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liver transplantation surgical technique

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https://www.readbyqxmd.com/read/29773779/prospects-for-us-cuba-cooperation-in-gastroenterology-hepatology-and-liver-transplantation
#1
Marlen I Castellanos-Fernández, Mirtha Infante-Velázquez, Enrique Arús-Soler, Marcelo Kugelmas, Ramón Bataller, Ramón Villamil-Martínez, Zaily Dorta-Guridi, Caridad Ruenes-Domenech
Gastroenterology, hepatology and liver transplant exchanges between the USA and Cuba have mainly consisted of scientific events and short visits. This has facilitated Cuba's inclusion in recognized scientific organizations, familiarity with Cuba's biotech products for treatment of liver disease, and access by Cuban professionals to the highest level of scientific information for clinical practice. It has also given health professionals in the US a more accurate picture of Cuba's health sector. The results of the Global Alcoholic Liver Disease Survey, which included Cuba and was designed and coordinated in the USA, opened doors to joint research and scientific publications...
April 2018: MEDICC Review
https://www.readbyqxmd.com/read/29751198/price-to-pay-portal-vein-arterialization-for-hepatic-artery-thrombosis-after-living-donor-liver-transplantation-a-case-report
#2
Worakitti Lapisatepun, Anon Chotirosniramit, Trichak Sandhu, Kanya Udomsin, Wasana Ko-Iam, Phuriphong Chanthima, Warangkana Lapisatepun, Settapong Boonsri, Suraphong Lorsomradee, Quanhathai Kaewpoowat, Sunhawit Junrungsee
OBJECTIVE: Hepatic artery thrombosis (HAT) is one of the most serious complications of liver transplantation that can potentially lead to loss of the allograft. Retransplantation is the only option when revascularization can't be performed but the donor may be not available in the short period of time. We report the technique of using portal vein arterialization (PVA) for bridging before retransplantation. There are few reports in living donor setting. CASE DESCRIPTION: The recipient of the liver was a 59 year old male who received an extended right lobe graft from his son...
May 2, 2018: International Journal of Surgery Case Reports
https://www.readbyqxmd.com/read/29704975/1000-consecutive-liver-transplants-descriptive-analysis-and-evolution-of-a-single-center
#3
José Tinoco González, Jose María Álamo Martínez, Carmen Bernal Bellido, Gonzalo Suárez Artacho, Luis Miguel Marín Gómez, Lydia Barrera-Pulido, Javier Padillo Ruíz, Miguel Ángel Gómez Bravo
Between 1991 and 2013, 1,000 liver transplantations were performed at Virgen del Rocio Hospital (Seville, Spain). A retrospective study was conducted, analyzing the characteristics of recipients and donors, indications, surgical technique, complications and survival in 2 different stages (1991-2002 vs. 2003-2013) coinciding with the implementation of the MELD scale as a prioritization model. The most frequent indication were of hepatopathy of hepatocellular origin in 48.8%. There was a significant increase in the indications for hepatocarcinoma (8...
April 25, 2018: Cirugía Española
https://www.readbyqxmd.com/read/29701490/influence-of-gut-microbiota-and-intestinal-barrier-on-enterogenic-infection-after-liver-transplantation
#4
Jingzhou Mu, Qiuyu Chen, Liang Zhu, Yunhong Wu, Suping Liu, Yufei Zhao, Tonghui Ma
Liver transplantation is currently a standard therapy for patients with end-stage liver diseases and hepatocellular carcinoma. Given that liver transplantation has undergone a thriving development in these decades, the survival rates after liver transplantation have markedly improved as a result of the critical advancement in surgical techniques, immunosuppressive therapies, and postoperative care. However, infection remains a fatal complication after liver transplantation surgery. In particular, enterogenic infection represents a major complication in liver transplant recipients...
April 27, 2018: Current Medical Research and Opinion
https://www.readbyqxmd.com/read/29684001/one-hundred-and-fifteen-cases-of-pure-laparoscopic-living-donor-right-hepatectomy-at-a-single-center
#5
Kwang-Woong Lee, Suk Kyun Hong, Kyung-Suk Suh, Hyo-Sin Kim, Sung-Woo Ahn, Kyung Chul Yoon, Jeong-Moo Lee, Jae-Hyung Cho, Hyeyoung Kim, Nam-Joon Yi
BACKGROUND: The pure laparoscopic approach to donor hepatectomy is being taken more often. However, few centers perform pure laparoscopic donor right hepatectomy (PLDRH) because it requires a high level of surgical skill. Studies reporting initial outcomes of PLDRH may prompt further implementation of the technique and help reduce initial learning curves at other transplant centers. This study reports performance of PLDRH at a single center with extensive experience of adult living donor liver transplantation...
