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Columbia University Medical Center

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https://www.readbyqxmd.com/read/29913278/low-rates-of-screening-for-celiac-disease-among-family-members
#1
Adam S Faye, Fernanda Polubriaginof, Peter H R Green, David K Vawdrey, Nicholas Tatonetti, Benjamin Lebwohl
BACKGROUND & AIMS: Given the increased morbidity and potential mortality of celiac disease, guidelines recommend screening high-risk individuals, including first-degree relatives of patients. We assessed how commonly celiac disease testing occurs in these individuals and identified factors that influence testing. METHODS: Relatives of 2081 patients with biopsy-diagnosed celiac disease and followed at Columbia University Medical Center were identified using relationship inference from the electronic health record-a validated method that uses emergency contact information to identify familial relationships...
June 15, 2018: Clinical Gastroenterology and Hepatology
https://www.readbyqxmd.com/read/29858417/putative-mechanisms-underlying-myocardial-infarction-onset-and-emotions-pume-a-randomised-controlled-study-protocol
#2
Ipek Ensari, Matthew M Burg, Keith M Diaz, Jie Fu, Andrea T Duran, Jerry M Suls, Jennifer A Sumner, Rachel Monane, Jacob E Julian, Shuqing Zhao, William F Chaplin, Daichi Shimbo
INTRODUCTION: The experience of negative emotions (eg, anger, anxiety and sadness) is associated with an increased short-term risk of incident cardiovascular disease (CVD) events, independent of traditional CVD risk factors. Impairment in endothelial function is one possible biological mechanism which may explain the association between negative emotions and incident CVD events. This laboratory-based, single-blind, randomised controlled experimental study aims to investigate the impact of induced negative emotions including anger, anxiety and sadness on endothelial function...
May 31, 2018: BMJ Open
https://www.readbyqxmd.com/read/29787740/conservative-management-following-clinical-complete-response-to-neoadjuvant-chemotherapy-for-muscle-invasive-bladder-cancer-contemporary-outcomes-of-a-multi-institutional-cohort-study
#3
Patrick Mazza, George W Moran, Gen Li, Dennis J Robins, Justin T Matulay, Harry W Herr, Guarionex J Decastro, James M McKiernan, Christopher B Anderson
PURPOSE: We report the outcomes of patients with muscle-invasive bladder cancer from two institutions who experienced a clinical complete response to neoadjuvant platinum-based chemotherapy and opted for active surveillance. It is unknown if conservative management can be safely implemented in these patients. MATERIALS AND METHODS: We performed a retrospective review of patients at Columbia University Medical Center and Memorial Sloan Kettering Cancer Center with muscle-invasive bladder cancer who elected surveillance following a clinical complete response to transurethral resection of bladder tumors and neoadjuvant chemotherapy from 2001-2017...
May 19, 2018: Journal of Urology
https://www.readbyqxmd.com/read/29738748/femur-sparing-pattern-of-abnormal-fetal-growth-in-pregnant-women-from-new-york-city-after-maternal-zika-virus-infection
#4
Christie L Walker, Audrey A Merriam, Eric O Ohuma, Manjiri K Dighe, Michael Gale, Lakshmi Rajagopal, Aris T Papageorghiou, Cynthia Gyamfi-Bannerman, Kristina M Adams Waldorf
BACKGROUND: Zika virus (ZIKV) is a mosquito-transmitted flavivirus, which can induce fetal brain injury and growth restriction following maternal infection during pregnancy. Prenatal diagnosis of ZIKV-associated fetal injury in the absence of microcephaly is challenging due to an incomplete understanding of how maternal ZIKV infection affects fetal growth and the use of different sonographic reference standards around the world. We hypothesized that skeletal growth is unaffected by ZIKV infection and that the femur length can represent an internal standard to detect growth deceleration of the fetal head and/or abdomen by ultrasound...
May 5, 2018: American Journal of Obstetrics and Gynecology
https://www.readbyqxmd.com/read/29485948/prospective-service-use-and-health-care-costs-of-medicaid-beneficiaries-with-treatment-resistant-depression
#5
Mark Olfson, Tony B Amos, Carmela Benson, Jacquelyn McRae, Steven C Marcus
BACKGROUND: Although the clinical and health economic characteristics of commercially insured adults with treatment-resistant depression (TRD) have been well characterized, little is known about TRD in the Medicaid population. OBJECTIVE: To describe clinical and health economic characteristics of adult Medicaid beneficiaries with TRD. METHODS: Retrospective longitudinal cohort analyses were performed with Truven Health MarketScan Medicaid Database (2008-2014), focusing on adults with major depressive disorder (MDD) following an index antidepressant prescription...
