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https://www.readbyqxmd.com/read/28515196/cost-effectiveness-of-therapist-guided-internet-delivered-cognitive-behaviour-therapy-for-paediatric-obsessive-compulsive-disorder-results-from-a-randomised-controlled-trial
#1
Fabian Lenhard, Richard Ssegonja, Erik Andersson, Inna Feldman, Christian Rück, David Mataix-Cols, Eva Serlachius
OBJECTIVES: To evaluate the cost-effectiveness of a therapist-guided internet-delivered cognitive behaviour therapy (ICBT) intervention for adolescents with obsessive-compulsive disorder (OCD) compared with untreated patients on a waitlist. DESIGN: Single-blinded randomised controlled trial. SETTING: A research clinic within the regular child and adolescent mental health service in Stockholm, Sweden. PARTICIPANTS: Sixty-seven adolescents (12-17 years) with a Diagnostic and Statistical Manual of Mental Disorders Fifth Edition diagnosis of OCD...
May 17, 2017: BMJ Open
https://www.readbyqxmd.com/read/28512441/mapping-the-paths-from-styles-of-anger-experience-and-expression-to-obsessive-compulsive-symptoms-the-moderating-roles-of-family-cohesion-and-adaptability
#2
Liang Liu, Cuilian Liu, Xudong Zhao
Previous research has shown strong connections of anger experience and expression with obsessive-compulsive (OC) symptoms. Additionally, studies have demonstrated links between family environment variables and obsessive-compulsive disorder (OCD). Our study aims to integrate the perspectives from these two literatures by exploring the moderating roles of family cohesion and family adaptability in the relationship between anger proneness and suppression and OCD symptoms. A total of 2008 college students were recruited from a comprehensive university in Shanghai, China between February and May 2016...
2017: Frontiers in Psychology
https://www.readbyqxmd.com/read/28509714/preventing-occupational-skin-disease-a-review-of-training-programs
#3
Bethany Zack, Victoria H Arrandale, D Linn Holness
Occupational contact dermatitis (OCD) is a common occupational disease that impacts a variety of worker groups. Skin protection and disease prevention training programs have shown promise for improving prevention practices and reducing the incidence of OCD. This review details the features of training programs for primary prevention of OCD and identifies gaps in the literature. Twelve studies were identified for in-depth review: many studies included wet workers employed in health care, hairdressing, cleaning, and food preparation; 1 program featured manufacturing workers...
May 2017: Dermatitis
https://www.readbyqxmd.com/read/28505489/anxiety-sensitivity-as-a-predictor-of-outcome-in-the-treatment-of-obsessive-compulsive-disorder
#4
Shannon M Blakey, Jonathan S Abramowitz, Lillian Reuman, Rachel C Leonard, Bradley C Riemann
BACKGROUND AND OBJECTIVES: To address the fact that not all individuals who receive cognitive-behavioral therapy (CBT) for obsessive-compulsive disorder (OCD) exhibit complete symptom reduction, research has examined factors that predict outcome; however, no studies have examined anxiety sensitivity (AS) as a predictor of outcome of CBT for OCD. AS refers to the fear of anxious arousal that results from mistaken beliefs about the dangerousness of anxiety-related body sensations. It is important to understand whether AS influences OCD treatment outcome, considering that (a) some obsessions directly relate to AS, and (b) OCD patients with high AS may be reluctant to engage in anxiety-provoking components of CBT for OCD...
May 6, 2017: Journal of Behavior Therapy and Experimental Psychiatry
https://www.readbyqxmd.com/read/28504027/epidemiology-and-comorbidity-of-obsessive-compulsive-disorder-in-late-adolescence-a-cross-sectional-study-in-senior-high-schools-in-greece
#5
Spyridon Politis, Konstantina Magklara, Petros Petrikis, Grigorios Michalis, Gregoris Simos, Petros Skapinakis
OBJECTIVE: The aim of this study was to examine the epidemiology, comorbidity and use of health services of obsessive-compulsive disorder (OCD) and subclinical obsessive-compulsive symptoms in late adolescence. METHODS: A total of 2427 adolescents attending senior high schools in Greece were selected for a detailed psychiatric interview using the revised clinical interview schedule (CIS-R). Use of alcohol, nicotine and cannabis, and several socio-demographic and socio-economic variables were also assessed...
