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Eric J Cotter, Charles P Hannon, David Christian, Rachel M Frank, Bernard R Bach
CONTEXT: Shoulder pain and dysfunction are common, with patients presenting complaints to both primary and orthopaedic physicians. History and physical examination remain essential to creating a differential diagnosis, even as noninvasive imaging has improved. EVIDENCE ACQUISITION: Literature was obtained through keyword searches based on the pathology in question (eg, rotator cuff) and the keywords physical examination using PubMed from January 1, 1980, through September 20, 2017...
February 1, 2018: Sports Health
Gemma Mestre-Bach, Trevor Steward, Roser Granero, Fernando Fernández-Aranda, María Teresa Talón-Navarro, Àngel Cuquerella, Marta Baño, Laura Moragas, Amparo Del Pino-Gutiérrez, Neus Aymamí, Mónica Gómez-Peña, Núria Mallorquí-Bagué, Cristina Vintró-Alcaraz, Pablo Magaña, José Manuel Menchón, Susana Jiménez-Murcia
Gambling disorder (GD) is a psychiatric condition that was recently recategorized as a non-substance-related addiction in the Diagnostic and Statistical Manual of Mental Health Disorders. Criminal activity is commonly associated with gambling; however, few empirical studies to date have examined sociodemographic and psychological variables in this population. In this study, we explored criminal behavior history in a sample of consecutively recruited treatment-seeking gamblers (n = 382) and compared subjects with a history of illegal acts (n = 103, 26...
2018: Frontiers in Psychiatry
Lennart T Bach, Kai T Lohbeck, Thorsten B H Reusch, Ulf Riebesell
Climate change challenges plankton communities, but evolutionary adaptation could mitigate the potential impacts. Here, we tested with the phytoplankton species Emiliania huxleyi whether adaptation to a stressor under laboratory conditions leads to equivalent fitness gains in a more natural environment. We found that fitness advantages that had evolved under laboratory conditions were masked by pleiotropic effects in natural plankton communities. Moreover, new genotypes with highly variable competitive abilities evolved on timescales significantly shorter than climate change...
February 12, 2018: Nature Ecology & Evolution
Kyun Ha Kim, Eun Jung Kim, Min Jung Kwun, Ji Yeon Lee, Tran The Bach, Sang Mi Eum, Jun Yong Choi, Sayeon Cho, Sang-Jun Kim, Seung-Il Jeong, Myungsoo Joo
ETHNOPHARMACOLOGICAL RELEVANCE: Although Spilanthes acmella has been used to relieve inflammation, fever, pain, or infection in traditional Asian medicine, experimental evidence supporting these functions is scarce. Here, we examined an anti-inflammatory function and a possible underlying mechanism of S. acmella Murray (SAM). MATERIALS AND METHOD: The methanol extract of SAM was fingerprinted by HPLC. C57BL/6 mice were administered with a single intratracheal (i...
February 9, 2018: Journal of Ethnopharmacology
Maria Bach Okholm-Hansen, Anna Hillert Winther, Christina Fagerberg, Marianne Antonius Jakobsen, Anette Bygum
Hereditary angio-oedema (HAE) is a rare, potentially fatal disease characterized by recurrent swelling of skin and mucosa. Besides HAE with quantitative (type I) or qualitative (type II) deficiency of complement C1-inhibitor (C1-INH), a new subtype of HAE is now described with normal levels of C1-INH. This subtype is possibly underdiagnosed, and a treatment regimen and general knowledge about the condition is still in its infancy. The purpose of this article is to inform Danish doctors about the disease to identify more Danish patients...
February 5, 2018: Ugeskrift for Laeger
Ádám Bach, Balázs Sztanó, József Géza Kiss, Gerd Fabian Volk, Andreas Müller, Claus Pototschnig, László Rovó
The development of the therapeutic possibilities of vocal cord immobility necessitated the parallel renewal of diagnostic methods. In the last years, laryngeal electromyography, which was first introduced more than 70 years ago, has been re-discovered. After reviewing the international literature and their own experience, the authors present the indications, technical requirements, method and, particularly, the evaluation of the results of this procedure. Laryngeal electromyography makes the differentiation between mechanical fixation and immobility with neurological origin of the vocal folds possible...
February 2018: Orvosi Hetilap
Jinpeng Li, Anthony Bach, Robert B Crawford, Ashwini S Phadnis-Moghe, Weimin Chen, Shawna D'Ingillo, Natalia Kovalova, Jose E Suarez-Martinez, Jiajun Zhou, Barbara L F Kaplan, Norbert E Kaminski
Bisphenol A (BPA) is extensively used in manufacturing of a broad range of consumer products worldwide. Due to its widespread use, human exposure to BPA is virtually ubiquitous. Broad human exposure coupled with a large scientific literature describing estrogenic activity of BPA in animals has raised public health concerns. To comprehensively evaluate the health effects of BPA exposure, a chronic toxicity study using a wide-range of BPA doses (2.5-25000 μg/kg bw/day) was conducted jointly by the NTP, thirteen NIEHS-supported grantees, and the FDA, which is called the Consortium Linking Academic and Regulatory Insights on Toxicity of BPA (CLARITY-BPA)...
