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https://www.readbyqxmd.com/read/29433062/suppression-of-the-vestibular-short-latency-evoked-potential-by-electrical-stimulation-of-the-central-vestibular-system
#1
Christopher J Pastras, Ian S Curthoys, Ljiljana Sokolic, Daniel J Brown
In an attempt to view the effects of the efferent vestibular system (EVS) on peripheral dynamic vestibular function, we have monitored the Vestibular short-latency Evoked Potential (VsEP) evoked by pulses of bone conducted vibration during electrical stimulation of the EVS neurons near the floor of the fourth ventricle in the brainstem of anesthetized guinea pigs. Given the reported effects of EVS on primary afferent activity, we hypothesized that EVS stimulation would cause a slight reduction in the VsEP amplitude...
February 2, 2018: Hearing Research
https://www.readbyqxmd.com/read/29408247/peratrial-device-closure-of-different-locations-of-mitral-paravalvular-leaks
#2
Li Hongxin, Guo Wenbin, Hai-Zhou Zhang, Fei Liang, Gui-Dao Yuan, Zeeshan Farhaj, Jun Zhang
BACKGROUND: The current approaches of transcatheter closure of mitral paravalvular leak (MPVL) have different drawbacks. The challenges come from transseptal puncture, accessing the MPVL site, and the absence of dedicated delivery systems. This study introduces a novel peratrial approach for device closure of different locations of MPVLs using a probe-assisted delivery system under three-dimensional transesophageal echocardiography. METHODS: A 4.0 cm minithoracotomy incision was made in the fourth right interspaces...
February 2, 2018: Annals of Thoracic Surgery
https://www.readbyqxmd.com/read/29379237/intracranial-translucency-as-a-sonographic-marker-for-detecting-open-spina-bifida-at-11-13-6-weeks-scan-our-experience
#3
Madhavi L Teegala, Dhamangaonkar G Vinayak
Aims and Objectives: The fourth ventricle, seen as intracranial translucency (IT) at 11-13+6 weeks, has been reported to be obliterated in cases of open spina bifida (OSB). Our aim was to assess its role in detecting OSB at 11-13+6 weeks. Materials and Methods: This prospective study was conducted at foetal medicine unit from January 2014 to June 2015. All women who underwent both first and mid-trimester scan in our unit were included in the study. IT was categorized as normal, obliterated or not clear...
October 2017: Indian Journal of Radiology & Imaging
https://www.readbyqxmd.com/read/29373484/mechanisms-of-cardiovascular-protection-associated-with-intermittent-hypobaric-hypoxia-exposure-in-a-rat-model-role-of-oxidative-stress
#4
Miguel Aguilar, Alejandro González-Candia, Jorge Rodríguez, Catalina Carrasco-Pozo, Daniel Cañas, Claudio García-Herrera, Emilio A Herrera, Rodrigo L Castillo
More than 140 million people live and works (in a chronic or intermittent form) above 2500 m worldwide and 35 million live in the Andean Mountains. Furthermore, in Chile, it is estimated that 55,000 persons work in high altitude shifts, where stays at lowlands and interspersed with working stays at highlands. Acute exposure to high altitude has been shown to induce oxidative stress in healthy human lowlanders, due to an increase in free radical formation and a decrease in antioxidant capacity. However, in animal models, intermittent hypoxia (IH) induce preconditioning, like responses and cardioprotection...
January 26, 2018: International Journal of Molecular Sciences
https://www.readbyqxmd.com/read/29367374/intracranial-myopericytoma-a-tumour-in-a-rare-location
#5
Rui Caetano Oliveira, Ricardo Velasco, Gonçalo Roque Santos, Olinda Rebelo
A 49-year-old female with history of headache, nausea and vomiting with some weeks of evolution, without neurological symptoms. Radiology revealed an expansive lesion near the inferior vermix and cerebellar tonsils, with heterogeneous gadolinium uptake and mass effect on the fourth ventricle, representing a probable extraventricular origin for the lesion. Pathological examination showed a proliferation of oval/spindle cell proliferation with eosinophil cytoplasm and small and monotonous nuclei, without mitoses...
