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peptic ulcer perforation

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https://www.readbyqxmd.com/read/29724988/total-gastric-necrosis-due-to-mucormycosis-a-rare-case-of-gastric-perforation
#1
Salah Termos, Feras Othman, Mohammad Alali, Bader M S Al Bader, Talal Alkhadher, Wael Fathi Hassanaiah, Ali Taqi, Abhijit Sapkal
BACKGROUND Spontaneous gastric perforation is usually a complication of peptic ulcer disease, or a postoperative complication resulting from gastric torsion. Mucormycosis (or zygomycosis) is an uncommon opportunistic fungal infection that is usually seen in immunocompromised patients and is associated with significant morbidity and mortality. This report is of a rare case of spontaneous gastric perforation due to mucormycosis infection. CASE REPORT A 52-year-old woman, with a past medical history of heroin abuse, diabetes mellitus, hypertension, and chronic kidney disease treated by dialysis, presented to the emergency department with cellulitis of the arms...
May 4, 2018: American Journal of Case Reports
https://www.readbyqxmd.com/read/29716802/perforated-duodenal-ulcers-after-roux-y-gastric-bypass
#2
Denise Pohl, Gregoire Schmutz, Gabriel Plitzko, Dino Kröll, Philipp Nett, Yves Borbély
Even though the incidence of complicated peptic ulcer disease (PUD) has decreased in the last decades, it remains a condition with a significant mortality. Whilst diagnosis and treatment of PUD in morbidly obese patients can be challenging, patients with excluded segments - such as after Roux-Y Gastric Bypass (RYGB) - present an even greater problem, as the subsequent altered anatomy impedes the common modalities used for diagnostic and therapeutic measures. We report the cases of two patients after RYGB with perforated duodenal ulcers in the intention to highlight problems regarding diagnosis and treatment...
April 25, 2018: American Journal of Emergency Medicine
https://www.readbyqxmd.com/read/29659470/meta-analysis-of-perioperative-outcomes-of-acute-laparoscopic-vs-open-repair-of-perforated-gastroduodenal-ulcers
#3
Roberto Cirocchi, Kjetil Soreide, Salomone Di Saverio, Elena Rossi, Alberto Arezzo, Mauro Zago, Iosief Abraha, Nereo Vettoretto, Massimo Chiarugi
BACKGROUND: Surgery is the treatment of choice for perforated peptic ulcer disease (PUD). The aim of the present review is to compare the perioperative outcomes of acute laparoscopic versus open repair for PUD. METHODS: A systematic literature search was performed for randomized controlled trials (RCTs) published in PubMed, SCOPUS and Web of Science RESULTS: The search included eight RCTs: 615 patients comparing laparoscopic (307 patients) versus open peptic perforated ulcer repair (308 patients)...
April 13, 2018: Journal of Trauma and Acute Care Surgery
https://www.readbyqxmd.com/read/29618372/prehospital-triage-of-patients-diagnosed-with-perforated-peptic-ulcer-or-peptic-ulcer-bleeding-an-observational-study-of-patients-calling-1-1-2
#4
Kasper Bonnesen, Kristian D Friesgaard, Morten T Boetker, Lone Nikolajsen
BACKGROUND: Triage systems are used in emergency medical services to systematically prioritize prehospital resources according to individual patient conditions. Previous studies have shown cases of preventable deaths in emergency medical services even when triage systems are used, indicating a potential undertriage among some conditions. The aim of this study was to investigate the triage level among patients diagnosed with perforated peptic ulcer (PPU) or peptic ulcer bleeding (PUB)...
April 5, 2018: Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine
https://www.readbyqxmd.com/read/29613995/perforation-of-a-peptic-ulcer-in-a-hiatal-hernia-into-the-left-ventricle-with-systemic-air-and-food-embolism
#5
Ikumi Igarashi, Keishi Suzuki, Fumi Hosono, Azusa Ichinose, Shoko Abe, Akira Sugiyama, Yasutomo Sekido
Perforation of a peptic ulcer into the ventricle is uncommon, and the definitive diagnosis is difficult in living patients. We herein report a case of perforation of a peptic ulcer in a hiatal hernia into the left ventricle with systemic air and food embolism. This is the first case report of the perforation diagnosed by computed tomography and confirmed by autopsy. Computed tomography was useful for the diagnosis of perforation into the ventricle.
