keyword
MENU ▼
Read by QxMD icon Read
search

Multiple sclerosis AND pain

keyword
https://www.readbyqxmd.com/read/28810314/-clinical-and-pathological-characteristics-of-erdheim-chester-disease-involving-the-lungs
#1
T Lu, S Wang, H Huang, T Wang, M Wang, D R Zhong, R E Feng
Objective: To explore the clinical manifestations, pathological features, differential diagnosis and gene mutation status in patients with pulmonary involvement of Erdheim-Chester disease (ECD). Methods: The clinical data of 4 cases of Erdheim-Chester disease admitted to Peking Union Medical College Hospital from October 2014 to August 2016 were examined for imaging, microscopic and immunohistochemitry findings, and BRAFV600E mutation. The related literatures were reviewed. Results: Among the 4 cases, there were 3 males and 1 female, aging from 7 to 47 years, and the average age was 34...
August 12, 2017: Chinese Journal of Tuberculosis and Respiratory Diseases
https://www.readbyqxmd.com/read/28805566/botulinum-toxin-therapy-for-nonmotor-aspects-of-parkinson-s-disease
#2
Jarosław Sławek, Mariusz Madaliński
The medical treatment of Parkinson's disease (PD) is symptomatic both in terms of motor and nonmotor aspects. The nonmotor symptoms therapy should be taken into account as many of them negatively influence the quality of life and are treatable. Botulinum neurotoxin (BoNT) offers effective treatment for drooling and bladder dysfunctions and alternative treatment for constipation and pain related to parkinsonism. BoNT for drooling is probably the best-documented therapy for nonmotor symptoms by clinical trials...
2017: International Review of Neurobiology
https://www.readbyqxmd.com/read/28793876/patient-satisfaction-with-extavipro%C3%A2-30g-a-new-auto-injector-for-administering-interferon-%C3%AE-1b-in-multiple-sclerosis-results-from-a-real-world-observational-exchange-study
#3
Frank A Hoffmann, Anastasiya Trenova, Miguel A Llaneza, Johannes Fischer, Giacomo Lus, Dorothea von Bredow, Núria Lara, Elaine Lam, Marlies Van Hoef, Rajesh Bakshi
BACKGROUND: Patients with multiple sclerosis (MS) receiving long-term, subcutaneous interferon β-1b (IFN β-1b; Extavia®) often experience injection-site reactions and injection-site pain, which together with other side-effects (such as flu-like symptoms) result in suboptimal treatment compliance/adherence. The EXCHANGE study evaluated patient satisfaction with IFN β-1b treatment, administered using ExtaviPro™ 30G, a new auto-injector, in a real-world setting. METHODS: This 26-week, open-label, prospective, non-interventional, observational, multi-country multi-centre study enrolled patients with MS who had been treated with IFN β-1b or other disease-modifying therapies with a self-administered auto-injector for ≥3 months and who were planned to switch to IFN β-1b treatment administered using ExtaviPro™ 30G as part of routine clinical care...
August 9, 2017: BMC Neurology
https://www.readbyqxmd.com/read/28790539/validation-of-the-disease-specific-questionnaire-msqol-54-in-bosnia-and-herzegovina-multiple-sclerosis-patients-sample
#4
Tarik Catic, Josip Culig, Enra Suljic, Admir Masic, Refet Gojak
INTRODUCTION: The purpose of this study was to validate Bosnian translation of disease specific quality of life measure MSQoL-54 which is widely used in practice. MATERIAL AND METHODS: Previously translated and culturally adopted MSQoL-54 questionnaire used in this study has been provided and licensed by Optum Inc. The questionnaire was validated in 62 MS patients seen at Neurology clinic at University Clinical Center Sarajevo, during April 2016 until May 2016. Internal reliabilities of Bosnian version MSQoL-54 were assessed for multiple item scales by using Cronbach's alpha coefficient...
April 2017: Medical Archives
https://www.readbyqxmd.com/read/28780172/contribution-of-plasma-membrane-calcium-atpases-to-neuronal-maladaptive-responses-focus-on-spinal-nociceptive-mechanisms-and-neurodegeneration
#5
REVIEW
Veronika Khariv, Stella Elkabes
Plasma membrane calcium ATPases (PMCAs) are ion pumps that expel Ca(2+) from cells and maintain Ca(2+) homeostasis. Four isoforms and multiple splice variants play important and non-overlapping roles in cellular function and integrity and have been implicated in diseases including disorders of the central nervous system (CNS). In particular, one of these isoforms, PMCA2, is critical for spinal cord (SC) neuronal function. PMCA2 expression is decreased in SC neurons at onset of symptoms in animal models of multiple sclerosis...