January 23, 2018: BMJ Case Reports
https://www.readbyqxmd.com/read/29351420/fourth-ventricular-tsh-induces-satiety-and-increases-body-temperature-in-rats
#6
Ulrika Smedh, Karen A Scott, Timothy H Moran
Besides its well-known action to stimulate thyroid hormone release, Thyrotropin mRNA is expressed within the brain and Thyrotropin and its receptor have been shown to be present in brain areas that control feeding and gastrointestinal function. Here, the hypothesis that Thyrotropin acts on receptors in the dorsal hindbrain to alter food intake and/or gastric function was tested. Fourth ventricular injections of Thyrotropin (0.06, 0.6 and 6.0 µg) were given to rats with chronic intracerebroventricular cannulas aimed at the fourth ventricle...
January 3, 2018: American Journal of Physiology. Regulatory, Integrative and Comparative Physiology
https://www.readbyqxmd.com/read/29339320/primary-obstruction-of-the-foramen-of-luschka-anatomy-histology-and-clinical-significance
#7
Laszlo Barany, Gabor Baksa, Patonay Lajos, Gergely Racz, Oliver Ganslandt, Michael Buchfelder, Peter Kurucz
BACKGROUND: The foramen of Luschka is a natural aperture between the fourth ventricle and the subarachnoid space at the cerebellopontine angle (CPA). Membranous closure of this foramen is referred to as primary obstruction. The available information about this variant and its role in the development of the cysts of the posterior fossa are contradictory in the literature. METHODS: Sixty-one formalin-fixed human brains (122 foramina) were involved in this study. Both the macroscopic and the histological features of the obstructed foramina were examined...
January 12, 2018: World Neurosurgery
https://www.readbyqxmd.com/read/29339161/a-new-genetically-engineered-mouse-model-of-choroid-plexus-carcinoma
#8
Salsabiel El Nagar, Frederique Zindy, Charlotte Moens, Luc Martin, Damien Plassard, Martine F Roussel, Thomas Lamonerie, Nathalie Billon
Choroid plexus carcinomas (CPCs) are highly malignant brain tumours predominantly found in children and associated to poor prognosis. Improved therapy for these cancers would benefit from the generation of animal models. Here we have created a novel mouse CPC model by expressing a stabilised form of c-Myc (MycT58A) and inactivating Trp53 in the choroid plexus of newborn mice. This induced aberrant proliferation of choroid plexus epithelial cells, leading to aggressive tumour development and death within 150 days...
January 12, 2018: Biochemical and Biophysical Research Communications
https://www.readbyqxmd.com/read/29338911/-rosette-forming-glioneuronal-tumor-of-the-fourth-ventricle-two-cases-report-and-literature-review
#9
Bernardino Choque Cuba, José Manuel Ortega Zufiría, Pedro Domingo Poveda Núñez, Noemí Lomillos Prieto, Mario Sierra Rodríguez, Martin Tamarit Degenhardt, Remedios López Serrano, Juan Carlos Gómez Angulo Giner, José Antonio Aramburu González
Rosette-forming glioneuronal tumor of the fourth ventricle is a primary central nervous system tumor introduced in the group of glioneuronal tumors in the WHO classification of 2007. Initially it was described around the fourth ventricle, but recently have been published cases in different locations. We present 2cases of this rare tumor, both surgically treated. The first in a 41 year old man with typical symptoms of posterior fossa injury. The second in an 18 year old woman, with incidental finding of posterior fossa injury that was also surgically treated...
January 12, 2018: Neurocirugía
https://www.readbyqxmd.com/read/29327996/letter-to-the-editor-tumors-of-the-fourth-ventricle
#10
Chiazor U Onyia
No abstract text is available yet for this article.