May 15, 2017: International Journal of Psychiatry in Clinical Practice
https://www.readbyqxmd.com/read/28485008/l-carnosine-as-an-adjuvant-to-fluvoxamine-in-treatment-of-obsessive-compulsive-disorder-a-randomized-double-blind-study
#6
Somaye Arabzadeh, Maryam Shahhossenie, Bita Mesgarpour, Farzin Rezaei, Mohammad Reza Shalbafan, Zahra Ghiasi, Shahin Akhondzadeh
BACKGROUND: Dysregulation of glutamate is implicated in the pathogenesis of obsessive-compulsive disorder (OCD). Consistently, glutamate-modulating agents, such as riluzole and memantine have been used in OCD treatment. Previous research has identified some neuroprotective role for L-carnosine potentially via its modulatory effect on glutamate. Here, we assessed the efficacy of L-carnosine as adjuvant to fluvoxamine in OCD treatment. METHODS: Forty-four patients diagnosed with moderate to severe OCD were recruited in a randomized double-blind trial...
May 8, 2017: Human Psychopharmacology
https://www.readbyqxmd.com/read/28478887/investigating-the-neurobiology-of-schizophrenia-and-other-major-psychiatric-disorders-with-transcranial-magnetic-stimulation
#7
REVIEW
Rachel E Kaskie, Fabio Ferrarelli
Characterizing the neurobiology of schizophrenia and other major psychiatric disorders is one of the main challenges of the current research in psychiatry. The availability of Transcranial Magnetic Stimulation (TMS) allows to directly probe virtually any cortical areas, thus providing a unique way to assess the neurophysiological properties of cortical neurons. This article presents a review of studies employing TMS in combination with Motor Evoked Potentials (TMS/MEPs) and high density Electroencephalogram (TMS/hd-EEG) in schizophrenia and other major psychiatric disorders...
May 3, 2017: Schizophrenia Research
https://www.readbyqxmd.com/read/28471212/hierarchical-structure-of-emotional-disorders-from-individual-symptoms-to-the-spectrum
#8
Monika A Waszczuk, Roman Kotov, Camilo Ruggero, Wakiza Gamez, David Watson
Classification of emotional disorders faces challenges of within-disorder heterogeneity and between-disorder comorbidity. The current study addressed these issues by analyzing all emotional disorder symptoms to identify homogeneous dimensions that characterize this domain. These dimensions were, in turn, used to define coherent syndromes and higher order factors. All of the emotional disorder symptoms specified in diagnostic manuals were assessed by interview in 2 treatment-seeking samples (N = 426 and 305), alongside clinical diagnoses and functioning measures...
May 4, 2017: Journal of Abnormal Psychology
https://www.readbyqxmd.com/read/28457837/cost-effectiveness-of-deep-brain-stimulation-versus-treatment-as-usual-for-obsessive-compulsive-disorder
#9
Pieter Ooms, Matthijs Blankers, Martijn Figee, Isidoor O Bergfeld, Pepijn van den Munckhof, P Richard Schuurman, Damiaan Denys
BACKGROUND: Deep Brain Stimulation (DBS) is effective for obsessive-compulsive disorder (OCD), but requires expensive medical procedures. To date, no study has examined the cost-effectiveness of DBS for OCD. OBJECTIVE: To perform the first economic evaluation of DBS for therapy refractory OCD. METHODS: We conducted a 2-year prospective, open cost-effectiveness study, comparing DBS (n = 17) with treatment as usual (TAU) (n = 11), with cost per Quality-Adjusted-Life-Year (QALY) as outcome measure...
April 13, 2017: Brain Stimulation
https://www.readbyqxmd.com/read/28453999/symptoms-of-obsessive-compulsive-disorder-predict-cannabis-misuse
#10
Alexander Spradlin, Dakota Mauzay, Carrie Cuttler
INTRODUCTION: Cannabis use has been linked to many psychological disorders. There is, however, a paucity of research investigating the link between cannabis use and obsessive-compulsive disorder (OCD). The present study sought to examine this link by exploring associations between severity of OCD symptoms, cannabis use, and cannabis misuse; determining whether these associations exist above and beyond symptoms of anxiety, depression, and stress; and testing the mediating role of cannabis coping motives (i...
