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https://www.readbyqxmd.com/read/28955479/granulomatous-colitis-more-than-a-canine-disease-a-case-of-escherichia-coli-associated-granulomatous-colitis-in-an-adult-cat
#1
Rodolfo Oliveira Leal, Kenny Simpson, Mélanie Fine, Jean-Charles Husson, Juan Hernandez
CASE SUMMARY: This report describes a 4-year-old cat with chronic intermittent haematochezia and faecal incontinence of 7 months' duration. Investigation revealed severe colonic multifocal mucosal ulcerations and infiltration of the mucosal lamina propria by large numbers of periodic acid-Schiff-positive macrophages. Fluorescence in situ hybridisation analysis of colonic biopsies revealed multifocal clusters of intracellular Escherichia coli. Treatment with fluoroquinolones for 6 weeks led to a complete resolution of clinical signs...
July 2017: JFMS open reports
https://www.readbyqxmd.com/read/28954745/spontaneous-intramural-small-bowel-hematoma-in-a-patient-with-acute-myeloid-leukaemia-receiving-chemotherapy-and-nilotinib
#2
Glenda M Delgado Ramos, Guilherme Piovezani Ramos, Thomas G Cotter
Spontaneous intramural small bowel hematoma (SISBH) is a rare, acute abdominal condition, with increasing incidence in recent years. Excessive anticoagulation with vitamin K antagonists is the most common aetiology. We report the case of a large acute jejunal intramural hematoma in a patient with newly diagnosed acute myeloid leukaemia receiving chemotherapy and nilotinib. The patient presented with abdominal pain, haematochezia, acute anaemia and thrombocytopenia. CT of the abdomen and pelvis revealed SISBH...
September 27, 2017: BMJ Case Reports
https://www.readbyqxmd.com/read/28877032/bowel-endometriosis-a-diagnostic-and-therapeutic-challenge
#3
Beng Kwang Ng, Su Ee Phon, Ani Amelia Zainuddin, Wendy Yin Ling Ng, Nordashima Abd Shukor, Pei Shan Lim
Bowel endometriosis is the most common extragenital manifestation of endometriosis. Clinical suspicion is of utmost importance for achieving its diagnosis. Management of this condition is, however, always challenging to the gynaecologist. We report a case of bowel endometriosis in which the patient presented with dyschezia and haematochezia prior to her menses for the past 2 years. A 44-year-old para two woman presented with worsening dysmenorrhea and dyspareunia. She also experienced dyschezia and haematochezia prior to her menses for the past 2 years...
September 6, 2017: Hormone Molecular Biology and Clinical Investigation
https://www.readbyqxmd.com/read/28763827/-management-of-a-port-catheter-related-superior-vena-cava-thrombosis-in-the-setting-of-active-crohn-s-disease-a%C3%A2-case-report
#4
Ludwig Abel, Britta Uhde, Rolf Dembinski, Konstantin Schraepler
History and clinical findings A 56 year-old woman was admitted to our hospital for treatment of a severe exacerbation of Crohn's disease. During the stay a port catheter was implanted, safeguarding nutrition. A few days later the patient developed symptoms of a severe superior vena cava (SVC) syndrome with dyspnea, cyanosis, headaches and swelling of face and upper extremities. Examination A CT scan showed port catheter-associated SVC thrombosis with complete occlusion of the SVC. Diagnosis There was a coexistence of a port catheter-associated SVC thrombosis with complete occlusion of the SVC and a severe exacerbation of Crohn's disease with haematochezia...
August 2017: Deutsche Medizinische Wochenschrift
https://www.readbyqxmd.com/read/28498330/specific-microrna-pattern-in-colon-tissue-of-young-children-with-eosinophilic-colitis
#5
Zoltán Kiss, Nóra Judit Béres, Erna Sziksz, Bálint Tél, Katalin Borka, András Arató, Attila J Szabó, Gábor Veres
Eosinophilic colitis (EC) is a common cause of haematochezia in infants and young children. The exact pathomechanism is not understood, and the diagnosis is challenging. The role of microRNAs as key class of regulators of mRNA expression and translation in patients with EC has not been explored. Therefore, the aim of the present study was to explore the miRNA profile in EC with respect to eosinophilic inflammation. Patients enrolled in the study (n = 10) had persistent rectal bleeding, and did not respond to elimination dietary treatment...
