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https://www.readbyqxmd.com/read/28214173/pyrocarbon-interposition-shoulder-arthroplasty-preliminary-results-from-a-prospective-multicenter-study-at-2-years-of-follow-up
#1
Jérôme Garret, Arnaud Godeneche, Pascal Boileau, Daniel Molé, Mikael Etzner, Luc Favard, Christophe Levigne, François Sirveaux, Marc-Olivier Gauci, Charles Dezaly, Gilles Walch
BACKGROUND: The concept of free interposition arthroplasty proved successful for small joints of the hand, wrist, and foot, particularly after the use of implants coated with pyrocarbon, which enhanced their tribologic and elastic properties. The present study reports preliminary outcomes of a pyrocarbon-coated interposition shoulder arthroplasty (PISA) implant. METHODS: This was a prospective study of 67 consecutive patients who underwent shoulder PISA at 9 centers...
February 14, 2017: Journal of Shoulder and Elbow Surgery
https://www.readbyqxmd.com/read/28213799/the-hybrid-technique-of-pelvic-organ-prolapse-treatment-apical-sling-and-subfascial-colporrhaphy
#2
Dmitry Shkarupa, Nikita Kubin, Alexey Pisarev, Anastasiya Zaytseva, Ekaterina Shapovalova
INTRODUCTION AND HYPOTHESIS: The majority of patients with cystocele undergoing reconstructive surgery have combined defects of pubocervical fascia and uterosacral/cardinal ligament complex. In this regard, the simultaneous correction of both defects is rational. Furthermore, decreasing the use of synthetic materials in pelvic floor surgery is an important goal. The aim was to evaluate the objective and subjective cure rate of a hybrid technique: bilateral sacrospinous fixation using modern monofilament synthetic tape (apical sling) combined with the original technique of subfascial colporrhaphy...
February 17, 2017: International Urogynecology Journal
https://www.readbyqxmd.com/read/28213280/magnetic-lateral-flow-immunoassay-test-strip-development-considerations-for-proof-of-concept-evaluation
#3
R Connolly, R O' Kennedy
Lateral flow immunoassays (LFIA) have grown to become the predominant test device format for the diagnostics and point-of-care industries. The demand for robust and reproducible LFIAs has been facilitated through scale-up production methods using specialized and automated instruments. However, the feasibility of a LFIA device can still be evaluated in a small-scale laboratory setting through controlled manual preparation methods. The advent of super-paramagnetic (SPMP) labels for use in lateral flow has heralded the possibility of highly sensitive and stable LFIAs...
February 14, 2017: Methods: a Companion to Methods in Enzymology
https://www.readbyqxmd.com/read/28213250/novel-electroanalytical-method-based-on-the-electrostriction-phenomenon-and-its-application-to-determination-of-cr-vi-by-the-flow-injection-technique
#4
Marcin Wieczorek, Jolanta Kochana, Paweł Knihnicki, Karolina Wapiennik, Paweł Kościelniak
The electrostriction phenomenon is observed in membranes of thickness in the nanometer range, e.g. bilayer lipid membranes or self-assembled monolayers. Strong electrical field of 105-106V/cm in intensity appears when applying the potential lower than 1V to these membranes. Electrostatic forces change the dimensions of a dielectric, hence the membrane compression and decrease in thickness are observed. As a result, increase in the membrane capacitance is recorded. The presented work covers development and application of a new analytical method based on the innovative capacitance-to-frequency conversion method and flow technique...
May 1, 2017: Talanta
https://www.readbyqxmd.com/read/28213156/myotonic-dystrophy-disease-repeat-range-penetrance-age-of-onset-and-relationship-between-repeat-size-and-phenotypes
#5
REVIEW
Kevin Yum, Eric T Wang, Auinash Kalsotra
Myotonic dystrophy (DM) is an autosomal dominant neuromuscular disease primarily characterized by myotonia and progressive muscle weakness. The pathogenesis of DM involves microsatellite expansions in noncoding regions of transcripts that result in toxic RNA gain-of-function. Each successive generation of DM families carries larger repeat expansions, leading to an earlier age of onset with increasing disease severity. At present, diagnosis of DM is challenging and requires special genetic testing to account for somatic mosaicism and meiotic instability...
