keyword
https://read.qxmd.com/read/38519808/efficacy-of-intravenous-iron-in-patients-with-heart-failure-with-reduced-ejection-fraction-and-iron-deficiency-a-systematic-review-and-meta-analysis-of-randomized-control-trials
#21
Andrew Sephien, Denisse Camille Dayto, Tea Reljic, Xavier Prida, Joanna M Joly, Matthew Tavares, Jason N Katz, Ambuj Kumar
BACKGROUND: The European Society of Cardiology (ESC) provided a focused update to the 2021 Guideline for the Management of Heart Failure, now providing a 1A recommendation for intravenous iron in patients with heart failure with reduced ejection fraction (HFrEF) and iron deficiency (ID). However, the findings from randomized controlled trials (RCT) are mixed. This systematic review of RCTs aims to provide an update and synthesize the evidence addressing the association of intravenous iron with patient-based outcomes in patients with HFrEF and ID...
March 22, 2024: American Journal of Cardiovascular Drugs: Drugs, Devices, and Other Interventions
https://read.qxmd.com/read/38519765/the-role-of-echocardiography-in-pulmonary-embolism-for-the-prediction-of-in-hospital-mortality-a-retrospective-study
#22
JOURNAL ARTICLE
Michele Domenico Spampinato, Andrea Portoraro, Soccorsa M Sofia, Francesco Luppi, Marcello Benedetto, Luca D'Angelo, Giorgio Galizia, Irma Sofia Fabbri, Teresa Pagano, Benedetta Perna, Matteo Guarino, Giulia Passarini, Rita Pavasini, Angelina Passaro, Roberto De Giorgio
PURPOSE: Pulmonary Embolism (PE) is the third leading cause of cardiovascular death, following myocardial infarction and stroke. The latest European Society of Cardiology (ESC) guidelines on PE recommend short-term prognostic stratification based on right ventricular (RV) overload detected by transthoracic echocardiography (TTE) or contrast-enhanced chest CT. The aim of the study is to find out which of the signs of right ventricular dysfunction best predicts in-hospital mortality (IHM)...
March 23, 2024: Journal of Ultrasound
https://read.qxmd.com/read/38517999/the-impact-of-the-2019-esc-eas-dyslipidaemia-guidelines-on-real-world-initial-lipid-lowering-therapy-in-patients-with-acute-myocardial-infarction
#23
JOURNAL ARTICLE
Xiangqi Kong, Gang He, Xiaoqing Quan, Zhixiong Tan, Fengjuan Yan, Xiehui Chen
This study aimed to investigate the impact of the latest guidelines on the real-world clinical practice of initial lipid-lowering therapy, especially on the use of ezetimibe and proprotein convertase subtilisin/kexin type 9 (PCSK9) inhibitors in China. All adult patients diagnosed with acute myocardial infarction in our hospital between August 31, 2018, and August 31, 2020, were divided into the following 2 groups: those patients treated before the latest guideline release, and those patients treated after the release...
March 22, 2024: Medicine (Baltimore)
https://read.qxmd.com/read/38517604/assessing-regurgitation-severity-adverse-remodeling-and-fibrosis-with-cmr-in-aortic-regurgitation
#24
REVIEW
Mujtaba Saeed, Akila Bersali, Amr Darwish, Fatima Qamar, Dimitrios Maragiannis, Kinan Carlos El-Tallawi, Maan Malahfji, Dipan J Shah
PURPOSE OF REVIEW: Cardiac magnetic resonance (CMR) is emerging as a valuable imaging modality for the assessment of aortic regurgitation (AR). In this review, we discuss the assessment of AR severity, left ventricular (LV) remodeling, and tissue characterization by CMR while highlighting the latest studies and addressing future research needs. RECENT FINDINGS: Recent studies have further established CMR-based thresholds of AR severity and LV remodeling that are associated with adverse clinical outcomes, and lower than current guideline criteria...
