keyword
MENU ▼
Read by QxMD icon Read
search

Transoral laser microsurgery

keyword
https://www.readbyqxmd.com/read/28028607/transoral-laser-microsurgery-for-t1b-glottic-cancer-review-of-51-cases
#1
Bernhard G Weiss, Friedrich Ihler, Yiannis Pilavakis, Hendrik A Wolff, Martin Canis, Christian Welz, Wolfgang Steiner
For the treatment of T1b glottic carcinoma, different treatment options, such as transoral laser microsurgery, open surgical techniques, and primary radiotherapy, are under discussion. In this context, the aim of the present study was to describe oncologic results and complication rates of transoral laser microsurgery in treatment of T1b glottic carcinoma. This is a retrospective unicenter chart review of patients treated at an academic tertiary referral center between 1986 and 2006. Fifty-one previously untreated T1b cases were exclusively treated by transoral laser microsurgery and included into this study, 47 were male, and 4 were female...
December 27, 2016: European Archives of Oto-rhino-laryngology
https://www.readbyqxmd.com/read/28025603/evidence-and-evidence-gaps-of-laryngeal-cancer-surgery
#2
REVIEW
Susanne Wiegand
Surgical treatment of laryngeal cancer has been established for decades. In addition to total laryngectomy, which was first performed in 1873, a large number or organ preservation surgical techniques, like open partial laryngectomy, transoral laser microsurgery, and transoral robotic surgery have been developed. Studies on laryngeal cancer surgery are mainly retrospective case series and cohort studies. The evolution of chemoradiation protocols and their analysis in prospective randomized trials have led to an increasing acceptance of non-surgical treatment procedures...
2016: GMS Current Topics in Otorhinolaryngology, Head and Neck Surgery
https://www.readbyqxmd.com/read/27966287/transoral-laser-microsurgery-versus-radiation-therapy-in-the-management-of-t1-and-t2-laryngeal-glottic-carcinoma-which-modality-is-cost-effective-within-the-uk
#3
Matthew Prettyjohns, Stuart Winter, Cyrus Kerawala, Vinidh Paleri
OBJECTIVES: To identify the most cost effective treatment strategy in patients with early stage (T1and T2) cancers of the laryngeal glottis. DESIGN: A Markov decision model populated using data from updated systematic reviews and meta analyses, with attributable costs from NHS sources. Data on local control and mortality was obtained from updates of existing systematic reviews conducted for the NICE guideline on cancer of the upper aerodigestive tract. Procedure costs were sourced from NHS reference costs 2013/14 by applying tariffs associated with the appropriate health resource group code...
December 14, 2016: Clinical Otolaryngology
https://www.readbyqxmd.com/read/27966051/transoral-laser-microsurgery-versus-radiotherapy-for-t1-glottic-carcinoma-a-systematic-review-and-meta-analysis
#4
Hai-Lan Mo, Jie Li, Xiang Yang, Feng Zhang, Jun-Wei Xiong, Zhi-Ling Yang, Jian Tan, Bing Li
Transoral laser microsurgery (TLM) and radiotherapy (RT) are both accepted treatment modalities for glottic cancer. The objective of the study was to assess the oncologic outcomes and life quality of TLM in comparison with RT for T1 glottic carcinoma. We searched Medline/PubMed, Web of knowledge, EMBASE, the Cochrane Library, the Wiley online library, Springer, Google, China National Knowledge Infrastructure (CNKI), etc. We screened the literature, assessed the quality of the studies, and extracted the relevant data through the establishment of inclusion and exclusion criteria...
December 13, 2016: Lasers in Medical Science
https://www.readbyqxmd.com/read/27958597/salvage-total-laryngectomy-after-conservation-laryngeal-surgery-for-recurrent-laryngeal-squamous-cell-carcinoma
#5
A De Virgilio, A Greco, F Bussu, A Gallo, D Rosati, S-H Kim, C-C Wang, M Conte, G Pagliuca, M De Vincentiis
The aim of the present study was to evaluate the oncological efficacy of salvage total laryngectomy in patients who had previously undergone supracricoid partial laryngectomy or transoral laser microsurgery for treatment of laryngeal squamous cell carcinoma. We retrospectively reviewed the medical, surgical and pathological records of 35 patients who underwent salvage total laryngectomy after recurrence of laryngeal cancer (following supracricoid partial laryngectomy or transoral laser microsurgery). Kaplan-Meier survival curves as well as univariate and multivariate analyses of prognostic factors were performed...
