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https://www.readbyqxmd.com/read/29329623/parasite-control-strategies-used-by-equine-owners-in-the-united-states-a-national-survey
#1
M K Nielsen, M A Branan, A M Wiedenheft, R Digianantonio, L P Garber, C A Kopral, A M Phillippi-Taylor, J L Traub-Dargatz
The widespread occurrence of anthelmintic resistance in equine parasites across the world has led to recommendations of fecal egg count-based parasite programs to reduce treatment intensity and thereby delay further development of resistance as much as possible. The most recent study describing equine parasite control in the United States was conducted 20 years ago, and little is known about current strategies employed. This study was part of the National Animal Health Monitoring Systems (NAHMS) Equine 2015 Study, and aimed to describe equine parasite control strategies in the U...
January 30, 2018: Veterinary Parasitology
https://www.readbyqxmd.com/read/29324179/development-and-validation-of-an-lc-ms-ms-method-for-the-quantification-of-tiamulin-trimethoprim-tylosin-sulfadiazine-and-sulfamethazine-in-medicated-feed
#2
Ewelina Patyra, Carolina Nebot, Rosa Elvira Gavilán, Alberto Cepeda, Krzysztof Kwiatek
A new multi-compound method for the analysis of veterinary drugs, namely tiamulin, trimethoprim, tylosin, sulfadiazine and sulfamethazine was developed and validated in medicated feeds. After extraction, the samples were centrifuged, diluted in Milli-Q water, filtered and analysed by high performance liquid chromatography coupled to tandem mass spectrometry. The separation of the analytes was performed on a biphenyl column with a gradient of 0.1% formic acid in acetonitrile and 0.1% formic acid in Milli-Q water...
January 11, 2018: Food Additives & Contaminants. Part A, Chemistry, Analysis, Control, Exposure & Risk Assessment
https://www.readbyqxmd.com/read/29318621/evaluation-of-oscillometric-blood-pressure-monitor-blt-m9000-vet-in-anaesthetised-healthy-adult-dogs
#3
P Zrimšek, J Sredenšek, M Vengušt, A Seliškar
To examine agreement in anaesthetised dogs between invasive blood pressure measurements and measurements obtained with an oscillometric blood pressure monitor. MATERIALS AND METHODS: Paired invasive and oscillometric measurements were taken in 24 dogs every 5 minutes during anaesthesia (9 to 37 measurements per dog). Agreement between measurement methods was explored using Bland-Altman plots. To determine the accuracy of the oscillometric measurements, the results were compared with the guidelines recommended by the American College of Veterinary Internal Medicine and the Association for the Advancement of Medical Instrumentation...
January 10, 2018: Journal of Small Animal Practice
https://www.readbyqxmd.com/read/29290451/major-diseases-extensive-misuse-and-high-antimicrobial-resistance-of-escherichia-coli-in-large-and-small-scale-dairy-cattle-farms-in-jordan
#4
Mohammad M Obaidat, Alaa E Bani Salman, Margaret A Davis, Amira A Roess
This study aimed to determine the major diseases, antimicrobial use, and resistance in commensal Escherichia coli in dairy cattle in Jordan. Forty-three (large, n = 21; small, n = 22) farms were surveyed. A validated questionnaire was administered to the herdsmen to elicit information about disease prevalence, antimicrobial knowledge, and antimicrobial use. In addition, fecal samples were collected from 5 lactating animals on each farm. A total of 520 E. coli isolates were tested for resistance to 12 antimicrobials...
December 28, 2017: Journal of Dairy Science
https://www.readbyqxmd.com/read/29275324/use-of-clinical-vignette-questionnaires-to-investigate-the-variation-in-management-of-keratoconjunctivitis-sicca-and-acute-glaucoma-in-dogs
#5
Constance N White, Martin J Downes, Gareth Jones, Corinne Wigfall, Rachel S Dean, Marnie L Brennan
There is little peer-reviewed research assessing therapeutic effectiveness in canine eye disease. Current treatments used in first opinion and ophthalmology referral practices are also somewhat poorly documented. The aim of this study was to investigate the current management of canine keratoconjunctivitis sicca (KCS) and acute primary angle-closure glaucoma (PACG) by veterinary surgeons. Questionnaires using clinical vignettes were administered to a cross section of general practitioners ('GPs') and veterinarians engaged in or training for postgraduate ophthalmology practice ('PGs')...
