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JOURNAL ARTICLE
Abel A Pavía-López, José A Magaña-Serrano, José A Cigarroa-López, Adolfo Chávez-Mendoza, José L Mayorga-Butrón, Diego Araiza-Garaygordobil, Juan B Ivey-Miranda, Gustavo F Méndez-Machado, Héctor González-Godínez, Luisa F Aguilera-Mora, Antonio Jordán-Ríos, Luis Olmos-Domínguez, Marcos J Olalde-Román, Emma M Miranda-Malpica, Zuilma Vázquez-Ortiz, Jorge Rayo-Chávez, Alexandra A Mendoza, Manlio F Márquez-Murillo, Sergio A Chávez-Leal, Amada Álvarez-San Gabriel, Marissa A Silva-García, Alex D Pacheco-Bouthiller, Jorge A Aldrete-Velazco, Carlos A Guizar-Sánchez, Efraín Gaxiola-López, Arturo Guerra-López, Lourdes Figueiras-Graillet, Gustavo Sánchez-Miranda, Genaro H Mendoza-Zavala, Moisés Aceves-García, Adolfo Chávez-Negrete, Marisol Arroyo-Hernández, Bertha B Montaño-Velázquez, Luis F Romero-Moreno, María M Baquero-Hoyos, Liliana Velasco-Hidalgo, Ana L Rodríguez-Lozano, Nancy E Aguilar-Gómez, Mario Rodríguez-Vega, Jorge E Cossío-Aranda
Chronic heart failure continues to be one of the main causes of impairment in the functioning and quality of life of people who suffer from it, as well as one of the main causes of mortality in our country and around the world. Mexico has a high prevalence of risk factors for developing heart failure, such as high blood pressure, diabetes, and obesity, which makes it essential to have an evidence-based document that provides recommendations to health professionals involved in the diagnosis and treatment of these patients...
2024: Archivos de Cardiología de México
#2
JOURNAL ARTICLE
Alexis R Bogannam, Ewan McNicol, Kevin DeLeonardo, Ashwini Ranade, Kathy Zaiken
Background: Recent clinical trials and guideline updates have highlighted the efficacy and safety of sodium-glucose cotransporter-2 inhibitor (SGLT2i) use in patients with type 2 diabetes (T2D) and comorbidities including atherosclerotic cardiovascular disease (ASCVD), chronic kidney disease (CKD), or heart failure (HF). Objective: This study assesses the rates of guideline-based prescribing of SGLT2i in patients with T2D and one or more of the following comorbidities: ASCVD, CKD, or HF, prior to and after the 2022 American Diabetes Association (ADA) guideline publication within the Atrius Health clinical pharmacy, internal medicine, and specialty medicine departments...
April 22, 2024: Journal of Pharmacy Practice
#3
JOURNAL ARTICLE
Jack Barrington, Zaheer Yousef, Christian Peter Subbe
The number of people using wearable technology such as smartwatches and fitness trackers is increasing. Many of these devices can alert the user to a potential arrhythmia such as atrial fibrillation. We aimed to assess potential changes to cardiology practice resulting from their use. An online questionnaire consisting of 12 questions was created and distributed to all consultant cardiologists in Wales. 25 of 102 participants replied, with 92% of these using consumer wearable technology to diagnose atrial fibrillation either 'often' or 'sometimes'...
March 2024: Future Healthcare Journal
#4
REVIEW
Gissette Reyes-Soffer, Calvin Yeang, Erin D Michos, Wess Boatwright, Christie M Ballantyne
High levels of lipoprotein(a) [Lp(a)] are causal for atherosclerotic cardiovascular disease (ASCVD). Lp(a) is the most prevalent inherited dyslipidemia and strongest genetic ASCVD risk factor. This risk persists in the presence of at target, guideline-recommended, LDL-C levels and adherence to lifestyle modifications. Epidemiological and genetic evidence supporting its causal role in ASCVD and calcific aortic stenosis continues to accumulate, although various facets regarding Lp(a) biology (genetics, pathophysiology, and expression across race/ethnic groups) are not yet fully understood...
