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https://www.readbyqxmd.com/read/28333301/preconception-maternal-lipoprotein-levels-in-relation-to-fecundability
#1
Sarah J Pugh, Enrique F Schisterman, Richard W Browne, Anne M Lynch, Sunni L Mumford, Neil J Perkins, Robert Silver, Lindsey Sjaarda, Joseph B Stanford, Jean Wactawski-Wende, Brian Wilcox, Katherine L Grantz
STUDY QUESTION: Are maternal preconception lipid levels associated with fecundability? SUMMARY ANSWER: Fecundability was reduced for all abnormal female lipid levels including total cholesterol, low-density lipoprotein cholesterol (LDL-C), high-density lipoprotein cholesterol (HDL-C) and total triglyceride levels. WHAT IS KNOWN ALREADY: Subfecundity affects 7-15% of the population and lipid disorders are hypothesized to play a role since cholesterol acts as a substrate for the synthesis of steroid hormones...
March 15, 2017: Human Reproduction
https://www.readbyqxmd.com/read/28329157/low-normalized-grip-strength-is-a-biomarker-for-cardiometabolic-disease-and-physical-disabilities-among-u-s-and-chinese-adults
#2
Mark D Peterson, Kate Duchowny, Qinqin Meng, Yafeng Wang, Xinxin Chen, Yaohui Zhao
Background: Evidence highlights the importance of muscular strength as a protective factor for health and function across aging populations. The purpose of this study was to examine the extent to which low normalized grip strength (NGS) serves as a biomarker for both cardiometabolic disease and physical disability in U.S. and Chinese adults. Methods: Middle aged and older adults from the U.S. National Health and Nutrition Examination Survey 2011-2012 and 2013-2014 combined surveys (n = 4,544), and the 2011 wave of the China Health and Retirement Longitudinal Study (n = 6,030) were included...
March 10, 2017: Journals of Gerontology. Series A, Biological Sciences and Medical Sciences
https://www.readbyqxmd.com/read/28327832/-frequency-of-metabolic-syndrome-in-residents-of-an-andean-region-in-peru
#3
Juana Aurelia Ninatanta-Ortiz, Luz Amparo Núñez-Zambrano, Segunda Aydeé García-Flores, Franco Romaní Romaní
Objectives.: To calculate the frequency of metabolic syndrome (MetS) and its associated characteristics in selected populations residing in the urban areas of two districts in the Cajamarca region. Materials and methods.: Cross-sectional study performed in 2014, obtaining randomized samples from three target study populations: high school students, university students, and schoolchildren mothers. In adults, MetS was defined by means of Third Adult Treatment Panel (ATP III) criteria, and in teenagers, the modified Cook criteria were used...
October 2016: Revista Peruana de Medicina Experimental y Salud Pública
https://www.readbyqxmd.com/read/28323999/metabolically-healthy-obesity-and-ischemic-heart-disease-a-10-year-follow-up-of-the-inter99-study
#4
Louise Hansen, Marie K Netterstrøm, Nanna B Johansen, Pernille F Rønn, Dorte Vistisen, Lise Ln Husemoen, Marit E Jørgensen, Naja H Rod, Kristine Færch
Context: Recent studies have suggested that a subgroup of obese individuals is not at increased risk of obesity-related complications. This subgroup has been referred to as metabolically healthy obese. Objective: To investigate whether obesity is a risk factor for development of ischemic heart disease (IHD) irrespective of metabolic health. Design: 6,238 men and women from the Danish prospective Inter99 study were followed during 10.6 (SD 1...
March 7, 2017: Journal of Clinical Endocrinology and Metabolism
https://www.readbyqxmd.com/read/28317295/two-year-follow-up-of-patients-with-septic-shock-presenting-with-low-hdl-the-effect-upon-acute-kidney-injury-death-and-estimated-glomerular-filtration-rate
#5
K Roveran Genga, C Lo, M Cirstea, G Zhou, K R Walley, J A Russell, A Levin, J H Boyd
BACKGROUND: Sepsis is associated with decreased levels of high-density lipoprotein (HDL) cholesterol. HDL has anti-inflammatory properties, and the use of Apo A-I mimetic peptides is associated with renal function improvement in animal models of sepsis. However, it is not known whether decreased HDL level results in impaired renal function in human sepsis. We investigated whether low levels of HDL conferred an increased risk of sepsis-associated acute kidney injury (AKI) or long-term decreased estimated glomerular filtration rate (eGFR) after sepsis...