March 2018: Journal of Managed Care & Specialty Pharmacy
https://www.readbyqxmd.com/read/29407205/women-have-worse-cognitive-functional-and-psychiatric-outcomes-at-hospital-discharge-after-cardiac-arrest
#6
Sachin Agarwal, Alex Presciutti, Jayati Verma, Marykay A Pavol, Deepti Anbarasan, Daniel Brodie, Leroy E Rabbani, David J Roh, Soojin Park, Jan Claassen, Yaakov Stern
AIM: To examine gender differences among cardiac arrest (CA) survivors' cognitive, functional, and psychiatric outcomes at discharge. METHODS: This is a prospective, observational cohort of 187 CA patients admitted to Columbia University Medical Center, considered for Targeted Temperature Management (TTM), and survived to hospital discharge between September 2015 and July 2017. Patients with sufficient mental status at hospital discharge to engage in the Repeatable Battery for Neuropsychological Status (RBANS), Modified Lawton Physical Self-Maintenance Scale (M-PSMS), Cerebral Performance Category Scale (CPC), Center for Epidemiological Studies Depression Scale (CES-D), and Post-Traumatic Stress Disorder Checklist - Civilian Version (PCL-C) were included...
April 2018: Resuscitation
https://www.readbyqxmd.com/read/29402604/limited-usefulness-of-endoscopic-evaluation-in-patients-with-continuous-flow-left-ventricular-assist-devices-and-gastrointestinal-bleeding
#7
Jordan E Axelrad, Alberto Pinsino, Pauline N Trinh, Anusorn Thanataveerat, Christian Brooks, Ryan T Demmer, Lisa Effner, Grant Parkis, Barbara Cagliostro, Jiho Han, A Reshad Garan, Veli Topkara, Koji Takeda, Hiroo Takayama, Yoshifumi Naka, Ivonne Ramirez, Reuben Garcia-Carrasquillo, Paolo C Colombo, Tamas Gonda, Melana Yuzefpolskaya
BACKGROUND: Gastrointestinal bleeding (GIB) is a frequent cause of re-admission in patients with continuous-flow left ventricular assist devices (CF-LVADs) and is associated with multiple endoscopic procedures and high resource utilization. Our aim was to determine the diagnostic and therapeutic yield of endoscopy and to develop a more cost-effective approach for the management of GIB in CF-LVAD recipients. METHODS: We retrospectively reviewed 428 patients implanted with a CF-LVAD between 2009 and 2016 at the Columbia University Medical Center and identified those hospitalized for GIB...
December 20, 2017: Journal of Heart and Lung Transplantation
https://www.readbyqxmd.com/read/29382701/factors-associated-with-false-positive-results-on-screening-mammography-in-a-population-of-predominantly-hispanic-women
#8
Julia E McGuinness, William Ueng, Meghna S Trivedi, Hae Seung Yi, Raven David, Alejandro Vanegas, Jennifer Vargas, Rossy Sandoval, Rita Kukafka, Katherine D Crew
Background: Potential harms of screening mammography include false positive results, such as recall breast imaging or biopsies. Methods: We recruited women undergoing screening mammography at Columbia University Medical Center in New York, New York. They completed a questionnaire on breast cancer risk factors and permitted access to their medical records. Breast cancer risk status was determined using the Gail model and a family history screener. High risk was defined as a 5-year invasive breast cancer risk of ≥1...
April 2018: Cancer Epidemiology, Biomarkers & Prevention
https://www.readbyqxmd.com/read/29379824/palliative-care-opportunities-for-nursing
#9
EDITORIAL
Ayda Gan Nambayan
Ayda G. Nambayan, PhD, RN is the Training Consultant for The Ruth Foundation for Palliative and Hospice Care. Prior to this, she held various positions as a Consultant for Advanced Education and Training at Makati Medical Center, Philippines; a curriculum and distance learning developer for www.Cure4Kids.org, the educational website of the International Outreach Program of St. Jude Children's Research Hospital in Memphis, TN. In 2002, she retired from a faculty position from the University of Alabama at Birmingham, where she taught Adult Health Nursing for 25 years...