April 21, 2018: Transplantation
https://www.readbyqxmd.com/read/29683437/re-arterialized-rat-partial-liver-transplantation-with-an-in-vivo-vessel-oriented-70-hepatectomy
#6
Xuehai Chen, Rong Yu, Ziqiang Xu, Yan Zhang, Chengyang Liu, Bicheng Chen, Hao Jin
Split liver transplantation and living liver donor liver transplantation were developed in the clinic to utilize liver organs in a more efficient manner. To better understand the mechanism behind these surgical procedures, a rat partial liver transplantation (PLTx) model was established for relevant surgical studies. Because of the complexity of the rat PLTx model, a protocol with detailed descriptions is required. An article published previously reported a protocol in which ex vivo hepatectomy was used to achieve 50% rat PLTx...
April 8, 2018: Journal of Visualized Experiments: JoVE
https://www.readbyqxmd.com/read/29661465/allograft-portacaval-shunt-in-small-for-size-liver-in-deceased-donor-liver-transplant
#7
J H Nguyen, D M Harnois
Portal hyperperfusion is detrimental to small-for-size livers (SFSLs) in liver transplantation. Surgical techniques modulating portal inflow provide the most effective approach to protect the SFSL. In this report, we describe a technique creating an allograft portacaval shunt that effectively attenuates portal inflow without a requirement of extensive surgical dissection in the recipient during the transplantation.
April 2018: Transplantation Proceedings
https://www.readbyqxmd.com/read/29629319/liver-transplantation-for-unresectable-pancreatic-neuroendocrine-tumors-with-liver-metastases-in-an-era-of-transplant-oncology
#8
REVIEW
Keita Shimata, Yasuhiko Sugawara, Taizo Hibi
Patients with pancreatic neuroendocrine tumors (pNETs) very often present with a metastatic disease at the first diagnosis. Liver transplantation (LT) for unresectable pNET with liver metastases (pNETLM) has been described to prolong survival in highly selected patients, although outcomes were worse than those of patients who underwent LT for gastrointestinal NETLM (GI-NETLM). In this review, several proposed criteria are described with their rationale and controversies. Most of the data used to establish these criteria do not reflect the recent improvements of non-surgical treatments that has changed the landscape of treatment for pNETs, including the development of peptide receptor radionuclide therapy and molecular-targeted agents (sunitinib and everolimus)...
February 2018: Gland Surgery
https://www.readbyqxmd.com/read/29623266/the-potential-role-of-liver-transplantation-as-a-treatment-option-in-colorectal-liver-metastases
#9
REVIEW
Pål-Dag Line, Morten Hagness, Svein Dueland
Liver resection is the only potentially curative treatment option in patients with liver metastases from colorectal cancer, but only about 20% of the patients are resectable. Liver transplantation of patients with unresectable liver metastases was attempted in the early era but it was abandoned due to poor survival. During the last decade, several case reports, a controlled pilot study, and a retrospective cohort study indicated that prolonged disease-free survival and overall survival can be obtained in a proportion of these patients...
2018: Canadian Journal of Gastroenterology & Hepatology
https://www.readbyqxmd.com/read/29604232/clinical-course-of-hepatic-artery-thrombosis-after-living-donor-liver-transplantation-using-the-right-lobe
#10
Ho Joong Choi, Dong Goo Kim, Yumi Kim, Bong Jun Kwak, Jae Hyun Han, Tae Ho Hong, Young Kyoung You
Background Hepatic artery thrombosis (HAT) can result in biliary tree necrosis and graft loss necessitating re-transplantation. The most effective treatment approach is still controversial. This study was performed to review the outcomes of HAT after living donor liver transplantation (LDLT), and to clarify the feasibility of different strategies. Methods From May 1996 to August 2017, LDLT using the right lobe was performed in 827 adult patients in our center. Our technique of hepatic artery (HA) reconstruction is end-to-end anastomosis under a microscope (× 10)...