April 2, 2018: Journal of Computer Assisted Tomography
https://www.readbyqxmd.com/read/29571554/imaging-manifestations-of-peptic-ulcer-disease-on-computed-tomography
#6
Arthur H Baghdanian, Armonde A Baghdanian, Shilpa Puppala, Michele Tana, Michael A Ohliger
Although the overall prevalence of peptic ulcer disease (PUD) has decreased in modern times, its actual incidence may be underestimated owing to the nonspecific clinical presentations patients' manifest. The potential lethal complications that can result from PUD include life-threatening abdominal hemorrhage and bowel perforation that result in significant morbidity and mortality. Computed tomography (CT) imaging historically lacks specificity in detecting PUD-related pathology in the stomach and proximal small bowel segments...
April 2018: Seminars in Ultrasound, CT, and MR
https://www.readbyqxmd.com/read/29470633/feasibility-of-a-novel-laparoscopic-technique-with-unidirectional-knotless-barbed-sutures-for-the-primary-closure-of-duodenal-ulcer-perforation
#7
Tae-Han Kim, Ji-Ho Park, Sang-Ho Jeong, Jin-Kwon Lee, Seung-Jin Kwag, Ju-Yeon Kim, Woohyung Lee, Jung-Woo Woo, Jae Yool Jang, Eun-Jin Song, Taejin Park, Chi-Young Jeong, Young-Tae Ju, Eun-Jung Jung, Soon-Chan Hong, Sang-Kyung Choi, Woo-Song Ha, Young-Joon Lee
BACKGROUND: Laparoscopic primary repair is one of the main procedures used for perforated gastric ulcers, and this technique requires reproducible and secure suturing. The aim of this study was to investigate the safety and efficacy of a novel continuous suture method with barbed sutures during laparoscopic repair for perforated peptic ulcers. PATIENTS AND METHODS: Clinical data from 116 consecutive patients undergoing laparoscopic repair for perforated peptic ulcers were collected between November 2009 and October 2015...
February 22, 2018: Surgical Endoscopy
https://www.readbyqxmd.com/read/29448921/evaluation-of-risk-factors-for-perforated-peptic-ulcer
#8
Kazuki Yamamoto, Osamu Takahashi, Hiroko Arioka, Daiki Kobayashi
BACKGROUND: The aim of this study was to evaluate the prediction factors for perforated peptic ulcer (PPU). METHODS: At St. Luke's International Hospital in Tokyo, Japan, a case control study was performed between August 2004 and March 2016. All patients diagnosed with PPU were included. As control subjects, patients with age, sex and date of CT scan corresponding to those of the PPU subjects were included in the study at a proportion of 2 controls for every PPU subject...
February 15, 2018: BMC Gastroenterology
https://www.readbyqxmd.com/read/29366313/laparoscopic-repair-of-perforated-peptic-ulcer
#9
Flore Varcus, Ion Paun, Ciprian Duta, Amadeus Dobrescu, Mirela Frandes, Cristi Tarta
INTRODUCTION: Perforations of the peptic ulcers (PPUs) are the most common cause of emergency surgery among the complications of the gastroduodenal ulcers and the leading cause for morbidity and mortality due to secondary peritonitis and sepsis. PPU is a condition in which laparoscopic perforation repair (LPR) is an optimal solution. It makes possible the identification of the perforation's site and allows closure of the perforation and the subsequent peritoneal lavage, as in an open repair (OR) but without the large upper mid-abdominal incision...
April 2018: Minerva Chirurgica
https://www.readbyqxmd.com/read/29354867/short-and-long-term-outcomes-of-surgical-management-of-peptic-ulcer-complications-in-the-era-of-proton-pump-inhibitors
#10
Rabea Hasadia, Yael Kopelman, Oded Olsha, Ricardo Alfici, Itamar Ashkenazi
PURPOSE: We evaluated the short-term and long-term outcomes of emergency operations for peptic ulcer (PUD) complications in a period of time in which the need for surgery is infrequent. METHODS: Retrospective review of operated patients (2007-2015) in one medical center. RESULTS: 81 patients were included (8.9 patients/year): 70 (86.4%) male; 11 (13.6%) female. Indications for operation were hemorrhage in 18 (22.2%), perforation in 62 (76...
