Wen-Jie Tang, Jin-Xin Zhang, Mei-Ling Wen, Yan Wei, Ting-Ting Tang, Tian-Tian Yang, Hao-Ting Bai, Chai-Qiong Guo, Xiang Gao, Zi-Chen Wang, Lu-Dan Xu, Yang Liu, Mei-Wen An
Electrospun fibres have been widely used as skin dressings due to their unique structur. However, due to the lack of intrinsic antimicrobial activity, it is easy for the wound to become infected. Bacterial infection, which leads to chronic inflammation, severely hinders the normal process of skin regeneration. In this study, a polyvinyl alcohol/chitosan (PVA/CS) composite films with chemical sterilization and near-infrared (NIR) photothermal antibacterial activity was fabricated by electrospinning. Graphene oxide (GO), a photosensitiser, was incorporated into the films, and lanthanum chloride (Lacl3 ) as a chemical antibacterial agent was also doped in the electrospun films...
October 9, 2023: Journal of the Mechanical Behavior of Biomedical Materials