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https://www.readbyqxmd.com/read/28943539/leptomeningeal-collaterals-strongly-correlate-with-reduced-cerebrovascular-reactivity-measured-by-acetazolamide-challenged-single-photon-emission-computed-tomography-using-a-stereotactic-extraction-estimation-analysis-in-patients-with-unilateral-internal-carotid
#1
Takenobu Kunieda, Kosuke Miyake, Hiroki Sakamoto, Yuko Iwasaki, Shin Iida, Satoshi Morise, Kengo Fujita, Masataka Nakamura, Satoshi Kaneko, Hirofumi Kusaka
Objective To assess the correlation between the angiographic appearance of cerebral collateral pathways or the degree of internal carotid artery stenosis (ICAS) and reduced cerebrovascular reactivity (CVR) estimated by single-photon emission computed tomography (SPECT) image analysis in patients with unilateral ICAS. Methods A retrospective analysis was performed in 42 patients with unilateral ICAS who underwent cerebral angiography and acetazolamide-challenged SPECT of the brain. Cerebral blood flow quantitation was performed using the quantitative SPECT/dual-table autoradiography method...
September 25, 2017: Internal Medicine
https://www.readbyqxmd.com/read/28913763/a-patient-specific-three-dimensional-hemodynamic-model-of-the-circle-of-willis
#2
Hamed Rezaie, Ali Ashrafizadeh, Afsaneh Mojra
Circle of Willis (CoW) is one of the most important cerebral arteries in the human body and various attempts have been made to study the hemodynamic of blood flow in this vital part of the brain. In the present study, blood flow in a patient specific CoW is numerically modeled to predict disease-prone regions of the CoW. Medical images and computer aided design software are used to construct a realistic three-dimensional model of the CoW for this particular case. The arteries are considered as elastic conduits and the interactions between arterial walls and the blood flow are taken into account...
September 14, 2017: Cardiovascular Engineering and Technology
https://www.readbyqxmd.com/read/28903104/basilar-artery-diameter-is-inversely-associated-with-fetal-type-circle-of%C3%A2-willis
#3
Oscar H Del Brutto, Robertino M Mera, Aldo F Costa, Victor J Del Brutto
BACKGROUND: The relationship between basilar artery (BA) diameter and Circle of Willis (CoW) configuration has been scarcely investigated. We aimed to assess this association in community-dwelling older adults. METHODS: MRAs of 346 individuals were reviewed. Using generalized linear models adjusted for demographics and cardiovascular risk factors, we assessed the relationship between BA diameter and fetal and non-fetal types CoW, as well as the impact of this relationship on BA ectasia prevalence...
2017: European Neurology
https://www.readbyqxmd.com/read/28893009/intracranial-aneurysms-involving-circle-of-willis-in-a-child-with-human-immunodeficiency-virus-associated-vasculitis-a-rare-case-report
#4
Amol Madanlal Lahoti, Abhijit Kishor Taori, Avinash Parashuram Dhok, Jitesh Subhash Rawat, Nihar Umakant Chandak
Intracranial Arterial Aneurysms (IAAs) are relatively rare in paediatric population and they account for at least 10%-15% of haemorrhagic strokes which occur during the first two decades of life. Here we present a unique and unusual case of Human Immunodeficiency Virus (HIV) infected child who presented with intracranial aneurysms with formation of collaterals and vasculopathy, demonstrating low viral count despite receiving adequate antiretroviral treatment. Intracranial vascular involvement, their complications and its incidence in these patients may become increasingly common as the management of human immunodeficiency virus infection continues to improve and afflicted patients survive for longer periods because of advancement in the antiretroviral treatment...
July 2017: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/28891402/you-do-what-a-qualitative-investigation-into-the-motivation-to-volunteer-with-circles-of-support-and-accountability
#5
Giulia Lowe, Gwenda Willis, Kerry Gibson
Most community members are not accepting of individuals convicted for sexual offenses living in their communities, let alone having regular contact with them. However, a select number of community members choose to give their time to assist these individuals reintegrate from prison into the community. Circles of Support and Accountability (CoSA) was developed as a way to address the issues that many individuals convicted of sex offenses face, that is, little to no prosocial support in the community. In-depth, semistructured interviews were conducted with 18 CoSA volunteers in New Zealand to gain a more thorough understanding of volunteers' motivation to be involved with CoSA...
