains limited in children. The aim of this study was to evaluate the feasibility, safety, and clinical impact of EUS use in children. METHODS: This is a retrospective analysis of a prospectively acquired database of consecutive pediatric (< 18 years) patients presenting an indication for EUS for pancreatobiliary and gastrointestinal disorders...
December 6, 2017: BMC Pediatrics
https://www.readbyqxmd.com/read/29122598/effects-of-eus-guided-intratumoral-injection-of-oligonucleotide-stnm01-on-tumor-growth-histology-and-overall-survival-in-patients-with-unresectable-pancreatic-cancer
#2
Makoto Nishimura, Miho Matsukawa, Yuko Fujii, Yoko Matsuda, Tomio Arai, Yasutoshi Ochiai, Takao Itoi, Naohisa Yahagi
BACKGROUND AND AIMS: Carbohydrate sulfotransferase 15 (CHST15) promotes tumor growth and invasion and is considered to be an emergent therapeutic target for pancreatic cancer. The aim of this study was to evaluate the safety and efficacy of EUS-guided fine-needle injection (EUS-FNI) of STNM01, the double-stranded RNA oligonucleotide that specifically represses CHST15, for use in patients with pancreatic cancer. METHODS: Six patients with unresectable pancreatic cancer, treated at Tokyo Metropolitan Geriatric Hospital, were used in this open-labeled, investigator-initiated trial...
November 6, 2017: Gastrointestinal Endoscopy
https://www.readbyqxmd.com/read/29075963/endoscopic-evaluation-and-management-of-gastric-stromal-tumors
#3
REVIEW
Kambiz Kadkhodayan, Ehsan Rafiq, Robert H Hawes
Purpose of Review Gastrointestinal stromal tumors (GISTs) are both relatively common. Management of these lesions has been challenging with emerging interest in the endoscopic approach for both diagnostic and therapeutic interventions. Recent Findings Although these can be visualized on CT scan, endoscopic ultrasound (EUS) represents the standard method of evaluation and characterization using fine needle aspiration cytology (FNA) when indicated. While EUS-FNA can yield diagnostic cells, full characterization requires a sufficient volume of viable cells to do molecular analysis for c-KIT and determine the mitotic index...
December 2017: Current Treatment Options in Gastroenterology
https://www.readbyqxmd.com/read/29055054/a-multicenter-prospective-evaluation-study-of-endoscopic-ultrasound-guided-hepaticogastrostomy-combined-with-antegrade-stenting-with-video
#4
Takeshi Ogura, Masayuki Kitano, Mamoru Takenaka, Atsushi Okuda, Kosuke Minaga, Kentaro Yamao, Yukitaka Yamashita, Keiichi Hatamaru, Chishio Noguchi, Yasuhiko Gotoh, Taira Kuroda, Tomoyuki Yokota, Hidefumi Nishikiori, Ryota Sagami, Kazuhide Higuchi, Yasutaka Chiba
OBJECTIVE: EUS-guided hepaticogastrostomy (EUS-HGS) is often indicated for advanced stage patients because it prevents the adverse events associated with EUS-HGS procedures, and provides long stent patency. EUS-guided antegrade stenting (AS) has been developed as an advanced technique. Thus, to prevent adverse events and achieve, long stent patency, EUS-AS combined with EUS-HGS (EUS-HGAS) has been reported. The aim of this study was to evaluate the technical feasibility and efficacy of EUS-HGAS in a multicenter, prospective study...
October 20, 2017: Digestive Endoscopy: Official Journal of the Japan Gastroenterological Endoscopy Society
https://www.readbyqxmd.com/read/28975061/endoscopic-dissolution-of-gastric-lipoma-with-argon-plasma-coagulation
#5
Abhilash Perisetti, Nayana George, Saikiran Raghavapuram, Abu Baker Sheikh, Mohit Girotra, Benjamin Tharian
A 47-year-old patient presented from outside the hospital for evaluation of iron deficiency anemia (IDA). The endoscopic workup suggested a gastric antral subepithelial lesion with an overlying arteriovenous malformation (AVM). Endoscopic ultrasound (EUS) revealed the lesion to be a lipoma. Given the patient's anemia and blood transfusion requirements, the AVM was treated with argon plasma coagulation (APC). During this treatment, desiccation of fat was noted with a significant decrease in the size of the subepithelial lesion (the gastric lipoma)...