August 2, 2017: Neuroscience Letters
https://www.readbyqxmd.com/read/28770664/hippotherapy-for-patients-with-multiple-sclerosis-a-multicenter-randomized-controlled-trial-ms-hippo
#6
Vanessa Vermöhlen, Petra Schiller, Sabine Schickendantz, Marion Drache, Sabine Hussack, Andreas Gerber-Grote, Dieter Pöhlau
BACKGROUND: Evidence-based complementary treatment options for multiple sclerosis (MS) are limited. OBJECTIVE: To investigate the effect of hippotherapy plus standard care versus standard care alone in MS patients. METHODS: A total of 70 adults with MS were recruited in five German centers and randomly allocated to the intervention group (12 weeks of hippotherapy) or the control group. Primary outcome was the change in the Berg Balance Scale (BBS) after 12 weeks, and further outcome measures included fatigue, pain, quality of life, and spasticity...
August 1, 2017: Multiple Sclerosis: Clinical and Laboratory Research
https://www.readbyqxmd.com/read/28741431/-express-topical-moringin-cream-relieves-neuropathic-pain-by-suppression-of-inflammatory-pathway-and-voltage-gated-ion-channels-in-murine-model-of-multiple-sclerosis
#7
Sabrina Giacoppo, Renato Iori, Placido Bramanti, Emanuela Mazzon
No abstract text is available yet for this article.
January 2017: Molecular Pain
https://www.readbyqxmd.com/read/28729170/how-do-pain-fatigue-depressive-and-cognitive-symptoms-relate-to-well-being-and-social-and-physical-functioning-in-the-daily-lives-of-individuals-with-multiple-sclerosis
#8
Anna L Kratz, Tiffany J Braley, Emily Foxen-Craft, Eric Scott, John Murphy, Susan L Murphy
OBJECTIVE: To examine the relative association between daily change in pain, fatigue, depressed mood, and cognitive function, and four outcomes (positive affect and well-being, ability to participate in social roles and activities, upper extremity (UE) functioning, and lower extremity (LE) functioning). DESIGN: Repeated-measures observational study including a baseline lab visit, followed by seven days of home monitoring that included ecological momentary assessment (EMA) of symptoms (pain, fatigue, depressed mood, and cognitive function) and end-of-day diary surveys of outcomes of interest...
July 17, 2017: Archives of Physical Medicine and Rehabilitation
https://www.readbyqxmd.com/read/28729169/pain-fatigue-and-cognitive-symptoms-are-temporally-associated-within-but-not-across-days-in-multiple-sclerosis
#9
Anna L Kratz, Susan L Murphy, Tiffany J Braley
OBJECTIVE: To examine the temporal associations, within-day and day-to-day, between pain, fatigue, depressed mood, and cognitive function in multiple sclerosis (MS). DESIGN: Repeated-measures study involving seven days of ecological momentary assessment (EMA) of symptoms five times a day. Multilevel mixed models were used to analyze data. SETTING: Community. PARTICIPANTS: Ambulatory adults (N=107) with MS. INTERVENTIONS: Not applicable...
July 17, 2017: Archives of Physical Medicine and Rehabilitation
https://www.readbyqxmd.com/read/28729168/ecological-momentary-assessment-of-pain-fatigue-depressive-and-cognitive-symptoms-reveals-significant-daily-variability-in-multiple-sclerosis
#10
Anna L Kratz, Susan L Murphy, Tiffany J Braley
OBJECTIVE: To describe the daily variability and patterns of pain, fatigue, depressed mood, and cognitive function in persons with multiple sclerosis (MS). DESIGN: Repeated-measures observational study of seven consecutive days of home monitoring, including ecological momentary assessment (EMA) of symptoms. Multilevel mixed models were used to analyze data. SETTING: General community. PARTICIPANTS: Ambulatory adults (N=107) with MS recruited through [Masked] and surrounding community...