September 1, 2017: Sexual Abuse: a Journal of Research and Treatment
https://www.readbyqxmd.com/read/28882859/flow-diversion-with-low-profile-braided-stents-for-the-treatment-of-very-small-or-uncoilable-intracranial-aneurysms-at-or-distal-to-the-circle-of-willis
#6
K Aydin, M Barburoglu, S Sencer, M Berdikhojayev, B Coskun, S Akpek
BACKGROUND AND PURPOSE: The endovascular treatment of aneurysms located at or distal to the circle of Willis and not amenable to coiling remains a challenge. We report our experience with flow-diversion treatment using low-profile braided stents as a stent monotherapy procedure for treating distally located very small or uncoilable aneurysms. MATERIALS AND METHODS: We retrospectively reviewed our data bases to identify patients with aneurysms located at or distal to the circle of Willis who were treated with stent monotherapy using low-profile braided stents...
September 7, 2017: AJNR. American Journal of Neuroradiology
https://www.readbyqxmd.com/read/28879893/a-novel-swine-model-of-subarachnoid-hemorrhage-induced-cerebral-vasospasm
#7
Zion Zibly, Lory Fein, Mayur Sharma, Yaron Assaf, Anton Wohl, Sagi Harnof
OBJECTIVE: One of the most serious complications following subarachnoid hemorrhage (SAH) is delayed cerebral ischemia (DCI) secondary to symptomatic vasospasm. An animal model mimicking post SAH vasospasm is essential for enabling the translation of newer technologies from the conceptual phase to animal studies, and eventually to clinical trials. Various animal models of DCI following SAH have been reported, with canine models being the most common. Due to the similarity of the swine cardiovascular system and its dimensions to the human's system, the main objective of this study was to establish a consistent and quantitatively representative model of SAH-induced vasospasm in swine...
September 2017: Neurology India
https://www.readbyqxmd.com/read/28860105/ascertaining-the-value-of-noninvasive-measures-obtained-using-color-duplex-ultrasound-and-central-aortic-pressure-monitoring-during-the-management-of-cerebral-arteriovenous-malformation-resection-protocol-for-a-prospective-case-control-pilot-study
#8
Kathryn J Busch, Hosen Kiat
BACKGROUND: Dramatic hemodynamic changes occur upon removal of an arteriovenous malformation of the brain (bAVM) with a number of potentially serious perioperative complications, such as intracranial hemorrhage and venous occlusive hypertensive syndrome. As these complications largely occur in the postoperative inpatient period, a rapid, repeatable noninvasive investigation to serially monitor relevant intracranial hemodynamics may be of benefit. Though, transcranial Doppler (TCD) and transcranial color duplex (TCCD) are techniques used and available to provide hemodynamic measurements postoperatively, the time course of hemodynamic sequences following bAVM resection remains uncertain...
August 31, 2017: JMIR Research Protocols
https://www.readbyqxmd.com/read/28856460/late-onset-pompe-disease-a-genetic-radiological-correlation-on-cerebral-vascular-anomalies
#9
A Pichiecchio, S Sacco, P De Filippi, E Caverzasi, S Ravaglia, S Bastianello, C Danesino
Pompe disease is an autosomal recessive disorder in which deficiency of the lysosomal enzyme acid alpha-glucosidase results in the accumulation of glycogen mostly in muscle tissues. Several reports suggest a higher incidence of intracranial vascular abnormalities (IVAs) in this condition, as well as brain microbleeds and cerebral vasculopathy. The aim of our study was to evaluate through neuroimaging studies the incidence of these anomalies in our cohort of late-onset Pompe disease (LOPD) patients asymptomatic for cerebrovascular disease, looking for correlations with clinical and genetic data...
August 30, 2017: Journal of Neurology
https://www.readbyqxmd.com/read/28845749/patterns-of-acute-ischemic-strokes-after-carotid-endarterectomy-and-therapeutic-implications
#10
Fabien Lareyre, Juliette Raffort, Caroline Weill, Claire Marsé, Laurent Suissa, Julien Chikande, Réda Hassen-Khodja, Elixène Jean-Baptiste
AIM: Acute ischemic strokes following surgical treatment of carotid stenosis lead to substantial disability and mortality, and vascular mechanisms underlying their development are not fully elucidated. The goal of this study was to analyze the topographic patterns of acute ischemic stroke following carotid endarterectomy (CEA) on diffusion-weighted and perfusion-weighted magnetic resonance imaging (MRI). MATERIAL AND METHODS: Data were retrospectively collected from consecutive patients who underwent CEA and developed postoperative acute ischemic stroke...
