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self monitoring in type 2 diabetes

George Grunberger, Yehuda Handelsman, Zachary T Bloomgarden, Vivian A Fonseca, Alan J Garber, Richard A Haas, Victor L Roberts, Guillermo E Umpierrez
This document represents the official position of the American Association of Clinical Endocrinologists and American College of Endocrinology. Where there are no randomized controlled trials or specific U.S. FDA labeling for issues in clinical practice, the participating clinical experts utilized their judgment and experience. Every effort was made to achieve consensus among the committee members. Position statements are meant to provide guidance, but they are not to be considered prescriptive for any individual patient and cannot replace the judgment of a clinician...
March 2018: Endocrine Practice
(no author information available yet)
Background: Type 1 diabetes is a condition in which the pancreas produces little or no insulin. People with type 1 diabetes must manage their blood glucose levels by monitoring the amount of glucose in their blood and administering appropriate amounts of insulin via injection or an insulin pump. Continuous glucose monitoring may be beneficial compared to self-monitoring of blood glucose using a blood glucose meter. It provides insight into a person's blood glucose levels on a continuous basis, and can identify whether blood glucose levels are trending up or down...
2018: Ontario Health Technology Assessment Series
Edlira Lashi, Fatos Lashi, Klotilda Muca, Bora Ballta, Suzana Kazazi
AIM: Identification of glycemic level tendency rates in a hypertonic population that suffers from diabetes mellitus in Health Centre Nr. 1, Tirana, evaluation of self-monitoring and the effects of interactions, with the aim of reducing the levels of fast glycaemia in these patients. MATERIAL AND METHODS: In the study participated 810 patients of Health Centre Nr 1 in Tirana that suffer from hypertension and diabetes mellitus type 1 and 2. The study was conducted through 10 months' period...
February 15, 2018: Open Access Macedonian Journal of Medical Sciences
Clara Tasende, José Antonio Rubio, Julia Álvarez
BACKGROUND AND OBJECTIVE: The negative impact of hypoglycemia on patients with type 1 diabetes mellitus (T1DM) may lead to development of fear of hypoglycemia. In this study, the original Hypoglycemia Fear Survey (HFS) questionnaire was translated into Spanish, adapted and validated, and variables associated to fear of hypoglycemia in T1DM were analyzed. MATERIAL AND METHODS: The HFS was translated and adapted to Spanish using the forward-backward translation method...
March 7, 2018: Endocrinología, Diabetes y Nutrición
Martin Haluzik, Adam Kretowski, Krzysztof Strojek, Leszek Czupryniak, Andrej Janez, Peter Kempler, Michal Andel, Tsvetalina Tankova, Mihail Boyanov, Lea Smircic Duvnjak, Laszlo Madacsy, Iwona Tarnowska, Marcin Zychma, Nebojsa Lalic
INTRODUCTION: The aim of this study was to determine the level of awareness of hypoglycemia, the level of fear for hypoglycemia, and the response to hypoglycemic events among insulin-treated diabetes patients from Central and Eastern Europe (CEE). The impact of hypoglycemia on the use of healthcare resources and patient productivity was also assessed. METHODS: This was a multicenter, non-interventional, two-part, patient self-reported questionnaire study that comprised both a retrospective cross-sectional evaluation and a prospective observational evaluation...
March 9, 2018: Diabetes Therapy: Research, Treatment and Education of Diabetes and related Disorders
Bahendeka Silver, Kaushik Ramaiya, Swai Babu Andrew, Otieno Fredrick, Sarita Bajaj, Sanjay Kalra, Bavuma M Charlotte, Karigire Claudine, Anthony Makhoba
A diagnosis of diabetes or hyperglycemia should be confirmed prior to ordering, dispensing, or administering insulin (A). Insulin is the primary treatment in all patients with type 1 diabetes mellitus (T1DM) (A). Typically, patients with T1DM will require initiation with multiple daily injections at the time of diagnosis. This is usually short-acting insulin or rapid-acting insulin analogue given 0 to 15 min before meals together with one or more daily separate injections of intermediate or long-acting insulin...
March 5, 2018: Diabetes Therapy: Research, Treatment and Education of Diabetes and related Disorders
Kyung Soo Kim
No abstract text is available yet for this article.