March 22, 2024: Current Cardiology Reports
https://read.qxmd.com/read/38517528/-angina-and-no-obstruction-on-coronary-angiography-new-approaches-to-the-diagnosis-and-treatment-of-vasomotor-disorders
#25
REVIEW
Peter Ong, Tanja K Rudolph, Jens Wiebe, Rudolf Berger, Felix Woitek, Ulf Landmesser
BACKGROUND: Clinical management of patients with angina and no obstructive coronary artery disease (ANOCA) is still challenging. This scenario affects up to 50% of patients undergoing diagnostic coronary angiography due to suspected coronary artery disease. Many patients report a long and debilitating history before adequate diagnostics and management are initiated. OBJECTIVES: This article describes the current recommendations for diagnostic assessments and treatment in patients with ANOCA...
March 22, 2024: Inn Med (Heidelb)
https://read.qxmd.com/read/38517253/ultra-early-hemostatic-therapy-for-acute-intracerebral-hemorrhage-an-updated-review
#26
JOURNAL ARTICLE
Michael Fortunato, Galadu Subah, Anish D Thomas, Bridget Nolan, Monica Mureb, Anaz Uddin, Kiran Upadhyay, Jonathan V Ogulnick, Nitesh Damodara, Colleen Bond, Chirag D Gandhi, Stephan A Mayer, Fawaz Al-Mufti
Intracerebral hemorrhage (ICH) is the second most common type of stroke, accounting for approximately 10-20% of all strokes, and is linked to severe neurological disability and death. Since the most accurate predictor of outcome in patients with ICH is hematoma volume, there is a great need for pharmacologic therapy that can reduce hematoma expansion and resultant mass effect and edema. This is especially critical within the ultra-early window of 3-4 hours after the presentation. Hemostatic therapies are exceptionally important for those patients taking antiplatelet or anticoagulant medications to reverse the effects of these medications and therefore prevent hematoma expansion...
March 21, 2024: Cardiology in Review
https://read.qxmd.com/read/38516780/clinical-guideline-for-preimplantation-genetic-testing-in-inherited-cardiac-diseases
#27
JOURNAL ARTICLE
Job A J Verdonschot, Debby M E I Hellebrekers, Vanessa P M van Empel, Malou Heijligers, Sonja de Munnik, Edith Coonen, Jos C M F Dreesen, Arthur van den Wijngaard, Han G Brunner, Masoud Zamani Esteki, Stephane R B Heymans, Christine E M de Die-Smulders, Aimée D C Paulussen
BACKGROUND: Preimplantation genetic testing (PGT) is a reproductive technology that selects embryos without (familial) genetic variants. PGT has been applied in inherited cardiac disease and is included in the latest American Heart Association/American College of Cardiology guidelines. However, guidelines selecting eligible couples who will have the strongest risk reduction most from PGT are lacking. We developed an objective decision model to select eligibility for PGT and compared its results with those from a multidisciplinary team...
March 22, 2024: Circulation. Genomic and Precision Medicine
https://read.qxmd.com/read/38515385/physician-perceptions-attitudes-and-strategies-towards-implementing-guideline-directed-medical-therapy-in-heart-failure-with-reduced-ejection-fraction-a-survey-of-the-heart-failure-association-of-the-esc-and-the-esc-council-for-cardiology-practice
#28
JOURNAL ARTICLE
Gianluigi Savarese, Felix Lindberg, Ruxandra M Christodorescu, Marc Ferrini, Thomas Kumler, Konstantinos Toutoutzas, Giuseppe Dattilo, Antoni Bayes-Genis, Brenda Moura, Offer Amir, Mark C Petrie, Petar Seferovic, Ovidiu Chioncel, Marco Metra, Andrew J S Coats, Giuseppe M C Rosano
AIMS: Recent guidelines recommend four core drug classes (renin-angiotensin system/angiotensin receptor-neprilysin inhibitor [RASi/ARNi], beta-blocker, mineralocorticoid receptor antagonist [MRA], and sodium-glucose cotransporter 2 inhibitor [SGLT2i]) for the pharmacological management of heart failure (HF) with reduced ejection fraction (HFrEF). We assessed physicians' perceived (i) comfort with implementing the recent HFrEF guideline recommendations; (ii) status of guideline-directed medical therapy (GDMT) implementation; (iii) use of different GDMT sequencing strategies; and (iv) barriers and strategies for achieving implementation...