February 8, 2018: Toxicology
Jinpeng Li, Anthony Bach, Robert B Crawford, Ashwini S Phadnis-Moghe, Weimin Chen, Shawna D'Ingillo, Natalia Kovalova, Jose E Suarez-Martinez, Jiajun Zhou, Barbara L F Kaplan, Norbert E Kaminski
Bisphenol A (BPA) is commonly used in the manufacturing of a wide range of consumer products, including polycarbonate plastics, epoxy resin that lines beverage and food cans, and some dental sealants. Consumption of food and beverages containing BPA represents the primary route of human BPA exposure, which is virtually ubiquitous. An increasing number of studies have evaluated the effects of BPA on immune responses in laboratory animals that have reported a variety of effects some of which have been contradictory...
February 7, 2018: Toxicology
Johannes Cip, Florian Obwegeser, Thomas Benesch, Christian Bach, Paul Ruckenstuhl, Arno Martin
BACKGROUND: Navigated computer-assisted total knee arthroplasty (TKA) was introduced to expedite long-term survival based on improved postoperative implantation accuracy. However, long-term outcome data after 10 years or more are rare, even available meta-analyses show controversial study results. METHODS: In a prospective randomized trial, 100 conventional TKAs (group CONV) were compared with 100 computer-assisted TKAs (group NAV) after a mean follow-up of 12 years postoperatively...
December 21, 2017: Journal of Arthroplasty
Bérengère Laporte, Jérôme Gay-Quéheillard, Véronique Bach, Anne-Sophie Villégier
Today, developmental intellectual disorders affect one out of six children in industrialised countries. Intensively used in agriculture, the neurotoxicant pesticide chlorpyrifos (CPF) is known for its environmental persistence and bioaccumulation. Its role has not yet been established in the aetiology of intellectual impairments. Here we assessed whether maternal ingestion of low CPF dose in rats could impair the cerebral function of their progeny. Rat dams received daily CPF exposures (1 mg/kg, per os) during gestation and lactation...
January 25, 2018: Food and Chemical Toxicology
Kasper Glerup Lauridsen, Anders Sjørslev Schmidt, Kasper Adelborg, Leif Bach, Nete Hornung, Simon Munkesø Jepsen, Charles D Deakin, Hans Rickers, Bo Løfgren
Oxygen has long been assumed beneficial for all ill and injured patients. However, hyperoxia may be harmful and aggravate myocardial injury such as that caused by myocardial infarction. We aimed to investigate if hyperoxia increases myocardial injury following direct current cardioversion compared with room air. METHODS: Patients undergoing elective biphasic cardioversion for atrial fibrillation or atrial flutter were randomized to receive room air or oxygen (10-15 L/min) during the procedure...
February 2018: American Heart Journal
Duc-Hiep Bach, Sang Kook Lee
Long noncoding RNA (lncRNA) has recently been investigated as key modulators that regulate many biological processes in human cancers via diverse mechanisms. LncRNAs can interact with macromolecules such as DNA, RNA, or protein to exert cellular effects and to act as either tumor promoters or tumor suppressors in various malignancies. Moreover, the aberrant expression of lncRNAs may be detected in multiple cancer phenotypes by employing the rapidly developing modern gene chip technology and bioinformatics analysis...
January 27, 2018: Cancer Letters
Constantin Tuleasca, Jean Régis, Elena Najdenovska, Tatiana Witjas, Nadine Girard, Jérôme Champoudry, Mohamed Faouzi, Jean-Philippe Thiran, Meritxell Bach Cuadra, Marc Levivier, Dimitri Van De Ville
OBJECTIVE: To correlate pretherapeutic resting-state functional MRI (rs-fMRI) measures with pretherapeutic head tremor presence and/or further improvement 1 year after stereotactic radiosurgical thalamotomy (SRS-T) for essential tremor (ET). METHODS: We prospectively collected head tremor scores (range 0-3) and rs-fMRI data for a cohort of 17 consecutive ET patients in pretherapeutic and 1 year after SRS-T states. We additionally acquired rs-fMRI data for a healthy control (HC) group (n=12)...
January 31, 2018: World Neurosurgery
Andrea Hettmann, Anett Demcsák, Ádám Bach, Gábor Decsi, Ágnes Dencs, Dóra Pálinkó, László Rovó, Gabriella Terhes, Edit Urbán, Krisztina Buzás, Katalin Nagy, Mária Takács, Janos Minarovits
In addition to traditional risk factors such as smoking, alcohol consumption and betel nut use, human papillomavirus (HPV) infection also plays a role in the development of head and neck squamous cell carcinomas (HNSCCs). Although among European countries the highest incidence and mortality rates of head and neck cancer types were recorded in Hungary, data regarding HPV prevalence in HNSCCs is scarce. We collected biopsy and saliva samples from patients diagnosed with HNSCC or oral potentially malignant disorders (OPMDs) and tested them for the presence of HPV using the PCR consensus primer set MY09/11 and the GP5+/6+ primer pair...