March 19, 2017: Journal of Internal Medicine
https://www.readbyqxmd.com/read/28288621/relationship-between-plasma-homocysteine-level-and-lipid-profiles-in-a-community-based-chinese-population
#6
Mohetaboer Momin, Jia Jia, Fangfang Fan, Jianping Li, Jingtao Dou, Dafang Chen, Yong Huo, Yan Zhang
BACKGROUND: Previous studies established a possible link among hyperhomocysteinemia (HHcy), dyslipidemia, and atherosclerosis. However, there was limited epidemic data concerning the relation between HHcy and lipid profiles, especially in community-based Chinese populations. This study aim to investigate the association of plasma homocysteine (Hcy) level with lipid profiles in a Chinese community-based population without lipid-lowering treatment. METHOD: A total of 4660 Chinese subjects from a cohort of the Shijingshan district in Beijing were included in the analysis...
March 14, 2017: Lipids in Health and Disease
https://www.readbyqxmd.com/read/28287268/nmr-based-lipid-profiling-of-high-density-lipoprotein-particles-in-healthy-subjects-with-low-normal-and-elevated-hdl-cholesterol
#7
Christina E Kostara, Vasilis Tsimihodimos, Moses S Elisaf, Eleni T Bairaktari
Recent studies suggest that the cholesterol content of HDL (High Density Lipoproteins) lipoproteins may provide limited information on their antiatherogenic properties and that the composition and particles' structure provide more information on their functionality. We used NMR-based (Nuclear Magnetic Resonance-based) lipidomics to study the relationships of serum HDL-C (HDL-Cholesterol) levels with the lipid composition of HDL particles in three groups of subjects selected on the basis of their HDL-C levels...
March 13, 2017: Journal of Proteome Research
https://www.readbyqxmd.com/read/28285650/plasma-hdl-cholesterol-and-triglycerides-but-not-ldl-cholesterol-are-associated-with-insulin-secretion-in-non-diabetic-subjects
#8
Andrea Natali, Simona Baldi, Fabrice Bonnet, John Petrie, Silvia Trifirò, Domenico Tricò, Andrea Mari
OBJECTIVE: Experimental data support the notion that lipoproteins might directly affect beta cell function, however clinical data are sparse and inconsistent. We aimed at verifying whether, independently of major confounders, serum lipids are associated with alterations in insulin secretion or clearance non-diabetic subjects. METHODS: Cross sectional and observational prospective (3.5yrs), multicentre study in which 1016 non-diabetic volunteers aged 30-60yrs. and with a wide range of BMI (20...
April 2017: Metabolism: Clinical and Experimental
https://www.readbyqxmd.com/read/28282020/prevalence-of-low-high-density-lipoprotein-cholesterol-among-adults-by-physical-activity-united-states-2011-2014
#9
Marissa L Zwald, Lara J Akinbami, Tala H I Fakhouri, Chryl D Fryar
Data from the National Health and Nutrition Examination Survey •The prevalence of low high-density lipoprotein (HDL) cholesterol was significantly higher among adults who did not meet recommended physical activity guidelines (21.0%) than adults who met the guidelines (17.7%). •Low HDL cholesterol prevalence differed significantly for both men and women by adherence to physical activity guidelines. •Prevalence of low HDL cholesterol declined as age increased for both those who did and did not meet the physical activity guidelines...
March 2017: NCHS Data Brief
https://www.readbyqxmd.com/read/28279371/carotid-plaque-lipid-content-and-fibrous-cap-status-predict-systemic-cv-outcomes-the-mri-substudy-in-aim-high
#10
Jie Sun, Xue-Qiao Zhao, Niranjan Balu, Moni B Neradilek, Daniel A Isquith, Kiyofumi Yamada, Gádor Cantón, John R Crouse, Todd J Anderson, John Huston, Kevin O'Brien, Daniel S Hippe, Nayak L Polissar, Chun Yuan, Thomas S Hatsukami
OBJECTIVES: The aim of this study was to investigate whether and what carotid plaque characteristics predict systemic cardiovascular outcomes in patients with clinically established atherosclerotic disease. BACKGROUND: Advancements in atherosclerosis imaging have allowed assessment of various plaque characteristics, some of which are more directly linked to the pathogenesis of acute cardiovascular events compared to plaque burden. METHODS: As part of the event-driven clinical trial AIM-HIGH (Atherothrombosis Intervention in Metabolic Syndrome with Low HDL/High Triglycerides: Impact on Global Health Outcomes), subjects with clinically established atherosclerotic disease underwent multicontrast carotid magnetic resonance imaging (MRI) to detect plaque tissue composition and high-risk features...
March 2017: JACC. Cardiovascular Imaging
https://www.readbyqxmd.com/read/28274341/prevalence-of-metabolic-syndrome-and-its-components-among-patients-with-various-psychiatric-diagnoses-and-treatments-a-cross-sectional-study
#11
Fahad D Alosaimi, Mohammed Abalhassan, Bandar Alhaddad, Nasser Alzain, Ebtihaj Fallata, Abdulhadi Alhabbad, Mohammed Z Alassiry
OBJECTIVES: To evaluate the prevalence and clinical correlates of metabolic syndrome (MetS) and its components among patients with psychiatric disorders. METHODS: A cross-sectional study was conducted among adult patients with psychiatric disorders at major hospitals in Saudi Arabia. After measurements were recorded for all MetS components, demographic and clinical information was obtained mainly by reviewing the patients' medical charts. RESULTS: The prevalence rate of MetS among the 992 study participants was 41...