July 31, 2017: Curēus
https://www.readbyqxmd.com/read/28941651/eus-and-related-technologies-for-the-diagnosis-and-treatment-of-pancreatic-disease-research-gaps-and-opportunities-summary-of-a-national-institute-of-diabetes-and-digestive-and-kidney-diseases-workshop
#6
REVIEW
Linda S Lee, Dana K Andersen, Reiko Ashida, William R Brugge, Mimi I Canto, Kenneth J Chang, Suresh T Chari, John DeWitt, Joo Ha Hwang, Mouen A Khashab, Kang Kim, Michael J Levy, Kevin McGrath, Walter G Park, Aatur Singhi, Tyler Stevens, Christopher C Thompson, Mark D Topazian, Michael B Wallace, Sachin Wani, Irving Waxman, Dhiraj Yadav, Vikesh K Singh
A workshop was sponsored by the National Institute of Diabetes and Digestive and Kidney Diseases to address the research gaps and opportunities in pancreatic EUS. The event occurred on July 26, 2017 in 4 sessions: (1) benign pancreatic diseases, (2) high-risk pancreatic diseases, (3) diagnostic and therapeutics, and (4) new technologies. The current state of knowledge was reviewed, with identification of numerous gaps in knowledge and research needs. Common themes included the need for large multicenter consortia of various pancreatic diseases to facilitate meaningful research of these entities; to standardize EUS features of different pancreatic disorders, the technique of sampling pancreatic lesions, and the performance of various therapeutic EUS procedures; and to identify high-risk disease early at the cellular level before macroscopic disease develops...
September 20, 2017: Gastrointestinal Endoscopy
https://www.readbyqxmd.com/read/28932347/role-of-endoscopic-ultrasound-in-liver-disease-where-do-we-stand-in-2017
#7
REVIEW
Hamzeh A Saraireh, Mohammad Bilal, Shailendra Singh
Endoscopic ultrasound (EUS) was first introduced into medical practice in 1980s as a diagnostic imaging modality for pancreatic pathology. EUS has the unique advantage of combining ultrasound and endoscopy to obtain detailed information of the gastrointestinal tract. Over the past decade, the use of EUS in liver diseases has been increasing. EUS, which was initially used as a diagnostic tool, is now having increasing therapeutic role as well. We provide a review of the application of EUS in the diagnostic and therapeutic aspects of liver disease...
August 28, 2017: World Journal of Hepatology
https://www.readbyqxmd.com/read/28926412/endoscopic-ultrasound-and-related-technologies-for-the-diagnosis-and-treatment-of-pancreatic-disease-research-gaps-and-opportunities-summary-of-a-national-institute-of-diabetes-and-digestive-and-kidney-diseases-workshop
#8
Linda S Lee, Dana K Andersen, Reiko Ashida, William R Brugge, Mimi I Canto, Kenneth J Chang, Suresh T Chari, John DeWitt, Joo Ha Hwang, Mouen A Khashab, Kang Kim, Michael J Levy, Kevin McGrath, Walter G Park, Aatur Singhi, Tyler Stevens, Christopher C Thompson, Mark D Topazian, Michael B Wallace, Sachin Wani, Irving Waxman, Dhiraj Yadav, Vikesh K Singh
A workshop was sponsored by the National Institute of Diabetes and Digestive and Kidney Diseases to address the research gaps and opportunities in pancreatic endoscopic ultrasound (EUS). The event occurred on July 26, 2017 in 4 sessions: (1) benign pancreatic diseases, (2) high-risk pancreatic diseases, (3) diagnostic and therapeutics, and (4) new technologies. The current state of knowledge was reviewed, with identification of numerous gaps in knowledge and research needs. Common themes included the need for large multicenter consortia of various pancreatic diseases to facilitate meaningful research of these entities; to standardize EUS features of different pancreatic disorders, the technique of sampling pancreatic lesions, and the performance of various therapeutic EUS procedures; and to identify high-risk disease early at the cellular level before macroscopic disease develops...