January 31, 2018: Infection, Genetics and Evolution
Gemma Mestre-Bach, Trevor Steward, Roser Granero, Fernando Fernández-Aranda, María Teresa Talón-Navarro, Àngel Cuquerella, Amparo Del Pino-Gutiérrez, Neus Aymamí, Mónica Gómez-Peña, Núria Mallorquí-Bagué, Teresa Mena-Moreno, Cristina Vintró-Alcaraz, Marta Baño, Laura Moragas, Pablo Magaña, José Manuel Menchón, Susana Jiménez-Murcia
INTRODUCTION: Women have been underrepresented in the empirical research of gambling disorder (GD), a psychiatric condition included in the Diagnostic and Statistical Manual of Mental Health Disorders (DSM-5). More specifically, no studies to date have been carried out exploring the clinical phenotype of women with GD who have committed gambling-related illegal acts. AIMS: In this study, we sought to delineate the clinical, personality and psychopathological differences between treatment-seeking women with GD, with and without a criminal record...
January 24, 2018: Addictive Behaviors
Nancy Reau, Michael N Robertson, Hwa-Ping Feng, Luzelena Caro, Wendy W Yeh, Bach-Yen T Nguyen, Janice Wahl, Eliav Barr, Peggy Hwang, Stephanie O Klopfer
Concomitant proton pump inhibitor (PPI) use reduces plasma concentrations of certain nonstructural protein 5A inhibitors, which are key components of modern hepatitis C infection (HCV) treatments. These reduced concentrations may decrease efficacy, leading to challenging treatment failures due to the development of resistance-associated substitutions. This post-hoc analysis assessed 12-week sustained viral response (SVR12) and pharmacokinetics of fixed-dose combination elbasvir/grazoprevir (EBR/GZR) in patients with HCV infection and self-reported PPI use...
October 2017: Hepatology Communications
Dennis Mackin, Rachel Ger, Cristina Dodge, Xenia Fave, Pai-Chun Chi, Lifei Zhang, Jinzhong Yang, Steve Bache, Charles Dodge, A Kyle Jones, Laurence Court
Variability in the x-ray tube current used in computed tomography may affect quantitative features extracted from the images. To investigate these effects, we scanned the Credence Cartridge Radiomics phantom 12 times, varying the tube current from 25 to 300 mA∙s while keeping the other acquisition parameters constant. For each of the scans, we extracted 48 radiomic features from the categories of intensity histogram (n = 10), gray-level run length matrix (n = 11), gray-level co-occurrence matrix (n = 22), and neighborhood gray tone difference matrix (n = 5)...
February 5, 2018: Scientific Reports
Lionel Chok, Esther B Bachli, Peter Steiger, Dominique Bettex, Silvia R Cottini, Emanuela Keller, Marco Maggiorini, Reto A Schuepbach
BACKGROUND: In 2013 the Swiss Diagnosis Related Groups ((Swiss)-DRG) was implemented in Intensive Care Units (ICU). Its impact on hospitalizations has not yet been examined. We compared the number of ICU admissions, according to clinical severity and referring institution, and screened whether implementation of Swiss-DRG affected admission policy, ICU length-of-stay (ICU-LOS) or ICU mortality. METHODS: Retrospective, single centre, cohort study conducted at the University Hospital Zurich, Switzerland between January 2009 and end of September 2013...
February 5, 2018: BMC Health Services Research
Alexander E Weber, William Zuke, Erik N Mayer, Brian Forsythe, Alan Getgood, Nikhil N Verma, Bernard R Bach, Asheesh Bedi, Brian J Cole
BACKGROUND: There has been an increasing interest in lateral-based soft tissue reconstructive techniques as augments to anterior cruciate ligament reconstruction (ACLR). The objective of these procedures is to minimize anterolateral rotational instability of the knee after surgery. Despite the relatively rapid increase in surgical application of these techniques, many clinical questions remain. PURPOSE: To provide a comprehensive update on the current state of these lateral-based augmentation procedures by reviewing the origins of the surgical techniques, the biomechanical data to support their use, and the clinical results to date...
February 1, 2018: American Journal of Sports Medicine
Abbas Agaimy, Evgeny A Moskalev, Wera Weisser, Thorsten Bach, Florian Haller, Arndt Hartmann
Tumors with Müllerian-like serous or mucinous phenotypes originating in the testis and its adnexa are rare neoplasms that have been increasingly recognized in recent years. Cystadenomas with or without ovarian-type stroma, borderline tumors, and adenocarcinomas are the main documented types. Although a handful cases of putative endometrioid adenocarcinomas have been reported, to our knowledge no case of endometrial stromal-type neoplasm has ever been reported in the literature. A 59-year-old man presented with a 2 cm left intrascrotal mass that was found on sonographic examination to arise from the epididymal tail with prominent vascularization...
February 1, 2018: American Journal of Surgical Pathology
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