January 12, 2018: Journal of Neurosurgery
https://www.readbyqxmd.com/read/29315657/dysautonomy-in-different-death-risk-groups-rassi-score-in-patients-with-chagas-heart-disease
#11
Catherine Masiel Merejo Peña, Michel Silva Reis, Basílio de Bragança Pereira, Emília Matos do Nascimento, Roberto Coury Pedrosa
BACKGROUND: It has been difficult to prove that "catecholamine-induced cardiomyopathy" contributes to the mechanism of sudden cardiac death in Chagas heart disease. Also, it is almost impossible to rule out the possibility that it is not involved in the process. More importantly, the vagal-cholinergic pathway in the ventricle plays a direct role in the prevention of the initiation of complex ventricular arrhythmias, including nonsustained ventricular tachycardia, ventricular fibrillation responsible for sudden death...
January 5, 2018: Pacing and Clinical Electrophysiology: PACE
https://www.readbyqxmd.com/read/29312599/histopathological-molecular-clinical-and-radiological-characterization-of-rosette-forming-glioneuronal-tumor-in-the-central-nervous-system
#12
Chenlong Yang, Jingyi Fang, Guang Li, Shaowu Li, Tingting Ha, Jiangfei Wang, Bao Yang, Jun Yang, Yulun Xu
Objective: A rosette-forming glioneuronal tumor (RGNT) is a rare entity originally described in the fourth ventricle. Recently, RGNTs occurring in extraventricular sites and those with malignant behaviors have been reported. The purpose of this study was to analyze the clinicoradiological and histopathological features, therapeutic strategies, and outcomes of RGNTs. Methods: We enrolled 38 patients diagnosed with RGNTs pathologically between August 2009 and June 2016...
December 12, 2017: Oncotarget
https://www.readbyqxmd.com/read/29307024/predictors-of-ventricular-tension-pneumocephalus-after-posterior-fossa-surgery-in-the-sitting-position
#13
Alexandra Sachkova, Timm Schemmerling, Maria Goldberg, Volodymyr Solomiichuk, Veit Rohde, Kajetan L von Eckardstein, Bawarjan Schatlo
BACKGROUND: Ventricular pneumocephalus is a rare but potentially life-threatening complication of cranial surgery in the sitting position. OBJECTIVE: The objective of the study is to assess the incidence and risk factors of postoperative ventricular pneumocephalus. METHODS: We performed a retrospective chart review of 307 consecutive patients (147 men, 160 women) treated at our institution by intracranial surgery in the sitting position from January 2010 to October 2014...
January 6, 2018: Acta Neurochirurgica
https://www.readbyqxmd.com/read/29301040/where-and-when-to-cut-fluorescein-guidance-for-brain-stem-and-spinal-cord-tumor-surgery-technical-note
#14
Eric Suero Molina, Walter Stummer
BACKGROUND: Spinal cord and brain stem lesions require a judicious approach with an optimized trajectory due to a clustering of functions on their surfaces. Intraoperative mapping helps locate function. To confidently locate such lesions, neuronavigation alone lacks the desired accuracy and is of limited use in the spinal cord. OBJECTIVE: To evaluate the clinical value of fluoresceins for initial delineation of such critically located lesions. METHODS: We evaluated fluorescein guidance in the surgical resection of lesions with blood-brain barrier disruption demonstrating contrast enhancement in magnet resonance imaging in the spinal cord and in the brain stem in 3 different patients...
December 29, 2017: Operative Neurosurgery (Hagerstown, Md.)
https://www.readbyqxmd.com/read/29288111/cystic-cavernoma-of-the-fourth-ventricle-in-a-paediatric-patient
#15
Jared Yeo, Kenneth Chang, Lee Ping Ng, Wan Tew Seow, David Low, Sharon Yy Low
No abstract text is available yet for this article.