February 14, 2017: Current Opinion in Genetics & Development
https://www.readbyqxmd.com/read/28212348/an-electromagnetic-sensor-for-the-autonomous-running-of-visually-impaired-and-blind-athletes-part-ii-the-wearable-device
#6
Marco Pieralisi, Valentina Di Mattia, Valerio Petrini, Alfredo De Leo, Giovanni Manfredi, Paola Russo, Lorenzo Scalise, Graziano Cerri
Currently, the availability of technology developed to increase the autonomy of visually impaired athletes during sports is limited. The research proposed in this paper (Part I and Part II) focuses on the realization of an electromagnetic system that can guide a blind runner along a race track without the need for a sighted guide. In general, the system is composed of a transmitting unit (widely described in Part I) and a receiving unit, whose components and main features are described in this paper. Special attention is paid to the definition of an electromagnetic model able to faithfully represent the physical mechanisms of interaction between the two units, as well as between the receiving magnetic sensor and the body of the user wearing the device...
February 16, 2017: Sensors
https://www.readbyqxmd.com/read/28211823/symptom-severity-and-life-satisfaction-in-brain-injury-the-mediating-role-of-disability-acceptance-and-social-self-efficacy
#7
Nicole Ditchman, Connie Sung, Amanda B Easton, Kristina S Johnson, Elisabeth Batchos
BACKGROUND: Although the negative impact of symptom severity on subjective well-being outcomes has been established among individuals with brain injury, the mediating and protective role that positive human traits might have on this relationship has not been adequately explored. OBJECTIVE: The purpose of this study was to examine the impact of social self-efficacy and disability acceptance on the relationship between symptom severity and life satisfaction among individuals with brain injury...
February 15, 2017: NeuroRehabilitation
https://www.readbyqxmd.com/read/28211487/natural-persistence-of-the-coastal-plant-glehnia-littoralis-along-temperate-sandy-coasts
#8
Hong-Xiao Yang, Jian-Min Chu, Xiao-Shan Liu
We studied germination behaviors and persistence mechanism of wild Glehnia littoralis, a typical coastal species at temperate sandy coasts of the North Pacific Ocean, and tested the hypothesis that the coastal plants may have evolved special seeds adapting to the coasts, by which they recruit and persist easily, occupying the coasts as ideal habitats. In the Shandong Peninsula, China, we investigated temperature and moisture conditions of coast sand in relation to germination and evaluated effects of sand burial, seawater immersion and sowing time on germination...
February 17, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28211157/unravelling-intravertebral-integration-modularity-and-disparity-in-felidae-mammalia
#9
Marcela Randau, Anjali Goswami
Morphological integration and modularity, which describe the relationships among morphological attributes and reflect genetic, developmental, and functional interactions, have been hypothesized to be major influences on trait responses to selection and thus morphological evolution. The mammalian presacral vertebral column shows little variation in vertebral count and therefore specialization for function occurs primarily through modification of vertebral shape. However, vertebral shape has been suggested to be under strong control from developmental canalization, although this has never been explicitly tested...
February 17, 2017: Evolution & Development
https://www.readbyqxmd.com/read/28210835/a-10-year-review-of-cannabis-exposure-in-children-under-3-years-of-age-do-we-need-a-more-global-approach
#10
Isabelle Claudet, Mathilde Le Breton, Camille Bréhin, Nicolas Franchitto
: Pediatricians working in an emergency environment are confronted with children admitted to emergency departments for intoxication on a daily basis. We carried out a retrospective cohort study of children admitted to a pediatric emergency department due to unintentional cannabis exposure over a 10-year period from 2004 to 2014. Twenty-nine children under the age of 3 were admitted with a positive cannabis urine test. Eighty-seven percent of intoxications occurred at the family home. Resin was the main form of ingested cannabis (69%)...
