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Rodolfo Pino, Faro Manzella, Danilo Puccio, Giuseppa Sciortino, Giovanni Polizzi
The pathogenesis of tako-tsubo syndrome remains, nowadays, unclear: it is likely that the relevance of the different proposed mechanisms differs among specific clinical contexts. In this paper, we describe the case of a 61-year-old woman admitted to the intensive cardiac care unit for pre-syncope and persistent hypotension. Clinical and echocardiographic data were suggestive of tako-tsubo syndrome with severe dynamic left ventricular outflow tract (LVOT) obstruction and severe mitral regurgitation. Coronary angiography was normal...
October 2016: Giornale Italiano di Cardiologia
Javier Matabuena Gomez-Limon, Sebastian Isaza Arana, Juan Robledo-Carmona, Edgar Alania Torres, Javier Torres Llergo, Juan Ignacio Valle-Racero, Francisco Lopez Pardo, Angel Martinez-Martinez, Manuel Jimenez-Navarro, Jose Angel Urbano-Moral
OBJECTIVES: To jointly describe clinical characteristics, ECG and echocardiographic findings, and adverse cardiovascular events in patients with tako-tsubo cardiomyopathy (TC) in the long-term. METHODS: Longitudinal multicenter study including retrospective analysis of clinical and ECG data, and follow-up evaluation with clinical interview, electrocardiogram and echocardiogram. RESULTS: Data from 66 cases of TC were available for analysis of clinical and adverse cardiovascular events, and 56 of them completed the follow-up visit including electrocardiogram and echocardiogram...
November 12, 2016: International Journal of Cardiology
Nicolas Mansencal, Olivier Auzel, Olivier Dubourg
No abstract text is available yet for this article.
October 15, 2016: International Journal of Cardiology
Ana Goico, Mercy Chandrasekaran, Cesar J Herrera
Stress cardiomyopathy (SC) is characterized by transient left ventricular (LV) wall motion abnormalities typically involving the apex with preserved basal contractility, chest discomfort, ST-T ischemic changes and elevated cardiac markers with normal or non-flow limiting coronary artery lesions. It represents an important differential diagnosis of Acute Coronary Syndromes caused by atherosclerotic vessel occlusion; most commonly, Tako-tsubo occurs in postmenopausal women after physical or emotional stress. While the exact mechanism of SC remains controversial, various hypotheses have been suggested concerning the vascular, central nervous and endocrine system participation where catecholamines, particularly epinephrine, seem to play a major role...
November 15, 2016: International Journal of Cardiology
Gwenaelle Duhil de Bénazé, Franck Iserin, Philippe Durand, Gudrun Schleiermacher, Daniel Orbach
Acute cardiac dysfunctions associated to neuroblastoma have rarely been reported. Cases already described are mainly related to high blood pressure, and rarely to an "acute catecholamine cardiomyopathy" more frequently found in adults with pheochromocytoma or secreting paraganglioma. We here report a case of an 8-month-old infant with severe acute cardiac failure with dilated cardiomyopathy and moderate ischemic myocardial signs, revealing a favorable histoprognosis neuroblastoma. After specific treatment, evolution was favorable, and cardiac function completely recovered...
October 2016: Journal of Pediatric Hematology/oncology
Laurent Auboire, Joachim Alexandre, Valentina Boccadamo, Cécile Labbé
No abstract text is available yet for this article.
November 15, 2016: International Journal of Cardiology
Andrea Ceccacci, Massimo Mancone, Simone Calcagno, Giuseppe De Vincentis, Gennaro Sardella, Francesco Fedele
No abstract text is available yet for this article.
November 15, 2016: International Journal of Cardiology
José Miguel Hernández Ramírez, Aridane Cárdenes León, Rakesh Gobind Sakhrani
No abstract text is available yet for this article.
August 11, 2016: Revista Española de Cardiología
Adam Lee, Phong Nguyen
We present a case of Tako-tsubo cardiomyopathy (TTC) with regional variation in left ventricular function precipitated by intraocular injection of phenylephrine. To our knowledge, this is the first described case of TTC occurring in the setting of an intraocular medication. Contrary to the traditional model of the β2-receptor underlying the pathophysiology behind Tako-tsubo cardiomyopathy, phenylephrine is a pure α1-agonist implicating alternative mechanisms of myocardial injury resulting in a similar clinical phenotype...
July 19, 2016: Heart, Lung & Circulation
J Oras, B Redfors, E Omerovic, S Ricksten, H Seemann-Lodding
No abstract text is available yet for this article.
December 2015: Intensive Care Medicine Experimental
Kuljit Singh
No abstract text is available yet for this article.
December 2016: European Journal of Heart Failure
Alberto Pérez-Castellanos, Felipe Atienza, Héctor Bueno, Iago Sousa, Francisco Fernández-Avilés
Tako-tsubo cardiomyopathy (TTC) is a syndrome characterized by acute transient ventricular dysfunction in the absence of obstructive coronary artery disease and is predominantly associated with exposure to sudden emotional or physical stress. Patients with TTC may develop serious in-hospital complications, including ventricular arrhythmias. However, triggering of TTC after an electrical storm has not previously been described. We present two cases of TTC induced by multiple shocks in the setting of an electrical storm due to pharmacologically induced long QT syndrome...