December 23, 2017: Veterinary Record
https://www.readbyqxmd.com/read/29261747/sex-specific-reference-intervals-of-hematologic-and-biochemical-analytes-in-sprague-dawley-rats-using-the-nonparametric-rank-percentile-method
#6
Qili He, Guoming Su, Keliang Liu, Fangcheng Zhang, Yong Jiang, Jun Gao, Lida Liu, Zhongren Jiang, Minwu Jin, Huiping Xie
BACKGROUND: Hematologic and biochemical analytes of Sprague-Dawley rats are commonly used to determine effects that were induced by treatment and to evaluate organ dysfunction in toxicological safety assessments, but reference intervals have not been well established for these analytes. Reference intervals as presently defined for these analytes in Sprague-Dawley rats have not used internationally recommended statistical method nor stratified by sex. Thus, we aimed to establish sex-specific reference intervals for hematologic and biochemical parameters in Sprague-Dawley rats according to Clinical and Laboratory Standards Institute C28-A3 and American Society for Veterinary Clinical Pathology guideline...
2017: PloS One
https://www.readbyqxmd.com/read/29246711/validity-and-reliability-of-doppler-ultrasonography-and-direct-arterial-blood-pressure-measurements-in-anaesthetized-dogs-weighing-less-than-5-kg
#7
Xavier Moll, Adria Aguilar, Felix García, Rosa Ferrer, Anna Andaluz
OBJECTIVE: To assess the validity and reliability of Doppler ultrasonography (DOP) as compared with invasive arterial blood pressure measurements in anaesthetized dogs weighing less than 5 kg. STUDY DESIGN: Controlled, prospective, clinical study. ANIMALS: A total of 41 privately owned dogs weighing less than 5 kg. METHODS: The dogs were anaesthetized, and an intra-arterial catheter was placed aseptically in the dorsal pedal artery of the pelvic limb to perform invasive blood pressure (IBP) measurement...
September 15, 2017: Veterinary Anaesthesia and Analgesia
https://www.readbyqxmd.com/read/29244257/normal-reference-intervals-and-the-effects-of-sample-handling-on-dynamic-viscoelastic-coagulometry-sonoclot-in-healthy-adult-horses
#8
Camilla A Jamieson, Andrew S Hanzlicek, Mark E Payton, Todd C Holbrook
OBJECTIVE: To determine reference intervals and the effect of sample agitation and rest time on Sonoclot analysis in healthy adult horses. DESIGN: Original prospective study. SETTING: University veterinary medical teaching hospital. ANIMALS: Sixty healthy adult horses. INTERVENTIONS: Blood was collected for assessment of complete blood count, serum biochemical analysis, and Sonoclot analysis. MEASUREMENTS AND MAIN RESULTS: Horses were determined to be healthy based upon physical examination, CBC, and serum biochemistry analysis...
January 2018: Journal of Veterinary Emergency and Critical Care
https://www.readbyqxmd.com/read/29228960/cross-sectional-survey-on-the-use-and-impact-of-the-danish-national-antibiotic-use-guidelines-for-companion-animal-practice
#9
Lisbeth Rem Jessen, Tina Møller Sørensen, Zenia Littau Lilja, Maja Kristensen, Tine Hald, Peter Damborg
BACKGROUND: The Danish antibiotic use guidelines for companion animal practice were published by the Danish Veterinary Association in 2012. Since then, national surveillance data indicate a 10% reduction in the total use of antibiotics for companion animals, particularly a marked reduction in the use of third generation cephalosporins. The aim of the study was to assess if and how the guidelines have impacted diagnostic and antibiotic prescription habits of the users, and to identify user perceived barriers to implementation...
December 11, 2017: Acta Veterinaria Scandinavica
https://www.readbyqxmd.com/read/29224512/analytical-validation-of-cardiac-troponin-i-assays-in-horses
#10
Tanya M Rossi, Peter A Kavsak, M Grant Maxie, David L Pearl, W Glen Pyle, Peter W Physick-Sheard
Human cardiac troponin I (cTnI) assays have been used in equine medicine, often without prior analytical validation for equine use. In the absence of appropriate validation, the clinical significance of assay results is uncertain and can lead to misdiagnosis. We followed the American Society for Veterinary Clinical Pathology guidelines and investigated linearity, precision, limit of quantification (LoQ), and comparative recovery for 6 commercial cTnI assays developed for use in human medicine. Clinically acceptable linearity was observed in assays A-D, whereas assay E did not detect equine cTnI in any sample...