January 22, 2018: European Journal of Trauma and Emergency Surgery: Official Publication of the European Trauma Society
https://www.readbyqxmd.com/read/29260131/is-it-possible-to-reduce-the-surgical-mortality-and-morbidity-of-peptic-ulcer-perforations
#11
Adnan Hut, Cihad Tatar, Doğan Yıldırım, Turgut Dönmez, Akın Ünal, Ahmet Kocakuşak, Muzaffer Akıncı
Objective: Peptic ulcer perforation is a life-threatening situation requiring urgent surgical treatment. A novel vision in peptic ulcer perforation is necessary to fill the gaps created by antiulcer medication, aging of the patients, and presentation of resistant cases in our era. In this study, we aimed to share our findings regarding the effects of various risk factors and operative techniques on the mortality and morbidity of patients with peptic ulcer perforation. Material and Methods: Data from 112 patients presenting at our Training and Research Hospital Emergency Surgery Department between January 2010 and December 2015 who were diagnosed with PUP through physical examination and laboratory and radiological tests and operated at the hospital have been retrospectively analyzed...
2017: Turkish Journal of Surgery
https://www.readbyqxmd.com/read/29180201/laparoscopic-repair-of-perforated-peptic-ulcer-simple-closure-versus-omentopexy
#12
COMPARATIVE STUDY
Being-Chuan Lin, Chien-Hung Liao, Shang-Yu Wang, Tsann-Long Hwang
BACKGROUND: This report presents our experience with laparoscopic repair performed in 118 consecutive patients diagnosed with a perforated peptic ulcer (PPU). We compared the surgical outcome of simple closure with modified Cellan-Jones omentopexy and report the safety and benefit of simple closure. METHODS: From January 2010 to December 2014, 118 patients with PPU underwent laparoscopic repair with simple closure (n = 27) or omentopexy (n = 91). Charts were retrospectively reviewed for demographic characteristics and outcome...
December 2017: Journal of Surgical Research
https://www.readbyqxmd.com/read/29155448/influence-of-national-centralization-of-oesophagogastric-cancer-on-management-and-clinical-outcome-from-emergency-upper-gastrointestinal-conditions
#13
S R Markar, H Mackenzie, T Wiggins, A Askari, A Karthikesalingam, O Faiz, S M Griffin, J D Birkmeyer, G B Hanna
BACKGROUND: In England in 2001 oesophagogastric cancer surgery was centralized. The aim of this study was to evaluate whether centralization of oesophagogastric cancer to high-volume centres has had an effect on mortality from different emergency upper gastrointestinal conditions. METHODS: The Hospital Episode Statistics database was used to identify patients admitted to hospitals in England (1997-2012). The influence of oesophagogastric high-volume cancer centre status (20 or more resections per year) on 30- and 90-day mortality from oesophageal perforation, paraoesophageal hernia and perforated peptic ulcer was analysed...
January 2018: British Journal of Surgery
https://www.readbyqxmd.com/read/29142512/non-steroidal-anti-inflammatory-drug-induced-enteropathy
#14
REVIEW
Sung Jae Shin, Choong-Kyun Noh, Sun Gyo Lim, Kee Myung Lee, Kwang Jae Lee
Non-steroidal anti-inflammatory drugs (NSAIDs) are well known to be associated with serious upper gastrointestinal complications, such as peptic ulcer, bleeding, perforation, and obstruction. Recently, attention has been mainly focused on the small bowel injuries caused by NSAIDs, and new endoscopic techniques such as capsule endoscopy and double balloon endoscopy can help in detecting such injuries. This article reviewed the epidemiology, pathogenesis, clinical manifestations, diagnosis, and treatment of small bowel injuries caused by NSAIDs...