June 2024: American journal of preventive cardiology
#5
JOURNAL ARTICLE
Min Chul Kim, Joon Ho Ahn, Dae Young Hyun, Yongwhan Lim, Seung Hun Lee, Seok Oh, Kyung Hoon Cho, Doo Sun Sim, Young Joon Hong, Ju Han Kim, Myung Ho Jeong, Jang Hyun Cho, Sang-Rok Lee, Dong Oh Kang, Jin-Yong Hwang, Young Jin Youn, Young-Hoon Jeong, Yongwhi Park, Dong-Bin Kim, Eun-Ho Choo, Chan Joon Kim, Weon Kim, Jay Young Rhew, Jung-Hee Lee, Sang-Yong Yoo, Youngkeun Ahn
BACKGROUND: Current guidelines recommend complete revascularization (CR) in hemodynamically stable patients with ST-segment elevation myocardial infarction (STEMI) and multivessel coronary artery disease (MVD). With regard to the timing of percutaneous coronary intervention (PCI) for non-infarct-related artery (non-IRA), recent randomized clinical trials have revealed that immediate CR was non-inferior to staged CR. However, the optimal timing of CR remains uncertain. The OPTION-STEMI trial compared immediate CR and in-hospital staged CR guided by fractional flow reserve (FFR) for intermediate stenosis of the non-IRA...
April 17, 2024: American Heart Journal
#6
JOURNAL ARTICLE
Hanjin Park, Daehoon Kim, Seng Chan You, Eunsun Jang, Hee Tae Yu, Tae-Hoon Kim, Dong-Min Kim, Jung-Hoon Sung, Hui-Nam Pak, Moon-Hyoung Lee, Pil-Sung Yang, Boyoung Joung
BACKGROUND: A study was designed to investigate whether the coronary artery disease polygenic risk score (CAD-PRS) may guide lipid-lowering treatment initiation as well as deferral in primary prevention beyond established clinical risk scores. METHODS AND RESULTS: Participants were 311 799 individuals from the UK Biobank free of atherosclerotic cardiovascular disease, diabetes, chronic kidney disease, and lipid-lowering treatment at baseline. Participants were categorized as statin indicated, statin indication unclear, or statin not indicated as defined by the European and US guidelines on statin use...
April 19, 2024: Journal of the American Heart Association
#7
JOURNAL ARTICLE
Cyprien A Rivier, Julian N Acosta, Audrey C Leasure, Rachel Forman, Richa Sharma, Adam de Havenon, Erica S Spatz, Silvio E Inzucchi, Walter N Kernan, Guido J Falcone, Kevin N Sheth
BACKGROUND: The implementation of preventive therapies among patients with stroke remains inadequately explored, especially when compared with patients with myocardial infarction (MI), despite sharing similar vascular risk profiles. We tested the hypothesis that participants with a history of stroke have a worse cardiovascular prevention profile in comparison to participants with MI. METHODS AND RESULTS: In cross-sectional analyses within the UK Biobank and All of Us Research Program, involving 14 760 (9193 strokes, 5567 MIs) and 7315 (2948 strokes, 4367 MIs) participants, respectively, we evaluated cardiovascular prevention profiles assessing low-density lipoprotein (<100 mg/dL), blood pressure (systolic, <140 mm Hg; and diastolic, <90 mm Hg), statin and antiplatelet use, and a cardiovascular prevention score that required meeting at least 3 of these criteria...
April 19, 2024: Journal of the American Heart Association
#8
JOURNAL ARTICLE
Nina Strandkjær, Nicoline Jørgensen, Rasmus Bo Hasselbalch, Jonas Kristensen, Marie Sophie Sander Knudsen, Thilde Olivia Kock, Theis Lange, Matias Greve Lindholm, Niels Eske Bruun, Lene Holmvang, Christian Juhl Terkelsen, Claus Kjær Pedersen, Martin Kirk Christensen, Jens Flensted Lassen, Linda Hilsted, Søren Ladefoged, Mads Nybo, Mustafa Vakur Bor, Morten Dahl, Annebirthe Bo Hansen, Pia Rørbæk Kamstrup, Henning Bundgaard, Christian Torp-Pedersen, Kasper Karmark Iversen
BACKGROUND: Cardiac troponins are the preferred biomarkers for the diagnosis of acute myocardial infarction. Although sex-specific 99th percentile thresholds of troponins are recommended in international guidelines, the clinical effect of their use is poorly investigated. The DANSPOT Study (The Danish Study of Sex- and Population-Specific 99th percentile upper reference limits of Troponin) aims to evaluate the clinical effect of a prospective implementation of population- and sex-specific diagnostic thresholds of troponins into clinical practice...
