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https://www.readbyqxmd.com/read/29334985/role-of-sleep-duration-and-sleep-related-problems-in-the-metabolic-syndrome-among-children-and-adolescents
#1
Leonardo Pulido-Arjona, Jorge Enrique Correa-Bautista, Cesar Agostinis-Sobrinho, Jorge Mota, Rute Santos, María Correa-Rodríguez, Antonio Garcia-Hermoso, Robinson Ramírez-Vélez
BACKGROUND: There is increasing recognition that sleep is a risk factor for metabolic syndrome (MetS). The aim of the present study was to analyze the relationship between self-reported sleep duration, sleep-related problems and the presence of MetS in children and adolescents from Bogotá, D.C., Colombia. METHODS: This is a cross-sectional analysis from the FUPRECOL study (2014-15). Participants included 2779 (54.2% girls) youth from Bogota (Colombia). MetS was defined as the presence of ≥3 of the metabolic abnormalities (hyperglycemia, hypertriglyceridemia, low high-density lipoprotein cholesterol [HDL-c], hypertension, and increased waist circumference) according to the criteria of de Ferranti/Magge and colleges...
January 15, 2018: Italian Journal of Pediatrics
https://www.readbyqxmd.com/read/29330660/theobromine-consumption-does-not-improve-fasting-and-postprandial-vascular-function-in-overweight-and-obese-subjects
#2
Lotte Smolders, Ronald P Mensink, Jose J van den Driessche, Peter J Joris, Jogchum Plat
BACKGOUND: Theobromine, a component of cocoa, may favorably affect conventional lipid-related cardiovascular risk markers, but effects on flow-mediated dilation (FMD) and other vascular function markers are not known. OBJECTIVE: To evaluate the effects of 4-week theobromine consumption (500 mg/day) on fasting and postprandial vascular function markers. DESIGN: In a randomized, double-blind crossover study, 44 apparently healthy overweight (N = 30) and obese (N = 14) men and women with low HDL-C concentrations, consumed daily 500 mg theobromine or placebo for 4 weeks...
January 12, 2018: European Journal of Nutrition
https://www.readbyqxmd.com/read/29326417/factors-causing-disagreement-between-measured-and-calculated-low-density-lipoprotein-cholesterol-ldl-c-in-clinical-laboratory-services
#3
Veeravan Lekskulchai
BACKGROUND Since measured low density lipoprotein-cholesterol (LDL-C) has been available in clinical laboratories, there have been concern about the disagreement between measured and calculated LDL-C and the factors causing their disagreement. MATERIAL AND METHODS Serum lipid concentrations were collected from 1,339 medical records of patients admitted to hospital between 2013 and 2015. They were grouped by their total cholesterol (TC), triglycerides (TG), and high-density lipoprotein-cholesterol (HDL-C) concentrations and the agreement between measured and calculated LDL-C was statistically analyzed...
January 12, 2018: Medical Science Monitor Basic Research
https://www.readbyqxmd.com/read/29321358/genetic-variants-influencing-lipid-levels-and-risk-of-dyslipidemia-in-chinese-population
#4
Huaichao Luo, Xueping Zhang, Ping Shuai, Yuanying Miao, Zimeng Ye, Ying Lin
Recently, several human genetic and genomewide association studies (GWAS) have discovered many genetic loci that are associated with the concentration of the blood lipids. To confirm the reported loci in Chinese population, we conducted a crosssection study to analyse the association of 25 reported SNPs, genotyped by the ABI SNaPshot method, with the blood levels of total cholesterol (TC), low-density lipoprotein cholesterol (LDL-C), high-density lipoprotein cholesterol (HDL-C) and triglycerides (TG) in 1900 individuals by multivariate analysis...
December 2017: Journal of Genetics
https://www.readbyqxmd.com/read/29315217/association-between-dietary-pattern-and-incidence-of-cholesterolemia-in-korean-adults-the-korean-genome-and-epidemiology-study
#5
Jieul Lee, Jihye Kim
We examined the gender-specific association between dietary pattern and risk of developing cholesterolemia based on the data from the Korean Genome and Epidemiology study. A total of 7515 individuals aged 40-69 years participated in this study between 2005 and 2010. Dietary intake was assessed by a semi-quantitative food frequency questionnaire. Low HDL cholesterolemia was defined as a plasma HDL-C level <1.04 mmol/L (men) or <1.30 mmol/L (women), and high LDL cholesterolemia was defined as a plasma LDL-C level >3...