February 16, 2017: European Journal of Pediatrics
https://www.readbyqxmd.com/read/28210823/non-ablative-erbium-yag-laser-for-the-treatment-of-type-iii-stress-urinary-incontinence-intrinsic-sphincter-deficiency
#11
Adrian Gaspar, Hugo Brandi
The objective of this pilot study was to determine the safety and efficacy of a new non-ablative erbium YAG laser procedure for the treatment of type III stress urinary incontinence (intrinsic sphincter deficiency) in women. Twenty-two patients with a Valsalva leak point pressure less than 60 cm H2O were recruited and treated with a non-ablative erbium laser delivering low fluence pulses inside the whole length of the urethra through a specially designed cannula. Treatment consisted of two treatment sessions with a 3-week interval in-between...
February 16, 2017: Lasers in Medical Science
https://www.readbyqxmd.com/read/28208845/role-of-altered-venous-blood-lactate-and-hba1c-in-women-with-gestational-diabetes-mellitus
#12
C S Nagalakshmi, N U Santhosh, N Krishnamurthy, Chethana Chethan, M K Shilpashree
INTRODUCTION: Being a mirror image of metabolic syndrome, Gestational Diabetes Mellitus (GDM) is associated with significant maternal and fetal morbidity. Increased blood lactate concentration and alterations of substrate utilization are partly involved in development of insulin resistance in GDM. Fetuses born to such mothers have shown low umbilical vein oxygen saturation and low oxygen content and increased lactate concentrations. These changes may certainly reflect enhanced fetal metabolism as a result of hyperglycaemia and hyperinsulinemia and therefore, these fetuses deserve intense surveillance at term and during delivery...
December 2016: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/28207815/generalist-dispersers-promote-germination-of-an-alien-fleshy-fruited-tree-invading-natural-grasslands
#13
Martín Raúl Amodeo, María Belén Vázquez, Sergio Martín Zalba
Plants with animal-dispersed fruits seem to overcome the barriers that limit their spread into new habitats more easily than other invasive plants and, at the same time, they pose special difficulties for containment, control or eradication. The effects of animals on plant propagules can be very diverse, with positive, neutral or negative consequences for germination and recruitment. Moreover, the environmental conditions where the seeds are deposited and where the post-dispersal processes take place can be crucial for their fate...
2017: PloS One
https://www.readbyqxmd.com/read/28207390/fast-and-accurate-rat-head-motion-tracking-with-point-sources-for-awake-brain-pet
#14
Alan Miranda, Steven Staelens, Sigrid Stroobants, Jeroen Verhaeghe
To avoid the confounding effects of anesthesia and immobilization stress in rat brain positron emission tomography (PET), motion tracking based unrestrained awake rat brain imaging is being developed. In this work we propose a fast and accurate rat head motion tracking method based on small PET point sources. PET point sources (3-4) attached to the rat's head are tracked in image space using 15-32 ms time frames. Our point source tracking (PST) method was validated using a manually moved microDerenzo phantom that was simultaneously tracked with an optical tracker (OT) for comparison...
February 13, 2017: IEEE Transactions on Medical Imaging
https://www.readbyqxmd.com/read/28206667/geometry-calibration-method-for-a-cone-beam-ct-system
#15
Hongkai Yang, Kejun Kang, Yuxiang Xing
PURPOSE: The positioning accuracy of each component is important to ensure the image quality of cone-beam CT. However, accurate positioning is not easy and requires experience and time. The option is to calibrate the geometric parameters and then plug them into a reconstruction algorithm which is the preferred solution in practice. In this case, the image quality is determined by the accuracy and precision of the calibration method. This work describes a method to independently calibrate an imaging system in each pose (projection angle) for a cone-beam CT with a non-ideal-circular trajectory...
February 16, 2017: Medical Physics
https://www.readbyqxmd.com/read/28205468/vascularized-medial-femoral-condyle-bone-graft-for-resistant-nonunion-of-the-distal-radius
#16
Mark Henry
BACKGROUND: Nonunion involving the metaphyseal region of the distal radius is exceedingly rare, usually involving co-morbidity. Patients that have failed multiple prior conventional surgical interventions represent an even more difficult subset to treat; this investigation examined the utility of a specially designed free vascularized medial femoral condyle flap consisting of a central structural block graft with an extended corticoperiosteal sleeve to wrap around the junctions. METHODS: Six patients (5 males, 1 female) with a mean age of 52 years had failed to achieve union involving the distal radius metaphysis after a mean of 3...
