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Transoral laser microsurgery

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https://www.readbyqxmd.com/read/29433567/laryngeal-recurrence-sites-in-patients-previously-treated-with-transoral-laser-microsurgery-for-squamous-cell-carcinoma
#1
P Horwich, M H Rigby, C MacKay, J Melong, B Williams, M Bullock, R Hart, J Trites, S M Taylor
BACKGROUND: The laryngeal framework provides a natural barrier preventing tumour spread to extralaryngeal structures. Transoral laser microsurgery (TLM) for laryngeal squamous cell carcinoma (SCC) may violate these boundaries, altering the pathways of tumor spread for potential recurrences. Our project objective is to describe laryngeal SCC recurrence patterns and overall survival in patients requiring total laryngectomy (TL) after TLM. METHODS: Patients undergoing TLM for laryngeal SCC requiring salvage TL were identified from a prospective CO2 laser database containing all patients undergoing TLM for head and neck malignancies at the QEII Health Sciences Center in Halifax, Nova Scotia between March 2002 - May 2014...
February 13, 2018: Journal of Otolaryngology—Head & Neck Surgery
https://www.readbyqxmd.com/read/29392050/minimally-invasive-procedures-for-laryngeal-carcinoma-transoral-endoscopic-laser-and-transoral-robotic-surgery
#2
REVIEW
Özgül Topal
Open partial or total laryngectomies with or without radiotherapy (RT) or chemoradiotherapy (CRT) are the only mainstays in the treatment of laryngeal carcinomas. However, minimally invasive procedures such as transoral endoscopic carbondioxide laser microsurgery (TLM) or transoral robotic surgeries (TRS) are now being increasingly used in selected patients. The laryngeal framework is not disturbed in these procedures; therefore, the postoperative swallowing function improves more rapidly, and routine tracheotomy is not usually required...
March 2017: Turkish Archives of Otorhinolaryngology
https://www.readbyqxmd.com/read/29373328/nature-and-role-of-surgical-margins-in-transoral-laser-microsurgery-for-early-and-intermediate-glottic-cancer
#3
Ivana Fiz, Jan Constantin Koelmel, Christian Sittel
PURPOSE OF REVIEW: Summarize recent findings regarding the impact of margin status on oncologic outcomes and organ preservation, as well as evaluate possible management policies of close and positive margins after transoral laser microsurgery (TLM) for Tis-T2 glottic carcinomas. RECENT FINDINGS: Impact of margin status on survival rates remains controversial, whereas some authors found close and positive margins to be independent risk factors for recurrence and poorer survival rates, others did not find any significant variations compared with negative ones...
January 25, 2018: Current Opinion in Otolaryngology & Head and Neck Surgery
https://www.readbyqxmd.com/read/29306525/cricoarytenoid-joint-ankylosis-classification-and-transoral-laser-microsurgical-treatment
#4
Ihab Atallah, Manjunath Mk, Ahmad Al Omari, Christian Adrien Righini, Paul F Castellanos
OBJECTIVE: This study aimed to describe a graduated approach for effective transoral mobilization of cricoarytenoid joint ankylosis (CJA) in the context of the Bogdasarian system of classifying posterior glottic web-based stenosis (PGWS). STUDY DESIGN: This is a retrospective cohort study through data from medical records and operative notes. A consecutive series of 23 patients who underwent reconstructive transoral laser microsurgery for PGWS with a significant degree of CJA (Bogdasarian grade III-IV) was included in the study...
January 4, 2018: Journal of Voice: Official Journal of the Voice Foundation
https://www.readbyqxmd.com/read/29291278/treatment-preferences-in-patients-with-early-glottic-cancer
#5
Yda van Loon, Martine Hendriksma, Ton P M Langeveld, Martin A de Jong, Rob J Baatenburg de Jong, Elisabeth V Sjögren
OBJECTIVE: For early glottic carcinoma, the 2 main treatment modalities are radiotherapy (RT) and transoral CO2 laser microsurgery (TLM). The aim of this study was to investigate treatment preferences and considerations in patients with early glottic carcinoma (T1-T2) who were given a choice between TLM and RT. SUBJECTS AND METHODS: Patients with early glottic cancer (suspected or confirmed extended T1 or limited T2) were counseled by an ENT-surgeon. A subset of 32 patients was also counseled by a radiotherapist...