March 31, 2017: Addictive Behaviors
https://www.readbyqxmd.com/read/28434589/from-an-animal-model-to-human-patients-an-example-of-a-translational-study-on-obsessive-compulsive-disorder-ocd
#11
REVIEW
David Eilam
The application of similar analyses enables a direct projection from translational research in animals to human studies. Following is an example of how the methodology of a specific animal model of obsessive-compulsive disorder (OCD) was applied to study human patients. Specifically, the quinpirole rat model for OCD was based on analyzing the trajectories of travel among different locales, and scoring the set of acts performed at each locale. Applying this analytic approach in human patients unveiled various aspects of OCD, such as the repetition and addition of acts, incompleteness, and the link between behavior and specific locations...
May 2017: Neuroscience and Biobehavioral Reviews
https://www.readbyqxmd.com/read/28433854/comorbidity-age-of-onset-and-suicidality-in-obsessive-compulsive-disorder-ocd-an-international-collaboration
#12
V Brakoulias, V Starcevic, A Belloch, C Brown, Y A Ferrao, L F Fontenelle, C Lochner, D Marazziti, H Matsunaga, E C Miguel, Ycj Reddy, M C do Rosario, R G Shavitt, A Shyam Sundar, D J Stein, A R Torres, K Viswasam
OBJECTIVES: To collate data from multiple obsessive-compulsive disorder (OCD) treatment centers across seven countries and five continents, and to report findings in relation to OCD comorbidity, age of onset of OCD and comorbid disorders, and suicidality, in a large clinical and ethnically diverse sample, with the aim of investigating cultural variation and the utility of the psychiatric diagnostic classification of obsessive-compulsive and related disorders. METHODS: Researchers in the field of OCD were invited to contribute summary statistics on current and lifetime psychiatric comorbidity, age of onset of OCD and comorbid disorders and suicidality in their patients with OCD...
April 12, 2017: Comprehensive Psychiatry
https://www.readbyqxmd.com/read/28432894/the-structure-correlates-and-treatment-related-changes-of-mindfulness-facets-across-the-anxiety-disorders-and-obsessive-compulsive-disorder
#13
Lance L Hawley, Jenny Rogojanski, Valerie Vorstenbosch, Lena C Quilty, Judith M Laposa, Neil A Rector
Research with non-clinical and clinical samples has examined how mindfulness concepts relate to psychological symptom presentations. However, there is less clarity when examining treatment-seeking patients who experience DSM-diagnosed anxiety and obsessional disorders - both cross-sectionally, and following empirically-supported treatments. The Five Facet Mindfulness Questionnaire (FFMQ; Baer, Smith, Hopkins, Krietemeyer, & Toney, 2006) conceptualizes mindfulness as consisting of five facets: Observing, Describing, Acting with Awareness, Nonreactivity, and Nonjudging...
March 14, 2017: Journal of Anxiety Disorders
https://www.readbyqxmd.com/read/28414963/three-dimensional-excitation-and-emission-matrix-fluorescence-3deem-for-quick-and-pseudo-quantitative-determination-of-protein-and-humic-like-substances-in-full-scale-membrane-bioreactor-mbr
#14
Céline Jacquin, Geoffroy Lesage, Jacqueline Traber, Wouter Pronk, Marc Heran
The goal of this study is to help filling the research gaps linked to the on-line application of fluorescence spectroscopy in wastewater treatment and data processing tools suitable for rapid correction and extraction of data contained in three-dimensional fluorescence excitation-emission matrix (3DEEM) for real-time studies. 3DEEM was evaluated for direct quantification of Effluent Organic Matter (EfOM) fractions in full-scale MBR bulk supernatant and permeate samples. Principal Component Analysis (PCA) was used to investigate possible correlations between conventional Lowry and Dubois methods, Liquid Chromatography coupled to Organic Carbon and Organic Nitrogen Detection (LC-OCD-OND) and 3DEEM...
July 1, 2017: Water Research
https://www.readbyqxmd.com/read/28398084/the-reliability-of-assessing-radiographic-healing-of-osteochondritis-dissecans-of-the-knee
#15
Eric J Wall, Matthew D Milewski, James L Carey, Kevin G Shea, Theodore J Ganley, John D Polousky, Nathan L Grimm, Emily A Eismann, Jake C Jacobs, Lucas Murnaghan, Carl W Nissen, Gregory D Myer, Jennifer Weiss, Eric W Edmonds, Allen F Anderson, Roger M Lyon, Benton E Heyworth, Peter D Fabricant, Andy Zbojniewicz
BACKGROUND: The reliability of assessing healing on plain radiographs has not been well-established for knee osteochondritis dissecans (OCD). PURPOSE: To determine the inter- and intrarater reliability of specific radiographic criteria in judging healing of femoral condyle OCD. STUDY DESIGN: Cohort study (Diagnosis); Level of evidence, 3. METHODS: Ten orthopedic sports surgeons rated the radiographic healing of 30 knee OCD lesions at 2 time points, a minimum of 1 month apart...