March 22, 2024: European Journal of Heart Failure
https://read.qxmd.com/read/38514339/-chinese-expert-consensus-on-antithrombotic-therapy-of-panvascular-diseases-2024-edition
#29
JOURNAL ARTICLE
(no author information available yet)
Panvascular disease is a systemic condition with vascular lesions (95% of which are atherosclerosis) as the common pathological feature, which can be manifested as coronary artery disease, cerebrovascular disease, peripheral artery disease, etc., or a combination of two or more vascular bed diseases that is called multivascular disease. The burden of panvascular diseases in China is heavy, and improvement of patient prognosis is urgently needed. Although the management of panvascular diseases belongs to different disciplines, they often share common risk factors and pathophysiological mechanisms that warrant standardized treatment strategies...
March 26, 2024: Zhonghua Yi Xue za Zhi [Chinese medical journal]
https://read.qxmd.com/read/38513737/clinical-characteristics-treatment-trajectories-and-outcome-of-patients-with-dilated-cardiomyopathy-in-a-national-heart-failure-registry
#30
JOURNAL ARTICLE
Samuela Carigi, Piero Gentile, Mauro Gori, Denitza Tinti, Luisa De Gennaro, Giuseppe Leonardi, Francesco Orso, Anna Rita Felici, Maria Rosaria Catalano, Marina Floresta, Vittoria Rizzello, Donata Lucci, Lucio Gonzini, Renata De Maria, Marco Marini
BACKGROUND: Available data on the clinical characteristics and prognosis of patients with heart failure (HF) due to dilated cardiomyopathy (DCM) derive mainly from tertiary care centres for cardiomyopathies or from drug trial sub-studies, which may entail a referral bias. METHODS: From 2008 to 2021, we enrolled in a nationwide HF Registry 1886 DCM patients and 3899 with ischemic heart disease (IHD). RESULTS: Patients with DCM were younger, more often female, had more commonly recent onset HF, left bundle branch block, and showed higher LV end-diastolic volume and lower LVEF than IHD...
March 19, 2024: International Journal of Cardiology
https://read.qxmd.com/read/38513735/raw-data-were-not-disclosed-in-95-of-pubmed-indexed-heart-failure-meta-analyses-in-2021-a-systematic-analysis-of-transparency
#31
JOURNAL ARTICLE
Panagiotis Karakitsos, Konstantinos S Mylonas
BACKGROUND: The rising concern of irreproducible and non-transparent studies poses a significant challenge in modern medical literature. The impact of this issue on cardiology, particularly in the subfield of heart failure, remains poorly understood. To address this knowledge gap, we assessed the quality of evidence presented in recent heart failure meta-analyses by exploring several crucial transparency indicators. METHODS: We conducted a cross-sectional study and searched PubMed for meta - analyses themed around heart failure...
March 19, 2024: International Journal of Cardiology
https://read.qxmd.com/read/38513622/treatment-of-chronic-heart-failure-in-advanced-chronic-kidney-disease-the-haka-multicenter-retrospective-real-world-study
#32
JOURNAL ARTICLE
Borja Quiroga, Alberto Ortiz, Sara Núñez, Maria Kislikova, Silvia González Sanchidrián, José Jesús Broseta, Zoila Stany Albines, Beatriz Escamilla Cabrera, Yaiza Rivero Viera, David Rodriguez Santarelli, Laura Salanova Villanueva, Francisca Lopez Rodriguez, Barbara Cancho Castellano, María Ibáñez Cerezon, Carmen Patricia Gutierrez Rivas, Nuria Aresté, Belén Campos Gutiérrez, Ana Ródenas Gálvez, Maria Constanza Glucksmann Pizá, Sagrario Balda Manzanos, Amparo Soldevila, Lucía Rodríguez Gayo, Esperanza Moral Berrio, Mayra Ortega Diaz, Sandra Beltrán Catalán, Adriana Puente García, Miguel Ángel Rojas, R Haridian Sosa Barrios, Henar Santana Zapatero, Gema Rangel Hidalgo, Ana Maria Martinez Canet, Javier Díez
INTRODUCTION: Chronic heart failure (HF) has high rates of mortality and hospitalization in patients with advanced chronic kidney disease (aCKD). However, randomized clinical trials have systematically excluded aCKD population. We have investigated current HF therapy in patients receiving clinical care in specialized aCKD units. METHODS: The Heart And Kidney Audit (HAKA) was a cross-sectional and retrospective real-world study including outpatients with aCKD and HF from 29 Spanish centers...
