Betina Idnay, Yilu Fang, Alex Butler, Joyce Moran, Ziran Li, Junghwan Lee, Casey Ta, Cong Liu, Chi Yuan, Huanyao Chen, Edward Stanley, George Hripcsak, Elaine Larson, Karen Marder, Wendy Chung, Brenda Ruotolo, Chunhua Weng
BACKGROUND: Randomized clinical trials (RCT) are the foundation for medical advances, but participant recruitment remains a persistent barrier to their success. This retrospective data analysis aims to (1) identify clinical trial features associated with successful participant recruitment measured by accrual percentage and (2) compare the characteristics of the RCTs by assessing the most and least successful recruitment, which are indicated by varying thresholds of accrual percentage such as ≥ 90% vs ≤ 10%, ≥ 80% vs ≤ 20%, and ≥ 70% vs ≤ 30%...
2023: Journal of Clinical and Translational Science