May 12, 2017: International Journal of Molecular Sciences
https://www.readbyqxmd.com/read/28316386/successful-therapeutic-management-of-canine-isosporosis-in-puppies
#6
Nishiswapna Garanayak, A R Gupta, R C Patra
Four labrador male puppies were confirmed for the Isospora spp infection by direct smear and flotation method following complains of anorexia, haematemesis and haematochezia. The puppies were treated with trimethoprime and sulphamethoxazole @ 40 mg/kg body weight in combination with metronidazole @ 10 mg/kg body weight twice daily for 5 days which was supported with fluid therapy, aniemetics and plasma expanders. All the animals showed completed clinical recovery along with clearing of faecal oocyst.
March 2017: Journal of Parasitic Diseases: Official Organ of the Indian Society for Parasitology
https://www.readbyqxmd.com/read/27943548/use-of-mycophenolate-mofetil-to-treat-immune-mediated-skin-disease-in-14-dogs-a-retrospective-evaluation
#7
Amanda L Ackermann, Elizabeth R May, Linda A Frank
BACKGROUND: Mycophenolate mofetil (MMF) is a lymphocytotoxic immunosuppressive agent used in human and companion animal medicine for the treatment of immune-mediated disease. Mycophenolate mofetil is reported to have reduced myelotoxicity and hepatotoxicity when compared to azathioprine. OBJECTIVES: It was hypothesized that treatment with MMF as a secondary agent with glucocorticoids would be effective in treating immune-mediated skin disease. In addition, adverse effects associated with the drug are reported...
April 2017: Veterinary Dermatology
https://www.readbyqxmd.com/read/27943513/endoscopic-monopolar-coagulation-of-internal-haemorrhoids-a-surgeon-s-experience-of-the-first-100-cases
#8
W-L Loh, S Tan, M S Ngooi, Z K Ong, S S Ngoi
AIM: The purpose of this study was to evaluate one surgeon's initial experience with a novel technique of retroflexed endoscopic coagulation of internal haemorrhoids. METHOD: Patients who presented with symptoms and signs indicating Grade II-III haemorrhoids were counselled before the procedure. Those who were assessed to require an examination of their colon, based on their age and symptoms, underwent a full colonoscopy before treatment of the haemorrhoids. After the procedure, patients were routinely prescribed nonsteroidal anti-inflammatory drugs, antibiotics and laxatives...
January 2017: Colorectal Disease: the Official Journal of the Association of Coloproctology of Great Britain and Ireland
https://www.readbyqxmd.com/read/27658328/a-case-of-hepatic-portal-venous-gas-after-colonoscopy
#9
Tevfik Solakoglu, Sevil O Sari, Huseyin Koseoglu, Murat Basaran, Mustafa Akar, Semnur Buyukasik, Osman Ersoy
Hepatic portal venous gas (HPVG) is a rare radiologic finding that is usually precipitated by intestinal ischaemia, intra-abdominal abscesses, necrotising enterocolitis, abdominal trauma, infectious enteritis, and inflammatory bowel disease. In this study, we present a case of HPVG in a 66-year-old female patient who underwent colonoscopy for evaluation of haematochezia and a review of the literature focused on HPVG following colonoscopy.
September 2016: Arab Journal of Gastroenterology: the Official Publication of the Pan-Arab Association of Gastroenterology
https://www.readbyqxmd.com/read/27559488/haematochezia-from-a-splenic-artery-pseudoaneurysm-communicating-with-transverse-colon-a-case-report-and-literature-review
#10
James O'Brien, Francesca Muscara, Aser Farghal, Irshad Shaikh
Splenic artery aneurysms (SAA) are the third most common intra-abdominal aneurysm. Complications include invasion into surrounding structures often in association with preexisting pancreatic disease. We describe an 88-year-old female, with no history of pancreatic disease, referred with lower gastrointestinal bleeding. CT angiography showed a splenic artery pseudoaneurysm with associated collection and fistula to the transverse colon at the level of the splenic flexure. The pseudoaneurysm was embolised endovascularly with metallic microcoils...