January 2018: Asia-Pacific Journal of Oncology Nursing
https://www.readbyqxmd.com/read/29315154/characteristics-and-comorbidities-of-inpatients-without-celiac-disease-on-a-gluten-free-diet
#10
John W Blackett, Meghana Shamsunder, Norelle R Reilly, Peter H R Green, Benjamin Lebwohl
OBJECTIVES: Despite the increasing popularity of gluten-free diet (GFD), the demographic characteristics and medical features of patients without celiac disease on this diet have not been extensively investigated.We aimed to characterize the medical conditions and demographic backgrounds of hospitalized patients without celiac disease who adhere to a GFD, to further understand their reasons for gluten avoidance. MATERIALS AND METHODS: We performed an observational cohort study on all inpatients at Columbia University Medical Center on a GFD in 2011-2016, excluding those with celiac disease, compared with age-matched and sex-matched inpatients on a regular diet...
April 2018: European Journal of Gastroenterology & Hepatology
https://www.readbyqxmd.com/read/29282433/understanding-breast-cancer-knowledge-and-barriers-to-treatment-adherence-a-qualitative-study-among-breast-cancer-survivors
#11
Rachel A Freedman, Anna C Revette, Dawn L Hershman, Kathryn Silva, Nora J Sporn, Joshua J Gagne, Elena M Kouri, Nancy L Keating
Disparities in breast cancer treatment receipt are common and multifactorial. Data are limited on how knowledge about one's breast cancer and understanding treatment rationales may impact treatment completion. In this qualitative analysis, we explored barriers to care with a focus on knowledge. We conducted 18 in-depth interviews with women from diverse socioeconomic backgrounds who were treated at Dana-Farber Cancer Institute ( n  = 12; Boston, MA) and Columbia University Medical Center ( n  = 6; New York, NY) and had undergone neo/adjuvant breast cancer treatment within the prior 3 years...
2017: BioResearch Open Access
https://www.readbyqxmd.com/read/29261540/looking-back-to-move-forward-first-year-medical-students-meta-reflections-on-their-narrative-portfolio-writings
#12
Hetty Cunningham, Delphine Taylor, Urmi A Desai, Samuel C Quiah, Benjamin Kaplan, Lorraine Fei, Marina Catallozzi, Boyd Richards, Dorene F Balmer, Rita Charon
The day-to-day rigors of medical education often preclude learners from gaining a longitudinal perspective on who they are becoming. Furthermore, the current focus on competencies, coupled with concerning rates of trainee burnout and a decline in empathy, have fueled the search for pedagogic tools to foster students' reflective capacity. In response, many scholars have looked to the tradition of narrative medicine to foster "reflective spaces" wherein holistic professional identity construction can be supported...
December 19, 2017: Academic Medicine: Journal of the Association of American Medical Colleges
https://www.readbyqxmd.com/read/29230636/predictors-of-improvement-in-bone-mineral-density-after-celiac-disease-diagnosis
#13
Haley M Zylberberg, Benjamin Lebwohl, Arindam RoyChoudhury, Marcella D Walker, Peter H R Green
PURPOSE: Low bone density is frequently found in patients newly diagnosed with celiac disease (CD), and improvement is variable. This study was performed to assess changes in bone mineral density (BMD) by dual x-ray absorptiometry (DXA) at the lumbar spine, hip, and distal one-third radius as well as clinical predictors of BMD changes after the diagnosis and treatment of CD. METHODS: Adult CD patients who had serial DXA at the Celiac Disease Center at Columbia University Medical Center were included (N = 103)...
February 2018: Endocrine
https://www.readbyqxmd.com/read/29214319/electrocardiographic-findings-in-national-basketball-association-athletes
#14
Marc P Waase, R Kannan Mutharasan, William Whang, Marco R DiTullio, John P DiFiori, Lisa Callahan, Jimmie Mancell, Dermot Phelan, Allan Schwartz, Shunichi Homma, David J Engel
Importance: While it is known that long-term intensive athletic training is associated with cardiac structural changes that can be reflected on surface electrocardiograms (ECGs), there is a paucity of sport-specific ECG data. This study seeks to clarify the applicability of existing athlete ECG interpretation criteria to elite basketball players, an athlete group shown to develop significant athletic cardiac remodeling. Objective: To generate normative ECG data for National Basketball Association (NBA) athletes and to assess the accuracy of athlete ECG interpretation criteria in this population...
January 1, 2018: JAMA Cardiology
https://www.readbyqxmd.com/read/29206598/is-there-unmeasured-indication-bias-in-radiation-related-cancer-risk-estimates-from-studies-of-computed-tomography
#15
Johanna M Meulepas, Michael Hauptmann, Jay H Lubin, Igor Shuryak, David J Brenner
Recently reported studies have associated radiation exposure from computed tomography (CT) scanning with small excess cancer risks. However, since existing medical records were used in these studies, they could not control for reasons for the CT scans and therefore, the results may have been confounded by indication. Here we conducted a study to estimate potential indication bias that could affect hazard ratios for colorectal, lung and female breast cancers by reasons for a CT scan. This involved a retrospective cohort study of electronic records from all patients aged 18-89 years without previous cancer diagnoses, who received at least one CT scan at Columbia University Medical Center in the period of 1994-2014...
