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https://www.readbyqxmd.com/read/27836795/ultrasound%C3%A2-for%C3%A2-patients%C3%A2-in-a-high-hiv-tb-prevalence-setting-a%C3%A2-needs-assessment-and-review-of-focused-applications-for-sub-saharan-africa
#1
REVIEW
Tom Heller, Eric A Mtemang'ombe, Michaëla A M Huson, Charlotte C Heuvelings, Sabine Bélard, Saskia Janssen, Sam Phiri, Martin P Grobusch
Ultrasound is increasingly used in point-of-care applications and has great potential to support the diagnosis of infectious diseases, especially in resource-limited settings. We performed a cross-sectional study including 100 Malawian patients with a clinical indication for ultrasound and reviewed the literature on point-of-care ultrasound (POCUS) in Sub-Saharan Africa to establish its applicability, most frequent indications, findings, and implications for treatment, and therefore relevance in POCUS curricula, with a main focus on infectious diseases...
November 8, 2016: International Journal of Infectious Diseases: IJID
https://www.readbyqxmd.com/read/26487500/beh%C3%A3-et-s-syndrome-a-critical-digest-of-the-2014-2015-literature
#2
REVIEW
Gulen Hatemi, Emire Seyahi, Izzet Fresko, Rosaria Talarico, Vedat Hamuryudan
Several studies were published last year which focused on the epidemiology, immunopathogenesis, genetics, clinical manifestations and management of Behçet's syndrome. Recent epidemiologic studies support the earlier contention that the frequency of BS increases from North to South in Europe, BS is rare in Sub-Saharan Africa, it follows a more severe course among young men, especially if the disease onset is at a young age and that in European countries, the frequency is higher among immigrants from BS prevalent countries compared to locals living in the same environment...
November 2015: Clinical and Experimental Rheumatology
https://www.readbyqxmd.com/read/26284719/tinzaparin-vs-warfarin-for-treatment-of-acute-venous-thromboembolism-in-patients-with-active-cancer-a-randomized-clinical-trial
#3
RANDOMIZED CONTROLLED TRIAL
Agnes Y Y Lee, Pieter W Kamphuisen, Guy Meyer, Rupert Bauersachs, Mette S Janas, Mikala F Jarner, Alok A Khorana
IMPORTANCE: Low-molecular-weight heparin is recommended over warfarin for the treatment of acute venous thromboembolism (VTE) in patients with active cancer largely based on results of a single, large trial. OBJECTIVE: To study the efficacy and safety of tinzaparin vs warfarin for treatment of acute, symptomatic VTE in patients with active cancer. DESIGN, SETTINGS, AND PARTICIPANTS: A randomized, open-label study with blinded central adjudication of study outcomes enrolled patients in 164 centers in Asia, Africa, Europe, and North, Central, and South America between August 2010 and November 2013...
August 18, 2015: JAMA: the Journal of the American Medical Association
https://www.readbyqxmd.com/read/26123609/perceived-barriers-in-the-use-of-ultrasound-in-developing-countries
#4
Sachita Shah, Blaise A Bellows, Adeyinka A Adedipe, Jodie E Totten, Brandon H Backlund, Dana Sajed
BACKGROUND: Access to ultrasound has increased significantly in resource-limited settings, including the developing world; however, there remains a lack of sonography education and ultrasound-trained physician support in developing countries. To further investigate this potential knowledge gap, our primary objective was to assess perceived barriers to ultrasound use in resource-limited settings by surveying care providers who practice in low- and middle-income settings. METHODS: A 25-question online survey was made available to health care providers who work with an ultrasound machine in low- and middle-income countries (LMICs), including doctors, nurses, technicians, and clinical officers...
December 2015: Critical Ultrasound Journal
https://www.readbyqxmd.com/read/26057489/impact-of-sickle-cell-trait-on-the-thrombotic-risk-associated-with-non-o-blood-groups-in-northern-nigeria
#5
Sagir G Ahmed, Modu B Kagu, Umma A Ibrahim, Audu A Bukar
BACKGROUND: The non-O blood group is an established risk factor for deep vein thrombosis (DVT), while controversy surrounds the role of sickle cell trait (SCT) as a risk factor for DVT. We hypothesised that if SCT is a risk factor for DVT, individuals with non-O blood groups and SCT (Hb AS) would have a higher risk of DVT than their counterparts with non-O blood groups and normal haemoglobin phenotype (Hb AA). MATERIALS AND METHODS: We retrospectively analysed the prevalence of SCT and non-O blood groups among 148 DVT patients with control subjects in order to determine the role of SCT as a risk factor for DVT and its impact on the risk of DVT among patients with non-O blood groups...
October 2015: Blood Transfusion, Trasfusione del Sangue
https://www.readbyqxmd.com/read/23080367/african-caribbean-ethnicity-is-associated-with-a-hypercoagulable-state-as-measured-by-thrombin-generation
#6
Lara N Roberts, Raj K Patel, Paradzai Chitongo, Lynda Bonner, Roopen Arya
African-Caribbean ethnicity is associated with an increased risk of both first and recurrent venous thromboembolism (VTE). The aim of this study was to evaluate thrombin generation in African-Caribbeans compared with whites in patients with deep vein thrombosis (DVT) and healthy volunteers. Thrombin generation was measured in a case-control study of 80 patients who had completed anticoagulation therapy for a first DVT (50 white and 30 African-Caribbean) and 66 controls. Peak thrombin with and without thrombomodulin was significantly higher in African-Caribbeans with DVT compared with whites with DVT (P < 0...