2016: Case Reports in Vascular Medicine
https://www.readbyqxmd.com/read/27107058/a-double-conundrum-concurrent-presentation-of-hashimoto-s-thyroiditis-and-ulcerative-colitis
#11
Gurpreet Singh, Susie Brien, Ellen Taylor
We describe a case of a 31-year-old man who presented with a 3-day history of crampy abdominal pain, anorexia, malaise and diarrhoea of increasing frequency, with the passage of both mucus and haematochezia. The patient's biochemical investigations revealed hyponatraemia, hypothyroidism and elevated inflammatory markers. The patient underwent an ultrasound and fine-needle aspiration of the thyroid and was diagnosed as having Hashimoto's thyroiditis. He was started on thyroxine and fluid was restricted. He was also investigated for alternative causes of hyponatraemia...
April 22, 2016: BMJ Case Reports
https://www.readbyqxmd.com/read/27028211/clinical-presentation-treatment-and-outcome-in-31-dogs-with-presumed-primary-colorectal-lymphoma-2001-2013
#12
I Desmas, J H Burton, G Post, O Kristal, M Gauthier, J F Borrego, A Di Bella, A Lara-Garcia
The objective of this multicentre retrospective study was to describe clinical presentation, treatment and outcome and to determine prognostic factors for dogs with presumed primary colorectal lymphoma (PCRL). A total of 31 dogs were included. The predominant features of PCRL were high grade (n = 18) and immunophenotype B (n = 24). Most dogs were substage b (n = 25) with higher prevalence of haematochezia (n = 20). One dog had surgery only. Thirty dogs received chemotherapy; amongst them 13 had surgery or radiotherapy...
June 2017: Veterinary and Comparative Oncology
https://www.readbyqxmd.com/read/26783491/gastrointestinal-bleeding-and-diffuse-skin-thickening-as-kaposi-sarcoma-clinical-presentation
#13
Sara Querido, Henrique Silva Sousa, Tiago Assis Pereira, Rita Birne, Patrícia Matias, Cristina Jorge, André Weigert, Teresa Adragão, Margarida Bruges, Domingos Machado
A 56-year-old African patient received a kidney from a deceased donor with 4 HLA mismatches in April 2013. He received immunosuppression with basiliximab, tacrolimus, mycophenolate mofetil, and prednisone. Immediate diuresis and a good allograft function were soon observed. Six months later, the serum creatinine level increased to 2.6 mg/dL. A renal allograft biopsy revealed interstitial fibrosis and tubular atrophy grade II. Toxicity of calcineurin inhibitor was assumed and, after a switch for everolimus, renal function improved...
2015: Case Reports in Transplantation
https://www.readbyqxmd.com/read/26712292/paediatric-endoscopy-by-adult-gastroenterologists-in-ile-ife-nigeria-a-viable-option-to-increase-the-access-to-paediatric-endoscopy-in-low-resource-countries
#14
Olusegun I Alatise, Henry Chineme Anyabolu, Oludayo Sowande, David Akinola
BACKGROUND: Paediatric endoscopy performed by adult gastroenterologists is a service delivery model that increases the access of children to endoscopy in countries where paediatric gastroenterologists with endoscopy skills are scarce. However, studies on the usefulness of this model in Nigeria and Sub-Saharan Africa are scarce. We aimed to evaluate the indications, procedures, diagnostic yield and safety of paediatric endoscopy performed by adult gastroenterologists in a Nigerian tertiary health facility...
October 2015: African Journal of Paediatric Surgery: AJPS
https://www.readbyqxmd.com/read/26548121/case-reports-of-adult-colo-colonic-intussusception
#15
O O Ayandipo, A I Abdurrazzaaq, G O Ogun, A T Adeniji-Sofoluwe, A F Ademola, T O Ogundiran
BACKGROUND: Adult colo-colonic intussusception is a rare abnormality and it may pose a diagnostic challenge. OBJECTIVE: To report two cases of adult colo-colonic intussusception with benign lesion as the lead points. METHODS: The Clinical records of the two patients containing the management details were retrieved and reviewed. RESULTS: The 1st case was a 60 year old man presenting with a year history of recurrent left abdominal pain a two week history of fullness left upper and lower abdomen...