April 19, 2024: Journal of the American Heart Association
#9
JOURNAL ARTICLE
Pi-I Debby Lin, Sheryl Rifas-Shiman, John Merriman, Joshua Petimar, Han Yu, Matthew F Daley, David M Janicke, William J Heerman, L Charles Bailey, Carlos Maeztu, Jessica Young, Jason P Block
BACKGROUND: Guidelines for the use of antihypertensives changed in 2014 and 2017. To understand the effect of these guidelines, we examined trends in antihypertensive prescriptions in the United States from 2010 to 2019 using a repeated cross-sectional design. METHODS AND RESULTS: Using electronic health records from 15 health care institutions for adults (20-85 years old) who had ≥1 antihypertensive prescription, we assessed whether (1) prescriptions of beta blockers decreased after the 2014 Eighth Joint National Committee (JNC 8) report discouraged use for first-line treatment, (2) prescriptions for calcium channel blockers and thiazide diuretics increased among Black patients after the JNC 8 report encouraged use as first-line therapy, and (3) prescriptions for dual therapy and fixed-dose combination among patients with blood pressure ≥140/90 mm Hg increased after recommendations in the 2017 Hypertension Clinical Practice Guidelines...
April 19, 2024: Journal of the American Heart Association
#10
JOURNAL ARTICLE
Kanako Teramoto, Wan Ting Tay, Jasper Tromp, Wouter Ouwerkerk, Tiew-Hwa Katherine Teng, Chanchal Chandramouli, Oi Wah Liew, Jenny Chong, Katrina K Poppe, Mayanna Lund, Gerry Devlin, Richard W Troughton, Robert N Doughty, Arthur Mark Richards, Carolyn S P Lam
BACKGROUND: The relationship of serial NT-proBNP (N-terminal pro-B-type natriuretic peptide) measurements with changes in cardiac features and outcomes in heart failure (HF) remains incompletely understood. We determined whether common clinical covariates impact these relationships. METHODS AND RESULTS: In 2 nationwide observational populations with HF, the relationship of serial NT-proBNP measurements with serial echocardiographic parameters and outcomes was analyzed, further stratified by HF with reduced versus preserved left ventricular ejection fraction, inpatient versus outpatient enrollment, age, obesity, chronic kidney disease, atrial fibrillation, and attainment of ≥50% guideline-recommended doses of renin-angiotensin system inhibitors and β-blockers...
April 19, 2024: Journal of the American Heart Association
#11
JOURNAL ARTICLE
Leonardo De Luca, Stefania Angela Di Fusco, Gianmarco Iannopollo, Raffaella Mistrulli, Vittoria Rizzello, Alberto Aimo, Alessandro Navazio, Claudio Bilato, Marco Corda, Massimo Di Marco, Giovanna Geraci, Attilio Iacovoni, Massimo Milli, Vittorio Pascale, Carmine Riccio, Pietro Scicchitano, Emanuele Tizzani, Domenico Gabrielli, Massimo Grimaldi, Furio Colivicchi, Fabrizio Oliva
The issue of suboptimal drug regimen adherence in secondary cardiovascular prevention presents a significant barrier to improving patient outcomes. To address this, the utilization of drug combinations, specifically single pill combinations (SPCs) and polypills, was proposed as a strategy to simplify treatment regimens. This approach aims to enhance treatment accessibility, affordability, and adherence, thereby reducing healthcare costs and improving patient health. The document is an ANMCO scientific statement on simplifying drug regimens for secondary cardiovascular prevention...