November 2017: Pancreas
https://www.readbyqxmd.com/read/28918811/future-directions-for-endoscopic-ultrasound-where-are-we-heading
#9
REVIEW
Sahin Coban, Omer Basar, William R Brugge
Endoscopic ultrasound (EUS) plays an important role as a diagnostic and therapeutic modality in gastroenterology. New developments have emerged, especially in the last decade, and are being introduced to endoscopists. The ability to readily visualize and access organs in the gastrointestinal tract has allowed endoscopists to perform new interventional procedures. EUS procedures have taken the place of conventional approaches for the treatment of various gastrointestinal diseases, including pancreatic cystic lesions...
October 2017: Gastrointestinal Endoscopy Clinics of North America
https://www.readbyqxmd.com/read/28918804/recent-advances-in-therapeutic-endosonography-for-cancer-treatment
#10
REVIEW
Saurabh Mukewar, Venkataraman Raman Muthusamy
Therapeutic endosonography (EUS) may play an important role in the management of cancers. EUS-guided fiducial placement has a high success rate and can aid in stereotactic radiotherapy. EUS-guided tumor ablation therapies can help in palliation of locally advanced tumors. EUS-guided antitumor injection seems to be feasible and safe in animals; initial human studies suffer from small sample size and lack of controls. Randomized, controlled trials have not shown benefit over conventional therapy. EUS celiac plexus neurolysis has gained popularity and is performed by interventional endosonographers...
October 2017: Gastrointestinal Endoscopy Clinics of North America
https://www.readbyqxmd.com/read/28918797/the-early-history-of-interventional-endoscopic-ultrasound
#11
REVIEW
Frank G Gress
Technological advances in the field of endoscopic ultrasound (EUS) have emerged, especially in the past decade, that have rapidly expanded the therapeutic potential of EUS, largely through the innovations of accessory technology that could not have happened without innovative changes to echoendoscopes. As interventional EUS continues to evolve, further expansion into previously uncharted areas will most certainly happen.
October 2017: Gastrointestinal Endoscopy Clinics of North America
https://www.readbyqxmd.com/read/28870046/-the-chinese-consensus-for-screening-diagnosis-and-management-of-barrett-s-esophagus-and-early-adenocarcinoma-2017-wanning
#12
(no author information available yet)
Patients with Barrett's esophagus (BE)/columnar lined esophagus (CLE) and adenocarcinoma are increasing, in whom 0.61% BE/CLE would develop to adenocarcinoma. The prognosis of esophageal cancer is related to the tumor stage at diagnosis. To standardize the screening, diagnosis and therapy of BE and adenocarcinoma in China, 31 digestive diseases and digestive endoscopy experts and digestive histologists drafted the consensus on the basis of clinical experience and references. The consensus defined BE as a complication of gastroesophageal reflux disease...
September 1, 2017: Zhonghua Nei Ke za Zhi [Chinese Journal of Internal Medicine]
https://www.readbyqxmd.com/read/28868481/the-role-of-endoscopic-ultrasound-in-the-diagnostic-assessment-of-subepithelial-lesions-of-the-upper-gastrointestinal-tract
#13
Francisca Dias de Castro, Joana Magalhães, Sara Monteiro, Sílvia Leite, José Cotter
INTRODUCTION: The identification of subepithelial lesions is a relatively frequent finding at endoscopy however their natural history is not well known. Our aim was to analyze the role of endoscopic ultrasound (EUS) in the diagnostic approach of subepithelial lesions of the upper gastrointestinal tract. METHODS: Retrospective study which included 324 patients undergoing upper radial EUS for evaluation of subepithelial lesions from 2008 to 2014. The EUS features, presumptive diagnosis and management decision were analyzed...
November 2016: GE Portuguese Journal of Gastroenterology
https://www.readbyqxmd.com/read/28839896/training-in-ercp-and-eus-in-the-uk-anno-2017
#14
REVIEW
Noor Lh Bekkali, Gavin J Johnson
In the last 20 years, endoscopic retrograde cholangiopancreatography (ERCP) has evolved from being a diagnostic procedure to being almost exclusively therapeutic. Similarly, endoscopic ultrasound (EUS) is developing into ever-increasing therapeutic roles. Operator technique is central to diagnostic accuracy in EUS, as is effective and safer therapy for both ERCP and therapeutic EUS. Hence, effective training and robust standards for certification and revalidation are required to ensure ERCP and EUS in the UK are as effective and as safe as possible...