December 1, 2017: Annals of Otology, Rhinology, and Laryngology
https://www.readbyqxmd.com/read/29278552/oncologic-and-functional-outcomes-of-patients-treated-with-transoral-co2-laser-microsurgery-or-radiotherapy-for-t2-glottic-carcinoma-a-systematic-review-of-the-literature
#6
Martine Hendriksma, Bas J Heijnen, Elisabeth V Sjögren
PURPOSE OF REVIEW: To give an overview of the laryngeal preservation and functional outcomes of patients treated with transoral CO2 laser microsurgery (TLM) or radiotherapy for T2 glottic carcinoma. This information supports physicians and patients in treatment counselling and choices. RECENT FINDINGS: A recent systematic review showed that local control rates at 5-year did not differ between radiotherapy and TLM for T2 glottic tumours. However, there is a lack of comparative data on laryngeal preservation as well as functional outcomes in T2 glottic carcinoma...
December 22, 2017: Current Opinion in Otolaryngology & Head and Neck Surgery
https://www.readbyqxmd.com/read/29244229/transoral-robotic-surgery-for-residual-and-recurrent-oropharyngeal-cancers-exploratory-study-of-surgical-innovation-using-the-ideal-framework-for-early-phase-surgical-studies
#7
Vinidh Paleri, Hannah Fox, Sarah Coward, Maniram Ragbir, Andrew McQueen, Omar Ahmed, David Meikle, Daniel Saleh, James O'Hara, Max Robinson
BACKGROUND: The purpose of this study was to identify the role of transoral robotic surgery (TORS) in the management of residual and recurrent oropharyngeal cancer. METHODS: IDEAL (Idea, Development, Exploration, Assessment, Long-term Follow-up) 2a framework. RESULTS: Of 26 patients assessed for TORS, 21 underwent the procedure, 5 underwent open resection (4 due to unsuitable anatomy/tumor extent and 1 on the basis of patient choice). Three patients underwent intraoperative ultrasound-assisted robotic resection, and 3 received robotic-assisted free flap inset...
December 15, 2017: Head & Neck
https://www.readbyqxmd.com/read/29238695/high-frequency-jet-ventilation-during-transoral-laser-microsurgery-for-tis-t2-laryngeal-cancer
#8
Francesco Mora, Francesco Missale, Fabiola Incandela, Marta Filauro, Giampiero Parrinello, Alberto Paderno, Palmiro Della Casa, Cesare Piazza, Giorgio Peretti
Background: Transoral laser microsurgery (TLM) for early to intermediate laryngeal squamous cell cancer (SCC) can be technically challenging when adequate exposure of the posterior laryngeal compartment is required due to the presence of the orotracheal tube. The goal of our study was to analyze the efficacy of high frequency jet ventilation (HFJV) in achieving appropriate laryngeal exposure and safe oncologic resection of lesions located in such a position. Methods: We reviewed the clinical records of 62 patients affected by Tis-T2 SCC of the posterior laryngeal compartment treated by TLM between 02/2012 and 12/2016...
2017: Frontiers in Oncology
https://www.readbyqxmd.com/read/29214640/management-of-head-and-neck-primary-unknown-squamous-cell-carcinoma-using-combined-positron-emission-tomography-computed-tomography-and-transoral-laser-microsurgery
#9
Victoria Kuta, Blair Williams, Matthew Rigby, Robert Hart, Jonathan Trites, Colin MacKay, S Mark Taylor
OBJECTIVES/HYPOTHESIS: The unknown primary of the neck is commonly encountered by the head and neck surgeon. Despite the exhaustive diagnostic tools employed in traditional detection protocols, many unknown primaries are not found, and the patient is subjected to wide-field radiation and chemotherapy during treatment. Localizing the primary tumor has demonstrated therapeutic benefits, improved quality of life, and overall survival. The authors' objective was to determine the efficacy of a new management protocol for unknown primaries of the head and neck...
December 7, 2017: Laryngoscope
https://www.readbyqxmd.com/read/29119321/conservative-treatment-for-advanced-t3-t4-laryngeal-cancer-meta-analysis-of-key-oncological-outcomes
#10
REVIEW
Giuditta Mannelli, Maria Silvia Lazio, Paolo Luparello, Oreste Gallo
GOAL: Controversies exist regarding the treatment of advanced laryngeal carcinomas. The purpose of this systematic review was to evaluate the oncologic outcomes of both transoral laser and open partial laryngectomies for advanced (T3-T4) squamous cell laryngeal cancers management. INTRODUCTION: A systematic review of literature was led searching for articles mentioning the following terms: advanced (T3-T4) laryngeal cancer AND laser; AND open partial laryngectomy; AND transoral laser microsurgery; AND cordectomy; AND conservative surgery; AND tracheohyoidopexy or tracheohyoidoepiglottopexy; AND supratracheal partial laryngectomy; AND supracricoid partial laryngectomy; AND cricohyoidopexy or cricohyoidoepiglottopexy...