March 21, 2024: Cardiorenal Medicine
https://read.qxmd.com/read/38513366/effect-of-heart-failure-pharmacotherapies-in-patients-with-heart-failure-with-mildly-reduced-ejection-fraction
#33
JOURNAL ARTICLE
Tobias Schupp, Thomas Bertsch, Marielen Reinhardt, Noah Abel, Alexander Schmitt, Felix Lau, Mohammad Abumayyaleh, Muharrem Akin, Christel Weiß, Kathrin Weidner, Michael Behnes, Ibrahim Akin
OBJECTIVE: The study sought to comprehensively investigate the effect of heart failure (HF) pharmacotherapies in patients with heart failure with mildly reduced ejection fraction (HFmrEF). BACKGROUND: In the absence of randomized controlled trials, guideline recommendations concerning HF-related therapies in patients with HFmrEF are limited. METHODS: Consecutive patients hospitalized with HFmrEF were retrospectively included at one institution from 2016 to 2022...
March 21, 2024: European Journal of Preventive Cardiology
https://read.qxmd.com/read/38510995/clinical-course-of-adults-with-co-occurring-hypertrophic-cardiomyopathy-and-hypertension-a-scoping-review
#34
REVIEW
Milla Arabadjian, Sophie Montgomery, Mitchell Pleasure, Barnaby Nicolas, Maxine Collins, Maria Reuter, Daniele Massera, Daichi Shimbo, Mark V Sherrid
INTRODUCTION: Hypertension affects approximately 50 % of patients with hypertrophic cardiomyopathy (HCM) but clinical course in adults with co-occurring HCM and hypertension is underexplored. Management may be challenging as routine anti-hypertensive medications may worsen obstructive HCM, the most common HCM phenotype. In this scoping review, we sought to synthesize the available literature related to clinical course and outcomes in adults with both conditions and to highlight knowledge gaps to inform future research directions...
March 2024: American heart journal plus: cardiology research and practice
https://read.qxmd.com/read/38510948/a-randomized-controlled-trial-evaluating-a-theory-driven-complex-intervention-centered-on-task-sharing-and-mobile-health-to-improve-selfcare-and-outcomes-in-heart-failure-the-panacea-hf-rct-design-and-rationale
#35
JOURNAL ARTICLE
D Y Kamath, J Abdullakutty, B B Granger, S Kulkarni, K B Bhuvana, L J Salazar, S Shifra, J Idiculla, J Narendra, K Varghese, D Xavier
BACKGROUND: We developed a three-pronged complex intervention to improve selfcare and deliver whole person care for patients with heart failure, underpinned by the 'extant cycle' theory - a theory based on our formative work. METHODS: This is a 3 centre, 2-arm, 1:1, open, adaptive stratified, randomized controlled trial. We included patients aged ≥ 18 years with heart failure, taking any of the key guideline directed medical treatments, with a history of or currently on a high ceiling diuretic...