December 26, 2017: World Neurosurgery
https://www.readbyqxmd.com/read/29282698/elevated-surfactant-protein-levels-and-increased-flow-of-cerebrospinal-fluid-in-cranial-magnetic-resonance-imaging
#16
Stefan Schob, Alexander Weiß, Alexey Surov, Julia Dieckow, Cindy Richter, Mandy Pirlich, Diana Horvath-Rizea, Wolfgang Härtig, Karl-Titus Hoffmann, Matthias Krause, Ulf Quäschling
Surfactant proteins (SPs) are a multifunctional group of proteins, responsible for the regulation of rheological properties of body fluids, host defense, and cellular waste clearance. Their concentrations are changed in cerebrospinal fluid (CSF) of patients suffering from communicating hydrocephalus. Hydrocephalic conditions are accompanied by altered CSF flow dynamics; however, the association of CSF-SP concentrations and CSF flow has not yet been investigated. Hence, the aim of this study was to evaluate the association between SP concentrations in the CSF and marked CSF flow phenomena at different anatomical landmarks of CSF spaces...
December 27, 2017: Molecular Neurobiology
https://www.readbyqxmd.com/read/29280147/the-origins-of-the-circumventricular-organs
#17
REVIEW
Clemens Kiecker
The circumventricular organs (CVOs) are specialised neuroepithelial structures found in the midline of the brain, grouped around the third and fourth ventricles. They mediate the communication between the brain and the periphery by performing sensory and secretory roles, facilitated by increased vascularisation and the absence of a blood-brain barrier. Surprisingly little is known about the origins of the CVOs (both developmental and evolutionary), but their functional and organisational similarities raise the question of the extent of their relationship...
December 27, 2017: Journal of Anatomy
https://www.readbyqxmd.com/read/29258947/a-novel-method-to-measure-the-tentorial-angle-and-the-implications-on-surgeries-of-the-pineal-region
#18
Hasan R Syed, Walter C Jean
OBJECTIVE: There is no standard way to define the angle of the tentorium. The current trend to use the Twining line to define this angle has significant pitfalls. The goal of the current study is to provide a new and accurate way to measure the "tentorial angle," and demonstrate its impact on surgeries of the pineal region. METHODS: A new technique (n-angle) to measure the tentorial angle is introduced using the floor of the fourth ventricle and the torcula. Comparisons to older techniques were made to illustrate reliability...
December 16, 2017: World Neurosurgery
https://www.readbyqxmd.com/read/29258935/low-retrosigmoid-infratonsillar-approach-to-lateral-medullary-lesions
#19
Baran Bozkurt, M Yashar S Kalani, Kaan Yağmurlu, Evgenii Belykh, Mark C Preul, Peter Nakaji, Robert F Spetzler
OBJECTIVE: In our study, we comprehensively detail the technique of the low retrosigmoid approach to the lateral medullary area, including the inferior cerebellar peduncle, postolivary sulcus, pontomedullary sulcus, and inferior olivary nucleus, as well as the lateral recess of the fourth ventricle. METHODS: Four formalin-fixed, silicone-injected, cadaveric human heads were examined under the operating microscope to demonstrate the pertinent descriptive anatomy using the low retrosigmoid approach in a stepwise manner...
December 16, 2017: World Neurosurgery
https://www.readbyqxmd.com/read/29250844/intractable-epilepsy-due-to-a-rosette-forming-glioneuronal-tumor-with-a-dysembryoplastic-neuroepithelial-background
#20
Noriko Sumitomo, Akihiko Ishiyama, Makoto Shibuya, Eiji Nakagawa, Yu Kaneko, Akio Takahashi, Taisuke Otsuki, Akiyoshi Kakita, Yuko Saito, Noriko Sato, Kenji Sugai, Masayuki Sasaki
A rosette-forming glioneuronal tumor (RGNT) was initially reported as an infratentorial tumor that comprised both small neurocytic rosettes and astrocytic components. However, a few studies have reported supratentorial RGNTs arising in the cerebral hemispheres. Here, we report an unusual case involving a 9-year-old boy with a supratentorial RGNT who presented with intractable epilepsy and behavioral changes. Brain MRI revealed a well-circumscribed space-occupying lesion with septae in the right inferomedial parietal lobe...
December 18, 2017: Neuropathology: Official Journal of the Japanese Society of Neuropathology
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