December 1, 2017: Journal of Veterinary Diagnostic Investigation
https://www.readbyqxmd.com/read/29196488/antimicrobial-prescribing-behaviour-in-dogs-and-cats-by-belgian-veterinarians
#11
Alexia Van Cleven, Steven Sarrazin, Hilde de Rooster, Dominique Paepe, Sofie Van der Meeren, Jeroen Dewulf
The objective of this study is to survey general prescribing behaviour by Belgian companion animal veterinarians and to assess agreement of these practices with current treatment guidelines. Therefore an online survey was administered with five realistic and frequently occurring first-line cases to primary-care veterinary practitioners. For each case a predefined pattern of questions were asked about whether or not they would prescribe antimicrobials, if they would prescribe a non-antimicrobial treatment and if they would perform additional diagnostic steps...
December 1, 2017: Veterinary Record
https://www.readbyqxmd.com/read/29188759/identifying-free-text-features-to-improve-automated-classification-of-structured-histopathology-reports-for-feline-small-intestinal-disease
#12
Abdullah Awaysheh, Jeffrey Wilcke, François Elvinger, Loren Rees, Weiguo Fan, Kurt Zimmerman
The histologic evaluation of gastrointestinal (GI) biopsies is the standard for diagnosis of a variety of GI diseases (e.g., inflammatory bowel disease [IBD] and alimentary lymphoma [ALA]). The World Small Animal Veterinary Association (WSAVA) Gastrointestinal International Standardization Group proposed a reporting standard for GI biopsies consisting of a defined set of microscopic features. We compared the machine classification accuracy of free-text microscopic findings with those represented in the WSAVA format with a diagnosis of IBD and ALA...
November 1, 2017: Journal of Veterinary Diagnostic Investigation
https://www.readbyqxmd.com/read/29177157/odds-ratio-or-prevalence-ratio-an-overview-of-reported-statistical-methods-and-appropriateness-of-interpretations-in-cross-sectional-studies-with-dichotomous-outcomes-in-veterinary-medicine
#13
Brayan Alexander Fonseca Martinez, Vanessa Bielefeldt Leotti, Gustavo de Sousa E Silva, Luciana Neves Nunes, Gustavo Machado, Luís Gustavo Corbellini
One of the most commonly observational study designs employed in veterinary is the cross-sectional study with binary outcomes. To measure an association with exposure, the use of prevalence ratios (PR) or odds ratios (OR) are possible. In human epidemiology, much has been discussed about the use of the OR exclusively for case-control studies and some authors reported that there is no good justification for fitting logistic regression when the prevalence of the disease is high, in which OR overestimate the PR...
2017: Frontiers in Veterinary Science
https://www.readbyqxmd.com/read/29169340/situational-analysis-of-antibiotic-use-and-resistance-in-ghana-policy-and-regulation
#14
Saviour Kwame Yevutsey, Kwame Ohene Buabeng, Moses Aikins, Berko Panyin Anto, Richard B Biritwum, Niels Frimodt-Møller, Martha Gyansa-Lutterodt
BACKGROUND: Antibiotics have played an essential role in decreasing morbidity and mortality from infectious diseases. However, indiscriminate use and unrestricted access is contributing to the emergence of bacterial resistance. This paper reports on a situational analysis of antimicrobial use and resistance in Ghana, with focus on policy and regulation. METHODS: Relevant policy documents, reports, regulations and enactments were reviewed. PubMed and Google search engines were used to extract relevant published papers...
November 23, 2017: BMC Public Health
https://www.readbyqxmd.com/read/29157372/prevalence-of-antimicrobial-resistance-from-bacterial-culture-and-susceptibility-records-from-horse-samples-in-south-africa
#15
John K Chipangura, Thireshni Chetty, Marcia Kgoete, Vinny Naidoo
The continuous increase in prevalence of antimicrobial resistant bacteria presents a significant public health problem and is an indicator that antimicrobial prudent usage guidelines are not being followed, especially in developing countries. Despite trends being available from numerous countries, there is little published for South Africa. This study was aimed at estimating the prevalence and trends of antimicrobial resistance from bacterial isolates from equine clinical samples submitted for culture and susceptibility testing to the veterinary bacteriology laboratory of the University of Pretoria...