March 31, 2018: Liver Transplantation
https://www.readbyqxmd.com/read/29595013/-multidisciplinary-management-of-alveolar-echinococcosis-echino-liege-working-group
#11
A Cambier, J B Giot, P Leonard, N Bletard, P Meunier, R Hustinx, J Delwaide, N Meurisse, P Honore, B Losson, M P Hayette, O Detry
Alveolar echinococcosis is a zoonotic disease due to the tapeworm Echinococcus multilocularis. The definitive host is the red fox. Until recently, Belgium was considered a country at very low risk for alveolar echinococcosis. However, recent studies carried out in southern Belgium have revealed, through post-mortem examination, high prevalences (up to 62 %) in foxes. Cats and dogs can act as definitive hosts. Human are accidentally infected by ingestion of food contaminated by the feces. After a long incubation period, invasive hepatic lesions may appear, as well as extra-hepatic lesions...
March 2018: Revue Médicale de Liège
https://www.readbyqxmd.com/read/29593928/extra-anatomic-jump-graft-from-the-right-colic-vein-a-novel-technique-to-manage-portal-vein-thrombosis-in-liver-transplantation
#12
Paolo Magistri, Giuseppe Tarantino, Tiziana Olivieri, Annarita Pecchi, Roberto Ballarin, Fabrizio Di Benedetto
Background: In the context of cirrhosis, portal vein thrombosis (PVT) is present in 2.1% to 26% of patients. PVT is no longer considered an absolute contraindication for liver transplantation, and nowadays, surgical strategies depend on the extent of PVT. Complete PVT is associated with higher morbidity rates and poor prognosis, while comparable long-term outcomes can be achieved as long as physiological portal inflow is restored. Materials and Methods: We report our experience with a 45-year-old patient undergoing liver transplant with a PVT (stage III-b)...
2018: Case Reports in Surgery
https://www.readbyqxmd.com/read/29579864/outcomes-of-liver-transplantation-using-older-donors-after-circulatory-death-and-the-super-rapid-technique-14-cases
#13
P Ramirez, D Ferreras, B Febrero, M Royo, P Cascales, J M Rodriguez, A Rios, J A Fernandez, M R González, F Sanchez-Bueno, R Robles, P Parrilla
INTRODUCTION: Donation after circulatory death (DCD) has increased in the last decade, although a slight increase in surgical complications has been reported in liver transplantation (LT). Therefore, DCD is not recommended with donors aged 60 years or more because it entails an added risk. However, donation after brain death (DBD)-LT with donors aged 70 years or more shows acceptable results. OBJECTIVE: The objective was to analyze the characteristics and complications of DCD-LT with donors aged 70 years or more (DCD-70)...
March 2018: Transplantation Proceedings
https://www.readbyqxmd.com/read/29520204/laparoscopic-parenchyma-sparing-liver-resection-for-colorectal-metastases
#14
Davit L Aghayan, Egidijus Pelanis, Åsmund Avdem Fretland, Airazat M Kazaryan, Mushegh A Sahakyan, Bård I Røsok, Leonid Barkhatov, Bjørn Atle Bjørnbeth, Ole Jakob Elle, Bjørn Edwin
Background: Laparoscopic liver resection (LLR) of colorectal liver metastases (CLM) is increasingly performed in specialized centers. While there is a trend towards a parenchyma-sparing strategy in multimodal treatment for CLM, its role is yet unclear. In this study we present short- and long-term outcomes of laparoscopic parenchyma-sparing liver resection (LPSLR) at a single center. Patients and methods: LLR were performed in 951 procedures between August 1998 and March 2017 at Oslo University Hospital, Oslo, Norway...
March 2018: Radiology and Oncology
https://www.readbyqxmd.com/read/29518665/sharp-liver-excision-under-hepatic-vascular-exclusion-in-case-of-liver-transplant-for-large-polycystic-disease-case-report-of-a-new-surgical-technique
#15
Filip Thieme, Jiri Fronek
INTRODUCTION: Polycystic liver disease is observed in 75-90% of patients with autosomal dominant polycystic kidney disease (ADPKD). ADPKD has a high prevalence of 1/1000. Hepatomegaly severely reduces quality of life and liver transplantation seems to be method of choice for many patients. Because of the rarity of this disease and the small number of symptomatic patients with massive hepatomegaly indicated for the transplantation, there is no standard approach for explantation of the liver...