January 2013: Blood Coagulation & Fibrinolysis: An International Journal in Haemostasis and Thrombosis
https://www.readbyqxmd.com/read/22310439/dvt-prophylaxis-in-relation-to-patient-risk-profiling-tune-in-study
#7
MULTICENTER STUDY
Pieter Wessels, Wayne Jonathan Riback
BACKGROUND: Patients in acute hospital care show a high risk for venous thromboembolism (VTE); 52% of patients globally are at risk, with approximately only half receiving appropriate prophylaxis. OBJECTIVES: The TUNE-IN study's primary objective was to evaluate the use of VTE prophylaxis in the private sector in South Africa in hospitalised patients in relation to patient risk profile, via both a clinical assessment and utilising a modified risk assessment model (RAM)...
February 2012: South African Medical Journal, Suid-Afrikaanse Tydskrif Vir Geneeskunde
https://www.readbyqxmd.com/read/21674133/pulmonary-thromboembolism-in-an-east-african-tertiary-referral-hospital
#8
Julius A Ogeng'o, Moses M Obimbo, Beda O Olabu, Patrick M Gatonga, Denis Ong'era
Pulmonary thromboembolism (PTE) is a frequent cause of mortality in Kenya, but its characteristics are hardly reported in Subsaharan Africa. To describe the pattern of PTE among black Africans, in a Kenyan referral hospital. Retrospective study at Kenyatta National Hospital (KNH), Nairobi, Kenya. Records of patients seen between January 2005 and December 2009 were examined for mode of diagnosis, comorbidities, age, gender, treatment and outcome. Data were analyzed using SPSS version 15.0 and are presented in tables and bar charts...
October 2011: Journal of Thrombosis and Thrombolysis
https://www.readbyqxmd.com/read/20886182/the-effect-of-initiating-combined-antiretroviral-therapy-on-endothelial-cell-activation-and-coagulation-markers-in-south-african-hiv-infected-individuals
#9
Eefje Jong, Susan Louw, Eric C M van Gorp, Joost C M Meijers, Hugo ten Cate, Barry F Jacobson
An increased incidence of venous thromboembolism (VTE) is observed in human immunodeficiency virus (HIV)-infected patients. Only a limited number of studies described the effect of combined antiretroviral therapy (cART) on coagulation markers. In a prospective cohort study in cART-naive South African HIV-infected individuals the effect of initiating cART on markers of endothelial cell activation, coagulation and natural anticoagulation was studied. These markers were compared to the reference ranges for an HIV-uninfected control population recruited from hospital staff...
December 2010: Thrombosis and Haemostasis
https://www.readbyqxmd.com/read/17895501/human-immunodeficiency-virus-infection-and-acute-deep-vein-thromboses
#10
Susan Louw, Barry F Jacobson, Harry Büller
Abnormalities that predispose to a hypercoagulable state with an increased incidence of venous thrombosis have been described in human immunodeficiency virus (HIV) infections and are associated with an increased mortality. A recent systematic review by Klein et al concluded that further studies are essential to elucidate the link between HIV infection and deep vein thrombosis (DVT). We prospectively evaluated 24 consecutive, active people presenting with an acute DVT; 13 consented to HIV testing, revealing an HIV prevalence of 84% (95% confidence interval [CI], 0...
July 2008: Clinical and Applied Thrombosis/hemostasis
https://www.readbyqxmd.com/read/9254816/the-cost-and-benefit-of-prophylaxis-against-deep-vein-thrombosis-in-elective-hip-replacement-dvt-pe-prophylaxis-consensus-forum
#11
REVIEW
T Abdool-Carrim, H Adler, P Becker, M Carides, J Ginsberg, R Golele, G Grobler, E Immelman, H Louwrens, M Lukhele, M Veller, K Watt, F Weber, E Williams
UNLABELLED: A consensus forum was convened to evaluate the economic considerations associated with prophylaxis against thrombo-embolic disease in patients undergoing hip replacement therapy in South Africa. This forum consists of orthopaedic surgeons, vascular surgeons and a statistician. METHODS: The forum was instructed to evaluate the economic costs of the commonly used forms of prophylaxis of thrombo-embolism in patients undergoing hip replacement surgery in South Africa, looking at short-term events only...
May 1997: South African Medical Journal, Suid-Afrikaanse Tydskrif Vir Geneeskunde
https://www.readbyqxmd.com/read/7500748/venous-thromboembolic-disease-and-combined-oral-contraceptives-results-of-international-multicentre-case-control-study-world-health-organization-collaborative-study-of-cardiovascular-disease-and-steroid-hormone-contraception
#12
MULTICENTER STUDY
(no author information available yet)
The composition and use of oral contraceptives (OCs) have changed since their cardiovascular side-effects were established 20 years ago. This report describes the risk of idiopathic venous thromboembolic (VTE) events (deep vein thrombosis [DVT] and/or pulmonary embolism [PE]) in association with current use of combined OCs among 1143 cases aged 20-44 and 2998 age-matched controls, as evaluated in a hospital-based, case-control study in 21 centres in Africa, Asia, Europe, and Latin America. OC use was associated with an increased risk of VTE in Europe (odds ratio 4...
December 16, 1995: Lancet
https://www.readbyqxmd.com/read/3390675/incidence-of-deep-vein-thrombosis-after-major-abdominal-surgery-in-brisbane
#13
P G Reasbeck, S Guerrini, J Harper, R Sackelariou, J F McCaffrey
There is some evidence that postoperative deep vein thrombosis (DVT) may be commoner in cool than in warm climates. To determine whether this complication is less common in the subtropical climate of Brisbane than in more temperate locations, the incidence of DVT after major abdominal surgery was assessed by 125I fibrinogen scanning. In order to avoid overestimating the incidence of DVT, abnormal scans were accepted as diagnostic only if the DVT was confirmed by venography or if the abnormality on the scan fulfilled more stringent criteria than have previously been applied...
May 1988: British Journal of Surgery
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