November 8, 2017: European Archives of Oto-rhino-laryngology
https://www.readbyqxmd.com/read/29098372/radiological-tumor-thickness-as-a-risk-factor-for-local-recurrence-in-early-glottic-cancer-treated-with-laser-cordectomy
#11
Ho-Jin Son, Yoon Se Lee, Ja Yoon Ku, Jong-Lyel Roh, Seung-Ho Choi, Soon Yuhl Nam, Sang Yoon Kim
OBJECTIVES: Despite the excellent prognosis of early glottic cancer (T1-T2), the significance of preoperatively measured tumor thickness has not been elucidated. We evaluated the role of tumor thickness measured using computed tomography (CT) as a predictive factor for recurrence of early glottic cancer after transoral laser microsurgery (TLM). METHODS: The medical records of 134 patients who were diagnosed with early glottic squamous cell carcinoma and underwent TLM were reviewed...
November 2, 2017: European Archives of Oto-rhino-laryngology
https://www.readbyqxmd.com/read/29046085/transoral-laser-surgery-for-laryngeal-carcinoma-has-steiner-achieved-a-genuine-paradigm-shift-in-oncological-surgery
#12
A T Harris, A Tanyi, R D Hart, J Trites, M H Rigby, J Lancaster, A Nicolaides, S M Taylor
Transoral laser microsurgery applies to the piecemeal removal of malignant tumours of the upper aerodigestive tract using the CO2 laser under the operating microscope. This method of surgery is being increasingly popularised as a single modality treatment of choice in early laryngeal cancers (T1 and T2) and occasionally in the more advanced forms of the disease (T3 and T4), predominantly within the supraglottis. Thomas Kuhn, the American physicist turned philosopher and historian of science, coined the phrase 'paradigm shift' in his groundbreaking book The Structure of Scientific Revolutions...
October 19, 2017: Annals of the Royal College of Surgeons of England
https://www.readbyqxmd.com/read/28976011/oncologic-results-and-quality-of-life-in-patients-with-squamous-cell-carcinoma-of-hypopharynx-after-transoral-laser-microsurgery
#13
Li-Ting Hung, Hsin-I Huang, Ling-Wei Wang, Muh-Hwa Yang, Pen-Yuan Chu
OBJECTIVE: Transoral laser microsurgery (TLM) is an alternative method for organ preservation in squamous cell carcinoma of hypopharynx (HPSCC). The purpose of this study was to analyze the oncologic results and quality of life (QOL) in HPSCC patients after TLM. METHODS: Forty-six patients who underwent TLM were included, 34 of them had QOL evaluations. The QOL analyses were measured with EORTC QLQ-C-30, QLQ-H&N35, VHI-30, and MDADI at least 6 months postoperatively...
October 4, 2017: Lasers in Surgery and Medicine
https://www.readbyqxmd.com/read/28929221/therapeutic-modalities-and-oncologic-outcomes-in-the-treatment-of-t1b-glottic-squamous-cell-carcinoma-a-systematic-review
#14
REVIEW
Federico Maria Gioacchini, Michele Tulli, Shaniko Kaleci, Stefano Bondi, Mario Bussi, Massimo Re
T1a and T1b glottic squamous cell carcinoma (SCC) are often analyzed together by authors who investigate the oncologic outcomes achieved after different therapeutic options. Nevertheless, T1b definitely represents a more advanced tumor stage compared to T1a glottic SCC. The objective of this review was first to analyze the overall success rates in the treatment of patients affected by T1b glottic SCC. Moreover, a subgroup analysis was planned to specifically compare the outcomes obtained with radiotherapy (RT), transoral laser microsurgery (TLM) and open partial laryngectomies (OPL)...
December 2017: European Archives of Oto-rhino-laryngology
https://www.readbyqxmd.com/read/28895160/oncologic-outcomes-of-ktp-laser-surgery-versus-radiation-for-t1-glottic-carcinoma
#15
Jamal Ahmed, Ahmed Sherif Gabr Ibrahim, Laura M Freedman, David E Rosow
OBJECTIVES/HYPOTHESIS: To characterize outcomes for patients who underwent transoral microsurgery with potassium titanyl phosphate (KTP) laser resection of early glottic cancers and to compare outcomes with patients who received external beam radiation therapy. STUDY DESIGN: Retrospective cohort study. METHODS: The history of patients with T1 glottic carcinoma treated with curative primary radiation or transoral KTP laser resection was reviewed...