October 2016: Acta Otorhinolaryngologica Italica
https://www.readbyqxmd.com/read/27943254/minimally-invasive-surgery-versus-radiotherapy-chemoradiotherapy-for-small-volume-primary-oropharyngeal-carcinoma
#6
REVIEW
James Howard, Liam Masterson, Raghav C Dwivedi, Faruque Riffat, Richard Benson, Sarah Jefferies, Piyush Jani, James R Tysome, Chris Nutting
BACKGROUND: More than 400,000 cases of oropharyngeal squamous cell carcinoma (OPSCC) are diagnosed each year worldwide and the incidence is rising, partly as a result of human papillomavirus. Human papillomavirus-associated OPSCC affects younger patients and often presents at a higher stage; however, it is associated with a better prognosis.Until recently, first-line management of OPSCC involved chemoradiotherapy, as research had demonstrated comparable survival outcomes when compared with open surgery, with significantly decreased morbidity...
December 11, 2016: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/27863075/transoral-laser-microsurgery-versus-radiotherapy-for-t2-glottic-squamous-cell-carcinoma-a-systematic-review-of-local-control-outcomes
#7
L Warner, K Lee, J J Homer
BACKGROUND: Systematic reviews comparing treatment of early glottic cancer with transoral surgery or radiotherapy demonstrate similar oncological outcomes. Most studies of 'early-stage' laryngeal cancer include Tis, T1a, T1b and T2 cases. The data are dominated by patients with T1 and Tis tumours, although extrapolating these results and applying them for T2 cases may be inappropriate. No previous systematic reviews have focused on T2 cancers as a separate group. OBJECTIVE OF REVIEW: This review compares local control outcomes for T2 glottic squamous cell carcinoma, treated with transoral microsurgery or external beam radiotherapy...
November 10, 2016: Clinical Otolaryngology
https://www.readbyqxmd.com/read/27812692/radiotherapy-characteristics-and-outcomes-for-head-and-neck-carcinoma-of-unknown-primary-vs-t1-base-of-tongue-carcinoma
#8
Ali Hosni, Peter R Dixon, Anupam Rishi, Michael Au, Wei Xu, Yuyao Song, Douglas B Chepeha, David P Goldstein, Shao Hui Huang, John Kim, Brian O'Sullivan, John Waldron, Scott V Bratman, John R de Almeida
Importance: Transoral robotic surgery- or transoral laser microsurgery-assisted lingual tonsillectomy may improve the identification rate of hidden base-of-tongue (BOT) carcinoma presenting as head or neck carcinoma of unknown primary (CUP) site. Objective: To evaluate the potential impact of lingual tonsillectomy in CUP site by comparing differences in radiotherapy volumes, dosimetry, and clinical outcomes for CUP site and T1-category BOT carcinoma. Design, Setting, and Participants: Retrospective study of 115 patients treated at a tertiary cancer center between January 1, 2005, and December 31, 2013, that included patients with BOT carcinoma (category T1N1-3M0) and CUP site (category T0N1-3M0) with known p16 status...
December 1, 2016: JAMA Otolaryngology—Head & Neck Surgery
https://www.readbyqxmd.com/read/27778345/evaluating-organ-preservation-outcome-as-treatment-endpoint-for-t1an0-glottic-cancer
#9
Tsu-Hui Hubert Low, David Yeh, Tina Zhang, Rakhna Araslanova, J Alex Hammond, David Palma, Nancy Read, Varagur Venkatesan, S Danielle MacNeil, John Yoo, Anthony Nichols, Kevin Fung
OBJECTIVES/HYPOTHESIS: Common endpoints in reporting the outcomes for early glottic cancer do not highlight the importance of organ preservation. We evaluated the treatment outcomes among patients with T1aN0 laryngeal cancer with laryngectomy-free disease-specific survival (LFS-DSS), which is defined as time to total laryngectomy or time to death from cancer cause, against all other endpoints. STUDY DESIGN: Outcome research on an institutional database. METHODS: A retrospective review covered all consecutive patients from 2003 to 2013...
October 25, 2016: Laryngoscope
https://www.readbyqxmd.com/read/27709626/long-term-quality-of-life-after-transoral-laser-microsurgery-for-laryngeal-carcinoma
#10
Meritxell Valls-Mateus, Alexis Ortega, José Luis Blanch, Francesc Sabater, Manuel Bernal-Sprekelsen, Isabel Vilaseca
BACKGROUND AND OBJECTIVES: Previous studies showed good short-term Quality of life (QOL) after Transoral Laser Microsurgery (TLM) for laryngeal cancer. Here, we aimed to evaluate QOL after TLM in the long-term. METHODS: Prospective longitudinal study. Sixty-two consecutive disease-free patients were evaluated using UW-QOL v4 and SF-12 questionnaires, 1 and 5 years after TLM. Changes over time were assessed according to age, location, and tumor size. Long-term VHI-10 was also evaluated...