January 1, 2017: Vascular and Endovascular Surgery
https://www.readbyqxmd.com/read/28831614/non-invasive-blood-flow-features-estimation-in-cerebral-arteries-from-uncertain-medical-data
#11
R Lal, F Nicoud, E Le Bars, J Deverdun, F Molino, V Costalat, B Mohammadi
A methodology for non-invasive estimation of the pressure in internal carotid arteries is proposed. It uses data assimilation and Ensemble Kalman filters in order to identify unknown parameters in a mathematical description of the cerebral network. The approach uses patient specific blood flow rates extracted from Magnetic Resonance Angiography and Magnetic Resonance Imaging. This construction is necessary as the simulation of blood flows in complex arterial networks, such as the circle of Willis, is not straightforward because hemodynamic parameters are unknown as well as the boundary conditions necessary to close this complex system with many outlets...
August 22, 2017: Annals of Biomedical Engineering
https://www.readbyqxmd.com/read/28814167/cardio-cephalic-neural-crest-syndrome-a-novel-hypothesis-of-vascular-neurocristopathy
#12
M Komiyama
A novel hypothesis proposes that "cardio-cephalic neural crest (NC) syndrome," i.e. cephalic NC including cardiac NC, contributes to the concurrent occurrence of vascular diseases in the cardio- and cerebrovascular regions. NC is a transient structure present in early embryogenesis. Cephalic NC provides mesenchymal cells to the vascular media in these regions. Concurrent cardio- and cerebrovascular lesions have been reported in PHACE syndrome, ACTA2 mutation syndrome, and less frequently in the spontaneous occlusion of the circle of Willis (so-called moyamoya disease)...
January 1, 2017: Interventional Neuroradiology
https://www.readbyqxmd.com/read/28798217/multicenter-experience-with-fred-jr-flow-re-direction-endoluminal-device-for-intracranial-aneurysms-in-small-arteries
#13
M A Möhlenbruch, O Kizilkilic, M Killer-Oberpfalzer, F Baltacioglu, C Islak, M Bendszus, S Cekirge, I Saatci, N Kocer
BACKGROUND AND PURPOSE: Flow diverters are emerging as an endovascular treatment alternative for proximally located intracranial aneurysms. However, treatment of aneurysms at and beyond the circle of Willis is not well-established. We assessed the clinical safety and efficacy of the Flow Re-Direction Endoluminal Device Jr (FRED Jr) dedicated to small-vessel diameters between 2.0 and 3.0 mm. MATERIALS AND METHODS: This was a multicenter observational clinical study of 42 patients with 47 aneurysms treated by a flow-direction technique with the FRED Jr...
August 10, 2017: AJNR. American Journal of Neuroradiology
https://www.readbyqxmd.com/read/28790006/the-relationship-between-the-direction-of-putaminal-intracerebral-hemorrhage-and-anterior-cerebral-artery-predominance
#14
Jae-Ho Lee, Chul-Hoon Chang, Young-Jin Jung, Jong-Hoon Kim
INTRODUCTION: It is expected that anatomical variations in the circle of Willis have a direct effect on blood flow in the internal carotid artery. Rupture of the lenticulostriate artery of the middle cerebral artery 1st segment (M1) is the most common cause of putaminal intracerebral hemorrhage(ICH), and we hypothesized that this could be related to the anatomical variations of the circle of Willis and the predominance of the anterior cerebral artery 1st segment (A1). METHODS: We retrospectively reviewed the records of 544 patients who were treated for spontaneous ICH between 2013 and 2016 at Yeungnam University Hospital...
August 5, 2017: World Neurosurgery
https://www.readbyqxmd.com/read/28774679/ultra-high-field-tof-mra-a-method-to-visualize-small-cerebral-vessels-7t-tof-mra-sequence-parameters-on-different-mri-scanners-literature-review
#15
REVIEW
Cezary Grochowski, Grzegorz Staśkiewicz
INTRODUCTION: Time-of-flight (TOF) angiography is a technique allowing to visualize the blood flow in vessels. 7T ToF-MRA is able to visualize the whole Circle of Willis including small perforating branches without any known side effects as opposed to usually used DSA and CTA with high exposition to the radiation and high doses of contrast as far as CTA is concerned. AIM: The aim of this review is to describe ultra-high field ToF-MRA and present different protocol data depending on the scanner used in the study...