March 2017: General Hospital Psychiatry
https://www.readbyqxmd.com/read/28273154/leisure-time-physical-activity-sedentary-behaviors-sleep-and-cardiometabolic-risk-factors-at-baseline-in-the-predimed-plus-intervention-trial-a-cross-sectional-analysis
#12
Nuria Rosique-Esteban, Andrés Díaz-López, Miguel A Martínez-González, Dolores Corella, Albert Goday, J Alfredo Martínez, Dora Romaguera, Jesus Vioque, Fernando Arós, Antonio Garcia-Rios, Francisco Tinahones, Ramon Estruch, José Carlos Fernández-García, José Lapetra, Luís Serra-Majem, Xavier Pinto, Josep A Tur, Aurora Bueno-Cavanillas, Josep Vidal, Miguel Delgado-Rodríguez, Lidia Daimiel, Clotilde Vázquez, Miguel Ángel Rubio, Emilio Ros, Jordi Salas-Salvadó
Limited data exists on the interrelationships between physical activity (PA), sedentary behaviors and sleep concerning cardiometabolic risk factors in aged adults at high cardiovascular disease risk. Our aim was to examine independent and joint associations between time spent in leisure-time PA, sedentary behaviors and sleep on the prevalence of obesity, type 2 diabetes (T2D) and components of the metabolic syndrome (MetS) in Mediterranean individuals at high cardiovascular risk. Cross-sectional analyses were performed on baseline data from 5776 Spanish adults (aged 55-75y in men; 60-75y in women) with overweight/obesity and MetS, from October 2013 to October 2016, in the PREDIMED-PLUS trial...
2017: PloS One
https://www.readbyqxmd.com/read/28262145/predictors-of-metabolic-syndrome-in-first-manic-episode
#13
Sermin Kesebir, Boray Erdinç, Nevzat Tarhan
OBJECTIVE: In the present study we aimed to investigate, whether an association between metabolic syndrome (MetS) and clinical features and affective temperaments exists or not in first manic episode of bipolar disorder (BD) and to clarify the prevalence and predictors of MetS. METHOD: A total of 150 patients who were received a diagnosis of bipolar disorder type I according to DSM-IV criteria and who were experiencing their first manic episode (FME) were screened consecutively for inclusion...
February 2017: Asian Journal of Psychiatry
https://www.readbyqxmd.com/read/28261173/gut-microbial-diversity-assessment-of-indian-type-2-diabetics-reveals-alterations-in-eubacteria-archaea-and-eukaryotes
#14
Shrikant S Bhute, Mangesh V Suryavanshi, Suyog M Joshi, Chittaranjan S Yajnik, Yogesh S Shouche, Saroj S Ghaskadbi
Diabetes in India has distinct genetic, nutritional, developmental and socio-economic aspects; owing to the fact that changes in gut microbiota are associated with diabetes, we employed semiconductor-based sequencing to characterize gut microbiota of diabetic subjects from this region. We suggest consolidated dysbiosis of eubacterial, archaeal and eukaryotic components in the gut microbiota of newly diagnosed (New-DMs) and long-standing diabetic subjects (Known-DMs) compared to healthy subjects (NGTs). Increased abundance of phylum Firmicutes (p = 0...
2017: Frontiers in Microbiology
https://www.readbyqxmd.com/read/28258883/impact-and-attribute-of-each-obesity-related-cardiovascular-risk-factor-in-combination-with-abdominal-obesity-on-total-health-expenditures-in-adult-japanese-national-health-insurance-beneficiaries-the-ibaraki-prefectural-health-study
#15
Toshimi Sairenchi, Hiroyasu Iso, Kazumasa Yamagishi, Fujiko Irie, Masanori Nagao, Mitsumasa Umesawa, Yasuo Haruyama, Gen Kobashi, Hiroshi Watanabe, Hitoshi Ota
BACKGROUND: The aim of this study was to examine the attribution of each cardiovascular risk factor in combination with abdominal obesity (AO) on Japanese health expenditures. METHODS: The health insurance claims of 43,469 National Health Insurance beneficiaries aged 40-75 years in Ibaraki, Japan, from the second cohort of the Ibaraki Prefectural Health Study were followed-up from 2009 through 2013. Multivariable health expenditure ratios (HERs) of diabetes mellitus (DM), high low-density lipoprotein cholesterol (LDL-C), low high-density lipoprotein cholesterol (HDL-C), and hypertension with and without AO were calculated with reference to no risk factors using a Tweedie regression model...