December 2016: Journal of Surgical Oncology
https://www.readbyqxmd.com/read/27686889/treatment-outcome-of-vocal-cord-leukoplakia-by-transoral-laser-microsurgery
#11
Shih-Wei Yang, Wei-Chieh Chao, Yun-Shien Lee, Liang-Che Chang, Tsan-Yu Hsieh, Tai-An Chen, Cheng-Ming Luo
The aim of this study is to evaluate the treatment outcome and analyze the associated factors of postoperative recurrence in patients who received transoral laser microsurgery for vocal cord leukoplakia. The demographic, histopathological data were retrospectively reviewed and the factors associated with recurrence of vocal leukoplakia after surgery were analyzed statistically. A total of 44 patients, including 36 males and 8 females, with a mean age of 50.4 ± 13.4 years, were enrolled. All the patients received excision of the vocal leukoplakia by carbon dioxide laser (2-4 Watt, ultrapulse mode) under general anesthesia...
January 2017: Lasers in Medical Science
https://www.readbyqxmd.com/read/27674536/transoral-endoscopic-laser-microsurgery-or-concurrent-chemoradiation-therapy-for-t2n0-larynx-cancer
#12
Y Y Wu, T J Fang, J T C Chang
No abstract text is available yet for this article.
October 1, 2016: International Journal of Radiation Oncology, Biology, Physics
https://www.readbyqxmd.com/read/27635749/oncological-and-survival-outcomes-following-transoral-robotic-surgery-versus-transoral-laser-microsurgery-for-the-treatment-of-oropharyngeal-squamous-cell-carcinoma-a-systematic-review-protocol
#13
Sabapathy Giridhar Suren Krishnan, Kandiah Umapathysivam, Craig Lockwood, John-Charles Hodge
The objective of this systematic review is to synthesize the best available evidence regarding the oncological and survival outcomes (as measured by disease control, disease-free survival, disease-specific survival and overall survival) of transoral robotic surgery (TORS) versus transoral laser microsurgery (TLM) in the treatment of oropharyngeal squamous cell carcinoma in adults (aged 18 years or older). Specifically the review questions are:1 Is there a difference in oncological outcomes between a traditional "Halstedian" en bloc tumor resection technique used in TORS versus a modern segmental tumor dissection technique used in TLM?2 Does one surgical approach confer better oncological outcomes with respect to a particular patient subgroup, such as patients with a positive human papilloma virus status or patient's with different tumor T-stages?...
August 2016: JBI Database of Systematic Reviews and Implementation Reports
https://www.readbyqxmd.com/read/27578610/management-of-primary-t1-t4-glottic-squamous-cell-carcinoma-by-transoral-laser-microsurgery
#14
Andrew T Day, Parul Sinha, Brian Nussenbaum, Dorina Kallogjeri, Bruce H Haughey
OBJECTIVES/HYPOTHESIS: Evaluate the oncologic outcomes of patients with early and select advanced primary glottic squamous cell carcinoma (SCCa) managed by transoral laser microsurgery (TLM). STUDY DESIGN: Retrospective cohort study. METHODS: Ninety cases of TLM-managed primary glottic SCCa were identified retrospectively using a prospectively collected database. RESULTS: Outcomes of patients with pTis-pT2a disease (n = 65) and pT2b-pT4a disease (n = 25) were, respectively: 5-year local control, 86...
August 31, 2016: Laryngoscope
https://www.readbyqxmd.com/read/27557483/reconstructive-transoral-laser-microsurgery-for-posterior-glottic-web-with-stenosis
#15
Ihab Atallah, M Krishniah Manjunath, Ahmad Al Omari, Christian Adrien Righini, Paul F Castellanos
OBJECTIVES/HYPOTHESIS: To demonstrate that reconstructive transoral laser microsurgical (R-TLM) techniques can be used for the treatment of symptomatic laryngeal posterior glottic web-based stenosis (PGWS) in a large cohort of patients utilizing a postcricoid mucosal advancement flap (PCMAF). STUDY DESIGN: Retrospective cohort review. METHODS: A consecutive series of patients with PGWS who underwent R-TLM using a PCMAF were reviewed for outcomes...
