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https://www.readbyqxmd.com/read/27887679/-mindfulness-based-interventions-in-obsessive-compulsive-disorder-mechanisms-of-action-and-presentation-of-a-pilot-study
#1
M Gasnier, A Pelissolo, G Bondolfi, S Pelissolo, M Tomba, L Mallet, K N'diaye
Obsessive-compulsive disorder (OCD) is a frequent and severe disease, potentially inducing a major impairment for the patient and burden for their family. Recent research in psychiatry and neuroscience have led to better comprehension of the disease's mechanisms and helped to improve its treatment. However, a large proportion of patients have refractory symptoms, including for traditional cognitive and behavioral therapy by exposure and response prevention (ERP), leading clinicians to look for new treatments...
November 22, 2016: L'Encéphale
https://www.readbyqxmd.com/read/27612144/use-of-selective-serotonin-reuptake-inhibitors-and-risks-of-stroke-in-patients-with-obsessive-compulsive-disorder-a-population-based-study
#2
Che-Sheng Chu, Po-Han Chou, Ching-Heng Lin, Chin Cheng, Chia-Jui Tsai, Tsuo-Hung Lan, Min-Wei Huang, Gerald Nestadt
BACKGROUND: Previous research has suggested a link between antidepressants use and the development of cerebrovascular events, but there has never been any study investigating the risk of stroke in obsessive-compulsive disorder (OCD) patients treated with a selective serotonin reuptake inhibitor (SSRI). METHODS: A retrospective observational cohort study was conducted using data from the National Health Insurance Database of Taiwan between the year of 2001 and 2009...
2016: PloS One
https://www.readbyqxmd.com/read/27570959/-on-the-university-of-recovery
#3
Jean-François Pelletier, Christine Boisvert, Marie-Claude Galipeau-Leduc, Christian Ducasse, Denis Pouliot-Morneau, Julie Bordeleau
Objectives Located at the heart of a mental health university institute in Montreal, Canada, the University of Recovery (UR) is a peer-run agency of service users who came together as a private non-profit organization to promote their experiential knowledge in science and public health, and to transform the academic milieu as an inclusive work environment conducive to recovery and full citizenship. UR students can thus have access to scientific conferences and classes on various topics and invite scientists or other professionals to further discuss new discoveries and techniques, and possible ways of improving healthcare from a patients' and service users' perspective...
2016: Santé Mentale Au Québec
https://www.readbyqxmd.com/read/27477178/trichotillomania-bizzare-patern-of-hair-loss-at-11-year-old-girl
#4
Jana Zímová, Pavlína Zímová
Trichotillomania (TTM) is defined by the Diagnostics and Statistic Manual of Mental Disorders, 4th edition (DMS-IV) as hair loss from a patient`s repetitive self-pulling of hair. The disorder is included under anxiety disorders because it shares some obsessive-compulsive features. Patients have the tendency towards feelings of unattractiveness, body dissatisfaction, and low self-esteem (1,2). It is a major psychiatric problem, but many patients with this disorder first present to a dermatologist. An 11-year-old girl came to our department with a 2-month history of diffuse hair loss on the frontoparietal and parietotemporal area (Figure 1)...
June 2016: Acta Dermatovenerologica Croatica: ADC
https://www.readbyqxmd.com/read/27013594/brief-strategic-therapy-for-obsessive-compulsive-disorder-a-clinical-and-research-protocol-of-a-one-group-observational-study
#5
Giada Pietrabissa, Gian Mauro Manzoni, Padraic Gibson, Donald Boardman, Alessio Gori, Gianluca Castelnuovo
INTRODUCTION: Obsessive-compulsive disorder (OCD) is a disabling psychopathology. The mainstay of treatment includes cognitive-behavioural therapy (CBT) and medication management. However, individual suffering, functional impairments as well as the direct and indirect costs associated with the disease remain substantial. New treatment programmes are necessary and the brief strategic therapy (BST) has recently shown encouraging results in clinical practice but no quantitative study has as yet been conducted...