October 2023: American heart journal plus: cardiology research and practice
https://read.qxmd.com/read/38510745/impact-of-nurse-led-interprofessional-work-in-older-patients-with-heart-failure-and-multimorbidity-a-retrospective-cohort-study
#36
JOURNAL ARTICLE
Yuichiro Saizen, Kasumi Ikuta, Mizuki Katsuhisa, Yuko Takeshita, Yuki Moriki, Misaki Kasamatsu, Mai Onishi, Kiyoko Wada, Chiharu Honda, Kyoko Nishimoto, Yoshiko Nabetani, Tomoyuki Iwasaki, Eriko Koujiya, Miyae Yamakawa, Yasushi Takeya
BACKGROUND: The number of patients with multimorbidity has increased due to the aging of the global population. Although the World Health Organization has indicated that multimorbidity will be a major medical problem in the future, the appropriate interventions for patients with multimorbidity are currently unknown. This study aimed to investigate whether nurse-led interprofessional work is associated with improved prognosis in heart failure patients with multimorbidity aged ≥65 years who were admitted in an acute care hospital...
February 2024: American heart journal plus: cardiology research and practice
https://read.qxmd.com/read/38510744/prognostic-differences-between-physiology-guided-percutaneous-coronary-intervention-and-optimal-medical-therapy-in-coronary-artery-disease-a-systematic-review-and-meta-analysis
#37
REVIEW
Utsho Islam, Muhammad Sabbah, Burcu T Özbek, Jasmine M Madsen, Jacob T Lønborg, Thomas Engstrøm
BACKGROUND: Intracoronary physiology, particularly fractional flow reserve (FFR), has been used as a guide for revascularization for patients with coronary artery disease (CAD). The optimal treatment in the physiological grey-zone area has been unclear and remains subject to ongoing debate. METHODS: We conducted a systematic review of randomized controlled trials and observational studies comparing the prognostic effect of percutaneous coronary revascularization (PCI) and optimal medical therapy (OMT) in patients with CAD...
February 2024: American heart journal plus: cardiology research and practice
https://read.qxmd.com/read/38510299/impact-of-the-esc-cardio-oncology-guidelines-biomarker-criteria-on-incidence%C3%A2-of-cancer-therapy-related-cardiac-dysfunction
#38
JOURNAL ARTICLE
Albulena Mecinaj, Geeta Gulati, Anne Hansen Ree, Berit Gravdehaug, Helge Røsjø, Kjetil Steine, Torbjørn Wisløff, Jürgen Geisler, Torbjørn Omland, Siri Lagethon Heck
BACKGROUND: The impact of recent consensus definitions of cancer therapy-related cardiac dysfunction (CTRCD) from the European Society of Cardiology cardio-oncology guidelines on the reported incidence of CTRCD has not yet been assessed. OBJECTIVES: The aim of this study was to assess the: 1) cumulative incidence; 2) point prevalence during and after adjuvant therapy; and 3) prognostic value of CTRCD as defined by different asymptomatic CTRCD guideline criteria...
February 2024: JACC CardioOncology
https://read.qxmd.com/read/38508307/bridging-gaps-the-urgent-call-for-cardio-obstetrics-as-a-subspecialty-in-india
#39
REVIEW
Justin Paul Gnanaraj, Steaphen Anne Princy
Cardiovascular disease complicates 1-4% of pregnancies. Women with heart disease going through pregnancy are on the increase. While global maternal deaths during pregnancy are decreasing, India remains a significant contributor to maternal deaths in the world. Cardiovascular disease during pregnancy is the leading cause of maternal mortality in developed nations, and this trend is expected soon in India, with the ongoing obstetric transition. Research in developed nations indicates that a high proportion of maternal mortality related to heart disease is preventable...
March 18, 2024: Indian Heart Journal
https://read.qxmd.com/read/38506918/preliminary-evidence-of-the-use-of-generative-ai-in-health-care-clinical-services-systematic-narrative-review
#40
REVIEW
Dobin Yim, Jiban Khuntia, Vijaya Parameswaran, Arlen Meyers
BACKGROUND: Generative artificial intelligence tools and applications (GenAI) are being increasingly used in health care. Physicians, specialists, and other providers have started primarily using GenAI as an aid or tool to gather knowledge, provide information, train, or generate suggestive dialogue between physicians and patients or between physicians and patients' families or friends. However, unless the use of GenAI is oriented to be helpful in clinical service encounters that can improve the accuracy of diagnosis, treatment, and patient outcomes, the expected potential will not be achieved...
March 20, 2024: JMIR Medical Informatics
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