April 8, 2016: European Heart Journal. Acute Cardiovascular Care
Pedro Amariles, Laura Cifuentes
BACKGROUND: In 2011 a list of 20 drugs linked to drug-induced Tako-Tsubo cardiomyopathy (TCM) was published. Thus, the objectives were both to identify cases of drug-induced TCM, and update the 2011 list of drugs as possible triggers of this cardiomyopathy. METHOD: As the 2011 report of drug-induced TCM, case reports of drug-induced TCM were identified by a comprehensive search in Medline/PubMed database. From December 2010 to March 2015 search terms were Takotsubo cardiomyopathy, Takotsubo cardiomyopathy, stress cardiomyopathy, transient-left-ventricular ballooning syndrome, ampulla cardiomyopathy, apical ballooning syndrome, OR broken heart syndrome; together with "iatrogenic", "drug-induced", OR "induced by"...
2016: Current Clinical Pharmacology
Luciana Midaglia, Jesús M Juega Mariño, Jaume Sastre-Garriga, Alex Rovira, Angela Vidal-Jordana, María A López-Pérez, María E Marzo-Sola, Fausto Librada Escribano, Xavier Montalban
BACKGROUND: Clinically isolated syndromes affecting the brainstem may present with rare manifestations such as neurogenic pulmonary oedema (NPO). OBJECTIVES: We present the case of a 23 year-old man with NPO caused by Tako-Tsubo cardiomyopathy (TTC) as a first manifestation of multiple sclerosis (MS). METHODS AND RESULTS: A brain magnetic resonance imaging scan at admission showed multiple supra and infratentorial white matter inflammatory demyelinating lesions...
May 2016: Multiple Sclerosis: Clinical and Laboratory Research
Max J Hilz
Autonomic dysfunction is common but frequently overlooked in multiple sclerosis (MS) patients. The case of a Tako-Tsubo cardiomyopathy on which this commentary is based shows that centrally triggered autonomic dysfunction may be the first life-threatening manifestation of MS.
May 2016: Multiple Sclerosis: Clinical and Laboratory Research
Dong-Mei Jiang, Ze-Wei Sunc, Jie Han
OBJECTIVE: To report a case of Tako-tsubo cardiomyopathy in a blind woman. CASE PRESENTATION: We report a confirmed case of Tako-tsubo cardiomyopathy in a 55-year-old blind woman with past medical history of ocular trauma. The patient suffered from sudden chest pain after a quarrel. Transthoracic echocardiogram (TTE) showed regional wall motion abnormalities. Coronary angiogram showed no significant coronary stenosis, but ventriculogram demonstrated apical ballooning akinesis and hypercontraction in the basal segments...
December 2015: African Health Sciences
Fabrizio Ugo, Mario Iannaccone, Fabrizio D'Ascenzo, Flavia Ballocca, Nicola Gaibazzi, Filippo Cademartiri, Annachiara Aldrovandi, Diego Ardissino, Claudio Moretti, Fiorenzo Gaita
No abstract text is available yet for this article.
April 15, 2016: International Journal of Cardiology
Nicole Maison, Esther Korpershoek, Graeme Eisenhofer, Mercedes Robledo, Ronald de Krijger, Felix Beuschlein
UNLABELLED: Pheochromocytomas (PCC) and paraganglioma (PGL) are rare neuroendocrine tumors arising from chromaffin cells of the neural crest. Mutations in the RET-proto-oncogene are associated with sporadic pheochromocytoma, familial or sporadic medullary thyroid carcinoma (MTC) and multiple endocrine neoplasia type 2. In the past, only few cases of pigmented PCCs, PGLs, and one case of pigmented MTC have been reported in the literature. Herein, we present the case of a 77-year old woman with a history of Tako-tsubo-cardiomyopathy and laboratory, as well as radiological, high suspicion of pheochromocytoma, who underwent left-sided adrenalectomy...
2016: Endocrinology, Diabetes & Metabolism Case Reports
Giulia Brunelli, Simonetta Tesoro, Andrea Trotta, Nadia Dentini, Vito A Peduto
No abstract text is available yet for this article.
April 2016: Minerva Anestesiologica
Caroline Scally, Trevor Ahearn, Amelia Rudd, Christopher J Neil, Janaki Srivanasan, Baljit Jagpal, John Horowitz, Michael Frenneaux, Dana K Dawson
Acute stress-induced (Tako-tsubo) cardiomyopathy is an increasingly recognized but insufficiently characterized syndrome. Here, we investigate the pathophysiology of right ventricular (RV) involvement in Tako-tsubo and its recovery time course. We prospectively recruited 31 patients with Tako-tsubo with predominantly ST-elevation electrocardiogram and 18 controls of similar gender, age, and co-morbidity distribution. Patients underwent echocardiography and cardiac magnetic resonance (CMR) imaging on a 3T Philips scanner in the acute phase (day 0 to 3 after presentation) and at 4-months follow-up...
March 1, 2016: American Journal of Cardiology
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