2016: BMJ Open
https://www.readbyqxmd.com/read/26983548/glutamatergic-medication-in-the-treatment-of-obsessive-compulsive-disorder-ocd-and-autism-spectrum-disorder-asd-study-protocol-for-a-randomised-controlled-trial
#6
Alexander Häge, Tobias Banaschewski, Jan K Buitelaar, Rick M Dijkhuizen, Barbara Franke, David J Lythgoe, Konstantin Mechler, Steven C R Williams, Ralf W Dittmann
BACKGROUND: Compulsivity is a cross-disorder trait underlying phenotypically distinct psychiatric disorders that emerge in childhood or adolescence. Despite the effectiveness of serotonergic compounds in the treatment of obsessive-compulsive disorder, treatment-resistant symptoms remaining in 40 to 60 % of patients present a pressing clinical problem. There are currently no medications that effectively treat the core impairments of autism spectrum disorder. There is an urgent need for the development of conceptually novel pharmacological strategies...
2016: Trials
https://www.readbyqxmd.com/read/26584571/psychotropic-treatments-in-prader-willi-syndrome-a-critical-review-of-published-literature
#7
REVIEW
O Bonnot, D Cohen, D Thuilleaux, A Consoli, S Cabal, M Tauber
UNLABELLED: Prader-Willi syndrome (PWS) is a rare genetic syndrome. The phenotype includes moderate to intellectual disability, dysmorphia, obesity, and behavioral disturbances (e.g., hetero and self-injurious behaviors, hyperphagia, psychosis). Psychotropic medications are widely prescribed in PWS for symptomatic control. We conducted a systematic review of published literature to examine psychotropic medications used in PWS. MEDLINE was searched to identify articles published between January 1967 and December 2014 using key words related to pharmacological treatments and PWS...
January 2016: European Journal of Pediatrics
https://www.readbyqxmd.com/read/26143395/recent-trends-in-occupational-contact-dermatitis
#8
REVIEW
Marta Wiszniewska, Jolanta Walusiak-Skorupa
Occupational contact dermatitis (OCD) remains prevalent among workers and impacts quality of life and workability. The purpose of this review is to summarize the recent advances in occupational contact dermatitis as well as potential hazardous agents in the workplaces causing OCD. The review covers new developments in the epidemiology, etiology, diagnosis, and management of occupational contact dermatitis. This article also provides updated information on the prevalence of work-related skin symptoms and on new contact allergens among working population...
July 2015: Current Allergy and Asthma Reports
https://www.readbyqxmd.com/read/26132683/half-of-obsessive-compulsive-disorder-cases-misdiagnosed-vignette-based-survey-of-primary-care-physicians
#9
Kimberly Glazier, Matt Swing, Lata K McGinn
OBJECTIVE: Medical settings are the primary mode of care for mental health problems; physicians' abilities with regard to psychiatric diagnosis and treatment recommendations are therefore essential. While misdiagnosis can occur across all psychiatric conditions, the heterogeneous nature of obsessive-compulsive disorder (OCD) may make this condition at an elevated risk for misidentification. The study's aim was to assess primary care physicians' ability to identify OCD. METHOD: The study was cross-sectional in design...
June 2015: Journal of Clinical Psychiatry
https://www.readbyqxmd.com/read/25911281/in-the-wake-of-a-possible-mistake-security-motivation-checking-behavior-and-ocd
#10
RANDOMIZED CONTROLLED TRIAL
Andrea L Hinds, Erik Z Woody, Louis A Schmidt, Michael Van Ameringen, Henry Szechtman
BACKGROUND AND OBJECTIVES: In previous experiments, OCD washers did not differ significantly from controls in their initial level of activation in response to the potential threat of contamination; however, they were less able to reduce their activation by engaging in hand-washing, suggesting that the key problem in OCD is a faulty stopping mechanism. The main objectives of the present experiments were to develop a similar experimental paradigm for investigating checking behavior, and to use it to test the hypothesis that a faulty stopping mechanism also underlies OCD checking...
December 2015: Journal of Behavior Therapy and Experimental Psychiatry
https://www.readbyqxmd.com/read/25669954/-psychiatric-aspects-of-tics
#11
D Cath
BACKGROUND: Tics, the most serious form of which is the Gilles de la Tourette syndrome (GTS), belong to the group of hyperkinetic movement disorders. The most extreme forms of these movement disorders are often characterised by psychiatric comorbidity. AIM: To acquaint the reader with the psychiatric aspects of tics and with the role played by comorbidities in OCD and ADHD patients who also suffer from tics. METHOD: Recent new insights in psychiatric aspects of GTS are described...