July 17, 2017: Archives of Physical Medicine and Rehabilitation
https://www.readbyqxmd.com/read/28725842/understanding-patients-process-to-use-medical-marijuana-a-southern-new-jersey-community-engagement-project
#11
Tara L Crowell
Given the necessity to better understand the process patients need to go through in order to seek treatment via medical marijuana, this study investigates this process to better understand this phenomenon. Specifically, Compassion Care Foundation (CCF) and Stockton University worked together to identify a solution to this problem. Specifically, 240 new patients at CCF were asked to complete a 1-page survey regarding various aspects associated with their experience prior to their use of medicinal marijuana-diagnosis, what prompted them to seek treatment, level of satisfaction with specific stages in the process, total length of time the process took, and patient's level of pain...
September 2016: Journal of patient experience
https://www.readbyqxmd.com/read/28716266/sativex%C3%A2-effects-on-promoter-methylation-and-on-cnr1-cnr2-expression-in-peripheral-blood-mononuclear-cells-of-progressive-multiple-sclerosis-patients
#12
Massimo Santoro, Massimiliano Mirabella, Chiara De Fino, Assunta Bianco, Matteo Lucchini, Francesco Losavio, Andrea Sabino, Viviana Nociti
Multiple sclerosis (MS) is a chronic demyelinating central nervous system (CNS) disease that involve oligodendrocyte loss and failure to remyelinate damaged brain areas causing a progressive neurological disability. Studies in MS mouse model suggest that cannabinoids ameliorate symptoms as spasticity, tremor and pain reducing inflammation via cannabinoid-mediated system. The aim of our study is to investigate the changes in cannabinoid type 1 (CNR1) and 2 (CNR2) receptors mRNA expression levels and promoter methylation in peripheral blood mononuclear cells (PBMCs) of MS secondary progressive (MSS-SP) patients treated with Sativex®...
August 15, 2017: Journal of the Neurological Sciences
https://www.readbyqxmd.com/read/28698092/spasticity-in-multiple-sclerosis-contribution-of-inflammation-autoimmune-mediated-neuronal-damage-and-therapeutic-interventions
#13
REVIEW
Robert Patejdl, Uwe K Zettl
In contrast to other diseases that go along with spasticity (e.g. spinal cord injury), spasticity in chronic autoimmune diseases involving the CNS is complicated by the ongoing damage of neuronal networks that leads to permanent changes in the clinical picture of spasticity. Multiple sclerosis (MS) is the most frequent autoimmune disease of the central nervous system (CNS) and spasticity is one of the most disabling symptoms. It occurs in more than 80% MS patients at some point of the disease and is associated with impaired ambulation, pain and the development of contractures...
July 8, 2017: Autoimmunity Reviews
https://www.readbyqxmd.com/read/28695562/medical-use-of-cannabis-in-switzerland-analysis-of-approved-exceptional-licences
#14
Gablu Kilcher, Marcel Zwahlen, Christopher Ritter, Lukas Fenner, Matthias Egger
AIMS OF THE STUDY: In recent years, the Swiss Federal Office of Public Health (FOPH) granted exceptional licenses for the medical use of cannabinoids, typically for 6 months with possible extensions. A systematic review of cannabinoids for medical use commissioned by the FOPH supports the use of cannabinoids for the treatment of chronic pain and spasticity. However, little is known about the patients treated with cannabinoids. We aimed to study medical uses of cannabinoids as part of the FOPH's programme of exceptional licenses...
July 11, 2017: Swiss Medical Weekly
https://www.readbyqxmd.com/read/28691528/ribbing-disease-a-systematic-review
#15
Bart G Pijls, Koen Steentjes, Jan W Schoones, Sander Pd Dijkstra
Background Ribbing disease, or multiple diaphyseal sclerosis, is a rare benign bone dysplasia. Purpose To systematically review the literature to determine the clinical and radiological presentation of patients with Ribbing disease as well as the effects of attempted treatments. Material and Methods We considered individual patient data of patients diagnosed with Ribbing disease derived from patient reports and patient series. All stages of the review were performed by two reviewers independently. Standard descriptive statistics were used for quantitative analyses and mixed model analyses were used when appropriate Results The literature search yielded 420 unique hits of which 23 studies were included, covering a total of 40 patients of whom 29 had bilateral involvement...