December 1, 2017: Preventive Veterinary Medicine
https://www.readbyqxmd.com/read/29124058/implementation-of-a-regional-training-program-on-african-swine-fever-as-part-of-the-cooperative-biological-engagement-program-across-the-caucasus-region
#16
Marco De Nardi, Anaïs Léger, Tatul Stepanyan, Bagrat Khachatryan, Talgat Karibayev, Igor Sytnik, Samat Tyulegenov, Assel Akhmetova, Serhiy Nychyk, Mykola Sytiuk, Oleg Nevolko, Roman Datsenko, Tengiz Chaligava, Lasha Avaliani, Otar Parkadze, Lena Ninidze, Natia Kartskhia, Tsira Napetvaridze, Zviad Asanishvili, Demna Khelaia, Ioseb Menteshashvili, Meruzhan Zadayan, Lyudmila Niazyan, Nataliya Mykhaylovska, Bradford Raymond Brooks, Gulnara Zhumabayeva, Saltanat Satabayeva, Magda Metreveli, Theresa Gallagher, Richard Obiso
A training and outreach program to increase public awareness of African swine fever (ASF) was implemented by Defense Threat Reduction Agency and the Ministries of Agriculture in Armenia, Georgia, Kazakhstan, and Ukraine. The implementing agency was the company SAFOSO (Switzerland). Integration of this regional effort was administered by subject matter experts for each country. The main teaching effort of this project was to develop a comprehensive regional public outreach campaign through a network of expertise and knowledge for the control and prevention of ASF in four neighboring countries that experience similar issues with this disease...
2017: Frontiers in Veterinary Science
https://www.readbyqxmd.com/read/29119445/guidelines-for-bacteriophage-product-certification
#17
Alan Fauconnier
Following decades in the wilderness, bacteriophage therapy is now appearing as a credible antimicrobial strategy. However, this reemerging therapy does not rekindle without raising sensitive regulatory concerns. Indeed, whereas the European regulatory framework has been basically implemented to tackle ready-to-use pharmaceuticals produced on a large scale, bacteriophage therapy relies on a dynamic approach requiring a regulation on personalized medicine, nonexistent at present. Because of this, no guideline are currently available for addressing the scientific and regulatory issues specifically related to phage therapy medicinal products (PTMP)...
2018: Methods in Molecular Biology
https://www.readbyqxmd.com/read/29102325/surveillance-for-control-of-antimicrobial-resistance
#18
REVIEW
Evelina Tacconelli, Frangiscos Sifakis, Stephan Harbarth, Remco Schrijver, Maaike van Mourik, Andreas Voss, Mike Sharland, Nithya Babu Rajendran, Jesús Rodríguez-Baño
Antimicrobial resistance poses a growing threat to public health and the provision of health care. Its surveillance should provide up-to-date and relevant information to monitor the appropriateness of therapy guidelines, antibiotic formulary, antibiotic stewardship programmes, public health interventions, infection control policies, and antimicrobial development. In Europe, although the European Antimicrobial Resistance Surveillance Network provides annual reports on monitored resistant bacteria, national surveillance efforts are still fragmented and heterogeneous, and have substantial structural problems and issues with laboratory data...
October 25, 2017: Lancet Infectious Diseases
https://www.readbyqxmd.com/read/29102120/antimicrobial-resistance-in-clinical-escherichia-coli-isolated-from-companion-animals-in-australia
#19
Sugiyono Saputra, David Jordan, Tahlia Mitchell, Hui San Wong, Rebecca J Abraham, Amanda Kidsley, John Turnidge, Darren J Trott, Sam Abraham
Multidrug-resistant (MDR) Escherichia coli have become a major public health concern to both humans and animal health. While the frequency of antimicrobial resistance (AMR) in clinical E. coli is monitored regularly in human medicine, current frequency of AMR in companion animals remains unknown in Australia. In this study we conducted antimicrobial susceptibility testing (AST) and where possible, determined potential risk factors for MDR infection among 883 clinical Escherichia coli isolated from dogs (n=514), cats (n=341) and horses (n=28)...
November 2017: Veterinary Microbiology
https://www.readbyqxmd.com/read/29076657/safety-profile-of-a-replication-deficient-human-adenovirus-vectored-foot-and-mouth-disease-virus-serotype-a24-subunit-vaccine-in-cattle
#20
J Barrera, D A Brake, B J Kamicker, C Purcell, R Kaptur, T Schieber, K Lechtenberg, T D Miller, D Ettyreddy, D E Brough, B T Butman, M Colby, J G Neilan
The safety of a replication-deficient, human adenovirus-vectored foot-and-mouth disease virus (FMDV) serotype A24 Cruzeiro capsid-based subunit vaccine (AdtA24) was evaluated in five independent safety studies. The target animal safety studies were designed in compliance with United States (U.S.) regulatory requirements (Title 9, U.S. Code of Federal Regulation [9CFR]) and international standard guidelines (VICH Topic GL-44) for veterinary live vaccines. The first three studies were conducted in a total of 22 vaccinees and demonstrated that the AdtA24 master seed virus (MSV) was safe, did not revert to virulence and was not shed or spread from vaccinees to susceptible cattle or pigs...
October 27, 2017: Transboundary and Emerging Diseases
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