2015: Tijdschrift Voor Psychiatrie
https://www.readbyqxmd.com/read/25506052/the-virtual-patient-simulator-of-deep-brain-stimulation-in-the-obsessive-compulsive-disorder-based-on-connectome-and-7-tesla-mri-data
#12
Giorgio Bonmassar, Nikos Makris
We present work in progress on the virtual patient model for patients with Deep Brain Stimulation (DBS) implants based on Connectome and 7 Tesla Magnetic Resonance Imaging (MRI) data. Virtual patients are realistic computerized models of patients that allow medical-device companies to test new products earlier, helping the devices get to market more quickly and cheaply according to the Food and Drug Administration. We envision that the proposed new virtual patient simulator will enable radio frequency power dosimetry on patients with the DBS implant undergoing MRI...
2014: International Conference on Advanced Cognitive Technologies and Applications
https://www.readbyqxmd.com/read/25421403/bilateral-thermal-capsulotomy-with-mr-guided-focused-ultrasound-for-patients-with-treatment-refractory-obsessive-compulsive-disorder-a-proof-of-concept-study
#13
H H Jung, S J Kim, D Roh, J G Chang, W S Chang, E J Kweon, C-H Kim, J W Chang
Despite optimal pharmacotherapy and cognitive-behavioral treatments, a proportion of patients with obsessive-compulsive disorder (OCD) remain refractory to treatment. Neurosurgical ablative or nondestructive stimulation procedures to treat these refractory patients have been investigated. However, despite the potential benefits of these surgical procedures, patients show significant surgery-related complications. This preliminary study investigated the use of bilateral thermal capsulotomy for patients with treatment-refractory OCD using magnetic resonance-guided focused ultrasound (MRgFUS) as a novel, minimally invasive, non-cranium-opening surgical technique...
October 2015: Molecular Psychiatry
https://www.readbyqxmd.com/read/25150561/obsessive-compulsive-disorder
#14
REVIEW
Wayne K Goodman, Dorothy E Grice, Kyle A B Lapidus, Barbara J Coffey
This article reviews the clinical features and neurochemical hypotheses of obsessive-compulsive disorder (OCD) with a focus on the serotonin system. In DSM-5, OCD was moved from the anxiety disorders to a new category of Obsessive-Compulsive and Related Disorders. OCD is a common, typically persistent disorder marked by intrusive and disturbing thoughts (obsessions) and repetitive behaviors (compulsions) that the person feels driven to perform. The preferential efficacy of serotonin reuptake inhibitors (SRIs) in OCD led to the so-called serotonin hypothesis...
September 2014: Psychiatric Clinics of North America
https://www.readbyqxmd.com/read/25046040/interpersonal-functioning-in-obsessive-compulsive-personality-disorder
#15
Nicole M Cain, Emily B Ansell, H Blair Simpson, Anthony Pinto
The core symptoms of obsessive-compulsive personality disorder (OCPD) often lead to interpersonal difficulties. However, little research has explored interpersonal functioning in OCPD. This study examined interpersonal problems, interpersonal sensitivities, empathy, and systemizing, the drive to analyze and derive underlying rules for systems, in a sample of 25 OCPD individuals, 25 individuals with comorbid OCPD and obsessive-compulsive disorder (OCD), and 25 healthy controls. We found that OCPD individuals reported hostile-dominant interpersonal problems and sensitivities with warm-dominant behavior by others, whereas OCPD+OCD individuals reported submissive interpersonal problems and sensitivities with warm-submissive behavior by others...