August 24, 2016: Laryngoscope
https://www.readbyqxmd.com/read/27491319/will-the-mininvasive-approach-challenge-the-old-paradigms-in-oral-cancer-surgery
#16
G Tirelli, S Zacchigna, F Boscolo Nata, E Quatela, R Di Lenarda, M Piovesana
In the genome era, the achievement of a safe and complete resection of oral cancers remains a challenge for surgeons. Margin length at histopathological examination is still considered the main indicator of oncological radicality. However, this parameter is fraught by major limitations. Cancer aggressiveness, and in particular its ability to spread in the surrounding tissue, most probably influences loco-regional control and prognosis more than margin length. Unfortunately, no molecular markers are currently available to predict tumor aggressiveness pre-operatively...
August 4, 2016: European Archives of Oto-rhino-laryngology
https://www.readbyqxmd.com/read/27453475/retrospective-analysis-of-factors-influencing-oncologic-outcome-in-590-patients-with-early-intermediate-glottic-cancer-treated-by-transoral-laser-microsurgery
#17
Mohssen Ansarin, Augusto Cattaneo, Luigi De Benedetto, Stefano Zorzi, Francesca Lombardi, Daniela Alterio, Maria Cossu Rocca, Daniele Scelsi, Lorenzo Preda, Fausto Chiesa, Luigi Santoro
BACKGROUND: The purpose of this study was to identify the factors influencing oncologic outcomes for patients with early-intermediate glottic cancer treated by transoral laser microsurgery (TLM). METHODS: This was a retrospective mono-institutional study. A total of 590 patients with cTis-cT3 glottic cancer underwent TLM with curative intent. RESULTS: TLM alone was performed in 538 patients (91.2%) and TLM followed by adjuvant radiotherapy (RT) was done in 52 (8...
January 2017: Head & Neck
https://www.readbyqxmd.com/read/27435595/telephonic-voice-intelligibility-after-laryngeal-cancer-treatment-is-therapeutic-approach-significant
#18
Erika Crosetti, Marco Fantini, Giulia Arrigoni, Laura Salonia, Agata Lombardo, Alessio Atzori, Valentina Panetta, Antonio Schindler, Andy Bertolin, Giuseppe Rizzotto, Giovanni Succo
The aim was to investigate telephonic voice intelligibility in patients treated for laryngeal cancer using different approaches. In total, 90 patients treated for laryngeal cancer using different approaches and 12 healthy volunteers were recruited. Each patient and each healthy control read a list of words and sentences during a telephone call. Six auditors listened to each telephonic recording and transcribed the words and sentences they understood. Mean intelligibility rates for each treatment were assessed and compared...
July 19, 2016: European Archives of Oto-rhino-laryngology
https://www.readbyqxmd.com/read/27413401/transoral-co2-laser-microsurgery-outcomes-for-early-glottic-carcinomas-t1-t2
#19
Carlos Miguel Chiesa Estomba, Frank Alberto Betances Reinoso, Alejandra Osorio Velasquez, Jose Luis Rodriguez Fernandez, Jose Luis Fariña Conde, Carmelo Santidrian Hidalgo
INTRODUCTION: Transoral laser microsurgery (TLM) has won territory in larynx oncology, establishing itself as an effective option in treatment of glottic, supraglottic, and hypopharynx tumors. Its advantages include limited resections, a reduction in number of tracheostomies, and the use of nasogastric tubes. Moreover, its oncological benefits are similar to those from open surgery in patients with early or advanced stages, when correctly selected. OBJECTIVE: The objective of this study is to review oncologic outcomes obtained with the treatment of a series of glottic tumors, treated by TLM...
July 2016: International Archives of Otorhinolaryngology
https://www.readbyqxmd.com/read/27373106/-the-review-of-transoral-laser-microsurgery-in-laryngeal-cancer
#20
REVIEW
Bin Xu, Jihua Wang, Xuping Xiao
Transoral laser microsurgery (TLM) has developed more than 40 years in the treatment of laryngeal cancer. TLM is especially important in the minimally invasive surgery of laryngeal carcinoma. Compared with the traditional open surgery, it is a major breakthrough, which has the significant advantages such as safety, effectiveness, low rate of local recurrence and high rate of larynx preservation. Not only can cure early laryngeal cancer, but also more and more the use of TLM in advanced supraglottic and glottic laryngeal cancer were reported...
February 2016: Journal of Clinical Otorhinolaryngology, Head, and Neck Surgery
keyword
keyword
104560
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"