February 2018: Diabetes & Metabolism Journal
Nagaaki Tanaka, Daisuke Yabe, Kenta Murotani, Shinji Ueno, Hitoshi Kuwata, Yoshiyuki Hamamoto, Takeshi Kurose, Nobuo Takahashi, Tomoyuki Akashi, Takashi Matsuoka, Takeshi Osonoi, Masae Minami, Dai Shimono, Yutaka Seino
AIMS/INTRODUCTION: This multi-center, cross-sectional survey was initiated to evaluate self-monitoring of blood glucose (SMBG)-associated mental distress among patients with diabetes. Materials and Methods The survey was conducted in patients using SMBG with type 1 diabetes (T1D) and type 2 diabetes (T2D) recruited from 42 medical institutions. Profiles of Mood States 2 (POMS2) and diabetes therapy-related QOL (DTR-QOL) questionnaires were used to evaluate mood status and health-related QOL...
March 1, 2018: Journal of Diabetes Investigation
Roozbeh Hajiraissi, Marcel Hanke, Yu Yang, Belma Duderija, Alejandro Gonzalez Orive, Guido Grundmeier, Adrian Keller
Aggregation and fibrillization of human islet amyloid polypeptide (hIAPP) plays an important role in the development of type 2 diabetes mellitus. Understanding the interaction of hIAPP with interfaces such as cell membranes at a molecular level therefore represents an important step toward new therapies. Here, we investigate the fibrillization of hIAPP at different self-assembled alkanethiol monolayers (SAMs) by quartz crystal microbalance with dissipation monitoring (QCM-D), atomic force microscopy (AFM), and polarization-modulated infrared reflection absorption spectroscopy (PM-IRRAS), respectively...
February 28, 2018: Langmuir: the ACS Journal of Surfaces and Colloids
S Finer, P Robb, K Cowan, A Daly, K Shah, A Farmer
AIMS: To describe processes and outcomes of a priority setting partnership to identify the 'top 10 research priorities' in Type 2 diabetes, involving people living with the condition, their carers, and healthcare professionals. METHODS: We followed the four-step James Lind Alliance Priority Setting Partnership process which involved: gathering uncertainties using a questionnaire survey distributed to 70 000 people living with Type 2 diabetes and their carers, and healthcare professionals; organizing the uncertainties; interim priority setting by resampling of participants with a second survey; and final priority setting in an independent group of participants, using the nominal group technique...
February 27, 2018: Diabetic Medicine: a Journal of the British Diabetic Association
Liana K Billings, Ankur Doshi, Didier Gouet, Alejandra Oviedo, Helena W Rodbard, Nikolaos Tentolouris, Randi Grøn, Natalie Halladin, Esteban Jodar
OBJECTIVE: In patients with uncontrolled type 2 diabetes on basal insulin, prandial insulin may be initiated. We assessed the efficacy and safety of initiating insulin degludec/liraglutide fixed-ratio combination (IDegLira) versus basal-bolus insulin. RESEARCH DESIGN AND METHODS: A phase 3b trial examined patients with uncontrolled type 2 diabetes on insulin glargine (IGlar U100) 20-50 units/day and metformin, randomized to IDegLira or IGlar U100 and insulin aspart four or fewer times per day...
February 26, 2018: Diabetes Care
Po Chung Cheng, Shang Ren Hsu, Shih Te Tu, Yun Chung Cheng, Yu Hsiu Liu
Background: Hypoglycemia occurs in an appreciable number of individuals with type 2 diabetes mellitus (T2DM) who are receiving glycemic therapy. Iatrogenic hypoglycemia induces not only complications but also a substantial medical expense. Intervention for relevant risk factors may help avert severe hypoglycemia and enhance quality of life in at-risk individuals. This study investigates the relationship between body mass index (BMI) and plasma glucose concentration during iatrogenic hypoglycemia in people with T2DM...
2018: PeerJ
Eleanor M Scott, Rudy W Bilous, Alexandra Kautzky-Willer
BACKGROUND: Accuracy of the FreeStyle Libre™ Flash Glucose Monitoring System has not been evaluated in pregnant women with diabetes. The aim of this study was to determine accuracy (compared to self-monitoring of blood glucose [SMBG]), clinical safety, and acceptability of the FreeStyle Libre System when used at home by this population. MATERIALS AND METHODS: Seventy-four participants, with type 1 (T1D, n = 24), type 2 (T2D, n = 11), or gestational (n = 39) diabetes, were enrolled across 13 sites (9 in United Kingdom, 4 in Austria)...