2015: Journal of Personality Assessment
https://www.readbyqxmd.com/read/24940965/a-benzisothiazole-derivative-and-antipsychotic-agent-perospirone-for-augmentation-of-selective-serotonin-reuptake-inhibitors-ssris-in-refractory-obsessive-compulsive-disorder-ocd-two-patient-case-series
#16
Hisato Matsunaga, Tokuzo Matsui, Kenzo Ohya, Kenya Okino, Kazuhisa Hayashida, Kensei Maebayashi, Nobuo Kiriike, Dan J Stein
Even though selective serotonin reuptake inhibitors (SSRIs) are the mainstay of pharamacological treatment for obsessive-compulsive disorder (OCD), as many as 40% of patients do not have an adequate response to these medications. For such SSRI-refractory patients, the augmentation of SSRIs with new-generation antipsychotics that modulate both 5-HT and DA systems has recently been proven effective in controlled augmentation studies. The benzisothiazole derivative perospirone is a new serotonin 5-HT2 and dopamine D2 antagonist available in Japan for the treatment of schizophrenia...
2006: International Journal of Psychiatry in Clinical Practice
https://www.readbyqxmd.com/read/24867863/prevalence-and-profile-of-obsessive-compulsive-trait-in-patients-with-chronic-migraine-and-medication-overuse
#17
M Curone, V Tullo, C Lovati, A Proietti-Cecchini, D D'Amico
Patients with chronic migraine (CM) and medication overuse headache (MOH) have high frequency of psychiatric comorbidity or psychopathological traits, the presence of which can influence the clinical course. The presence of subclinical obsessive compulsive disorder (OCD) is underestimated in migraine patients. The aim of this study was to estimate the prevalence and profile of obsessive-compulsive (OBS) trait in a sample of CM patients with MOH using the OBS questionnaire of Spectrum Collaborative Project. According to the new international classification of headache disorders (ICHD-III beta) criteria, 106 patients (15 M, 91 F, mean age 47...
May 2014: Neurological Sciences
https://www.readbyqxmd.com/read/24616177/dsm-5-obsessive-compulsive-and-related-disorders-clinical-implications-of-new-criteria
#18
REVIEW
Michael Van Ameringen, Beth Patterson, William Simpson
For the publication of DSM-5, obsessive-compulsive disorder (OCD) was the subject of significant revisions to its classification and diagnostic criteria. One of these significant changes was the placement of OCD in a new category, "Obsessive-Compulsive and Related Disorders (OCRDs)," which also includes body dysmorphic disorder (BDD), trichotillomania (hair-pulling disorder), excoriation (skin-picking) disorder, hoarding disorder, substance/medication-induced OCRD, OCRD due to another medical condition, and other specified OCRDs...
June 2014: Depression and Anxiety
https://www.readbyqxmd.com/read/24599398/d2-and-d3-dopamine-receptor-affinity-predicts-effectiveness-of-antipsychotic-drugs-in-obsessive-compulsive-disorders-a-metaregression-analysis
#19
Deborah Ducasse, Laurent Boyer, Pierre Michel, Anderson Loundou, Alexandra Macgregor, Jean-Arthur Micoulaud-Franchi, Philippe Courtet, Mocrane Abbar, Marion Leboyer, Guillaume Fond
RATIONALE AND OBJECTIVE: The relationship between clinically effective antipsychotic drugs in obsessive-compulsive disorders (OCD) and binding affinities to cloned dopamine and serotonin receptor subtypes was analyzed in an effort to clarify the contribution of individual receptor subtypes to medication response. METHODS: Meta-analysis was used to update previous meta-analyses of effectiveness data of add-on antipsychotic drugs to selective serotonin reuptake inhibitors (SSRIs) in OCD...
September 2014: Psychopharmacology
https://www.readbyqxmd.com/read/24568979/the-long-term-outcomes-of-ocular-tics-in-a-pediatric-neuro-ophthalmology-practice
#20
Esther R Bisker, Collin M McClelland, Lawrence W Brown, Grant T Liu
PURPOSE: To describe the outcome and comorbidities of ocular tics in children evaluated by a pediatric neuro-ophthalmologist. METHODS: The medical records of all consecutive patients in a pediatric neuro-ophthalmology practice diagnosed with ocular tics (eye rolling, blinking, and widening) were retrospectively reviewed. Children with known secondary causes for tics were excluded. Patients, parents, and/or guardians were contacted by telephone to obtain follow-up information...
February 2014: Journal of AAPOS: the Official Publication of the American Association for Pediatric Ophthalmology and Strabismus
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