January 9, 2018: Nutrients
https://www.readbyqxmd.com/read/29301785/lp-a-lipoprotein-a-levels-predict-progression-of-carotid-atherosclerosis-in-subjects-with-atherosclerotic-cardiovascular-disease-on-intensive-lipid-therapy-an-analysis-of-the-aim-high-atherothrombosis-intervention-in-metabolic-syndrome-with-low-hdl-high-triglycerides
#6
Daniel S Hippe, Binh An P Phan, Jie Sun, Daniel A Isquith, Kevin O'Brien, John R Crouse, Todd Anderson, John Huston, Santica M Marcovina, Thomas S Hatsukami, Chun Yuan, Xue-Qiao Zhao
OBJECTIVE: To assess whether Lp(a) (lipoprotein(a)) levels and other lipid levels were predictive of progression of atherosclerosis burden as assessed by carotid magnetic resonance imaging in subjects who have been treated with LDL-C (low-density lipoprotein cholesterol)-lowering therapy and participated in the AIM-HIGH trial (Atherothrombosis Intervention in Metabolic Syndrome With Low HDL/High Triglycerides: Impact on Global Health Outcomes). APPROACH AND RESULTS: AIM-HIGH was a randomized, double-blind study of subjects with established vascular disease, elevated triglycerides, and low HDL-C (high-density lipoprotein cholesterol)...
January 4, 2018: Arteriosclerosis, Thrombosis, and Vascular Biology
https://www.readbyqxmd.com/read/29290214/dietary-management-of-dyslipidaemias-is-there-any-evidence-for-cardiovascular-benefit
#7
REVIEW
Panagiotis Anagnostis, Stavroula A Paschou, Dimitrios G Goulis, Vasilios G Athyros, Asterios Karagiannis
Specific dietary strategies are the mainstay of management in most cases of dyslipidaemia, prior to or simultaneously with the initiation of a lipid-lowering agent. The exact approach differs according to the type of dyslipidaemia. In particular, a reduction in carbohydrates (mainly foods with a high glycaemic index) and their substitution with mono- and polyunsaturated fatty acids is the main strategy in patients with high levels of triglycerides (Tg) and/or low levels of high-density lipoprotein cholesterol (HDL-c)...
February 2018: Maturitas
https://www.readbyqxmd.com/read/29280661/classical-and-emergent-cardiovascular-disease-risk-factors-in-type-2-diabetics-from-the-vallecas-area-dicariva-study
#8
Francisco J Sánchez-Muniz, Ángel García-Quismondo, Francisco Javier Del Cañizo, Juan Dorado
BACKGROUND: Type 2 diabetes mellitus (T2DM) is a major independent risk factor for cardiovascular disease (CVD) and a highly prevalent disease with a wide variety of associated metabolic disorders. OBJECTIVES: To describe features and prevalence of altered CVD risk factors in a T2DM population: DIabetes CArdiovascular RIsk of VAllecas (DICARIVA) study. PATIENTS AND METHODS: 735 adult Spanish patients of the Vallecas area with T2DM from the Infanta Leonor Hospital (Madrid, Spain) were included in the study...
November 17, 2017: Nutrición Hospitalaria: Organo Oficial de la Sociedad Española de Nutrición Parenteral y Enteral
https://www.readbyqxmd.com/read/29277345/implication-of-the-rs670-variant-of-apoa1-gene-with-lipid-profile-serum-adipokine-levels-and-components-of-metabolic-syndrome-in-adult-obese-subjects
#9
Daniel Antonio de Luis, Olatz Izaola, David Primo, Rocio Aller
BACKGROUND & AIMS: A G-to-A transition located 75 base pairs upstream (rs670) from transcription start site of the APOA1 gene is related with metabolic parameters. The aim of the present investigation was to describe the association of rs670 with metabolic syndrome and metabolic parameters. METHODS: The study involved a population of 1000 obese subjects. Measurements of anthropometric parameters, arterial blood pressure, fasting blood glucose, C-reactive protein (CRP), insulin concentration, insulin resistance (HOMA-IR), lipid profile, adipokines levels and prevalence of MetS was recorded...
December 15, 2017: Clinical Nutrition: Official Journal of the European Society of Parenteral and Enteral Nutrition
https://www.readbyqxmd.com/read/29260404/new-treatment-options-for-lipid-lowering-therapy-in-subjects-with-type-2-diabetes
#10
Roberto Scicali, Antonino Di Pino, Viviana Ferrara, Francesca Urbano, Salvatore Piro, Agata Maria Rabuazzo, Francesco Purrello
Dyslipidemias represent a variety of quantitative and/or qualitative lipoprotein abnormalities. According to etiology, we distinguish primary dyslipidemias with strictly genetic background and secondary ones with their origin in other disease or pathological states. Diabetic dyslipidemia is a type of secondary dyslipidemia and plays an important role in determining the cardiovascular risk of subjects with type 2 diabetes. In these patients, insulin resistance is responsible for overproduction and secretion of atherogenic very low density lipoprotein...