May 2024: Giornale Italiano di Cardiologia
#12
JOURNAL ARTICLE
Michele Massimo Gulizia, Fabio Maria Turazza, Pietro Ameri, Marco Alings, Ronan Collins, Leonardo De Luca, Marcello Di Nisio, Donata Lucci, Domenico Gabrielli, Stefan Janssens, Iris Parrini, Fausto J Pinto, Jose Luis Zamorano, Furio Colivicchi
BACKGROUND: Cancer is an important condition associated with the development of atrial fibrillation (AF). The objectives of the BLITZ-AF Cancer study were to collect real-life information on the clinical profile and use of antithrombotic drugs in patients with AF and cancer to improve clinical management, as well as the evaluation of the association between different antithrombotic treatments (or their absence) and the main clinical events. METHODS: European multinational, multicenter, prospective, non-interventional study conducted in patients with AF (electrocardiographically confirmed) and cancer occurring within 3 years...
May 2024: Giornale Italiano di Cardiologia
#13
JOURNAL ARTICLE
Raimondo Calvanese, Martina Nesti, Carlo Pignalberi, Pasquale Vergara, Lina Marcantoni, Federico Migliore, Giosuè Mascioli, Raimondo Pittorru, Manuel Antonio Conti, Alessandro Valleggi, Tania Sacco, Francesco Borrello, Amir Kol, Pietro Rossi, Gaetano Thiene, Francesco Zanon
For many years, cardiac pacing has been based on the stimulation of right ventricular common myocardium to correct diseases of the conduction system. The birth and the development of cardiac resynchronization have led to growing interest in the correction and prevention of pacing-induced dyssynchrony. Many observational studies and some randomized clinical trials have shown that conduction system pacing (CSP) can not only prevent pacing-induced dyssynchrony but can also correct proximal conduction system blocks, with reduction of QRS duration and with equal or greater effectiveness than biventricular pacing...
May 2024: Giornale Italiano di Cardiologia
#14
JOURNAL ARTICLE
Furio Colivicchi, Marcello Arca, Stefania Angela Di Fusco, Angela Pirillo, Alberico L Catapano
Over the last decade, several innovative therapeutic options have been developed and marketed for the management of hypercholesterolemia. However, the impossibility of a contextual update of international guidelines and the limits imposed by national regulatory authorities do not allow the use of these treatments in many patients, in particular in those at higher cardiovascular risk. Real-world studies show that the use of lipid-lowering therapies is inadequate even among patients at higher cardiovascular risk, with only 20% achieving recommended low-density lipoprotein cholesterol (LDL-C) levels and the use of combination therapies implemented in only 24% of patients...
May 2024: Giornale Italiano di Cardiologia
#15
JOURNAL ARTICLE
Fabrizio Oliva, Giuseppe Boriani, Paolo Calabrò, Pasquale Caldarola, Stefano Carugo, Battistina Castiglioni, Dario Celentani, Marco Comeglio, Leonardo De Luca, Renata De Maria, Michele Di Muro, Gianfranco Ignone, Filippo Leonardo, Alberto Margonato, Francesco Massari, Adriano Murrone, Federico Nardi, Giuseppe Patti, Gianpiero Perna, Paolo Pinna, Marco Poli, Francesco Prati, Riccardo Raddino, Sante Donato Pierdomenico, Paolo Tammaro, Italo Porto
Ischemia with non-obstructive coronary arteries (INOCA) is defined by the coexistence of anginal symptoms and demonstrable ischemia, with no evidence of obstructive coronary arteries. The underlying mechanism of INOCA is coronary microvascular dysfunction with or without associated vasospasm. INOCA patients have recurrent symptoms, functional limitations, repeated access to the emergency department, impaired quality of life and a higher incidence of cardiovascular events than the general population. Although well described in chronic coronary syndrome guidelines, INOCA remains underdiagnosed in clinical practice because of insufficient awareness, lack of accurate diagnostic tools, and poorly standardized and consistent definitions to diagnose, both invasively and non-invasively, coronary microvascular dysfunction...