May 2017: American Journal of Sports Medicine
https://www.readbyqxmd.com/read/28397354/seeking-help-for-obsessive-compulsive-disorder-ocd-a-qualitative-study-of-the-enablers-and-barriers-conducted-by-a-researcher-with-personal-experience-of-ocd
#16
Karen J Robinson, Diana Rose, Paul M Salkovskis
OBJECTIVES: Obsessive compulsive disorder (OCD) can be hugely disabling. Although very effective psychological treatments exist, many people delay years before seeking help or never seek treatment. There have been clinical observation and short questionnaire studies on why people delay, but little qualitative research exists on this complex subject. The present qualitative study aimed to identify the barriers to seeking treatment and the factors that encourage or push people to seek help for their OCD (positive and negative enablers)...
April 10, 2017: Psychology and Psychotherapy
https://www.readbyqxmd.com/read/28390444/the-relationship-between-obsessive-compulsive-personality-and-obsessive-compulsive-disorder-treatment-outcomes-predictive-utility-and-clinically-significant-change
#17
Shalane K Sadri, Peter M McEvoy, Sarah J Egan, Robert T Kane, Clare S Rees, Rebecca A Anderson
BACKGROUND: The evidence regarding whether co-morbid obsessive compulsive personality disorder (OCPD) is associated with treatment outcomes in obsessive compulsive disorder (OCD) is mixed, with some research indicating that OCPD is associated with poorer response, and some showing that it is associated with improved response. AIMS: We sought to explore the role of OCPD diagnosis and the personality domain of conscientiousness on treatment outcomes for exposure and response prevention for OCD...
April 9, 2017: Behavioural and Cognitive Psychotherapy
https://www.readbyqxmd.com/read/28390295/examining-procedural-working-memory-processing-in-obsessive-compulsive-disorder
#18
Nitzan Shahar, Andrei R Teodorescu, Gideon E Anholt, Anat Karmon-Presser, Nachshon Meiran
Previous research has suggested that a deficit in working memory might underlie the difficulty of obsessive-compulsive disorder (OCD) patients to control their thoughts and actions. However, a recent meta-analyses found only small effect sizes for working memory deficits in OCD. Recently, a distinction has been made between declarative and procedural working memory. Working memory in OCD was tested mostly using declarative measurements. However, OCD symptoms typically concerns actions, making procedural working-memory more relevant...
March 27, 2017: Psychiatry Research
https://www.readbyqxmd.com/read/28375077/ocd-obsessive-compulsive-%C3%A2-disgust-the-role-of-disgust-in-obsessive-compulsive-disorder
#19
Tracy Bhikram, Elia Abi-Jaoude, Paul Sandor
Recent research has identified the important role of disgust in the symptomatology of obsessive-compulsive disorder (OCD). Exaggerated and inappropriate disgust reactions may drive some of the symptoms of OCD, and in some cases, may even eclipse feelings of anxiety. This paper reviews behavioural and neuroimaging research that recognizes the prominent role of disgust in contributing to OCD symptoms, especially contamination-based symptoms. We discuss how elevated behavioural and biological markers of disgust reported in OCD populations support the need for alternative clinical treatment strategies and theoretical models of OCD...
April 4, 2017: Journal of Psychiatry & Neuroscience: JPN
https://www.readbyqxmd.com/read/28375061/novel-biotherapies-are-needed-in-youth-mental-health
#20
G Paul Amminger, Maximus Berger, Simon M Rice, Christopher G Davey, Miriam R Schäfer, Patrick D McGorry
Adverse effects and lack of efficacy in a significant number of patients limit pharmaceutical interventions in youth psychiatry. This is exemplified by the fact that no medication is currently approved for the treatment of non-OCD anxiety disorders or major depressive disorder in young people younger than 18 years of age in Australia. Here, emerging biological therapies for youth with mental health problems are discussed. There is an urgent need for more research into biological interventions with acceptable risk-benefit balances...
April 2017: Australasian Psychiatry: Bulletin of Royal Australian and New Zealand College of Psychiatrists
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