January 1, 2017: Acta Radiologica
https://www.readbyqxmd.com/read/28666966/aapt-diagnostic-criteria-for-central-neuropathic-pain
#16
Eva Widerström-Noga, John D Loeser, Troels Staehelin Jensen, Nanna Brix Finnerup
Central neuropathic pain, which is pain caused by a lesion or disease of the central somatosensory nervous system, is a serious consequence of spinal cord injury, stroke, multiple sclerosis, and other conditions affecting the central nervous system. A collaborative effort between the Analgesic, Anesthetic, and Addiction Clinical Trial Translations, Innovations, Opportunities, and Networks public-private partnership and the American Pain Society, the Analgesic, Anesthetic, and Addiction Clinical Trial Translations, Innovations, Opportunities, and Networks-American Pain Society Pain Taxonomy (AAPT) initiative, invited a working group to develop diagnostic criteria for central neuropathic pain...
June 27, 2017: Journal of Pain: Official Journal of the American Pain Society
https://www.readbyqxmd.com/read/28661948/continuous-in-home-symptom-and-mobility-measures-for-individuals-with-multiple-sclerosis-a-case-presentation
#17
Pamela Newland, Alyssa Kimutis, Amber Salter, Louise Flick, Florian P Thomas, Marilyn Rantz, Marjorie Skubic
Gait impairment represents one of the most common and disabling symptoms of multiple sclerosis (MS). To identify which temporal or spatial parameters of gait could be used as outcome measures in interventional studies of individuals with MS with different levels of disability, we evaluated characteristics of these parameters in a case study of 3 participants with MS, using 1 case as an exemplar and the other participants as validation. A case study of an exemplar participant was conducted with a 67-year-old woman with secondary progressive MS served as exemplar, with 2 other participants (52 and 55 years old) as validation...
August 2017: Journal of Neuroscience Nursing: Journal of the American Association of Neuroscience Nurses
https://www.readbyqxmd.com/read/28661195/optimising-mindfulness-based-stress-reduction-for-people-with-multiple-sclerosis
#18
Robert Simpson, Sharon Byrne, Karen Wood, Frances S Mair, Stewart W Mercer
Objectives To gather views from patients with multiple sclerosis after completing a standard eight-week mindfulness-based stress reduction course and optimise and test a modified version as required. Methods Two successive groups of 25 multiple sclerosis patients received mindfulness-based stress reduction in a wait-list randomised controlled trial. Seventeen participants and two mindfulness-based stress reduction instructors were individually interviewed after the first (standard) course and 16 participants and the same two instructors were interviewed following the second (optimised) course...
January 1, 2017: Chronic Illness
https://www.readbyqxmd.com/read/28655040/factors-associated-with-communicative-participation-in-amyotrophic-lateral-sclerosis
#19
Kathryn Yorkston, Carolyn Baylor, Helen Mach
Purpose: People with amyotrophic lateral sclerosis frequently experience bulbar impairment and dysarthria that may restrict their ability to take part in everyday communication situations. The aim of this study is to examine selected variables that may contribute to restrictions in communicative participation. Method: Community-dwelling participants with amyotrophic lateral sclerosis (N = 70) who reported communication changes but continued to use natural speech completed a survey, including the Communicative Participation Item Bank, demographics (age, sex, living situation, employment status, education, and time since diagnosis), and self- reported symptom-related variables (physical activity, emotional problems, fatigue, pain, speech severity, speech usage, and cognitive and communication skills)...
June 22, 2017: Journal of Speech, Language, and Hearing Research: JSLHR
https://www.readbyqxmd.com/read/28650601/multiple-sclerosis-in-an-acupuncture-practice
#20
(no author information available yet)
Multiple sclerosis (MS) is a severe autoimmune demyelinating disease that affects nervous system, has high morbidity and mortality and no effective targeted therapies are available. We present a case of 66-year-old female patient who has been treated by both conventional and Chinese traditional medicine after diagnosis was confirmed in 2008 as MS and antiphospholipid syndrome associated with CNS vasculitis. After diagnosis with clinical image confirmed with CT and MRI scan, where demyelinating zones were present, she started pharmacological therapy without major improvement...
May 26, 2017: Neuro Endocrinology Letters
keyword
keyword
104613
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"