May 2024: Giornale Italiano di Cardiologia
#16
JOURNAL ARTICLE
Lawrence Hoang, Bidyut Mani, Gina Wilson, Jenifer Chisom Ogu, Subhash Banerjee, Bala Ramanan, J Gregory Modrall, Carlos H Timaran, Shirling Tsai
OBJECTIVE: Guideline-directed medical therapy (GDMT) for peripheral artery disease (PAD) remains severely underutilized. Prevention of Amputation in Veterans Everywhere (PAVE) is a screening program designed to prevent or delay major lower extremity amputation. The primary objective of this study was to determine if diagnosis of PAD through the PAVE program improves prescription of GDMT in Veterans with asymptomatic PAD. METHODS: Patients enrolled into the PAVE program from our institution from 2020-2021 were included...
April 16, 2024: American Journal of Cardiology
#17
JOURNAL ARTICLE
Jolien W Roos-Hesselink, Chiara Pelosi, Margarita Brida, Julie De Backer, Sabine Ernst, Werner Budts, Helmut Baumgartner, Erwin Oechslin, Daniel Tobler, Adrienne H Kovacs, Giovanni Di Salvo, Jolanda Kluin, Michael A Gatzoulis, Gerhard P Diller
BACKGROUND AND AIM: Congenital heart disease (CHD) is the most common birth defect with prevalence of 0.8%. Thanks to tremendous progress in medical and surgical practice, nowadays, >90% of children survive into adulthood. Recently European Society of Cardiology (ESC), American College of Cardiology (ACC)/ American Heart Association (AHA) issued guidelines which offer diagnostic and therapeutic recommendations for the different defect categories. However, the type of technical exams and their frequency of follow-up may vary largely between clinicians and centres...
April 16, 2024: International Journal of Cardiology
#18
JOURNAL ARTICLE
Juliana Goulart Prata Oliveira Milani, Mauricio Milani, Felipe Vilaça Cavallari Machado, Matthias Wilhelm, Thimo Marcin, Flavio D'Ascenzi, Luna Cavigli, Charly Keytsman, Maarten Falter, Bruno Bonnechere, Raf Meesen, Fabrício Braga, Graziella França Bernardelli Cipriano, Veronique Cornelissen, Kenneth Verboven, Gerson Cipriano Junior, Dominique Hansen
AIMS: To develop and validate equations predicting heart rate (HR) at the first and second ventilatory thresholds (VTs) and an optimized range-adjusted prescription for patients with cardiometabolic disease (CMD). To compare their performance against guideline-based exercise intensity domains. METHODS: Cross-sectional study involving 2,868 CMD patients from nine countries. HR predictive equations for first and second VTs (VT1, VT2) were developed using multivariate linear regression with 975 cycle-ergometer cardiopulmonary exercise tests (CPET)...
April 18, 2024: European Journal of Preventive Cardiology
#19
JOURNAL ARTICLE
Sophia Sgraja, Judith Mollenhauer, Martina Kloepfer, Ute Seeland, Clarissa Kurscheid, Volker Amelung
BACKGROUND: A growing body of evidence has demonstrated that a gender-sensitive approach to healthcare is needed in all areas of medicine. Although medical and nursing guidelines include gender-sensitive care (GSC+) recommendations, the level of implementation in health care practice is unknown. This study aims to examine the current level of implementation and acceptance of GSC+ among physicians and nurses and to identify potential gaps between guidelines and practice and barriers and facilitators of GSC+ implementation, taking the perceptions of all relevant stakeholders into account...
2024: PloS One
#20
JOURNAL ARTICLE
Xuelin Zhang, Grace W K Ho, Yim Wah Mak
BACKGROUND: Chronic heart failure (CHF) poses a significant burden on both patients and their family caregivers (FCs), as it is associated with psychological distress and impaired quality of life (QOL). Acceptance and Commitment Therapy (ACT) supports QOL by focusing on value living and facilitates acceptance of psychological difficulties by cultivating psychological flexibility. A protocol is presented that evaluates the effectiveness of a dyad ACT-based intervention delivered via smartphone on QOL and other related health outcomes compared with CHF education only...
2024: PloS One
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