September 12, 2017: Laryngoscope
https://www.readbyqxmd.com/read/28895157/laryngeal-exposure-and-margin-status-in-glottic-cancer-treated-by-transoral-laser-microsurgery
#16
Cesare Piazza, Alberto Paderno, Paola Grazioli, Francesca Del Bon, Nausica Montalto, Pietro Perotti, Riccardo Morello, Marta Filauro, Piero Nicolai, Giorgio Peretti
OBJECTIVE: Laryngeal exposure is one of the most limiting factors in transoral laser microsurgery (TLM) for glottic cancer. We evaluated the correlation between the degree of laryngeal exposure, as assessed by an easy previously described scoring tool (Laryngoscore), and histopathologic surgical margin status after TLM. STUDY DESIGN: Prospective evaluation of 147 patients affected by Tis-T2 glottic cancer treated by TLM with curative intent between January 2012 and April 2016...
September 12, 2017: Laryngoscope
https://www.readbyqxmd.com/read/28873031/surgical-treatment-for-early-stage-glottic-carcinoma-with-involvement-of-the-anterior-commissure
#17
Philipp Wolber, David Schwarz, Thoralf Stange, Magdalene Ortmann, Matthias Balk, Andreas Anagiotos, Antoniu-Oreste Gostian
Objective Assessment of the value of transoral laser microsurgery (TLM) compared with open surgery (OS) for early stage squamous cell carcinoma of the glottic larynx with special regard to involvement of the anterior commissure (AC). Study Design Case series with chart review. Setting Tertiary care otolaryngology clinic. Subjects and Methods Review of clinicopathological data of all patients with previously untreated T1a, T1b, and T2 glottic squamous cell carcinoma of the larynx who were consecutively enrolled over a 10-year period (January 1, 1992, to December 31, 2002)...
February 2018: Otolaryngology—Head and Neck Surgery
https://www.readbyqxmd.com/read/28854985/-cutting-through-tumour-in-head-and-neck-cancer-still-a-taboo
#18
R de Bree, S M Willems, L M Janssen, M W M van den Brekel
When resecting head and neck tumours, the aim is mostly to strive for en bloc resection with sufficiently large tumour-free margins. If this is not possible, as is frequently the case with transoral laser microsurgery and endonasal endoscopic surgery, multiblock resection can be carried out by cutting through the tumour. With this approach, it is also essential that the final resection margins are tumour-negative. In such cases, surgeon and pathologist together should pay extra attention to tissue orientation and outer resection margins...
2017: Nederlands Tijdschrift Voor Geneeskunde
https://www.readbyqxmd.com/read/28819810/laser-assisted-surgery-of-the-upper-aero-digestive-tract-a-clarification-of-nomenclature-a-consensus-statement-of-the-european-laryngological-society
#19
Marc Remacle, Christoph Arens, Mostafa Badr Eldin, Guillermo Campos, Carlos Chiesa Estomba, Pavel Dulguerov, Ivana Fiz, Anastasios Hantzakos, Jerôme Keghian, Francesco Mora, Nayla Matar, Giorgio Peretti, Cesare Piazza, Gregory N Postma, Vyas Prasad, Elisabeth Sjogren, Frederik G Dikkers
Acronyms and abbreviations are frequently used in otorhinolaryngology and other medical specialties. CO2 laser-assisted transoral surgery of the pharynx, the larynx and the upper airway is a family of commonly performed surgical procedures termed transoral laser microsurgery (TLM). The abbreviation TLM can be confusing because of alternative modes of delivery. Classification and definition of the different types of procedures, performed transorally or transnasally, are proposed by the Working Committee for Nomenclature of the European Laryngological Society, emphasizing the type of laser used and the way this laser is transmitted...
August 17, 2017: European Archives of Oto-rhino-laryngology
https://www.readbyqxmd.com/read/28695624/life-quality-improvement-in-hoarse-patients-with-early-glottic-cancer-after-transoral-laser-microsurgery
#20
Li-Jen Hsin, Wan-Ni Lin, Tuan-Jen Fang, Li-Ang Lee, Chung-Jan Kang, Bing-Shan Huang, Chien-Yu Lin, Kang-Hsing Fan, Ngan-Ming Tsang, Cheng-Lung Hsu, Joseph Tung-Chieh Chang, Chun-Ta Liao, Tzu-Chen Yen, Kai-Ping Chang, Hsiu-Feng Chuang, Hsueh-Yu Li
BACKGROUND: The purpose of this study was to evaluate the recovery kinetics of voice and quality of life (QOL) over time in patients with early glottic cancer who underwent transoral laser microsurgery (TLM). METHODS: A prospective cohort study was conducted in which acoustic and aerodynamic voice assessments and QOL analyses were done using health-related questionnaires (European Organization for Research and Treatment of Cancer Quality of Life Questionnaire-Core 30-questions [EORTC-QLQ-C30] and European Organization for Research and Treatment of Cancer Quality of Life Questionnaire-Head and Neck 35-questions [EORTC-QLQ-H&N35]) were administered at designated times...
July 11, 2017: Head & Neck
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