December 19, 2017: Acta Diabetologica
https://www.readbyqxmd.com/read/29249613/metabolically-healthy-and-unhealthy-weight-statuses-health-issues-and-related-costs-findings-from-the-2013-2015-european-health-examination-survey-in-luxembourg
#11
H Samouda, M Ruiz-Castell, M Karimi, V Bocquet, A Kuemmerle, A Chioti, F Dadoun, S Stranges
AIM: To investigate the relationship between metabolically healthy and unhealthy weight statuses and a wide range of related health issues, and healthcare and loss-of-productivity costs. METHODS: A total of 693 men and 729 women, aged 25-64 years, took part in the European Health Examination Survey conducted in Luxembourg between 2013 and 2015. Metabolically unhealthy normal-weight profiles were defined as having two or more cardiometabolic abnormalities (high blood pressure, high fasting glucose or triglycerides, low HDL cholesterol and/or previously diagnosed hypertension or diabetes) in people with normal weight...
December 1, 2017: Diabetes & Metabolism
https://www.readbyqxmd.com/read/29238477/prevalence-of-metabolic-syndrome-in-iran-a-meta-analysis
#12
Rahim Ostovar, Faezeh Kiani, Fatemeh Sayehmiri, Masood Yasemi, Yazdan Mohsenzadeh, Yousof Mohsenzadeh
Background: Metabolic syndrome) MetS( is a complex risk factor which increases the risk of cardiovascular diseases and type 2 diabetes. There are many studies with various populations and results about the prevalence of MetS in Iran; in order to authenticate these studies and have an overall estimation of its prevalence in Iran, performing a meta-analysis seems to be necessary. Objective: This study aimed to investigate the prevalence of MetS and its components in Iran via meta-analysis method...
October 2017: Electronic Physician
https://www.readbyqxmd.com/read/29217921/dietary-patterns-and-metabolic-syndrome-among-type-2-diabetes-patients-in-gaza-strip-palestine
#13
Abdel Hamid El Bilbeisi, Saeed Hosseini, Kurosh Djafarian
Background: The prevalence of metabolic syndrome is raising worldwide; however, the role of diet in the origin of metabolic syndrome is not understood well. This study identifies major dietary patterns among type 2 diabetes mellitus patients with and without metabolic syndrome; and its association with metabolic syndrome components in Gaza Strip, Palestine. Methods: This cross sectional study was conducted among 1200 previously diagnosed type 2 diabetes mellitus (both genders, aged 20 - 64 years) patients receiving care in primary healthcare centers in Gaza Strip, Palestine...
May 2017: Ethiopian Journal of Health Sciences
https://www.readbyqxmd.com/read/29217413/apolipoprotein-e-containing-high-density-lipoprotein-hdl-modifies-the-impact-of-cholesterol-overloaded-hdl-on-incident-coronary-heart-disease-risk-a-community-based-cohort-study
#14
Yue Qi, Jing Liu, Wei Wang, Miao Wang, Fan Zhao, Jiayi Sun, Jun Liu, Dong Zhao
BACKGROUND: Experimental studies have shown that cholesterol-overloaded high-density lipoprotein (HDL) can promote the formation of apolipoprotein E (APOE)-containing HDL, a process correcting the atherogenic function of cholesterol-overloaded HDL. OBJECTIVE: The objective of the study was to explore whether APOE-containing HDL can attenuate the defective impact of cholesterol-overloaded HDL on the development of coronary heart disease (CHD) in humans. METHODS: We measured APOE-HDL cholesterol (APOE-HDLC), HDL cholesterol (HDLC), and HDL particle number in 1112 participants aged 45 to 74 years at baseline in a community-based cohort study...
November 14, 2017: Journal of Clinical Lipidology
https://www.readbyqxmd.com/read/29212518/effect-of-low-and-high-hdl-c-levels-on-the-prognosis-of-lupus-nephritis-patients-a-prospective-cohort-study
#15
Peiran Yin, Ying Zhou, Bin Li, Lingyao Hong, Wei Chen, Xueqing Yu
BACKGROUND: Few data has been available on the effect of serum HDL-C levels on the prognosis of lupus nephritis (LN) patients. The present study therefore aimed to explore the effect of serum HDL-C levels on LN patients. METHODS: We included 775 patients with follow-up information registered in an LN database between 1 January 2006 and 31 December 2011. The patients were divided into groups with low, intermediate and high HDL-C, according to NCEP ATPIII criteria...