July 8, 2017: Neurologia i Neurochirurgia Polska
https://www.readbyqxmd.com/read/28746428/the-association-of-the-circle-of-willis-anomaly-and-risk-of-stroke-in-patients-with-carotid-artery-disease
#16
Eylem Özaydın Göksu, Pınar Koç, Elif Küçükseymen, Ali Ünal, Fatma Genç, Elif Sarıönder Gencer, Aylin Yaman
Results: In this retrospective study, we analyzed 175 patients who presented at our outpatient stroke clinic between January, 2013 and June, 2015 with either unilateral symptomatic or asymptomatic carotid artery disease, and who had had CT angiography imaging performed. Demographic properties, carotid artery stenosis and the anomaly of the circle of Willis was recorded. Conclusion: There was no statistically significant difference in patients with symptomatic and asymptomatic carotid artery disease in terms of the anomaly of the circle of Willis...
July 2017: Arquivos de Neuro-psiquiatria
https://www.readbyqxmd.com/read/28745664/-predictors-of-cerebral-complications-during-carotid-endarterectomy
#17
O V Kamenskaya, I Yu Loginova, V V Lomivorotov
AIM: To evaluate the prognostic value of parameters of cerebral oxygenation in estimation of the risk of ischemic stroke (IS) in perioperative and early postoperative phase of carotid endarterectomy (CEE). MATERIAL AND METHODS: Four hundred and sixty-six patients with hemodynamically significant atherosclerotic lesion of arteries of the brachiocephalic system, who underwent CEE with bilateral monitoring of cerebral oxygenation (rSO2), were enrolled. The end-point of the study was cerebral complications in perioperative and early postoperative phase...
2017: Zhurnal Nevrologii i Psikhiatrii Imeni S.S. Korsakova
https://www.readbyqxmd.com/read/28736349/completion-of-the-circle-of-willis-varies-by-gender-age-and-indication-for-computed-tomography-angiography
#18
Orel A Zaninovich, Wyatt L Ramey, Christina M Walter, Travis M Dumont
OBJECTIVE: The circle of Willis (CoW) is the foremost anastomosis and blood distribution center of the brain. Its effectiveness depends on its completion and the size and patency of its vessels. Gender-related and age-related anatomic variations in the CoW may play an important role in the pathogenesis of cerebrovascular diseases. In this study, we analyzed computed tomography angiograms (CTAs) to assess for differences in CoW completion related to gender, age, and indication for CTA...
October 2017: World Neurosurgery
https://www.readbyqxmd.com/read/28718269/non-atherosclerotic-obliteration-of-bilateral-supraclinoid-internal-carotid-arteries-a-classic-case-of-moyamoya-disease
#19
Saad Ullah, Anas Ahmed Siddiqui, Waseem Zaid Alkilani, Noman Ahmed Jang Khan, Hafiz Umair Siddiqui
Moyamoya disease is an idiopathic progressive vasculopathy of distal internal carotid artery and circle of Willis which leads to the development of characteristic smoky appearance of the vascular collateral network on angiography. With the highest reported incidence among Japanese population, it has been under recognized as a cause of cerebrovascular accidents in Western countries. Here we report a case of a young 20-year-old Caucasian woman who presented to the emergency department with expressive aphasia, right arm weakness and numbness for three days...
April 2017: Journal of Ayub Medical College, Abbottabad: JAMC
https://www.readbyqxmd.com/read/28701579/detecting-intracranial-vessel-wall-lesions-with-7t-magnetic-resonance-imaging-patients-with-posterior-circulation-ischemia-versus-healthy-controls
#20
Anita A Harteveld, Anja G van der Kolk, H Bart van der Worp, Nikki Dieleman, Jaco J M Zwanenburg, Peter R Luijten, Jeroen Hendrikse
BACKGROUND AND PURPOSE: Vessel wall magnetic resonance imaging sequences have been developed to directly visualize the intracranial vessel wall, enabling detection of vessel wall changes, including those that have not yet caused luminal narrowing. In this study, vessel wall lesion burden was assessed in patients with recent posterior circulation ischemia using 7T-magnetic resonance imaging and compared with matched healthy controls. METHODS: Fifty subjects (25 patients and 25 matched healthy controls) underwent 7T-magnetic resonance imaging with an intracranial vessel wall sequence before and after contrast administration...
September 2017: Stroke; a Journal of Cerebral Circulation
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