February 28, 2017: Journal of Epidemiology
https://www.readbyqxmd.com/read/28251937/comparison-of-the-impact-of-sfas-from-cheese-and-butter-on-cardiometabolic-risk-factors-a-randomized-controlled-trial
#16
Didier Brassard, Maude Tessier-Grenier, Janie Allaire, Ethendhar Rajendiran, Yongbo She, Vanu Ramprasath, Iris Gigleux, Denis Talbot, Emile Levy, Angelo Tremblay, Peter Jh Jones, Patrick Couture, Benoît Lamarche
Background: Controversies persist concerning the association between intake of dietary saturated fatty acids (SFAs) and cardiovascular disease risk.Objective: We compared the impact of consuming equal amounts of SFAs from cheese and butter on cardiometabolic risk factors.Design: In a multicenter, crossover, randomized controlled trial, 92 men and women with abdominal obesity and relatively low HDL-cholesterol concentrations were assigned to sequences of 5 predetermined isoenergetic diets of 4 wk each separated by 4-wk washouts: 2 diets rich in SFAs (12...
March 1, 2017: American Journal of Clinical Nutrition
https://www.readbyqxmd.com/read/28251342/the-relationship-between-carbohydrate-quality-and-the-prevalence-of-metabolic-syndrome-challenges-of-glycemic-index-and-glycemic-load
#17
Mariane de Mello Fontanelli, Cristiane Hermes Sales, Antonio Augusto Ferreira Carioca, Dirce Maria Marchioni, Regina Mara Fisberg
PURPOSE: To estimate the prevalence of metabolic syndrome (MetS) and its components in adults and older adults residents of São Paulo, the association of MetS with the glycemic index (GI) and glycemic load (GL) and the foods that contribute to dietary GI and GL in this population. METHODS: Data from 591 adults and older adults participants in the Health Survey of São Paulo were used. This is a cross-sectional, population-based study with a complex multistage sample design of residents in the urban area of the municipality...
March 1, 2017: European Journal of Nutrition
https://www.readbyqxmd.com/read/28248530/correlation-of-uric-acid-levels-and-parameters-of-metabolic-syndrome
#18
Ľ Cibičková, K Langová, H Vaverková, V Kubíčková, D Karásek
Hyperuricemia has been described as associated with the risk of development metabolic syndrome; however the relationship between the uric acid level and particular parameters of metabolic syndrome remained unclear. We performed a cross-sectional study on a cohort of 833 dyslipidemic patients and correlated their levels of uric acid with parameters of insulin resistance, lipid metabolism, C-reactive protein, anthropometric parameters. We also defined patients with hypertriglyceridemic waist phenotype and compered their uric acid levels with those without this phenotype...
February 28, 2017: Physiological Research
https://www.readbyqxmd.com/read/28217266/methodology-and-early-findings-of-the-fifth-survey-of-childhood-and-adolescence-surveillance-and-prevention-of-adult-noncommunicable-disease-the-caspian-v-study
#19
Mohammad Esmaeil Motlagh, Hasan Ziaodini, Mostafa Qorbani, Majzoubeh Taheri, Tahereh Aminaei, Azam Goodarzi, Asal Ataie-Jafari, Fatemeh Rezaei, Zeinab Ahadi, Gita Shafiee, Ali Shahsavari, Ramin Heshmat, Roya Kelishadi
BACKGROUND: This paper presents the methodology and early findings of the fifth survey of a school-based surveillance program in Iran. METHODS: This nationwide study was conducted in 2015 as the fifth survey of a surveillance program entitled "Childhood and Adolescence Surveillance and PreventIon of Adult Non- communicable disease" (CASPIAN-V) study. The protocol was mainly based on the World Health Organization-Global School student Health Survey. We studied 14400 students, aged 7-18 years, and their parents living in 30 provinces in Iran...
2017: International Journal of Preventive Medicine
https://www.readbyqxmd.com/read/28214752/metabolic-syndrome-and-cardiovascular-risk-among-institutionalized-patients-with-schizophrenia-receiving-long-term-tertiary-care
#20
Lee Seng Esmond Seow, Siow Ann Chong, Peizhi Wang, Saleha Shafie, Hui Lin Ong, Mythily Subramaniam
BACKGROUND: Metabolic syndrome (MetS) and cardiovascular risk are highly prevalent among individuals with schizophrenia. This study aimed to determine the cardiometabolic profile and the associated risk factors in a group of institutionalized patients with schizophrenia or schizoaffective disorder receiving prolonged hospital care in the only tertiary psychiatric institution in Singapore. METHODS: Patients residing in long stay wards who were hospitalized for a minimum period of 1year were recruited...
February 2, 2017: Comprehensive Psychiatry
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