December 6, 2017: Lipids in Health and Disease
https://www.readbyqxmd.com/read/29212154/detection-of-susceptibility-loci-on-apoa5-and-colec12-associated-with-metabolic-syndrome-using-a-genome-wide-association-study-in-a-taiwanese-population
#16
Eugene Lin, Po-Hsiu Kuo, Yu-Li Liu, Albert C Yang, Shih-Jen Tsai
Background: Although the association of single nucleotide polymorphisms (SNPs) with metabolic syndrome (MetS) has been reported in various populations in several genome-wide association studies (GWAS), the data is not conclusive. In this GWAS study, we assessed whether SNPs are associated with MetS and its individual components independently and/or through complex interactions in a Taiwanese population. Methods: A total of 10,300 Taiwanese subjects were assessed in this study...
November 7, 2017: Oncotarget
https://www.readbyqxmd.com/read/29208626/the-effect-of-extended-release-niacin-on-markers-of-mineral-metabolism-in-ckd
#17
Rakesh Malhotra, Ronit Katz, Andrew Hoofnagle, Andrew Bostom, Dena E Rifkin, Ruth Mcbride, Jeffrey Probstfield, Geoffrey Block, Joachim H Ix
BACKGROUND AND OBJECTIVES: Niacin downregulates intestinal sodium-dependent phosphate transporter 2b expression and reduces intestinal phosphate transport. Short-term studies have suggested that niacin lowers serum phosphate concentrations in patients with CKD and ESRD. However, the long-term effects of niacin on serum phosphate and other mineral markers are unknown. DESIGN, SETTING, PARTICIPANTS, & MEASUREMENTS: The Atherothrombosis Intervention in Metabolic Syndrome with Low HDL/High Triglycerides: Impact on Global Health Trial was a randomized, double-blind, placebo-controlled trial testing extended release niacin in persons with prevalent cardiovascular disease...
January 6, 2018: Clinical Journal of the American Society of Nephrology: CJASN
https://www.readbyqxmd.com/read/29203475/hdl-particle-measurement-comparison-of-5-methods
#18
Robert Matera, Katalin V Horvath, Hari Nair, Ernst J Schaefer, Bela F Asztalos
BACKGROUND: HDL cell cholesterol efflux capacity has been documented as superior to HDL cholesterol (HDL-C) in predicting cardiovascular disease risk. HDL functions relate to its composition. Compositional assays are easier to perform and standardize than functional tests and are more practical for routine testing. Our goal was to compare measurements of HDL particles by 5 different separation methods. METHODS: HDL subfractions were measured in 98 samples using vertical auto profiling (VAP), ion mobility (IM), nuclear magnetic resonance (NMR), native 2-dimensional gel electrophoresis (2D-PAGE), and pre-β1-ELISA...
December 4, 2017: Clinical Chemistry
https://www.readbyqxmd.com/read/29198934/novel-polymorphisms-associated-with-hyperalphalipoproteinemia-and-apparent-cardioprotection
#19
Connor P Oates, Darya Koenig, Jeffrey Rhyne, Nikolay Bogush, Jeffrey O'Connell, Braxton D Mitchell, Michael Miller
BACKGROUND: Hyperalphalipoproteinemia (HALP) is inversely correlated with coronary heart disease (CHD) although genetic variants associated with high serum levels of high-density lipoprotein cholesterol (HDL-C) have not been shown to be cardioprotective. OBJECTIVE: The objective of the study was to uncover novel genetic variants associated with HALP and possibly with reduced risk of CHD. METHODS: Exome sequencing data, HDL-C, and triglyceride levels were analyzed in 1645 subjects...
November 21, 2017: Journal of Clinical Lipidology
https://www.readbyqxmd.com/read/29191416/metabolic-syndrome-in-drug-na%C3%A3-ve-schizophrenic-patients
#20
Shazia Anjum, Manish Bathla, Saminder Panchal, Gurvinder Pal Singh, Manpreet Singh
INTRODUCTION: Research in the last decade tried to focus on natural and unnatural causes of death in schizophrenic patients, but recent few years has focussed on emerging cardio-metabolic risk factors, as a cause of mortality in such patients. AIM OF THE STUDY: To assess the determinant of metabolic syndrome in drug naïve schizophrenic patients. METHODOLOGY: It was a cross sectional study; 30 indoor patients with diagnosis of schizophrenia were included...
November 24, 2017: Diabetes & Metabolic Syndrome
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