March 2015: African Journal of Medicine and Medical Sciences
https://www.readbyqxmd.com/read/26430231/peutz-jeghers-syndrome-early-clinical-expression-of-a-new-stk11-gene-variant
#16
Sara Brito, Marta Póvoas, Juliette Dupont, Ana Isabel Lopes
Genetic heterogeneity has been recognised in Peutz-Jeghers syndrome (PJS) (over 230 STK11 gene mutations reported). We report a rare PJS phenotype with early extensive gastrointestinal (GI) presentation and a new genetic variant. The case presented as haematochezia and mucocutaneous pigmentation (the patient was 3 years of age). Endoscopy showed several polyps throughout the stomach/colon (PJ-type hamartomas); the larger polyps were resected. Small bowel imaging detected multiple jejunum/ileum small polyps...
October 1, 2015: BMJ Case Reports
https://www.readbyqxmd.com/read/26313088/rectal-bleeding-and-endoscopy-need-in-sierra-leone-results-of-a-nationwide-community-based-survey
#17
Barclay T Stewart, Reinou S Groen, Thaim B Kamara, Steve Kwon, T Peter Kingham, Adam L Kushner
BACKGROUND: Low-income and middle-income countries (LMICs) face a large burden of gastrointestinal diseases that benefit from prompt endoscopic diagnosis and treatment. This study aimed to estimate the prevalence of gross rectal bleeding among adults in Sierra Leone. METHODS: A cluster randomised, cross-sectional household survey using the SOSAS tool was undertaken in Sierra Leone. 75 clusters of 25 households with two randomly selected respondents in each were sampled to estimate the prevalence of and disability from rectal bleeding...
April 27, 2015: Lancet
https://www.readbyqxmd.com/read/26242819/-heterotopic-gastric-mucosa-in-the-rectum-report-of-a-case
#18
Pablo Colsa-Gutiérrez, Mahgol Kharazmi-Taghavi, Rocío Daniela Sosa-Medina, José Ignacio Berrío-Obregón, Alfredo Ingelmo-Setién
BACKGROUND: Ectopic gastric mucosa has been described in different locations of the digestive tract, but that of the rectum is the least frequent. CLINICAL CASE: The case is described of a 48 year-old woman being investigated by the gastrointestinal department due to rectal bleeding and rectal tenesmus. Colonoscopy showed a diverticular cavity 3 cm, which was reported by histology as fundic-type heterotopic gastric mucosa. Barium enema and abdominopelvic CT showed a diverticular image at level of the right posterolateral wall of the rectal ampulla...
March 2016: Cirugia y Cirujanos
https://www.readbyqxmd.com/read/26004014/symptomatic-cytomegalovirus-gastrointestinal-infection-with-positive-quantitative-real-time-pcr-findings-in-apparently-immunocompetent-patients-a-case-series
#19
S Bernard, R Germi, J Lupo, M-H Laverrière, V Masse, P Morand, G Gavazzi
Cytomegalovirus (CMV) gastrointestinal disease rarely occurs in immunocompetent patients, and is mainly diagnosed on the basis of histopathological findings. Real-time PCR for CMV DNA quantification is considered to be a useful diagnostic tool, but its place in the diagnostic strategy is not clearly defined. The goal of the study was to describe the clinical and paraclinical features of apparently immunocompetent patients with CMV gastrointestinal disease diagnosed according to quantitative PCR results. In this retrospective study conducted in a 1500-bed tertiary-care centre, we reviewed the case records of apparently immunocompetent patients with positive findings of CMV DNA in gastrointestinal biopsies with compatible symptoms and endoscopic findings...
December 2015: Clinical Microbiology and Infection
https://www.readbyqxmd.com/read/25761296/-a-man-with-haematochezia-and-abdominal-pain
#20
Allard Aukema, Ellert J van Soest
A 83-year-old male was admitted to the Emergency Department with acute haematochezia and abdominal pain. At digital rectal examination multiple soft distensions were palpable. Sigmoidoscopy revealed ischaemia of the rectum with severe gangrene. The patient was discharged after fluid resuscitation. Follow-up sigmoidoscopy 4 weeks later showed a fully recovered rectum.
2015: Nederlands Tijdschrift Voor Geneeskunde
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