February 2018: Radiation Research
https://www.readbyqxmd.com/read/29160596/chronic-pain-and-opioid-abuse-factors-associated-with-health-related-quality-of-life
#16
Jermaine D Jones, Jonathan S Vogelman, Rachel Luba, Mudassir Mumtaz, Sandra D Comer
BACKGROUND AND OBJECTIVES: While research on the separate relationships between health-related quality of life (HRQOL) and chronic pain, and HRQOL and opioid abuse has been sparse, even less work has investigated the factors associated with HRQOL in individuals who have both chronic pain and meet criteria for opioid use disorder. The data presented in this analysis should allow a better understanding the factors important to quality of life among this dual-diagnosed population. METHODS: Individuals with dual diagnoses of chronic pain and opioid use disorder were recruited for clinical research studies at Columbia University Medical Center...
December 2017: American Journal on Addictions
https://www.readbyqxmd.com/read/29075777/quantitative-autofluorescence-intensities-in-acute-zonal-occult-outer-retinopathy-vs-healthy-eyes
#17
Katherine A Boudreault, Kaspar Schuerch, Jin Zhao, Winston Lee, Thiago Cabral, Lawrence A Yannuzzi, Stephen H Tsang, Janet R Sparrow
Importance: Acute zonal occult outer retinopathy (AZOOR) remains a challenging diagnosis. Early recognition of the disease depends on advances in imaging modalities that can improve phenotyping and contribute to the understanding of the underlying pathogenesis. Objectives: To expand the range of approaches available to assist in the identification of AZOOR by multimodal imaging and to analyze the fundus lesions by quantifying short-wavelength fundus autofluorescence (quantitative fundus autofluorescence [qAF]) and spectral-domain optical coherence tomography...
December 1, 2017: JAMA Ophthalmology
https://www.readbyqxmd.com/read/28974993/e-mail-is-an-effective-tool-for-rapid-feedback-in-acute-stroke
#18
Sara K Rostanski, Joshua I Stillman, Lauren R Schaff, Crismely A Perdomo, Ava L Liberman, Eliza C Miller, Randolph S Marshall, Joshua Z Willey, Olajide Williams
OBJECTIVE: To determine whether e-mail is a useful mechanism to provide prompt, case-specific data feedback and improve door-to-needle (DTN) time for acute ischemic stroke treated with intravenous tissue plasminogen activator (IV-tPA) in the emergency department (ED) at a high-volume academic stroke center. METHODS: We instituted a quality improvement project at Columbia University Medical Center where clinical details are shared via e-mail with the entire treatment team after every case of IV-tPA administration in the ED...
October 2017: Neurohospitalist
https://www.readbyqxmd.com/read/28807486/gender-social-networks-and-stroke-preparedness-in-the-stroke-warning-information-and-faster-treatment-study
#19
Tracy E Madsen, Eric T Roberts, Heather Kuczynski, Emily Goldmann, Nina S Parikh, Bernadette Boden-Albala
BACKGROUND AND PURPOSE: The study aimed to investigate the effect of gender on the association between social networks and stroke preparedness as measured by emergency department (ED) arrival within 3 hours of symptom onset. METHODS: As part of the Stroke Warning Information and Faster Treatment study, baseline data on demographics, social networks, and time to ED arrival were collected from 1193 prospectively enrolled stroke/transient ischemic attack (TIA) patients at Columbia University Medical Center...
August 11, 2017: Journal of Stroke and Cerebrovascular Diseases: the Official Journal of National Stroke Association
https://www.readbyqxmd.com/read/28776047/an-interoperable-similarity-based-cohort-identification-method-using-the-omop-common-data-model-version-5-0
#20
Shreya Chakrabarti, Anando Sen, Vojtech Huser, Gregory W Hruby, Alexander Rusanov, David J Albers, Chunhua Weng
Cohort identification for clinical studies tends to be laborious, time-consuming, and expensive. Developing automated or semi-automated methods for cohort identification is one of the "holy grails" in the field of biomedical informatics. We propose a high-throughput similarity-based cohort identification algorithm by applying numerical abstractions on Electronic Health Records (EHR) data. We implement this algorithm using the Observational Medical Outcomes Partnership (OMOP) Common Data Model (CDM), which enables sites using this standardized EHR data representation to avail this algorithm with minimum effort for local implementation...
June 2017: Journal of Healthcare Informatics Research
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