October 2017: Intestinal Research
https://www.readbyqxmd.com/read/29064799/gastroesophageal-reflux-disease-the-results-of-videolaparoscopic-fundoplication-at-five-years-after-surgery
#15
Andriy R Stasyshyn
INTRODUCTION: GERD reduces social activity and significantly affects the quality of life (QOL) of patients and the risk of complications (cancer of the esophagus, esophageal-gastric bleeding, strictures, perforation) is one of the most pressing problems of medicine of XXI century. The aim of the research is to evaluate the results of videolaparoscopic fundoplication at five years after surgery in patients with gastroesophageal reflux disease. MATERIAL AND METHODS: We studied results of videolaparoscopic antireflux surgery (VLAS) during 2009-2016 years in Department of Surgery and Endoscopy Faculty of postgraduate medical education Lviv National Medical University...
2017: Wiadomości Lekarskie: Organ Polskiego Towarzystwa Lekarskiego
https://www.readbyqxmd.com/read/29062455/laparoscopic-pyloroplasty-for-perforated-peptic-ulcer
#16
Edvard Grišin, Saulius Mikalauskas, Tomas Poškus, Valdemaras Jotautas, Kęstutis Strupas
Peptic ulcer is a common disease affecting millions of people every year. Despite improved understanding and treatment of the disease, the number of patients admitted with duodenal peptic ulcer perforation has not decreased. Deaths from peptic ulcer disease overcome other common emergency situations. Laparoscopic repair of the perforated peptic ulcer (PPU) is the gold standard approach for simple perforation. However, in patients with large perforated chronic ulcers laparotomy with pyloroplasty is the standard treatment...
September 2017: Wideochirurgia i Inne Techniki Mało Inwazyjne, Videosurgery and Other Miniinvasive Techniques
https://www.readbyqxmd.com/read/29033302/antimicrobial-susceptibility-of-helicobacter-pylori-strains-isolated-from-children-in-israel
#17
Nina Pastukh, Avi Peretz, Diana Brodsky, Natlya Isakovich, Maya Azrad, Avi On
OBJECTIVES: Helicobacter pylori is a bacterial pathogen causing inflammation of the gastric mucosa that may lead to peptic ulcer, perforation or malignancy. Children are at risk of contracting H. pylori and developing subsequent morbidity. Diagnosis and management in children are difficult and merit a different approach compared with adults. This study aimed to describe the antimicrobial resistance rates of H. pylori to amoxicillin, tetracycline, clarithromycin, metronidazole, levofloxacin and rifampicin...
March 2018: Journal of Global Antimicrobial Resistance
https://www.readbyqxmd.com/read/28920145/impact-of-drain-insertion-after-perforated-peptic-ulcer-repair-in-a-japanese-nationwide-database-analysis
#18
K Okumura, K Hida, S Kunisawa, T Nishigori, H Hosogi, Y Sakai, Y Imanaka
BACKGROUND: Many perforated peptic ulcers (PPUs) require surgical repair due to diffuse peritonitis. However, few studies have examined the clinical effects of postoperative drainage after PPU repair. This study aimed to investigate the drain insertion rates in patients who underwent PPU repair in Japan, and to clarify the impact of drain insertion on the postoperative clinical course. METHODS: A retrospective nationwide cohort study was performed using administrative claims data of patients who had undergone PPU repair between 2010 and 2016...
March 2018: World Journal of Surgery
https://www.readbyqxmd.com/read/28738919/laparoscopic-approach-to-perforated-peptic-ulcers-trends-toward-quicker-recovery
#19
Salim Hosein, Jeffrey C Lawrence, George M Fuhrman, William S Richardson
No abstract text is available yet for this article.
July 1, 2017: American Surgeon
https://www.readbyqxmd.com/read/28726018/association-of-vagotomy-and-decreased-risk-of-subsequent-ischemic-stroke-in-complicated-peptic-ulcer-patients-an-asian-population-study
#20
Chu-Wen Fang, Chun-Hung Tseng, Shih-Chi Wu, William Tzu-Liang Chen, Chih-Hsin Muo
OBJECTIVES: The primary management of peptic ulcers is medical treatment. Persistent exacerbation of a peptic ulcer may lead to complications (perforation and/or bleeding). There has been a trend toward the use of a less invasive surgical simple suture, simple local suture or non-operative (endoscopic/angiography) hemostasis rather than acid-reducing vagotomy (i.e., vagus nerve severance) for treating complicated peptic ulcers. Other studies have shown the relationship between high vagus nerve activity and survival in cancer patients via reduced levels of inflammation, indicating the essential role of the vagus nerve...
December 2017: World Journal of Surgery
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