March 2017: Journal of Hand Surgery Asian-Pacific Volume
https://www.readbyqxmd.com/read/28203736/identification-of-kiaa1210-as-a-novel-x-chromosome-linked-protein-that-localizes-to-the-acrosome-and-associates-with-the-ectoplasmic-specialization-in-testes
#17
Tokuko Iwamori, Naoki Iwamori, Masaki Matsumoto, Etsuro Ono, Martin M Matzuk
No abstract text is available yet for this article.
February 1, 2017: Biology of Reproduction
https://www.readbyqxmd.com/read/28202813/female-fecundity-variation-affects-reproducibility-of-experiments-on-host-plant-preference-and-acceptance-in-a-phytophagous-insect
#18
Alexander Schäpers, Hampus Petrén, Christopher W Wheat, Christer Wiklund, Magne Friberg
Reproducibility is a scientific cornerstone. Many recent studies, however, describe a reproducibility crisis and call for assessments of reproducibility across scientific domains. Here, we explore the reproducibility of a classic ecological experiment-that of assessing female host plant preference and acceptance in phytophagous insects, a group in which host specialization is a key driver of diversification. We exposed multiple cohorts of Pieris napi butterflies from the same population to traditional host acceptance and preference tests on three Brassicaceae host species...
February 22, 2017: Proceedings. Biological Sciences
https://www.readbyqxmd.com/read/28202740/health-equity-considerations-for-developing-and-reporting-patient-reported-outcomes-in-clinical-trials-a-report-from-the-omeract-equity-special-interest-group
#19
Jennifer Petkovic, Jennifer L Barton, Caroline Flurey, Niti Goel, Christie M Bartels, Cheryl Barnabe, Maarten P T de Wit, Anne Lyddiatt, Diane Lacaille, Vivian Welch, Annelies Boonen, Beverley Shea, Robin Christensen, Lara J Maxwell, Willemina Campbell, Janet Jull, Karine Toupin-April, Jasvinder A Singh, Charles H Goldsmith, Antoine G Sreih, Christoph Pohl, Catherine Hofstetter, Dorcas E Beaton, Rachelle Buchbinder, Francis Guillemin, Peter S Tugwell
OBJECTIVE: Despite advances integrating patient-centered outcomes into rheumatologic studies, concerns remain regarding their representativeness across diverse patient groups and how this affects equity. The Outcome Measures in Rheumatology (OMERACT) Equity Working Group aims to determine whether and how to address equity issues within the core outcome sets of domains and instruments. METHODS: We surveyed current and previous OMERACT meeting attendees and members of the Campbell and Cochrane Equity Group regarding whether to address equity issues within the OMERACT Filter 2...
February 15, 2017: Journal of Rheumatology
https://www.readbyqxmd.com/read/28202729/synchronous-spikes-are-necessary-but-not-sufficient-for-a-synchrony-code-in-populations-of-spiking-neurons
#20
Jan Grewe, Alexandra Kruscha, Benjamin Lindner, Jan Benda
Synchronous activity in populations of neurons potentially encodes special stimulus features. Selective readout of either synchronous or asynchronous activity allows formation of two streams of information processing. Theoretical work predicts that such a synchrony code is a fundamental feature of populations of spiking neurons if they operate in specific noise and stimulus regimes. Here we experimentally test the theoretical predictions by quantifying and comparing neuronal response properties in tuberous and ampullary electroreceptor afferents of the weakly electric fish Apteronotus leptorhynchus These related systems show similar levels of synchronous activity, but only in the more irregularly firing tuberous afferents a synchrony code is established, whereas in the more regularly firing ampullary afferents it is not...
February 15, 2017: Proceedings of the National Academy of Sciences of the United States of America
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