April 2017: Frontline Gastroenterology
https://www.readbyqxmd.com/read/28839895/advancing-the-diagnostic-and-therapeutic-role-of-eus-in-pancreaticobiliary-disease-hopkins-lecture-2016
#15
Kofi Oppong
No abstract text is available yet for this article.
April 2017: Frontline Gastroenterology
https://www.readbyqxmd.com/read/28820145/endoscopic-ultrasound-guided-gastroenterostomy-are-we-ready-for-prime-time
#16
REVIEW
Mihai Rimbas, Alberto Larghi, Guido Costamagna
Interventional endoscopic ultrasonography (EUS) is currently becoming the less invasive therapeutic approach for the drainage of pancreatic fluid collections, of acute cholecystitis in patients unfit for surgery and for biliary drainage after failed endoscopic retrograde cholangiopancreatography. In addition, EUS-guided gastroenterostomy (EUS-GE) has recently emerged as a feasible procedure to treat patients with gastric outlet obstruction, as an alternative to surgery or to standard endoscopy when endoscopic stent placement is not possible...
July 2017: Endoscopic Ultrasound
https://www.readbyqxmd.com/read/28790162/the-future-diagnostic-and-imaging-advances-in-men1-therapeutic-approaches-and-management-strategies
#17
REVIEW
Jerena Manoharan, Max B Albers, Detlef K Bartsch
Prospective randomized data are lacking, but current clinical expert guidelines recommend annual screening examinations, including laboratory assessments and various imaging modalities (e.g. CT, MRI, scintigraphy and EUS) for patients with multiple endocrine neoplasia type 1 (MEN1). Routine screening is proposed to detect and localize neuroendocrine manifestations as early as possible. The goal is timely intervention to improve quality of life and to increase life expectancy by preventing the development of life-threatening hormonal syndromes and/or metastatic disease...
October 2017: Endocrine-related Cancer
https://www.readbyqxmd.com/read/28742731/endoscopic-ultrasound-guided-portal-venous-access-diagnostic-and-therapeutic-implications
#18
Rajat Garg, Tarun Rustagi
Endoscopic ultrasound (EUS) has evolved from a purely diagnostic to an interventional modality offering minimally invasive alternatives to surgical and radiologic interventions. This has led to a rapidly growing interest in EUS-guided vascular interventions. EUS-guided portal venous access is an emerging technique which opens a new arena for interventional vascular EUS. Portal vein can be accessed under EUS guidance with high precision and low risk of complications thus expanding its application for both benign and malignant conditions...
July 24, 2017: Journal of Clinical Gastroenterology
https://www.readbyqxmd.com/read/28719966/safety-and-complications-of-interventional-endoscopic-ultrasound
#19
Monica Saumoy, Michel Kahaleh
Endoscopic ultrasound (EUS) has become an essential tool for the diagnostic and therapeutic intervention of gastrointestinal diseases. Beyond the drainage of fluid collections, it enables decompression of inaccessible bile and pancreatic ducts, the gallbladder, and the creation of anastomosis within the gastrointestinal tract using fully lumen-apposing stents. This review explored the safety and efficacy of these novel procedures and discussed the training pathway that is necessary to perform them efficiently and safely...
July 19, 2017: Clinical Endoscopy
https://www.readbyqxmd.com/read/28663529/impact-of-introduction-of-endoscopic-ultrasound-on-volume-success-and-complexity-of-endoscopic-retrograde-cholangiopancreatography-in-a-tertiary-referral-center
#20
Harathi Yandrapu, Sherif Elhanafi, Farhanaz Chowdhury, Jiayang Liu, Eduardo J Onate, Alok Dwivedi, Mohamed O Othman
BACKGROUND AND OBJECTIVES: Endoscopic ultrasound (EUS) is commonly used to examine pancreaticobiliary disorders. We hypothesize that the introduction of EUS service may change the pattern and the complexity of endoscopic retrograde cholangiopancreatographies (ERCPs) performed. The aim of this study is to assess the impact of introducing EUS on the volume, success, and complexity of ERCP. MATERIALS AND METHODS: This is a single-center retrospective data review of ERCP procedures done "before" and "after" the introduction of EUS (before EUS and after EUS)...
July 2017: Endoscopic Ultrasound
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