2018: International Journal of Surgery Case Reports
https://www.readbyqxmd.com/read/29491050/update-on-surgical-management-of-small-bowel-neuroendocrine-tumors
#16
REVIEW
Demetrios Moris, Ioannis Ntanasis-Stathopoulos, Diamantis I Tsilimigras, Stylianos Vagios, Andreas Karamitros, Georgios Karaolanis, John Griniatsos, Alexandros Papalampros, Ioannis Papaconstantinou, Georgios K Glantzounis, Eleftherios Spartalis, Dan G Blazer, Evangelos Felekouras
The widespread use of endoscopy and imaging in combination with the continuous update of the staging systems for neuroendocrine tumors has led to an increase in the incidence of small intestinal neuroendocrine tumors (si-NENs) globally. Despite high survival rates, severe complications may occur even in early stages due to the anatomic location of the primary site and the desmoplastic reaction. Surgery plays a central role in the management of patients with si-NENs. Excision of locoregional disease along with extensive lymph node dissection should be performed in fit patients, even in the presence of metastases...
March 2018: Anticancer Research
https://www.readbyqxmd.com/read/29485511/small-for-size-syndrome-does-not-occur-in-intestinal-transplantation-without-liver-containing-grafts
#17
Jang I Moon, Thomas D Schiano, Alyssa Burnham, Kwai Lam, Kishore R Iyer
BACKGROUND: The ideal donor in intestinal transplantation is generally considered to be 50 - 70% of recipient body weight. This may be due to concerns for "small for size" syndrome as seen in liver transplantation. We report our experience using smaller donors (donor-recipient weight ratio, DRWR < 50%) in intestinal transplantation (ITX) recipients. METHODS: We studied a group of ITX recipients with DRWR ≤ 50% to unmatched controls who received intestinal allografts with DRWR > 50%...
February 26, 2018: Transplantation
https://www.readbyqxmd.com/read/29465439/intestinal-re-transplantation-indications-techniques-and-outcomes
#18
Armando Ganoza, Neslihan Celik, George V Mazariegos
PURPOSE OF REVIEW: The field of intestinal transplantation has shown significant growth and has become the gold standard therapy for patients that suffer from the complications of total parenteral nutrition due to irreversible intestinal failure. In the early years of intestinal transplant, retransplantation was associated with extremely high morbidity and mortality. The purpose of this review is to summarize recent encouraging reports, showing significant improvement in outcomes after intestinal retransplantation...
April 2018: Current Opinion in Organ Transplantation
https://www.readbyqxmd.com/read/29424768/current-status-of-surgical-incisions-used-in-donors-during-living-related-liver-transplantation-a-nationwide-survey-in-japan
#19
Ken Shirabe, Susumu Eguchi, Hideaki Okajima, Kiyoshi Hasegawa, Shigeru Marubashi, Koji Umeshita, Seiji Kawasaki, Katsuhiko Yanaga, Mitsuo Shimada, Toshimi Kaido, Naoki Kawagishi, Akinobu Taketomi, Koichi Mizuta, Norihiro Kokudo, Shinji Uemoto, Yoshihiko Maehara
BACKGROUND: Smaller surgical incisions have recently been introduced in living donor liver procurement. This study used national data from Japan to clarify the present status of surgical incisions in living donor liver procurement. METHODS: A nationwide, questionnaire-based survey related to 3121 donors and recipients was used. Donors were divided into two groups: left lateral segment graft (LLSG) procurement (n=690) and other types (n=2431). Incisions were classified into six types: type I, upper midline and bilateral subcostal; type II, upper midline and right subcostal; type III: upper midline and right subcostal to the right lateral margin of the abdominal rectus muscle; type IV, upper midline without laparoscopy; type V, upper midline with laparoscopy; and type VI, lower abdominal using the full laparoscopic technique...
February 9, 2018: Transplantation
https://www.readbyqxmd.com/read/29399525/transplant-artery-thrombosis-and-outcomes
#20
REVIEW
Mark D Sugi, Hassan Albadawi, Grace Knuttinen, Sailendra G Naidu, Amit K Mathur, Adyr A Moss, Rahmi Oklu
Post-transplantation allograft arterial thrombosis is a well-recognized complication associated with solid organ transplantation. Much of the literature is centered on liver and kidney transplantation, which will therefore serve as the principle basis for this review, with a brief discussion on pancreas transplantation and associated arterial complications. The number of solid organ transplants has been steadily increasing over the past decade in parallel with growing demand for organs and expansion of the transplantation criteria for both donors and recipients...
December 2017: Cardiovascular Diagnosis and Therapy
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