February 22, 2018: Diabetes Technology & Therapeutics
Dina H Griauzde, Jeffrey T Kullgren, Brad Liestenfeltz, Caroline Richardson, Michele Heisler
Background: Rates of participation in Diabetes Prevention Programs (DPPs) are low. This may be due, in part, to low levels of autonomous motivation (i.e., motivation that arises from internal sources and sustains healthy behaviors over time) to prevent type 2 diabetes (T2DM) among many individuals with prediabetes. Mobile health (mHealth) technologies that incorporate principles from the Self-Determination Theory offer an effective and scalable approach to increase autonomous motivation levels...
2018: Pilot and Feasibility Studies
Yanbing Zeng, Jielong Wu, Yaofeng Han, Fan Chen, Lele Chen, Shuyu Yang, Ya Fang
BACKGROUND: To examine the combined effect of self-monitoring of blood glucose (SMBG) and educational attainment on glycemic control in type 2 diabetes mellitus (T2DM) patients. METHODS: A cross-sectional survey was performed among community residents with T2DM. Good glycemic control was defined as hemoglobin A1c (HbA1c) levels below 7% in the most recent measurement. Multivariable logistic regression was used to examine associations of glycemic control with SMBG, educational attainment, and their combined effects by controlling for certain covariates, with further stratification by sex...
February 15, 2018: Journal of Diabetes
Sıddıka Gedik, Deniz Kocoglu
INTRODUCTION: This study aims to determine the disease management self-efficacy level for patients with type 2 diabetes living in a rural area of Turkey. METHODS: The study sample consisted of 216 adult patients with type 2 diabetes. Data were collected between April and June of 2015 using the Self-Efficacy Scale for Type 2 Diabetes. The relationship between independent variables and self-efficacy level was evaluated with t-test and one-way ANOVA in independent groups...
February 2018: Rural and Remote Health
Ying Li, Tao Cui, Xiaodong Kong, Xiulin Yi, Dexin Kong, Jianning Zhang, Changxiao Liu, Min Gong
The multiple physiologic characteristics of glucagon-like peptide 1 (GLP-1) make it a promising drug candidate for treating type 2 diabetes mellitus. However, the half-life of GLP-1 is short as a result of degradation by dipeptidyl peptidase IV and renal clearance. Stabilizing GLP-1 is therefore critical for its use in drug development. Self-assembling peptides are a class of peptides that undergo spontaneous assembly into ordered nanostructures. Recently, studies of self-assembling peptides as drug carriers have increased because of their enhanced stability...
January 17, 2018: FASEB Journal: Official Publication of the Federation of American Societies for Experimental Biology
Daniel Mønsted Shabanzadeh
Gallstone disease is highly prevalent in Denmark and other countries of northern Europe, and cholecystectomy for the treatment of clinical gallstone disease is one the most frequently performed surgical procedures. Research efforts for the identification of mechanisms involved in gallstone formation have a long history and the most established include bile cholesterol saturation, gallbladder motor function, and the enterohepatic circulation of secondary bile salts produced by fecal microbiota. A small number of determinants that are believed to affect these mechanisms have been identified until now...
February 2018: Danish Medical Journal
Pennie J Taylor, Campbell H Thompson, Grant D Brinkworth
This narrative review discusses the role of Continuous Glucose Monitoring (CGM) in glycaemic and weight control and lifestyle behaviour adherence in adults with type 2 diabetes (T2D). A literature search from January 2001 to November 2017 was conducted (MEDLINE, CINAHL, Web of Science and Scopus). Eligible studies were trials evaluating the use of CGM with the aim of achieving glucose control or lifestyle-related treatment adherence over a period of ≥8 weeks in adults with T2D compared to usual care or another comparison intervention OR observational trials reporting CGM user experience...
January 30, 2018: Journal of Diabetes Investigation
Johannes Vegt, Paul C Guest
There is a strong association between a suboptimal maternal environment and increased risk of developing age-associated diseases such as type 2 diabetes, obesity, and cardiovascular disease in the offspring. Blood clotting time may be altered in all of these conditions, and it is also an important factor that requires monitoring in postoperative and cardiovascular disorder patients who are on coagulant medications. This chapter describes patient self-management of blood coagulation activity using a test strip device and the Coagu app...
2018: Methods in Molecular Biology
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